EP3608015A1 - Powder provision device for a powder metering apparatus - Google Patents

Powder provision device for a powder metering apparatus Download PDF

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Publication number
EP3608015A1
EP3608015A1 EP18187934.7A EP18187934A EP3608015A1 EP 3608015 A1 EP3608015 A1 EP 3608015A1 EP 18187934 A EP18187934 A EP 18187934A EP 3608015 A1 EP3608015 A1 EP 3608015A1
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EP
European Patent Office
Prior art keywords
powder
stirrer
rotation
supply device
container
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP18187934.7A
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German (de)
French (fr)
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EP3608015B1 (en
Inventor
Jonas Höpfer
Marco Weigel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Harro Hofliger Verpackungsmaschinen GmbH
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Harro Hofliger Verpackungsmaschinen GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Harro Hofliger Verpackungsmaschinen GmbH filed Critical Harro Hofliger Verpackungsmaschinen GmbH
Priority to EP18187934.7A priority Critical patent/EP3608015B1/en
Priority to CA3050484A priority patent/CA3050484A1/en
Priority to US16/534,784 priority patent/US11279502B2/en
Priority to CN201910729446.0A priority patent/CN110813157B/en
Publication of EP3608015A1 publication Critical patent/EP3608015A1/en
Application granted granted Critical
Publication of EP3608015B1 publication Critical patent/EP3608015B1/en
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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F23/00—Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
    • B01F23/60—Mixing solids with solids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F29/00—Mixers with rotating receptacles
    • B01F29/80—Mixers with rotating receptacles rotating about a substantially vertical axis
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B1/00—Packaging fluent solid material, e.g. powders, granular or loose fibrous material, loose masses of small articles, in individual containers or receptacles, e.g. bags, sacks, boxes, cartons, cans, or jars
    • B65B1/30—Devices or methods for controlling or determining the quantity or quality or the material fed or filled
    • B65B1/36—Devices or methods for controlling or determining the quantity or quality or the material fed or filled by volumetric devices or methods
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F29/00—Mixers with rotating receptacles
    • B01F29/80—Mixers with rotating receptacles rotating about a substantially vertical axis
    • B01F29/83—Mixers with rotating receptacles rotating about a substantially vertical axis with rotary paddles or arms, e.g. movable out of the receptacle
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/71—Feed mechanisms
    • B01F35/717—Feed mechanisms characterised by the means for feeding the components to the mixer
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/80—Forming a predetermined ratio of the substances to be mixed
    • B01F35/83—Forming a predetermined ratio of the substances to be mixed by controlling the ratio of two or more flows, e.g. using flow sensing or flow controlling devices
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/80—Forming a predetermined ratio of the substances to be mixed
    • B01F35/88—Forming a predetermined ratio of the substances to be mixed by feeding the materials batchwise
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B1/00—Packaging fluent solid material, e.g. powders, granular or loose fibrous material, loose masses of small articles, in individual containers or receptacles, e.g. bags, sacks, boxes, cartons, cans, or jars
    • B65B1/04—Methods of, or means for, filling the material into the containers or receptacles
    • B65B1/10—Methods of, or means for, filling the material into the containers or receptacles by rotary feeders
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B35/00—Supplying, feeding, arranging or orientating articles to be packaged
    • B65B35/30—Arranging and feeding articles in groups
    • B65B35/34—Arranging and feeding articles in groups by agitators or vibrators

