EP4293148A1 - Couche non tissée comprenant un réseau de fibres cellulosiques régénérées sensiblement continues - Google Patents

Couche non tissée comprenant un réseau de fibres cellulosiques régénérées sensiblement continues Download PDF

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Publication number
EP4293148A1
EP4293148A1 EP22179266.6A EP22179266A EP4293148A1 EP 4293148 A1 EP4293148 A1 EP 4293148A1 EP 22179266 A EP22179266 A EP 22179266A EP 4293148 A1 EP4293148 A1 EP 4293148A1
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Prior art keywords
nonwoven layer
nonwoven
sample
fibers
layer according
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EP22179266.6A
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German (de)
English (en)
Inventor
Berndt KÖLL
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Lenzing AG
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Lenzing AG
Chemiefaser Lenzing AG
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Priority to EP22179266.6A priority Critical patent/EP4293148A1/fr
Publication of EP4293148A1 publication Critical patent/EP4293148A1/fr
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    • D—TEXTILES; PAPER
    • D04—BRAIDING; LACE-MAKING; KNITTING; TRIMMINGS; NON-WOVEN FABRICS
    • D04H—MAKING TEXTILE FABRICS, e.g. FROM FIBRES OR FILAMENTARY MATERIAL; FABRICS MADE BY SUCH PROCESSES OR APPARATUS, e.g. FELTS, NON-WOVEN FABRICS; COTTON-WOOL; WADDING ; NON-WOVEN FABRICS FROM STAPLE FIBRES, FILAMENTS OR YARNS, BONDED WITH AT LEAST ONE WEB-LIKE MATERIAL DURING THEIR CONSOLIDATION
    • D04H3/00—Non-woven fabrics formed wholly or mainly of yarns or like filamentary material of substantial length
    • D04H3/013—Regenerated cellulose series

Definitions

  • the present disclosure relates to the field of cellulosic nonwoven materials and especially to nonwoven materials having specific wicking properties.
  • Such nonwoven materials can, for example, be used as fluid transporting layers in lateral flow assay kits.
  • the current disclosure relates to improvements concerning the production and use of nonwoven layers comprising a network (also called "web") of substantially continuous regenerated cellulosic fibers. More specifically, the current disclosure relates to novel nonwoven layers that are produced according to the so-called solution-blown process and have improved wicking properties.
  • Cellulosic fibers can be produced by various processes.
  • a lyocell fiber is spun from a lyocell spinning solution comprising cellulose dissolved in N-methyl morpholine N-oxide (NMMO) by a meltblown process, in principle known from e.g. EP 1093536 B1 , EP 2013390 B1 and EP 2212456 B1 .
  • NMMO N-methyl morpholine N-oxide
  • meltblown refers to a process that is similar or analogous to the process used for the production of synthetic thermoplastic fibers (filaments are extruded under pressure through nozzles and stretched to required degree by high velocity/high temperature extension air flowing substantially parallel to the filament direction), even though the cellulose is dissolved in solution (i.e. not a molten thermoplastic) and the spinning & air temperatures are only moderately elevated. Therefore the term “solution blown” may be even more appropriate here instead of the term “meltblown” which has already become somewhat common for these kinds of technologies.
  • the term “meltblown” is used as a generic term, independent of the fiber material and the term “solution blown” is used for the production of cellulosic nonwovens from lyocell spinning solution.
  • the fibers are contacted with a nonsolvent such as water (or water/NMMO mixture) by spraying, after extrusion but before web formation.
  • a nonsolvent such as water (or water/NMMO mixture) by spraying, after extrusion but before web formation.
  • the fibers are subsequently taken up on a moving foraminous support to form a nonwoven web, washed and dried.
  • Freshly-extruded lyocell solution which will contain only, for example, 5-15% cellulose, behaves in a similar way to 'sticky' and deformable thermoplastic filaments. Causing the freshly-spun filaments to contact each other while still swollen with solvent and with a 'sticky' surface under even low pressure will cause merged filament bonding, where molecules from one filament mix irreversibly with molecules from a different filament. Once the solvent is removed and coagulation of filaments completed, this type of bonding is impossible.
