EP3609809A1 - Dosing valve for a fluid product dispenser - Google Patents

Dosing valve for a fluid product dispenser

Info

Publication number
EP3609809A1
EP3609809A1 EP18724939.6A EP18724939A EP3609809A1 EP 3609809 A1 EP3609809 A1 EP 3609809A1 EP 18724939 A EP18724939 A EP 18724939A EP 3609809 A1 EP3609809 A1 EP 3609809A1
Authority
EP
European Patent Office
Prior art keywords
valve
pbt
metering
matrix
glass microspheres
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP18724939.6A
Other languages
German (de)
French (fr)
Other versions
EP3609809B1 (en
Inventor
Patrice LÉONÉ
Michael BAZIRE
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aptar France SAS
Original Assignee
Aptar France SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aptar France SAS filed Critical Aptar France SAS
Publication of EP3609809A1 publication Critical patent/EP3609809A1/en
Application granted granted Critical
Publication of EP3609809B1 publication Critical patent/EP3609809B1/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D83/00—Containers or packages with special means for dispensing contents
    • B65D83/14—Containers or packages with special means for dispensing contents for delivery of liquid or semi-liquid contents by internal gaseous pressure, i.e. aerosol containers comprising propellant for a product delivered by a propellant
    • B65D83/44—Valves specially adapted therefor; Regulating devices
    • B65D83/52—Valves specially adapted therefor; Regulating devices for metering
    • B65D83/54—Metering valves ; Metering valve assemblies

Definitions

  • the present invention relates to a metering valve for a fluid dispenser.
  • valve The preferred field of application of such a valve is the pharmaceutical, but this type of valve can also be used in other fields, for example cosmetics or perfumery.
  • the metering valves of the prior art comprise a valve body defining a metering chamber in which a valve slides between resting and operating positions.
  • the valve body and the valve are mostly made by molding plastics of the polymer type, such as polyethylene (PE), polypropylene (PP), polyacetal (POM) or polybutylene terephthalate (PBT).
  • PE polyethylene
  • PP polypropylene
  • POM polyacetal
  • PBT polybutylene terephthalate
  • the metering valves must meet the requirements of reduced tolerances and be of great dimensional stability for their very small components that constitute them. There is also a requirement of perfect cylindricity for these metering valve components, necessary to maintain the sealing points of the valve, despite a pressure of 5 bar that is found in the tank.
  • the injection-molding process is widely used for the production of parts for applications such as packaging, electricity, automotive, cosmetics or consumer goods. This process is also used in the advanced industry such as medical, pharmaceutical, aeronautic or nuclear.
  • the appearance of injected parts is a very important criterion, especially for medical applications for which a high level of quality is essential to guarantee patient safety.
  • some defects in appearance can be generated during the production of parts and their control in large-scale production can be difficult.
  • the presence of defects, especially on safety parts can cause malfunctions or fragility of devices such as metering valves.
  • defects can be remedied in several ways, for example by changing the parameters of the injection-molding process, by changing the design of the molding, or by adding additives to the polymers to improve their molding performance.
  • Nucleating agents are the most used additives, especially for eliminating surface defects. These nucleating agents act by modifying the kinetics of crystallization. These nucleating agents can be based on talc or organic products. Other products, such as blowing agents, may also be employed. They break down during the molding process to give a foamed structure. They can be based on sodium bicarbonate and sodium citrate.
  • the present invention aims to overcome the aforementioned problems.
  • the present invention also aims to provide such a metering valve for a reliable product distribution, regular and reproducible at each actuation of the dispenser.
  • the present invention also aims to provide a simple and inexpensive metering valve to manufacture and assemble.
  • the subject of the present invention is therefore a metering valve for a fluid dispenser, comprising a valve body defining a metering chamber in which a valve slides between positions. rest and actuation device, said valve body and / or said valve being made by injection molding of a material comprising a polybutylene terephthalate (PBT) matrix and glass microspheres dispersed in said PBT matrix.
  • PBT polybutylene terephthalate
  • said glass microspheres have a diameter of between 1 and 2000 ⁇ , advantageously between 1 and 100 ⁇ .
  • said glass microspheres are added to the PBT matrix at a level of between 1 and 20% by weight, advantageously between 1 and 15% by weight.
  • the present invention also relates to a fluid dispenser comprising a reservoir containing fluid to be dispensed, and a metering valve as described above.
  • said dispenser comprises an HFA gas as a propellant.
  • FIG. 1 is a schematic sectional view of a metering valve according to an advantageous embodiment
  • FIG. 2 is a graph comparing the Young's modulus of PBT alone and with various additives with that of PBT comprising microspheres according to the invention.
  • FIG. 3 is a graph comparing the coefficient of friction of PBT alone with that of PBT comprising microspheres according to the invention.
  • the metering valve shown in FIG. 1 is of the retention type. It is understood, however, that this is only an example, and that the present invention applies to all types of metering valves.
  • the valve comprises a valve body 10 extending along a longitudinal axis A. Within said valve body 10, a valve 30 slides between a rest position, which is that shown in Figure 1, and a dispensing position, in which the valve 30 is pressed inside the valve body 10.
  • This valve is intended to be assembled on a reservoir 1, preferably by means of a fastening element 5, which may be a crimp, screw or snap-on cap, and advantageously with the interposition of a neck seal 6.
  • a ring 4 can be assembled around the valve body, in particular to reduce the dead volume in the inverted position and to limit the contact of the fluid with the neck seal.
  • This ring may be of any shape, and the example of Figure 1 is not limiting.
  • the valve 30 is biased towards its rest position by a spring 8, which is arranged in the valve body 10 and which cooperates on the one hand with this valve body 10, and on the other hand with the valve 30, preferably with a radial collar 320 of the valve 30.
  • a metering chamber 20 is defined inside the valve body 10, said valve 30 sliding inside said metering chamber to allow the distribution of the contents thereof. when the valve is actuated.
  • the metering chamber is preferably defined between two annular seals, a valve seal 21 and a chamber seal 22, as is well known.
  • FIG. 1 shows the valve in the upright storage position, that is to say the position in which the metering chamber 20 is disposed above the tank 1.
  • the valve 30 has an outlet port 301 connected to an inlet port 302, which is disposed in the metering chamber 20 when the valve 30 is in the dispensing position.
  • the valve 30 can be made in two parts, namely an upper part 31 (also called high valve) and a lower part 32 (also called bottom valve).
  • the lower part 32 is in this embodiment assembled inside the high part 31.
  • An internal channel 33 is provided in the valve 30 which makes it possible to connect the metering chamber 20 to the reservoir 1, to fill said metering chamber 20 when, after each actuation of the valve, the valve 30 returns to its rest position under the The effect of the spring 8. This filling is done when the device is still in the inverted position of use, with the valve disposed below the tank.
  • said valve body and / or said valve is (are) produced by injection molding of a material comprising a polybutylene terephthalate (PBT) matrix and glass microspheres dispersed in said PBT matrix.
  • PBT polybutylene terephthalate
  • the solid glass microspheres are made from glass, advantageously recycled, and have the advantage of not containing free silica or heavy metals. They are in the form of powder. They have a basic pH, which is favorable when we want to limit the interactions with the active ingredients. They can be subjected to a coupling agent surface treatment, selected according to the nature of the matrix, and which allows a better adhesion between the microsphere and the matrix and a better dispersion.
  • microspheres of glasses typically have a diameter of between 1 and 2000 ⁇ .
  • glass microspheres with a diameter of between 3 and 100 ⁇ were used, with a median diameter of between 10 and 30 ⁇ .
  • These microspheres may be added to the PBT matrix at a level of between 1 and 20% by weight, advantageously between 1 and 15% by weight.
  • the microspheres make it possible to reduce the variability of crystallinity between the different batches of materials and thus of reduce problems during molding; this makes it possible to substantially reduce or even eliminate the problems of deformation of the components (called shrinkage) and to improve their dimensional stability;
  • the microspheres make it possible to increase the mechanical properties of the material in which they are dispersed; to characterize the mechanical strength of a material, tensile measurements are made, which makes it possible to obtain values of tensile stress or Young's modulus;
  • Figure 2 shows a significant improvement of the Young's modulus for PBT with glass microspheres, relative to PBT alone and with respect to PBT with various well-known additives, such as nucleating agent, talc or blowing agent;
  • Glass microspheres are of mineral origin, they do not bring additional extractables; on the contrary, they have a diluting effect; thus, with a 13% level of glass microsphere in a PBT matrix, a decrease of just over 15% in extractables was observed;
  • the microspheres make it possible to reduce the coefficient of friction;
  • the coefficient of friction is the ratio of the tensile force (response force allowing the device to move) to the force applied (normal force);
  • the dynamic coefficient and the static coefficient are two types of coefficient of friction: the dynamic coefficient and the static coefficient; the static coefficient is the coefficient measured at the beginning of the test; it is the force necessary to move the sample on the substrate and initiate the movement; we also speak of coefficient of adhesion; the dynamic coefficient is the coefficient necessary for the movement to be maintained at a constant speed; in our case, we used the values of the dynamic coefficient because the system is then stable and at constant speed; the test was to rub a steel ball on a defined material (here PBT, with and without microspheres) to determine a coefficient of friction; the results obtained reproduced in FIG.
  • microspheres make it possible to reduce the coefficient of friction; this allows to consider including a reduction of friction problems in the valves; the microspheres have no impact on the compatibility with the active principles; this has been tested by directly contacting PBT containing microspheres with active ingredients (for example formoterol fumarate), and by measuring by analytical techniques the degradation of these active principles; the tests carried out did not show impact of glass microspheres on this degradation.
  • active ingredients for example formoterol fumarate

