EP3651858A1 - Utilisation d'électrolytes dans des préparations cosmétiques pour la réduction sélective d'une population de micro-organismes sur la peau humaine - Google Patents

Utilisation d'électrolytes dans des préparations cosmétiques pour la réduction sélective d'une population de micro-organismes sur la peau humaine

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Publication number
EP3651858A1
EP3651858A1 EP18731075.0A EP18731075A EP3651858A1 EP 3651858 A1 EP3651858 A1 EP 3651858A1 EP 18731075 A EP18731075 A EP 18731075A EP 3651858 A1 EP3651858 A1 EP 3651858A1
Authority
EP
European Patent Office
Prior art keywords
electrolytes
salts
cosmetic
oil
cosmetic preparations
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP18731075.0A
Other languages
German (de)
English (en)
Inventor
Sandra BRAREN
Heike Foelster
Julia GALLINGER
Stefan Gallinat
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beiersdorf AG
Original Assignee
Beiersdorf AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beiersdorf AG filed Critical Beiersdorf AG
Publication of EP3651858A1 publication Critical patent/EP3651858A1/fr
Withdrawn legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q15/00—Anti-perspirants or body deodorants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/36—Carboxylic acids; Salts or anhydrides thereof
    • A61K8/365—Hydroxycarboxylic acids; Ketocarboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof

