EP3801852A1

EP3801852A1 - Metering device for solid moulded bodies for producing a solution

Info

Publication number: EP3801852A1
Application number: EP19728052.2A
Authority: EP
Inventors: Gerome FISCHER; Tobias Stöckerl
Original assignee: Fresenius Medical Care Deutschland GmbH
Current assignee: Fresenius Medical Care Deutschland GmbH
Priority date: 2018-06-05
Filing date: 2019-06-03
Publication date: 2021-04-14
Also published as: WO2019233924A1; CN112292199A; US20210331123A1; DE102018004419A1; CA3098287A1

Abstract

The invention relates to a device for producing a medical solution by adding substances present in solid moulded bodies into a solvent, comprising a mixing container, which can be filled with a solvent via an inlet, and from which the solution produced by the device can be supplied via an outlet, and which also has a feed opening via which the solid moulded bodies can be introduced into the mixing container. The device also comprises a metering device for controllable selective feeding of solid moulded bodies, or parts thereof, having different constituents and/or different concentrations of constituents from one or more storage containers which are held in one or more corresponding receptacles of the device and in which the solid moulded bodies can be removably held. The device may also have a coding and identification device for identifying and evaluating a mechanically evaluatable coding which is associated with a storage container and contains information concerning which constituents are contained in the solid moulded bodies stored in the respective storage container.

Description

Dosing device for solid shaped bodies for the preparation of a solution Description

The present invention relates to a metering device for solid shaped articles or parts thereof for the preparation of a solution, preferably a medical solution.

State of the art

Solutions of solids present in a liquid, for example water, are used in many places and for a wide variety of purposes. For example, to kill germs in swimming pools, treat the water with chlorine. The chlorine can be used as a solid shaped body or granules in an inflow of the

Swimming pool are introduced, where the solid-shaped body dissolves over time and continuously releases chlorine in the water.

The dosage by adding one or more of the solid-form body depends on the water volume of the pool and the speed at which dissolve or decay the solid or. In the above

described application and compliance with the dosage is required only in a relatively wide tolerance range, so that, just because of the usually large volume of water in swimming pools, a slightly too large or too small number of solids in a mixing process usually has no problematic effects. Frequently, only a decreasing over time the concentration of the dissolvable solid-form body added substance is compensated, so that at intervals individual solid-form body of the substance are added to the dissolution. The addition can be done manually.

The dissolvable solid form bodies for preparing solutions by dispensing substances into a solvent, for example water, may be in tablet form. In an automatic device, tablets are individually removed from a storage container by means of an ejector and conveyed into a mixing container in which the tablets dissolve, so that after a certain time a homogeneous solution is obtained. It may be necessary to change the composition of a solution during use. If only a change in the concentration of the solutes in otherwise identical proportions of existing components is required, this can be done with the known methods and

Devices by simply adding appropriate additional tablets in the mixing container done. If the solution is to be consumed and prepared continuously or quasi-continuously, i. a portion of the solution with equal or variable volume flows is removed from a mixing vessel and the missing volume is replaced by added solvent is for the

Adjustment of the concentration of the substances in the finished solution requires the finest possible control of the addition of individual substances.

Certain applications, e.g. in medicine and here, for example, in dialysis, require at relatively small volumes of a solution to be prepared a precise adjustment of the concentration of different substances and u.U. an individual change in the concentration of individual substances during one

Treatment. Again, the finest possible control of the addition of individual substances is required.

Dialysis is a procedure for purifying the blood of patients with acute or chronic renal insufficiency. Basically, a distinction is made here between methods with an extracorporeal blood circulation, such as hemodialysis, hemofiltration or hemodiafiltration (hereinafter referred to as hemodialysis

summarized) and peritoneal dialysis, no extracorporeal

Having blood circulation.

The blood is passed in hemodialysis in an extracorporeal circuit through the blood chamber of a dialyzer, which is separated by a semipermeable membrane of a dialysis fluid chamber. The dialysis fluid chamber is contained by one of the blood electrolytes in a certain concentration

Flows through dialysis fluid. The substance concentration of the dialysis fluid corresponds to the concentration of the blood of a healthy person. During treatment, the patient's blood and the dialyzing fluid on both sides of the membrane generally countercurrently flow at a predetermined rate past. The urinary substances diffuse through the membrane from the blood chamber into the chamber for dialysis fluid, while at the same time in the blood and in the dialysis fluid existing electrolytes from the chamber higher

Diffuse concentration to the chamber of lower concentration.

If a pressure gradient from the blood side to the dialysate side is established on the dialysis membrane, for example by a pump which removes dialysate from the dialysate circuit downstream of the dialysis filter on the dialysate side, water passes from the patient's blood via the dialysis membrane into the dialysate circuit. This process of ultrafiltration leads to a desired drainage of the

Patient's blood.

In haemofiltration, blood is applied to the patient's blood by applying a

Transmembrane pressure in the dialyzer ultrafiltrate withdrawn without

Dialysis fluid is passed on the patient's blood opposite side of the membrane of the dialyzer. In addition, a sterile and pyrogen-free substituate solution can be added to the patient's blood. Depending on whether this Substituatslösung is added upstream of the dialyzer or downstream, it is called pre- or post-dilution. The mass transfer takes place at the

Haemofiltration convective.

Hemodiafiltration combines the methods of hemodialysis and the

Hemofiltration. There is both a diffusive mass transfer between the patient's blood and dialysis fluid via the semipermeable membrane of a dialyzer, as well as a filtration of plasma water by a pressure gradient at the membrane of the dialyzer.

Plasmapheresis is a procedure whereby blood plasma is corpuscular

Blood components (cells) is separated. The separated blood plasma is purified or replaced with a substitution solution and returned to the patient.

In peritoneal dialysis, the abdominal cavity of a patient is filled via a guided through the abdominal wall catheter with a dialysis fluid, the

Concentration difference compared to the body's own fluids. over The membrane acting peritoneum (peritoneum), the toxins present in the body pass into the abdominal cavity. After a few hours, it will be in the

Abdominal cavity of the patient located now exchanged dialysis fluid exchanged. Osmotic processes allow water from the patient's blood to pass through the peritoneum into the dialysis fluid and drain the patient.

The procedures for dialysis are usually with the help of automatic

Dialysis machines, such as those sold by the applicant under the name 5008 or sleep.safe carried out.

The dialysis fluid is provided either ready-mixed, for example. In bags, or by mixing water whose purity meets medical requirements, with certain ingredients. The dosage of the ingredients can be difficult, especially if no saturated solution is required.

Pumps of different design are used to convey fluids in medical treatment devices. In devices with extracorporeal blood circulation, such as hemodialysis devices, peristaltic tube roller pumps are often used. This

Hose roller pumps are frequently used in medical technology because they allow a contactless transport of a liquid. In addition, they theoretically provide a flow proportional to the speed in a wide range, regardless of the flow resistance upstream and downstream of the pump. In a blood pump in extracorporeal treatment method refers to the feeding (suction) side as an arterial side with a self-adjusting suppression of typically about -100 to -300 mm mercury column to external pressure, and the laxative side as a venous side with a self-adjusting overpressure the external pressure. Other pumps used in dialysis are impeller pumps, diaphragm pumps, or generally positive displacement pumps, e.g. Piston pumps, the shape of the

Displacer may vary.

A problem of the known methods and devices is that for a given volume of the mixing container or a predetermined target volume the solution to be prepared, the solution can be produced only in dependent on the number of dissolved tablets concentrations. This problem can be reduced with the known means only by a suitable selection of the respective volume to be produced and the respective amount of contained in a tablet, possibly also different substances. In this case, the size of the tablet, ie diameter and thickness can be adjusted only within certain limits, if the dosing to be used for the production of different solutions using tablets with different ingredients or amounts.

The preparation of a solution with varying concentrations of different substances is not possible at all by adding tablets with a fixed distribution of the ingredients.

Summary

It is therefore desirable to provide a device and a method which allow a more flexible control of the concentration of contents of a solution obtained by dissolution of solid-form bodies in a solvent even with changing target concentrations of different ingredients. It is further desirable to provide a medical device or system that implements such a method or includes such a device.