Abstract

The invention relates to a dosing valve for a fluid product dispenser, comprising a valve body (10) defining a dispensing chamber (20) in which a valve (30) slides between idle and actuating positions, said valve body (10) and/or said valve (30) being made by injection moulding of a material comprising a polybutylene terephtalate (PBT) matrix and glass microspheres dispersed in said PBT matrix.

Description

Valve doseuse pour distributeur  Dispenser dosing valve
de produit fluide  Fluid product
La présente invention concerne une valve doseuse pour un distributeur de produit fluide. The present invention relates to a metering valve for a fluid dispenser.
Le domaine d'application privilégié d'une telle valve est la pharmaceutique, mais ce type de valve peut aussi être utilisé dans d'autres domaines, par exemple la cosmétique ou la parfumerie.  The preferred field of application of such a valve is the pharmaceutical, but this type of valve can also be used in other fields, for example cosmetics or perfumery.
Les valves doseuses de l'art antérieur comportent un corps de valve définissant une chambre de dosage dans laquelle coulisse une soupape entre des positions de repos et d'actionnement. Le corps de valve et la soupape sont la plupart du temps réalisés par moulage de matériaux plastiques du type polymère, tel que le polyéthylène (PE), le polypropylène (PP), le polyacetal (POM) ou le polybutylène téréphtalate (PBT). Or, les valves doseuses doivent répondre à des exigences de tolérances réduites et être d'une grande stabilité dimensionnelle pour leurs composants très petits qui les constituent. Il y a aussi une exigence de parfaite cylindricité pour ces composants de valves doseuses, nécessaire pour maintenir les points d'étanchéité de la valve, malgré une pression de 5 bars que l'on trouve dans le réservoir. Il y a également des exigences d'excellentes propriétés mécaniques pour les matériaux utilisés dans les composants qui constituent les valves doseuses, notamment en raison du fort niveau de contraintes mécanique qui peuvent survenir en particulier lors du remplissage du réservoir à travers ladite valve doseuse et/ou lors de l'utilisation de la valve doseuse par le patient. D'autres contraintes peuvent aussi affecter la fiabilité des valves doseuses, telles qu'un fonctionnement avec des différentiels de pression importants ou une abrasion liée à la présence de poudre.  The metering valves of the prior art comprise a valve body defining a metering chamber in which a valve slides between resting and operating positions. The valve body and the valve are mostly made by molding plastics of the polymer type, such as polyethylene (PE), polypropylene (PP), polyacetal (POM) or polybutylene terephthalate (PBT). However, the metering valves must meet the requirements of reduced tolerances and be of great dimensional stability for their very small components that constitute them. There is also a requirement of perfect cylindricity for these metering valve components, necessary to maintain the sealing points of the valve, despite a pressure of 5 bar that is found in the tank. There are also requirements for excellent mechanical properties for the materials used in the components that make up the metering valves, in particular because of the high level of mechanical stress that may arise in particular when filling the tank through said metering valve and / or when using the metering valve by the patient. Other constraints may also affect the reliability of the metering valves, such as operation with large pressure differentials or abrasion related to the presence of powder.
Le procédé d'injection-moulage est très largement utilisée pour la production de pièces destinées à des applications telles que l'emballage, l'électricité, l'automobile, la cosmétique ou les biens de consommation. Ce procédé est également employé dans l'industrie de pointe comme le médical, la pharmaceutique, l'aéronautique ou encore le nucléaire. L'aspect des pièces injectées est un critère très important, notamment pour les applications médicales pour lesquelles un niveau de qualité élevé est essentiel pour garantir la sécurité des patients. Ainsi, certains défauts d'aspect peuvent être générés lors de la fabrication des pièces et leur maîtrise en production à grande échelle peut s'avérer délicate. Or, la présence de défauts, notamment sur des pièces de sécurité, peut engendrer des dysfonctionnements ou une fragilité des dispositifs tels que les valves doseuses. Il existe différents types de défauts, en particulier les bavures, les toiles, les bulles d'air, les stries ou même des pièces incomplètes. The injection-molding process is widely used for the production of parts for applications such as packaging, electricity, automotive, cosmetics or consumer goods. This process is also used in the advanced industry such as medical, pharmaceutical, aeronautic or nuclear. The appearance of injected parts is a very important criterion, especially for medical applications for which a high level of quality is essential to guarantee patient safety. Thus, some defects in appearance can be generated during the production of parts and their control in large-scale production can be difficult. However, the presence of defects, especially on safety parts, can cause malfunctions or fragility of devices such as metering valves. There are different types of defects, especially burrs, canvases, air bubbles, streaks or even incomplete parts.
On peut remédier à ces défauts de plusieurs façons, par exemple par modifications des paramètres du procédé d'injection-moulage, par modifications du design de la pièce à mouler, ou par ajout d'additifs aux polymères pour améliorer leurs performances au moulage.  These defects can be remedied in several ways, for example by changing the parameters of the injection-molding process, by changing the design of the molding, or by adding additives to the polymers to improve their molding performance.
