EP4698641A1 - Neue rekombinaseenzyme zur stellenspezifischen dna-rekombination - Google Patents

Neue rekombinaseenzyme zur stellenspezifischen dna-rekombination

Info

Publication number
EP4698641A1
EP4698641A1 EP24720781.4A EP24720781A EP4698641A1 EP 4698641 A1 EP4698641 A1 EP 4698641A1 EP 24720781 A EP24720781 A EP 24720781A EP 4698641 A1 EP4698641 A1 EP 4698641A1
Authority
EP
European Patent Office
Prior art keywords
seq
acid sequence
nucleic acid
protein
identity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP24720781.4A
Other languages
English (en)
French (fr)
Inventor
Milica JELICIC
Lukas Theo Schmitt
Frank Buchholz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Technische Universitaet Dresden
Original Assignee
Technische Universitaet Dresden
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Technische Universitaet Dresden filed Critical Technische Universitaet Dresden
Publication of EP4698641A1 publication Critical patent/EP4698641A1/de
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/102—Mutagenizing nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/22—Ribonucleases [RNase]; Deoxyribonucleases [DNase]

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
EP24720781.4A 2023-04-17 2024-04-17 Neue rekombinaseenzyme zur stellenspezifischen dna-rekombination Pending EP4698641A1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP23168351 2023-04-17
PCT/EP2024/060392 WO2024218137A1 (en) 2023-04-17 2024-04-17 Novel recombinase enzymes for site-specific dna-recombination

Publications (1)

Publication Number Publication Date
EP4698641A1 true EP4698641A1 (de) 2026-02-25

Family

ID=86053682

Family Applications (1)

Application Number Title Priority Date Filing Date
EP24720781.4A Pending EP4698641A1 (de) 2023-04-17 2024-04-17 Neue rekombinaseenzyme zur stellenspezifischen dna-rekombination

Country Status (4)

Country Link
EP (1) EP4698641A1 (de)
CN (1) CN121263522A (de)
TW (1) TW202507002A (de)
WO (1) WO2024218137A1 (de)

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7422889B2 (en) 2004-10-29 2008-09-09 Stowers Institute For Medical Research Dre recombinase and recombinase systems employing Dre recombinase
DE102007001370A1 (de) 2007-01-09 2008-07-10 Curevac Gmbh RNA-kodierte Antikörper
WO2010143606A1 (ja) 2009-06-08 2010-12-16 財団法人かずさディー・エヌ・エー研究所 新規な部位特異的組換え酵素とその認識配列を用いた部位特異的組換え方法
US11291635B2 (en) 2010-07-06 2022-04-05 Glaxosmithkline Biological Sa Virion-like delivery particles for self-replicating RNA molecules
EP2690177B1 (de) 2012-07-24 2014-12-03 Technische Universität Dresden Protein mit Rekombinase-Aktivität zur ortspezifischen DNA-Rekombination
CA3147875A1 (en) * 2019-07-19 2021-01-28 Flagship Pioneering Innovations Vi, Llc Recombinase compositions and methods of use

Also Published As

Publication number Publication date
TW202507002A (zh) 2025-02-16
CN121263522A (zh) 2026-01-02
WO2024218137A1 (en) 2024-10-24

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