EP4669762A2 - Verfahren und zusammensetzungen zur herstellung und reinigung von peptiden - Google Patents

Verfahren und zusammensetzungen zur herstellung und reinigung von peptiden

Info

Publication number
EP4669762A2
EP4669762A2 EP24707503.9A EP24707503A EP4669762A2 EP 4669762 A2 EP4669762 A2 EP 4669762A2 EP 24707503 A EP24707503 A EP 24707503A EP 4669762 A2 EP4669762 A2 EP 4669762A2
Authority
EP
European Patent Office
Prior art keywords
oligopeptides
polypeptide
amino acids
acids long
sequence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP24707503.9A
Other languages
English (en)
French (fr)
Inventor
Orso SUBRINI
Renaud CARTIER
Mikaël Stéphane COURBOT
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Micropep Technologies SA
Original Assignee
Micropep Technologies SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Micropep Technologies SA filed Critical Micropep Technologies SA
Publication of EP4669762A2 publication Critical patent/EP4669762A2/de
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/02—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing liquids as carriers, diluents or solvents
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
    • A01N37/44—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a nitrogen atom attached to the same carbon skeleton by a single or double bond, this nitrogen atom not being a member of a derivative or of a thio analogue of a carboxylic group, e.g. amino-carboxylic acids
    • A01N37/46—N-acyl derivatives
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01P—BIOCIDAL, PEST REPELLANT, PEST ATTRACTANT OR PLANT GROWTH REGULATORY ACTIVITY OF CHEMICAL COMPOUNDS OR PREPARATIONS
    • A01P15/00—Biocides for specific purposes not provided for in groups A01P1/00 - A01P13/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
    • C12N15/8271—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
    • C12N15/8279—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y406/00—Phosphorus-oxygen lyases (4.6)
    • C12Y406/01—Phosphorus-oxygen lyases (4.6.1)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/09—Fusion polypeptide containing a localisation/targetting motif containing a nuclear localisation signal
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/10—Fusion polypeptide containing a localisation/targetting motif containing a tag for extracellular membrane crossing, e.g. TAT or VP22
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A40/00—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
    • Y02A40/10—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in agriculture
    • Y02A40/146—Genetically Modified [GMO] plants, e.g. transgenic plants

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Plant Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Environmental Sciences (AREA)
  • Pest Control & Pesticides (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dentistry (AREA)
  • Agronomy & Crop Science (AREA)
  • Botany (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
EP24707503.9A 2023-02-23 2024-02-23 Verfahren und zusammensetzungen zur herstellung und reinigung von peptiden Pending EP4669762A2 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US202363486652P 2023-02-23 2023-02-23
US202363486653P 2023-02-23 2023-02-23
US202363486654P 2023-02-23 2023-02-23
PCT/EP2024/054685 WO2024175788A2 (en) 2023-02-23 2024-02-23 Methods and compositions for production and purification of peptides

Publications (1)

Publication Number Publication Date
EP4669762A2 true EP4669762A2 (de) 2025-12-31

Family

ID=90057228

Family Applications (3)

Application Number Title Priority Date Filing Date
EP24707503.9A Pending EP4669762A2 (de) 2023-02-23 2024-02-23 Verfahren und zusammensetzungen zur herstellung und reinigung von peptiden
EP24707494.1A Pending EP4669655A2 (de) 2023-02-23 2024-02-23 Antifungale peptide zur bekämpfung von pflanzenpathogenen
EP24707495.8A Pending EP4669656A1 (de) 2023-02-23 2024-02-23 Mikropeptide zur verbesserung der pflanzenimmunität und anwendung davon

Family Applications After (2)

Application Number Title Priority Date Filing Date
EP24707494.1A Pending EP4669655A2 (de) 2023-02-23 2024-02-23 Antifungale peptide zur bekämpfung von pflanzenpathogenen
EP24707495.8A Pending EP4669656A1 (de) 2023-02-23 2024-02-23 Mikropeptide zur verbesserung der pflanzenimmunität und anwendung davon

Country Status (8)

Country Link
EP (3) EP4669762A2 (de)
KR (1) KR20250154428A (de)
CN (2) CN120958034A (de)
AU (2) AU2024225703A1 (de)
CO (1) CO2025011232A2 (de)
IL (2) IL322884A (de)
MX (1) MX2025009720A (de)
WO (3) WO2024175788A2 (de)