  • LFA Lateral flow assays
  • CAGR compound average growth rate
  • An LFA is a portable strip in a plastic housing that consists of several parts.
  • the sample pad is the first area to get in contact with the sample fluid. Its major purpose is to allow the liquid to flow through the test kit reasonably fast and in a continuous way. Through its wicking performance it guides the sample to the so called test membrane via a conjugate pad.
  • the membrane is the most critical element in any LFA strip. It contains the test result line as well as the control line. Nitrocellulose is most commonly selected as membrane carrier material. An absorbent pad absorbs excess sample fluid.
  • sample pads and absorbent pads cellulose containing products like laboratory papers are being used.
  • the papers are selected for they increased and constant wicking speed as well as for trouble free processing like in slitting processes for cutting the narrow strips.
  • special nonwoven layers comprising glass fibers and/or synthetic fibers.
  • the present disclosure provides novel cellulosic nonwoven layers having advantageous wicking rates and can be used, inter alia, as a sample fluid transporting layer in a lateral flow assay. Further the present disclosure provides lateral flow assays comprising the nonwoven layer. Still further the present disclosure provides methods for use of the nonwoven layer an/or the lateral flow assay.
  • the present document discloses a nonwoven layer comprising a network of substantially continuous regenerated cellulosic fibers which has a wicking time of between 5 and 50 s/40mm, preferably between 8 and 20 s/40mm, wherein the wicking time is determined by measuring the time it takes for the water to reach a level of 40 mm above liquid surface in a test arrangement according to Harmonized Nonwovens Standard Procedure NWSP 010.1.R0 (15).
  • Nonwoven materials that have a fast wicking time are advantageous for a plurality of uses, for example a fluid transporting layer in lateral flow assay test kits. It has been surprisingly found that nonwoven layers according to the present disclosure exhibit wicking times that exceed the wicking times of laboratory papers which are currently used in the field of lateral flow assays. The performance of the nonwoven materials described herein even compares with special high-tech wicking materials comprising microfiber glass and/or polyester fibers. Still, the nonwoven material according to the present disclosure can be made of 100 percent cellulosic material and therefore is ecological and biodegradable.
  • substantially continuous regenerated cellulosic fibers refers to fibers that are produced in a continuous spinning process, wherein the fibers are not cut into staple fibers.
  • the production of the substantially continuous regenerated cellulosic fibers comprises a solution blown process.
  • the measurement of the wicking time can preferably be performed according to the test arrangement described in Harmonized Nonwovens Standard Procedure NWSP 010.1.R0 (15), wherein the time it takes for the water to reach a level of 40 mm above water surface is accurately measured as the wicking time. It should be noted that similar internal or official standards can be used for the measurement of the wicking time and/or the wicking rate, as long as they do not significantly alter the measurement results and allow for an assured determination whether or not the measured property falls into the claimed range.
  • the nonwoven layer according to the present disclosure can have a basis weight of between 15 g/m 2 and 200 g/m 2 , preferably between 20 g/m 2 and 100 g/m 2 . It has been surprisingly found that the nonwoven layers according to the present disclosure can be used at a lower basis weight compared to currently used wicking materials and still produce the required performance. This, inter alia, reduces material costs and reduces the environmental load.
  • the basis weight also designated as "mass per unit area” can preferably be determined according to Nonwoven Standard Procedure NWSP 130.1.R0 (15).
  • the nonwoven layer can have a porosity of between 50 % and 90 %, preferably between 80 and 90%. This allows for a high liquid uptake and good wicking speed at a low basis weight.
  • the porosity of a material is defined as the fraction of the volume of voids over the total volume of the material and can preferably be measured by mercury porosimetry according to ISO 15901-1:2016.
  • the nonwoven layer according to the present disclosure can have a specific pore volume of between about 2 cm 3 /g and about 5 cm 3 /g, preferably between about 3 cm 3 /g and about 4 cm 3 /g.
  • the specific pore volume can preferably be determined according to ISO 15901-1:2016.