Definitions

  • the invention relates to a powder supply device for a powder dispenser with the features according to the preamble of claim 1.
  • the quantity of powder to be dosed is delimited by inserting a sleeve into a powder bed which is kept ready in a powder container.
  • the defined amount of powder is compacted in the sleeve by means of a stamp.
  • the sleeve with the limited amount of powder contained therein is then pulled out of the powder bed.
  • the powder container, together with the powder bed it contains, is now rotated relative to the fixedly positioned dosing device so that the plunger sleeve of the dosing device can dip into a fresh area of the powder bed.
  • the setting of the rakes and guide plates is carried out manually. Their effect is hardly reproducible, sensitive to changes of all kinds and also speed-dependent.
  • the invention is based on the object of developing a generic powder preparation device in such a way that a powder bed can be provided in a more uniform and reproducible state.
  • a powder preparation device for a powder metering device, the stationary smoothing device of which comprises a stirrer with at least one stirrer which projects into the interior of the powder container and can be driven in rotation.
  • the stirrer reliably levels puncture craters in the powder bed without adversely affecting the powder properties such as powder density or the like.
  • the stirring rotary movement of the stirrer means that its effect is homogeneous within a certain width. There are no locally deepened furrows in the wake of the stirrer. Rather, the stationary but rotatably mounted and driven stirrer produces a wide and uniform wake in the powder bed moved relative to it, within which the plunger or siphons find reproducible dosing conditions.
  • the at least one stirrer may be immersed in the interior of the powder container or in the powder bed with the axis of rotation lying obliquely to the vertical. However, it preferably has a vertically oriented axis of rotation. This ensures that the stirring effect has no significant vertical or axial components. This contributes to the further homogenization of the powder surface or the powder height level while avoiding local elevations or depressions.
  • the agitator has two oppositely drivable and intermeshing agitators.
  • a symmetrically designed agitating effect is produced with a further improved uniformity.
  • the stirrer expediently has at least one axial mixing element and / or one radial mixing element.
  • An axial mixing element here means a mixing element which extends at least partially in the direction of the axis of rotation of the stirrer.
  • a radial mixing element here means a mixing element which extends at least in part in the radial direction relative to the axis of rotation of the stirrer. It does not have to be an exact axial or radial alignment. Rather, such embodiments are also included which run obliquely to the respective directions and only partially have a directional component with respect to the named directions. In any case, this ensures that the mixing effect occurs within a target volume of the powder bed with pronounced uniformity.
  • the rotary movement of the stirrer is coupled to the rotary movement of the powder container.
  • the run of the stirrer is therefore synchronized with the run of the powder container.
  • the effect of the stirrer is therefore independent of the operating speed. In particular, this also allows a clocked one Operation with acceleration and deceleration phases in which the powder bed preparation is always carried out uniformly despite varying speeds.
  • the overall result is that the powder bed is prepared with significantly improved reproducibility and uniformity. Adjustments are practically not necessary.
  • the dosing accuracy of the powder removed from the powder supply device according to the invention is significantly increased.
  • Fig. 1 shows a schematic plan view of a section of a system which comprises a powder metering device 1 and a powder supply device 4 for the powder metering device 1.
  • Part of the powder supply device 4 according to the invention is a powder container 5, in which a powder bed 3 made of a powdery product is kept ready.
  • the powdery product here is a pharmaceutical preparation.
  • other powdery products are also suitable for forming the powder bed 3 and for processing by means of the powder supply device 4. Partial quantities of the powdery product are removed from the powder bed 3 by means of the powder dosing device 1 and each delimited as a defined dosing amount.
  • the powder metering device 1 is an only schematically indicated piercing station with four piercing levers 2, for example, the cylindrical ones of which are indicated Sleeves from above, i.e. perpendicular to the plane of the drawing Fig. 1 Immerse in the powder bed 3 in order to delimit, compact there in a known manner and to remove it for further processing, in particular for transfer into target containers (not shown).
  • a piercing station other types of powder metering device 1 can also be used.
  • the powder supply device 4 comprises, in addition to the pot-shaped powder container 5 mentioned, a smoothing device 6 for the powder bed 3, the further details of which can be found in the overview of Fig. 1 With Fig. 2 result.
  • Fig. 2 shows the powder supply device in a sectional view Fig. 1 in a section plane perpendicular to the plane of the drawing Fig. 1 .
  • the smoothing device 6 like the powder metering device 1, is mounted in a stationary manner, while the powder container 5 is mounted such that it can rotate about a vertical axis of rotation 12 and during operation about this axis of rotation according to an arrow 13 ( Fig. 1 ) is driven in rotation.
  • the powder bed 3 in the powder container 5 follows this rotary movement, so that it exerts a relative movement with respect to the fixedly positioned powder metering device 1 and also with respect to the firmly positioned smoothing device 6.
  • the mentioned rotary movement of powder container 5 and powder bed 3 about the axis of rotation 12 is intermittent or clocked.
  • the rotary movement is stopped.
  • the rotary movement of the powder container 5 and powder bed 3 unit is then started and stopped again after a defined angular step has been carried out, after which the dimensioning or dosing process begins again.
  • the powder bed 3 demonstrates as shown Fig. 2 a surface 19 in which the plunger 2 ( Fig. 1 ) leave craters after pulling out.
  • the execution of the said angular step helps to ensure that the powder dispenser 1 finds a powder bed 3 with the most homogeneous properties possible and the most undisturbed surface 19 with each dimensioning or dosing process.
  • the above-mentioned smoothing device 6 for the powder bed 3 is positioned behind the powder metering device 1 in the direction of rotation (arrow 13).
  • the smoothing device 6 comprises an agitator 7, which in turn comprises at least one, here two agitators 8, 9.
  • the two stirrers 8, 9 have drive shafts, by means of which they are rotatably mounted in a fixed bearing plate 18 which does not rotate with the powder container.
  • One stirrer 8 has a vertical axis of rotation 14 and the other stirrer 9 has a vertical axis of rotation 16. Both axes of rotation 14, 16 of the stirrers 8, 9 are axially parallel to one another and also axially parallel to the axis of rotation 12 of the powder container 5.
  • Both stirrers 8, 9 each have at least one, here four axial mixing elements 10 and optionally also at least one, here four radial mixing elements 11 each made of bent wire.
  • the axial mixing elements 10 run parallel to the respective axis of rotation 14, 16, but can also lie at an oblique angle thereto and, for example, run helically.
  • the radial mixing elements run radially with respect to the respective axis of rotation 14, 16. It also applies to them that they do not have to have exactly this course, but also lie at an oblique angle thereto and can for example run spirally.
  • the stirrers 8, 9 are positioned such that their axial and radial mixing elements 10, 11 protrude into the interior of the powder container 5 and there into the powder bed 3.
  • the immersion depth of the stirrers 8, 9 below the surface 19 of the powder bed 3 practically extends to the bottom of the powder container 5. In any case, it is preferably at least as great as the immersion depth of the piercing lifter 2.
  • both stirrers 8, 9 lie in the same direction of rotation of the powder container 5 in the same relative position as the powder metering device 1, however are spaced apart in the radial direction. However, it may also be expedient to position the two stirrers 8, 9 in the direction of rotation of the powder container 5.
  • both stirrers 8, 9 are driven in opposite directions about their respective axes of rotation 14, 16 during operation, as is indicated by arrows 15, 17. The distance between the two axes of rotation 14, 16 is smaller than the diameter of the stirrers 8, 9, as a result of which the mixing elements 10, 11 of both stirrers 8, 9 mesh with one another.
  • a suitable rotation angle offset prevents a collision of the mixing elements 8, 9 with one another.
  • both stirrers 8, 9 produce a gap-free effective width, which extends radially to the axis of rotation 12 of the powder container 5 to such an extent that the effective width of the powder metering device 1, or all of its piercing levers 2, which is also measured radially to the axis of rotation 12 of the powder container 5, is completely covered.
  • the wake of the entire powder dosing device 1 occurring in the powder bed 3 is completely captured by the mixing elements 8, 9.
  • the rotary movement of the two stirrers 8, 9 is coupled to the rotary movement of the powder container 5. This can be brought about, for example, by a common drive and a mechanical positive coupling by means of gear wheels, but also by a suitable electronic control in the case of separate drives.
  • the stirrers 8, 9 stand still when the powder container 5 stands still. And they rotate when the powder container 5 also rotates. In the acceleration and deceleration phases of the powder container 5, the stirrers 8, 9 also perform correspondingly accelerated or decelerated rotary movements.

