ES1285294U - FLOW GENERATION DEVICE FOR NON-INVASIVE VENTILATION OR HIGH FLOW OXYGEN THERAPY AND RELATED FLOW MANAGEMENT SYSTEM (Machine-translation by Google Translate, not legally binding) - Google Patents

Abstract

Flow generation equipment (1, 101, 101', 201) for non-invasive ventilation or high-flow oxygen therapy comprising: - at least one Venturi device (2, 204) to supply a gas mixture; - at least one air inlet (3) in said Venturi device, comprising at least one constriction element (3A) to dose the amount of air sucked into said Venturi device (2, 204); - an interface element (12) that completely or partially covers the patient's respiratory tract and that comprises an inlet port for the fresh gas mixture (11); - a first conduit (10) for functionally connecting said Venturi device (2, 204) with said interface element (12); - at least one first flowmeter (5, 105, 203), associated with said Venturi device (2, 204) by means of at least one supply connection (4) and suitable for dosing said gas mixture. (Machine-translation by Google Translate, not legally binding)

Description

DESCRIPTION

FLOW GENERATION EQUIPMENT FOR NON-INVASIVE VENTILATION U

HIGH FLOW OXYGEN THERAPY AND FLOW MANAGEMENT SYSTEM

CORRESPONDENT

Area of application

The present invention relates to flow generation equipment for non-invasive ventilation or high-flow oxygen therapy.

The aforementioned device finds a useful application in particular, but not exclusively, in the field of equipment for medical treatment in a hospital setting, but it can also be used, obviously, in the home setting and in mobile emergency units.

State of the art

It is known in the present sector that a gas flow composed of variable concentrations of medical oxygen, if transported into the airways of a patient through a corresponding interface, can improve the clinical conditions of the patient himself. The presence of a continuous gas flow enriched with oxygen is the basis of the operation of the equipment known as CPAP (Continuous Positive Airway Pressure) used both in the home environment and in the pre-hospital or intra-hospital environment.

CPAP machines deliver a flow of pressurized gas through a face (or nasal) mask and tubing; the pressure of the air enriched with oxygen allows to improve the clinical conditions of the patient.

Equipment of this type generally comprises a ventilator, that is to say, a compressor unit that increases the pressure of the air in a few centimeters of water, a connection element to the patient and a tube connecting the ventilator to the patient.

CPAP (Continuous Positive Airway Pressure) equipment supplies a constant positive pressure with respect to atmospheric pressure. These also include equipment suitable for use with newborns through multiple interfaces that adhere completely or partially to the airways.

Apart from devices that generate continuous pressure (CPAP), more advanced equipment is also available that supplies the patient with additional pressure, such as VPAP or BPAP (Variable/Bilevel Positive Airway Pressure) and APAP (Automatic Positive Airway Pressure) equipment.

CPAP equipment is used in various fields; as home therapy for sleep apnea disorders, but also in a hospital or prehospital setting for pathologies such as ARDS (acute respiratory distress syndrome), pneumonia, acute respiratory failure, postoperative hypoxemia, some cases of outbreaks of COPD (obstructive pulmonary disease chronic), treatment of chest trauma with pulmonary contusions, pulmonary edema and atelectasis of various origins. In addition, they can be used as prevention of reintubation in patients who have run out of removing the mechanical ventilator.

Acute respiratory failure can be determined by various causes. When there is damage to the lung parenchyma, for example, associated with intraalveolar exudate, interstitial edema, reduction or lack of surface-active substance, the alveoli are more difficult to expand in the inspiratory stage and easier to collapse in the expiratory stage. Alveolar distention can be partially maintained with a pressure gradient (CPAP), between the interior of the respiratory system and the external environment, active for the entire duration of the respiratory cycle.

The pressure gradient prevents alveolar collapse at the end of expiration, keeping the end-expiratory volume higher and reducing the effort of inspiration with the consequent improvement in hypoxemia.

The use of a continuous flow of oxygen-enriched gas is not only the basis of the operation of CPAP systems, but also of the so-called high-flow oxygen therapy via nasal cannulas (High Flow Nasal Cannula - HFNC).

The interface that supplies high-flow oxygen therapy is made up of corresponding nasal cannulas that are fed with a mixture of gases enriched with oxygen in variable concentration (even up to 100%) with an adjustable flow, generally between 30 and 60 l/min.

