EP4408223A1 - Appareil de substitution pour fumeur - Google Patents

Appareil de substitution pour fumeur

Info

Publication number
EP4408223A1
EP4408223A1 EP22783450.4A EP22783450A EP4408223A1 EP 4408223 A1 EP4408223 A1 EP 4408223A1 EP 22783450 A EP22783450 A EP 22783450A EP 4408223 A1 EP4408223 A1 EP 4408223A1
Authority
EP
European Patent Office
Prior art keywords
aerosol
air flow
air
inhale
particle size
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP22783450.4A
Other languages
German (de)
English (en)
Inventor
Phillip Taylor
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Imperial Tobacco Ltd
Original Assignee
Imperial Tobacco Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Imperial Tobacco Ltd filed Critical Imperial Tobacco Ltd
Publication of EP4408223A1 publication Critical patent/EP4408223A1/fr
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24F—SMOKERS' REQUISITES; MATCH BOXES; SIMULATED SMOKING DEVICES
    • A24F40/00—Electrically operated smoking devices; Component parts thereof; Manufacture thereof; Maintenance or testing thereof; Charging means specially adapted therefor
    • A24F40/40—Constructional details, e.g. connection of cartridges and battery parts
    • A24F40/48—Fluid transfer means, e.g. pumps
    • A24F40/485—Valves; Apertures
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24F—SMOKERS' REQUISITES; MATCH BOXES; SIMULATED SMOKING DEVICES
    • A24F40/00—Electrically operated smoking devices; Component parts thereof; Manufacture thereof; Maintenance or testing thereof; Charging means specially adapted therefor
    • A24F40/10—Devices using liquid inhalable precursors

Definitions

  • the present invention relates to a smoking substitute apparatus and, in particular, a smoking substitute apparatus that is able to deliver nicotine to a user in an effective manner.
  • the smoking of tobacco is generally considered to expose a smoker to potentially harmful substances. It is thought that a significant amount of the potentially harmful substances are generated through the burning and/or combustion of the tobacco and the constituents of the burnt tobacco in the tobacco smoke itself.
  • Such smoking substitute systems can form part of nicotine replacement therapies aimed at people who wish to stop smoking and overcome a dependence on nicotine.
  • Known smoking substitute systems include electronic systems that permit a user to simulate the act of smoking by producing an aerosol (also referred to as a “vapour”) that is drawn into the lungs through the mouth (inhaled) and then exhaled.
  • the inhaled aerosol typically bears nicotine and/or a flavourant without, or with fewer of, the health risks associated with conventional smoking.
  • smoking substitute systems are intended to provide a substitute for the rituals of smoking, whilst providing the user with a similar, or improved, experience and satisfaction to those experienced with conventional smoking and with combustible tobacco products.
  • smoking substitute systems have grown rapidly in the past few years as an aid to assist habitual smokers wishing to quit tobacco smoking.
  • Some smoking substitute systems are designed to resemble a conventional cigarette and are cylindrical in form with a mouthpiece at one end.
  • Other smoking substitute devices do not generally resemble a cigarette (for example, the smoking substitute device may have a generally box-like form, in whole or in part).
  • vaping in which a vaporisable liquid, or an aerosol former, sometimes typically referred to herein as “e-liquid”, is heated by a heating device (sometimes referred to herein as an electronic cigarette or “e-cigarette” device) to produce an aerosol vapour which is inhaled by a user.
  • e-liquid typically includes a base liquid, nicotine and may include a flavourant.
  • the resulting vapour therefore also typically contains nicotine and/or a flavourant.
  • the base liquid may include propylene glycol and/or vegetable glycerine.
  • a typical e-cigarette device includes a mouthpiece, a power source (typically a battery), a tank for containing e-liquid and a heating device.
  • a power source typically a battery
  • a tank for containing e-liquid In use, electrical energy is supplied from the power source to the heating device, which heats the e-liquid to produce an aerosol (or “vapour”) which is inhaled by a user through the mouthpiece.
  • E-cigarettes can be configured in a variety of ways.
  • “closed system” vaping smoking substitute systems typically have a sealed tank and heating element. The tank is prefilled with e-liquid and is not intended to be refilled by an end user.
  • One subset of closed system vaping smoking substitute systems include a main body which includes the power source, wherein the main body is configured to be physically and electrically couplable to a consumable including the tank and the heating element. In this way, when the tank of a consumable has been emptied of e-liquid, that consumable is removed from the main body and disposed of. The main body can then be reused by connecting it to a new, replacement, consumable.
  • Another subset of closed system vaping smoking substitute systems are completely disposable, and intended for one-use only.
  • vaping smoking substitute systems typically have a tank that is configured to be refilled by a user. In this way the entire device can be used multiple times.
  • An example vaping smoking substitute system is the mybluTM e-cigarette.
  • the mybluTM e-cigarette is a closed system which includes a main body and a consumable.
  • the main body and consumable are physically and electrically coupled together by pushing the consumable into the main body.
  • the main body includes a rechargeable battery.
  • the consumable includes a mouthpiece and a sealed tank which contains e-liquid.
  • the consumable further includes a heater, which for this device is a heating filament coiled around a portion of a wick. The wick is partially immersed in the e-liquid, and conveys e-liquid from the tank to the heating filament.
  • the system is controlled by a microprocessor on board the main body.
  • the system includes a sensor for detecting when a user is inhaling through the mouthpiece, the microprocessor then activating the device in response.
  • the system When the system is activated, electrical energy is supplied from the power source to the heating device, which heats e-liquid from the tank to produce a vapour which is inhaled by a user through the mouthpiece.
  • the aerosol droplets have a size distribution that is not suitable for delivering nicotine to the lungs. Aerosol droplets of a large particle size tend to be deposited in the mouth and/or upper respiratory tract. Aerosol particles of a small (e.g. sub-micron) particle size can be inhaled into the lungs but may be exhaled without delivering nicotine to the lungs. As a result the user would require drawing a longer puff, more puffs, or vaporising e-liquid with a higher nicotine concentration in order to achieve the desired experience.
  • the present invention provides an air flow disruptor located at a position in the air flow path at which the particle size characteristics of the aerosol are settled, the air flow disruptor causing disruption of the air flow downstream of the air flow disruptor and consequently cooling the aerosol droplets without substantially changing the aerosol particle size characteristics.
  • a method of operating a smoking substitute apparatus comprising: an air inlet; an aerosol generator for generating an aerosol from an aerosol precursor for inhalation by a user; an outlet formed at a mouthpiece; at least one air flow path between the air inlet and the outlet for conveying the aerosol to the user; the method including the steps: operating the aerosol generator to heat the aerosol precursor to form vaporised aerosol precursor, the vaporised aerosol precursor being transported in the air flow and condensing to form aerosol droplets, wherein the air flow path and the aerosol generator are configured to control the air flow characteristics at the aerosol generator to provide an aerosol with predetermined particle size characteristics at a first position in the air flow path downstream of the aerosol generator, the average temperature of the aerosol droplets at the first position being at least 70°C, the apparatus further comprising an air flow disruptor disposed in the air flow path at or downstream of the first position, the air flow disruptor causing disruption of the air flow downstream of the air flow
  • a smoking substitute apparatus comprising: an air inlet; an aerosol generator for generating an aerosol from an aerosol precursor for inhalation by a user; an outlet formed at a mouthpiece; at least one air flow path between the air inlet and the outlet for conveying the aerosol to the user; wherein, in operation, the aerosol generator heats the aerosol precursor to form vaporised aerosol precursor, the vaporised aerosol precursor being transported in the air flow and condensing to form aerosol droplets, wherein the air flow path and the aerosol generator are configured to control the air flow characteristics at the aerosol generator to provide an aerosol with predetermined particle size characteristics at a first position in the air flow path downstream of the aerosol generator, the average temperature of the aerosol droplets at the first position being at least 70°C, the apparatus further comprising an air flow disruptor disposed in the air flow path at or downstream of the first position, the air flow disruptor causing disruption of the air flow downstream of the air flow disruptor and consequently cooling of the aerosol
  • a smoking substitute apparatus comprising: an air inlet; an aerosol generator for generating an aerosol from an aerosol precursor for inhalation by a user; an outlet formed at a mouthpiece; an aerosol delivery conduit extending downstream from the aerosol generator to the outlet; at least one air flow path between the air inlet and the outlet and along the aerosol delivery conduit for conveying the aerosol to the user; wherein, in operation, the aerosol generator heats the aerosol precursor to form vaporised aerosol precursor, the vaporised aerosol precursor being transported in the air flow and condensing to form aerosol droplets, wherein the air flow path and the aerosol generator are configured to control the air flow characteristics at the aerosol generator to provide an aerosol with predetermined particle size characteristics at a first position along the air flow path in the aerosol delivery conduit, the apparatus further comprising an air flow disruptor disposed in the aerosol delivery conduit at or downstream of the first position, the air flow disruptor causing disruption of the air flow downstream of the air flow disruptor and consequently
  • the smoking substitute apparatus may be comprised by or within a cartridge configured for engagement with the main body, the cartridge and main body together forming a smoking substitute system.
  • the smoking substitute apparatus may be removably engageable with the main body (which may also be referred to herein as the base unit).
  • the smoking substitute apparatus may be in the form of a consumable.
  • the consumable may be configured for engagement with a main body.
  • the combination of the consumable and the main body may form a smoking substitute system such as a closed smoking substitute system.
  • the consumable may comprise components of the system that are disposable, and the main body may comprise non-disposable or non-consumable components (e.g. power supply, controller, sensor, etc.) that facilitate the generation and/or delivery of aerosol by the consumable.
  • the aerosol precursor e.g. e-liquid
  • the smoking substitute apparatus may be a non-consumable apparatus (e.g. that is in the form of an open smoking substitute system).
  • an aerosol former e.g. e-liquid
  • the aerosol precursor may be replenished by re-filling, e.g. a reservoir of the smoking substitute apparatus, with the aerosol precursor (rather than replacing a consumable component of the apparatus).
  • the smoking substitute apparatus may alternatively form part of a main body for engagement with the smoking substitute apparatus. This may be the case in particular when the smoking substitute apparatus is in the form of a consumable.
  • the main body and the consumable may be configured to be physically coupled together.
  • the consumable may be at least partially received in a recess of the main body, such that there is an interference fit between the main body and the consumable.
  • the main body and the consumable may be physically coupled together by screwing one onto the other, or through a bayonet fitting, or the like.
  • the smoking substitute apparatus may comprise one or more engagement portions for engaging with a main body.
  • one end of the smoking substitute apparatus may be coupled with the main body, whilst an opposing end of the smoking substitute apparatus may define a mouthpiece of the smoking substitute system.
