EP3589947A1 - Procédé et dispositif pour déterminer un traitement non thérapeutique de la cavité buccale - Google Patents

Procédé et dispositif pour déterminer un traitement non thérapeutique de la cavité buccale

Info

Publication number
EP3589947A1
EP3589947A1 EP18705627.0A EP18705627A EP3589947A1 EP 3589947 A1 EP3589947 A1 EP 3589947A1 EP 18705627 A EP18705627 A EP 18705627A EP 3589947 A1 EP3589947 A1 EP 3589947A1
Authority
EP
European Patent Office
Prior art keywords
therapeutic treatment
measuring
determining
user
oral cavity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP18705627.0A
Other languages
German (de)
English (en)
Inventor
Andreas Bock
Thomas Welss
Kristin Miehlich
Claudia Hundeiker
Matthias Frischmann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Henkel AG and Co KGaA
Original Assignee
Henkel AG and Co KGaA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Henkel AG and Co KGaA filed Critical Henkel AG and Co KGaA
Publication of EP3589947A1 publication Critical patent/EP3589947A1/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/497—Physical analysis of biological material of gaseous biological material, e.g. breath
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/08—Detecting, measuring or recording devices for evaluating the respiratory organs
    • A61B5/082—Evaluation by breath analysis, e.g. determination of the chemical composition of exhaled breath
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/08—Detecting, measuring or recording devices for evaluating the respiratory organs
    • A61B5/097—Devices for facilitating collection of breath or for directing breath into or through measuring devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0002—Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network
    • A61B5/0015—Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network characterised by features of the telemetry system
    • A61B5/0022—Monitoring a patient using a global network, e.g. telephone networks, internet
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6887—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient mounted on external non-worn devices, e.g. non-medical devices
    • A61B5/6898—Portable consumer electronic devices, e.g. music players, telephones, tablet computers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/497—Physical analysis of biological material of gaseous biological material, e.g. breath
    • G01N33/4975—Physical analysis of biological material of gaseous biological material, e.g. breath other than oxygen, carbon dioxide or alcohol, e.g. organic vapours