The term "solids-shaped body" is hereinafter synonymous with the term "tablets" for molded, crystalline or otherwise, in one

Solvent-soluble, solid-state substances or mixtures of tablets used.

A device according to the invention for producing a medical solution by adding solid-form bodies into a solvent comprises a mixing container which can be filled with a solvent via an inlet, and from which the solution can be supplied for use via a drain. The mixing container, which has a first volume, also has an addition port through which the solid-form body can be introduced into the mixing container. Feed and addition ports may be separate or as a single port. The apparatus further comprises a metering device for the controllable selective addition of solid-form bodies, or parts thereof, of one or more, stored in one or more corresponding receptacles of the device

Storage containers, in which the solid form body are removably stored, in the mixing vessel.

Controllable selectively may mean in this context that individual solids molded body can be selectively introduced from one or more of a plurality of storage containers in the mixing container. Controllable selectively in this context can also mean that when solid-form body with

different ingredients or different concentrations of

Ingredients are stored in a known order in a reservoir, and individual of the solid-form body, which are not immediately available next to a discharge opening of a reservoir, can be introduced into the mixing vessel.

The stored in a reservoir solids form body may contain the same or different ingredients. The stored in a reservoir solid-shaped body can also contain one or more ingredients in

contain different concentrations and / or mixing ratios. The tablets may be round or polygonal and have at least along a portion of the peripheral edge to a certain, predetermined thickness. They can therefore have the same thickness everywhere, or only along the circumference of the tablet, or only along parts of the circumference. In order to be able to provide different amounts of ingredients for a given thickness of the tablets, the tablets may, for example, have a reduced thickness or even a hole in the middle. If the tablets are breaking points

For example, by reducing the thickness in certain areas, notches or the like, the remaining areas may have the same thickness. In any case, the areas of the largest thickness of the tablet are designed so that regardless of the displacement of two superimposed tablets against each other these can not get caught when moving. Each two superimposed tablets always has two or more Pads or surfaces that do not penetrate a plane lying between the tablets.

The apparatus may further comprise a code recognition device for recognizing and evaluating a reservoir connected to a reservoir

evaluable coding. The coding contains information about which ingredients are contained in the stored in the respective reservoir solids moldings. The coding may also contain information about the order in which the stored in the respective storage container solid-shaped bodies are stored, if solid-form body are stored with different ingredients, amounts, concentrations and / or mixing ratios of ingredients in the reservoir.

Each of the receptacles for reservoir of the device may comprise an actuator which is releasably coupled to an ejector unit of a receptacle to be received by the receptacle. The detachable connection is designed such that it allows a force transmission of the actuator to a movable closure piece of the ejector unit at least in one direction.

It is also possible to arrange several receptacles for reservoir on a movable support. The carrier can, for example, be linear along a trajectory

slidably or rotatably mounted on a carousel. At this

Embodiment, at least one actuator is necessary, which is operatively coupled with a brought by the carrier in a specific position reservoir or its ejector unit and is controllable to remove from this one or more solid moldings. For supplying different solid-form body each a corresponding reservoir is placed in the specific position, so that the actuator can be coupled to the corresponding ejector unit to remove one or more solid-form body from this reservoir. Depending on the design, several actuators can be provided here, which allow a simultaneous removal of solid-form bodies.

The closure piece may be a first recess or first punched out

having a single tablet after removal from the Reservoir for promotion in the mixing container or to another location receives. The first cut-out or first punch-out may correspond to the shape and / or size of the tablet so that it can be received in it with little play. The first recess or first punch-out may also be configured to limit or prevent rotation of the tablet about a floating axis during the conveying operation.

A power transmission in one direction may include, for example, pushing or pushing the ejector unit, wherein a return of the ejector unit and the actuator in a starting position by another, in

opposite direction acting actuator or by a corresponding spring force.

A power transmission in two directions can be achieved, for example, by a non-positively or positively coupled to the ejector actuator, which can move the ejector in two opposite directions. A positive coupling between ejector and actuator can by accordingly

Interlocking coupling elements are achieved, for example. A

Dovetail. A frictional coupling can be achieved, for example, by an electromagnet acting on a corresponding metallic counterpart.

The ejector unit can be identical to the closure piece or comprise, in addition to the closure piece, further components, for example parts for supporting or guiding the closure piece.

The code recognition device for recognizing and evaluating a machine-evaluable coding connected to a storage container may comprise means for inserting a storage container into a receptacle

signal. These means of detection may e.g. one or more

electrical, magnetic or optical contacts comprising a

provide appropriate signal and / or activate a power supply. The evaluable coding may include a shape of the receptacle, which receives only reservoir with a corresponding shape of the male part of the recording. In storage containers with an identical shape in this case are preferably always solid-form body with identical ingredients or identical sequence of different ingredients stored. The mating shapes of receptacle and counterpart on the reservoir and the recognition of the insertion of such a reservoir so cause an implicit recognition of the content.

The coding recognition device for recognizing and evaluating a machine-evaluable coding connected to a storage container may alternatively or additionally comprise a reading device for reading out an optical, magnetic or electrical coding. Optical readers include, for example, devices for detecting and recognizing QR codes, bar codes, or for performing an optical character recognition (OCR). It can be provided for each recording a corresponding reading device, which is directed to a known position of the coding on the reservoir. It is also possible to arrange a single reading device to be movable

sequentially or as needed to recognize a coding of a reservoir, or to detect a not attached to a known position of the reservoir coding. It is also possible, only one optics of

Reading device instead of the entire reading device on the coding

align different reservoir. The optics may include mirrors, lenses, optical fibers and the like.

Electrical reading devices include, for example, one or more electrical contacts whose states (open / closed) represent a code, near field communication (NFC), radio frequency identification (RFID),

Devices for measuring resistances, impedances or resonances, or the like. The electrical contacts can also be in operative connection with conductive imprints or stickers on the reservoir, wherein electrically conductive paths between individual pairs of contacts can be left open or closed by means of the imprints or stickers and thus form a binary coding. It is also possible by means of the imprints or stickers Set impedances between pairs of contacts that represent a unique code.

In the case of the electric or optical reading device, the receptacles of the reservoir and the corresponding counterparts of the reservoir can have identical shapes. If storage containers in which solids having different contents are stored can be stored in any receptacle, the device recognizes by means of the coding which ejector is to be controlled in order to add certain ingredients to the solution.

The apparatus may also include one or more units for ensuring the conveyance of solids to an opening of the one or more reservoirs coupled to the apparatus. These units may be adapted to transfer mechanical shocks or vibrations to the reservoir, for example by means of a plunger or percussion mechanism, or by abutment of the stopper, the ejector unit or the actuator to a stop. It is also conceivable that the closure piece and a guide, in which the closure piece is guided, are profiled, so that upon movement of the closure piece in the guide mechanical shocks or vibrations are transmitted to the reservoir. The profiling may include, for example, toothed or undulating surfaces.

The mixing container may be a disposable mixing container or a reusable mixing container. The device may have a corresponding holder for removably receiving the mixing container. In the case of a disposable mixing container this can be a plastic bag with a specific

Capacity, which is stored in a holder. The holder may be configured to define the plastic bag to the one or more

Position dosing devices.

The holder for the mixing container may comprise a guide device, which with the insertion of the disposable mixing container into the device, the inlet, the outlet and / or the addition of the opening of the disposable mixing container with

corresponding connections or openings of the device connects automatically or align them to each other so that their function is guaranteed. In the latter case, there may be occurrences that the mixing container or the inlet, outlet and / or addition opening are not in direct contact with the device or the corresponding terminals of the device.

In one or more embodiments of the device, this also has a Fleizeinrichtung for heating the mixing container, means for generating a flow in the mixing container, and / or means for introducing a gas into the mixing container. Among other things, each of the abovementioned devices can also serve or contribute directly or indirectly to improved mixing of the solution or of the substances introduced into the solution.