  • the smoking substitute apparatus may comprise a reservoir configured to store an aerosol precursor, such as an e-liquid.
  • the e-liquid may, for example, comprise a base liquid.
  • the e-liquid may further comprise nicotine.
  • the base liquid may include propylene glycol and/or vegetable glycerine.
  • the e-liquid may be substantially flavourless. That is, the e-liquid may not contain any deliberately added additional flavourant and may consist solely of a base liquid of propylene glycol and/or vegetable glycerine and nicotine.
  • the reservoir may be in the form of a tank. At least a portion of the tank may be light-transmissive.
  • the tank may comprise a window to allow a user to visually assess the quantity of e-liquid in the tank.
  • a housing of the smoking substitute apparatus may comprise a corresponding aperture (or slot) or window that may be aligned with a light-transmissive portion (e.g. window) of the tank.
  • the reservoir may be referred to as a “clearomizer” if it includes a window, or a “cartomizer” if it does not.
  • the outlet may be at a mouthpiece of the smoking substitute apparatus.
  • a user may draw fluid (e.g. air) into and through the passage by inhaling at the outlet (i.e. using the mouthpiece).
  • the passage may be at least partially defined by the tank.
  • the tank may substantially (or fully) define the passage, for at least a part of the length of the passage.
  • the tank may surround the passage, e.g. in an annular arrangement around the passage.
  • the vaporisation chamber may be arranged to be in fluid communication with the inlet and outlet of the passage.
  • the vaporisation chamber may be an enlarged portion of the passage.
  • the air as drawn in by the user may entrain the generated vapour in a flow away from heater.
  • the entrained vapour may form an aerosol in the vaporisation chamber, or it may form the aerosol further downstream along the passage.
  • the vaporisation chamber may be at least partially defined by the tank.
  • the tank may substantially (or fully) define the vaporisation chamber, and thus may form the enclosure. In this respect, the tank may surround the vaporisation chamber, e.g. in an annular arrangement around the vaporisation chamber.
  • the user may puff on a mouthpiece of the smoking substitute apparatus, i.e. draw on the smoking substitute apparatus by inhaling, to draw in an air stream therethrough.
  • the part of the air flow which bypasses the vaporisation chamber may combine with the other part of the air flow (main air flow) for diluting the aerosol contained therein.
  • the dilution air flow may be directly inhaled by the user without passing through the passage of the smoking substitute apparatus.
  • vaporised e-liquid entrained in the passing air flow may be drawn towards the outlet of the passage.
  • the vapour may cool, and thereby nucleate and/or condense along the passage to form a plurality of aerosol droplets, e.g. nicotine-containing aerosol droplets.
  • a portion of these aerosol droplets may be delivered to and be absorbed at a target delivery site, e.g. a user’s lung, whilst a portion of the aerosol droplets may instead adhere onto other parts of the user’s respiratory tract, e.g. the user’s oral cavity and/or throat.
  • the aerosol droplets as measured at the outlet of the passage e.g. at the mouthpiece, may have a droplet size, dso, of less than 1 pm.
  • the dso particle size of the aerosol particles is preferably at least 1 pm, more preferably at least 2 pm.
  • the dso particle size is not more than 10 pm, preferably not more than 9 pm, not more than 8 pm, not more than 7 pm, not more than 6 pm, not more than 5 pm, not more than 4 irn or not more than 3 pirn. It is considered that providing aerosol particle sizes in such ranges permits improved interaction between the aerosol particles and the user’s lungs.
  • the particle droplet size, dso, of an aerosol may be measured by a laser diffraction technique.
  • the stream of aerosol output from the outlet of the passage may be drawn through a Malvern Spraytec laser diffraction system, where the intensity and pattern of scattered laser light are analysed to calculate the size and size distribution of aerosol droplets.
  • the particle size distribution may be expressed in terms of dio, dso and dgo, for example.
  • the d particle size is the particle size below which 10% by volume of the sample lies.
  • the dso particle size is the particle size below which 50% by volume of the sample lies.
  • the dgo particle size is the particle size below which 90% by volume of the sample lies.
  • the particle size measurements are volume-based particle size measurements, rather than number-based or mass-based particle size measurements.
  • the spread of particle size may be expressed in terms of the span, which is defined as (dgo-dio)/dso.
  • the span is not more than 20, preferably not more than 10, preferably not more than 8, preferably not more than 4, preferably not more than 2, preferably not more than 1 , or not more than 0.5.
  • the smoking substitute apparatus (or main body engaged with the smoking substitute apparatus) may comprise a power source.
  • the power source may be electrically connected (or connectable) to a heater of the smoking substitute apparatus (e.g. when the smoking substitute apparatus is engaged with the main body).
  • the power source may be a battery (e.g. a rechargeable battery).
  • a connector in the form of e.g. a USB port may be provided for recharging this battery.
  • the smoking substitute apparatus When the smoking substitute apparatus is in the form of a consumable, the smoking substitute apparatus may comprise an electrical interface for interfacing with a corresponding electrical interface of the main body. One or both of the electrical interfaces may include one or more electrical contacts. Thus, when the main body is engaged with the consumable, the electrical interface of the main body may be configured to transfer electrical power from the power source to a heater of the consumable via the electrical interface of the consumable.
  • the electrical interface of the smoking substitute apparatus may also be used to identify the smoking substitute apparatus (in the form of a consumable) from a list of known types.
  • the consumable may have a certain concentration of nicotine and the electrical interface may be used to identify this.
  • the electrical interface may additionally or alternatively be used to identify when a consumable is connected to the main body.
  • the main body may comprise an identification means, which may, for example, be in the form of an RFID reader, a barcode or QR code reader.
  • This identification means may be able to identify a characteristic (e.g. a type) of a consumable engaged with the main body.
  • the consumable may include any one or more of an RFID chip, a barcode or QR code, or memory within which is an identifier and which can be interrogated via the identification means.
  • the smoking substitute apparatus or main body may comprise a controller, which may include a microprocessor. The controller may be configured to control the supply of power from the power source to the heater of the smoking substitute apparatus (e.g. via the electrical contacts).
  • a memory may be provided and may be operatively connected to the controller.
  • the memory may include non-volatile memory.
  • the memory may include instructions which, when implemented, cause the controller to perform certain tasks or steps of a method.
  • the main body or smoking substitute apparatus may comprise a wireless interface, which may be configured to communicate wirelessly with another device, for example a mobile device, e.g. via Bluetooth®.
  • the wireless interface could include a Bluetooth® antenna.
  • Other wireless communication interfaces, e.g. WiFi®, are also possible.
  • the wireless interface may also be configured to communicate wirelessly with a remote server.
  • a puff sensor may be provided that is configured to detect a puff (i.e. inhalation from a user).
  • the puff sensor may be operatively connected to the controller so as to be able to provide a signal to the controller that is indicative of a puff state (i.e. puffing or not puffing).
  • the puff sensor may, for example, be in the form of a pressure sensor or an acoustic sensor. That is, the controller may control power supply to the heater of the consumable in response to a puff detection by the sensor. The control may be in the form of activation of the heater in response to a detected puff. That is, the smoking substitute apparatus may be configured to be activated when a puff is detected by the puff sensor.
  • the puff sensor When the smoking substitute apparatus is in the form of a consumable, the puff sensor may be provided in the consumable or alternatively may be provided in the main body.
  • flavourant is used to describe a compound or combination of compounds that provide flavour and/or aroma.
  • the flavourant may be configured to interact with a sensory receptor of a user (such as an olfactory or taste receptor).
  • the flavourant may include one or more volatile substances.
  • the flavourant may be provided in solid or liquid form.
  • the flavourant may be natural or synthetic.
  • the flavourant may include menthol, liquorice, chocolate, fruit flavour (including e.g. citrus, cherry etc.), vanilla, spice (e.g. ginger, cinnamon) and tobacco flavour.
  • the flavourant may be evenly dispersed or may be provided in isolated locations and/or varying concentrations.
  • the present inventors consider that a flow rate of 1 .3 L min 1 is towards the lower end of a typical user expectation of flow rate through a conventional cigarette and therefore through a user-acceptable smoking substitute apparatus.
  • the present inventors further consider that a flow rate of 2.0 L min 1 is towards the higher end of a typical user expectation of flow rate through a conventional cigarette and therefore through a user-acceptable smoking substitute apparatus.
  • Embodiments of the present invention therefore provide an aerosol with advantageous particle size characteristics across a range of flow rates of air through the apparatus.
  • the aerosol may have a Dv50 of at least 1 .1 pm, at least 1 .2 pm, at least 1 .3 pm, at least 1 .4 pm, at least 1 .5 pm, at least 1 .6 pm, at least 1 .7 pm, at least 1 .8 pm, at least 1 .9 pm or at least 2.0 pm.
  • the aerosol may have a Dv50 of not more than 4.9 pm, not more than 4.8 pm, not more than 4.7 pm, not more than 4.6 pm, not more than 4.5 pm, not more than 4.4 pm, not more than 4.3 pm, not more than 4.2
  • a particularly preferred range for Dv50 of the aerosol is in the range 2-3 pm.
  • the air inlet, flow passage, outlet and the vaporisation chamber may be configured so that, when the air flow rate inhaled by the user through the apparatus is 1 .3 L min -1 , the average magnitude of velocity of air in the vaporisation chamber is in the range 0-1 .3 ms -1 .
  • the average magnitude velocity of air may be calculated based on knowledge of the geometry of the vaporisation chamber and the flow rate.
  • the average magnitude of velocity of air in the vaporisation chamber may be at least 0.001 ms -1 , or at least 0.005 ms -1 , or at least 0.01 ms -1 , or at least 0.05 ms -1 .
  • the average magnitude of velocity of air in the vaporisation chamber may be at most 1 .2 ms -1 , at most 1 .1 ms -1 , at most 1 .0 ms -1 , at most 0.9 ms 1 , at most 0.8 ms 1 , at most 0.7 ms 1 or at most 0.6 ms 1 .
  • the air inlet, flow passage, outlet and the vaporisation chamber may be configured so that, when the air flow rate inhaled by the user through the apparatus is 2.0 L min 1 , the average magnitude of velocity of air in the vaporisation chamber is in the range 0-1 .3 ms -1 .
  • the average magnitude velocity of air may be calculated based on knowledge of the geometry of the vaporisation chamber and the flow rate.
  • the average magnitude of velocity of air in the vaporisation chamber may be at least 0.001 ms -1 , or at least 0.005 ms -1 , or at least 0.01 ms -1 , or at least 0.05 ms -1 .
