ES2000704A6 - Procedimiento para al obtencion de derivados de piridina - Google Patents

Procedimiento para al obtencion de derivados de piridina

Info

Publication number
ES2000704A6
ES2000704A6 ES8600429A ES8600429A ES2000704A6 ES 2000704 A6 ES2000704 A6 ES 2000704A6 ES 8600429 A ES8600429 A ES 8600429A ES 8600429 A ES8600429 A ES 8600429A ES 2000704 A6 ES2000704 A6 ES 2000704A6
Authority
ES
Spain
Prior art keywords
alkyl
pyridine derivatives
hydrogen
group
fungicidal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES8600429A
Other languages
English (en)
Inventor
Beat Zehnder
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of ES2000704A6 publication Critical patent/ES2000704A6/es
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/28Radicals substituted by singly-bound oxygen or sulphur atoms
    • C07D213/30Oxygen atoms
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/34Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom
    • A01N43/40Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom six-membered rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36Radicals substituted by singly-bound nitrogen atoms
    • C07D213/42Radicals substituted by singly-bound nitrogen atoms having hetero atoms attached to the substituent nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/44Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
    • C07D213/46Oxygen atoms
    • C07D213/48Aldehydo radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/44Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
    • C07D213/46Oxygen atoms
    • C07D213/50Ketonic radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/89Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Pyridine Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

EL INVENTO SE REFIERE A UN PROCEDIMIENTO PARA LA OBTENCION DE NUEVOS DERIVADOS DE PIRIDINA, DE FORMULA GENERAL EN DONDE R, R1, R2 Y R3 TIENEN EL SIGNIFICADO EXPUESTO EN LA DESCRIPCION, Y DE SALES N-AMINO Y SALES DE ADICION DE ESTOS COMPUESTOS CARACTERIZADO PORQUE SE HACE REACCIONAR UNA CETONA DE FORMULA GENERAL EN DONDE R Y R1 TIENEN EL SIGNIFICADO ANTES INDICADO, CON UNA SAL DE METAL APROPIADO, ESPECIALMENTE LA SAL LITICA, DE UN ETER ENOLICO DE FORMULA GENERAL CH(OR4)FCHR5III EN PRESENCIA DE UN DILUYENTE INERTE, ESPECIALMENTE UN DISOLVENTE ORGANICO APROTICO, A TEMPERATURA DE C80JC A 0JC, DURANTE UN TIEMPO ADECUADO. LA N-AMIDACION DE UN COMPUESTO DE FORMULA I CON UN DERIVADO AMINICO DE FORMULA GENERAL H2N-XIV SE LLEVA A CABO EN PRESENCIA DE UN DILUYENTE ORGANICO INERTE A TEMPERATURA ENTRE 0JC Y LA TEMPERATURA DE REFLUJO DEL DISOLVENTE EMPLEADO. ESTOS NUEVOS DERIVADOS DE PIRIDINA POSEEN NOTABLE ACTIVIDAD, FUNGICIDA Y POR CONSIGUIENTE SE HA PREVISTO SU UTILIZACION PARA EL CONTROL DE HONGOSEN AGRICULTURA, EN HORTICULTURA Y EN LA ELABORACION DE LA MADERA.
ES8600429A 1985-07-22 1986-07-21 Procedimiento para al obtencion de derivados de piridina Expired ES2000704A6 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH317785 1985-07-22
CH206586 1986-05-22

Publications (1)

Publication Number Publication Date
ES2000704A6 true ES2000704A6 (es) 1988-03-16

Family

ID=25689407

Family Applications (2)

Application Number Title Priority Date Filing Date
ES8600429A Expired ES2000704A6 (es) 1985-07-22 1986-07-21 Procedimiento para al obtencion de derivados de piridina
ES878703523A Expired ES2006238A6 (es) 1985-07-22 1987-12-04 Procedimiento para la preparacion de derivados de piridina como divisional de la patente numero 86 00429 del 21 de julio de 1986.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES878703523A Expired ES2006238A6 (es) 1985-07-22 1987-12-04 Procedimiento para la preparacion de derivados de piridina como divisional de la patente numero 86 00429 del 21 de julio de 1986.

Country Status (7)

Country Link
US (1) US4699652A (es)
EP (1) EP0209854A3 (es)
AU (1) AU6041586A (es)
ES (2) ES2000704A6 (es)
HU (1) HUT41216A (es)
IL (1) IL79434A0 (es)
PT (1) PT83033B (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU554104B2 (en) * 1981-09-01 1986-08-07 F. Hoffmann-La Roche Ag Heterocyclic compounds and fungicides containing same
GB8714013D0 (en) * 1987-06-16 1987-07-22 Ici Plc (substituted-aralkyl)heterocyclic compounds
GB8814639D0 (en) * 1988-06-20 1988-07-27 Ici Plc Heterocyclic tertiary alcohol derivatives
DE3827135A1 (de) * 1988-08-10 1990-02-15 Bayer Ag Substituierte 3-pyridyl- bzw. 3-pyrimidyl-4-(1,3-dioxolanyl)-carbinole, verfahren zu ihrer herstellung und ihre verwendung als schaedlingsbekaempfungsmittel
DE3831402A1 (de) * 1988-09-15 1990-03-22 Bayer Ag Substituierte pyrimidyl- bzw. pyridylalkinole, verfahren zu ihrer herstellung und ihre verwendung in schaedlingsbekaempfungsmitteln
IL96706A (en) * 1989-12-29 1995-06-29 Basf Ag 3-Transformed pyridines, their production and use as fungicides
DE4121049A1 (de) * 1991-06-26 1993-01-07 Basf Ag Neue 3-substituierte pyridinmethanole und diese enthaltende fungizide
DE10248335A1 (de) * 2002-10-17 2004-05-06 Bayer Ag Fungizide Wirkstoffkombinationen
MXPA06002500A (es) * 2003-09-18 2006-06-20 Basf Ag Nuevas sulfonamidas como agentes fitosanitarios.
US8268820B2 (en) * 2009-03-26 2012-09-18 Hoffmann-La Roche Inc. 2,3-diaryl- or heteroaryl-substituted 1,1,1-trifluoro-2-hydroxypropyl compounds
US8138189B2 (en) * 2009-03-26 2012-03-20 Hoffman-La Roche Inc. Substituted benzene compounds as modulators of the glucocorticoid receptor
CN108948247B (zh) * 2017-05-27 2021-12-21 北京化工大学 一种低分子量环氧基封端的聚丁二烯、制备方法及应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0062238B1 (de) * 1981-03-30 1985-01-30 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft 1,3-Dioxolan-Derivate, Herstellung dieser Verbindungen, fungizide Mittel, die diese Verbindungen als Wirkstoffe enthalten sowie Verwendung solcher Verbindungen bzw. Mittel zur Bekämpfung von Fungi in der Landwirtschaft und im Gartenbau
DE3126819A1 (de) * 1981-07-08 1983-01-27 Basf Ag, 6700 Ludwigshafen Pyridincarbinole, verfahren zu ihrer herstellung und diese enthaltende fungizide

Also Published As

Publication number Publication date
US4699652A (en) 1987-10-13
EP0209854A2 (de) 1987-01-28
EP0209854A3 (de) 1987-10-07
ES2006238A6 (es) 1989-04-16
HUT41216A (en) 1987-04-28
PT83033B (en) 1988-07-08
PT83033A (en) 1986-08-01
IL79434A0 (en) 1986-10-31
AU6041586A (en) 1987-01-29

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19980504