EP3972671A1 - Procédé de détermination de paramètres de seringue au moyen d'un pousse-seringue, et dispositifs - Google Patents

Procédé de détermination de paramètres de seringue au moyen d'un pousse-seringue, et dispositifs

Info

Publication number
EP3972671A1
EP3972671A1 EP20727962.1A EP20727962A EP3972671A1 EP 3972671 A1 EP3972671 A1 EP 3972671A1 EP 20727962 A EP20727962 A EP 20727962A EP 3972671 A1 EP3972671 A1 EP 3972671A1
Authority
EP
European Patent Office
Prior art keywords
syringe
position value
syringe pump
value
steps
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP20727962.1A
Other languages
German (de)
English (en)
Inventor
Michael TANNEBERG
Thomas Nuernberger
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fresenius Medical Care Deutschland GmbH
Original Assignee
Fresenius Medical Care Deutschland GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fresenius Medical Care Deutschland GmbH filed Critical Fresenius Medical Care Deutschland GmbH
Publication of EP3972671A1 publication Critical patent/EP3972671A1/fr
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
    • A61M5/1452—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons
    • A61M5/14546—Front-loading type injectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3621—Extra-corporeal blood circuits
    • A61M1/367—Circuit parts not covered by the preceding subgroups of group A61M1/3621
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
    • A61M5/1452—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons
    • A61M5/1456—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons with a replaceable reservoir comprising a piston rod to be moved into the reservoir, e.g. the piston rod is part of the removable reservoir
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
    • A61M5/1452—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons
    • A61M5/1458—Means for capture of the plunger flange
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31525—Dosing
    • A61M5/31526—Dosing by means of stepwise axial movements, e.g. ratchet mechanisms or detents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31576—Constructional features or modes of drive mechanisms for piston rods
    • A61M5/31578—Constructional features or modes of drive mechanisms for piston rods based on axial translation, i.e. components directly operatively associated and axially moved with plunger rod
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01B—MEASURING LENGTH, THICKNESS OR SIMILAR LINEAR DIMENSIONS; MEASURING ANGLES; MEASURING AREAS; MEASURING IRREGULARITIES OF SURFACES OR CONTOURS
    • G01B7/00—Measuring arrangements characterised by the use of electric or magnetic techniques
    • G01B7/003—Measuring arrangements characterised by the use of electric or magnetic techniques for measuring position, not involving coordinate determination
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H20/00—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
    • G16H20/10—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients
    • G16H20/17—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered via infusion or injection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
    • A61M2005/14506—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons mechanically driven, e.g. spring or clockwork
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M2005/2006—Having specific accessories
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31576—Constructional features or modes of drive mechanisms for piston rods
    • A61M2005/31588—Constructional features or modes of drive mechanisms for piston rods electrically driven
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/07—General characteristics of the apparatus having air pumping means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/33—Controlling, regulating or measuring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/33—Controlling, regulating or measuring
    • A61M2205/3317—Electromagnetic, inductive or dielectric measuring means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/33—Controlling, regulating or measuring
    • A61M2205/3327—Measuring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/50—General characteristics of the apparatus with microprocessors or computers
    • A61M2205/52—General characteristics of the apparatus with microprocessors or computers with memories providing a history of measured variating parameters of apparatus or patient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/70—General characteristics of the apparatus with testing or calibration facilities

Definitions

  • the present invention relates to a method for
  • the present invention relates to a digital storage medium according to claim 19, a
  • Syringe pumps are known from practice.
  • the associated pump control requires signals which are defined on
  • magnetic field sensors e.g. Hall sensors
  • optoelectronic sensors e.g.
  • Syringe pumps are used by the pump control to determine the current position of the slide and, by means of this, to correctly control the pump motor.
  • the syringe pump In order to ensure correct and precise control of the motor, the syringe pump must first have a
  • An object of the present invention is to provide a further, preferably automated or largely
  • a medical syringe pump that is configured and / or prepared to carry out such a method, and a blood treatment device are to be specified.