Abstract

Die Erfindung betrifft eine Pulverbereitstellungseinrichtung (4) für einen Pulverdosierer (1), insbesondere für eine Stechheberstation. Die Pulverbereitstellungseinrichtung (4) umfasst einen drehend antreibbaren Pulverbehälter (5) zur Aufnahme eines Pulverbetts (3) und eine ortsfest gelagerte Glättungseinrichtung (6) für das Pulverbett (3). Die ortsfest gelagerte Glättungseinrichtung (6) umfasst ein Rührwerk (7) mit mindestens einem in den Innenraum des Pulverbehälters (5) ragenden, drehend antreibbaren Rührer (8, 9).The invention relates to a powder supply device (4) for a powder metering device (1), in particular for a piercing station. The powder supply device (4) comprises a powder container (5) which can be driven in rotation to receive a powder bed (3) and a stationary smoothing device (6) for the powder bed (3). The stationary smoothing device (6) comprises a stirrer (7) with at least one stirrer (8, 9) which can be driven in rotation and projects into the interior of the powder container (5).

Description

Die Erfindung betrifft eine Pulverbereitstellungseinrichtung für einen Pulverdosierer mit den Merkmalen nach dem Oberbegriff des Anspruchs 1.The invention relates to a powder supply device for a powder dispenser with the features according to the preamble of claim 1.

Bei der Dosierung von Pulvern insbesondere mittels sogenannter Stechheber erfolgt die Abgrenzung der zu dosierenden Pulvermenge durch das Einstechen einer Hülse in ein Pulverbett, welches in einem Pulverbehälter bereitgehalten wird. Die abgegrenzte Pulvermenge wird mittels eines Stempels in der Hülse kompaktiert. Die Hülse mit der darin enthaltenen abgegrenzten Pulvermenge wird dann aus dem Pulverbett herausgezogen. Der Pulverbehälter wird nun zusammen mit seinem darin enthaltenen Pulverbett relativ zum ortsfest positionierten Dosierer gedreht, damit die Stechheberhülse des Dosierers in einen frischen Bereich des Pulverbettes eintauchen kann.When dosing powders, in particular by means of a so-called stick lifter, the quantity of powder to be dosed is delimited by inserting a sleeve into a powder bed which is kept ready in a powder container. The defined amount of powder is compacted in the sleeve by means of a stamp. The sleeve with the limited amount of powder contained therein is then pulled out of the powder bed. The powder container, together with the powder bed it contains, is now rotated relative to the fixedly positioned dosing device so that the plunger sleeve of the dosing device can dip into a fresh area of the powder bed.

Der vorstehend umrissene Vorgang hinterlässt Einstichkrater im Pulverbett, die beim Weiterdrehen des Pulverbehälters wieder geschlossen werden müssen. Viele Pulversorten sind jedoch so beschaffen, dass sich die Krater nicht in jedem Fall von alleine schließen. Zur Unterstützung des Schließvorganges wird deshalb eine ortsfest gelagerte Glättungseinrichtung eingesetzt, die im Stand der Technik Rechen und Leitbleche umfasst. In Folge der Relativbewegung des sich mit dem Pulverbehälter mitdrehenden Pulverbetts gegenüber den ortsfesten Rechen und Leitblechen sollen sich die Krater schließen.The process outlined above leaves puncture craters in the powder bed, which must be closed again when the powder container is turned further. However, many types of powder are designed in such a way that the craters do not always close on their own. To support the closing process, therefore, a stationary smoothing device is used, which includes rakes and baffles in the prior art. As a result of the relative movement of the powder bed rotating with the powder container relative to the fixed rakes and baffles, the craters should close.

Die genannten Bauteile, namentlich die Rechen und Leitbleche, welche passiv im Pulverbett hängen, haben jedoch den Nachteil, dass sie in Bewegungsrichtung hinter sich einen Nachlauf erzeugen, also quasi einen "Schatten" werfen, der eine furchenförmige Vertiefung im Pulverbett bildet und zudem die Dichte des Pulvers lokal verändert. Sofern nun eine Hülse in eine solche Furche sticht, ist deren Füllmenge gegenüber denjenigen Hülsen reduziert, welche in einen Pulverbettbereich ohne Furche eintauchen. Es kommt noch hinzu, dass im Stand der Technik die Einstellung der Rechen und Leitbleche manuell erfolgt. Ihre Wirkung ist kaum reproduzierbar, sensibel gegen Änderungen aller Art und außerdem geschwindigkeitsabhängig.The components mentioned, namely the rakes and guide plates, which hang passively in the powder bed, have the disadvantage, however, that they create a wake behind them in the direction of movement, that is to say cast a "shadow" that forms a furrow-shaped depression in the powder bed and also the density of the powder changed locally. If a sleeve now sticks into such a furrow, its filling quantity is reduced compared to those sleeves which plunge into a powder bed area without a furrow. In addition, in the prior art, the setting of the rakes and guide plates is carried out manually. Their effect is hardly reproducible, sensitive to changes of all kinds and also speed-dependent.