  • the average magnitude of velocity of air in the vaporisation chamber may be at most 1 .2 ms -1 , at most 1 .1 ms -1 , at most 1 .0 ms -1 , at most 0.9 ms 1 , at most 0.8 ms 1 , at most 0.7 ms 1 or at most 0.6 ms 1 .
  • the resultant aerosol particle size is advantageously controlled to be in a desirable range. It is further considered that the configuration of the apparatus can be selected so that the average magnitude of velocity of air in the vaporisation chamber can be brought within the ranges specified, at the exemplary flow rate of 1 .3 L min -1 and/or the exemplary flow rate of 2.0 L min -1 .
  • the aerosol generator may comprise a vaporiser element loaded with aerosol precursor, the vaporiser element being heatable by a heater and presenting a vaporiser element surface to air in the vaporisation chamber.
  • a vaporiser element region may be defined as a volume extending outwardly from the vaporiser element surface to a distance of 1 mm from the vaporiser element surface.
  • the air inlet, flow passage, outlet and the vaporisation chamber may be configured so that, when the air flow rate inhaled by the user through the apparatus is 1 .3 L min -1 , the average magnitude of velocity of air in the vaporiser element region is in the range 0-1 .2 ms -1 .
  • the average magnitude of velocity of air in the vaporiser element region may be calculated using computational fluid dynamics.
  • the average magnitude of velocity of air in the vaporiser element region may be at least 0.001 ms 1 , or at least 0.005 ms 1 , or at least 0.01 ms 1 , or at least 0.05 ms 1 .
  • the average magnitude of velocity of air in the vaporiser element region may be at most 1 .1 ms -1 , at most 1 .0 ms -1 , at most 0.9 ms -1 , at most 0.8 ms -1 , at most 0.7 ms -1 or at most 0.6 ms -1 .
  • the air inlet, flow passage, outlet and the vaporisation chamber may be configured so that, when the air flow rate inhaled by the user through the apparatus is 2.0 L min 1 , the average magnitude of velocity of air in the vaporiser element region is in the range 0-1 .2 ms -1 .
  • the average magnitude of velocity of air in the vaporiser element region may be calculated using computational fluid dynamics.
  • the average magnitude of velocity of air in the vaporiser element region may be at least 0.001 ms 1 , or at least 0.005 ms 1 , or at least 0.01 ms 1 , or at least 0.05 ms 1 .
  • the average magnitude of velocity of air in the vaporiser element region may be at most 1 .1 ms -1 , at most 1 .0 ms -1 , at most 0.9 ms -1 , at most 0.8 ms -1 , at most 0.7 ms -1 or at most 0.6 ms -1 .
  • the resultant aerosol particle size is advantageously controlled to be in a desirable range. It is further considered that the velocity of air in the vaporiser element region is more relevant to the resultant particle size characteristics than consideration of the velocity in the vaporisation chamber as a whole. This is in view of the significant effect of the velocity of air in the vaporiser element region on the cooling of the vapour emitted from the vaporiser element surface.
  • the air inlet, flow passage, outlet and the vaporisation chamber may be configured so that, when the air flow rate inhaled by the user through the apparatus is 1 .3 L min -1 , the maximum magnitude of velocity of air in the vaporiser element region is in the range 0-2.0 ms -1 .
  • the maximum magnitude of velocity of air in the vaporiser element region may be at least 0.001 ms -1 , or at least 0.005 ms -1 , or at least 0.01 ms -1 , or at least 0.05 ms -1 .
  • the maximum magnitude of velocity of air in the vaporiser element region may be at most 1 .9 ms -1 , at most 1 .8 ms -1 , at most 1 .7 ms -1 , at most 1 .6 ms -1 , at most 1 .5 ms -1 , at most 1 .4 ms -1 , at most 1 .3 ms -1 or at most 1 .2 ms -1 .
  • the air inlet, flow passage, outlet and the vaporisation chamber may be configured so that, when the air flow rate inhaled by the user through the apparatus is 2.0 L min- 1 , the maximum magnitude of velocity of air in the vaporiser element region is in the range 0-2.0 ms -1 .
  • the maximum magnitude of velocity of air in the vaporiser element region may be at least 0.001 ms -1 , or at least 0.005 ms -1 , or at least 0.01 ms -1 , or at least 0.05 ms -1 .
  • the maximum magnitude of velocity of air in the vaporiser element region may be at most 1 .9 ms -1 , at most 1 .8 ms -1 , at most 1 .7 ms -1 , at most 1 .6 ms -1 , at most 1 .5 ms -1 , at most 1 .4 ms -1 , at most 1 .3 ms -1 or at most 1 .2 ms -1 .
  • the air inlet, flow passage, outlet and the vaporisation chamber may be configured so that, when the air flow rate inhaled by the user through the apparatus is 1 .3 L min -1 , the turbulence intensity in the vaporiser element region is not more than 1 %.
  • the turbulence intensity in the vaporiser element region may be not more than 0.95%, not more than 0.9%, not more than 0.85%, not more than 0.8%, not more than 0.75%, not more than 0.7%, not more than 0.65% or not more than 0.6%.
  • the particle size characteristics of the generated aerosol may be determined by the cooling rate experienced by the vapour after emission from the vaporiser element (e.g. wick).
  • the vaporiser element e.g. wick
  • imposing a relatively slow cooling rate on the vapour has the effect of generating aerosols with a relatively large particle size.
  • the parameters discussed above are considered to be mechanisms for implementing a particular cooling dynamic to the vapour.
  • the air inlet, flow passage, outlet and the vaporisation chamber may be configured so that a desired cooling rate is imposed on the vapour.
  • the particular cooling rate to be used depends of course on the nature of the aerosol precursor and other conditions. However, for a particular aerosol precursor it is possible to define a set of testing conditions in order to define the cooling rate, and by extension this imposes limitations on the configuration of the apparatus to permit such cooling rates as are shown to result in advantageous aerosols.
  • the air inlet, flow passage, outlet and the vaporisation chamber may be configured so that the cooling rate of the vapour is such that the time taken to cool to 50 °C is not less than 16 ms, when tested according to the following protocol.
  • the aerosol precursor is an e-liquid consisting of 1 .6% freebase nicotine and the remainder a 65:35 propylene glycol and vegetable glycerine mixture, the e-liquid having a boiling point of 209 °C.
  • Air is drawn into the air inlet at a temperature of 25 °C.
  • the vaporiser is operated to release a vapour of total particulate mass 5 mg over a 3 second duration from the vaporiser element surface in an air flow rate between the air inlet and outlet of 1 .3 L min -1 .
  • the air inlet, flow passage, outlet and the vaporisation chamber may be configured so that the cooling rate of the vapour is such that the time taken to cool to 50 °C is not less than 16 ms, when tested according to the following protocol.
  • the aerosol precursor is an e-liquid consisting of 1 .6% freebase nicotine and the remainder a 65:35 propylene glycol and vegetable glycerine mixture, the e-liquid having a boiling point of 209 °C.
  • Air is drawn into the air inlet at a temperature of 25 °C.
  • the vaporiser is operated to release a vapour of total particulate mass 5 mg over a 3 second duration from the vaporiser element surface in an air flow rate between the air inlet and outlet of 2.0 L min -1 .
  • Cooling of the vapour such that the time taken to cool to 50 °C is not less than 16 ms corresponds to an equivalent linear cooling rate of not more than 10 °C/ms.
  • the equivalent linear cooling rate of the vapour to 50 °C may be not more than 9 °C/ms, not more than 8 °C/ms, not more than 7 °C/ms, not more than 6 °C/ms or not more than 5 °C/ms.
  • Cooling of the vapour such that the time taken to cool to 50 °C is not less than 32 ms corresponds to an equivalent linear cooling rate of not more than 5 °C/ms.
  • the testing protocol set out above considers the cooling of the vapour (and subsequent aerosol) to a temperature of 50 °C. This is a temperature which can be considered to be suitable for an aerosol to exit the apparatus for inhalation by a user without causing significant discomfort. It is also possible to consider cooling of the vapour (and subsequent aerosol) to a temperature of 75 °C. Although this temperature is possibly too high for comfortable inhalation, it is considered that the particle size characteristics of the aerosol are substantially settled by the time the aerosol cools to this temperature (and they may be settled at still higher temperature).
  • the air inlet, flow passage, outlet and the vaporisation chamber may be configured so that the cooling rate of the vapour is such that the time taken to cool to 75 °C is not less than 4.5 ms, when tested according to the following protocol.
  • the aerosol precursor is an e-liquid consisting of 1 .6% freebase nicotine and the remainder a 65:35 propylene glycol and vegetable glycerine mixture, the e- liquid having a boiling point of 209 °C.
  • Air is drawn into the air inlet at a temperature of 25 °C.
  • the vaporiser is operated to release a vapour of total particulate mass 5 mg over a 3 second duration from the vaporiser element surface in an air flow rate between the air inlet and outlet of 1 .3 L min -1 .
  • the air inlet, flow passage, outlet and the vaporisation chamber may be configured so that the cooling rate of the vapour is such that the time taken to cool to 75 °C is not less than 4.5 ms, when tested according to the following protocol.
  • the aerosol precursor is an e-liquid consisting of 1 .6% freebase nicotine and the remainder a 65:35 propylene glycol and vegetable glycerine mixture, the e-liquid having a boiling point of 209 °C.
  • Air is drawn into the air inlet at a temperature of 25 °C.
  • the vaporiser is operated to release a vapour of total particulate mass 5 mg over a 3 second duration from the vaporiser element surface in an air flow rate between the air inlet and outlet of 2.0 L min -1 .
  • the equivalent linear cooling rate of the vapour to 75 °C may be not more than 29 °C/ms, not more than 28 °C/ms, not more than 27 °C/ms, not more than 26 °C/ms, not more than 25 °C/ms, not more than 24
  • Cooling of the vapour such that the time taken to cool to 75 °C is not less than 13 ms corresponds to an equivalent linear cooling rate of not more than 10 °C/ms.
  • the air flow disruptor is disposed in the air flow path at or downstream of the first position, defined in terms of a location in the air flow at which the particle size characteristics of the aerosol are substantially fixed because the aerosol has fully developed.
  • the average temperature of the aerosol droplets at the first position may be at least 75°C. More preferably, in view of the effect of a high temperature on the development of advantageous aerosols, this average temperature may be at least 76°C, at least 77°C, at least 78°C, at least 79°C, or at least 80°C.
  • the temperature of the aerosol droplets is assessed by measuring the temperature of the aerosol and the associated carrier gas flow (i.e. associated air flow). This is reasonable because the temperature of the aerosol droplets themselves and the carrier gas is substantially the same once the particle size characteristics of the aerosol have settled.