In one or more embodiments, the device has a

Deflection device, which exerts a force which acts in a second direction at least on a part of a solid shaped body which is conveyed from the reservoir in a first direction after removal from the reservoir. The second direction points out of a first plane in which the first direction lies. The deflector comes in contact with the solid-shaped body and is effective when the closure piece has traveled a certain first distance in the first direction.

The deflection device may comprise a deflection lever which passes through the

Actuator is actuated directly or indirectly, or operated with a separate actuator deflection ram, which is actuated when the

Closure piece has covered the particular first route. In the latter case, a device for determining the distance or a signal generator may be provided, which provides a signal when the closure piece has traveled the specific first distance.

The deflection device may alternatively comprise a fixed part of the device lying in the conveying path of the closure piece, which engages in a second recess of the closure piece. The second recess extends at least from a front side of the closure piece lying in the first direction up to the first recess or first punch, in which a solid molded body can be received after removal from the reservoir. The fixed part is arranged to the first plane that is exerted on the solid molded body in a promotion beyond the certain first distance beyond a force acting in the second direction force.

The deflector can solve the entire solid-form body from the first recess or first punched so that it can get into the mixing container.

However, the deflector can also solve only first parts of a solid-form body from the first recess or first punched so that it can get into the mixing container. Second parts of the solid-form body remain in the first recess or first punched. Flierzu the metering device or the closure piece may be designed so that remaining second parts are not or only slightly movable in the second and / or an opposite direction. In other words, second parts of the tablet are in the

Recess or punching of the closure piece more or less fixed, so that the first parts can be canceled.

The solid-form body can be broken by the deflector in two or more parts. A defined division of the solid-form body can be achieved by appropriate breaking points. This partial supply of solid-form bodies allows a finer dosage of substances in the solution. In addition, the breakage of the solid moldings also increases their surface area so that a faster dissolution in the solvent can be achieved.

In order to achieve a targeted sharing of solid-form bodies along predetermined breaking points, it may be necessary to ensure a certain orientation of the solids molded body with respect to the first direction during movement to the deflector. For this purpose, the solid-shaped body may have a shape which cooperates with corresponding means of the closure piece and / or the storage container or storage volume. These means may comprise a form of the tablet and the reservoir or storage volume, at least in the region of an opening through which the solid form body are removed from the reservoir or storage volume, as well as with the recess or punching of the closure piece so that a predetermined orientation of the solid-form body with respect to the first

Direction is ensured. This can be achieved for example by a non-circular shape of the solid-form body and a corresponding shape of the reservoir or storage volume and the punched or recess of the closure piece. The means may also include one or more guide ribs in the

Supply volume or the reservoir and the recess or punching of the closure piece include, which engage in corresponding recesses of the solid molded body. If the means are provided both on or in the storage volume or storage container and on or in the closure piece, these are expediently removed in a position of ejector unit or closure piece and storage container or storage volume in which a solid form body is removed from the storage container or storage volume. aligned with each other.

In one or more embodiments of the device, the

Dosing a selection on, by means of which solid form body or parts thereof can be promoted either in the mixing container or in another container. The further container can, for example, to be discarded solids molded body or parts thereof.

This selection device may comprise a reversible switch located in the conveying path, or an ejector which removes a solid mold body or a part thereof after removal from the storage container and before being fed into the mixing container from the conveying path leading into the mixing container. For example, the ejector may exert a mechanical or pneumatic impulse on the solid form to be removed from the conveying path, or parts thereof, thereby removing it from the supply into the mixing container.

For example, it is thereby possible first to convey first parts of a solid shaped article into the mixing container, and then to convey second parts of the solid shaped article into the further container. The movement of the stopper can be stopped briefly after breaking off the first parts Switched over switch and the ejector activated, and then continue the movement of the closure piece and the ejector act.

The switch may alternatively be replaced by an extended conveying path of the closure piece, via which a solid form body or parts thereof can be conveyed into the further container. The extended conveying path may comprise, in addition to the movement of the closure piece in the first direction, a movement of the closure piece in a third direction. The third direction may be the first direction

be opposite, or transverse to it. The first and third directions may be substantially in one plane. In this alternative, a part of a tablet can be introduced into the mixing container, for example by the

Closure piece moves the tablet in the first direction against the deflector, which separates the part from the tablet. After that it will be

Shutter moves in the third direction and the remaining part of the tablet promoted in the other container. It is also possible in this alternative to promote whole tablets equal to the other container, for example, when tablets are stored with different ingredients or concentrations of ingredients in a known order in the reservoir, and some of them should not be introduced into the mixing container.

In one or more embodiments of the device is a

Detection device provided, which is the provision of a

Solid form body signaled from the reservoir into the metering device. The detection device may be the inclusion of a solid-form body in the ejector unit or the closure piece by optical means, for example. One or more light barriers, or by electrical means, for example. One or more indirectly or directly by the provided solid-form body actuated contacts include. The detection device may also comprise an arrangement for detecting a weight, a change in weight or a triggered by a solid-form body mechanical pulse. The

Recognition device can be arranged in the ejector unit or in the closure piece, or the weight or a change in weight of the

Capture reservoir. In the latter case, an absolute detection of the Fill level of the reservoir possible. A weight or pulse detection is possible eg with a load cell.

In one or more embodiments of the device, two or more mixing containers are provided, which are alternately positioned to the metering device, that in each case a solution can be produced. Thus, either two different solutions can be made almost simultaneously, or a solution is always made while consuming a previously prepared solution. Thereby, a quasi-continuous operation is possible, wherein a change in the solution composition either when switching to the other mixing container is effective, or the solution composition is changed during the consumption of the solution by appropriate addition of solid-shaped bodies.

A reservoir of any of the above-described devices or

Variants thereof include a storage volume, the solid-shaped body receives in a defined arrangement. A defined arrangement in the context of the invention means that the solid form body are not stored in a loose, disorderly manner in the storage volume, but are arranged in a defined, fixed manner to each other, for example, stacked or stacked. An arrangement next to each other or the like is possible. A defined arrangement also includes a specific sequence of different solid-form body with respect to a removal opening of the reservoir or storage volume.

The reservoir also has an opening through which the stored in the reservoir volume solid form body can be removed. The opening may, for example, be located at an underside of the storage volume when the storage container is placed in a receptacle of the device. The filling of the storage volume can be carried out through the removal opening, but it can also be provided a separate filling opening. Likewise, a vent opening may be provided which fluidly connects the reservoir volume with an environment. The ventilation opening may be provided with a filter, which the Penetration of foreign bodies, fluid molecules of a certain size and the like prevented.

The reservoir also has a disposed at the opening

Ejector on which is releasably coupled to an actuator of the device. The ejector unit may comprise a closure piece movably guided along a predetermined trajectory which releases the opening of the stock volume in a first position and blocks it in one or more second positions not corresponding to the first position along the trajectory. By released in the first position opening can be a solid-shaped body of the

Reservoir be removed and enter a conveyor track so that it can be transported or rejected by the ejector unit in the mixing container. In the second positions, no solid-shaped body of the

Outlet volume, the opening is blocked. A blocked opening need not be completely closed, although this may have advantages in terms of protecting the not yet removed solid form body from damage or contamination. It is sufficient if no solids molding can pass through the opening. The trajectory and / or the conveyor track can run in one plane, for example in two opposite directions along a

Straight line or a general arc segment. However, the trajectory and / or the conveyor track can also run along an arbitrarily shaped surface, for example along an ellipsoidal surface. The ejector unit, in one embodiment, for example, the closure piece, can receive a solids molded body removed from the storage volume and convey the trajectory to the mixing container of the apparatus or to another container, the solid moldings or parts not used for the Fierstellung of the solution receives from it.

The ejector unit may be permanently or detachably connected to the storage volume. At least the closure piece or the part of the ejector unit, which

Solid form promotes body, while expediently has a dimensioning, which is adapted to the dimensions and shape of the solid form body. However, it is also possible to design a Auswerfereinheit bodies for different shapes and sizes of solid-form. Here is the suitability for the Blocking or releasing the opening in the first or in other positions to take into account. Possibly. is provided a corresponding separate part or a separate mechanism for this function, the bodies or an uncontrolled slipping solids mold prevents from the storage volume.