Definitions

  • the invention relates to methods and arrangements for determining a non-therapeutic treatment of the oral cavity.
  • a method of determining a non-therapeutic mouthwash treatment comprising measuring volatile organic compounds in air expired from the oral cavity, determining a breathing air load based on the measured concentration, and determining a non-therapeutic mouthwash treatment based on the determined breathing air load.
  • an arrangement for determining a non-therapeutic treatment of the oral cavity is provided.
  • a method for monitoring the success of a non-therapeutic oral cavity treatment is provided.
  • Figure 1 shows an arrangement for determining a non-therapeutic treatment of the oral cavity.
  • FIG. 2 shows a graphical representation of the breathing air load of a user over time.
  • FIG. 3 is a flow chart illustrating a method for determining a non-therapeutic treatment of the oral cavity.
  • Figure 4 shows an arrangement for determining a non-therapeutic treatment of the oral cavity.
  • Figure 5 shows a method for monitoring the success of a non-therapeutic oral cavity treatment.
  • Halitosis is caused by the breakdown of food components by bacteria. Most are organic and sulfur-containing, volatile substances that lead to malodorous breath. By gas chromatography, about 1000 different volatile compounds have been identified that may be mixed with the exhaled breath in human halitosis. These include sulfur compounds such as hydrogen sulfide (H2S), methanethiol (methyl mercaptan) and dimethyl sulfide, as well as amines, diamines and other nitrogen compounds such as 1, 5-diaminopentane, indole and skatole, ketones such as acetone (propanone) and short-chain carboxylic acids (propionic acid, butyric acid). These substances arise z. B. by the bacterial decomposition of organic substances from food remnants, saliva or dead tissue material (shed epithelial cells).
  • halitosis can be detected by using a sensor that measures specific volatile organic volatile organic compounds (VOCs), for example, one or more of the volatile compounds mentioned above.
  • VOCs volatile organic volatile organic compounds
  • a user's breathing air load is determined in this way, and based on the determined respiratory air load, a non-therapeutic treatment can be determined and proposed to the user.
  • Volatile organic compounds is the collective term for organic, ie carbon-containing substances which evaporate easily (are volatile) or are present as gas even at low temperatures (eg room temperature).
  • respiratory air pollution is understood to be the odor load of the exhaled air.
  • breathing air stress means that substances in the exhaled air of a human being (such as those mentioned above) are perceived as malodorous, and in a significant amount so that they appear as (noticeable) halitosis ,
  • halitosis What is categorized as noticeable halitosis, for example, can be determined with a sniffer study. Sniffers can be skilled assessors, for example, regularly trained by an institute and then selected for their suitability. By means of dynamic olfactometry the odor threshold of the testers can be checked. Similarly, levels of VOCs in the exhaled air can be assigned degrees of halitosis. For example, assuming from 1 to 1000 parts per billion (VPC) of exhaled air in VOC, value ranges of VOC concentrations, as judged by sniffer levels, may be assigned to respiratory effort (ie, halitosis levels), for example, as shown in Table 1 ,
  • Figure 1 shows an arrangement for determining a non-therapeutic treatment of the oral cavity.
  • the concentration of VOCs in the air (breath) 102 exhaled from a user's mouth 101 is measured by a measuring device 103.
  • the measuring device 103 uses a technique for quantifying VOC in the breathing air. For example, it has a selective sensor that specifically measures one or more volatile organic compounds or groups of volatile organic compounds (VOCs) in the breath 102.
  • VOCs volatile organic compounds
  • the measuring device 103 may measure the VOC concentration using, for example, a redox sensor, a photoionization detection (PID) sensor, or based on gas chromatography (GC) or a combination thereof.
  • An analysis device 104 is coupled to the measuring device 103.
  • the analysis device 104 (and possibly also the measuring device 103) can be, for example, an electronic device, eg a portable electronic device such as a smartphone, a smartband, a smartwatch, a PDA (Personal Digital Assistant), a tablet computer (or integrated therein) be realized by this) but also be an arbitrary computer.
  • the measuring device 103 may have any size. To allow the user to carry the measuring device 103 with him (and to use it, for example, with his smartphone), it may for example have a size that fits easily into hand and trouser pockets (eg base ⁇ 16 cm 2 , height ⁇ 1 cm).
  • the measuring device 103 is a device for quantifying VOCs in the exhaled air 102 and measures, for example, the VOC concentration in the exhaled air 102 in a particular unit (e.g., ppb).
  • the analysis device 104 determines from the measured VOC concentration a breathing air load, for example in the form of a breathing air load value. For example, analyzer 104 generates a value of the respiratory air load in an arbitrary unit, e.g. a severity of bad breath, or even a verbal guide for the user based on the measured VOC concentration. For example, the analyzer 104 may determine a halitosis category from the measured VOC concentration as shown in Table 1, optionally with a higher number of gradings than indicated in Table 1.
  • the analysis device 104 can then determine a non-therapeutic treatment proposal based on the determined respiratory air load and, for example, display it on a display 105 coupled to the analysis device 104 (for example optionally the display of the smartphone or the tablet computer).
  • the arrangement 100 has a screen, a display or a touchscreen in order to provide a user with information, for example with determined recommendations for a non-therapeutic treatment.
  • the arrangement 100 may also have an audio output for this purpose.
  • the analyzer may execute analysis software (e.g., an app) that performs the functions described above and below.
  • analysis software e.g., an app
  • analyzer 104 may derive and display product recommendations for individual oral hygiene, such as recommendations for improving individualized dental care, such as tooth brushing.