Der Erfindung liegt nun die Aufgabe zu Grunde, eine gattungsbildende Pulverbereitstellungseinrichtung derart weiterzubilden, dass damit ein Pulverbett in einem gleichmäßigeren und besser reproduzierbaren Zustand bereitgestellt werden kann.The invention is based on the object of developing a generic powder preparation device in such a way that a powder bed can be provided in a more uniform and reproducible state.

Nach der Erfindung ist eine Pulverbereitstellungseinrichtung für einen Pulverdosierer vorgesehen, deren ortsfest gelagerte Glättungseinrichtung ein Rührwerk mit mindestens einem in den Innenraum des Pulverbehälters ragenden, drehend antreibbaren Rührer umfasst. Der Rührer bewirkt eine zuverlässige Einebnung von Einstichkratern im Pulverbett, ohne die Pulvereigenschaften wie Pulverdichte oder dergleichen nachteilig zu beeinflussen. Anders als bei einem passiven, also unbewegten Element führt die rührende Drehbewegung des Rührers dazu, dass seine Wirkung innerhalb einer bestimmten Breite homogen ist. Im Nachlauf der Rührers entstehen keine lokal vertieften Furchen. Vielmehr erzeugt der ortsfest, aber drehbar gelagerte und angetriebene Rührer im relativ dazu bewegten Pulverbett einen breiten und gleichförmigen Nachlauf, innerhalb dessen der oder die Stechheber reproduzierbare Dosierbedingungen vorfinden.According to the invention, a powder preparation device is provided for a powder metering device, the stationary smoothing device of which comprises a stirrer with at least one stirrer which projects into the interior of the powder container and can be driven in rotation. The stirrer reliably levels puncture craters in the powder bed without adversely affecting the powder properties such as powder density or the like. Unlike a passive, i.e. unmoving element, the stirring rotary movement of the stirrer means that its effect is homogeneous within a certain width. There are no locally deepened furrows in the wake of the stirrer. Rather, the stationary but rotatably mounted and driven stirrer produces a wide and uniform wake in the powder bed moved relative to it, within which the plunger or siphons find reproducible dosing conditions.

Es kann zweckmäßig sein, dass der mindestens eine Rührer mit schräg zur Vertikalen liegender Drehachse in den Innenraum des Pulverbehälters bzw. in das Pulverbett eintaucht. Bevorzugt weist er jedoch eine vertikal ausgerichtete Drehachse auf. Hierdurch wird erreicht, dass die Rührwirkung keine wesentlichen Vertikal- bzw. Axialkomponenten aufweist. Dies trägt zur weiteren Vergleichmäßigung der Pulveroberfläche bzw. des Pulverhöhenniveaus unter Vermeidung von lokalen Erhöhungen bzw. Vertiefungen bei.It may be expedient for the at least one stirrer to be immersed in the interior of the powder container or in the powder bed with the axis of rotation lying obliquely to the vertical. However, it preferably has a vertically oriented axis of rotation. This ensures that the stirring effect has no significant vertical or axial components. This contributes to the further homogenization of the powder surface or the powder height level while avoiding local elevations or depressions.

In bevorzugter Weiterbildung der Erfindung weist das Rührwerk zwei gegenläufig antreibbare und ineinander greifende Rührer auf. Bezüglich der relativen Drehbewegung des Pulverbehälters zusammen mit dem Pulverbett gegenüber dem Rührwerk entsteht eine symmetrisch ausgebildete Rührwirkung mit weiter verbesserter Gleichförmigkeit.In a preferred development of the invention, the agitator has two oppositely drivable and intermeshing agitators. With regard to the relative rotational movement of the powder container together with the powder bed relative to the agitator, a symmetrically designed agitating effect is produced with a further improved uniformity.

Der Rührer weist zweckmäßig mindestens ein axiales Mischelement und/oder ein radiales Mischelement auf. Als axiales Mischelement ist hier ein Mischelement gemeint, welches sich zumindest anteilig in Richtung der Drehachse des Rührers erstreckt. Als radiales Mischelement ist hier ein Mischelement gemeint, welches sich zumindest anteilig in radialer Richtung relativ zur Drehachse des Rührers erstreckt. Dabei muss es sich nicht um eine exakt axiale oder radiale Ausrichtung handeln. Vielmehr sind auch solche Ausführungsformen mit umfasst, die schräg zu den jeweiligen Richtungen verlaufen und dabei nur anteilig eine Richtungskomponente bezüglich der genannten Richtungen aufweisen. Jedenfalls wird dadurch sichergestellt, dass die Durchmischungswirkung innerhalb eines Zielvolumens des Pulverbetts mit ausgeprägter Gleichmäßigkeit eintrifft.The stirrer expediently has at least one axial mixing element and / or one radial mixing element. An axial mixing element here means a mixing element which extends at least partially in the direction of the axis of rotation of the stirrer. A radial mixing element here means a mixing element which extends at least in part in the radial direction relative to the axis of rotation of the stirrer. It does not have to be an exact axial or radial alignment. Rather, such embodiments are also included which run obliquely to the respective directions and only partially have a directional component with respect to the named directions. In any case, this ensures that the mixing effect occurs within a target volume of the powder bed with pronounced uniformity.