The reservoir further comprises a machine recognizable, readable and / or evaluable coding, which contains information about which ingredients are contained in the stored in the reservoir solid-shaped body. The information may, for example, indicate which mixing ratios of different ingredients are present in the solid-form bodies, or in which order solid-form bodies are stored with different ingredients or mixtures of ingredients within a storage volume with respect to the removal opening.

A closure piece of the ejector unit of the storage container may comprise a component which has a substantially planar surface at least on a side facing the opening. The component may have transversely to the first direction has a width which extends beyond the width of a body to be conveyed by the closure piece of solid form. In the component can be a

Recess or punching be provided, which receives a solid-form body for promotion. The component may be solid except for the recess or have a plurality of interconnected webs forming a space for receiving a solid-shaped body and at least one area for blocking the opening of the reservoir. The component may have a thickness at least in the area for blocking the opening of the reservoir, which corresponds to that of the solid-shaped body to be conveyed. At least the upper side of the component lies in this area in a plane with the highest elevation of a solid shaped body accommodated in the component facing the opening, even if the thickness of the component is lower in this area.

The recess or punching may be in shape and / or size

Be adapted to be absorbed solid-form body. The recess or punching can completely break through the closure piece, or have an at least partially circumferential edge. In the first case is on the Opening the storage volume opposite side of the recess provided a surface on which the solid-form body can be moved along the trajectory. In the second case, the solid-form body can rest on the edge, and there is provided a mechanism that dissolves the solid-form body from the recess or the punch, so that the solid molded body or parts thereof can get into the mixing container.

The storage volume may be further configured to store solid form bodies in a particular orientation with respect to a direction in which they are moved after removal. Flierzu may be provided within the supply volume guide ribs or webs, which with corresponding

Recesses in the solid-form bodies correspond. In solid moldings with a non-rotationally symmetrical shape, the storage volume can also be adapted to the non-rotationally symmetrical shape, so that the

Orientation of the solid-form body is defined during the removal.

The recess or punching of the closure piece may be arranged according to the solid-shaped body in the defined orientation

take. This embodiment may be advantageous if solid-form body are provided with one or more predetermined breaking points and a dosage of parts of solid-shaped bodies takes place.

In one embodiment, the device and the reservoir are adapted to guide the closure piece along a trajectory which is a first

Section has, which serves for conveying a solid-form body or a part thereof in the mixing container, and which also has a second portion which serves for conveying a solid-form body or a part thereof in another container. The further container accommodates solid form body or parts thereof, which are not used for the preparation of the solution.

The first and second portions of the trajectory may be separated by the first position on the trajectory. Starting from the first position, therefore, a solid form body or parts thereof can be conveyed by conveying along the first portion of the trajectory in the mixing container, for example. In a first direction. If the solid-form body in the other container it is to be promoted, starting from the first position, along the second section of the trajectory, for example, in a direction opposite to the first direction or in a direction transverse thereto.

The closure piece can be moved by the actuator of the device in a linear or curved movement along the trajectory. The linear or

Curve movement may lie in a plane which is substantially perpendicular to a vertical axis of the recorded in a receptacle of the device

Reservoir is located.

The reservoir may be further configured to be within the

Reservoir volume stored solid form body to apply a force directed in the direction of the opening. This can be done for example by appropriate spring means or pressurized fluids. Alternatively or additionally, the storage volume may comprise a device which is permeable at least to gaseous fluids and which couples a space formed by a removed solids mold to an ambient atmosphere. This device may have a possibly equipped with a filter ventilation opening, a

fluid-permeable membrane or the like.

The reservoir can also at least in one area of the

Reservoir volume have a transparent or translucent area, a visual or optical control or detection of a level of the

Reservoir or at least a detection of a falling below a predetermined level allows. The optical control can take place by means of optical sensors, for example a camera or one or more light barriers, which emit a signal representing the fill level or falling below the predetermined fill level. Alternatively or additionally, the

Reservoir be adapted to emit an electrical, the level or below the predetermined level representing signal. For this purpose, for example, one or more electrical contacts may be provided at different locations within the storage volume, or a capacitive or ultrasonic sensor, or the like. The device can be used for the production of any solutions in which the concentration of individual ingredients must be set individually or over a time course variable. In particular, the device is suitable for the production of medical solutions, for example in the treatment of acute or chronic renal diseases used dialysis fluid (dialysate).

Hereinafter, a method of preparing a solution using the apparatus described above will be described. It gets away from it

assumed that the mixing vessel already contains a certain amount of solvent, for example. Water. The water e.g. can be present as ultrapure water, which was obtained by filtration or other methods from tap water. But it is also conceivable that initially one or more solid-form body are introduced into the mixing vessel before the solvent is supplied.

First, the device must be prepared by one or more

Reservoir can be used in designated recordings. The coding recognition device of the device is driven in this context to detect the onset of the reservoir and / or to recognize and evaluate the machine-evaluable coding of the reservoir or. The

Thus, coding is detected at, during, or after the insertion of a reservoir, and corresponding signals describing and representing the contents of the reservoir are generated and provided for use in a control unit. After the detection and detection is known in which

Storage container solid form body with which ingredients are stored, or in which order different solid-shaped body in one

Storage tanks are stored. The device is also driven to receive a signal which conveys information about a volume of the solvent used to prepare the solution contained in the mixing vessel. This signal can be received via a user interface, but it is also possible to generate a corresponding signal by means of a measuring device and to transmit it to the device. Suitable measuring devices are, for example, flow rate meters which determine an amount or a corresponding volume introduced into the mixing container and, if appropriate, an amount or a corresponding volume taken therefrom. or measuring devices for determining a weight of the mixing container or after deduction of the known own weight of the mixing container and optionally below

Consider the specific gravity of the solvent to determine the amount of solvent in the mixing vessel. Other measuring means comprise floats coupled to a transducer or transducer, which detect the liquid level in the mixing tank, which exceeds the known one

Geometry of the mixing container or its course over the filling level

Determination of the volume contained therein. Instead of one or more floats can also be a determination of the liquid level by means of sound waves, light rays or generally with electromagnetic radiation. It is also possible to determine the amount of solvent by identification of the mixing container and to provide a corresponding signal. This is, for example, then possible if with a certain volume or a certain amount

Solvent prefilled mixing container can be used.

The device is further driven to receive a signal representing a target composition of the final solution. The signal may, for example, be received via a user interface or a communication interface providing a communication link to a computer.

To prepare the solution, the device is driven, one or more solid-form body or parts thereof from one or more of the in the

Device used to promote storage tank in the mixing container. The supply of parts of solid-form bodies can be done by dividing whole solid-form body and selectively supplying some parts or discarding other parts. When stored in a reservoir different solids moldings can be promoted selected in the mixing container, while others, not required for the preparation of the solution can be conveyed into another container. The selection and quantity of the solid form or parts thereof conveyed to produce a solution in the mixing container depends on the desired composition and concentration of the

Solution. In one embodiment of the device is a mixing container for a one-time

Intended use, and already filled with a basic amount of substances required for the preparation of solutions. The addition of the same or additional substances beyond the basic quantity in order to produce a desired solution is carried out by appropriate control of the device, analogous to the manner described above. In this case, the device is set up and is actuated to receive signals which contain information about respective used mixing containers with different basic quantities.

represent different substances. The signals can be transmitted via a

User interface to be received, or by detecting and reading a machine-readable coding connected to the mixing container. The

Knowledge of the existing in a respective mixing container basic amount of substances makes it possible to determine the necessary amount of substances to be added and to control the device accordingly.

In one embodiment of the apparatus, a certain amount of the prepared solution is withdrawn from the mixing vessel continuously or at intervals.

Accordingly, the withdrawn amount can be replaced continuously or at intervals by adding solvents and solid-shaped bodies in an appropriate amount and composition. For this purpose, the device can have one or more measuring devices which determine the composition of the solution contained in the mixing container or of the solution taken out. The signals generated by the one or more measuring devices are supplied to a control unit of the device, which compares the actual composition of the solution with a target composition and controls the supply of solid-form bodies and / or solvent accordingly. Starting from a known starting composition and quantity, information about a withdrawn amount of the solution may also be used, the necessary amount of the solvent to be fed, and the type and number of added ones

Determine solids moldings and generate corresponding signals which are supplied to the control unit of the device.