Definitions

  • the present invention relates to the use of electrolytes in cosmetic preparations for the selective reduction of a microorganism population on the human skin.
  • the microorganism population comprises coryneous bacteria, and / or the dosage form of the cosmetic preparations relates to cosmetic deodorants.
  • apocrine sweat glands or scent glands release pheromone-like fragrances into the hair funnel, which are then converted together with the skin tallow and the action of skin bacteria into various odor substances bound to a hair follicle and confined to specific body regions.
  • Your secretion and that of the sebaceous glands as well as the respective bacterial flora of a skin region is responsible for the (natural) body odor, and can differentiate the smell of a body next to it by region.
  • Cosmetic deodorants serve to eliminate body odor, which arises when the per se odorless, especially apocrine fresh sweat is decomposed by microorganisms. An important role is played by the so-called coryneform bacteria.
  • the commercial cosmetic deodorants are based on different active principles.
  • antiperspirants can be reduced by astringents - predominantly aluminum salts such as aluminum hydroxychloride (Aluchlorhydrat) - the formation of sweat.
  • Aluchlorhydrat aluminum hydroxychloride
  • the substances used for this depending on their dosage, drastically interfere with the heat balance of the axillary region and should at best be used in exceptional cases.
  • the sweat flow itself is not affected, in the ideal case, only the microbial decomposition of the sweat is temporarily stopped.
  • body odor can also be masked by fragrances, a method that is least in line with the consumer's aesthetic needs, as the mixture of body odor and perfume smells rather unpleasant.
  • Plautus (244 - 184 BCE) in his "ghost story” ("Mostellaria", 1st lift, 3rd performance).
  • Deodorants should fulfill the following conditions:
  • liquid deodorants for example aerosol sprays, roll-ons and the like
  • solid preparations for example deodorant sticks ("sticks"), powders, powder sprays, intimate cleaners, etc.
  • the object of the present invention was thus to develop cosmetic deodorants which do not have the disadvantages of the prior art.
  • the deodorants should protect the microflora of the skin largely, but selectively reduce the number of microorganisms that are responsible for the body odor.
  • a further object was to develop cosmetic deodorants which harmonize with the widest possible variety of customary cosmetic auxiliaries and additives, in particular with the perfume ingredients which are especially important in deodorizing or antiperspirant formulations.
  • Yet another object of the invention was to provide cosmetic deodorants which are effective over a longer period of time, on the order of at least half a day, without noticeably reducing their effect.
  • mannitol-saline agar with a sodium chloride content of 7.5% is used in diagnostics and food analysis as a selective agar for staphylococci.
  • Non-odor-producing skin flora is, as described above, characterized by a low diversity, in particular a small amount of corynebacteria, peptostreptococci, anaerococci and Peponiphilus.
  • the ionic strength is influenced by electrolytes in the form of salts, but also by H 3 O + ions.
  • a particular embodiment of the present invention is based on a use which is characterized in that it comprises cosmetic preparations at least one aqueous phase in which or in which one or more electrolytes are dissolved, and wherein the ionic strength of the aqueous phase or phases, in which the electrolyte (s) dissolved is at least 0.050 mol / l.
  • the ionic strength / electrolyte solution is defined as where Ci represents the concentrations of the individual types of ions (in mol / l) and z, their charge numbers.
  • the physical unit of ionic strength is that of a concentration (mol / l).
  • ionic strengths which are greater than 0.075 mol / l, preferably greater than 0.1 mol / l, particularly preferably greater than 0.5 mol / l.
  • Another particular embodiment of the present invention is based on a use, which is characterized in that the one or more electrolytes are selected from the group
  • salts having the following anions chlorides, and also inorganic oxo element anions, of these in particular sulfates, carbonates, phosphates, borates and aluminates.
  • organic anion-based electrolytes are advantageous, e.g. Lactates, acetates, benzoates, propionates, tartrates, citrates, amino acids, ethylenediaminetetraacetic acid and their salts
  • Preferred electrolytes include the ammonium and alkali halides, especially saline.
  • Yet another particular embodiment of the present invention is due to a use characterized in that the microorganisms whose population is to be reduced are coryneform bacteria.
  • the cosmetic preparations are cosmetic deodorants whose effect is based on the fact that the microorganisms whose population is to be reduced to such organisms which decompose apocrine sweat.
  • a method of combating human body odor caused by microbial decomposition of apocrine sweat characterized in that an effective amount of one or more electrolytes or a cosmetic preparation comprising at least one aqueous phase in which or in which one or more Electrolytes dissolved are included, and wherein the ionic strength of the aqueous phase or phases in which the dissolved electrolyte (s) is at least 0.050 mol / l, is applied to the skin.
  • the invention also relates to the use of one or more electrolytes or a cosmetic preparation comprising at least one aqueous phase in which one or more electrolytes are dissolved, and wherein the ionic strength of the aqueous phase or phases in which the or the electrolytes are dissolved, at least 0.050 mol / l, to prevent the growth Grampositiver, especially Coryneformer bacteria.
  • the deodorants are particularly advantageously characterized in that the electrolyte (s) is present in concentrations of 0.5-30.00% by weight, preferably 1-25% by weight, particularly preferably 5-15% by weight. , in each case based on the total weight of the composition, is present or present.