  • the measurement of the temperature of the aerosol droplets is carried out in a similar way at the first position as at the second position.
  • the average temperature of the aerosol droplets at the second position may be not more than 55°C. More preferably, in view of the comfort of the user, this average temperature may be not more than 54°C, not more than 53°C, not more than 52°C, not more than 51 °C, or not more than 50°C.
  • the predetermined particle size characteristics of the aerosol at the first position and the second position may include the characteristic that the Dv50 particle size of the aerosol is in the range 2-5 pm.
  • Preferred ranges for the particle size characteristics of the aerosol delivered to the user may be as set out above.
  • each inhale may be of at least one second duration (and typically not more than three second duration).
  • a first inhale of said series takes place without a preceding inhale, or with a time delay of at least one minute from a preceding inhale. In this state, the apparatus will be considered to be “cold”.
  • a second inhale takes place after the first inhale and with a time delay after the end of the first inhale of not less than 10 seconds and not more than 30 seconds.
  • the apparatus will be considered to be “warm”.
  • the effect of this is that the aerosol droplets received by the user during the second (and/or subsequent) inhale would be warmer that during the first inhale. This can have a significant effect on the user.
  • the average temperature of the aerosol droplets during the first inhale may be acceptable but the average temperature of the aerosol droplets during the second (and/or subsequent) inhale may be unacceptably warm.
  • the average temperature of the aerosol droplets at the second position for the second inhale is within 10°C of the average temperature of the aerosol droplets at the second position for the first inhale. More preferably, this temperature difference is not more than 9°C, not more than 8°C, not more than 7°C, not more than 6°C, not more than 5°C, not more than 4°C, not more than 3°C, not more than 2°C, or not more than 1 °C.
  • the configuration of the smoking substitute apparatus may be such that all of the air flow at the outlet passes through the vaporisation chamber, or that some of the air flow at the outlet derives from an auxiliary air inlet, or that the vaporisation chamber is substantially stagnant.
  • the air flow path between the air inlet and the outlet may pass through the vaporisation chamber.
  • all of the air flow at the outlet passes through the vaporisation chamber.
  • vaporisation chamber can be considered as having a vaporisation chamber outlet.
  • the air flow path between the air inlet and the outlet may bypass the vaporisation chamber and entrain aerosol particles from the vaporisation chamber outlet.
  • the vaporisation chamber may be substantially stagnant, configured to deliver vapour and/or aerosol to the air flow via the vaporisation chamber outlet.
  • An air flow path between the air inlet and the outlet may pass through the vaporisation chamber.
  • the air flow disruptor may comprise a protrusion extending into the air flow path laterally from a side wall of the aerosol delivery conduit.
  • the aerosol delivery conduit may have a tapered portion whose cross sectional area, when viewed in a plane perpendicular to a principal axis of the aerosol delivery conduit, reduces with progression along the principal axis in the upstream to downstream direction of the aerosol delivery conduit. With this configuration, the velocity of the air flow increases along the tapered portion.
  • the tapered portion of the aerosol delivery conduit may extend for at least one quarter of the axial length of the aerosol delivery conduit.
  • the protrusion of the flow disruptor may extend from the side wall of the aerosol delivery conduit at the tapered portion of the aerosol delivery conduit.
  • the protrusion of the flow disruptor When the protrusion of the flow disruptor extends from the side wall of the aerosol delivery conduit, the protrusion may be considered to extend in a direction substantially perpendicular to the principal axis of the aerosol delivery conduit towards the principal axis of the aerosol delivery conduit for a radial protrusion distance of less than half of the diameter of the aerosol delivery conduit at the position of the protrusion. When viewed along the principal axis of the aerosol delivery conduit, the protrusion may therefore extend less than half way across the aerosol delivery conduit.
  • the protrusion may include an air flow facing surface.
  • the air flow facing surface may be disposed obliquely to the principal axis of the aerosol delivery conduit.
  • the air flow facing surface may be positioned to be impacted by air flowing in the aerosol delivery conduit from the upstream to downstream direction.
  • the air flow facing surface of the protrusion may be substantially planar.
  • the axial length of the protrusion, projected along the axial direction of the aerosol delivery conduit, may be between 0.5 and 2 times the radial protrusion distance.
  • the circumferential length of the protrusion, projected along a direction around the circumference of the aerosol delivery conduit, may be between 0.5 and 2 times the radial protrusion distance.
  • the protrusion may have the form of a blade or a tab.
  • the shape of the protrusion is preferably selected in order to partially divide the air flow in the aerosol delivery conduit.
  • the invention includes the combination of the aspects and optional features described except where such a combination is clearly impermissible or expressly avoided.
  • Figure 1 illustrates a set of rectangular tubes for use in experiments to assess the effect of flow and cooling conditions at the wick on aerosol properties.
  • Each tube has the same depth and length but different width.
  • Figure 2 shows a schematic perspective longitudinal cross sectional view of an example rectangular tube with a wick and heater coil installed.
  • Figure 3 shows a schematic transverse cross sectional view an example rectangular tube with a wick and heater coil installed.
  • the internal width of the tube is 12 mm.
  • Figures 4A-4D show air flow streamlines in the four devices used in a turbulence study.
  • Figure 5 shows the experimental set up to investigate the influence of inflow air temperature on aerosol particle size, in order to investigate the effect of vapour cooling rate on aerosol generation.
  • Figure 6 shows a schematic longitudinal cross sectional view of a first smoking substitute apparatus (pod 1 ) used to assess influence of inflow air temperature on aerosol particle size.
  • Figure 7 shows a schematic longitudinal cross sectional view of a second smoking substitute apparatus (pod 2) used to assess influence of inflow air temperature on aerosol particle size.
  • Figure 8A shows a schematic longitudinal cross sectional view of a third smoking substitute apparatus (pod 3) used to assess influence of inflow air temperature on aerosol particle size.
  • Figure 8B shows a schematic longitudinal cross sectional view of the same third smoking substitute apparatus (pod 3) in a direction orthogonal to the view taken in Figure 8A.
  • Figure 9 shows a plot of aerosol particle size (Dv50) experimental results against calculated air velocity.
  • Figure 10 shows a plot of aerosol particle size (Dv50) experimental results against the flow rate through the apparatus for a calculated air velocity of 1 m/s.
  • Figure 11 shows a plot of aerosol particle size (Dv50) experimental results against the average magnitude of the velocity in the vaporiser surface region, as obtained from CFD modelling.
  • Figure 12 shows a plot of aerosol particle size (Dv50) experimental results against the maximum magnitude of the velocity in the vaporiser surface region, as obtained from CFD modelling.
  • Figure 13 shows a plot of aerosol particle size (Dv50) experimental results against the turbulence intensity.
  • Figure 14 shows a plot of aerosol particle size (Dv50) experimental results dependent on the temperature of the air and the heating state of the apparatus.
  • Figure 15 shows a plot of aerosol particle size (Dv50) experimental results against vapour cooling rate to 50°C.
  • Figure 16 shows a plot of aerosol particle size (Dv50) experimental results against vapour cooling rate to 75°C.
  • Figure 17 is a schematic front view of a smoking substitute system, according to a first reference arrangement, in an engaged position
  • Figure 18 is a schematic front view of the smoking substitute system of the first reference arrangement in a disengaged position
  • Figure 19 is a schematic longitudinal cross sectional view of a smoking substitute apparatus of a second reference arrangement
  • Figure 20 is an enlarged schematic cross sectional view of part of the air passage and vaporisation chamber of the second reference arrangement
  • Figure 21 shows a schematic cross sectional view of a smoking substitute apparatus of a third reference arrangement
  • Figure 22 shows a schematic cross sectional view of a smoking substitute apparatus of a fourth reference arrangement
  • Figure 23 shows a schematic axial view of part of a smoking substitute apparatus according to an embodiment of the invention.
  • Figure 24 shows a schematic perspective sectional view of part of the smoking substitute apparatus of Figure 23;
  • Figure 25 shows a graph of the vapour (aerosol) temperature experienced by a user according to an embodiment of the invention and according to a comparative example.
  • FIGS 17 and 18 illustrate a smoking substitute system in the form of an e-cigarette system 110.
  • the system 110 comprises a main body 120 of the system 110, and a smoking substitute apparatus in the form of an e-cigarette consumable (or “pod”) 150.
  • the consumable 150 (sometimes referred to herein as a smoking substitute apparatus) is removable from the main body 120, so as to be a replaceable component of the system 110.
  • the e-cigarette system 110 is a closed system in the sense that it is not intended that the consumable should be refillable with e-liquid by a user.
  • the consumable 150 is configured to engage the main body 120.
  • Figure 17 shows the main body 120 and the consumable 150 in an engaged state
  • Figure 18 shows the main body 120 and the consumable 150 in a disengaged state.
  • a portion of the consumable 150 is received in a cavity of corresponding shape in the main body 120 and is retained in the engaged position by way of a snap-engagement mechanism.
  • the main body 120 and consumable 150 may be engaged by screwing one into (or onto) the other, or through a bayonet fitting, or by way of an interference fit.
  • the system 110 is configured to vaporise an aerosol precursor, which in the illustrated reference arrangement is in the form of a nicotine-based e-liquid 160.
  • the e-liquid 160 comprises nicotine and a base liquid including propylene glycol and/or vegetable glycerine.
  • the e-liquid 160 is flavoured by a flavourant.
  • the e-liquid 160 may be flavourless and thus may not include any added flavourant.
  • FIG 19 shows a schematic longitudinal cross sectional view of a reference arrangement of the smoking substitute apparatus forming part of the smoking substitute system shown in Figures 17 and 18.
  • the e-liquid 160 is stored within a reservoir in the form of a tank 152 that forms part of the consumable 150.
  • the consumable 150 is a “single-use” consumable 150. That is, upon exhausting the e-liquid 160 in the tank 152, the intention is that the user disposes of the entire consumable 150.
  • the term “single-use” does not necessarily mean the consumable is designed to be disposed of after a single smoking session. Rather, it defines that the consumable 150 is not arranged to be refilled after the e-liquid contained in the tank 152 is depleted.
  • the tank may include a vent (not shown) to allow ingress of air to replace e-liquid that has been used from the tank.
  • the consumable 150 preferably includes a window 158 (see Figures 17 and 18), so that the amount of e-liquid in the tank 152 can be visually assessed.
  • the main body 120 includes a slot 157 so that the window 158 of the consumable 150 can be seen whilst the rest of the tank 152 is obscured from view when the consumable 150 is received in the cavity of the main body 120.
  • the consumable 150 may be referred to as a “clearomizer” when it includes a window 158, or a “cartomizer” when it does not.