  • the nonwoven layer can have a median pore size of between 50 and 120 ⁇ m, preferably between 80 and 100 ⁇ m.
  • the pore size and pore size distribution can be adjusted to the specific wicking fluid, the nonwoven layer is produced for.
  • the pore size distribution can preferably be measured via Hg-Porosimetry according to ISO 15901-1:2016.
  • a size distribution with a median pore size in the range specified above can be preferred for essentially aqueous substances.
  • the pore size, specific pore volume and/or porosity of the nonwoven layer can be adjusted by several production parameters, especially the stretching air pressure, the amount of coagulation liquid, the extrusion speed (which can be indicated as the mass of spinning solution extruded through each spinning hole in a given time, e.g. g/min), the amount and density of holes and the hole diameters of the spinneret, the distance between the spinneret and the support, where the nonwoven layer is formed. Generally, a higher amount of coagulation within the air gap between the Spinneret and the support will produce a higher pore size.
  • the fibers in the nonwoven layer can be finish free.
  • "Finish free”, as the term is used herein, denotes fibers that have not been subjected to a finishing step and therefore are free of finishing agents.
  • the nonwoven layer can also be produced with production methods that ensure that the layer is essentially free of substances that could affect any test results in a lateral flow assay.
  • the nonwoven layer can be essentially free of copper and/or nickel.
  • operating fluids in particular lyocell spinning solution, coagulation fluid, washing liquor, gas flow, etc.
  • the cellulosic fibers according to the present disclosure may be of high quality and may substantially consist of pure microfibrillar cellulose.
  • the absence of any mentionable heavy metal impurities in the manufacturing process prevents highly undesired decomposition of involved media (in particular of the lyocell spinning solution) and therefore allows to obtain highly reproducible and highly pure cellulose fibers that are biodegradable.
  • essentially free of copper and/or nickel denotes that these substances are maximally present in practically negligible amounts.
  • a copper contents of less than 5 ppm and/or a nickel contents of less than 3 ppm is practically negligible in most cases and therefore can be considered as essentially free of copper and/or nickel, respectively.
  • the nonwoven layer can be directly manufactured from lyocell spinning solution in a solution blown process.
  • a nonwoven layer forms a network of substantially endless regenerated cellulosic fibers.
  • the nonwoven layer can easily, yet reliably be produced and can be provided with a very homogeneous pore size distribution.
  • the cellulosic fibers can further improve the liquid wicking and liquid absorbency properties.
  • the nonwoven layer may contain essentially only cellulose, thus, showing good biodegradability.
  • the cellulosic nonwoven layer, directly manufactured from lyocell spinning solution can be manufactured according to a variant of a solution blown process (also called spunlaid nonwoven process), e.g.
  • Such a nonwoven layer formed by the above mentioned process may thus provide good absorbency, fast wicking, fast liquid uptake, good spread-ability of liquid, enhanced dimensional stability (wet and dry), biodegradability and sustainability; all without the need of adding binders or chemicals.
  • the nonwoven layer can also be combined with composite materials, such as pulp, preferably derived from wood, staple fibers, binders, wicking controlling agents or the like.
  • Wicking controlling agents are substances that are applied to influence the wicking speed of the nonwoven material. For example by changing the hydrophilic properties of the fibers, the wicking properties of the nonwoven material can be changed to a certain extent.
  • Pulp can, for example, be applied to the solution blown nonwoven material after the formation of the nonwoven layer via processes such as wetlaid or airlaid. Such processes are per se known in the art.
  • the composite material can subsequently be treated by a hydroentanglement-step to improve the bonding of the pulp and the nonwoven layer.
  • the cellulosic fibers in the nonwoven layer can be multibonded by merging, hydrogen bonding and/or physically intermingling.
  • the dimensional stability of the nonwoven layer may be improved, which also improves the machinability of the nonwoven layer.
  • the fibers of the nonwoven layer can have diameters ranging from 1 ⁇ m to 250 ⁇ m, preferably from 2 ⁇ m to 75 ⁇ m.
  • This scope includes cellulosic materials that are made according to a meltblown process. In this case the larger diameters in particular belong to merging points.