  • the cosmetic deodorants may be present in the form of aerosols, ie aerosol containers, squeeze bottles or preparations which can be sprayed by a pump device or in the form of liquid compositions which can be applied by means of roll-on devices, as deodorant sticks (deodorant sticks) and in Form of W / O or O / W emulsions which can be applied from normal bottles and containers, eg Creams or lotions.
  • the cosmetic deodorants may advantageously be present in the form of deodorant tinctures, deodorizing intimate cleansing agents, deodorizing shampoos, deodorizing shower or bath preparations, deodorising powders or deodorising powder sprays.
  • customary cosmetic carriers for preparing the deodorizing preparations according to the invention
  • customary proportions are used as well as slime-forming substances and thickeners, for example hydroxyethyl or hydroxypropyl cellulose, polyacrylic acid, polyvinylpyrrolidone, but also in small amounts cyclic silicone oils (polydimethylsiloxanes) and liquid polymethylphenylsiloxanes low viscosity.
  • conventional antioxidants to the preparations for the purposes of the present invention. According to the invention, all antioxidants which are suitable or customary for cosmetic and / or dermatological applications can be used as favorable antioxidants.
  • the amount of antioxidants (one or more compounds) in the preparations is preferably from 0.001 to 30% by weight, particularly preferably from 0.05 to 20% by weight, in particular from 1 to 10% by weight, based on the total weight of the preparation ,
  • the cosmetic or dermatological preparation in the sense of the present invention is a solution or emulsion or dispersion, it is possible to use as solvent:
  • Oils such as triglycerides of capric or caprylic acid, but preferably castor oil;
  • Fats, waxes and other natural and synthetic fats preferably esters of fatty acids with lower C-number alcohols, e.g. with isopropanol, propylene glycol or glycerol, or esters of fatty alcohols with alkanoic acids of low C number or with fatty acids;
  • Alcohols, diols or polyols of low C number, and their ethers preferably ethanol, isopropanol, propylene glycol, glycerol, ethylene glycol, ethylene glycol monoethyl or monobutyl ether, propylene glycol monomethyl, monoethyl or monobutyl ether, diethylene glycol monomethyl or monoethyl ether and analogous products ,
  • mixtures of the abovementioned solvents are used.
  • alcoholic solvents water can be another ingredient.
  • the oil phase of the emulsions, oleogels or hydrodispersions or lipodispersions in the context of the present invention is advantageously selected from the group of esters of saturated and / or unsaturated, branched and / or unbranched alkanecarboxylic acids a chain length of 3 to 30 carbon atoms and saturated and / or unsaturated, branched and / or unbranched alcohols of a chain length of 3 to 30 carbon atoms, from the group consisting of esters of aromatic carboxylic acids and saturated and / or unsaturated, branched and / or unbranched alcohols having a chain length of 3 to 30 carbon atoms.
  • ester oils can then advantageously be selected from the group isopropyl myristate, isopropyl palmitate, isopropyl stearate, isopropyl oleate, n-butyl stearate, n-hexyl laurate, n-decyl oleate, isooctyl stearate, isononyl stearate, isononyl isononanoate, 2-ethylhexyl palmitate, 2-ethylhexyl laurate, 2-hexyldecyl stearate, 2 Octyl dodecyl palmitate, oleyl oleate, oleyl erucate, erucyl oleate, erucyl erucate and synthetic, semisynthetic and natural mixtures of such esters, eg. B. jojoba oil.
  • the oil phase can be advantageously selected from the group of branched and unbranched hydrocarbons and waxes, the silicone oils, the dialkyl ethers, the group of saturated or unsaturated, branched or unbranched alcohols, and the fatty acid triglycerides, namely the triglycerol esters of saturated and / or unsaturated, branched and / or unbranched alkanecarboxylic acids of a chain length of 8 to 24, in particular 1 2 - 18 C-atoms.
  • the fatty acid triglycerides can be advantageously selected from the group of synthetic, semi-synthetic and natural oils, e.g. Olive oil, sunflower oil, soybean oil, peanut oil, rapeseed oil, almond oil, palm oil, coconut oil, palm kernel oil, and the like.
  • any mixtures of such oil and wax components are also advantageous to use in the context of the present invention. It may also be advantageous, if appropriate, to use waxes, for example cetyl palmitate, as the sole lipid component of the oil phase.
  • the oil phase is advantageously selected from the group 2-ethylhexyl isostearate, octyldodecanol, isotridecyl isononanoate, isoeicosane, 2-ethylhexyl cocoate, C 2 -i 5-alkyl benzoate, caprylic-capric acid triglyceride, dicaprylyl ether.
  • Ci2-i5-alkyl benzoate and 2-ethylhexyl isostearate mixtures of Ci2-i5-alkyl benzoate and isotridecyl isononanoate and mixtures of C12-15- benzoate, 2-ethylhexyl isostearate and isotridecyl isononanoate.
  • hydrocarbons paraffin oil, squalane and squalene are to be used advantageously in the context of the present invention.
  • the oil phase may further comprise a content of cyclic or linear silicone oils or consist entirely of such oils, although it is preferred to use an additional content of other oil phase components in addition to the silicone oil or the silicone oils.
  • cyclomethicone octamethylcyclotetrasiloxane
  • silicone oils are also advantageous for the purposes of the present invention, for example hexamethylcyclotrisiloxane, polydimethylsiloxane, poly (methylphenylsiloxane).
  • mixtures of cyclomethicone and isotridecyl isononanoate, cyclomethicone and 2-ethylhexyl isostearate are particularly advantageous.
  • Gels used in the present invention usually contain low C number alcohols, e.g. Ethanol, isopropanol, 1, 2-propanediol, glycerol and water or an above-mentioned oil in the presence of a thickener which is preferably silica or an aluminum silicate in oily-alcoholic gels, preferably a polyacrylate in aqueous-alcoholic or alcoholic gels.
  • a thickener which is preferably silica or an aluminum silicate in oily-alcoholic gels, preferably a polyacrylate in aqueous-alcoholic or alcoholic gels.