High-flow oxygen therapy has experienced rapid diffusion in recent years thanks to its good tolerance by patients, ease of use and efficacy in the treatment of multiple pathologies, such as pneumonia, heart failure, post-extubation hypoxia.

Both CPAP systems and high-flow oxygen therapy systems require a large amount of oxygen-enriched gas to be fed.

To generate efficient flow, various systems are available, such as Venturi systems, turbine systems, and equipment requiring compressed medical gases. Venturi systems are widely used due to their low cost and ease of use.

However, currently used Venturi-based flow generators, while advantageous, are difficult to operate in terms of oxygen (O 2 ) titration and measurement of gas flow delivered to the patient.

The devices and methodologies currently used, although advantageous, are still inaccurate with regard to the titration of oxygen (O2) and the dosage of the air mixture to the patient.

For this reason, the problem on which the present invention is based is that of devising a device capable of overcoming the aforementioned drawbacks, managing, at the same time, to ensure the maintenance of a sufficient continuous positive pressure.

Another objective of the present invention is to provide equipment suitable for high-flow applications, that is, with a mixing flow rate equal to at least 15 l/min.

Yet another object is to provide equipment that is easy and comfortable to use by a user.

Lastly, another objective is to provide equipment that is easy to produce.

Summary of the invention

The idea of a solution on which the present invention is based is to provide equipment capable of efficiently supplying both the flow of a respiratory mixture and the titration of oxygen, in order to guarantee an adequate F Ó for therapy in course. The mentioned technical problem is solved by a flow generation equipment for non-invasive ventilation or high-flow oxygen therapy comprising at least one Venturi device, suitable for supplying a mixture of gases, at least one air inlet in the Venturi device comprising at least one constriction element to dose the amount of air sucked into the Venturi device, an interface element that completely or partially covers the patient's respiratory tract and that comprises an inlet mouth for the fresh gas mixture, a first suitable conduit to functionally connect the Venturi device with the interface element, at least one first flowmeter, associated to the Venturi device by means of at least one supply fitting and to dose the gas mixture.

Advantageously, this equipment enables its application in various operating modes, simply by putting the elements of the equipment into operation in different modes.

Preferably, the equipment according to the invention further comprises an outlet for excess gases and exhalation from the patient and a second conduit suitable for evacuating from said interface element the gases exhaled by the patient through the outlet for excess gases and of the patient's expiration.

More preferably, the equipment according to the invention further comprises a positive pressure maintenance valve connected to this outlet.

The inlet mouth can coincide with the outlet mouth, with a Y-junction that directs the flows differently.

Advantageously, the present solution enables a correct dosage of the mixture and a correct titration of oxygen inside the mixture, maintaining the desired positive pressure.

Furthermore, advantageously, the present solution makes it possible to apply the same equipment to different solutions that contemplate a different number of flowmeters without particular structural adaptations, but only by means of a simple regulation.

Preferably, the at least one first flowmeter is a high flow oxygen flowmeter capable of achieving flow rates of at least 15 l/min.

Advantageously, this solution is particularly suitable for all high-flow oxygen therapies and for non-invasive ventilation.

According to a first embodiment, the equipment according to the invention also includes a second flow meter, comprising a flexible connection that can be associated with at least one Venturi device; This second flowmeter is to increase the titration value of oxygen in said gas mixture.

Advantageously, the first flowmeter will serve as the "driver" source for the device. Venturi, while the second flowmeter will allow increasing regulation of the oxygen titration value in the mixture to be supplied to the patient through the use of the flexible connector for the connection of the port present in the Venturi device.

Preferably, the second flowmeter is a high flow oxygen flowmeter capable of achieving flow rates of at least 15 l/min.

Advantageously, also in this case such a solution is particularly suitable for all high-flow oxygen therapies and for non-invasive ventilation.

According to an alternative embodiment, instead, a single flowmeter is present, with the dosage obtained using the constriction element.

Therefore, the equipment according to the invention makes it possible to use one or two flowmeters indistinctly and, therefore, to be interchangeable for different types of operating modes, without this implying a structural difference, but simply requesting a different regulation.