  • a suitable digital storage medium should be a
  • the object according to the invention is achieved by a method having the features of claim 1. It is also achieved by a medical syringe pump having the features of claim 9 and by a blood treatment device having the features of claim 17. Furthermore, the
  • Syringe parameters or to set up the syringe pump to be used with a further type of syringe, includes the provision of a medical syringe pump (here: syringe pump for short) which has a syringe holder with a syringe inserted therein.
  • the syringe has a syringe barrel and one therein between a first one
  • the syringe pump has a drive unit or a
  • Pump motor for example a syringe motor, in particular a stepper motor, and one by means of the drive unit in, in particular, on carriages which can be distinguished from one another or can be delimited from one another and moved by motor steps.
  • the carriage has a toggle for receiving one
  • This section can be a
  • a section of the carriage e.g. B. the toggle, is arranged relative to the syringe holder by means of the carriage so that it can move at most between a first end stop and a second end stop.
  • the slide is configured to be moved in motor steps (these can be micro-steps or partial steps). The slide is moved along the syringe inserted into the syringe pump.
  • the syringe pump comprises a counting device for counting or counting the number of motor steps by which the carriage is moved, for example similar to an odometer.
  • the counting device can preferably count up and down. She can go on
  • the syringe pump preferably comprises either one or more sensors or a sensor arrangement, which are each arranged along a displacement path of the piston of the syringe or a displacement path of the slide of the pump. They are optionally configured for this and / or
  • the syringe pump also includes a control device which is configured to use control instructions To cause the drive unit to move the slide.
  • control instructions can, for example, from
  • the syringe pump can accordingly calculate the amount of syringe pump.
  • the syringe pump optionally includes a correspondingly prepared or configured storage device.
  • the method according to the invention further comprises the following steps, which can be referred to herein as machine steps, at least if they are carried out automatically: a) Automatic and / or manual movement of the toggle by moving the slide of the syringe pump into a first position. This position corresponds to a first known nominal volume of the syringe or is assigned to such a nominal volume. A position value of the first position approached is then determined by means of the counting device and is the first
  • Position value determined b) Automatic and / or manual movement of the toggle by means of a movement of the slide of the syringe pump into a second position. This position corresponds to a second known nominal volume of the syringe or is assigned to such a nominal volume. Then a Position value of the approached, second position determined by means of the counting device and as the second
  • Amount between the first position value and the second position value in particular either as the number of motor steps by which the toggle was moved or moved to reach the second position starting from the first position, or by means of the position or positions determined with the aid of the position transmitter, determined in an absolute position measurement, e.g. B. by means of a linear potentiometer.
  • Nominal volume unit for example milliliters, or
  • the number of motor steps can be calculated, for example, by means of the difference or the amount between the first and the second position value based on a difference between the first nominal volume and the second nominal volume, or vice versa. Further determined and / or calculated parameters can also flow into this calculation.
  • Technical data of the syringe pump for example
  • the determination of a position value can be a simple reading of the count value, in particular when the toggle is moved from a reference point or began several times from the same reference point and there the respective starting value of the counting device z. B. was "0" or some other value.
  • a position transmitter all components that can be used to determine a position or a position value, in particular the counting device, the sensors, the sensors of the
  • Syringe pump in particular as disclosed herein, the optical sensors or magnetic field sensors mentioned herein, the permanent magnets, the Hall sensors, the slotted disc, the alternately magnetized index disc, etc., as well as any combination of two or any number of the aforementioned components.
  • the speed at which it is moved can be any speed at which it is moved.
  • Gag for example at a high speed
  • a microstep is a step size of the drive unit of the pump; the term can stand for a rotational measure or a linear measure.
  • the medical syringe pump according to the invention (for short:
  • Syringe pump includes a syringe holder. It is designed to receive a syringe, which a
  • the syringe pump further comprises a drive unit or a pump motor, for example a syringe motor, in particular a stepping motor.
  • the drive unit is provided to move a slide of the syringe pump into,
  • the slide here has a toggle for receiving a section of the plunger rod of the syringe or for connecting the toggle to it.
  • This section can be a pressure plate that is connected to the piston rod.
  • the toggle is arranged so as to be movable relative to the syringe holder by means of the slide at most between a first end stop and a second end stop.