In einer vorteilhaften Ausführungsform ist die Drehbewegung des Rührers an die Drehbewegung des Pulverbehälters gekoppelt. Der Lauf des Rührers ist also mit dem Lauf des Pulverbehälters synchronisiert. Die Wirkung des Rührers ist folglich unabhängig von der Betriebsgeschwindigkeit. Dies erlaubt insbesondere auch einen getakteten Betrieb mit Beschleunigungs- und Verzögerungsphasen, in denen die Pulverbettaufbereitung trotz variierender Geschwindigkeiten immer gleichmäßig erfolgt.In an advantageous embodiment, the rotary movement of the stirrer is coupled to the rotary movement of the powder container. The run of the stirrer is therefore synchronized with the run of the powder container. The effect of the stirrer is therefore independent of the operating speed. In particular, this also allows a clocked one Operation with acceleration and deceleration phases in which the powder bed preparation is always carried out uniformly despite varying speeds.

Insgesamt ist erreicht, dass die Pulverbettaufbereitung mit erheblich verbesserter Reproduzierbarkeit und Gleichmäßigkeit erfolgt. Einstellarbeiten sind praktisch nicht erforderlich. Die Dosiergenauigkeit des aus der erfindungsgemäßen Pulverbereitstellungseinrichtung entnommenen Pulvers ist deutlich gesteigert.The overall result is that the powder bed is prepared with significantly improved reproducibility and uniformity. Adjustments are practically not necessary. The dosing accuracy of the powder removed from the powder supply device according to the invention is significantly increased.

Ein Ausführungsbeispiel der Erfindung ist nachfolgend anhand der Zeichnung näher erläutert. Es zeigen:

Fig. 1
in einer schematischen Draufsicht ein System aus einem Pulverdosierer und einer erfindungsgemäßen Pulverbereitstellungseinrichtung mit zwei gegenläufig angetriebenen Rührern, und
Fig. 2
in einer Schnittdarstellung die Pulverbereitstellungseinrichtung nach Fig. 1 mit Einzelheiten seiner als Rührwerk ausgebildeten Glättungseinrichtung.
An embodiment of the invention is explained below with reference to the drawing. Show it:
Fig. 1
a schematic plan view of a system consisting of a powder metering device and a powder supply device according to the invention with two counter-rotating stirrers, and
Fig. 2
in a sectional view of the powder supply device Fig. 1 with details of its smoothing device designed as an agitator.

Fig. 1 zeigt in einer schematischen Draufsicht einen Ausschnitt eines Systems, welches einen Pulverdosierer 1 und eine Pulverbereitstellungseinrichtung 4 für den Pulverdosierer 1 umfasst. Teil der erfindungsgemäßen Pulverbereitstellungseinrichtung 4 ist ein Pulverbehälter 5, in dem ein Pulverbett 3 aus einem pulvrigen Produkt bereitgehalten wird. Das pulvrige Produkt ist hier ein pharmazeutisches Präparat. Es kommen aber auch andere pulvrige Produkte zur Bildung des Pulverbetts 3 und zur Prozessierung mittels der Pulverbereitstellungseinrichtung 4 in Betracht. Mittels des Pulverdosierers 1 werden Teilmengen des pulvrigen Produkts aus dem Pulverbett 3 entnommen und jeweils als definierte Dosiermenge abgegrenzt. Im gezeigten Ausführungsbeispiel ist der Pulverdosierer 1 eine nur schematisch angedeutete Stechheberstation mit beispielhaft vier angedeuteten Stechhebern 2, deren zylindrische Hülsen von oben, also senkrecht zur Zeichnungsebene der Fig. 1 in das Pulverbett 3 eintauchen, um dort in bekannter Weise jeweils eine Pulvermenge abzugrenzen, zu kompaktieren und für die Weiterverarbeitung, insbesondere für die Überführung in nicht dargestellte Zielbehälter zu entnehmen. Anstelle einer Stechheberstation können aber auch andere Bauformen eines Pulverdosierers 1 zum Einsatz kommen. Fig. 1 shows a schematic plan view of a section of a system which comprises a powder metering device 1 and a powder supply device 4 for the powder metering device 1. Part of the powder supply device 4 according to the invention is a powder container 5, in which a powder bed 3 made of a powdery product is kept ready. The powdery product here is a pharmaceutical preparation. However, other powdery products are also suitable for forming the powder bed 3 and for processing by means of the powder supply device 4. Partial quantities of the powdery product are removed from the powder bed 3 by means of the powder dosing device 1 and each delimited as a defined dosing amount. In the exemplary embodiment shown, the powder metering device 1 is an only schematically indicated piercing station with four piercing levers 2, for example, the cylindrical ones of which are indicated Sleeves from above, i.e. perpendicular to the plane of the drawing Fig. 1 Immerse in the powder bed 3 in order to delimit, compact there in a known manner and to remove it for further processing, in particular for transfer into target containers (not shown). Instead of a piercing station, other types of powder metering device 1 can also be used.

