EP3676377A4 - Testvorrichtungen und verfahren zur verwendung davon - Google Patents

Testvorrichtungen und verfahren zur verwendung davon Download PDF

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Publication number
EP3676377A4
EP3676377A4 EP18849787.9A EP18849787A EP3676377A4 EP 3676377 A4 EP3676377 A4 EP 3676377A4 EP 18849787 A EP18849787 A EP 18849787A EP 3676377 A4 EP3676377 A4 EP 3676377A4
Authority
EP
European Patent Office
Prior art keywords
methods
assay devices
assay
devices
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP18849787.9A
Other languages
English (en)
French (fr)
Other versions
EP3676377A1 (de
Inventor
Kirk M. Ririe
Aaron D. WERNEREHL
Christopher P. PASKO
Ali Laayoun
Carole Vachon
Agnes Dupont-Filliard
Laurent Mesta
Andrew C. Hatch
Erik W. HUYNH
David E. Jones
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biomerieux SA
Biofire Defense LLC
Biofire Diagnostics LLC
Original Assignee
Biomerieux SA
Biofire Defense LLC
Biofire Diagnostics LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biomerieux SA, Biofire Defense LLC, Biofire Diagnostics LLC filed Critical Biomerieux SA
Publication of EP3676377A1 publication Critical patent/EP3676377A1/de
Publication of EP3676377A4 publication Critical patent/EP3676377A4/de
Pending legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502761—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip specially adapted for handling suspended solids or molecules independently from the bulk fluid flow, e.g. for trapping or sorting beads, for physically stretching molecules
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00—Heating or cooling apparatus; Heat insulating devices
    • B01L7/52—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
    • B01L7/525—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples with physical movement of samples between temperature zones
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0647—Handling flowable solids, e.g. microscopic beads, cells, particles
    • B01L2200/0668—Trapping microscopic beads
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0689—Sealing
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/10—Integrating sample preparation and analysis in single entity, e.g. lab-on-a-chip concept
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/16—Reagents, handling or storing thereof
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0627—Sensor or part of a sensor is integrated
    • B01L2300/0636—Integrated biosensor, microarrays
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0816—Cards, e.g. flat sample carriers usually with flow in two horizontal directions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/087—Multiple sequential chambers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/18—Means for temperature control
    • B01L2300/1805—Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks
    • B01L2300/1811—Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks using electromagnetic induction heating
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/18—Means for temperature control
    • B01L2300/1805—Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks
    • B01L2300/1816—Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks using induction heating
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/18—Means for temperature control
    • B01L2300/1805—Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks
    • B01L2300/1822—Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks using Peltier elements
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/18—Means for temperature control
    • B01L2300/1805—Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks
    • B01L2300/1827—Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks using resistive heater
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/18—Means for temperature control
    • B01L2300/1838—Means for temperature control using fluid heat transfer medium
    • B01L2300/1844—Means for temperature control using fluid heat transfer medium using fans
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/043—Moving fluids with specific forces or mechanical means specific forces magnetic forces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0481—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure squeezing of channels or chambers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Clinical Laboratory Science (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Fluid Mechanics (AREA)
  • Hematology (AREA)
  • Dispersion Chemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Plant Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
EP18849787.9A 2017-08-31 2018-05-23 Testvorrichtungen und verfahren zur verwendung davon Pending EP3676377A4 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201762552588P 2017-08-31 2017-08-31
PCT/US2018/034208 WO2019045807A1 (en) 2017-08-31 2018-05-23 ANALYSIS DEVICES AND METHODS OF USE

Publications (2)

Publication Number Publication Date
EP3676377A1 EP3676377A1 (de) 2020-07-08
EP3676377A4 true EP3676377A4 (de) 2021-04-14

Family

ID=65527775

Family Applications (1)

Application Number Title Priority Date Filing Date
EP18849787.9A Pending EP3676377A4 (de) 2017-08-31 2018-05-23 Testvorrichtungen und verfahren zur verwendung davon

Country Status (5)

Country Link
US (2) US11691152B2 (de)
EP (1) EP3676377A4 (de)
JP (2) JP2020532720A (de)
CN (1) CN111295442A (de)
WO (1) WO2019045807A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2013202805B2 (en) * 2013-03-14 2015-07-16 Gen-Probe Incorporated System and method for extending the capabilities of a diagnostic analyzer
US20210123089A9 (en) 2018-06-07 2021-04-29 Biofire Diagnostics, Llc Rapid thermocycling methods
JP2024520922A (ja) * 2021-05-12 2024-05-27 コヨーテ バイオサイエンス カンパニー，リミテッド 試料処理装置及び試料処理方法
WO2024020414A1 (en) * 2022-07-22 2024-01-25 Biofire Diagnostics, Llc Cell lysis and nucleic acid recovery
WO2024020412A2 (en) * 2022-07-22 2024-01-25 Biofire Diagnostics, Llc Rapid cell lysis and nucleic acid recovery

