EP3893676A4 - Methods to reduce harmful effects of smoking cigarettes, cigars and tobacco, and of exposure to smoke from cigarettes, cigars and tobacco by using kynurenic acid in nanoparticle carrier systems - Google Patents

Methods to reduce harmful effects of smoking cigarettes, cigars and tobacco, and of exposure to smoke from cigarettes, cigars and tobacco by using kynurenic acid in nanoparticle carrier systems Download PDF

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Publication number
EP3893676A4
EP3893676A4 EP17813671.9A EP17813671A EP3893676A4 EP 3893676 A4 EP3893676 A4 EP 3893676A4 EP 17813671 A EP17813671 A EP 17813671A EP 3893676 A4 EP3893676 A4 EP 3893676A4
Authority
EP
European Patent Office
Prior art keywords
cigars
tobacco
cigarettes
smoke
exposure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP17813671.9A
Other languages
German (de)
French (fr)
Other versions
EP3893676A1 (en
Inventor
Monika TURSKA
Gabrielle TURSKI
Christopher Turski
Michal Turski
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of EP3893676A1 publication Critical patent/EP3893676A1/en
Publication of EP3893676A4 publication Critical patent/EP3893676A4/en
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/18—Treatment of tobacco products or tobacco substitutes
    • A24B15/28—Treatment of tobacco products or tobacco substitutes by chemical substances
    • A24B15/30—Treatment of tobacco products or tobacco substitutes by chemical substances by organic substances
    • A24B15/36—Treatment of tobacco products or tobacco substitutes by chemical substances by organic substances containing a heterocyclic ring
    • A24B15/38—Treatment of tobacco products or tobacco substitutes by chemical substances by organic substances containing a heterocyclic ring having only nitrogen as hetero atom
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24D—CIGARS; CIGARETTES; TOBACCO SMOKE FILTERS; MOUTHPIECES FOR CIGARS OR CIGARETTES; MANUFACTURE OF TOBACCO SMOKE FILTERS OR MOUTHPIECES
    • A24D3/00—Tobacco smoke filters, e.g. filter-tips, filtering inserts; Filters specially adapted for simulated smoking devices; Mouthpieces for cigars or cigarettes
    • A24D3/02—Manufacture of tobacco smoke filters
    • A24D3/0204—Preliminary operations before the filter rod forming process, e.g. crimping, blooming
    • A24D3/0212—Applying additives to filter materials
    • A24D3/0216—Applying additives to filter materials the additive being in the form of capsules, beads or the like
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24D—CIGARS; CIGARETTES; TOBACCO SMOKE FILTERS; MOUTHPIECES FOR CIGARS OR CIGARETTES; MANUFACTURE OF TOBACCO SMOKE FILTERS OR MOUTHPIECES
    • A24D3/00—Tobacco smoke filters, e.g. filter-tips, filtering inserts; Filters specially adapted for simulated smoking devices; Mouthpieces for cigars or cigarettes
    • A24D3/04—Tobacco smoke filters characterised by their shape or structure
    • A24D3/048—Tobacco smoke filters characterised by their shape or structure containing additives
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24D—CIGARS; CIGARETTES; TOBACCO SMOKE FILTERS; MOUTHPIECES FOR CIGARS OR CIGARETTES; MANUFACTURE OF TOBACCO SMOKE FILTERS OR MOUTHPIECES
    • A24D3/00—Tobacco smoke filters, e.g. filter-tips, filtering inserts; Filters specially adapted for simulated smoking devices; Mouthpieces for cigars or cigarettes
    • A24D3/06—Use of materials for tobacco smoke filters
    • A24D3/14—Use of materials for tobacco smoke filters of organic materials as additive
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
EP17813671.9A 2016-06-15 2017-06-14 Methods to reduce harmful effects of smoking cigarettes, cigars and tobacco, and of exposure to smoke from cigarettes, cigars and tobacco by using kynurenic acid in nanoparticle carrier systems Pending EP3893676A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PL417590A PL235970B1 (en) 2016-06-15 2016-06-15 Methods for reducing harmful effects of smoking cigarettes, cigars, tobacco and exposure to smoke, with burning cigarettes, cigars and tobacco by kynurenic acid in nanoparticle carrier systems
PCT/PL2017/000064 WO2017217877A1 (en) 2016-06-15 2017-06-14 Methods to reduce harmful effects of smoking cigarettes, cigars and tobacco, and of exposure to smoke from cigarettes, cigars and tobacco by using kynurenic acid in nanoparticle carrier systems

Publications (2)

Publication Number Publication Date
EP3893676A1 EP3893676A1 (en) 2021-10-20
EP3893676A4 true EP3893676A4 (en) 2022-10-12

Family

ID=60655754

Family Applications (1)

Application Number Title Priority Date Filing Date
EP17813671.9A Pending EP3893676A4 (en) 2016-06-15 2017-06-14 Methods to reduce harmful effects of smoking cigarettes, cigars and tobacco, and of exposure to smoke from cigarettes, cigars and tobacco by using kynurenic acid in nanoparticle carrier systems

Country Status (5)

Country Link
EP (1) EP3893676A4 (en)
PL (1) PL235970B1 (en)
RU (1) RU2699595C1 (en)
WO (1) WO2017217877A1 (en)
ZA (1) ZA201905960B (en)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3766261A (en) * 1970-08-21 1973-10-16 Us Agriculture Process of producing kynurenine
US6470894B2 (en) * 1997-09-19 2002-10-29 Thione International, Inc. Glutathione, green tea, grape seed extract to neutralize tobacco free radicals
EP1369114A1 (en) * 2002-06-07 2003-12-10 Peter Priv. Doz. Dr. Terness Use of tryptophan metabolites as pharmaceutical agents
PL383112A1 (en) * 2007-08-09 2009-02-16 Forty-Four Pharmaceuticals Spółka Z Ograniczoną Odpowiedzialnością Methods of increasing the content of kynurenic acid in lungs

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3766261A (en) * 1970-08-21 1973-10-16 Us Agriculture Process of producing kynurenine
US6470894B2 (en) * 1997-09-19 2002-10-29 Thione International, Inc. Glutathione, green tea, grape seed extract to neutralize tobacco free radicals
EP1369114A1 (en) * 2002-06-07 2003-12-10 Peter Priv. Doz. Dr. Terness Use of tryptophan metabolites as pharmaceutical agents
PL383112A1 (en) * 2007-08-09 2009-02-16 Forty-Four Pharmaceuticals Spółka Z Ograniczoną Odpowiedzialnością Methods of increasing the content of kynurenic acid in lungs

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
See also references of WO2017217877A1 *
VARGA N ET AL: "Targeting of the kynurenic acid across the blood-brain barrier by core-shell nanoparticles", EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, ELSEVIER AMSTERDAM, NL, vol. 86, 23 February 2016 (2016-02-23), pages 67 - 74, XP029492456, ISSN: 0928-0987, DOI: 10.1016/J.EJPS.2016.02.012 *

Also Published As

Publication number Publication date
PL235970B1 (en) 2020-11-16
WO2017217877A1 (en) 2017-12-21
RU2699595C1 (en) 2019-09-06
ZA201905960B (en) 2021-07-28
EP3893676A1 (en) 2021-10-20
PL417590A1 (en) 2017-12-18

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