Les agents nucléants sont les additifs les plus utilisés, notamment pour éliminer les défauts de surface. Ces agents nucléants agissent en modifiant les cinétiques de cristallisation. Ces agents nucléants peuvent être à base talc ou de produits organiques. D'autres produits, tels que les agents gonflants, peuvent être également employés. Ils se décomposent lors du procédé de moulage pour donner une structure moussée. Ils peuvent être à base de bicarbonate de sodium et de citrate de sodium.  Nucleating agents are the most used additives, especially for eliminating surface defects. These nucleating agents act by modifying the kinetics of crystallization. These nucleating agents can be based on talc or organic products. Other products, such as blowing agents, may also be employed. They break down during the molding process to give a foamed structure. They can be based on sodium bicarbonate and sodium citrate.
Les documents FR3035382, WO2012072962, FR2767801 et DE2734950 décrivent des dispositifs de l'état de la technique.  The documents FR3035382, WO2012072962, FR2767801 and DE2734950 describe devices of the state of the art.
La présente invention a pour but de surmonter les problèmes susmentionnés.  The present invention aims to overcome the aforementioned problems.
La présente invention a encore pour but de fournir une telle valve doseuse permettant une distribution de produit fiable, régulière et reproductible à chaque actionnement du distributeur.  The present invention also aims to provide such a metering valve for a reliable product distribution, regular and reproducible at each actuation of the dispenser.
La présente invention a également pour but de fournir une valve doseuse simple et peu coûteuse à fabriquer et à assembler.  The present invention also aims to provide a simple and inexpensive metering valve to manufacture and assemble.
La présente invention a donc pour objet une valve doseuse pour distributeur de produit fluide, comprenant un corps de valve définissant une chambre de dosage dans laquelle coulisse une soupape entre des positions de repos et d'actionnement, ledit corps de valve et/ou ladite soupape étant réalisé(s) par moulage par injection d'un matériau comprenant une matrice de polybutylène téréphtalate (PBT) et des microsphères de verre dispersées dans ladite matrice PBT. The subject of the present invention is therefore a metering valve for a fluid dispenser, comprising a valve body defining a metering chamber in which a valve slides between positions. rest and actuation device, said valve body and / or said valve being made by injection molding of a material comprising a polybutylene terephthalate (PBT) matrix and glass microspheres dispersed in said PBT matrix.
Avantageusement, lesdites microsphères de verre ont un diamètre compris entre 1 et 2000 μιτι, avantageusement entre 1 et 100 μιτι.  Advantageously, said glass microspheres have a diameter of between 1 and 2000 μιτι, advantageously between 1 and 100 μιτι.
Avantageusement, lesdites microsphères de verre sont ajoutées à la matrice PBT à un taux compris entre 1 et 20 % en poids, avantageusement entre 1 et 15 % en poids.  Advantageously, said glass microspheres are added to the PBT matrix at a level of between 1 and 20% by weight, advantageously between 1 and 15% by weight.
La présente invention a aussi pour objet un distributeur de produit fluide, comprenant un réservoir contenant du produit fluide à distribuer, et une valve doseuse telle que décrite ci-dessus.  The present invention also relates to a fluid dispenser comprising a reservoir containing fluid to be dispensed, and a metering valve as described above.
Avantageusement, ledit distributeur comprend un gaz HFA en tant que gaz propulseur.  Advantageously, said dispenser comprises an HFA gas as a propellant.
Ces caractéristiques et avantages et d'autres apparaîtront plus clairement au cours de la description détaillée suivante, faite en référence aux dessins joints, donnés à titre d'exemples non limitatifs, et sur lesquels :  These and other features and advantages will appear more clearly in the following detailed description, with reference to the accompanying drawings, given as non-limiting examples, and in which:
La figure 1 est une vue schématique en coupe d'une valve doseuse selon un mode de réalisation avantageux,  FIG. 1 is a schematic sectional view of a metering valve according to an advantageous embodiment,
La figure 2 est un graphique comparant le Module de Young du PBT seul et avec différents additifs avec celui du PBT comportant des microsphères selon l'invention, et  FIG. 2 is a graph comparing the Young's modulus of PBT alone and with various additives with that of PBT comprising microspheres according to the invention, and
La figure 3 est un graphique comparant le coefficient de frottement du PBT seul avec celui du PBT comportant des microsphères selon l'invention.  FIG. 3 is a graph comparing the coefficient of friction of PBT alone with that of PBT comprising microspheres according to the invention.
Dans la description ci-après, les termes "haut", "bas", "supérieur" et inférieur" se réfèrent à la position droite représentée sur la figure 1 , et les termes "axial" et "radial" se réfèrent à l'axe longitudinal de la valve représenté sur la figure 1 .  In the description below, the terms "up", "down", "upper" and "lower" refer to the straight position shown in Fig. 1, and the terms "axial" and "radial" refer to the longitudinal axis of the valve shown in FIG.
La valve doseuse représentée sur la figure 1 est du type à rétention. Il est toutefois entendu que ceci n'est qu'un exemple, et que la présente invention s'applique à tous les types de valves doseuses. La valve comporte un corps de valve 10 s'étendant le long d'un axe longitudinal A. À l'intérieur dudit corps de valve 10, une soupape 30 coulisse entre une position de repos, qui est celle représentée sur la figure 1 , et une position de distribution, dans laquelle la soupape 30 est enfoncée à l'intérieur du corps de valve 10. The metering valve shown in FIG. 1 is of the retention type. It is understood, however, that this is only an example, and that the present invention applies to all types of metering valves. The valve comprises a valve body 10 extending along a longitudinal axis A. Within said valve body 10, a valve 30 slides between a rest position, which is that shown in Figure 1, and a dispensing position, in which the valve 30 is pressed inside the valve body 10.