  • the carriage is configured to be moved in motor steps (these can be micro-steps or partial steps) along the syringe inserted in the syringe pump.
  • the syringe pump comprises a counting device for counting or counting the number of motor steps by which the carriage is moved, for example similar to an odometer, which can preferably count up and down and which can further preferably be set to zero or another starting value.
  • the syringe pump optionally comprises one or more sensors or optionally a sensor arrangement.
  • the sensors or the sensor arrangement can along one
  • Displacement path of the plunger of the syringe or a travel path of the slide of the syringe pump can be arranged. you are optionally configured and / or arranged to work with the
  • the syringe pump also includes a control device, in particular as described above and / or which is configured to cause the drive unit to drive the slide by means of corresponding control instructions
  • control instructions can correspond to those already mentioned above, to which reference is made here in order to avoid repetitions.
  • the syringe pump optionally comprises a storage device.
  • control device of the medical syringe pump according to the invention is configured and / or prepared in order to use the medical syringe pump after the syringe has been inserted into a method, in particular the
  • a position value of the first position approached is then determined by means of the
  • Counting device as first position value; b) Automatic and / or manual movement of the toggle by means of a movement of the slide of the medical syringe pump into a second position. This position corresponds to a second known nominal volume of the
  • a position value of the approached, second position is then determined by means of the
  • Amount between the first position value and the second position value in particular either as the number of motor steps that the toggle was moved or moved to reach the second position starting from the first position, or by means of the position or positions determined with the aid of the position transmitter; and d) calculating a number of motor steps of the
  • the blood treatment device has a medical syringe pump according to the invention and / or is connected to such a pump in signal communication.
  • volatile storage medium in particular in the form of a machine-readable carrier, in particular in the form of a Floppy disk, CD, DVD, EPROM, FRAM (Ferroelectric RAM) or
  • SSD Solid State Drive
  • control signals that can be read out electronically or optically, can interact with a programmable computer system in such a way that the machine steps of the method according to the invention are initiated.
  • a computer program product has a volatile, volatile program code or a signal wave stored on a machine-readable carrier
  • a computer program product can for example be on a carrier
  • a computer e.g. client / server system, cloud computing system, etc.
  • a computer on which a computer program is loaded, runs, is stored, executed or developed e.g. client / server system, cloud computing system, etc.
  • machine readable medium as used herein
  • a computer program according to the invention has a program code to initiate the machine steps of the method according to the invention when the computer program runs on a computer. According to the invention, for example, a physical,
  • the computer program according to the invention means that all, some or some of the machine-carried out steps of the method according to the invention are initiated. This is especially true in conjunction with a
  • the nominal volume corresponds to the volume of fluid that is drawn up when the
  • the syringe is in the plunger up to the respective value of the nominal volume (e.g. 5 ml, 10 ml, etc.).
  • the syringe is usually indicated on the plunger by means of a scale, for example by imprinting, embossing or the like.
  • the nominal volume is used by the doctor if he wants a quantitative, precisely determinable volume of a fluid by means of a syringe
  • the first or the second position approached by means of the syringe pump corresponds to the first end position of the syringe, in particular the lower end position. At this lower end position, the syringe is completely emptied, which is why the nominal volume corresponding to this end position corresponds to zero milliliters (ml).
  • the method additionally comprises the automatic and / or manual movement of the toggle into the second end position of the syringe, which is done by moving the slide of the syringe pump. In these embodiments, the method further comprises determining a position value of the second end position by means of the
  • the toggle or an end section of the carriage reaches its maximum positions in each case when the carriage reaches the first end stop or the second end stop.
  • the detection that the first or the second end stop has been reached can take place by means of a perforated slotted disk or perforated disk, which is optionally part of the
  • the slotted disc can, for. B. via a coupling, from the spindle of the syringe pump, which, in conjunction with the pump motor, also drives the carriage in motor steps.
  • the slotted disc interrupts, when it rotates, intermittently a light barrier signal, e.g. B. according to a previously known pattern. If the slotted disc stops because the spindle that drives the slotted disc, in turn, when it reaches its mechanical end position
  • the control device of the syringe pump can use this
  • the first end stop of the syringe pump can be the lower of the two end stops. He can follow in one direction below (when using the syringe pump) represent the maximum position that can be reached by the slide.