The possibility of introducing different ingredients separately is with the device described above and the corresponding method the Preparation of a solution with a large variation of the concentration of different substances in the solution possible.

If the device is located directly at the location of use of the solution, this simplifies logistics and warehousing because no finished solutions having different compositions need to be stored. Moreover, it is possible for an even greater number of different uses or

Use cases to provide individually composed solutions.

Another advantage of the present apparatus and method is the possibility of adapting a solution in the course of use, for example, adjusting the composition of dialysate during one

Dialysis treatment to the needs of the patient. Thus, for example, by dialysis from the blood circulation of the patient removed potassium, which can lead to an undesirable change in the heart rate of the patient, be supplied by a corresponding adjustment of the potassium concentration of the dialysate, or with timely detection of impending sinking of the

Potassium level can this by appropriate adjustment of the

Potassium concentration of the dialysate can be counteracted early.

Short description of the drawing

The device will now be described with reference to the drawings. In the drawing shows

Fig. 1 is a first schematic representation of an exemplary device for

Production of a solution,

2 shows a first exemplary selection of forms of receptacles for

Storage container with means for detecting a coding of stored therein storage containers,

Fig. 3 a) -d) Examples of a detection of right or wrong in shots after

Figure 2 used storage containers,

4 shows a further exemplary receptacle with devices for detecting a coding of storage containers accommodated therein, 5 shows examples of a recognition of storage containers used in the receptacle according to FIG. 4, FIG.

6 shows a further exemplary receptacle with devices for detecting a coding of storage containers accommodated therein,

Fig. 7 schematic representations of storage containers with variants

machine-readable encodings,

8 shows components of a first exemplary example of a

ejector,

9 the ejector unit from FIG. 8 in different working positions, FIG.

10 is a second exemplary ejector unit,

11 shows components of a third exemplary example of a

ejector,

12 the ejector unit from FIG. 11 in different working positions, FIG.

13 is a first schematic representation of a device that allows feeding or discarding a solid form body or a part thereof, in two stages,

Fig. 14 is a second schematic representation of a device, a

Discarding a solid-form body or a part thereof,

Fig. 15 is a schematic representation of the apparatus of Figure 14 in the

Feeding a part of a solid-shaped body and discarding another part,

16 is a first schematic representation of the supply of a part of a

Solid-form body in two stages,

17 shows the essential steps of two alternative exemplary methods for producing a solution by means of the device, and

Fig. 18 is a second schematic representation of an exemplary apparatus for preparing a solution.

In the figures, the same or similar elements may be used with the same

Be referenced.

Description of exemplary embodiments FIG. 1 shows a schematic representation of an exemplary device 100 according to the invention for producing a solution. The apparatus 100 comprises a mixing tank 102 with an inlet 104 and a drain 106. Via the inlet 104, a solvent can be introduced into the mixing tank 102, and via the drain 106, a prepared solution can be supplied for use. In the figure, the mixing container 102 is filled up to a lower edge of the inlet 104 with a liquid solvent, indicated by the wavy lines drawn surface 108. A cover part 110 - in the figure from the mixing container 102nd

spaced apart - has four shots 112-115, in which

Reservoir 120-123 are used. Shots 112-115 are represented in the figure by the squares shown in perspective and are not detailed. From the storage tanks 120-123 solid molded bodies (not shown in the figure) stored therein can be selectively taken out and conveyed into the mixing tank 102. The conveyed into the mixing container 102 solid-form body dissolve in the mixing container 102 contained

Solvent, thus creating a solution with a desired

Composition. If the solution has a desired composition, it may be withdrawn via drain 106 and put to use. Inlet 104 and / or outlet 106 may also be connected to the cover part 110, for example via hoses or tubes which lead into or out of the mixing container.

A control circuit not shown in the figure comprises one or more

Processors, random access memory and non-volatile memory, which computer program instructions retrievably stores, which is a control program for

Make a solution by means of the device. The control circuit and associated components may be disposed in or on the lid portion 110. Also not shown in the figure are means for detecting a to the

Storage containers 112-115 provided coding, which provides information about the stockpiled in the respective storage containers 112-115 solid-form body mechanically readable.

FIG. 2 shows a first exemplary selection of forms of receptacles 200 for receptacles (base molds) with coding recognition devices 202 for Recognition of a coding of stored therein storage containers. The receptacle 200 shown on the left in the figure has an octagonal plan, which for receiving a corresponding octagonal base part of a

Reservoir is provided. The devices 202 may, for example, be simple switches which have a different state when a storage container is used, for example closed, than when the storage container is not in use, for example open. Instead of simple switch can also be a magnetic switch or a

Be provided light barrier, or the like, provide the corresponding signals.

The receptacle 200 shown in the figure in the middle has a round

Cross-section, which is provided for receiving a corresponding round base part of a reservoir. In this recording, only one device 202 is provided, as will be explained below with reference to FIG.

The receptacle 200 shown in the figure on the right has a square

Cross-section on which for receiving a corresponding square

Base part of a reservoir is provided. In this recording, as in the octagonal, two devices 202 are provided.

FIG. 3 shows examples of a recognition of storage containers used correctly or incorrectly in the base according to FIG.

In part a) of Figure 3 storage containers are used with the correct base parts in the respective images, represented by the corresponding shapes with slightly smaller dimensions than those of the recordings. In the left receptacle 200 is thus a reservoir with an octagonal base part

taken in the middle one with a round base part, and in the right one with a square base part. The signal state of the respective

Devices 202 are changed from a signal state when no reservoir is received, for example, all are in a respective receptacle

arranged switch now closed. The coding of the contents of

Reservoir takes place via the shape of the base part, ie in a reservoir with a base part of a certain shape are solid-shaped body with certain Ingredients and possibly stored in a specific concentration. For the

Identification of the ingredients it is sufficient to recognize the insertion of a reservoir with the properly shaped base. The coding on the shape of the base part also has the advantage for the operator that the right receptacle for a storage container is easily recognizable; In addition, a color coding can be provided. A predetermined by the shape of the respective record order of the reservoir can in some embodiments of the

Device advantageous.

In part b) of FIG. 3, a storage container with a round base part is inserted into each of the receptacles. Into the shots with an octagonal or a

square cross-section is therefore used a wrong reservoir. In the octagonal recording only the signal state of the device 202-1 is changed by the round base part, that is, for example, a corresponding switch is closed. Device 202-2 is arranged so that the round base part of the storage container used does not change its signal state. It can therefore be seen that a reservoir with a non-octagonal base part was used and it can be generated a corresponding signal. The signal may be used to alert the user that a reservoir not intended for this receptacle has been used.

In the receptacle with the round cross section, a reservoir is used with the correct base part; here there is no change compared to part a) of FIG.

The storage container with the round base part inserted into the receptacle with the square cross-section causes the signal state of the device 202-3 to be changed, for example a corresponding switch is now closed, but not the signal state of the device 202-4. It can therefore be seen that a reservoir was used with a non-square base part and it can be generated a corresponding signal. Again, the signal may be used to alert the user that a reservoir not intended for that receptacle has been used. In part c) of Figure 3, a similar situation is shown as in part b). Notwithstanding the situation described above are here reservoir with a

octagonal base part in the photographs with the octagonal or the

square cross section used. The octagonal base does not fit into the receptacle with the round cross section, as indicated by the dashed line representation. As previously described for the case of a round base reservoir, inserting a octagonal base reservoir will only change the signal state of the square section device 202-3, and the signal state of the device 202-4 will remain unchanged. It can therefore be seen that a reservoir was used with a non-square base and it can be a

corresponding signal can be generated. Again, the signal may be used to alert the user that a reservoir not intended for that receptacle has been used.