Die Pulverbereitstellungseinrichtung 4 umfasst neben dem genannten topfförmigen Pulverbehälter 5 eine Glättungseinrichtung 6 für das Pulverbett 3, deren weitere Einzelheiten sich aus der Zusammenschau der Fig. 1 mit Fig. 2 ergeben. Fig. 2 zeigt in einer Schnittdarstellung die Pulverbereitstellungseinrichtung nach Fig. 1 in einer Schnittebene senkrecht zur Zeichnungsebene nach Fig. 1. Aus der Zusammenschau der Fig. 1 und 2 ergibt sich, dass die Glättungseinrichtung 6 ebenso wie der Pulverdosierer 1 ortsfest gelagert ist, während der Pulverbehälter 5 um eine vertikale Drehachse 12 drehbar gelagert ist und im Betrieb um diese Drehachse entsprechend einem Pfeil 13 (Fig. 1) drehend angetrieben wird. Das Pulverbett 3 im Pulverbehälter 5 folgt dieser Drehbewegung, so dass es gegenüber dem fest positionierten Pulverdosierer 1 und auch gegenüber der fest positionieren Glättungseinrichtung 6 eine Relativbewegung ausübt.The powder supply device 4 comprises, in addition to the pot-shaped powder container 5 mentioned, a smoothing device 6 for the powder bed 3, the further details of which can be found in the overview of Fig. 1 With Fig. 2 result. Fig. 2 shows the powder supply device in a sectional view Fig. 1 in a section plane perpendicular to the plane of the drawing Fig. 1 , From the synopsis of Fig. 1 and 2 it follows that the smoothing device 6, like the powder metering device 1, is mounted in a stationary manner, while the powder container 5 is mounted such that it can rotate about a vertical axis of rotation 12 and during operation about this axis of rotation according to an arrow 13 ( Fig. 1 ) is driven in rotation. The powder bed 3 in the powder container 5 follows this rotary movement, so that it exerts a relative movement with respect to the fixedly positioned powder metering device 1 and also with respect to the firmly positioned smoothing device 6.

Die genannte Drehbewegung von Pulverbehälter 5 und Pulverbett 3 um die Drehachse 12 ist intermittierend bzw. getaktet. Beim oben umrissenen Abmessen der einzelnen Pulverdosiermengen, also bei Eintauchen der Stechheberhülse in das Pulverbett 3 bis hin zum Zurückziehen desselben ist die Drehbewegung angehalten. Danach wird die Drehbewegung der Einheit aus Pulverbehälter 5 und Pulverbett 3 in Gang gesetzt und nach Ausführung eines definierten Winkelschritts erneut angehalten, wonach der Abmessungs- bzw. Dosiervorgang erneut beginnt. Das Pulverbett 3 weist gemäß der Darstellung nach Fig. 2 eine Oberfläche 19 auf, in der die Stechheber 2 (Fig. 1) nach dem Herausziehen Krater hinterlassen. Die Ausführung des genannten Winkelschritts trägt dazu bei, dass der Pulverdosierer 1 bei jedem Abmessungs- bzw. Dosiervorgang ein Pulverbett 3 mit möglichst homogenen Eigenschaften und möglichst ungestörter Oberfläche 19 vorfindet.The mentioned rotary movement of powder container 5 and powder bed 3 about the axis of rotation 12 is intermittent or clocked. When the individual powder dosing quantities outlined above, that is to say when the plunger sleeve is immersed in the powder bed 3 until the same is withdrawn, the rotary movement is stopped. The rotary movement of the powder container 5 and powder bed 3 unit is then started and stopped again after a defined angular step has been carried out, after which the dimensioning or dosing process begins again. The powder bed 3 demonstrates as shown Fig. 2 a surface 19 in which the plunger 2 ( Fig. 1 ) leave craters after pulling out. The execution of the said angular step helps to ensure that the powder dispenser 1 finds a powder bed 3 with the most homogeneous properties possible and the most undisturbed surface 19 with each dimensioning or dosing process.

Eventuell vorhandene Krater in der Oberfläche 19 oder auch andere durch den Pulverdosierer 1 hervorgerufene Störungen im Pulverbett 3 wandern zunächst mit der Drehbewegung des Pulverbehälters 5 in Richtung des Pfeils 13 mit. Zur Beseitigung solcher Störungen ist in Drehrichtung (Pfeil 13) hinter dem Pulverdosierer 1 die oben schon erwähnte Glättungseinrichtung 6 für das Pulverbett 3 positioniert. Die Glättungseinrichtung 6 umfasst ein Rührwerk 7, welches seinerseits mindestens einen, hier zwei Rührer 8, 9 umfasst. Die beiden Rührer 8, 9 weisen Antriebswellen auf, mittels derer sie in einer ortsfesten, nicht mit dem Pulverbehälter mitdrehenden Lagerplatte 18 drehbar gelagert sind. Dabei weisen der eine Rührer 8 eine vertikale Drehachse 14 und der andere Rührer 9 eine vertikale Drehachse 16 auf. Beide Drehachsen 14, 16 der Rührer 8, 9 sind achsparallel zueinander und auch achsparallel zur Drehachse 12 des Pulverbehälters 5.Possibly existing craters in the surface 19 or also other disturbances in the powder bed 3 caused by the powder dosing device 1 initially migrate with the rotating movement of the powder container 5 in the direction of the arrow 13. To eliminate such faults, the above-mentioned smoothing device 6 for the powder bed 3 is positioned behind the powder metering device 1 in the direction of rotation (arrow 13). The smoothing device 6 comprises an agitator 7, which in turn comprises at least one, here two agitators 8, 9. The two stirrers 8, 9 have drive shafts, by means of which they are rotatably mounted in a fixed bearing plate 18 which does not rotate with the powder container. One stirrer 8 has a vertical axis of rotation 14 and the other stirrer 9 has a vertical axis of rotation 16. Both axes of rotation 14, 16 of the stirrers 8, 9 are axially parallel to one another and also axially parallel to the axis of rotation 12 of the powder container 5.