  • the e-liquid i.e. aerosol precursor
  • the tank may be refillable with e-liquid or the e-liquid may be stored in a nonconsumable component of the system.
  • the e-liquid may be stored in a tank located in the main body or stored in another component that is itself not single-use (e.g. a refillable cartomizer).
  • the external wall of tank 152 is provided by a casing of the consumable 150.
  • the tank 152 annularly surrounds, and thus defines a portion of, a passage 170 that extends between a vaporiser inlet 172 and an outlet 174 at opposing ends of the consumable 150.
  • the passage 170 comprises an upstream end at the end of the consumable 150 that engages with the main body 120, and a downstream end at an opposing end of the consumable 150 that comprises a mouthpiece 154 of the system 1 10.
  • a plurality of device air inlets 176 are formed at the boundary between the casing of the consumable and the casing of the main body.
  • the device air inlets 176 are in fluid communication with the vaporiser inlet 172 through an inlet flow channel 178 formed in the cavity of the main body which is of corresponding shape to receive a part of the consumable 150. Air from outside of the system 1 10 can therefore be drawn into the passage 170 through the device air inlets 176 and the inlet flow channels 178.
  • the passage 170 may be partially defined by a tube (e.g. a metal tube) extending through the consumable 150.
  • the passage 170 is shown with a substantially circular cross-sectional profile with a constant diameter along its length.
  • the passage may have other cross-sectional profiles, such as oval shaped or polygonal shaped profiles.
  • the cross sectional profile and the diameter (or hydraulic diameter) of the passage may vary along its longitudinal axis.
  • the smoking substitute system 1 10 is configured to vaporise the e-liquid 160 for inhalation by a user.
  • the consumable 150 comprises a heater having a porous wick 162 and a resistive heating element in the form of a heating filament 164 that is helically wound (in the form of a coil) around a portion of the porous wick 162.
  • the porous wick 162 extends across the passage 170 (i.e. transverse to a longitudinal axis of the passage 170 and thus also transverse to the air flow along the passage 170 during use) and opposing ends of the wick 162 extend into the tank 152 (so as to be immersed in the e-liquid 160).
  • e-liquid 160 contained in the tank 152 is conveyed from the opposing ends of the porous wick 162 to a central portion of the porous wick 162 so as to be exposed to the airflow in the passage 170.
  • the helical filament 164 is wound about the exposed central portion of the porous wick 162 and is electrically connected to an electrical interface in the form of electrical contacts 156 mounted at the end of the consumable that is proximate the main body 120 (when the consumable and the main body are engaged). When the consumable 150 is engaged with the main body 120, electrical contacts 156 make contact with corresponding electrical contacts (not shown) of the main body 120.
  • the main body electrical contacts are electrically connectable to a power source (not shown) of the main body 120, such that (in the engaged position) the filament 164 is electrically connectable to the power source.
  • a power source not shown
  • the filament 164 is electrically connectable to the power source.
  • power can be supplied by the main body 120 to the filament 164 in order to heat the filament 164.
  • This heats the porous wick 162 which causes e-liquid 160 conveyed by the porous wick 162 to vaporise and thus to be released from the porous wick 162.
  • the vaporised e-liquid becomes entrained in the airflow and, as it cools in the airflow (between the heated wick and the outlet 174 of the passage 170), condenses to form an aerosol.
  • This aerosol is then inhaled, via the mouthpiece 154, by a user of the system 110.
  • e-liquid is lost from the heated portion of the wick, further e-liquid is drawn along the wick from the tank to replace the e-liquid lost from the heated portion of the wick.
  • the filament 164 and the exposed central portion of the porous wick 162 are positioned across the passage 170. More specifically, the part of passage that contains the filament 164 and the exposed portion of the porous wick 162 forms a vaporisation chamber.
  • the vaporisation chamber has the same cross-sectional diameter as the passage 170. However, in some embodiments the vaporisation chamber may have a different cross sectional profile compared with the passage 170. For example, the vaporisation chamber may have a larger cross sectional diameter than at least some of the downstream part of the passage 170 so as to enable a longer residence time for the air inside the vaporisation chamber.
  • FIG 20 illustrates in more detail the vaporisation chamber and therefore the region of the consumable 150 around the wick 162 and filament 164.
  • the helical filament 164 is wound around a central portion of the porous wick 162.
  • the porous wick extends across passage 170.
  • E-liquid 160 contained within the tank 152 is conveyed as illustrated schematically by arrows 401 , i.e. from the tank and towards the central portion of the porous wick 162.
  • porous wick 162 When the user inhales, air is drawn from through the inlets 176 shown in Figure 19, along inlet flow channel 178 to vaporisation chamber inlet 172 and into the vaporisation chamber containing porous wick 162.
  • the porous wick 162 extends substantially transverse to the airflow direction.
  • the airflow passes around the porous wick, at least a portion of the airflow substantially following the surface of the porous wick 162.
  • the airflow may follow a curved path around an outer periphery of the porous wick 162.
  • the power source of the main body 120 may be in the form of a battery (e.g. a rechargeable battery such as a lithium ion battery).
  • the main body 120 may comprise a connector in the form of e.g. a USB port for recharging this battery.
  • the main body 120 may also comprise a controller that controls the supply of power from the power source to the main body electrical contacts (and thus to the filament 164). That is, the controller may be configured to control a voltage applied across the main body electrical contacts, and thus the voltage applied across the filament 164. In this way, the filament 164 may only be heated under certain conditions (e.g. during a puff and/or only when the system is in an active state).
  • the main body 120 may include a puff sensor (not shown) that is configured to detect a puff (i.e. inhalation).
  • the puff sensor may be operatively connected to the controller so as to be able to provide a signal, to the controller, which is indicative of a puff state (i.e. puffing or not puffing).
  • the puff sensor may, for example, be in the form of a pressure sensor or an acoustic sensor.
  • the main body 120 and consumable 150 may comprise a further interface which may, for example, be in the form of an RFID reader, a barcode or QR code reader.
  • This interface may be able to identify a characteristic (e.g. a type) of a consumable 150 engaged with the main body 120.
  • the consumable 150 may include any one or more of an RFID chip, a barcode or QR code, or memory within which is an identifier and which can be interrogated via the interface.
  • An apparatus may be configured such that in use, at least part of the air flow drawn by a user through the apparatus from the air inlet to the outlet bypasses the vaporisation chamber defined by the enclosure.
  • a second reference arrangement of an apparatus shown in Figure 21 , provides an example of how such a bypassing air flow may be created. Accordingly, some embodiments of the invention may include one or a combination of the features of the second reference arrangement (and variations thereof) where such features are combinable with the present invention. This second reference arrangement is described below.
  • Figure 21 illustrates a schematic longitudinal cross sectional view of a third reference arrangement of the smoking substitute apparatus forming part of the smoking substitute system shown in Figures 17 and 18.
  • the arrangement illustrated in Figure 21 differs from the reference arrangement illustrated in Figure 19 in that the substitute smoking apparatus includes two bypass passages 180 in addition to the vaporiser passage 170.
  • the bypass air passages extend between the plurality of device air inlets 176 and two outlets 184.
  • the number of bypass passages 180 and corresponding outlets 184 may be greater or smaller than in the illustrated example.
  • the bypass passage 180 is shown with a substantially circular cross-sectional profile with a constant diameter along its length.
  • the bypass passage 180 may have other cross-sectional profiles, such as oval shaped or polygonal shaped profiles.
  • the cross sectional profile and the diameter (or hydraulic diameter) of the bypass passage 180 may vary along its longitudinal axis.
  • the smoking substitute apparatus 150a of the third reference arrangement can deliver a more consistent aerosol to a user.
  • the smoking substitute apparatus 150a of the third reference arrangement is capable of producing an increased particle droplet size, dso, based on typical inhalation rates undertaken by a user, compared to the reference arrangement of Figure 19.
  • Such larger droplet sizes may be beneficial for the delivery of vapour to a user’s lungs.
  • the preferred ratio between the dimensions of the bypass passage 180 and the dimensions of the vaporiser passage 170, and hence flow rate in the respective passages may be determined from representative user inhalation rates and from the required air flow rate through the vaporisation chamber to deliver a desired droplet size.
  • an average total flow rate of 1 .3 litres per minute may be split such that 0.8 litres per minute passes through the bypass air channel 180, and 0.5 litres per minute passes through the vaporiser channel 170, a bypass:vaporiser flow rate ratio of 1 .6:1 .
  • Such a flow rate may provide an average droplet size, dso, of 1 -3 pm (more preferably 2-3 pm) with a span of not more than 20 (preferably not more than 10).
  • Alternative flow rate ratios may be provided based on calculations and measurements of user flow rate, vaporiser flow rate, and average droplet size dso.
  • a bypass vaporiser flow rate ratio of between 0.5:1 and 20:1 typically at an average total flow rate of 1 .3 litres per minute may be advantageous depending on the configuration of the smoking substitute apparatus.
  • the bypass passage and vaporiser passage extend from a common device inlet 176. This has the benefit of ensuring more consistent airflow through the bypass passage 180 and vaporiser passage 170 across the lifetime of the smoking substitute apparatus 150a, since any obstruction that impinges on an air inlet 176 will affect the airflow through both passages equally. The impact of inlet manufacturing variations can also be reduced for the same reason. This can therefore improve the user experience for the smoking substitute apparatus 150a. Furthermore, the provision of a common device inlet 176 simplifies the construction and external appearance of the device.
  • bypass passage 180 and vaporiser passage 170 separate upstream of the vaporisation chamber. Therefore, no vapour is drawn through the bypass passage 180. Furthermore, because the bypass passage leads to outlet 184 that is separate from outlet 174 of the vaporiser passage, substantially no mixing of the bypass air and vaporiser air occurs within the smoking substitute apparatus 150a. Such mixing could otherwise lead to excessive cooling of the vapour and hence a build-up of condensation within the smoking substitute apparatus 150a. Such condensation could have adverse implications for delivering vapour to the user, for example by causing the user to draw liquid droplets rather than vapour when “puffing” on the mouthpiece 154.
  • a further example of a bypass air flow is presented by a fourth reference arrangement. Accordingly, in some embodiments, the apparatus may include one or a combination of features of a fourth reference arrangement (and variations thereof), shown schematically in Figure 22, where such features are combinable with the present invention. This fourth reference arrangement is described below.
  • Figure 22 illustrates a longitudinal cross sectional view of a consumable 250 according to a fourth reference arrangement.
  • the consumable 250 is shown attached, at a first end of the consumable 250, to the main body 120 of Figure 17 and Figure 18. More specifically, the consumable 250 is configured to engage and disengage with the main body 120 and is interchangeable with the reference arrangement 150 as shown in Figures 19 and 20. Furthermore, the consumable 250 is configured to interact with the main body 120 in the same manner as the reference arrangement 150 and the user may operate the consumable 250 in the same manner as the reference arrangement 150.