In part d) of Figure 3, again, a similar situation is shown as in part b). Notwithstanding the situation described above here is a reservoir with a square base part inserted into the receptacle with the square cross-section. In the photographs with the octagonal or round cross section, the square base part does not fit into, as by the representation with a

dashed line is indicated. Here only the correct insertion of a reservoir with square base part can be detected in the corresponding recording.

FIG. 4 shows another exemplary receptacle 400 with means 402-1, 402-2 and 402-3 for detecting a coding of data recorded therein

Reservoirs. In contrast to the recordings described above, only one receptacle 400 with a single cross-section is provided, but in which there are three means 402-1, 402-2 and 402-3 for recognizing a coding of receptacles received therein instead of one or two. The devices 402-1, 402-2 and 402-3 are arranged in the receptacle 400 in such a way that it is possible to detect reservoirs with different base parts. When a

Device for producing a solution has a plurality of such recordings So a fixed order or position of the storage container used in relation to the arrangement of recordings not required.

The recognition of different storage containers with different base parts will be explained with reference to FIG. In part a) of FIG. 5, a storage container with an octagonal base part is inserted into the receptacle 400. The signal states of the devices 402-1 and 402-2 are changed from a signal state when no reservoir is received, for example, corresponding switches are now closed. The signal state of the device 402-3 is unchanged.

In part b) of Figure 5 is a reservoir with a round base in the

Recording 400 used. The signal state of the device 402-1 is compared to a signal state when no reservoir is added, changed, for example, a corresponding switch is now closed. The signal states of the devices 402-2 and 402-3 are unchanged.

In part c) of FIG. 5, a storage container with an octagonal base part is inserted into the receptacle 400. The signal states of all devices 402-1, 402-2 and 402-3 are against a signal state when no reservoir

is received, changed, for example, corresponding switches are now closed.

In part d) of FIG. 5, a storage container with a square base part with cutouts in the receptacle 400 is inserted. The signal state of the device 402-2 is compared with a signal state when no reservoir is added, changed, for example, a corresponding switch is now closed.

The signal states of the devices 402-1 and 402-3 are unchanged.

In part e) of Figure 5 is another reservoir with a square

Base part with recesses inserted into the receptacle 400. The signal states of the devices 402-2 and 402-3 are changed from a signal state when no reservoir is accommodated, for example, corresponding switches are now closed. The signal state of the device 402-1 is unchanged. From the combination of the signal states of the devices 402-1, 402-2 and 402-3 may be based on the shape of the base part of a stored reservoir

be closed, and with clear allocation of the shape of the base part to a content of the reservoir also on the content.

FIG. 6 shows a further exemplary receptacle 600 with means 602 for detecting a coding of storage containers accommodated therein. In this example, there are eight means 602 for detecting a coding of reservoirs received therein along one side of the receptacle

arranged square section. The devices 602 are through the

By way of example, rectangles are represented, some of which are filled black and some are shown without filling. The devices may e.g. Include switches, which each assume an open and a closed state and thereby can represent a binary code in their entirety.

In the receptacle 600, a reservoir 604 is used, represented in the figure by the inner frame. The base part of the storage container 604 is provided on the side facing the devices 602 with recesses 606, which bring in the inserted state lying in the region of the indentations means 602 in a first state. In areas outside the indentations 606 devices are brought into a second state. If the

Means may include switches in the region of the indentations, for example, be open, and lying in areas outside the indentations

closed. In the figure, this is due to the different filling of the

Devices 602 representing rectangles shown. The encoding shown by way of example in the figure by the eight devices 602 can be represented in binary form as 01100010; In total, 256 different codes can be represented with the eight devices 602 of FIG.

FIG. 7 shows schematic representations of storage containers 700 with further exemplary variants of machine-readable codes. In part a) of the figure, a machine-readable bar code 704 is attached to the base part 702 of the storage container 700. Bar code 704 can be read by a reading device (not shown in the figure) placed in the corresponding receptacle at insertion or in the inserted state and the information contained therein representative signal may be a control device of the device for

Preparation of the solution to be supplied. Bar code 704 can also be read out with a reading device not arranged in the receptacle, for example a movable reading device which is signal-connected to the device for producing the solution, or a reading device arranged in a certain region of the device for producing the solution. By means of such a reading device, the bar code 706 can also be read out,

expediently before inserting the storage container into the corresponding receptacle. In this case, recognizing the insertion of a reservoir into a receptacle may be required to determine from the sequence of readings of the reservoir

Barcodes and detecting the insertion of the reservoir into the receptacle to create an association of recording and reservoir or contents of the reservoir. In part b) of the figure, the bar codes are replaced by two-dimensional codes 710, 712, represented in the figure by QR codes. The above statements on recognition and assignment apply accordingly.

FIG. 8 shows components of a first exemplary example of a

Ejector unit of a storage container of the device for producing a medical solution. In the left part of the figure is a plan view of a

Reservoir 800 with a base portion 802 and a storage volume 804 can be seen. The storage volume 804 has two webs 810 arranged on the inside, which serve to position solid moldings stored in the storage volume in relation to the base part 802. Reservoir volume 804 is open on the underside, ie on the side that abuts the base part 802. The basic part 802 shown by way of example in the figure is a right-angled parallelepiped (cuboid) open on the left and right side, similar to the shell of a box

Matchbox. The dashed lines on the top and bottom of the base part represent the inner boundaries of the side walls of the cuboid. The dashed area on the right side of the base part is a

Recess 812 in the lower surface of the base part, through which an actuator of the device for producing a solution (not shown in the figure) with the

Ejector unit can be coupled. In the hollow base portion 802 of the reservoir 800, a closure piece 814 is movably inserted, shown in the figure on the right side. The arrow shows the direction in which the closure piece 814 in the base part 802 is insertable. Closure piece 814 has in the base 816 a recess or punching 818, in which a solid-shaped body can be accommodated. The recess or punching 818 has two projections 820, which correspond in a certain position of the closure piece 814 to the storage volume with the webs 810 of the storage volume and hold a recorded solid-shaped body in a defined position. It should be noted that the ejection unit can also be designed without the webs 810 and projections 820. On the right side of the closure piece 814 is a

Dovetail-shaped recess 822 arranged, in which an actuator of the device (not shown in the figure) from below through the recess 812 is insertable.

Figure 9 shows the ejector unit of Figure 8 in different working positions. In part a) of the figure, the closure piece 814 is displaced from a central position to the right out of the base part 802 of the storage container 800. Base member 802 is connected to an actuator 830 in the example by means of a dovetail connection such that a forward and backward movement of actuator 830 in a plane is transferred to the closure piece 814. The actuator 830 opposite part of the body 816 of the closure piece 814 is located in the area in which the opening of the storage volume 804 is located and blocks it, so that no solid-form body can escape from the storage volume 804. An optionally previously recorded in recess or punching 818 of the body 802 solid-shaped body (not shown in the figure) is moved by plug 814.

In part b) of the figure, the closure piece 814 is displaced from a central position to the left from the base part 802 of the storage container 800. In this position, the area of the body 816 of the closure piece connected to the actuator 830 and the actuator 830 itself block the opening of the storage volume 804, so that no solids form body from the storage volume 804

can get out. An optionally previously recorded in recess or punching 818 of the body 802 solid-shaped body (not shown in the figure) is moved by plug 814. A recorded in recess or punching 818 of the body 802 solid-form body can be pushed out of the base portion 802 of the reservoir 800 upon further displacement to the left or right and out of the recess or punched out 818 there. Depending on the design, a shift in a first direction in a recess or punching 818 of the base body 802 recorded solid-form body in a

Promote mixing vessel, and a shift in another direction can be used to promote the solid-form body in another container.

FIG. 10 shows a second schematic representation of an exemplary one

Ejector unit of a storage container 800-1, which represents a modification of the ejector unit described in FIG. In the modification, actuator 830-1 has a width that corresponds to that of the closure piece 814-1.

Flierdurch improved blocking of the opening of the storage volume 804- 1 can be achieved, which also provides better protection of remaining in the storage volume 804-1 solid-form body. In addition, main body 816-1 has a slot on the side opposite to the actuator 830-1 side, in which can engage in the figure, not shown deflection means which a solid molded body or parts thereof in a certain direction from the

Distract the shift plane.