  • an inside diameter of the syringe is additionally calculated. This can be done in the above Step d) or before or after it.
  • the knowledge of the inside diameter can be used to determine a step frequency, the delivery rate monitoring and / or a volume count.
  • the transmission and spindle-dependent parameters in particular the spindle pitch s [unit mm / 0 ], the step angle sw
  • the inside diameter d ⁇ can be calculated using the following formula:
  • V the nominal volume under consideration
  • the method comprises, e.g. B. as the first steps initiating the process, in addition, the insertion of a syringe standard in the syringe holder.
  • the normal syringe can be inserted into the syringe holder instead of the syringe or before or after inserting the syringe.
  • the toggle or slide is moved as far as that
  • This method can optionally take place in the direction of the first or the second end stop, e.g. B. in the direction of the lower end stop.
  • position value M the position value of the position thus reached within the syringe holder or trough is determined relative to the sensors of the syringe pump. This is referred to as position value M herein.
  • the spindle of the syringe pump which converts rotation into linear movement when the syringe is actuated, can alternatively be used together with the drive unit and the toggle
  • Syringe holder can vary from device to device due to tolerances in its attachment to the drive mechanism. Therefore, in some embodiments, it may be advisable to determine the position value M of the syringe cavity. He can indicate how the syringe cavity or receptacle in relation to the first or second, preferably calibrated beforehand
  • the method further comprises defining the position value of the first end position, alternatively defining the difference between the position value of the first end position and the position value of the position of the
  • Syringe intake as a first syringe parameter.
  • the method in these embodiments further comprises defining the position value of the second end position, alternatively the difference between the position value of the first end position and the position value of the second end position, as a second syringe parameter.
  • the method further comprises defining the difference between a position value of a specific nominal volume (for example the first or second
  • Embodiments transferring at least one value to at least one other medical device.
  • the transmitted value is a value from the group consisting of the first, the second, the third syringe parameter, the position value of the first end stop, the determined position value of the first end position, the determined position value of the second end position, the determined position value of the syringe holder, references to the Position values among each other, distances between
  • Transmission can for example be via the Internet, external service programs (e.g. PC service software), a network, coding (e.g. bar or QR code), in particular wireless, external data carriers (e.g. USB Stick) or by entering the parameters in the setup menu of the
  • the method further comprises the step of storing all or some data in the
  • Data can be determined and / or calculated data and / or values,
  • technical data of the syringe pump for example as set out above, can also be stored in the memory device.
  • the syringe is
  • Disposable syringe Disposable syringe.
  • the syringe pump position encoders or sensors are calibrated; H. the relative position of the movable toggle in relation to the sensors is known, optionally at any time.
  • the spindle movement and / or its standstill can be determined by means of at least one differently operating sensor, for example a magnetic field sensor such as a Hall sensor.
  • a magnetic field sensor such as a Hall sensor.
  • the above-mentioned slotted disc can thereby z. B. be replaced by an alternately magnetized index disc.
  • At least one resistance strip can be used
  • the travel speed of the carriage is variable; H. it can become slower, for example for the purpose of fine adjustment.
  • the deceleration can be used for fine adjustment or to determine the position M. It serves to minimize the error in determining the respective positions.
  • the control device can to
  • At least a determined number of motor steps and / or at least one is determined
  • Position value offset with a compensation value in order to be included in the calculation of the positions in a corrected or compensated manner.
  • An exemplary compensation can look like this:
  • Reaching the end stop is recognized, for example, on the basis of the absence ("time out") of the slotted disc signal to be expected for a sustained movement of the slide or on the basis of its change.
  • the time out obviously depends on the speed at which the slide is being calibrated is moved: If it is moved quickly, for example at a first speed, the
  • the slide for example lasts for at least 750 ms. If it is moved at a second speed, the slide can be assumed to have come to a standstill with a time-out that lasts for at least 1500 ms, for example. If it is moved slowly, for example at a third speed, it can be assumed that the slide is at a standstill with a time out that lasts for at least 3750 ms, for example.