Cette valve est destinée à être assemblée sur un réservoir 1 , de préférence au moyen d'un élément de fixation 5, qui peut être une capsule à sertir, à visser ou à encliqueter, et avantageusement avec interposition d'un joint de col 6. Éventuellement, une bague 4 peut être assemblée autour du corps de valve, notamment pour diminuer le volume mort en position inversée et pour limiter le contact du produit fluide avec le joint de col. Cette bague peut être de forme quelconque, et l'exemple de la figure 1 n'est pas limitatif.  This valve is intended to be assembled on a reservoir 1, preferably by means of a fastening element 5, which may be a crimp, screw or snap-on cap, and advantageously with the interposition of a neck seal 6. Optionally, a ring 4 can be assembled around the valve body, in particular to reduce the dead volume in the inverted position and to limit the contact of the fluid with the neck seal. This ring may be of any shape, and the example of Figure 1 is not limiting.
La soupape 30 est sollicitée vers sa position de repos par un ressort 8, qui est disposé dans le corps de valve 10 et qui coopère d'une part avec ce corps de valve 10, et d'autre part avec la soupape 30, de préférence avec une collerette radiale 320 de la soupape 30. Une chambre de dosage 20 est définie à l'intérieur du corps de valve 10, ladite soupape 30 coulissant à l'intérieur de ladite chambre de dosage pour permettre la distribution du contenu de celle-ci lorsque la valve est actionnée.  The valve 30 is biased towards its rest position by a spring 8, which is arranged in the valve body 10 and which cooperates on the one hand with this valve body 10, and on the other hand with the valve 30, preferably with a radial collar 320 of the valve 30. A metering chamber 20 is defined inside the valve body 10, said valve 30 sliding inside said metering chamber to allow the distribution of the contents thereof. when the valve is actuated.
La chambre de dosage est de préférence définie entre deux joints annulaires, un joint de soupape 21 et un joint de chambre 22, de manière bien connue.  The metering chamber is preferably defined between two annular seals, a valve seal 21 and a chamber seal 22, as is well known.
La figure 1 représente la valve en position droite de stockage, c'est-à- dire la position dans laquelle la chambre de dosage 20 est disposée au- dessus du réservoir 1 .  FIG. 1 shows the valve in the upright storage position, that is to say the position in which the metering chamber 20 is disposed above the tank 1.
La soupape 30 comporte un orifice de sortie 301 relié à un orifice d'entrée 302, qui est disposé dans la chambre de dosage 20 lorsque la soupape 30 est en position de distribution. La soupape 30 peut être réalisée en deux parties, à savoir une partie haute 31 (également appelée haut de soupape) et une partie basse 32 (également appelée bas de soupape). La partie basse 32 est dans ce mode de réalisation assemblée à l'intérieur de la partie haute 31 . Un canal interne 33 est prévu dans la soupape 30 qui permet de relier la chambre de dosage 20 au réservoir 1 , pour remplir ladite chambre de dosage 20 lorsque, après chaque actionnement de la valve, la soupape 30 revient vers sa position de repos sous l'effet du ressort 8. Ce remplissage se fait quand le dispositif est encore en position inversée d'utilisation, avec la valve disposée en-dessous du réservoir. The valve 30 has an outlet port 301 connected to an inlet port 302, which is disposed in the metering chamber 20 when the valve 30 is in the dispensing position. The valve 30 can be made in two parts, namely an upper part 31 (also called high valve) and a lower part 32 (also called bottom valve). The lower part 32 is in this embodiment assembled inside the high part 31. An internal channel 33 is provided in the valve 30 which makes it possible to connect the metering chamber 20 to the reservoir 1, to fill said metering chamber 20 when, after each actuation of the valve, the valve 30 returns to its rest position under the The effect of the spring 8. This filling is done when the device is still in the inverted position of use, with the valve disposed below the tank.
Selon l'invention ledit corps de valve et/ou ladite soupape est(sont) réalisé(s) par moulage par injection d'un matériau comprenant une matrice de polybutylène téréphtalate (PBT) et des microsphères de verre dispersées dans ladite matrice PBT.  According to the invention, said valve body and / or said valve is (are) produced by injection molding of a material comprising a polybutylene terephthalate (PBT) matrix and glass microspheres dispersed in said PBT matrix.
Alors que le moulage du PBT est problématique, avec une grande variabilité de la cristallinité d'un lot à l'autre, l'ajout de microsphères de verre dans une matrice PBT permet de maîtriser la cristallinité du matériau, et donc de diminuer les problèmes de moulage.  While the molding of PBT is problematic, with a great variability of the crystallinity from one batch to another, the addition of glass microspheres in a PBT matrix makes it possible to control the crystallinity of the material, and thus to reduce the problems molding.
Les microsphères de verre pleines sont réalisées à partir de verre, avantageusement recyclé, et présentent l'intérêt de ne pas contenir de silice libre ni de métaux lourds. Elles se présentent sous forme de poudre. Elles ont un pH basique, ce qui est favorable quand on veut limiter les interactions avec les principes actifs. Elles peuvent faire l'objet d'un traitement de surface avec agent de couplage, sélectionné en fonction de la nature de la matrice, et qui permet une meilleure adhésion entre la microsphère et la matrice ainsi qu'une meilleure dispersion.  The solid glass microspheres are made from glass, advantageously recycled, and have the advantage of not containing free silica or heavy metals. They are in the form of powder. They have a basic pH, which is favorable when we want to limit the interactions with the active ingredients. They can be subjected to a coupling agent surface treatment, selected according to the nature of the matrix, and which allows a better adhesion between the microsphere and the matrix and a better dispersion.
Les microsphères de verres ont typiquement un diamètre compris entre 1 et 2000 μιτι. Dans les divers tests réalisés et décrits ci-dessous, il a été utilisé des microsphères de verre de diamètre compris entre 3 et 100 μιτι, avec un diamètre médian compris entre 10 et 30 μιτι. Ces microsphères peuvent être ajoutées à la matrice PBT à un taux compris entre 1 et 20 % en poids, avantageusement entre 1 et 15 % en poids.  The microspheres of glasses typically have a diameter of between 1 and 2000 μιτι. In the various tests carried out and described below, glass microspheres with a diameter of between 3 and 100 μιτι were used, with a median diameter of between 10 and 30 μιτι. These microspheres may be added to the PBT matrix at a level of between 1 and 20% by weight, advantageously between 1 and 15% by weight.