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4342832A (en) 1979-07-05 1982-08-03 Genentech, Inc. Method of constructing a replicable cloning vehicle having quasi-synthetic genes
ZA811368B (en) 1980-03-24 1982-04-28 Genentech Inc Bacterial polypedtide expression employing tryptophan promoter-operator
EP0316018A3 (de) 1985-03-29 1989-07-26 Cetus Oncology Corporation Modifikation von DNS-Sequenzen
AU3869289A (en) 1988-07-14 1990-02-05 Baylor College Of Medicine Solid phase assembly and reconstruction of biopolymers
EP0385410B1 (de) 1989-02-28 1996-10-02 Canon Kabushiki Kaisha Partiell doppelsträngiges Oligonukleotid und Verfahren zu seiner Bildung
AU648140B2 (en) * 1991-02-01 1994-04-14 Virtual Drug Development, Inc. Reverse antimicrobial peptides and antimicrobial compositions
WO1994012632A1 (en) 1992-11-27 1994-06-09 University College London Improvements in nucleic acid synthesis by pcr
DE4343591A1 (de) 1993-12-21 1995-06-22 Evotec Biosystems Gmbh Verfahren zum evolutiven Design und Synthese funktionaler Polymere auf der Basis von Formenelementen und Formencodes
EP0796335A1 (de) * 1994-12-07 1997-09-24 Bionebraska, Inc. Herstellung von peptiden mittles rekombinanter fusionsprotein-konstruktionen
AUPN283495A0 (en) 1995-05-05 1995-06-01 Australian National University, The Plant promoter activated by fungal infection
ATE462004T1 (de) 1997-09-16 2010-04-15 Centocor Inc Methoden zur kompletten chemischen synthese und zusammensetzung von genen und genomen
DE59912120D1 (de) 1998-08-28 2005-07-07 Febit Ag Träger für analytbestimmungsverfahren und verfahren zur herstellung des trägers
DE50013228D1 (de) 1999-02-19 2006-09-07 Febit Biotech Gmbh Verfahren zur herstellung von polymeren
CA2482995C (en) * 2002-04-22 2013-01-29 Dow Global Technologies Inc. Low-cost production of peptides
PL2061886T3 (pl) * 2006-08-21 2014-10-31 Univ British Columbia Małe kationowe peptydy immunomodulujące
WO2011084061A1 (en) 2010-01-08 2011-07-14 Universitair Medisch Centrum St. Radboud Cpp (cell penetrating peptide) and its uses
WO2011126644A2 (en) 2010-03-31 2011-10-13 Dow Agrosciences Llc Plant peptide gamma-zein for delivery of biomolecules into plant cells
TR201905612T4 (tr) 2012-12-05 2019-05-21 Univ Heidelberg Ruprecht Karls Proteinlerin ve çok değerlikli, hücreye nüfuz eden peptitlerin konjugatları ve bunların kullanımları.
JP6574175B2 (ja) 2013-07-12 2019-09-11 ジェムバックス アンド カエル カンパニー，リミティド 細胞透過性ペプチド、及びそれを含むコンジュゲート
KR101841211B1 (ko) 2014-03-10 2018-03-22 한양대학교 산학협력단 세포 투과성 펩티드 및 이를 이용한 생물학적 활성 물질의 전달방법
CA2951018C (fr) * 2014-06-03 2023-11-14 Universite Toulouse Iii-Paul Sabatier Utilisation de micropeptides pour favoriser la symbiose mycorhizienne
AU2018304469B2 (en) * 2017-07-20 2023-04-06 Spogen Biotech Inc. Bioactive polypeptides for improvements in plant protection, growth and productivity
EP3694308A1 (de) 2017-10-13 2020-08-19 Pioneer Hi-Bred International, Inc. Systeme und verfahren zur zellulären neuprogrammierung einer pflanzenzelle
EP3720271A1 (de) 2017-12-04 2020-10-14 University of Florida Research Foundation Genomeditierung durch pollenvermittelte transformation
BR112021003380A2 (pt) 2018-08-28 2021-05-18 Flagship Pioneering Innovations Vi, Llc métodos e composições para modulação de um genoma

Also Published As

Publication number Publication date
KR20250154428A (ko) 2025-10-28
WO2024175788A3 (en) 2024-12-12
WO2024175778A3 (en) 2024-10-17
MX2025009720A (es) 2026-01-07
CO2025011232A2 (es) 2026-01-13
AU2024225703A1 (en) 2025-08-14
WO2024175780A1 (en) 2024-08-29
IL322882A (en) 2025-10-01
WO2024175778A2 (en) 2024-08-29
EP4669656A1 (de) 2025-12-31
WO2024175788A2 (en) 2024-08-29
AU2024226512A1 (en) 2025-08-14
EP4669655A2 (de) 2025-12-31
CN120958034A (zh) 2025-11-14
IL322884A (en) 2025-10-01
CN120882737A (zh) 2025-10-31

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