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009002447A1 (en) * 2007-06-21 2008-12-31 Gen-Probe Incorporated Instrument and receptacles for use in performing processes
US20100056383A1 (en) * 2006-11-15 2010-03-04 Ririe Kirk M High density self-contained biological analysis
US20110318784A1 (en) * 2008-12-23 2011-12-29 Qiagen Gmbh Preparation and amplification of nucleic acids by means of magnetic particles
WO2016196827A1 (en) * 2015-06-02 2016-12-08 Biofire Defense, Llc Sample to sequence

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100523216C (zh) * 2001-03-02 2009-08-05 匹兹堡大学 Pcr方法
KR100601974B1 (ko) 2004-11-25 2006-07-18 삼성전자주식회사 비드의 상이한 레이저 흡수에 의한 핵산의 정제 장치 및방법
US7648681B2 (en) * 2004-12-01 2010-01-19 Meridian Bioscience, Inc. Specimen collection system
EP3556868A1 (de) 2005-05-09 2019-10-23 BioFire Diagnostics, LLC In sich geschlossene biologische analyse
AU2012200153B2 (en) * 2005-05-09 2012-09-27 Biofire Diagnostics, Llc Self-Contained Biological Analysis
CA2610294C (en) 2005-05-09 2023-10-03 Theranos, Inc. Point-of-care fluidic systems and uses thereof
KR100790880B1 (ko) * 2006-07-05 2008-01-02 삼성전자주식회사 자성 비드가 결합되어 있는 소수성 다공성 중합체가 벽면에결합되어 있는 마이크로채널 또는 마이크로챔버를포함하는 미세유동장치 및 그를 이용하는 방법
US20110223583A1 (en) 2008-11-24 2011-09-15 Early Warning Inc. Devices and methods for providing concentrated biomolecule condensates to biosensing devices
WO2010141921A1 (en) 2009-06-05 2010-12-09 Integenx Inc. Universal sample preparation system and use in an integrated analysis system
DE102012015063B4 (de) * 2012-07-31 2014-10-30 Sartorius Stedim Biotech Gmbh Vorrichtung und Verfahren zur Behandlung eines Filtrationsmediums
EP2965817B1 (de) * 2012-10-24 2017-09-27 Genmark Diagnostics Inc. Integrierte multiplex-zielanalyse
CN103849548A (zh) * 2012-12-03 2014-06-11 三星电子株式会社 用于扩增核酸的试剂容器及其制备方法、存储试剂的方法和用于核酸分析的微流体系统
US20140170667A1 (en) 2012-12-19 2014-06-19 Nanomr, Inc. Methods for amplifying nucleic acid from a target
US9460268B2 (en) 2013-09-06 2016-10-04 Theranos, Inc. Systems and methods for detecting infectious diseases
US20170152509A1 (en) * 2014-05-23 2017-06-01 Shimadzu Corporation Method for operating magnetic body particles and device for operating magnetic body particles
EP3209257A1 (de) * 2014-10-23 2017-08-30 Ibis Biosciences, Inc. Tupferschnittstelle für mikrofluidische vorrichtungen
JP2016093157A (ja) 2014-11-17 2016-05-26 セイコーエプソン株式会社 容器収納体
CN105799153B (zh) * 2014-12-30 2023-08-18 权星智控系统工程(上海)股份有限公司 一种医用消毒棉棒封口焊接装置及灌液机
AU2016297922C1 (en) * 2015-07-24 2022-04-21 Novel Microdevices, Inc. Sample processing device comprising magnetic and mechanical actuating elements using linear or rotational motion and methods of use thereof
US10875026B2 (en) 2016-02-22 2020-12-29 Biofire Defense, Llc Devices and methods for rapid PCR

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100056383A1 (en) * 2006-11-15 2010-03-04 Ririe Kirk M High density self-contained biological analysis
WO2009002447A1 (en) * 2007-06-21 2008-12-31 Gen-Probe Incorporated Instrument and receptacles for use in performing processes
US20110318784A1 (en) * 2008-12-23 2011-12-29 Qiagen Gmbh Preparation and amplification of nucleic acids by means of magnetic particles
WO2016196827A1 (en) * 2015-06-02 2016-12-08 Biofire Defense, Llc Sample to sequence

Also Published As

Publication number Publication date
EP3676377A1 (de) 2020-07-08
JP7423696B2 (ja) 2024-01-29
CN111295442A (zh) 2020-06-16
US11691152B2 (en) 2023-07-04
US20240123452A1 (en) 2024-04-18
US20200261914A1 (en) 2020-08-20
WO2019045807A1 (en) 2019-03-07
JP2020532720A (ja) 2020-11-12
JP2022141654A (ja) 2022-09-29

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Inventor name: VACHON, CAROLE

Inventor name: LAAYOUN, ALI

Inventor name: RIRIE, KIRK M.

Inventor name: PASKO, CHRISTOPHER P.

Inventor name: JONES, DAVID, E.

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