L'ajout de microsphères de verre dans une matrice PBT permet d'obtenir notamment les améliorations suivantes:  The addition of glass microspheres in a PBT matrix makes it possible in particular to obtain the following improvements:
- lors du moulage, les microsphères permettent de diminuer la variabilité de cristallinité entre les différents lots de matières et ainsi de réduire les problèmes lors du moulage; cela permet notamment de sensiblement diminuer voire supprimer les problèmes de déformations des composants (appelées retassure) et d'améliorer leur stabilité dimensionnelle; during molding, the microspheres make it possible to reduce the variability of crystallinity between the different batches of materials and thus of reduce problems during molding; this makes it possible to substantially reduce or even eliminate the problems of deformation of the components (called shrinkage) and to improve their dimensional stability;
- les microsphères permettent d'augmenter les propriétés mécaniques du matériau dans lequel elles sont dispersées; pour caractériser la résistance mécanique d'un matériau, on réalise des mesures de traction, ce qui permet d'obtenir des valeurs de contrainte à la rupture ou module de Young; la figure 2 montre une amélioration significative du Module de Young pour le PBT avec les microsphères de verre, par rapport au PBT seul et par rapport au PBT avec différents additifs bien connus, tel qu'un agent nucléant, du talc ou un agent gonflant;  the microspheres make it possible to increase the mechanical properties of the material in which they are dispersed; to characterize the mechanical strength of a material, tensile measurements are made, which makes it possible to obtain values of tensile stress or Young's modulus; Figure 2 shows a significant improvement of the Young's modulus for PBT with glass microspheres, relative to PBT alone and with respect to PBT with various well-known additives, such as nucleating agent, talc or blowing agent;
- Les microsphères de verre sont d'origine minérale, elles n'apportent donc pas d'extractibles supplémentaires; elles ont au contraire un effet diluant; ainsi, avec un taux de 13% de microsphère de verre dans une matrice PBT, il a été observé une diminution d'un peu plus de 15% des extractibles;  - Glass microspheres are of mineral origin, they do not bring additional extractables; on the contrary, they have a diluting effect; thus, with a 13% level of glass microsphere in a PBT matrix, a decrease of just over 15% in extractables was observed;
- les microsphères permettent de diminuer le coefficient de frottement; le coefficient de frottement est le rapport de la force de traction (force de réponse permettant la mise en mouvement de l'appareil) sur la force appliquée (force normale); il existe deux types de coefficient de frottement : le coefficient dynamique et le coefficient statique; le coefficient statique est le coefficient mesuré en début de test; c'est la force nécessaire pour déplacer l'échantillon sur le substrat et initier le mouvement; on parle aussi de coefficient d'adhérence; le coefficient dynamique est le coefficient nécessaire pour que le mouvement soit maintenu à une vitesse constante; dans notre cas, nous avons utilisé les valeurs du coefficient dynamique car le système est alors stable et à vitesse constante; le test a consisté à faire frotter une bille d'acier sur un matériau défini (ici le PBT, avec et sans microsphères) afin de déterminer un coefficient de frottement; les résultats obtenus reproduits sur la figure 3 montrent que l'apport des microsphères permet de diminuer le coefficient de frottement; ceci permet d'envisager notamment une réduction des problèmes de frottement dans les valves; - les microsphères n'ont pas d'impact sur la compatibilité avec les principes actifs; ceci a été testé en mettant en contact direct du PBT contenant des microsphères avec des principes actifs (par exemple du fumarate de formoterol), et en mesurant par des techniques analytiques la dégradation de ces principes actifs; les essais réalisés n'ont pas montré d'impact des microsphères de verre sur cette dégradation. the microspheres make it possible to reduce the coefficient of friction; the coefficient of friction is the ratio of the tensile force (response force allowing the device to move) to the force applied (normal force); There are two types of coefficient of friction: the dynamic coefficient and the static coefficient; the static coefficient is the coefficient measured at the beginning of the test; it is the force necessary to move the sample on the substrate and initiate the movement; we also speak of coefficient of adhesion; the dynamic coefficient is the coefficient necessary for the movement to be maintained at a constant speed; in our case, we used the values of the dynamic coefficient because the system is then stable and at constant speed; the test was to rub a steel ball on a defined material (here PBT, with and without microspheres) to determine a coefficient of friction; the results obtained reproduced in FIG. 3 show that the contribution of the microspheres makes it possible to reduce the coefficient of friction; this allows to consider including a reduction of friction problems in the valves; the microspheres have no impact on the compatibility with the active principles; this has been tested by directly contacting PBT containing microspheres with active ingredients (for example formoterol fumarate), and by measuring by analytical techniques the degradation of these active principles; the tests carried out did not show impact of glass microspheres on this degradation.
La présente invention a été décrite en référence à un mode de réalisation avantageux, mais il est entendu qu'un homme du métier peut y apporter toutes modifications, sans sortir du cadre de la présente invention telle que défini par les revendications annexées.  The present invention has been described with reference to an advantageous embodiment, but it is understood that a person skilled in the art can make any modifications, without departing from the scope of the present invention as defined by the appended claims.