  • the consumable 250 comprises a housing.
  • the consumable 250 comprises an aerosol generation chamber 280 in the housing.
  • the aerosol generation chamber 280 takes the form of an open ended container, or a cup, with a single chamber outlet 282 opened towards the outlet 274 of the consumable 250.
  • the housing has a plurality of air inlets 272 defined or opened at the sidewall of the housing.
  • An outlet 274 is defined or opened at a second end of the consumable 250 that comprises a mouthpiece 254.
  • a pair of passages 270 each extend between the respective air inlets 272 and the outlet 274 to provide flow passage for an air flow 412 as a user puffs on the mouthpiece 254.
  • the chamber outlet 282 is configured to be in fluid communication with the passages 270.
  • the passages 270 extend from the air inlets 272 towards the first end of the consumable 250 before routing back to towards the outlet 274 at the second end of the consumable 250. That is, a portion of each of the passages 270 axially extends alongside the aerosol generation chamber 280.
  • the passages 270 may extend from the air inlet 272 directly to the outlet 274 without routing towards the first end of consumable 250, e.g. the passages 270 may not axially extend alongside the aerosol generation chamber 280.
  • the housing may not be provided with any air inlet for an air flow to enter the housing.
  • the chamber outlet may be directly connected to the outlet of the housing by an aerosol passage and therefore said aerosol passage may only convey aerosol as generated in the aerosol generation chamber.
  • the discharge of aerosol may be driven at least in part by the pressure increase during vaporisation of aerosol form.
  • the chamber outlet 282 is positioned downstream from the heater in the direction of the vapour and/or aerosol flow 414 and serves as the only gas flow passage to the internal volume of the aerosol generation chamber 280.
  • the aerosol generation chamber 280 is sealed against air flow except for having the chamber outlet 282 in communication with the passages 270, the chamber outlet 282 permitting, in use, aerosol generated by the heater to be entrained into an air flow along the passage 270.
  • the sealed aerosol generation chamber 280 may comprise a plurality of chamber outlets 282 each arranged in fluid commutation with the passages 270.
  • the aerosol generation chamber 280 does not comprise any aperture upstream of the heater that may serve as an air flow inlet (although in some arrangements a vent may be provided).
  • the passages 270 of the consumable 250 allow the air flow, e.g. an entire amount of air flow, entering the housing to bypass the aerosol generation chamber 280.
  • the aerosol generation chamber may be considered to be a “stagnant” chamber.
  • the volumetric flowrate of vapour and/or aerosol in the aerosol generation chamber is configured to be less than 0.1 litre per minute.
  • the vaporised aerosol precursor may cool and therefore condense to form an aerosol in the aerosol generation chamber 280, which is subsequently expulsed into or entrained with the air flow in passages 270.
  • a portion of the vaporised aerosol precursor may remain as a vapour before leaving the aerosol generation chamber 280, and subsequently forms an aerosol as it is cooled by the air flow in the passages 270.
  • the flow path of the vapour and/or aerosol 414 is illustrated in Figure 22.
  • the chamber outlet 282 is configured to be in fluid communication with a junction 290 at each of the passages 270 through a respective vapour channel 292.
  • the junctions 290 merge the vapour channels 292 with their respective passages 270 such that vapour and/or aerosol formed in the aerosol generation chamber 280 may expand or entrain into the passages 270 through junction inlets of said junctions 290.
  • the vapour channels form a buffering volume to minimise the amount of air flow that may back flow into the aerosol generation chamber 280.
  • the chamber outlet 282 may directly open towards the junction 290 at the passage, and therefore in such variations the vapour channel 292 may be omitted.
  • the chamber outlet may be closed by a one way valve.
  • Said one way valve may be configured to allow a one way flow passage for the vapour and/or aerosol to be discharged from the aerosol generation chamber, and to reduce or prevent the air flow in the passages from entering the aerosol generation chamber.
  • the aerosol generation chamber 280 is configured to have a length of 20mm and a volume of 680mm 3 .
  • the aerosol generation chamber is configured to allow vapour to be expulsed through the chamber outlet at a rate greater than 0.1 mg/second.
  • the aerosol generation chamber may be configured to have an internal volume ranging between 68mm 3 to 680mm 3 , wherein the length of the aerosol generation chamber may range between 2mm to 20mm.
  • each of the passages 270 axially extends alongside the aerosol generation chamber 280.
  • the passages 270 are formed between the aerosol generation chamber 280 and the housing. Such an arrangement reduces heat transfer from the aerosol generation chamber 280 to the external surfaces of the housing.
  • the aerosol generation chamber 280 comprises a heater extending across its width.
  • the heater comprises a porous wick 262 and a heating filament 264 helically wound around a portion of the porous wick 162.
  • a tank 252 is provided in the space between the aerosol generation chamber 280 and the outlet 274, the tank being for storing a reservoir of aerosol precursor. Therefore in contrast with the reference arrangement as shown in Figures 19 and 20, the tank 252 in the fourth reference arrangement does not substantially surround the aerosol generation chamber nor the passage 270. Instead, as shown in Figure 22, the tank is substantially positioned above the aerosol generation chamber 280 and the porous wick 262 when the consumable 250 is placed in an upright orientation during use.
  • the end portions of the porous wick 262 each extend through the sidewalls of the aerosol generation chamber 280 and into a respective liquid conduit 266 which is in fluid communication with the tank 252.
  • the wick 262, saturated with aerosol precursor, may prevent gas flow passage into the liquid conduits 266 and the tank 252.
  • Such an arrangement may allow the aerosol precursor stored in the tank 252 to convey towards the porous wick 262 through the liquid conduits 266 by gravity.
  • the liquid conduits 266 are configured to have a hydraulic diameter that allow a controlled amount of aerosol precursor to flow from the tank 252 towards the porous wick 262. More specifically, the size of liquid conduits 266 are selected based on the rate of aerosol precursor consumption during vaporisation.
  • the liquid conduits 266 are sized to allow a sufficient amount of aerosol precursor to flow towards and replenish the wick, yet not so large as to cause excessive aerosol precursor to leak into the aerosol generation chamber.
  • the liquid conduits 266 are configured to have a hydraulic diameter ranging from 0.01 mm to 10mm or 0.01 mm to 5mm.
  • the liquid conduits 266 are configured to have a hydraulic diameter in the range of 0.1 mm to 1 mm.
  • the heating filament is electrically connected to electrical contacts 256 at the base of the aerosol generation chamber 280, sealed to prevent air ingress or fluid leakage. As shown in Figure 22, when the first end of the consumable 250 is received into the main body 120, the electrical contacts 256 establish electrical communication with corresponding electrical contacts of the main body 120, and thereby allow the heater to be energised.
  • the vaporised aerosol precursor, or aerosol in the condensed form may discharge from the aerosol generation chamber 280 based on pressure difference between the aerosol generation chamber 280 and the passages 270.
  • pressure difference may arise form i) an increased pressure in the aerosol generation chamber 280 during vaporisation of aerosol form, and/or ii) a reduced pressure in the passage during a puff.
  • the heater when the heater is energised and forms a vapour, it expands in to the stagnant cavity of the aerosol generation chamber 280 and thereby causes an increase in internal pressure therein.
  • the vaporised aerosol precursor may immediately begin to cool and may form aerosol droplets.
  • Such increase in internal pressure causes convection inside the aerosol generation chamber which aids expulsing aerosol through the chamber outlet 282 and into the passages 270.
  • the heater is positioned within the stagnant cavity of the aerosol generation chamber 280, e.g. the heater is spaced from the chamber outlet 282. Such arrangement may reduce or prevent the amount of air flow entering the aerosol generation chamber, and therefore it may minimise the amount of turbulence in the vicinity of the heater.
  • the heater may be positioned adjacent to the chamber outlet and therefore that the path of vapour 414 from the heater to the chamber outlet 282 is shortened. This may allow vapour to be drawn into or entrained with the air flow in a more efficient manner.
  • junction inlet at each of the junctions 290 opens in a direction orthogonal or non-parallel to the air flow. That is, the junction inlet each opens at a sidewall of the respective passages 270. This allows the vapour and/or aerosol from the aerosol generation chamber 280 to entrain into the air flow at an angle, and thus improving localised mixing of the different streams, as well as encouraging aerosol formation.
  • the aerosol may be fully formed in the air flow and be drawn out through the outlet at the mouthpiece.
  • the aerosol as generated by the illustrated fourth reference arrangement has a median droplet size dso of at least 1 pm. More preferably, the aerosol as generated by the illustrated fourth reference arrangement has a median droplet size dso of ranged between 2pm to 3pm.
  • Figure 23 shows a schematic axial view of part of a smoking substitute apparatus according to an embodiment of the invention
  • Figure 24 shows a schematic perspective sectional view of part of the smoking substitute apparatus of Figure 23.
  • the intention is that the smoking substitute apparatus of any of the reference arrangements can be adapted using the features described with respect to Figures 23 and 24 in order to arrive at an embodiment of the invention.
  • Such an embodiment therefore comprises an air inlet, an aerosol generator for generating an aerosol from an aerosol precursor for inhalation by a user, an outlet formed at a mouthpiece, and an aerosol delivery conduit extending downstream from the aerosol generator to the outlet.
  • Figures 23 and 24 show the aerosol delivery conduit 602 formed as part of a moulded body 600 which also includes an outer housing 604 which serves as an outer wall of the tank 606 of the apparatus.
  • the apparatus includes an air flow path 608 between the air inlet and the outlet and along the aerosol delivery conduit 602 for conveying the aerosol to the user.
  • the aerosol generator heats the aerosol precursor to form vaporised aerosol precursor, the vaporised aerosol precursor being transported in the air flow and condensing to form aerosol droplets.
  • the air flow path and the aerosol generator are configured to control the air flow characteristics at the aerosol generator to provide an aerosol with predetermined particle size characteristics at a first position along the air flow path in the aerosol delivery conduit 602.
  • the first position of the aerosol delivery conduit can be taken to be the upstream extremity of thee aerosol delivery conduit.
  • An air flow disruptor 610 is disposed in the aerosol delivery conduit 602 at or downstream of the first position. The purpose of the air flow disruptor is to cause disruption of the air flow downstream of the air flow disruptor and consequently cooling of the aerosol droplets.
  • the air flow disruptor 610 comprises a protrusion extending into the air flow path laterally from a side wall 612 of the aerosol delivery conduit 602.