FIG. 11 shows a second schematic representation of components of a third exemplary example of an ejection unit of a storage container 1100. The components shown in the figure essentially correspond to those described with reference to FIG. In contrast, on the left side of the base part 1102 two further recesses 1140 and 1142 are provided in the lower surface of the base part, can be coupled by the coupling elements of an extension element with corresponding coupling elements 1144 and 1146 of closure piece 1114.

FIG. 12 shows components of the ejector unit of the storage container 1100 shown in FIG. 11 with coupled extension element 1150 in FIG

different positions. Extension member 1150 has

Dovetail coupling elements 1152 and 1154, which in the Coupling elements 1144 and 1146 of the closure piece 1114 engage. It should be noted that in the ejector unit shown in this figure, but also in other variants presented in this description, instead of the

Dovetailed connections and other connections are possible, for example. By means of differently shaped form-fitting releasably interlocking

Coupling elements, or by means of magnets or electromagnets or the like. It is also possible to bring an actuator without coupling in contact with the closure piece and to be active only in one direction. A movement in the other direction can be effected, for example, by a spring force acting on the side of the closure piece opposite the actuator.

In part a) of the figure, the closure piece 1114 is pulled by actuator 1130 from a middle position to the right. Extension element 1150 is connected by means of the coupling elements 1152 and 1154, which engage in the coupling elements 1140 and 1142 of the closure piece, with this. Due to the connection of closure piece 1114 and extension element 1150 is the

Extension element has also been pulled to the right and blocks the opening of the storage volume. Also shown in the figure is a slot 1156 which engages around a deflection unit not shown in the figure. The function of the deflection unit will be described elsewhere.

In part b) of the figure, the closure piece 1114 has been moved to the left by actuator 1130 from a middle position. Due to the connection of closure piece 1114 and extension element 1150, the extension element has also been moved to the left. The opening of the storage volume is now partially blocked by the closure piece 1114, in part by the actuator 1130.

Figure 13 shows a first schematic representation of a device 100, which allows feeding or discarding a solid form body or a part thereof, in two stages.

In part a) of the figure is a solid-shaped body 1360 in the recess or

Punching received 1318 of the closure piece 1314 of the ejector unit. Further solid-form body 1360 are stored in the storage volume of the reservoir 1300. Closure piece 1314 and solid-form body 1360 are moved in the direction of the arrow. In this case, deflection unit 1370 engages in the slot of the closure piece 1314. In the illustration, the solid-form body 1360 abuts the deflector 1370. The deflection unit 1370 is for example a wedge or triangular part of a feed channel 1380, which leads to an addition opening of the mixing container, not shown in the figure. Also shown in the figure is a transparent or translucent region 1390 on the storage container 1300, which enables optical control of the filling level.

In part b) of the figure, molded solid bodies 1360 and closure piece 1314 are moved further in the direction of deflection unit 1370. Deflection unit 1370 has blocked the movement of solid-form body 1360 and causes this to a

Breaking point is broken. The broken part falls into the feed channel 1380.

In supply channel 1380 a switchable between two outputs switch 1381 is provided. One of the outputs leads to the one not shown in the figure

Mixing container, the other in a likewise not shown further container, which does not accommodate the Fierstellung the solution used solids form body or parts thereof.

In part b) of the figure, only a part of the solid-shaped body 1360 initially passes into the feed channel 1380. The other part is still in the recess or cutout 1318 of the closure piece 1314. If the closure piece 1314 is moved further to the left, the other part of the solid molded body 1360 will enter the feed channel and there by means of the switch 1381 either the mixing container or fed to the other container.

Figure 14 shows a second schematic representation of a device 100 which allows discarding a solid form body or a part thereof. in the

Reservoir volume of the reservoir 1300 solid form body 1360 are stored, one of which was taken in recess or punching 1318 of the closure piece 1314 and was moved to the right until it over the right feed channel 1380-2, which leads to the other container, from the Recess or punched out 1318 of the closure piece 1314 came out. In the same For example, a solid mold body 1360 received in recess or punch 1318 of plug 1314 may be moved to the left until it enters the left feed channel 1380-1, which leads into the mixing container. In the figure, a deflection unit 1370 is also shown, whose operation is explained with reference to FIG. In this embodiment of the device in the feed channel 1380-1 no switch is required. Feeding or discarding takes place by appropriate choice of the direction in which the solid-shaped body 1360 is moved until it comes out of the closure piece 1314.

Figure 15 shows a schematic representation of the device 100 of Figure 14 in the supply of a portion of a solid-form body 1360. The promotion of the solid-form body 1360 is carried out as, for example, with reference to Figure 14 described. Similarly as described with reference to Figure 13, a solid-shaped body 1360 is broken at deflector 1370 and enters the left feed channel 1380-1 which leads into the mixing container. A remaining part of the solid-form body 1360 is conveyed into the right feed channel 1380-2, through which it passes into the other container.

FIG. 16 shows a schematic illustration of another embodiment of the device 100 of FIG. 13. In this embodiment, the deflection unit 1670 is changed from that of FIG. Instead of pressing the solid-shaped body against a fixed wedge until it breaks at the predetermined breaking point, in this embodiment, the closure piece 1314 is pressed against a rotatably mounted about a deflection unit 1670, which has a force acting substantially perpendicular to the direction of displacement on the Solid-form body 1360 exercises. In part a) of the figure, the closure piece 1314 just comes in contact with the

Deflection unit 1670. In part b) of the figure, the deflection unit 1670 has already broken the solid molded body 1360 at the predetermined breaking point. The deflection unit 1670 is shown for simplicity in the figure only schematically as part of a circle with stop surfaces, which with the closure piece 1314 and

Solid form body 1360 come into contact. The arrow shows the direction of the rotation caused by the displacement of the stopper 1314. In part b) of FIG. 16, a comparable situation as in part b) of FIG. 13 is shown. Deflection unit 1670 has the linear movement of closure piece 1314 in a rotational movement implemented, and the upper part of the deflector presses on the solid-shaped body 1360 and has this broken at the predetermined breaking point.

FIG. 17 shows exemplary flow diagrams of the essential steps of two alternative exemplary methods 1700 for establishing a solution by means of the device.

In part a) of the figure, the coding of a

Reservoir read, which contains information about the contents of the solid form contained therein body and possibly an order in which solid form body with different ingredients and / or concentrations thereof can be removed. In step 1720, the insertion of the reservoir into a corresponding receptacle of the device is detected and a signal indicating the detection is generated and provided. The signal can also be a

Identification of the recording included when the device has multiple shots. In step 1730, a linking of contents of the storage container and the identification of the recording takes place accordingly. In step 1740, the device receives a desired composition of the solution to be prepared, and in step 1750, information about the amount and properties of the solvent. Not only the type of solvent itself, but also an already existing basic mixture with certain ingredients, falls under Properties. From the information available, the device calculates in step 1760 the amount and, if necessary, the type of solids to be added to the solvent and controls the recording or the recordings of the device so that the

desired composition of the solution is achieved.

In part b) of the figure, steps 1710 and 1720 are interchanged with respect to part a). The device is configured to recognize the coding of a storage container already inserted into a receptacle. This can be done, for example, by an electrical or mechanical coding contained in a base part of the storage container, or by an optical recognition of a coding or a recognition of the coding by electromagnetic waves at short distances. The detection of the insertion and the coding can essentially take place at the same time, but this is not absolutely necessary, for example if only one actuator is required for actuation an ejector is provided, and different reservoirs are individually sequentially connected to the actuator. The remaining steps are already described with reference to part a) and will not be explained again here. FIG. 18 shows a plan view of a second schematic representation of an exemplary device 1800 for producing a solution. At this

For example, only one actuator 1810 is provided for actuating an ejector (not shown in the figure) of a reservoir 1820. For the

Preparation of the solution is in each case one of a plurality of rotatable on a carousel 1830 arranged reservoirs 1820 in a position aligned with the actuator 1810 position. In this position, the actuator 1810 may actuate the ejector of the reservoir 1820 to remove one or more solids or parts thereof from the reservoir 1820 and convey them into the mixing container 1840. Actuator and ejector may be the same or similar design and function the same or similar as described above.