  • Position values can be offset by such compensation values
  • the carriage has
  • Syringe pump on a permanent magnet This stands at an unchangeable distance to the toggle or to a
  • Section of the carriage such as the above. Section.
  • it is medical
  • Syringe pump designed as a heparin syringe pump.
  • Blood treatment device as peritoneal dialysis device, Hemodialysis device, hemofiltration device or designed as a hemodiafiltration device, in particular as a device for chronic renal replacement therapy or for continuous renal replacement therapy
  • the medical device in some embodiments, the medical
  • Syringe pump an input device for inputting
  • the medical device in some embodiments, the medical
  • Syringe pump a dispensing device for dispensing
  • Treatment data the determined syringe parameters and / or other data for a user, or is connected to such an output device, e.g. B. in wired or wireless way or in other ways.
  • the provision of data and / or values comprises a calibration process, the input of data by a user, the reading out of stored data and / or the like.
  • the first end position corresponds in particular to the information or the "syringe empty" state.
  • the second end position corresponds in particular to the information or the state “syringe fully or maximally drawn”.
  • method determined and / or calculated values of the delivery rate monitoring of the medical Syringe pump and / or volume counting and / or for
  • the syringe parameters are validated manually and / or automatically by a technician. For this purpose, the newly determined syringe parameters are checked and confirmed by the latter.
  • the first and second end positions do not correspond to the first and second end stops, respectively.
  • control device of the syringe pump is programmed to operate as intended, eg. B. during a treatment of the patient or dispensing of a liquid from the syringe, such as a drug, the operation of the syringe pump based on the
  • the syringe pump or its control device do not have any device for storing, determining and / or reading in the diameters, circumferences or radii of at least one syringe or its inner lumen. Saving, determining and / or reading in diameters, circumferences or radii of syringes and / or accessing such parameters takes place in some
  • inventive embodiments can have one, several or all of the advantages mentioned above and / or below.
  • inventive method enables
  • the parameters of the syringe which are important for knowledge can be ascertained without significant effort and further preferably also automatically by the syringe parameters
  • Syringe pump done by yourself Another advantage of this is that operating software does not have to be reprogrammed or updated, which always means effort.
  • Patients can be used at any time on site, for example by the user, the clinic or the service technician, or initiated.
  • Syringe parameters by the syringe pump on site, and z. Determine partly automatically or with little support from staff or technicians.
  • the method according to the invention advantageously enables a free selection of syringe types, for example for clinics or dialysis practices, since there are others individually on site
  • Syringe types can be learned and then used.
  • the relevant syringe type can then also be used there, without these other medical devices having to be newly set up specifically or at great expense or the syringe parameters or the end positions of this syringe type having to be determined again, even if syringe wells are different
  • Syringe pumps of the same device type were not installed exactly in the same way within the respective syringe pump.
  • the transmission can, for example, via the Internet
  • Fig. 1 shows a conventional syringe
  • Fig. 2 shows an embodiment of the
  • Syringe pump according to the invention in a schematically simplified plan view
  • Fig. La and Fig. Lb show, each from the side, a conventional, z. B. can be filled with heparin, syringe 1, which can be a disposable syringe and / or a pre-filled syringe.
  • Fig. La shows them in an empty state
  • Fig. Lb shows them in a completely filled state or which it assumes when it is completely filled.
  • the syringe 1 has a syringe barrel 2 and a
  • the syringe cylinder 2 has a head on it
  • the piston 5 is mostly made of an elastomeric material and is designed in the shape of a plug. It is located inside the syringe cylinder 2 and has a piston rod 6
  • Syringe cylinder 2 is axially displaceable.
  • the piston 5 ends with a mostly oval or round pressure plate 7 in plan view. It is shown from the side in FIGS. 1 a and 1 b.
  • the piston 5 is in a first end position B, in FIG. 1 b in a second end position C.
  • the piston 5 assumes the first end position B when the syringe contents have been completely emptied by moving the piston 5.
  • the piston 5 assumes the second end position C when the syringe 1 is filled to the maximum.