Claims

Revendications claims
1 . - Valve doseuse pour distributeur de produit fluide, comprenant un corps de valve (10) définissant une chambre de dosage (20) dans laquelle coulisse une soupape (30) entre des positions de repos et d'actionnement, caractérisé en ce que ledit corps de valve (10) et/ou ladite soupape (30) est(sont) réalisé(s) par moulage par injection d'un matériau comprenant une matrice de polybutylène téréphtalate (PBT) et des microsphères de verre dispersées dans ladite matrice PBT. 1. - Metering valve for fluid dispenser, comprising a valve body (10) defining a metering chamber (20) in which slides a valve (30) between resting and operating positions, characterized in that said body of valve (10) and / or said valve (30) is (are) made by injection molding a material comprising a polybutylene terephthalate (PBT) matrix and glass microspheres dispersed in said PBT matrix.
2. - Valve selon la revendication 1 , dans laquelle lesdites microsphères de verre ont un diamètre compris entre 1 et 2000 μιτι, avantageusement entre 1 et 100 μιτι. 2. - Valve according to claim 1, wherein said glass microspheres have a diameter between 1 and 2000 μιτι, preferably between 1 and 100 μιτι.
3. - Valve selon la revendication 1 ou 2, dans laquelle lesdites microsphères de verre sont ajoutées à la matrice PBT à un taux compris entre 1 et 20 % en poids, avantageusement entre 1 et 15 % en poids. 3. - Valve according to claim 1 or 2, wherein said glass microspheres are added to the PBT matrix at a level between 1 and 20% by weight, preferably between 1 and 15% by weight.
4. - Distributeur de produit fluide, comprenant un réservoir (1 ) contenant du produit fluide à distribuer, caractérisé en ce que ledit distributeur comporte une valve doseuse selon l'une quelconque des revendications précédentes. 4. - Fluid dispenser comprising a reservoir (1) containing fluid to be dispensed, characterized in that said dispenser comprises a metering valve according to any one of the preceding claims.
5. - Distributeur selon la revendication 5, comprenant un gaz HFA en tant que gaz propulseur. 5. - Dispenser according to claim 5, comprising a HFA gas as a propellant.
EP18724939.6A 2017-04-13 2018-04-09 Dosing valve for a fluid product dispenser Active EP3609809B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR1753244A FR3065176B1 (en) 2017-04-13 2017-04-13 DOSING VALVE FOR FLUID PRODUCT DISPENSER
PCT/FR2018/050884 WO2018189469A1 (en) 2017-04-13 2018-04-09 Dosing valve for a fluid product dispenser