LIST OF REFERENCE NUMBERS

100 device

102 mixing containers

104 inlet

106 Procedure

108 Solvent

1 10 cover part

112-115 Storage for storage tank

120-123 storage tank

200 intake for storage tank

202, 202-x Coding Recognition Device 402, 402-x Coding Recognition Device 600 Reservoir Reservoir 602 Coding Recognizer 604 Reservoir

606 indentations

700 storage tanks

702 base part

704, 706 bar code

710, 712 QR Code

800, 800-x reservoir

802 base part

804, 804-x storage volume

810 footbridge

812 recess

814, 814-x locking piece

816, 816-x basic body

818 recess / punching

820 lead

822 recess

830, 830-x actuator

1100 storage containers

1102 base part

1114 stopper 1 130 actuator

1 140, 1 142 recess

1 144, 1 146 coupling element

1 150 extension element

1 152, 1 154 coupling element

1 156 slot

1300 storage tanks

1314 stopper

1318 recess / punching

1360 solid moldings

1370, 1670 deflection unit

1380, 1380- x feed channel

1381 switch

1390 transparent / translucent area

1700-1760 Procedures & Procedures

1800 device

1810 actuator

1820 reservoir

1830 carousel

1840 mixing container

Claims

claims

An apparatus (100) for producing a medical solution by adding solids in solid form (1360) to a solvent (108) comprising:

- A mixing container (102) via an inlet (104) with a

Solvent (108) can be filled, and from which via a drain (106), the solution can be supplied to a use, and also having an addition opening, through which the solid-form body (1360) are introduced into the mixing container (102), such as

a metering device for the controllable selective addition of solid moldings, or parts thereof, with different ingredients and / or different concentrations of ingredients from one or more storage containers stored in one or more corresponding receptacles (112-115) of the device (100) ( 120-123), in which the

Solid form body (1360) are removably stored.

The apparatus (100) of claim 1, further comprising:

a code recognition means (202; 202-x) for recognizing and

Evaluating a machine-evaluable coding connected to a storage container (120-123) which contains information about which ingredients are contained in the solid-form containers stored in the respective storage container.

The apparatus (100) of claim 2, wherein the encoder recognizer (202; 202-x) comprises:

Means for recognizing that a storage container (120-123) is inserted in a receptacle (112-115), wherein the coding which can be evaluated by machine takes place by a shaping of the receptacle which only accommodates receptacles with a corresponding shape of the part to be picked up by the receptacle, and or

- A reading device for reading an optical (704, 706, 710, 712) or electrical coding.

The apparatus (100) of claim 1, 2 or 3, wherein each of the receptacle receptacles includes an actuator (830; 830-x; 1130) releasably connected to an ejector unit of a receptacle to be received by the receptacle

Reservoir is coupled, wherein the releasable connection allows at least in one direction, a power transmission of the actuator to a movable closure piece (814; 814-x) of the ejector unit.

5. Device (100) according to one or more of the preceding claims 1 to 4, further comprising:

- one or more units to ensure the promotion of

Solid-form bodies at an opening of one or more with the

Device coupled reservoir.

6. Device (100) according to one or more of the preceding claims 1 to 5, wherein the mixing container (102) is a disposable mixing container, further comprising:

- A folder for removable recording of the disposable mixing container.

The apparatus (100) of claim 6, further comprising:

- A guide device, which with the insertion of the disposable mixing container in the device, the inlet, the drain and / or the

Addition opening of the disposable mixing container automatically connects with corresponding terminals or openings of the device or this aligns each other so that their function is ensured.

8. Device (100) according to one or more of claims 1 to 7,

also comprising:

a meat device for heating the mixing container,

a device for generating a flow in the mixing container, and / or

- A device for introducing a gas into the mixing container.

9. Device (100) according to one or more of claims 1 to 8, wherein the metering device, a selection device, by means of which solid Shaped body (1360) or parts thereof can optionally be promoted in the mixing container (102) or in another container.

10. Device (100) according to claim 9, wherein the selection device has a switch (1381) arranged before being fed into the mixing container or an ejector arranged before being fed into the mixing container, or wherein the closure piece has an extended conveying path over the one Solid form body or parts thereof are conveyed into the other container.

The device (100) according to one or more of the preceding claims 4 to 10, further comprising:

a baffle (1370, 1670) which comes into contact with the solid-form body (1360) when the closure piece (1314) after the

Removal of the solid-form body from the reservoir has traveled a certain first distance in a first direction, wherein the

Deflecting body at least on a part of the solid-shaped body exerts a force acting in a second direction, which points out of a first plane in which lies the first direction.

12. Device (100) according to claim 11, wherein the deflecting device is adapted to exert a force on the body of solids on contact, which causes a breaking off of at least first parts of the solid-form body, wherein the metering device or the closure piece are designed in this way in that second parts of the solid-form body are not or only slightly movable in the second and / or an opposite direction.

13. Device (100) according to claim 11 or 12, wherein the closure piece

is set, a certain orientation of the solid-shaped body with respect to the first direction during movement to the

Ensure deflector.

14. Device (100) according to one or more of the preceding claims, wherein a detection device is provided, which took place Provision of a solid-form body in the metering device

signaled.

15. Device (100) according to claim 14, wherein the detection device is set up for optical and / or electrical detection and / or for detecting a weight, a change in weight and / or a mechanical impulse.

16. Reservoir (120-123; 700; 800) of a device according to one of

Claims 1 to 15, comprising:

- A storage volume, the solid-shaped body receives in a defined arrangement, and having an opening through which solid-form body can be removed,

an ejector unit disposed on the opening releasably coupleable to an actuator of the apparatus, the ejector unit comprising a shutter (814; 814-x) movably guided along a predetermined trajectory, which releases the opening in a first position to the extent that one the stored in the reservoir solids form body can pass through the opening of the reservoir into a conveyor track, and which blocks the opening of the reservoir in one or more positions not corresponding to the first position along the trajectory,

a machine recognizable, readable and / or evaluable coding which contains information about which ingredients in the in the

Reservoir stored solids-form bodies are included.

17. Reservoir (120-123; 700; 800) according to claim 16,

- wherein the closure piece comprises a component which forms a space for receiving a solid-shaped body and at least one region for blocking the opening of the reservoir, and which has at least in the region for blocking the opening of the reservoir either a thickness which in Substantially corresponds to the thickness of the solid-shaped body to be metered, or its top in this area in the Substantially lies in a plane with the opening facing the highest elevation of a received in the component solid-shaped body.

The storage container (120-123; 700; 800) according to claim 16 or 17, wherein the trajectory along which the closure piece is guided has a first portion adapted to convey a solid form body or a part thereof into the mixing container Device is used, and has a second portion which leads to the carriage of a solid-form body or a part thereof in another container.

The storage container (120-123; 700; 800) of claim 18, wherein the first

Section and the second section are separated by the first position.

A reservoir (120-123; 700; 800) according to any one of claims 16 to 19, wherein the closure member is movable by the actuator in a linear and / or curve movement along the trajectory.

21. A storage tank (120-123; 700; 800) according to any one of claims 16 to 20, wherein the storage volume for positioning the solid molded body is arranged with respect to a direction in which the solid molded body moves out of the storage tank after being taken out become.

22. Reservoir (120-123; 700; 800) according to any one of claims 16 to 21, wherein stored in the storage volume solid-form body are acted upon by a force acting in the direction of the opening and / or wherein the storage volume at least for gaseous fluids having permeable means for coupling a body formed by removed solid form space of the storage volume to an ambient atmosphere.

23. Reservoir (120-123; 700; 800) after one or more of

Claims 16 to 22, wherein at least a portion of the storage volume, a transparent or translucent area (1390) for visual or visual Has control of a level or to detect a shortfall of a predetermined level.

24. Reservoir (120-123; 700; 800) after one or more of

Claims 16 to 23, wherein the storage volume is a device for

Generation of a level representing electrical or optical signal.