Beide Rührer 8, 9 weisen jeweils mindestens ein, hier vier axiale Mischelemente 10 sowie optional auch mindestens ein, hier vier radiale Mischelemente 11 jeweils aus gebogenem Draht auf. Die axialen Mischelemente 10 verlaufen parallel zur jeweiligen Drehachse 14, 16, können aber auch in einem schrägen Winkel dazu liegen und beispielsweise schraubenförmig verlaufen. Die radialen Mischelemente verlaufen radial zur jeweiligen Drehachse 14, 16. Auch für sie gilt, dass sie nicht exakt diesen Verlauf haben müssen, sondern auch in einem schrägen Winkel dazu liegen und beispielsweise spiralig verlaufen können. Die Rührer 8, 9 sind derart positioniert, dass sie mit ihren axialen und radialen Mischelementen 10, 11 in den Innenraum des Pulverbehälters 5 und dort in das Pulverbett 3 hineinragen. Die Eintauchtiefe der Rührer 8, 9 unter die Oberfläche 19 des Pulverbettes 3 reicht praktisch bis zum Boden des Pulverbehälters 5. Jedenfalls ist sie bevorzugt mindestens so groß wie die Eintauchtiefe der Stechheber 2.Both stirrers 8, 9 each have at least one, here four axial mixing elements 10 and optionally also at least one, here four radial mixing elements 11 each made of bent wire. The axial mixing elements 10 run parallel to the respective axis of rotation 14, 16, but can also lie at an oblique angle thereto and, for example, run helically. The radial mixing elements run radially with respect to the respective axis of rotation 14, 16. It also applies to them that they do not have to have exactly this course, but also lie at an oblique angle thereto and can for example run spirally. The stirrers 8, 9 are positioned such that their axial and radial mixing elements 10, 11 protrude into the interior of the powder container 5 and there into the powder bed 3. The immersion depth of the stirrers 8, 9 below the surface 19 of the powder bed 3 practically extends to the bottom of the powder container 5. In any case, it is preferably at least as great as the immersion depth of the piercing lifter 2.

Aus der Draufsicht nach Fig. 1 ergibt sich noch, dass beide Rührer 8, 9 in Drehrichtung des Pulverbehälters 5 auf gleicher Relativposition zum Pulverdosierer 1 liegen, jedoch in radialer Richtung zueinander beabstandet sind. Es kann aber auch ein Positionsversatz beider Rührer 8, 9 in Drehrichtung des Pulverbehälters 5 zweckmäßig sein. Außerdem ist in Fig. 1 zu erkennen, dass beide Rührer 8, 9 im Betrieb um ihre jeweiligen Drehachsen 14, 16 gegenläufig angetrieben werden, wie dies durch Pfeile 15, 17 kenntlich gemacht ist. Der Abstand der beiden Drehachsen 14, 16 ist kleiner als der Durchmesser der Rührer 8, 9, in dessen Folge die Mischelemente 10, 11 beider Rührer 8, 9 ineinander kämmen. Durch geeigneten Drehwinkelversatz wird dabei eine Kollision der Mischelemente 8, 9 miteinander verhindert. Insgesamt erzeugen beide Rührer 8, 9 eine lückenfreie Wirkbreite, die sich radial zur Drehachse 12 des Pulverbehälters 5 soweit erstreckt, dass die ebenfalls radial zur Drehachse 12 des Pulverbehälters 5 gemessene Wirkbreite des Pulverdosierers 1 bzw. seiner sämtlichen Stechheber 2 vollständig abgedeckt ist. Der im Pulverbett 3 sich einstellende Nachlauf des gesamten Pulverdosierers 1 wird vollständig von den Mischelementen 8, 9 erfasst.From the top view Fig. 1 it also follows that both stirrers 8, 9 lie in the same direction of rotation of the powder container 5 in the same relative position as the powder metering device 1, however are spaced apart in the radial direction. However, it may also be expedient to position the two stirrers 8, 9 in the direction of rotation of the powder container 5. In addition, in Fig. 1 to recognize that both stirrers 8, 9 are driven in opposite directions about their respective axes of rotation 14, 16 during operation, as is indicated by arrows 15, 17. The distance between the two axes of rotation 14, 16 is smaller than the diameter of the stirrers 8, 9, as a result of which the mixing elements 10, 11 of both stirrers 8, 9 mesh with one another. A suitable rotation angle offset prevents a collision of the mixing elements 8, 9 with one another. Overall, both stirrers 8, 9 produce a gap-free effective width, which extends radially to the axis of rotation 12 of the powder container 5 to such an extent that the effective width of the powder metering device 1, or all of its piercing levers 2, which is also measured radially to the axis of rotation 12 of the powder container 5, is completely covered. The wake of the entire powder dosing device 1 occurring in the powder bed 3 is completely captured by the mixing elements 8, 9.