  • the air flow disruptor 610 is disposed in the air flow path downstream of the first position, which is a position in the air flow path at which the particle size characteristics of the aerosol are substantially fixed because the aerosol has fully developed.
  • the aerosol delivery conduit 602 has a tapered portion 614 whose cross sectional area, when viewed in a plane perpendicular to a principal axis 616 of the aerosol delivery conduit 602, reduces with progression along the principal axis in the upstream to downstream direction of the aerosol delivery conduit. With this configuration, the velocity of the air flow increases along the tapered portion.
  • the tapered portion of the aerosol delivery conduit may extend for at least one quarter of the axial length of the aerosol delivery conduit.
  • the ratio of the cross sectional area of the aerosol delivery conduit at the first position to the cross sectional area of the aerosol delivery conduit at the outlet may be at least 2.
  • the protrusion of the flow disruptor 610 extends from the side wall 612 of the aerosol delivery conduit at the tapered portion 614 of the aerosol delivery conduit. As shown in the drawings, the protrusion is positioned obliquely with respect to the air flow direction. However, when considered in the projection shown in Figure 23, the protrusion may be considered to extend in a direction substantially perpendicular to the principal axis of the aerosol delivery conduit towards the principal axis of the aerosol delivery conduit for a radial protrusion distance dr of less than half of the diameter D of the aerosol delivery conduit at the position of the protrusion. Accordingly, when viewed along the principal axis of the aerosol delivery conduit, the protrusion may therefore extend less than half way across the aerosol delivery conduit.
  • the protrusion includes an air flow facing surface 618.
  • the air flow facing surface 618 may be disposed obliquely to the principal axis 616 of the aerosol delivery conduit 602.
  • the air flow facing surface 618 may be positioned to be impacted by air flowing in the aerosol delivery conduit from the upstream to downstream direction.
  • the air flow facing surface 618 of the protrusion is substantially planar in this embodiment.
  • the axial length L a of the protrusion, projected along the axial direction of the aerosol delivery conduit, may be between 0.5 and 2 times the radial protrusion distance dr.
  • the circumferential length L c of the protrusion, projected along a direction around the circumference of the aerosol delivery conduit, may be between 0.5 and 2 times the radial protrusion distance dr.
  • the protrusion may have the form of a blade or a tab, as shown in the drawings.
  • the shape of the protrusion is preferably selected in order to partially divide the air flow in the aerosol delivery conduit. It is found that the provision of the air flow disruptor provides particularly beneficial cooling to the aerosol.
  • the air flow disruptor causing suitable disruption of the air flow downstream of the air flow disruptor with the consequential effect of cooling of the aerosol droplets so that the average temperature of the aerosol droplets at a second position in the air flow path, corresponding to the outlet formed at the mouthpiece, is not more than 60°C.
  • the aerosol particle size characteristics are substantially the same at the first position as at the second position.
  • Figure 25 shows a graph of the vapour (aerosol) temperature experienced by a user according to an embodiment of the invention and according to a comparative example.
  • the lower bar represents the vapour temperature for the first inhale in a series of inhales, at the beginning of which the apparatus is in its “cold” state, in which no preceding inhale took place within the preceding 1 minute.
  • the average vapour temperature at the mouthpiece is about 75°C.
  • the upper bar represents the vapour temperature for the second inhale in a series of inhales, taking place 20 seconds after the first inhale. The duration of each inhale was two seconds.
  • the average vapour temperature at the mouthpiece is about 90°C for the second inhale.
  • the lower bar represents the vapour temperature for the first inhale in a series of inhales, at the beginning of which the apparatus is in its “cold” state, in which no preceding inhale took place within the preceding 1 minute.
  • the average vapour temperature at the mouthpiece is about 51 °C.
  • the upper bar represents the vapour temperature for the second inhale in a series of inhales, taking place 20 seconds after the first inhale. The duration of each inhale was two seconds.
  • the average vapour temperature at the mouthpiece is about 52°C for the second inhale.
  • Aerosol droplet size is a considered to be an important characteristic for smoking substitution devices. Droplets in the range of 2-5 pm are preferred in order to achieve improved nicotine delivery efficiency and to minimise the hazard of second-hand smoking. However, at the time of writing (September 2019), commercial EVP devices typically deliver aerosols with droplet size averaged around 0.5 pm, and to the knowledge of the inventors not a single commercially available device can deliver an aerosol with an average particle size exceeding 1 pm.
  • the present inventors speculate, without themselves wishing to be bound by theory, that there has to date been a lack of understanding in the mechanisms of e-liquid evaporation, nucleation and droplet growth in the context of aerosol generation in smoking substitute devices. The present inventors have therefore studied these issues in order to provide insight into mechanisms for the generation of aerosols with larger particles. The present inventors have carried out experimental and modelling work alongside theoretical investigations, leading to significant achievements as now reported.
  • This disclosure considers the roles of air velocity, air turbulence and vapour cooling rate in affecting aerosol particle size.
  • a Malvern PANalytical Spraytec laser diffraction system was employed for the particle size measurement.
  • the same coil and wick (1 .5 ohms Ni-Cr coil, 1 .8 mm Y07 cotton wick), the same e-liquid (1 .6% freebase nicotine, 65:35 propylene glycol (PG)/vegetable glycerine (VG) ratio, no added flavour) and the same input power (10W) were used in all experiments.
  • Y07 represents the grade of cotton wick, meaning that the cotton has a linear density of 0.7 grams per meter.
  • Particle sizes were measured in accordance with ISO 13320:2009(E), which is an international standard on laser diffraction methods for particle size analysis. This is particularly well suited to aerosols, because there is an assumption in this standard that the particles are spherical (which is a good assumption for liquid-based aerosols). The standard is stated to be suitable for particle sizes in the range 0.1 micron to 3 mm.
  • Figure 2 shows a schematic perspective longitudinal cross sectional view of an example rectangular tube 1170 with a wick 1162 and heater coil 1164 installed.
  • the location of the wick is about half way along the length of the tube. This is intended to allow the flow of air along the tube to settle before reaching the wick.
  • Figure 3 shows a schematic transverse cross sectional view an example rectangular tube 1170 with a wick 1162 and heater coil 1164 installed.
  • the internal width of the tube is 12 mm
  • the rectangular tubes were manufactured to have same internal depth of 6 mm in order to accommodate the standardized coil and wick, however the tube internal width varied from 4.5 mm to 50 mm.
  • the “tube size” is referred to as the internal width of rectangular tubes.
  • the rectangular tubes with different dimensions were used to generate aerosols that were tested for particle size in a Malvern PANalytical Spraytec laser diffraction system.
  • An external digital power supply was dialled to 2.6A constant current to supply 10W power to the heater coil in all experiments. Between two runs, the wick was saturated manually by applying one drop of e-liquid on each side of the wick.
  • Table 1 shows a list of experiments in this study.
  • the values in “calculated air velocity” column were obtained by simply dividing the flow rate by the intersection area at the centre plane of wick.
  • p is the density of air (1 .225 kg/m 3 ); v is the calculated air velocity in table 1 ; p is the viscosity of air (1 .48 x 10 -5 m 2 /s); L is the characteristic length calculated by:
  • Turbulence intensity was introduced as a quantitative parameter to assess the level of turbulence. The definition and simulation of turbulence intensity is discussed below (see section 3.2).
  • Figures 4A-4D show air flow streamlines in the four devices used in this turbulence study.
  • Figure 4A is a standard 12mm rectangular tube with wick and coil installed as explained in the previous section, with no jetting panel.
  • Figure 4B has a jetting panel located 10mm below (upstream from) the wick.
  • Figure 4C has the same jetting panel 5mm below the wick.
  • Figure 4D has the same jetting panel 2.5mm below the wick.
  • the jetting panel has an arrangement of apertures shaped and directed in order to promote jetting from the downstream face of the panel and therefore to promote turbulent flow.
  • the jetting panel can introduce turbulence downstream, and the panel causes higher level of turbulence near the wick when it is positioned closer to the wick.
  • the four geometries gave turbulence intensities of 0.55%, 0.77%, 1 .06% and 1 .34%, respectively, with Figure 4A being the least turbulent, and Figure 4D being the most turbulent.
  • the experimental set up is shown in Figure 5.
  • the testing used a Carbolite Gero EHA 12300B tube furnace 3210 with a quartz tube 3220 to heat up the air. Hot air in the tube furnace was then led into a transparent housing 3158 that contains the EVP device 3150 to be tested.
  • a thermocouple meter 3410 was used to assess the temperature of the air pulled into the EVP device. Once the EVP device was activated, the aerosol was pulled into the Spraytec laser diffraction system 3310 via a silicone connector 3320 for particle size measurement.
  • pod 1 is the commercially available “myblu optimised” pod ( Figure 6); pod 2 is a pod featuring an extended inflow path upstream of the wick ( Figure 7); and pod 3 is pod with the wick located in a stagnant vaporisation chamber and the inlet air bypassing the vaporisation chamber but entraining the vapour from an outlet of the vaporisation chamber ( Figures 8A and 8B).
  • Pod 1 shown in longitudinal cross sectional view (in the width plane) in Figure 6, has a main housing that defines a tank 160x holding an e-liquid aerosol precursor. Mouthpiece 154x is formed at the upper part of the pod. Electrical contacts 156x are formed at the lower end of the pod. Wick 162x is held in a vaporisation chamber. The air flow direction is shown using arrows.
  • Pod 2 shown in longitudinal cross sectional view (in the width plane) in Figure 7, has a main housing that defines a tank 160y holding an e-liquid aerosol precursor. Mouthpiece 154y is formed at the upper part of the pod. Electrical contacts 156y are formed at the lower end of the pod. Wick 162y is held in a vaporisation chamber. The air flow direction is shown using arrows. Pod 2 has an extended inflow path (plenum chamber 157y) with a flow conditioning element 159y, configured to promote reduced turbulence at the wick 162y.
  • Figure 8A shows a schematic longitudinal cross sectional view of pod 3.
  • Figure 8B shows a schematic longitudinal cross sectional view of the same pod 3 in a direction orthogonal to the view taken in Figure 8A.
  • Pod 3 has a main housing that defines a tank 160z holding an e-liquid aerosol precursor.
  • Mouthpiece 154z is formed at the upper part of the pod. Electrical contacts 156z are formed at the lower end of the pod. Wick 162z is held in a vaporisation chamber. The air flow direction is shown using arrows. Pod 3 uses a stagnant vaporiser chamber, with the air inlets bypassing the wick and picking up the vapour/aerosol downstream of the wick.
  • Air velocity in the vicinity of the wick is believed to play an important role in affecting particle size.
  • the air velocity was calculated by dividing the flow rate by the intersection area, which is referred to as “calculated velocity” in this work. This involves a very crude simplification that assumes velocity distribution to be homogeneous across the intersection area.
