ES2000382A6 - Production of substituted phenethylamine derivative - Google Patents

Production of substituted phenethylamine derivative

Info

Publication number
ES2000382A6
ES2000382A6 ES8600685A ES8600685A ES2000382A6 ES 2000382 A6 ES2000382 A6 ES 2000382A6 ES 8600685 A ES8600685 A ES 8600685A ES 8600685 A ES8600685 A ES 8600685A ES 2000382 A6 ES2000382 A6 ES 2000382A6
Authority
ES
Spain
Prior art keywords
formula
reduced
deriv
phenethylamine
aminopropyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES8600685A
Other languages
Spanish (es)
Inventor
Takashi Fujikura
Kunihiro Niigata
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yamanouchi Pharmaceutical Co Ltd
Original Assignee
Yamanouchi Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=17263445&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2000382(A6) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Yamanouchi Pharmaceutical Co Ltd filed Critical Yamanouchi Pharmaceutical Co Ltd
Publication of ES2000382A6 publication Critical patent/ES2000382A6/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/30—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/37—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring

Abstract

A phenethylamine deriv. of formula (I) is reacted with a substituted phenoxyacetaldehyde of formula (II) and the resulting intermediate is reduced to obtain a substd. phenethylamine deriv. of formula (III) (where R1 is lower alkoxy; R2 is lower alkyl; R3 is lower alkoxy). - (I) is pref. R(-)-5-(2 aminopropyl) 2-methoxybenzenesulfonamide or R(+)-5-(2-aminopropyl) 2-methoxy benzeneulfonamide. The reaction of (I) and (II) is effected in an inert solvent (methanol, ether, benzene at room temp. or under heat. After isolation, the intermediate is reduced by catalytic redn. in the presence of a catalyst of platinum oxide, Pd/C or Raney nickel, or reduced with a metal hydride such as sodium borohydride, lithium borohydride or lithium aluminium hydride.
ES8600685A 1985-11-13 1986-07-29 Production of substituted phenethylamine derivative Expired ES2000382A6 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP60254326A JPS62114952A (en) 1985-11-13 1985-11-13 Production of substituted phenethylamine derivative

Publications (1)

Publication Number Publication Date
ES2000382A6 true ES2000382A6 (en) 1988-02-16

Family

ID=17263445

Family Applications (1)

Application Number Title Priority Date Filing Date
ES8600685A Expired ES2000382A6 (en) 1985-11-13 1986-07-29 Production of substituted phenethylamine derivative

Country Status (5)

Country Link
JP (1) JPS62114952A (en)
KR (1) KR940007746B1 (en)
AT (1) AT397960B (en)
CA (1) CA1282077C (en)
ES (1) ES2000382A6 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2200699A1 (en) * 2002-07-12 2004-03-01 Ragactives Sl Method of separating r(-)- and s(+)-5- 2- 2-(2-ethoxyphenoxy)ethyl amino propyl-2-methoxybenzene-sulphonamide