Publications (2)

Publication Number Publication Date
EP3609809A1 true EP3609809A1 (en) 2020-02-19
EP3609809B1 EP3609809B1 (en) 2021-06-09

Family

ID=58993121

Family Applications (1)

Application Number Title Priority Date Filing Date
EP18724939.6A Active EP3609809B1 (en) 2017-04-13 2018-04-09 Dosing valve for a fluid product dispenser

Country Status (6)

Country Link
US (1) US20200047981A1 (en)
EP (1) EP3609809B1 (en)
JP (1) JP2020520859A (en)
CN (1) CN110650899A (en)
FR (1) FR3065176B1 (en)
WO (1) WO2018189469A1 (en)

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4111893A (en) * 1977-05-20 1978-09-05 Gaf Corporation Polybutylene terephthalate molding resin
US4157325A (en) * 1977-07-11 1979-06-05 Gaf Corporation PBT molding compositions
DE2734950A1 (en) * 1977-08-03 1979-02-15 Agrotop Graef & Habich Gmbh Dimensionally stable and wear-resistant nozzle - for spraying liq. agricultural soil additives, is made of glass-fibre- or glass-bead-reinforced polybutylene terephthalate!
JP3131949B2 (en) * 1991-10-11 2001-02-05 大日本インキ化学工業株式会社 Polyester resin composition
FR2670139B1 (en) * 1992-01-15 1993-12-24 Valois DOSING VALVE FOR USE IN THE REVERSE POSITION.
GB9626960D0 (en) * 1996-12-27 1997-02-12 Glaxo Group Ltd Valve for aerosol container
DE19835273A1 (en) * 1997-09-03 1999-03-04 Bespak Plc Metering valve for pressurized dispensing containers
JPH11166117A (en) * 1997-12-02 1999-06-22 Polyplastics Co Polybutylene terephthalate resin composition and molded product thereof
DE19924098A1 (en) * 1999-05-26 2000-12-07 Boehringer Ingelheim Pharma Stainless steel canister for propellant-powered MDIs
GB0315791D0 (en) * 2003-07-07 2003-08-13 3M Innovative Properties Co Two component molded valve stems
FR2852301B1 (en) * 2003-03-13 2006-02-10 Valois Sas DEVICE FOR DISPENSING FLUID PRODUCT
GB0315801D0 (en) * 2003-07-07 2003-08-13 3M Innovative Properties Co Multi-component valve stems
JP2005179631A (en) * 2003-11-28 2005-07-07 Aisin Seiki Co Ltd Composite material and production method therefor
US7503469B2 (en) * 2005-03-09 2009-03-17 Rexam Closure Systems Inc. Integrally molded dispensing valve and method of manufacture
EP2088354B1 (en) * 2008-02-08 2013-10-16 Greif International Holding BV. Valve for liquid containers
US8881944B2 (en) * 2008-06-30 2014-11-11 S.C. Johnson & Son, Inc. Overcap for and a method of actuating a volatile material dispenser
CH703028B1 (en) * 2010-04-28 2014-05-30 Coca Cola Co Push button dispenser for bottles with carbonated beverages.
FR2968283B1 (en) * 2010-12-03 2013-01-04 Valois Sas VALVE OF DISTRIBUTION OF FLUID PRODUCT.
FR2971772B1 (en) * 2011-02-17 2013-03-22 Valois Sas DEVICE FOR DISPENSING FLUID PRODUCT.
HUE031396T2 (en) * 2013-06-28 2017-07-28 Altachem Nv Valve member
CN103756298B (en) * 2013-12-03 2017-01-04 惠州市昌亿科技股份有限公司 A kind of thermoplastic polymer based thermal conductive composite and its preparation method and application
FR3035382B1 (en) * 2015-04-24 2019-10-18 Nemera La Verpilliere PERFECTLY VALVED DOSING VALVE FOR DISTRIBUTING AN AEROSOL COMPRISING A VALVE ROD
JP2018529587A (en) * 2015-08-04 2018-10-11 コスター テクノロジー スペシヤリ ソチエタ ペル アチオーニＣｏｓｔｅｒ Ｔｅｃｎｏｌｏｇｉｅ Ｓｐｅｃｉａｌｉ Ｓ．Ｐ．Ａ． Valve cups and containers for use in fluid media dispensing systems
CH712902A1 (en) * 2016-09-12 2018-03-15 Alpla Werke Alwin Lehner Gmbh & Co Kg Internal pressure resistant plastic container, in particular plastic aerosol container.
US20180169549A1 (en) * 2016-12-16 2018-06-21 Clarcor Engine Mobile Solutions, Llc Filter assembly with primer

Also Published As

Publication number Publication date
CN110650899A (en) 2020-01-03
FR3065176A1 (en) 2018-10-19
FR3065176B1 (en) 2019-06-07
US20200047981A1 (en) 2020-02-13
WO2018189469A1 (en) 2018-10-18
EP3609809B1 (en) 2021-06-09
JP2020520859A (en) 2020-07-16