In addition, according to a variant, the equipment, according to the invention, comprises at least one element for selecting the oxygen supply flow of the Venturi device, to regulate the oxygen titration of the gas mixture to be supplied to the patient in the presence of degree applications above 70%.

Advantageously, according to this embodiment in which the use of a single flowmeter is envisaged, the element for selecting the oxygen supply flow of the Venturi device makes it possible to adjust the oxygen titration value of the mixture to be supplied. the patient also in extreme conditions in which a large flow of pure oxygen is requested.

According to another alternative embodiment, in the equipment according to the invention said first flowmeter is integrated in said Venturi device and generates a drag flow that determines the mixture of air and oxygen.

Advantageously, this solution allows, with a single flowmeter, the use in CPAP therapy or high-flow oxygen therapy.

More preferably, the equipment according to the invention further comprises an oximeter connected in line with the Venturi device and suitable for measuring and monitoring the percentage of oxygen in the gas mixture supplied to the patient.

Advantageously, this makes it possible to constantly monitor the concentration of oxygen present in the supplied mixture.

Furthermore, preferably, the equipment according to the invention also comprises at least one antimicrobial filter to protect the patient, and to attenuate the noise of said equipment. Advantageously, this solution protects the patient from contamination by viruses or bacteria, while increasing the comfort of use by reducing the noise generated by the high flows.

More preferably, the at least one interface element of the equipment comprises a nasal mask or cannulae, an oral nasal mask or a helmet for CPAP therapy.

Alternatively, the at least one interface element is made up of an HFNC high-flow nasal cannula, with which it is possible to initiate high-flow oxygen therapy, thus providing the patient with non-invasive respiratory support with release of heated, humidified, oxygen-enriched air, when oxygen is requested at a higher flow rate.

This makes it possible to improve oxygenation, respiratory rate, dyspnea and patient comfort and helps to speed up patient rehabilitation after extubation, in different clinical settings, such as first aid, semi-intensive and intensive care, and the recovery room.

Advantageously, the equipment according to the invention is therefore suitable for a plurality of users and for a plurality of therapeutic modalities.

According to another aspect of the invention, a flow management system is provided for a device for non-invasive ventilation or high-flow oxygen therapy, comprising at least one carbon dioxide absorber, a recirculation circuit, comprising at least one conduit of suction and purge upstream of this carbon dioxide absorber, and a flow generation equipment according to what has been described above. Advantageously, such a system makes it possible to save the supplied oxygen. Other characteristics and advantages will appear mainly in the detailed description that appears below of a preferred, but not exclusive, embodiment of the equipment according to the present invention, in relation to the attached figures given by way of example, but not limitation.

Brief description of the drawings

In such drawings:

• figure 1 represents a schematic view of a first embodiment of a flow generation equipment for non-invasive ventilation or high-flow oxygen therapy according to the invention;

• Figures 2A, 2B, 2C, 2D schematically represent a series of respective comparative diagrams illustrating the variation in performance of the equipment in Figure 1 as the oxygen value setting varies.

• figure 3 represents a schematic view of a second embodiment of a flow generation equipment for non-invasive ventilation according to the invention;

• Figures 4A, 4B, 4C, 4D, 4E schematically represent a series of respective comparative diagrams illustrating the performance variation of the equipment of Figure 3 as the oxygen value setting varies;

• figure 5 represents a variation of the second embodiment of figure 3;

• figure 6 represents a schematic view of a third embodiment of a flow generation equipment for non-invasive ventilation according to the invention;

• figure 7 represents a schematic view of a flow management system with recirculation for a non-invasive ventilation equipment according to the invention, which is used in CPAP therapy.

Detailed description

In relation to the attached figures, 1 indicates in a global and schematic manner a first form of embodiment of a flow generation equipment for non-invasive ventilation, made according to the present invention.

In particular, in figure 1 a first form of embodiment is represented, hereinafter called for convenience "double flow meter".

This embodiment comprises a Venturi 2 device. The Venturi 2 device acts as a flow generator for non-invasive ventilation, being clearly shaped like a conduit to take advantage of the venturi effect.

The equipment 1 also comprises at least one air inlet 3, comprising at least one constriction element 3A to dose the amount of air sucked into the Venturi device 2.

The narrowing element 3A in the present description and in the figures is constituted by a manual adjustment element, but nothing prevents from proposing equivalent solutions, all included in the scope of the appended claims.