Die Drehbewegung beider Rührer 8, 9 ist an die Drehbewegung des Pulverbehälters 5 gekoppelt. Dies kann beispielsweise durch einen gemeinsamen Antrieb und eine mechanische Zwangskopplung mittels Zahnrädern, aber auch durch eine geeignete elektronische Steuerung bei separaten Antrieben herbeigeführt werden. Jedenfalls stehen die Rührer 8, 9 still, wenn der Pulverbehälter 5 still steht. Und sie drehen sich, wenn auch der Pulverbehälter 5 eine Drehbewegung ausführt. In Beschleunigungs- und Verzögerungsphasen des Pulverbehälters 5 führen auch die Rührer 8, 9 korrespondierend beschleunigte oder verzögerte Drehbewegungen aus.The rotary movement of the two stirrers 8, 9 is coupled to the rotary movement of the powder container 5. This can be brought about, for example, by a common drive and a mechanical positive coupling by means of gear wheels, but also by a suitable electronic control in the case of separate drives. In any case, the stirrers 8, 9 stand still when the powder container 5 stands still. And they rotate when the powder container 5 also rotates. In the acceleration and deceleration phases of the powder container 5, the stirrers 8, 9 also perform correspondingly accelerated or decelerated rotary movements.

Insgesamt wird erreicht, dass mittels des Rührwerks 7 Störungen des Pulverbetts 3 im Nachlauf des Pulverdosierers 1 beseitigt werden, und dass dem Pulverdosierer 1 kontinuierlich ein Pulverbett 3 mit homogenen Pulvereigenschaften und mit einer Oberfläche 19 auf konstantem Höhenniveau zugeführt wird.Overall, it is achieved that disturbances in the powder bed 3 in the wake of the powder metering device 1 are eliminated by means of the agitator 7, and that the powder metering device 1 is continuously supplied with a powder bed 3 with homogeneous powder properties and with a surface 19 at a constant height level.

Claims (6)

Pulverbereitstellungseinrichtung (4) für einen Pulverdosierer (1), insbesondere für eine Stechheberstation, mit einem drehend antreibbaren Pulverbehälter (5) zur Aufnahme eines Pulverbetts (3), und mit einer ortsfest gelagerten Glättungseinrichtung (6) für das Pulverbett (3),
dadurch gekennzeichnet, dass die ortsfest gelagerte Glättungseinrichtung (6) ein Rührwerk (7) mit mindestens einem in den Innenraum des Pulverbehälters (5) ragenden, drehend antreibbaren Rührer (8, 9) umfasst.Powder supply device (4) for a powder dosing device (1), in particular for a lancing station, with a powder container (5) which can be driven in rotation to receive a powder bed (3), and with a stationary smoothing device (6) for the powder bed (3),
characterized in that the stationary smoothing device (6) comprises a stirrer (7) with at least one stirrer (8, 9) projecting into the interior of the powder container (5) and can be driven in rotation. Pulverbereitstellungseinrichtung nach Anspruch 1,
dadurch gekennzeichnet, dass der mindestens eine Rührer (8, 9) eine vertikal ausgerichtete Drehachse aufweist.Powder supply device according to claim 1,
characterized in that the at least one stirrer (8, 9) has a vertically oriented axis of rotation. Pulverbereitstellungseinrichtung nach Anspruch 1 oder 2,
dadurch gekennzeichnet, dass das Rührwerk (7) zwei gegenläufig antreibbare und ineinander greifende Rührer (8, 9) aufweist.Powder supply device according to claim 1 or 2,
characterized in that the agitator (7) has two oppositely drivable and intermeshing agitators (8, 9). Pulverbereitstellungseinrichtung nach einem der Ansprüche 1 bis 3,
dadurch gekennzeichnet, dass der Rührer (8, 9) mindestens ein axiales Mischelement (10) aufweist.Powder supply device according to one of claims 1 to 3,
characterized in that the stirrer (8, 9) has at least one axial mixing element (10). Pulverbereitstellungseinrichtung nach einem der Ansprüche 1 bis 4,
dadurch gekennzeichnet, dass der Rührer (8, 9) mindestens ein radiales Mischelement (11) aufweist.Powder supply device according to one of claims 1 to 4,
characterized in that the stirrer (8, 9) has at least one radial mixing element (11). Pulverbereitstellungseinrichtung nach einem der Ansprüche 1 bis 5,
dadurch gekennzeichnet, dass die Drehbewegung des Rührers (8, 9) an die Drehbewegung des Pulverbehälters (5) gekoppelt ist.Powder supply device according to one of claims 1 to 5,
characterized in that the rotary movement of the stirrer (8, 9) is coupled to the rotary movement of the powder container (5).
EP18187934.7A 2018-08-08 2018-08-08 Powder provision device for a powder metering apparatus Active EP3608015B1 (en)

Priority Applications (4)

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EP18187934.7A EP3608015B1 (en) 2018-08-08 2018-08-08 Powder provision device for a powder metering apparatus
CA3050484A CA3050484A1 (en) 2018-08-08 2019-07-24 Powder provisioning device for a powder doser
US16/534,784 US11279502B2 (en) 2018-08-08 2019-08-07 Powder provisioning device for a powder doser
CN201910729446.0A CN110813157B (en) 2018-08-08 2019-08-08 Powder supply device for powder dispenser

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CN110813157A (en) 2020-02-21
CA3050484A1 (en) 2020-02-08
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CN110813157B (en) 2022-11-01
US11279502B2 (en) 2022-03-22
US20200047925A1 (en) 2020-02-13

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