Similar Documents

Publication Publication Date Title
EP2811951B1 (en) Device for packaging and dispensing a substance for ophthalmic use
EP1606194B1 (en) Distribution device for fluid product
EP0821775B1 (en) Inlet valve assembly
EP3609809B1 (en) Dosing valve for a fluid product dispenser
EP3981821A1 (en) Use of a material in cosmetic packaging and system for dispensing a pressurised product comprising at least one part consisting of or comprising said material
EP0385896B1 (en) Dispenser body, dispenser having such a body and cap therefor
EP1382536A1 (en) Device for the extemporaneous mixture of at least two products
EP1100624B1 (en) Fluid product dispensing device
EP1915921B1 (en) Fluid distributing system with reliable fitting of the plunger tube
EP3206968A1 (en) Device for dispensing a cosmetic product in aerosol form, associated assembly and method
WO2004013017A1 (en) Fluid product spraying device
FR3035382B1 (en) PERFECTLY VALVED DOSING VALVE FOR DISTRIBUTING AN AEROSOL COMPRISING A VALVE ROD
EP3199244A1 (en) Suction device for liquid product in a dispenser
EP3849921B1 (en) Valve seal and metering valve for fluid product dispenser
FR2966808A1 (en) FLUID PRODUCT DELIVERY SYSTEM AND BOTTLE
WO2019145613A1 (en) Fluid product dispensing device
EP3363544B2 (en) System for dispensing a fluid product
FR3035381A1 (en) AEROSOL DISPENSING VALVE COMPRISING A VALVE ROD
FR3038589B1 (en) PRESSURIZED PRODUCT DELIVERY DEVICE, DOSABLE DISPENSING VALVE AND METHOD FOR ASSEMBLING THE SAME.
WO2018203013A1 (en) Metering valve and fluid product dispensing device comprising such a valve
EP4255824A1 (en) Device for dispensing a fluid product, comprising a metering valve
FR3024521A1 (en) AEROSOL DISPENSING VALVE COMPRISING A SEAL

Legal Events

Date Code Title Description
STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: UNKNOWN

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE INTERNATIONAL PUBLICATION HAS BEEN MADE

PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: REQUEST FOR EXAMINATION WAS MADE

17P Request for examination filed

Effective date: 20191108

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

AX Request for extension of the european patent

Extension state: BA ME

DAV Request for validation of the european patent (deleted)
DAX Request for extension of the european patent (deleted)
GRAP Despatch of communication of intention to grant a patent

Free format text: ORIGINAL CODE: EPIDOSNIGR1

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: GRANT OF PATENT IS INTENDED

INTG Intention to grant announced

Effective date: 20201208

GRAS Grant fee paid

Free format text: ORIGINAL CODE: EPIDOSNIGR3

GRAA (expected) grant

Free format text: ORIGINAL CODE: 0009210

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE PATENT HAS BEEN GRANTED

AK Designated contracting states

Kind code of ref document: B1

Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

REG Reference to a national code

Ref country code: GB

Ref legal event code: FG4D

Free format text: NOT ENGLISH

REG Reference to a national code

Ref country code: CH

Ref legal event code: EP

Ref country code: AT

Ref legal event code: REF

Ref document number: 1400322

Country of ref document: AT

Kind code of ref document: T

Effective date: 20210615

REG Reference to a national code

Ref country code: DE

Ref legal event code: R096

Ref document number: 602018018408

Country of ref document: DE

REG Reference to a national code

Ref country code: IE

Ref legal event code: FG4D

Free format text: LANGUAGE OF EP DOCUMENT: FRENCH

REG Reference to a national code

Ref country code: LT

Ref legal event code: MG9D

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: FI

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20210609

Ref country code: HR

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20210609

Ref country code: LT

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20210609

Ref country code: BG

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20210909

REG Reference to a national code

Ref country code: AT

Ref legal event code: MK05

Ref document number: 1400322

Country of ref document: AT

Kind code of ref document: T

Effective date: 20210609

REG Reference to a national code

Ref country code: NL

Ref legal event code: MP

Effective date: 20210609

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: SE

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20210609

Ref country code: RS

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20210609

Ref country code: LV

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20210609

Ref country code: NO

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20210909

Ref country code: GR

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20210910

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: SK

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20210609

Ref country code: ES

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20210609

Ref country code: EE

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20210609

Ref country code: SM

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20210609

Ref country code: PT

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20211011

Ref country code: NL

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20210609

Ref country code: RO

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20210609

Ref country code: AT

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20210609

Ref country code: CZ

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20210609

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: PL

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20210609

REG Reference to a national code

Ref country code: DE

Ref legal event code: R097

Ref document number: 602018018408

Country of ref document: DE

PLBE No opposition filed within time limit

Free format text: ORIGINAL CODE: 0009261

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: NO OPPOSITION FILED WITHIN TIME LIMIT

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: DK

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20210609

26N No opposition filed

Effective date: 20220310

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: AL

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20210609

REG Reference to a national code

Ref country code: CH

Ref legal event code: PL

REG Reference to a national code

Ref country code: BE

Ref legal event code: MM

Effective date: 20220430

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: MC

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20210609

Ref country code: LU

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20220409

Ref country code: LI

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20220430

Ref country code: CH

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20220430

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: BE

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20220430

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: IE

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20220409

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: IT

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20220409

P01 Opt-out of the competence of the unified patent court (upc) registered

Effective date: 20230526

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: IT

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20220409

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: IT

Payment date: 20230411

Year of fee payment: 6

Ref country code: FR

Payment date: 20230427

Year of fee payment: 6

Ref country code: DE

Payment date: 20230412

Year of fee payment: 6

PGRI Patent reinstated in contracting state [announced from national office to epo]

Ref country code: IT

Effective date: 20220831

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: GB

Payment date: 20230424

Year of fee payment: 6

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: MK

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20210609

Ref country code: CY

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20210609