  • the cosmetic or dermatological preparation in the sense of the present invention is a solution or emulsion or dispersion, it is possible to use as solvent:
  • Oils such as triglycerides of capric or caprylic acid, but preferably castor oil;
  • Fats, waxes and other natural and synthetic fats preferably esters of fatty acids with lower C-number alcohols, e.g. with isopropanol, propylene glycol or glycerol, or esters of fatty alcohols with alkanoic acids of low C number or with fatty acids;
  • Alcohols, diols or polyols of low C number, and their ethers preferably ethanol, isopropanol, propylene glycol, glycerol, ethylene glycol, ethylene glycol monoethyl or monobutyl ether, propylene glycol monomethyl, monoethyl or monobutyl ether, diethylene glycol monomethyl or monoethyl ether and analogous products ,
  • mixtures of the abovementioned solvents are used.
  • alcoholic solvents water can be another ingredient.
  • the oil phase of the emulsions, oleogels or hydrodispersions or lipodispersions in the context of the present invention is advantageously selected from the group of esters of saturated and / or unsaturated, branched and / or unbranched alkanecarboxylic acids having a chain length of 3 to 30 carbon atoms and saturated and / or or unsaturated, branched and / or unbranched alcohols having a chain length of 3 to 30 carbon atoms, from the group of esters of aromatic carboxylic acids and saturated and / or unsaturated, branched and / or unbranched alcohols having a chain length of 3 to 30 carbon atoms.
  • ester oils can then advantageously be selected from the group isopropyl myristate, isopropyl palmitate, isopropyl stearate, isopropyl oleate, n-butyl stearate, n-hexyl laurate, n-decyl oleate, isooctyl stearate, isononyl stearate, isononyl isononanoate, 2-ethylhexyl palmitate, 2-ethylhexyl laurate, 2-hexyldecyl stearate, 2 Octyl dodecyl palmitate, oleyl oleate, oleyl erucate, erucyl oleate, erucyl erucate and synthetic, semisynthetic and natural mixtures of such esters, eg. B. jojoba oil.
  • the oil phase can be advantageously selected from the group of branched and unbranched hydrocarbons and waxes, the silicone oils, the dialkyl ethers, the group of saturated or unsaturated, branched or unbranched alcohols, and the Fatty acid triglycerides, namely the triglycerol esters of saturated and / or unsaturated, branched and / or unbranched alkanecarboxylic acids having a chain length of 8 to 24, in particular 12-18, carbon atoms.
  • the fatty acid triglycerides can be selected, for example, advantageously from the group of synthetic, semi-synthetic and natural oils, for. For example, olive oil, sunflower oil, soybean oil, peanut oil, rapeseed oil, almond oil, palm oil, coconut oil, palm kernel oil and the like.
  • any mixtures of such oil and wax components are also advantageous to use in the context of the present invention. It may also be advantageous, if appropriate, to use waxes, for example cetyl palmitate, as the sole lipid component of the oil phase.
  • the oil phase is advantageously selected from the group 2-ethylhexyl isostearate, octyldodecanol, isotridecyl isononanoate, isoeicosane, 2-ethylhexyl cocoate, Ci2-i5-alkyl benzoate, caprylic-capric acid triglyceride, dicaprylyl ether.
  • Ci2-i5-alkyl benzoate and 2-ethylhexyl isostearate mixtures of Ci2-i5-alkyl benzoate and isotridecyl isononanoate and mixtures of C12-15- benzoate, 2-ethylhexyl isostearate and isotridecyl isononanoate.
  • hydrocarbons paraffin oil, squalane and squalene are to be used advantageously in the context of the present invention.
  • the oil phase may further comprise a content of cyclic or linear silicone oils or consist entirely of such oils, although it is preferred to use an additional content of other oil phase components in addition to the silicone oil or the silicone oils.
  • cyclomethicone (octamethylcyclotetrasiloxane) is used as the silicone oil to be used according to the invention.
  • other silicone oils are also advantageous for the purposes of the present invention, for example hexamethylcyclotrisiloxane, polydimethylsiloxane, poly (methylphenylsiloxane).
  • mixtures of cyclomethicone and isotridecyl isononanoate, of cyclomethicone and 2-ethylhexyl isostearate are particularly advantageous.
  • Gels used in the present invention usually contain low C number alcohols, e.g. Ethanol, isopropanol, 1, 2-propanediol, glycerol and water or an above-mentioned oil in the presence of a thickener which is preferably silica or an aluminosilicate in oily-alcoholic gels, in aqueous-alcoholic or alcoholic gels, preferably a polyacrylate.
  • a thickener which is preferably silica or an aluminosilicate in oily-alcoholic gels, in aqueous-alcoholic or alcoholic gels, preferably a polyacrylate.
  • Fixed pins contain z. As natural or synthetic waxes, fatty alcohols or fatty acid esters.
  • Typical base substances which are suitable for use as cosmetic sticks in the context of the present invention are liquid oils (for example paraffin oils, castor oil, isopropyl myristate), semi-solid constituents (eg petrolatum, lanolin), solid constituents ( eg beeswax, ceresin and microcrystalline waxes or ozokerite) and high-melting waxes (eg carnauba wax, candelilla wax).
  • liquid oils for example paraffin oils, castor oil, isopropyl myristate
  • semi-solid constituents eg petrolatum, lanolin
  • solid constituents eg beeswax, ceresin and microcrystalline waxes or ozokerite
  • high-melting waxes eg carnauba wax, candelilla wax
  • Suitable propellants for sprayable from aerosol containers cosmetic and / or dermatological preparations in the context of the present invention the usual known volatile, liquefied propellants, such as hydrocarbons (propane, butane, isobutane) are suitable, which can be used alone or in mixture with each other. Also, compressed air is advantageous to use.
  • hydrocarbons propane, butane, isobutane