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4971990A (en) * 1988-02-19 1990-11-20 Hokuriku Pharmaceutical Co., Ltd. Phenoxyethylamine derivatives, for preparing the same and composition for exhibiting excellent α1 -blocking activity containing the same
US5288759A (en) * 1992-08-27 1994-02-22 Alcon Laboratories, Inc. Use of certain sulfamoyl-substituted phenethylamine derivatives to reverse drug-induced mydriasis
TW536402B (en) 1998-06-26 2003-06-11 Yamanouchi Pharma Co Ltd Pharmaceutical composition for the therapy of voiding dysfunction
KR100525493B1 (en) 2001-02-23 2005-11-02 연성정밀화학(주) Process for preparing sulfamoyl-substituted phenethylamine derivatives
CZ20013848A3 (en) * 2001-10-25 2003-05-14 Léčiva, A.S. Process for preparing (R)-(-)-5-[2-[2-(2-ethoxyphenoxy)ethylamino]propyl]-2-methoxybenzene sulfonamide
WO2004016582A1 (en) * 2002-08-14 2004-02-26 Natco Pharma Limited An improved process for the preparation of tamsulosin hydrochloride
KR100503639B1 (en) 2003-02-12 2005-07-26 보령제약 주식회사 A purification process of Tamsulosin
WO2005056521A1 (en) 2003-12-09 2005-06-23 Cj Corporation Method of preparing optically pure phenethylamine derivatives
SI21655A (en) * 2003-12-29 2005-06-30 LEK farmacevtska dru�ba d.d. Synthesis of optically pure (r)-5-(2-aminopropyl)-methoxybenzene sulphonamide
SI21656A (en) * 2003-12-29 2005-06-30 LEK farmacevtska družba d.d. Preparation of (r)-5-(2-(2-(2-ethoxyphenoxy)ethylamino)-1-propyl)-2-methoxybenzene sulphonamide hydrochloride of high chemical purity
CZ2004197A3 (en) * 2004-02-05 2005-08-17 Zentiva, A. S. Process for preparing (R)-(-)-5-(2-aminopropyl)-2-methoxybenzenesulfonamide
US20080033208A1 (en) * 2004-02-23 2008-02-07 Dilipkumar Chandubhai Ramolia Process for Manufacturing Optically Pure (R) or (S)-5-(2-Aminopropyl)-2-Methoxybenzene Sulfonamide
WO2006004093A1 (en) * 2004-07-07 2006-01-12 Hamari Chemicals, Ltd. Process for producing optically active phenylpropylamine derivative
CN100545148C (en) 2004-08-16 2009-09-30 神隆新加坡私人有限公司 A kind of synthetic method of anti-BPH (benign prostatic hyperplasia) medicament Tamsulosin
US8273918B2 (en) 2005-09-12 2012-09-25 Avrobindo Pharma Ltd. Process for preparing tamsulosin hydrochloride
WO2008152653A2 (en) * 2007-06-11 2008-12-18 Matrix Laboratories Ltd An improved process for the preparation of tamsulosin hydrochloride
AU2010211725C1 (en) 2009-02-04 2014-10-16 Astellas Pharma Inc. Pharmaceutical composition for oral administration
EP2255793A1 (en) 2009-05-28 2010-12-01 Krka Tovarna Zdravil, D.D., Novo Mesto Pharmaceutical composition comprising tamsulosin
US8471039B2 (en) * 2009-09-12 2013-06-25 Sandoz Ag Process for the preparation of indoline derivatives and their intermediates thereof
DE202023102187U1 (en) 2023-04-25 2023-05-02 Nusrath Anjum Derivative formulation based on tamsulosin

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1147342A (en) * 1977-10-12 1983-05-31 Kazuo Imai Process of producing novel phenylethanolamine derivatives
US4558156A (en) * 1980-02-08 1985-12-10 Yamanouchi Pharmaceutical Co., Ltd. Sulfamoyl-substituted phenethylamine derivatives
JPS56110665A (en) * 1980-02-08 1981-09-01 Yamanouchi Pharmaceut Co Ltd Sulfamoyl-substituted phenetylamine derivative and its preparation

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2200699A1 (en) * 2002-07-12 2004-03-01 Ragactives Sl Method of separating r(-)- and s(+)-5- 2- 2-(2-ethoxyphenoxy)ethyl amino propyl-2-methoxybenzene-sulphonamide
WO2004006829A3 (en) * 2002-07-12 2004-04-08 Ragactives Sl Method of separating r(-)- and s(+)-5-[2-[[2-(2-ethoxyphenoxy)ethyl]amino]propyl-2-methoxybenzene-sulphonamide
US7105698B2 (en) 2002-07-12 2006-09-12 Ragactives, S.L. Process for the separation of R(-)-and S(+)-5-[2-[[2-(2-ethoxyphenoxy)ethyl]amino]propyl]-2- methoxybenzenesulfonamide

Also Published As

Publication number Publication date
KR870004949A (en) 1987-06-02
AT397960B (en) 1994-08-25
ATA203286A (en) 1993-12-15
JPH0137391B2 (en) 1989-08-07
CA1282077C (en) 1991-03-26
KR940007746B1 (en) 1994-08-24
JPS62114952A (en) 1987-05-26

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20060731