Furthermore, the Venturi device 2 is connected, by means of a supply connection 4, to a first flowmeter 5, directly interconnected to an oxygen source.

The first flowmeter 5 is preferably a high-flow flowmeter capable of reaching and managing flow rates of at least 15 l/min, or even others.

Even more, in the present embodiment the Venturi device 2 is connected, by means of a flexible connection 6, to a second flowmeter 7. This solution is, however, optional as will become clear following the description.

In the present embodiment, the supply fitting 4 and the flexible fitting 6 each comprise, respectively corresponding to the first flowmeter 5 and the second flowmeter 7, an outlet fitting 8, for example, of the 9/16 thread type. UNF (Unified Fine Threads). This is clearly an exemplary and non-limiting embodiment, multiple alternative forms of interconnection being possible.

The second flowmeter 7 is a high flow flowmeter capable of reaching and managing flow rates of at least 15 l/min.

The first flowmeter 5 serves as a "driver" source for the Venturi device 2.

The second flowmeter 7 allows, however, to increase the oxygen titration value of the mixture to be supplied to the patient through the flexible connection 6 connected to the Venturi device 2.

The Venturi device 2 further comprises a supply outlet 9 from which a first conduit 10 exits towards a fresh gas mixture inlet port 11 of an interface element 12 that completely or partially covers the patient's respiratory tract.

In any case, the equipment 1 according to the invention foresees the use in ventilation of a interface element 12 specific.

Interface element 12 may be selected, in the application of CPAP therapy, from a nasal mask, nasal cannulae, an oral nasal mask or a CPAP therapy helmet.

Naturally, nothing prohibits the use of different connection elements, also depending on future developments of medical therapies.

In an alternative embodiment (not shown), it is in fact possible to use an HFNC high-flow nasal cannula, with which it is possible to initiate high-flow oxygen therapy, thus providing the patient with respiratory support. non-invasive with release of heated, humidified, oxygen-enriched air.

This makes it possible to improve oxygenation, respiratory rate, dyspnea and patient comfort and helps to speed up the patient's rehabilitation after extubation.

However, the interface element 12 comprises, in the application of CPAP therapy and in the embodiments shown in the attached figures, an outlet 13 from which a second conduit 14 starts for excess gases and expiration. of the patient.

The inlet port 11 can coincide with the outlet port 13, with a Y-shaped branch that directs the flows differently.

A positive pressure maintenance valve, or PEEP valve, 15 is preferably associated with the outlet port 13 for the excess gases and the patient's expiration. Valve 15 is a device for maintaining positive end pressure. and attached to the outlet fitting of the mask or helmet for CPAP.

Consequently, the patient is supplied with a mixture of gases, suitably titrated in oxygen and dosed in l/min through the first flowmeter 5 and the second flowmeter 7, both for oxygen; in case you want to obtain the CPAP effect, it is obtained by evacuating, through the PEEP valve 15, the exhaled gases.

Furthermore, according to the present embodiment, the equipment comprises an oximeter 16, connected in line with the Venturi device 2, arranged in a substantially opposite position to that of the first flowmeter 5 and that of the second flowmeter 7.

The oximeter 16 makes it possible to constantly monitor the concentration of oxygen present in the mixture supplied to the patient.

Still further, according to the present embodiment, two antimicrobial filters 17 are preferably connected, respectively located one on the first conduit 10 and the other on the second conduit 14.

The antimicrobial filter 17 on the first duct 10, in addition to guaranteeing protection for the patient, makes it possible to attenuate the noise generated by the flow of the mixture, thus also obtaining greater acoustic comfort for the patient during therapy.

The antimicrobial filter 17 on the second conduit 14 is located downstream of the exhaled gas outlet 13 and upstream of the possible PEEP valve 15, to also protect the patient's expiration.

In figures 2A, 2B and 2C, 2D, the respective graphs or diagrams of the performance of the equipment 1 are represented when the regulation parameters vary, in particular the oxygen value. These are graphs shown by way of example and to better understand the possible regulation for the patient by means of the equipment 1. Inside these graphs, the flow of the second flow meter 7 remains equal to 0 l/min.

Therefore, these figures show how the mixture curve varies depending on the oxygen value and how the consequent resulting FiO2 curve evolves.