  • the analyzer 104 may suggest to the user to brush the teeth more frequently or mouthwash (with suggestions as to which mouthwash the user could use or which toothpaste the user could use) or even recommend a visit to the dentist.
  • the recommendation of a visit to a dentist can link the analysis device 104 directly to a software (eg an app) that makes it possible to make an appointment with a dentist.
  • a software eg an app
  • Other nontherapeutic treatments of the oral cavity may include the use of specialized toothbrushes such as interdental brushes, toothbrushes for implants or dentures, tongue cleaners, compositions, particularly gels, for application to the teeth and / or gums, mouthwashes, mouth sprays and / or chewing gums.
  • the analyzer 104 may also issue a warning to the user that the halitosis may result in a negative reaction in the presence of other persons when the determined respiratory air load reaches a certain level (eg, "medium halitosis” or "bad halitosis” according to US Pat Categorization according to Table 1).
  • a certain level eg, "medium halitosis” or "bad halitosis” according to US Pat Categorization according to Table 1).
  • the analysis device 104 may also provide nutritional advice for better breath as a treatment suggestion.
  • the analyzer 104 may also indicate that everything is in order, and the treatment proposal in this case may be seen as keeping the current habits.
  • the treatment proposal may include a product recommendation that depends on the respiratory air load (i.e., the level of respiratory air load).
  • the non-therapeutic treatment may be additionally determined based on predetermined data.
  • the predetermined data can be stored, for example, in a memory and / or provided by an external data processing system.
  • the given data can be in the form of a database.
  • the given data may contain literature data, for example concerning the compatibility and ingredients of cosmetics, or also data regarding treatment courses of other consumers. Accordingly, the data may contain information about cosmetics, e.g. their ingredients and effects on body parts.
  • the specified data can be obtained on request of the user or regularly from an external data processing system.
  • the analysis device 104 may, for example, a communication interface for data transmission with a server 107 (or in general an external data processing system) exhibit.
  • the server 107 may, for example, be contactable via the Internet and may for example be part of a server network that implements a cloud.
  • the measuring device 103 and the analysis device 104 are likewise connected by means of a communication interface.
  • the communication interfaces can be set up, for example, for wired or wireless communication.
  • data can be transferred via USB (Universal Serial Bus), WLAN (Wireless Local Area Network), NFC (Near-Field Communication), Thread, ZigBee and / or Bluetooth.
  • the two communication interfaces may have corresponding communication circuits and / or be coupled to these.
  • the analysis device 104 may have a processor, which is coupled to the communication interface or interfaces, so that a data transmission between the processor and the measuring device 103 or the server 107 can take place.
  • the communication interfaces can also be completely or partially integrated in the processor.
  • the processor can be for example a microprocessor, a microcontroller or an ASIC (Application Specific Integrated Circuit).
  • the processor can be set up, for example, by means of software for the above and below (also combined) embodiments.
  • the software may be a mobile application, a web application or a desktop application.
  • the software may be stored in a memory of the analysis device and / or at least partially in an external data processing system, such as the server 107, and may be accessible to the processor.
  • the analyzer e.g. its processor controls and controls, for example, the detection system to perform the measurement.
  • the analysis device 104 can compare the measuring information with information stored in a memory, for example a database, or with information that it receives from the server 107.
  • the measurement information can be assigned one or more categories, for example based on predetermined value ranges.
  • the analyzer 104 may optionally include an input device. Data can be input and queried via the input device, which can be used to determine a non-therapeutic treatment. For example, a user may indicate an allergen and / or allergen known to him, and thus, in determining a non-therapeutic treatment, the suggestion of an allergen may be prevented.
  • the analyzer 104 may prompt the user for input of data via a corresponding display. The determination of the breathing air load can be carried out for a user over a longer period of time. The analyzer 104 may then record a status of its breath based on the measured respiratory effort over an extended period of time.
  • the analyzer 104 may then, for example, standardize and objectively assess the success of non-therapeutic treatment that the user performs during the time period (and was suggested to him, for example, at the beginning of the time period by the analyzer 104), e.g. at home, for example, when the user uses their smartphone or tablet computer. This allows the user to control the individual effectiveness of an oral hygiene product and / or oral hygiene and may increase (depending on the success) his motivation to carry out a similar treatment in the longer term.
  • the analysis device 104 allows the control and tracking of a user's breath load by presenting the measurement results over time.
  • the analysis device 104 can graphically display the course of the determined respiratory air load, as shown in FIG.
  • FIG. 2 shows a graphical representation 200 of the breathing air load of a user over time.
  • the analyzer 204 determines a user's breath load every day over a period of several weeks.
  • the days are plotted along the x-axis 201 and the respiratory air load is indicated (in some unit, e.g., a VOC concentration) according to the y-axis scale 202.
  • the values are connected in this example to a smoothed curve 203 to indicate continuous development.
  • the analyzer 104 may also determine the breathing air load at shorter time intervals and generate the curve 203 based on a higher number (or denser) of determined values of the respiratory air load.
  • the analysis device 104 can in turn give care and product recommendations. For example, if the treatment fails to improve, the analyzer 104 may recommend other or more metered products.