  • the displacement path of the piston 5 within the syringe 1 is therefore limited by the two end positions B and C. Its maximum displacement path to be complied with when the syringe 1 is used as intended, which is necessary to avoid a
  • Fig. 2 shows an embodiment of a disclosed one
  • Syringe pump 100 which has a syringe holder or
  • -trough 101 has. It also has a movable slide 103 with one that can be moved together with it
  • Slide 103 is stationary or is a stationary part thereof.
  • a drive unit 107 here for example a motor, moves, e.g. B. by means of a spindle 109, the carriage 103 in motor steps.
  • the direction in which the motor is moving e.g. B. by means of a spindle 109, the carriage 103 in motor steps.
  • Traverse path of the carriage 103 extends is means
  • the movement of the slide 103 comes to the left (with reference to FIG. 2), that is to say towards the Luer cone 3, at the latest when a first end stop A is reached, which is indicated by a dashed line.
  • the movement of the carriage 103 comes to the right (with reference to FIG. 2), that is to say towards the pressure plate 7, at the latest when a second end stop D is reached, which is also indicated by a dashed line.
  • the end stops A and D are to be understood as mechanical end stations of the slide 103: it is technically not possible to move the slide over these points A and D, even if no syringe 1 is inserted into the syringe pump 100.
  • the end stops A and D are each outside the first and second end positions B and C, respectively, described with reference to FIG.
  • a first sensor 111 and a second sensor 113 are optionally fixed on the syringe holder with e.g. B. connected to a housing of the syringe pump 100.
  • the slide 103 for its part, can have a permanent magnet 115, which can serve to determine in a known manner, in interaction with the first sensor 111 and / or the second sensor 113, if or when the slide 103 is the position of the first sensor 111 or the second
  • the first and second sensors 111 and 113 are optionally designed as Hall sensors. Evaluation devices required for determining or evaluating the signals received by the Hall sensors or other sensors are provided.
  • Sensor arrangement may be provided, optionally
  • Sensors for example composed of a Hall sensor and a light barrier, are also included in the present invention.
  • the invention also includes that z. B. move the two sensors 111 and 113, or just any one of them, stationary to the carriage 103 together with this when the carriage 103 is moved.
  • the syringe pump 100 also has a counting device 120, a control device 130, optionally one
  • Output device 150 or is herewith in
  • FIG. 2 shows the syringe pump 100 according to the invention with a syringe 1 inserted into it. This common representation serves to better explain the interaction of
  • the syringe pump 100 or syringe 1 For the method according to the invention, the syringe 1 must be inserted into the syringe pump 100 at least temporarily.
  • Fig. 3b and 3c show next to the two shown
  • Nominal volumes for example milliliters, allow the user z. B. to detect the fill level of the syringe and / or optionally dispensing of the contents
  • Syringe pump 100 is shown by way of example only in FIG. 3d.
  • FIG. 3 d illustrates that the counting device 120, the control device 130, the storage device 140 and the input / output device 150 can also be integrated into the syringe pump 100.
  • FIGS. 3a to 3d illustrate examples of determined syringe parameters SP1, SP2 and SP3.
  • the syringe parameter (SP1) corresponds to the first end position (B) (and also a nominal volume of zero ml), the second
  • Syringe parameter (SP2) corresponds to the second end position (C), and the third syringe parameter (SP3) is determined from the difference between z. B. the nominal volume (here: NI) and the first end position (B).
  • SP2 corresponds to the second end position
  • SP3 is determined from the difference between z. B. the nominal volume (here: NI) and the first end position (B).
  • Syringe 1 reached.
  • the determination of the syringe parameters SP1 to SP3 is shown here purely as an example.
  • the syringe parameters SP1, SP2 and / or SP3 can, optionally in addition to other parameters, such as a
  • Position value (M) of the syringe cavity or its reference or distance to one of the aforementioned values or a further value, such as the first end stop (A) or a first end position (B), in particular indicated as differences between any of the aforementioned variables, to other medical ones Devices are transmitted in order to save there a new calibration or setup of the device to the syringe type shown in Fig. 3a to 3d.
  • the difference between the first syringe parameter SP1 and the second syringe parameter SP2 can be used as a measure for a
  • position M Motor steps (measured from or based on the position of the lower end stop A) is used as position M.