It is necessary to emphasize how the scale used on the ordinate axes is greatly amplified so that the evolution of the curve can be observed more clearly. Consequently, these curves are advantageously very flat, also guaranteeing minimal titration variations.

Figure 3 shows a second embodiment of a flow generation equipment 101 for non-invasive ventilation according to the invention, called "single flowmeter".

The present second embodiment differs from the first embodiment by the presence of a single first flowmeter 105 instead of the first flowmeter 5 and the second flowmeter 7.

The rest of the elements are analogous for the two embodiments and the same reference numbers will therefore be used for them.

Always present, in particular, is the air inlet 3, which comprises the narrowing element 3A.

Precisely by utilizing this feature it is, in fact, possible to apply the same equipment both in a "double flow meter" case like the one in the first embodiment, and in a "single flow meter" case like the one described here. .

In fact, thanks to the possibility of dosing the incoming air by means of the narrowing element 3A, it is possible to regulate the inspired fraction FiO2 accordingly.

The first flowmeter 105 is a high flow oxygen flowmeter. For example, it is possible to use a flowmeter capable of managing flows of at least 15 l/min and at double scale, that is, 2-10 l/min and 6-50 l/min.

Venturi device 2 is connected to the outlet of the first high flow variable area oxygen flowmeter 105.

Also in this case, the first flow meter 105 serves as a "driver" source for the Venturi device 2.

In this embodiment, therefore, to obtain the correct oxygen titration, instead of having an additional introduction of oxygen, there is a reduction in the ambient air sucked in.

Also in the present embodiment, an oximeter 16 is provided, connected in line with the Venturi device 2, arranged opposite the first flowmeter 105, which makes it possible to constantly monitor the concentration of oxygen present in the mixture supplied to the patient.

Still further, also in the present second embodiment, an antimicrobial filter 17 is connected, which can be located either on the first conduit 10 or on the second conduit 14.

The antimicrobial filter 17, when it is located on the first duct 10, apart from guaranteeing protection for the patient, makes it possible to attenuate the noise generated by the flow of the mixture, thus also obtaining greater acoustic comfort for the patient during therapy.

Figures 4A, 4B, 4C, 4D, 4E show, also in this case, respective graphs or diagrams of the performance of the equipment 101 by varying the regulation parameters, in particular the oxygen value.

These graphs are shown only as an example and to better understand the regulation possible for the patient through the 101 equipment.

Among the different graphs, the variable parameter is the position of the narrowing element 3A.

Figure 5 also represents a variant 101' of the equipment 101 of the second embodiment described above, this variant being intended in particular for precarious clinical conditions that require an oxygen titration of the order of 70% or higher, and specifically up to The 100 %.

This variant 101' also provides for the presence of a flow selection element 106 that allows the first flow meter 105 to be put directly into functional connection with the first conduit 10, without passing through the Venturi device 2.

The flow selection element 106 is represented by an alternative conduit that opens at the same time as the closure of the passage between the first flow meter 105 and the Venturi mask 2, at the time of a request for titration mentioned above.

This solution is due to an intrinsic technical limitation in the use of the Venturi device in the presence of a single flowmeter.

In fact, if an FiO2 of the order of 70% or higher is requested, and specifically up to 100%, in the presence of a single flowmeter, the total flow opening of the flowmeter 105 and the closing of the narrowing element 3A is not sufficient, since the internal injector to the Venturi 2 device would in any case limit the arrival of pure oxygen. Therefore, the only way for this extreme case is to avoid the Venturi device 2 by creating an alternative circuit.

This type of mode, defined as "flush", makes it possible to feed the system with flows of up to 70 l/min of pure oxygen.

According to a third embodiment, visible in particular in Figure 6, the present invention provides a flow generation equipment 201 for non-invasive ventilation, additionally an integrated structure 202.

The rest of the elements are analogous for the two embodiments and, therefore, the same reference numbers will be used.

A "single flowmeter" solution is presented in this document. Nothing will prevent further developments from envisioning an integrated "double flowmeter”.

The integrated structure 202 comprises a first flowmeter 203, which generates a drag flow that determines the mixture of air and oxygen; for example, it is possible to use a high flow oxygen flow meter to deliver flow rates of at least 50 l/min and dual scaled, i.e. 2-10 l/min and 6-50 l/min.