  • the analyzer 104 in determining non-therapeutic treatment (eg, care and product recommendations), may also include the user's answers to questions regarding his general dental status (for example, presence of dentures, such as Implants, bridges, etc. or braces), their oral hygiene habits (for example name of oral hygiene products used, frequency of brushing teeth, use of special toothbrushes such as interdental brushes or tongue brushes), their dietary habits, general health (eg about illness, allergies, medication) and more Incorporate behaviors (such as smoking habits).
  • the analysis device 104 may display corresponding questions on the display 105 and receive and process the responses via an input device (eg, a keyboard or a touch screen), ie, determine the non-therapeutic treatment based on the responses.
  • the analyzer 104 may also base literature data on the determination of non-therapeutic treatment, as well as the treatment success of non-therapeutic treatments of other users (for example, the same software or app using the analyzer 104).
  • the respiratory air loads detected during a non-therapeutic treatment are uploaded to a server 107 (e.g., a cloud), e.g. along with a user's profile, and the analyzer 104 may download such data from other users, such as users having a profile similar to the user of the analyzer 104, to determine which treatment methods are successful for users of such or similar profile , It can also be determined on the server side which treatment methods for which user profiles are successful and the analysis device 104 can download this information and include it in the determination of the non-therapeutic treatment.
  • a server 107 e.g., a cloud
  • the analyzer 104 may download such data from other users, such as users having a profile similar to the user of the analyzer 104, to determine which treatment methods are successful for users of such or similar profile . It can also be determined on the server side which treatment methods for which user profiles are successful and the analysis device 104 can download this information and include it in the determination of the non-therapeutic treatment.
  • the user profile may include oral hygiene habits, eating habits, drinking habits, smoking habits, gender, height, age, weight, etc.
  • FIG. 3 shows a flow chart 300 illustrating a method for determining a non-therapeutic treatment of the oral cavity.
  • volatile organic compounds are measured in exhaled air from the mouth.
  • a breathing air load is determined based on the measured concentration.
  • a non-therapeutic oral cavity treatment is determined based on the determined respiratory effort.
  • a user's breath load is measured by measuring the concentration of volatile organic constituents in the exhaled air and determining a treatment proposal based on the breath air load.
  • the method allows a user to receive individual care recommendations and product recommendations that address their needs.
  • FIG. 4 shows an arrangement 400 for determining a non-therapeutic treatment of the oral cavity.
  • the assembly 400 includes a measuring device 401 configured to measure volatile organics in air exhaled from the oral cavity.
  • the success of the non-therapeutic treatment is determined based on the determined respiratory air loads.
  • the user can be offered a recommended product directly for sale and the user can initiate the purchase by entering the purchase.
  • the user can also be offered further information on the purchase.
  • This further information may refer to more detailed treatment and application instructions.
  • a software / app receives the request that the user wants to purchase the oral hygiene product, stores the request, and / or submits the request to a trading company that distributes the oral hygiene products.
  • the user may be prompted by the software / app to enter his personal data (address, bank information, delivery preference, etc.) via the input unit.
  • the user can be indicated where (for example, drugstore, pharmacy, etc.) he can purchase the oral hygiene product.
  • the software / app may be the same software or app that the analyzer 104 uses.
  • Suitable ingredients of oral hygiene products include, for example, zinc acetate, chlorhexidine, fluorides, such as sodium fluoride, stannous fluoride, and / or amine fluorides, such as olaflur, essential oils, such as thymol , Eucalyptol, menthol and / or methyl salicylate, zinc lactate, cetylpyridinium chloride and / or zinc chloride.
  • fluorides such as sodium fluoride, stannous fluoride, and / or amine fluorides, such as olaflur
  • essential oils such as thymol , Eucalyptol, menthol and / or methyl salicylate
  • zinc lactate cetylpyridinium chloride and / or zinc chloride
  • cetylpyridinium chloride and / or zinc chloride.
  • Embodiment 3 is the method of Embodiment 1 or 2, wherein measuring volatiles includes measuring a concentration of volatile organic compounds in the exhaled air.
  • Embodiment 20 is the arrangement according to any one of Embodiments 16 to 19, wherein the measurement of volatile components comprises measuring a concentration of volatile components by means of a redox sensor, a photoionization detection (PID) sensor and / or based on gas chromatography (GC) or a Combination thereof.
  • Embodiment 21 is the arrangement according to one of the embodiments 16 to 20, further comprising displaying an indication of the determined non-therapeutic treatment on a display.
  • Embodiment 25 is the assembly of Embodiment 24 wherein the personal information includes one or more of information about the age, sex, height, weight, allergies / allergens, and habits of the user.
  • Embodiment 30 is the arrangement according to one of the embodiments 16 to 29, comprising storing the determined respiratory air load on a server.
  • Embodiment 31 is a method of monitoring the success of a non-therapeutic oral cavity treatment as shown in FIG.
  • Embodiment 34 is the method of any of embodiments 31-33, wherein measuring volatiles includes measuring a concentration of volatile organic constituents in the exhaled air.
  • Embodiment 39 is the method according to any of embodiments 31 to 38, wherein the non-therapeutic treatment comprises the use of an oral hygiene product having a particular chemical composition.
  • Embodiment 46 is the method according to one of the embodiments 31 to 45, comprising storing the determined respiratory air load on a server.