  • Cosmetic preparations for the purposes of the present invention may also be present as gels which, in addition to an effective content of the active ingredient according to the invention and solvents customarily used for it, preferably water, also organic thickeners, eg gum arabic, xanthan gum, sodium alginate, cellulose derivatives, preferably methylcellulose, hydroxymethylcellulose, Hydroxyethylcellulose, hydroxypropylcellulose, hydroxypropylmethylcellulose or inorganic thickening agents, e.g. For example, aluminum silicates such as bentonites, or a mixture of polyethylene glycol and polyethylene glycol stearate or distearate.
  • the thickener is in the gel z. B. in an amount between 0.1 and 30 wt .-%, preferably between 0.5 and 15 wt .-%.
  • Preparations according to the present invention may also be distinguished by a content of surfactants.
  • Surfactants are amphiphilic substances that can dissolve organic, nonpolar substances in water. Due to their specific molecular structure with at least one hydrophilic and one hydrophobic part of the molecule, they provide for a lowering of the surface tension of the water, the wetting of the skin, the facilitation of dirt removal and dissolution, a gentle rinsing and, as desired, for foam regulation.
  • hydrophilic portions of a surfactant molecule are usually polar functional groups, such as -COO ⁇ , -OS0 3 2 ', -SOy representing while the hydrophobic parts radicals usually non-polar hydrocarbon.
  • surfactants are generally on the nature and charge of the classified into a hydrophilic part of the molecule, whereby four groups can be distinguished:
  • nonionic surfactants generally have carboxylate, sulfate or sulfonate groups as functional groups. In aqueous solution, they form negatively charged organic ions in an acidic or neutral medium. Cationic surfactants are almost exclusively characterized by the presence of a quaternary ammonium group. In aqueous solution they form positively charged organic ions in an acidic or neutral environment. Amphoteric surfactants contain both anionic and cationic groups and behave accordingly in aqueous solution depending on the pH as anionic or cationic surfactants. They have a positive charge in a strongly acidic environment and a negative charge in an alkaline environment. In the neutral pH range, however, they are zwitterionic, as the following example is intended to illustrate:
  • Non-ionic surfactants are polyether chains. Nonionic surfactants do not form ions in an aqueous medium.
  • Acylglutamates for example sodium acylglutamate, di-TEA-palmitoylaspartate and sodium caprylic / capric glutamate,
  • acyl peptides for example palmitoyl-hydrolyzed milk protein, sodium cocoyl-hydrolysed soy protein and sodium / potassium cocoyl-hydrolyzed collagen,
  • sarcosinates for example myristoyl sarcosine, TEA-lauroyl sarcosinate, sodium lauroyl sarcosinate and sodium cocoyl sarcosinate,
  • taurates for example sodium lauroyl taurate and sodium methyl cocoyl taurate
  • Carboxylic acids and derivatives such as 1 .
  • Carboxylic acids for example lauric acid, aluminum stearate, magnesium alkoxide and zinc undecylenate,
  • Ester carboxylic acids for example calcium stearoyl lactylate, laureth-6 citrate and sodium PEG-4 lauramide carboxylate,
  • Ether carboxylic acids for example sodium laureth-13 carboxylate and sodium PEG-6 cocamide carboxylate,
  • Phosphoric acid esters and salts such as DEA-oleth-10-phosphate and dilaureth-4-phosphate,
  • Sulfonic acids and salts such as
  • Alkyl sulfonates for example sodium coconut monoglyceride sulfate, sodium C 12-14 olefin sulfonate, sodium lauryl sulfoacetate and magnesium PEG-3 cocamide sulfate,
  • Sulfosuccinates for example dioctylsodium sulfosuccinate, disodium laurethsulfosuccinate, disodium laurylsulfosuccinate and disodium undecylenamido MEA sulfosuccinate, as well as
  • Sulfuric acid esters such as
  • Alkyl ether sulfate for example, sodium, ammonium, magnesium, MIPA, TIPA laureth sulfate, sodium myreth sulfate and sodium C12-13 pareth sulfate,
  • Alkyl sulfates for example sodium, ammonium and TEA lauryl sulfate.
  • Esterquats Quaternary surfactants contain at least one N atom covalently linked to 4 alkyl or aryl groups. This results in a positive charge regardless of the pH.
  • Advantageous are alkyl sulfobetaine, alkylamidopropyl sulfobetaine and alkyl amidopropyl hydroxysulfine.
  • the cationic surfactants used according to the invention can furthermore preferably be selected from the group of quaternary ammonium compounds, in particular benzyltrialkylammonium chlorides or bromides, such as, for example, benzyldimethylstearylammonium chloride, alkyltrialkylammonium salts, for example cetyltrimethylammonium chloride or bromide, alkyldimethylhydroxyethylammonium chlorides or bromides, dialkyldimethylammonium chlorides or bromides Alkylamidethyltrimethylammonium ether sulfates, alkylpyridinium salts, for example lauryl or cetylpyrimidinium chloride, imidazoline derivatives and compounds having a cationic character, such as amine oxides, for example alkyldimethylamine oxides or alkylaminoethyldimethylamine oxides. Cetyltrimethylammonium salts are particularly advantageous to use.
  • Acyl / dialkylethylenediamine for example sodium acylamphoacetate, disodium acyl amphodipropionate, disodium alkyl amphodiacetate, sodium acylamphohydroxypropyl sulphoneate, disodium acylamphodiacetate and sodium acylamphopropionate,
  • N-alkylamino acids for example aminopropylalkylglutamide, alkylaminopropionic acid, sodium alkylimidodipropionate and lauroamphocarboxyglycinate.
  • Alkanolamides such as Cocamide MEA / DEN MI PA
  • amine oxides such as cocoamidopropylamine oxide
  • Ethers for example ethoxylated / propoxylated alcohols, ethoxylated / propoxylated esters, ethoxylated / propoxylated glycerol esters, ethoxylated / propoxylated cholesterols, ethoxylated / propoxylated triglyceride esters, ethoxylated propoxylated lanolin, ethoxylated lated / propoxylated polysiloxanes, propoxylated POE ethers and alkyl polyglycosides such as lauryl glucoside, decyl glycoside and cocoglycoside.
  • Polyglycerol esters diglycerol esters, monoglycerol esters
  • Methyl glucose esters, esters of hydroxy acids en advantageous embodiments of the present invention.
  • Citric acid monohydrate 0.05 0.05 0.05 0.05
  • Steareth-21 0.5 0.5 0.5 0.5 0.5 0.5 0.5 0.5 0.5 0.5
  • Steareth-2 0.5 0.5 0.5 0.5 0.5 0.5 0.5 0.5 0.5 0.5
  • Citric acid monohydrate 0.05 0.05 0.05 0.05 0.05 0.05 0.05 0.05 0.05