Furthermore, the first flowmeter 203 is integrated in a Venturi device 204. It is therefore possible, with a single device, to use it in CPAP therapy and high-flow oxygen therapy (HFNC).

Also according to the present embodiment, the Venturi device 203 functions as a flow generator and amplifier and requires only feeding from an oxygen source.

Also in this case, the narrowing element 3A is always present, thanks to which it is possible to regulate the air sucked in from the room and therefore the inspired fraction FiO2.

In the integrated structure there is therefore also a manual regulator 206 for regulating the flow from the first flow meter 203.

The integrated structure 202 also provides a hook clamp 204 for a secure connection.

At the inlet of the integrated structure 202, a specific gas threaded connection is preferably provided for connection to the oxygen source by means of a flexible tube (not shown), the latter provided with an appropriate gear in the user's distribution installation and fixed immovable.

Also in the present embodiment, an oximeter 205 is provided, also integrated in the integrated structure 20 and in line with the first flowmeter 204, which makes it possible to constantly monitor the concentration of oxygen present in the mixture supplied to the patient.

Still further, also in the present second embodiment, an antimicrobial filter 17 is connected which can be placed either on the first conduit 10 or on the second conduit 14.

The antimicrobial filter 17, when placed on the first duct 10, apart from guaranteeing protection for the patient, makes it possible to attenuate the noise generated by the flow of the mixture, thus also obtaining greater acoustic comfort for the patient during therapy.

According to a different aspect, the present invention provides a flow management system 1000 for equipment for non-invasive ventilation comprising equipment 1, 101, 101', 201 according to one of the embodiments described above.

Specifically, in figure 7 a system 1000 is represented that includes a piece of equipment 201, but nothing prevents using one of the other embodiments described.

The system 1000 further comprises at least one carbon dioxide absorber 1001, a recirculation circuit 1002 comprising at least one suction and purge line 1003 upstream of this carbon dioxide absorber 1001.

The recirculation circuit 1002 is configured to recover at least part of the mixture exhaled by the patient.

The suction and purge line 1003 is configured to avoid under or over pressures inside the system 1001.

In addition, in the event that there is a depression inside the recirculation circuit 1002 and, therefore, an insufficient amount of mixture in the recirculation circuit 1002, it can be mitigated from a suction directly from the outside through the suction duct and purge 1003.

Therefore, this suction and purge duct 1003 has a double function depending on the direction imposed by the pressure conditions between the inside and the outside of the recirculation circuit 1002 itself.

In other words, if there is a higher pressure inside the system with respect to external conditions, there is a purge function, while if there is a depression inside the system 1000 with respect to external conditions. external, there is a suction function that is going to perform a kind of compensation inside the system 1000.

The carbon dioxide absorber 1002 can provide a soda lime element, a solid amine element or other solutions such as so-called "electroswing" batteries.

Advantageously, the present invention makes it possible to optimize the advantages of using both CPAP-type therapy and high-flow oxygen therapy (HFNC), while mitigating the drawbacks still present in prior art devices.

Advantageously, the equipment according to the invention makes it possible to use it in solutions that comprise one or two flow meters, without structural variations of the same, but simply by means of a different type of regulation.

In other words, the equipment according to the invention can be used in a non-invasive ventilation system that provides for the use of two flowmeters, obtaining the desired titration by means of an additional oxygen supply, and in a non-invasive ventilation system that provides for the use of a single flowmeter regulating the arrival of air through the narrowing element.

The equipment according to the invention has its main fields of use in:

• treatment of ARDS (acute respiratory distress syndrome);

• acute respiratory failure;

• postoperative hypoxemia;

• flare-ups of COPD (chronic obstructive pulmonary disease);

• pulmonary contusions from chest trauma;

• pulmonary edema

• atelectasis of various origins,

• after removing the mechanical ventilator.

In addition, the present solution makes it possible to obtain an optimal mixture generation and dosage for a patient with a correct regulation of the oxygen titration value of said gas mixture.

Furthermore, a person skilled in the art will appreciate how the present invention is specific to CPAP therapy and high-flow oxygen therapy, but applicable, in any case, to different types of pre-existing systems and circuits within the scope of a therapy of this type. type to extol the overall performance.