  • Most of the suitable meltblown materials according to the present disclosure may show fiber diameters of up to 75 ⁇ m only, however materials with the larger diameters may be suitable, as well.
  • the present document discloses the use of a nonwoven layer as disclosed herein for the production of a sample fluid transporting layer in a lateral flow assay.
  • a nonwoven layer as disclosed herein for the production of a sample fluid transporting layer in a lateral flow assay.
  • the novel nonwoven layer according to the present disclosure can be advantageously used for either a fluid transporting layer in an lateral flow assay, particularly as a material for the production of the sample pad and/or the absorbent pad, but also as a material for the production of the conjugation pad and/or even the test membrane.
  • the present document discloses a lateral flow assay comprising a housing with at least one sample port and at least one display port and at least one sample fluid transporting layer, wherein the at least one sample fluid transporting layer comprises at least one nonwoven layer according to an embodiment of the present disclosure.
  • a lateral flow assay can be produced according to high-quality standards using up to 100% environmental-friendly or even biodegradable materials.
  • the lateral flow assay can have at least one fluid transporting layer, the fluid transporting layer comprising at least one of a sample pad, a conjugate pad, a test membrane and/or an absorbent pad, wherein at least one of the sample pad, the conjugate pad, the test membrane and/or the absorbent pad comprises at least one nonwoven layer according to any of the embodiments disclosed herein.
  • Such a lateral flow assay can use the beneficial properties of the nonwoven layers disclosed herein.
  • biodegradable or compostable materials also for the production of the housing of the lateral flow assay, environmental-friendly test assay kits can be provided that avoid the use of single-use plastic materials.
  • the assays can therefore be fully biodegradable or even compostable.
  • the lateral flow assay can be made using a biodegradable or compostable material selected from a list comprising biopolymers such as cellulose, polylactic acid (PLA), cellulose acetate, polyhydroxyalkanoate (PHA) or the like.
  • Fig. 1 shows a lateral flow assay 1 having a plurality of sample fluid transportation layers 8 that are arranged in a housing 2.
  • the housing 2 has, on an upper side 3 of it, several openings, namely at least one sample port 4 and at least one display port 5.
  • the display port 5 can have several separated sections, for example a result display port 6 and a test display port 7 as shown in Fig. 1 .
  • a result display port 6 and a test display port 7 as shown in Fig. 1 .
  • different layouts of the housing 2 and the openings are possible, as is known by the skilled practitioner.
  • At least one sample fluid transporting layer 8 is arranged, which takes up a sample fluid at the at least one sample port 4 and transports the sample fluid by force of a wicking effect to the display port 5, where the sample fluid interacts with at least one marker material.
  • a first marker material interacts with a test result line 13, which visibly changes its color in case of a positive test result, and another marker material interacts with a control line 14 that visibly changes color when the sample fluid is present in an adequate amount.
  • the sample fluid transporting layer 8 usually has several parts that have a specific purpose.
  • the transporting layer 8 can comprise a sample pad 9, a conjugation pad 10, a test membrane 11 and an absorbent pad 12.
  • the sample pad 9 receives the sample fluid and acts as the first stage of the absorption process.
  • the sample pad 9 can, in some cases, also contain a filter (not shown), to ensure the accurate and controlled flow of the sample.
  • the sample fluid moves along the sample pad 9 to reach the conjugate pad 10.
  • the conjugate pad 10 comprises conjugated labels and antibodies (marker materials) that will bind to a target, if it is present in the sample fluid.
  • the conjugate pad 10 also comprises control-antibodies that are specific for the sample fluid but not specific for the target. If the target is present, the immobilized conjugated antibodies and labels will bind to the target and continue to migrate along the transporting layer 8 with the sample fluid and move to the test membrane 11.
  • the test membrane 11 usually is a nitrocellulose membrane comprising lines with binding reagents that form at least one test result line 13 and one control line 14. As the sample moves along the test membrane 11, the binding reagents situated on the test membrane 11 will bind to the target at the test line and a colored line will form. Depending on the quantity of the target present, the density of the line will vary. Some assays can also provide for a quantification of the target concentration.