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Pulmonology (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Physiology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)

Abstract

L'invention concerne un procédé pour déterminer un traitement non thérapeutique de la cavité buccale, consistant à mesurer (103, 301) des composants organiques volatiles dans de l'air (102) expiré par la cavité buccale (101), à déterminer (104, 302) une charge de l'air de respiration en fonction de la concentration mesurée, et à déterminer (104, 303) un traitement non thérapeutique de la cavité buccale en fonction de la charge de l'air de respiration déterminée.
EP18705627.0A 2017-03-03 2018-02-15 Procédé et dispositif pour déterminer un traitement non thérapeutique de la cavité buccale Withdrawn EP3589947A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102017203499.8A DE102017203499A1 (de) 2017-03-03 2017-03-03 Verfahren und Anordnung zum Ermitteln einer nicht-therapeutischen Behandlung des Mundraums
PCT/EP2018/053778 WO2018158083A1 (fr) 2017-03-03 2018-02-15 Procédé et dispositif pour déterminer un traitement non thérapeutique de la cavité buccale

Publications (1)

Publication Number Publication Date
EP3589947A1 true EP3589947A1 (fr) 2020-01-08

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Family Applications (1)

Application Number Title Priority Date Filing Date
EP18705627.0A Withdrawn EP3589947A1 (fr) 2017-03-03 2018-02-15 Procédé et dispositif pour déterminer un traitement non thérapeutique de la cavité buccale

Country Status (4)

Country Link
US (1) US20200229734A1 (fr)
EP (1) EP3589947A1 (fr)
DE (1) DE102017203499A1 (fr)
WO (1) WO2018158083A1 (fr)

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US11932080B2 (en) 2020-08-20 2024-03-19 Denso International America, Inc. Diagnostic and recirculation control systems and methods
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US12017506B2 (en) 2020-08-20 2024-06-25 Denso International America, Inc. Passenger cabin air control systems and methods
US11760170B2 (en) 2020-08-20 2023-09-19 Denso International America, Inc. Olfaction sensor preservation systems and methods
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US11636870B2 (en) 2020-08-20 2023-04-25 Denso International America, Inc. Smoking cessation systems and methods
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US20200229734A1 (en) 2020-07-23
WO2018158083A1 (fr) 2018-09-07
DE102017203499A1 (de) 2017-07-06

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