EP3455348A4 - Hierarchisch strukturierte proteinmaterialien für dreidimensionale (3d) zelluläre unterstützungssysteme - Google Patents

Hierarchisch strukturierte proteinmaterialien für dreidimensionale (3d) zelluläre unterstützungssysteme Download PDF

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Publication number
EP3455348A4
EP3455348A4 EP17796855.9A EP17796855A EP3455348A4 EP 3455348 A4 EP3455348 A4 EP 3455348A4 EP 17796855 A EP17796855 A EP 17796855A EP 3455348 A4 EP3455348 A4 EP 3455348A4
Authority
EP
European Patent Office
Prior art keywords
dimensional
support systems
hierarchically structured
protein materials
structured protein
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP17796855.9A
Other languages
English (en)
French (fr)
Other versions
EP3455348A1 (de
Inventor
Stacy RAMCHARAN
Luis Solorio
Jacob JORDAHL
Joerg Lahann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Michigan
Original Assignee
University of Michigan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Michigan filed Critical University of Michigan
Publication of EP3455348A1 publication Critical patent/EP3455348A1/de
Publication of EP3455348A4 publication Critical patent/EP3455348A4/de
Pending legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0062—General methods for three-dimensional culture
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/10—Mineral substrates
    • C12N2533/14—Ceramic
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/30—Synthetic polymers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/30—Synthetic polymers
    • C12N2533/40—Polyhydroxyacids, e.g. polymers of glycolic or lactic acid (PGA, PLA, PLGA); Bioresorbable polymers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/50—Proteins
    • C12N2533/52—Fibronectin; Laminin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/50—Proteins
    • C12N2533/54—Collagen; Gelatin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/70—Polysaccharides
    • C12N2533/78—Cellulose
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2535/00—Supports or coatings for cell culture characterised by topography
EP17796855.9A 2016-05-11 2017-05-11 Hierarchisch strukturierte proteinmaterialien für dreidimensionale (3d) zelluläre unterstützungssysteme Pending EP3455348A4 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662334865P 2016-05-11 2016-05-11
PCT/US2017/032197 WO2017197138A1 (en) 2016-05-11 2017-05-11 Hierarchically structured protein materials for three dimensional (3d) cellular support systems

Publications (2)

Publication Number Publication Date
EP3455348A1 EP3455348A1 (de) 2019-03-20
EP3455348A4 true EP3455348A4 (de) 2019-12-18

Family

ID=60267433

Family Applications (1)

Application Number Title Priority Date Filing Date
EP17796855.9A Pending EP3455348A4 (de) 2016-05-11 2017-05-11 Hierarchisch strukturierte proteinmaterialien für dreidimensionale (3d) zelluläre unterstützungssysteme

Country Status (3)

Country Link
US (1) US11479753B2 (de)
EP (1) EP3455348A4 (de)
WO (1) WO2017197138A1 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022240655A1 (en) * 2021-05-10 2022-11-17 The Regents Of The University Of California Methods of using shaped particles in flow cytometers for assays on b cells and t cells
US20230357710A1 (en) * 2022-05-06 2023-11-09 The Regents Of The University Of Michigan Engineered fibrillar extracellular matrix networks for three-dimensional (3d) cellular support systems

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012094611A1 (en) * 2011-01-06 2012-07-12 Humacyte Tissue-engineered constructs
WO2013040078A2 (en) * 2011-09-12 2013-03-21 Organovo, Inc. Engineered tissues for in vitro research uses, arrays thereof, and methods of making the same

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FR2234311B1 (de) 1973-06-21 1976-04-30 Air Liquide
EP0097907A3 (de) 1982-06-25 1985-01-09 Flow General, Inc. Mikroträger für Zellkultur
US5266480A (en) 1986-04-18 1993-11-30 Advanced Tissue Sciences, Inc. Three-dimensional skin culture system
US20060252981A1 (en) * 2002-12-05 2006-11-09 Hikaru Matsuda Biocompatible implant and use of the same
US8039258B2 (en) 2004-09-28 2011-10-18 Ethicon, Inc. Tissue-engineering scaffolds containing self-assembled-peptide hydrogels
US20090148486A1 (en) * 2005-04-28 2009-06-11 Helen Lu Compositions and methods for treating pulp inflammations caused by infection or trauma
CN101245313A (zh) 2007-02-13 2008-08-20 刘青 三维细胞培养插入件、其制造方法、成套用具及用途
US8574906B2 (en) 2007-08-09 2013-11-05 Corning Incorporated Cell culture surfaces having hydrogel supported proteins
WO2009117721A1 (en) 2008-03-21 2009-09-24 3D Biotek, Llc Hybrid biomedical device fabricated from biomaterials and coated with a cell culture derived ecm coating
JP5840054B2 (ja) 2011-03-28 2016-01-06 地方独立行政法人東京都立産業技術研究センター 複合材料、培養容器及び細胞培養器用仕切り部材
WO2015005349A1 (ja) 2013-07-09 2015-01-15 国立大学法人東京大学 細胞培養支持体、細胞培養装置、細胞培養キット、及び細胞シート
US9737590B2 (en) * 2013-07-31 2017-08-22 Vivex Biomedical, Inc. Self-assembly of collagen fibers from dermis, fascia and tendon for tissue augmentation and coverage of wounds and burns
WO2016042211A1 (en) * 2014-09-17 2016-03-24 University Of Helsinki Implantable materials and uses thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012094611A1 (en) * 2011-01-06 2012-07-12 Humacyte Tissue-engineered constructs
WO2013040078A2 (en) * 2011-09-12 2013-03-21 Organovo, Inc. Engineered tissues for in vitro research uses, arrays thereof, and methods of making the same

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
CAPULLI A K ET AL: "Fibrous scaffolds for building hearts and heart parts", ADVANCED DRUG DELIVERY REVIEWS, ELSEVIER, AMSTERDAM, NL, vol. 96, 4 December 2015 (2015-12-04), pages 83 - 102, XP029372142, ISSN: 0169-409X, DOI: 10.1016/J.ADDR.2015.11.020 *
LI D ET AL: "Electrospinning Nanofibers as Uniaxially Aligned Arrays and Layer-by-Layer Stacked Films", ADVANCED MATERIALS, WILEY-VCH GERMANY, DE, vol. 16, no. 4, 17 February 2004 (2004-02-17), pages 361 - 366, XP002492421, ISSN: 0935-9648, DOI: 10.1002/ADMA.200306226 *
SABATER I SERRA ROSER ET AL: "Role of chemical crosslinking in material-driven assembly of fibronectin (nano)networks: 2D surfaces and 3D scaffolds", COLLOIDS AND SURFACES. B, BIOINTERFACES, ELSEVIER, AMSTERDAM, NL, vol. 148, 31 January 2016 (2016-01-31), pages 324 - 332, XP029790306, ISSN: 0927-7765, DOI: 10.1016/J.COLSURFB.2016.08.044 *
See also references of WO2017197138A1 *

Also Published As

Publication number Publication date
US11479753B2 (en) 2022-10-25
EP3455348A1 (de) 2019-03-20
WO2017197138A1 (en) 2017-11-16
US20190144818A1 (en) 2019-05-16

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