  • the absorbent pad 12 After the sample fluid has passed through the test membrane 11 it reaches the absorbent pad 12 which will absorb the excess sample fluid.
  • the properties of the absorbent pad has an impact on the volume of sample fluid the test can incorporate.
  • the properties of the materials that are used for the sections of the fluid transporting layer 8 are very important. Especially for the two pads that are not directly involved in the biochemical processes, namely the sample pad 9 and the absorbent pad 12, but also for the conjugation pad 10 and the test membrane 11, a good wicking rate, a proper fluid absorption capacity and a low basis weight is desired. Further, the materials should be available at a reasonable price and must not interfere with the biochemical properties of the sample fluid.
  • Fig. 2 and 3 show microscopic images of nonwoven layers according to the present disclosure.
  • the nonwoven layers have been produced in a solution blown process from lyocell solution as a network of substantially continuous regenerated cellulosic fibers.
  • Fig. 2 and 3 have been taken with an electron microscope Thermo Fisher Scientific - Quanta 450.
  • the depicted surface areas are identical in both Fig. 2 and 3 and each have a dimension of about 800 ⁇ m x 550 ⁇ m.
  • Fig. 2 shows the structure of a nonwoven layer of rather fine substantially continuous regenerated cellulosic fibers.
  • the picture was taken from a piece of a nonwoven layer herein designated as "Sample A".
  • the fiber diameters are mostly ranging from about 2 ⁇ m to about 8 ⁇ m, wherein most of the fibers are in a lower range of about 2 ⁇ m to 4 ⁇ m and only few of the fibers are stronger that that.
  • Several bonding sites can be seen where different fibers have bonded to form nodes and also some bigger interconnected structures are to be identified. Nonetheless, the amount of merging and interfiber-bonding was kept rather low during production so that the route of the single fibers can be clearly seen in most parts of the nonwoven.
  • Fig. 3 shows a picture of a nonwoven layer according to the present disclosure having a coarser structure than the one shown in Fig. 2 .
  • the picture was taken from a piece of a nonwoven layer herein designated as "Sample B".
  • Most fibers in the nonwoven layer shown in Fig. 3 have diameters ranging from about 2 ⁇ m to about 8 ⁇ m, but in this case many of the fibers are in the higher range of about 4 ⁇ m to about 8 ⁇ m.
  • the structure of Sample B is less dense compared to Sample A, which results in a higher mean pore size.
  • a higher amount of inter-fiber bonding was allowed to take place. This results in a rather course and stable nonwoven layer, generally having larger pore sizes.
  • the fibers show a strong filament bonding at many bonding sites which leads to bonded structures that are significantly broader than the single fibers and appear in the picture as nodes or even extensive lumps. Nonetheless, also in this case the nonwoven layer was produced to have a very uniform pore-size distribution.
  • nonwovens can be produced that have remarkable wicking properties already at very low basis weight and a rather thin thickness.
  • the wicking properties can be assessed by either the wicking rate (i.e. the distance that a liquid travelled vertically upwards along the fabric in a given time) or the wicking time (i.e. the time it takes for a liquid to reach a specified distance).
  • the wicking rate i.e. the distance that a liquid travelled vertically upwards along the fabric in a given time
  • the wicking time i.e. the time it takes for a liquid to reach a specified distance.
  • the wicking time over a distance of 40 mm is a good quality indicating factor and should be as short as possible.
  • the nonwoven layers can be produced with a very high degree of homogeneity, which means that the pore size distribution and the filament diameter distribution does not deviate much across the whole extension of the nonwoven layer. This makes the resulting quality of the nonwoven layer highly reproducible and the production parameter can be easily tailored to the specific needs.
  • the nonwoven layer is mostly free of anomalies, such as excessively larges pores or even holes. Such anomalies can often be seen in common nonwoven materials, for example due to a hydroentanglement treatment.
  • the viscosity of the spinning solution can be altered.
  • a higher viscosity generally leads to thicker fibers and also the coagulation speed changes.
