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Leo Pharma AS
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Leo Pharmaceutical Products Ltd AS
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Publication of ES193814A1publicationCriticalpatent/ES193814A1/en
Un metodo de producir amino esteres de penicilina en el cual una sal de penicilina se hace reaccionar con un haluro de la fórmula ** (Ver fórmula)**donde X es halógeno R 1 es un residuo alcohílica divalente y r2 y R3 son alcohilo o aralcohilo o en el cual R 2/sub> y r3 junto con el átomo de nitrógeno forman un anillo heterocíclico o en el cual un anhídrido mixto de penicilina y un ácido carboxílico alifático se hace reaccionar con un amino-alcohol de la fórmula ** (Ver fórmula)**.A method of producing penicillin amino esters in which a penicillin salt is reacted with a halide of the formula ** (See formula) ** where X is halogen R 1 is a divalent alcoholic residue and r2 and R3 are alcohol or aralkyl or in which R 2 / sub> and r3 together with the nitrogen atom form a heterocyclic ring or in which a mixed anhydride of penicillin and an aliphatic carboxylic acid is reacted with an amino-alcohol of the formula ** ( See formula) **.
ES0193814A1949-07-071950-07-06
A METHOD FOR THE PRODUCTION OF PENICILLIN AMINOESTERS
ExpiredES193814A1
(en)
Improvements in or relating to the preparation of chloro-acetoacetamides and to substituted dioxolan derivatives of acetic acid esters as intermediates in said preparation
Procedure for the preparation of 1, 4-difenil-3, 5-diquetopirazolidina and its derivatives (Machine-translation by Google Translate, not legally binding)