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
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  • Chemical & Material Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Cosmetics (AREA)

Abstract

Utilisation d'électrolytes dans des préparations cosmétiques pour la réduction sélective d'une population de micro-organismes sur la peau humaine.
EP18731075.0A 2017-07-11 2018-06-12 Utilisation d'électrolytes dans des préparations cosmétiques pour la réduction sélective d'une population de micro-organismes sur la peau humaine Withdrawn EP3651858A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102017006534.9A DE102017006534A1 (de) 2017-07-11 2017-07-11 Verwendung von Elektrolyten in kosmetischen Zubereitungen zur selektiven Reduktion einer Mikroorganismenpopulation auf der menschlichen Haut
PCT/EP2018/065510 WO2019011553A1 (fr) 2017-07-11 2018-06-12 Utilisation d'électrolytes dans des préparations cosmétiques pour la réduction sélective d'une population de micro-organismes sur la peau humaine

Publications (1)

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EP3651858A1 true EP3651858A1 (fr) 2020-05-20

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EP18731075.0A Withdrawn EP3651858A1 (fr) 2017-07-11 2018-06-12 Utilisation d'électrolytes dans des préparations cosmétiques pour la réduction sélective d'une population de micro-organismes sur la peau humaine

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Country Link
EP (1) EP3651858A1 (fr)
DE (1) DE102017006534A1 (fr)
WO (1) WO2019011553A1 (fr)

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