  • the viscosity has to be within the acceptable parameters of the spinneret.
  • the viscosity also has effects on the tensile strength and the brittleness of the fibers.
  • the size, particularly the width and the thickness of the nonwoven layer can be controlled.
  • the spinneret dimensions i.e. the nozzle diameter and form and/or the distance between single nozzles influence the homogeneity of the nonwoven layer (amongst several other effects).
  • extrusion speed Another important parameter that has an effect on numerous properties is the extrusion speed. It directly alters the basis weight of the nonwoven layer, but also has effects on other factors, such as the coagulation or the multibonding of the fibers.
  • extension airflow can be adjusted, which (inter alia) alters the fiber stretch and the entanglement of the fibers.
  • the coagulation of the fibers in the air-gap i.e. before the formation of the nonwoven layer
  • a low amount of coagulation spray leaves the fibers in a less coagulated state so that they are still "sticky" at the time of formation of the nonwoven layer, which induces a high amount of interbonding sites.
  • the air gap distance between the spinneret, where the fibers are extruded, and the foraminous support, where the fibers are collected in form of the nonwoven layer has an effect on the entanglement of the fibers.
  • the fibers have more time to swirl and entangle with adjacent fibers when the air gap is increased, which leads to a high degree of entanglement.
  • the coagulation is influenced by the air gap distance.
  • an oversized air gap could have a negative impact on the homogeneity of the nonwoven layer.
  • the speed of the foraminous support mainly alters the basis weight of the nonwoven layer but also has several effects on the web-formation.
  • the post processing of the nonwoven layer can be used to alter the quality and properties of the nonwoven layer.
  • the main parameters for controlling the wicking rate of a so produced nonwoven layer are the filament stretch through stretching air pressure (which also affects the diameter distribution of the filaments in the nonwoven layer) and the amount of coagulation liquid used to coagulate the filaments in the air gap after the spinneret.
  • a high filament stretch through high stretching air pressure at the spinneret creates fine filaments.
  • a high amount of coagulation liquid is needed.
  • Finer filaments generally go in hand with better wicking properties. Therefore, the wicking properties can be improved (i.e. higher wicking rate an lower wicking time) by raising the stretching air pressure and the amount of coagulation liquid.
  • the nonwoven layers that are made by the solution blown process can be produced 100 % biodegradable or even compostable which, for example, allows for the production of ecological lateral flow assays.
  • biodegradable materials for the production of the housing and the other parts of the lateral flow assay a completely biodegradable or even compostable lateral flow assay can be produced.
  • sample A and Sample B Two products comprising a nonwoven layer were manufactured by the applicant using the solution blown process described herein.
  • the products were designed to produce a highly porous 3-dimensional web ("Sample A and Sample B").
  • the basis weight of the nonwovens layer of Sample A was adjusted to 70 g/m 2 and the basis weight of the nonwoven layer of Sample B was adjusted to 68 g/m 2 .
  • the solution blown nonwovens of the samples were created to give a high relative surface area whilst maintaining a product surface that is virtually free of mechanical defects like irregularly large holes.
  • Sample A a high amount of stretching air pressure and coagulation liquid was set to produce a nonwoven layer with a very fine fiber structure.
  • Sample B was produced with a lower amount of stretching air pressure and coagulation liquid.
  • the stretching air pressure of Sample A was about 2 times higher and the coagulation water flow was about 1.5 times higher compared to Sample B.
  • the pore size distribution of Sample A was measured via Hg-Porosimetry according to ISO 15901-1:2016, using a Quantachrome Poremaster 60-GT, 3P Instruments GmbH & Co KG.
  • the theoretical basis for the method is the so called Washburn equation, which represents the relation between pore filling (intrusion) and pore emptying (extrusion) as a function of the applied pressure through a non compressible, non-wetting liquid (Mercury).
  • the nonwoven layer according to Sample A showed a uniform pore size distribution with a median pore diameter at 93 ⁇ m.
  • the overall nonwoven thickness was measured to be 490 ⁇ m, which indicates the average pore size constituting almost 20% of the overall nonwoven caliper.