  • the position M can indicate where - based on further
  • the value M can be corrected, for example by means of the compensation value mentioned herein.
  • the first syringe parameter SP1 can be determined here in any embodiments and detached from further features as the difference between M and B or as the difference between A and B.
  • the second syringe parameter SP2 can be determined herein in any embodiments and detached from further features as the difference between B and C or as the difference between A and C.
  • the third syringe parameter SP3 can be determined here in any embodiments and detached from further features as the difference between B and NI or N2.
  • Piston rod inside the syringe cylinder when the syringe is used as intended the maximum displacement is set in such a way that an undesired pulling out of the piston from the cylinder is avoided;

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Abstract

La présente invention concerne un procédé de détermination de paramètres de seringue. Comme première étape, il comprend la fourniture d'un pousse-seringue (100) médical comportant un logement à seringue (101) dans lequel est insérée une seringue (1), une unité d'entraînement (107) pour un chariot (103), un dispositif de comptage (120) pour compter des pas de moteur, au moins un capteur (111, 113), un dispositif de commande (130) et un dispositif de mémoire (140). Le procédé selon l'invention comprend en outre, comme étapes supplémentaires, le déplacement du chariot (103) successivement dans différentes positions (P1, P2) correspondant à des volumes nominaux connus (N1, N2) de la seringue (1). Dans une autre étape, la différence entre ces deux positions est déterminée et enfin, facultativement, un nombre de pas de moteur de l'unité d'entraînement du pousse-seringue par unité de volume nominal par rapport à la seringue (1) insérée est calculé.
EP20727962.1A 2019-05-21 2020-05-19 Procédé de détermination de paramètres de seringue au moyen d'un pousse-seringue, et dispositifs Pending EP3972671A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102019113460.9A DE102019113460A1 (de) 2019-05-21 2019-05-21 Verfahren zum Ermitteln von Spritzenparametern mittels einer Spritzenpumpe, und Vorrichtungen
PCT/EP2020/063958 WO2020234292A1 (fr) 2019-05-21 2020-05-19 Procédé de détermination de paramètres de seringue au moyen d'un pousse-seringue, et dispositifs

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EP3972671A1 true EP3972671A1 (fr) 2022-03-30

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US (1) US20220241495A1 (fr)
EP (1) EP3972671A1 (fr)
CN (1) CN113874058A (fr)
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WO (1) WO2020234292A1 (fr)

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CA3157480A1 (fr) * 2019-11-05 2021-05-14 Clayton Poppe Pompe a seringue
DE102021116994A1 (de) 2021-07-01 2023-01-05 B. Braun Melsungen Aktiengesellschaft Förderungsabsicherung bei einer Spritzpumpe
CN114563205B (zh) * 2022-04-28 2022-07-29 苏州恒瑞迦俐生生物医药科技有限公司 一种医用注射泵性能检测工装
CN116878856B (zh) * 2023-09-06 2023-11-28 长沙巨翊医疗科技有限公司 一种测试推注部件运动参数的装置及方法

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EP0434672B1 (fr) * 1987-06-19 1994-12-14 The University Of Melbourne Pompe d'injection
US5236416A (en) * 1991-05-23 1993-08-17 Ivac Corporation Syringe plunger position detection and alarm generation
US5651775A (en) * 1995-07-12 1997-07-29 Walker; Richard Bradley Medication delivery and monitoring system and methods
GB0228767D0 (en) * 2002-12-10 2003-01-15 Zi Medical Plc A syringe driver assembly
DE102007044413A1 (de) * 2007-09-18 2009-03-19 Fresenius Medical Care Deutschland Gmbh Verfahren zur Überprüfung und/oder Überwachung der korrekten Funktion einer Zugabevorrichtung
GB2526804B (en) * 2014-06-02 2019-10-16 The Queen Elizabeth Hospital Kings Lynn Nhs Found Trust An apparatus for the control of regional anaesthesia
DE102018108203A1 (de) 2018-04-06 2019-10-10 Fresenius Medical Care Deutschland Gmbh Verfahren zum Kalibrieren einer Spritzenpumpe, Spritzenpumpe und Vorrichtungen

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