Finally, still advantageously, the present solution is the result of a simple implementation from a production point of view.

The person skilled in the art will understand that the presented embodiment may be subject to additional modifications and variations, according to specific and contingent requirements, all falling within the scope of protection of the invention, as defined by the following claims.

Claims (13)

1. Flow generation equipment (1, 101, 101', 201) for non-invasive ventilation or high-flow oxygen therapy comprising: - at least one Venturi device (2, 204) to supply a gas mixture; - at least one air inlet (3) in said Venturi device, comprising at least one constriction element (3A) to dose the amount of air sucked into said Venturi device (2, 204); - an interface element (12) that completely or partially covers the patient's respiratory tract and that comprises an inlet port for the fresh gas mixture (11); - a first conduit (10) for functionally connecting said Venturi device (2, 204) with said interface element (12); - at least one first flowmeter (5, 105, 203), associated with said Venturi device (2, 204) by means of at least one supply connection (4) and suitable for dosing said gas mixture. 2. Flow generation equipment (1, 101, 101', 201) for non-invasive ventilation or high-flow oxygen therapy according to claim 1, further comprising an outlet for excess gas and patient expiration ( 13) and a second conduit (14) to evacuate from said interface element (12) the gases exhaled by the patient through said outlet (13). 3. Flow generation equipment (1, 101, 101', 201) for non-invasive ventilation or high-flow oxygen therapy according to claim 2, further comprising a positive pressure maintenance valve (15) associated with said mouth outlet (13). 4. Flow generation equipment (1, 101, 101', 201) for non-invasive ventilation or high-flow oxygen therapy according to any one of claims 1 to 3, wherein said at least one first flow meter (5 , 105, 203) is a high-flow flowmeter capable of reaching flow rates of at least 15 l/min. 5. Flow generation equipment (1) for non-invasive ventilation or high-flow oxygen therapy according to any one of claims 1 to 4, further comprising a second flowmeter (7) to regulate the titration value in said mixture of gases, comprising a flexible fitting (6) that can be associated with at least one Venturi device (2). 6. Flow generation equipment (1) for non-invasive ventilation or high-flow oxygen therapy according to claim 5, wherein said second flowmeter (7) is a high-flow flowmeter capable of reaching flows of at least 15 l/min. . 7. Flow generation equipment (101') for non-invasive ventilation or high-flow oxygen therapy according to any one of claims 1 to 4, further comprising at least one flow selection element to regulate the value of the oxygen titration of said gas mixture in the presence of requests for titration greater than 70% and up to 100%. 8. Flow generation equipment (201) for non-invasive ventilation or high-flow oxygen therapy according to claim 1, wherein said first flowmeter (203) is integrated in said Venturi device (204) and generates a drag flow that determines the mixture of air and oxygen. 9. Flow generation equipment (1, 101, 101', 201) for non-invasive ventilation or high-flow oxygen therapy according to any one of claims 1 to 8, further comprising an oximeter (16, 205 ) connected in line with said Venturi device (2, 204) and suitable for measuring and monitoring the degree of oxygen titration in said gas mixture. 10. Flow generation equipment (1, 101, 101', 201) for non-invasive ventilation or high-flow oxygen therapy according to any one of claims 1 to 9, further comprising at least one antimicrobial filter ( 17) to protect the patient, also suitable to attenuate the noise of said equipment. 11. Flow generation equipment (1, 101, 101', 201) for non-invasive ventilation or high-flow oxygen therapy according to any one of claims 1 to 10, wherein said at least one interface element ( 12) with the respiratory tract of a patient comprises a nasal mask, an oronasal mask or a helmet for CPAP therapy. 12. Flow generation equipment (1, 101, 101', 201) for non-invasive ventilation or high-flow oxygen therapy according to any one of claims 1 to 10, wherein said at least one interface element ( 12) with a patient's airway consists of a HFNC high-flow nasal cannula. 13. Flow management system (1000) for a device for non-invasive ventilation or high-flow oxygen therapy, comprising: - at least one carbon dioxide absorber (1001); - a recirculation circuit (1002), comprising at least one suction and purge conduit (1003) upstream of said carbon dioxide absorber (1001); - a flow generation equipment (1, 101, 101', 201) according to any one of the preceding claims from 1 to 12.