  • Sample A had a specific pore volume of 3.731 cm 3 /g, a raw density of 0,23 g/cm 3 and a prosity of 85.5 %.
  • a normalized volume curve is obtained, where the intruded volume is shown as a function of pore size. Since larger pores are intruded prior to smaller pores, the axis of ordinates shows the pores size decreasing from left to right.
  • the pore size distribution curve is being calculated by differentiation of a normalized volume graph. The result of the pore size distribution measurement is depicted in Fig. 4 .
  • the axis of abscissas refers to the pore size (i.e. the diameter) on a logarithmical scale, the axis of ordinates shows the relative frequency of a specific pore size.
  • Fig. 4 evidence that the average pore size of Sample A is considerably larger (about 4 times) than for instance of graphical paper.
  • the pore size in paper products is, for example, described in " The pore radius distribution in paper. Part I: The effect of formation and grammage", Dodson, C.T.J., Handley, Am Oba, Y, Sampson, W. Appita Journal, 2002, 56 .
  • Samples A and B were subjected to a liquid uptake speed tests ("nonwoven absorption") according to Harmonized Nonwovens Standard Procedure NWSP 010.1.R0 (15) [EN]. The results were compared with a standard commercial laboratory paper sample ("comparison") which were tested according to the same protocol. The wicking rates after 300 s were measured for the samples and the comparison. Also, for the Samples A and B the wicking rates after 10 s, 30 s and 60 s were measured. Further, the time required to pass a mark that was arranged 40mm above the water surface (i.e. the "40 mm wicking time") was also recorded. It is to be noted that the measurement of the 40 mm wicking time is not explicitly described in NWSP 010.1.R0, but can be easily implemented according to this protocol.
  • Sample A and B were done in machine direction (MD) and in cross direction (CD).
  • the results show that the wicking times of the tested samples A and B are about 5 to 10 times faster than the wicking time of conventional laboratory paper. Also, the wicking rate at 300 s in CD is about twice the amount of the laboratory paper and the wicking rate at 300 s in MD is even better.
  • the tested nonwoven product showed remarkable and surprisingly good wicking properties, both in machine direction and cross-direction. Due to its microstructure, the product exhibits a fast wicking performance and time-constant fluid transportation capabilities. This allows, inter alia, for the use of the product as a fluid transporting layer of lateral flow assays, where high and reliable wicking rates are desired. Consequently, the innovation of the novel nonwoven layer according to the present disclosure enables the development of fast, specific and reliable new diagnostic tests.
  • the wicking time of the nonwoven layer can be adjusted to a wicking time of between 5 and 50 s/40mm, preferably between 8 and 20 s/40mm by adjusting the stretching air pressure and the amount of coagulation liquid, wherein an increase in air pressure and/or coagulation liquid reduces the wicking time of the nonwoven layer.

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  • Nonwoven Fabrics (AREA)
EP22179266.6A 2022-06-15 2022-06-15 Couche non tissée comprenant un réseau de fibres cellulosiques régénérées sensiblement continues Pending EP4293148A1 (fr)

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Citations (9)

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Publication number Priority date Publication date Assignee Title
EP1093536B1 (fr) 1998-06-05 2003-10-01 Tencel Limited Non-Tisse et procede servant a le fabriquer
WO2007124521A1 (fr) 2006-04-28 2007-11-08 Lenzing Aktiengesellschaft Produits hydro-enchevêtrés comprenant des fibres de cellulose
EP2212456B1 (fr) 2007-11-07 2015-07-22 Lenzing Aktiengesellschaft Procédé de production d'un produit hydrolié comprenant des fibres de cellulose
JP2017215284A (ja) * 2016-06-02 2017-12-07 旭化成株式会社 イムノクロマトグラフィー試験装置
WO2018071928A1 (fr) 2016-10-21 2018-04-26 Lenzing Ag Procédé et dispositif de formation de bandes cellulosiques directement formées
WO2018184038A1 (fr) 2017-04-03 2018-10-11 Lenzing Ag Non-tissé de cellulose à filament continu fabriqué selon de multiples techniques de liaison
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