  • computational fluid dynamics (CFD) modelling was performed to obtain more accurate velocity values:
  • the CFD model uses a laminar single-phase flow setup.
  • the outlet was configured to a corresponding flowrate
  • the inlet was configured to be pressure-controlled
  • the wall conditions were set as “no slip”.
  • a 1 mm wide ring-shaped domain (wick vicinity) was created around the wick surface, and domain probes were implemented to assess the average and maximum magnitudes of velocity in this ring-shaped wick vicinity domain.
  • the CFD model outputs the average velocity and maximum velocity in the vicinity of the wick for each set of experiments carried out in section 2.1 .
  • the outcomes are reported in Table 2.
  • Turbulence modelling is a quantitative value that represents the level of turbulence in a fluid flow system. It is defined as the ratio between the root-mean-square of velocity fluctuations, u' , and the
  • turbulence intensity represents higher levels of turbulence.
  • turbulence intensity below 1% represents a low-turbulence case
  • turbulence intensity between 1% and 5% represents a medium-turbulence case
  • turbulence intensity above 5% represents a high-turbulence case.
  • turbulence intensity was obtained from CFD simulation using turbulent single-phase setup in COMSOL Multiphysics.
  • the outlet was set to 1 .3 Ipm
  • the inlet was set to be pressure-controlled, and all wall conditions were set to be “no slip”.
  • Turbulence intensity was assessed within the volume up to 1 mm away from the wick surface (defined as the wick vicinity domain).
  • the turbulence intensities are 0.55%, 0.77%, 1 .06% and 1 .34%, respectively, as also shown in Figures 4A-4D.
  • the cooling rate modelling involves three coupling models in COMSOL Multiphysics: 1 ) laminar two- phase flow; 2) heat transfer in fluids, and 3) particle tracing.
  • the model is setup in three steps:
  • Laminar mixture flow physics was selected in this study.
  • the outlet was configured in the same way as in section 3.1 .
  • this model includes two fluid phases released from two separate inlets: the first one is the vapour released from wick surface, at an initial velocity of 2.84 cm/s (calculated based on 5 mg total particulate mass over 3 seconds puff duration) with initial velocity direction normal to the wick surface; the second inlet is air influx from the base of tube, the rate of which is pressure-controlled.
  • the inflow and outflow settings in heat transfer physics was configured in the same way as in the two- phase flow model.
  • the air inflow was set to 25 °C
  • the vapour inflow was set to 209 °C (boiling temperature of the e-liquid formulation).
  • the heat transfer physics is configured to be two-way coupled with the laminar mixture flow physics.
  • the above model reaches steady state after approximately 0.2 second with a step size of 0.001 second.
  • the particle tracing physics has one-way coupling with the previous model, which means the fluid flow exerts dragging force on the particles, whereas the particles do not exert counterforce on the fluid flow. Therefore, the particles function as moving probes to output vapour temperature at each timestep.
  • the model outputs average vapour temperature at each time steps.
  • a MATLAB script was then created to find the time step when the vapour cools to a target temperature (50°C or 75°C), based on which the vapour cooling rates were obtained (Table 3).
  • Particle size measurement results for the rectangular tube testing are shown in Table 4.
  • Table 4 For every tube size and flow rate combination, five repetition runs were carried out in the Spraytec laser diffraction system. The Dv50 values from five repetition runs were averaged, and the standard deviations were calculated to indicate errors, as shown in Table 4.
  • the particle size (Dv50) experimental results are plotted against calculated air velocity in Figure 9.
  • the graph shows a strong correlation between particle size and air velocity.
  • Different size tubes were tested at two flow rates: 1 .3 Ipm and 2.0 Ipm. Both groups of data show the same trend that slower air velocity leads to larger particle size. The conclusion was made more convincing by the fact that these two groups of data overlap well in Figure 9: for example, the 6mm tube delivered an average Dv50 of 1 .697 pm when tested at 1 .3 Ipm flow rate, and the 8mm tube delivered a highly similar average Dv50 of 1 .646 gm when tested at 2.0 Ipm flow rate, as they have similar air velocity of 0.71 and 0.72 m/s, respectively.
  • Figure 10 shows the results of three experiments with highly different setup arrangements: 1 ) 5mm tube measured at 1 .4 Ipm flow rate with Reynolds number of 155; 2) 8mm tube measured at 2.8 Ipm flow rate with Reynolds number of 279; and 3) 20mm tube measured at 8.6 Ipm flow rate with Reynolds number of 566. It is relevant that these setup arrangements have one similarity: the air velocities are all calculated to be 1 m/s.
  • Figure 10 shows that, although these three sets of experiments have different tube sizes, flow rates and Reynolds numbers, they all delivered similar particle sizes, as the air velocity was kept constant. These three data points were also plotted out in Figure 9 (1 m/s data with star marks) and they tie in nicely into particle size-air velocity trendline.
  • the particle size measurement data were plotted against the average velocity (Figure 1 1 ) and maximum velocity (Figure 12) in the vicinity of the wick, as obtained from CFD modelling.
  • the data in these two graphs indicates that in order to obtain an aerosol with Dv50 larger than 1 pm, the average velocity should be less than or equal to 1 .2 m/s in the vicinity of the wick and the maximum velocity should be less than or equal to 2.0 m/s in the vicinity of the wick.
  • the average velocity should be less than or equal to 0.6 m/s in the vicinity of the wick and the maximum velocity should be less than or equal to 1 .2 m/s in the vicinity of the wick.
  • typical commercial EVP devices deliver aerosols with Dv50 around 0.5 pm, and there is no commercially available device that can deliver aerosol with Dv50 exceeding 1 pm. It is considered that typical commercial EVP devices have average velocity of 1 .5-2.0 m/s in the vicinity of the wick.
  • the graph suggests a correlation between particle size and turbulence intensity, that lower turbulence intensity is beneficial for obtaining larger particle size. It is noted that when turbulence intensity is above 1% (medium-turbulence case), there are relatively large measurement fluctuations. In Figure 13, the tube with a jetting panel 10mm below the wick has the largest error bar, because air jets become unpredictable near the wick after traveling through a long distance.
  • Figure 14 shows the high temperature testing results. Larger particle sizes were observed from all 3 pods when the temperature of inlet air increased from room temperature (23°C) to 50 °C. When the pods were heated as well, two of the three pods saw even larger particle size measurement results, while pod 2 was unable to be measured due to significant amount of leakage.
  • laminar flow allows slow and gradual mixing between cold air and hot vapour, which means the vapour can cool down in slower rate when the airflow is laminar, resulting in larger particle size.
  • the data in these graphs indicates that in order to obtain an aerosol with Dv50 larger than 1 pm, the apparatus should be operable to require more than 16 ms for the vapour to cool to 50°C, or an equivalent (simplified to an assumed linear) cooling rate being slower than 10 °C/ms. From an alternative viewpoint, in order to obtain an aerosol with Dv50 larger than 1 pm, the apparatus should be operable to require more than 4.5 ms for the vapour to cool to 75°C, or an equivalent (simplified to an assumed linear) cooling rate slower than 30 °C/ms.
  • the apparatus should be operable to require more than 32 ms for the vapour to cool to 50°C, or an equivalent (simplified to an assumed linear) cooling rate being slower than 5 °C/ms.
  • the apparatus in order to obtain an aerosol with Dv50 of 2 pm or larger, should be operable to require more than 13 ms for the vapour to cool to 75°C, or an equivalent (simplified to an assumed linear) cooling rate slower than 10 °C/ms.
  • particle size (Dv50) of aerosols generated in a set of rectangular tubes was studied in order to decouple different factors (flow rate, air velocity, Reynolds number, tube size) affecting aerosol particle size. It is considered that air velocity is an important factor affecting particle size - slower air velocity leads to larger particle size. When air velocity was kept constant, the other factors (flow rate, Reynolds number, tube size) has low influence on particle size.

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Abstract

L'invention concerne un appareil de substitution pour fumeur (150) avec une entrée d'air ; un générateur d'aérosol pour générer un aérosol à partir d'un précurseur d'aérosol destiné à être inhalé par un utilisateur ; une sortie formée au niveau d'un embout buccal ; et un conduit de distribution d'aérosol (602) s'étendant en aval depuis le générateur d'aérosol jusqu'à la sortie. Une voie d'écoulement d'air s'étend entre l'entrée d'air et la sortie et le long du conduit de distribution d'aérosol pour transporter l'aérosol vers l'utilisateur. En fonctionnement, le générateur d'aérosol chauffe le précurseur d'aérosol pour former un précurseur d'aérosol vaporisé, le précurseur d'aérosol vaporisé étant transporté dans l'écoulement d'air et se condensant pour former des gouttelettes d'aérosol. La voie d'écoulement d'air et le générateur d'aérosol sont conçus pour commander les caractéristiques d'écoulement d'air au niveau du générateur d'aérosol pour fournir un aérosol ayant des caractéristiques de taille de particule prédéterminées à une première position le long de la voie d'écoulement d'air dans le conduit de distribution d'aérosol. L'appareil comprend en outre un perturbateur d'écoulement d'air (610) disposé dans le conduit de distribution d'aérosol (602) au niveau ou en aval de la première position, le perturbateur d'écoulement d'air (610) provoquant une interruption de l'écoulement d'air en aval du perturbateur d'écoulement d'air et par conséquent le refroidissement des gouttelettes d'aérosol. Le perturbateur d'écoulement d'air comprend une saillie s'étendant dans la voie d'écoulement d'air latéralement à partir d'une paroi latérale (612) du conduit de distribution d'aérosol (602). Un procédé de fonctionnement de l'appareil est également divulgué.
EP22783450.4A 2021-09-28 2022-09-09 Appareil de substitution pour fumeur Pending EP4408223A1 (fr)

Applications Claiming Priority (2)

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EP21199533 2021-09-28
PCT/EP2022/075189 WO2023052094A1 (fr) 2021-09-28 2022-09-09 Appareil de substitution pour fumeur

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Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL2408494T3 (pl) * 2009-03-17 2021-11-02 Philip Morris Products S.A. Układ do wytwarzania aerozolu na bazie tytoniu
EP2319334A1 (fr) * 2009-10-27 2011-05-11 Philip Morris Products S.A. Système de fumage ayant une partie de stockage de liquide
UA120165C2 (uk) * 2013-07-25 2019-10-25 Олтріа Клайєнт Сервісиз Ллк Електронний виріб для вейпінгу
WO2021053214A1 (fr) * 2019-09-20 2021-03-25 Nerudia Limited Appareil de substitution pour fumeur

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