EP3325158A4 - Systèmes microfluidiques reconfigurables et dosages immunologiques multiplexés échelonnables - Google Patents

Systèmes microfluidiques reconfigurables et dosages immunologiques multiplexés échelonnables Download PDF

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Publication number
EP3325158A4
EP3325158A4 EP16830997.9A EP16830997A EP3325158A4 EP 3325158 A4 EP3325158 A4 EP 3325158A4 EP 16830997 A EP16830997 A EP 16830997A EP 3325158 A4 EP3325158 A4 EP 3325158A4
Authority
EP
European Patent Office
Prior art keywords
scalable
microfluidic systems
multiplexed immunoassays
reconfigurable microfluidic
reconfigurable
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP16830997.9A
Other languages
German (de)
English (en)
Other versions
EP3325158A1 (fr
Inventor
Hong Jiao
Erik C. Jensen
Homayun Mehrabani
Liran Yosef Haller
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hj Science & Technology Inc
Original Assignee
Hj Science & Technology Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US14/808,929 external-priority patent/US9956558B2/en
Priority claimed from US14/808,939 external-priority patent/US9733239B2/en
Priority claimed from US14/808,933 external-priority patent/US9956557B2/en
Application filed by Hj Science & Technology Inc filed Critical Hj Science & Technology Inc
Publication of EP3325158A1 publication Critical patent/EP3325158A1/fr
Publication of EP3325158A4 publication Critical patent/EP3325158A4/fr
Withdrawn legal-status Critical Current

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502746—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means for controlling flow resistance, e.g. flow controllers, baffles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/50273—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means or forces applied to move the fluids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/02—Adapting objects or devices to another
    • B01L2200/026—Fluid interfacing between devices or objects, e.g. connectors, inlet details
    • B01L2200/027—Fluid interfacing between devices or objects, e.g. connectors, inlet details for microfluidic devices
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0864—Configuration of multiple channels and/or chambers in a single devices comprising only one inlet and multiple receiving wells, e.g. for separation, splitting
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0867—Multiple inlets and one sample wells, e.g. mixing, dilution
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/087—Multiple sequential chambers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/16—Surface properties and coatings
    • B01L2300/161—Control and use of surface tension forces, e.g. hydrophobic, hydrophilic
    • B01L2300/165—Specific details about hydrophobic, oleophobic surfaces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0487—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/08—Regulating or influencing the flow resistance
    • B01L2400/084—Passive control of flow resistance
    • B01L2400/088—Passive control of flow resistance by specific surface properties
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502715—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
EP16830997.9A 2015-07-24 2016-06-29 Systèmes microfluidiques reconfigurables et dosages immunologiques multiplexés échelonnables Withdrawn EP3325158A4 (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US14/808,929 US9956558B2 (en) 2015-07-24 2015-07-24 Reconfigurable microfluidic systems: homogeneous assays
US14/808,939 US9733239B2 (en) 2015-07-24 2015-07-24 Reconfigurable microfluidic systems: scalable, multiplexed immunoassays
US14/808,933 US9956557B2 (en) 2015-07-24 2015-07-24 Reconfigurable microfluidic systems: microwell plate interface
PCT/US2016/040071 WO2017019241A1 (fr) 2015-07-24 2016-06-29 Systèmes microfluidiques reconfigurables et dosages immunologiques multiplexés échelonnables

Publications (2)

Publication Number Publication Date
EP3325158A1 EP3325158A1 (fr) 2018-05-30
EP3325158A4 true EP3325158A4 (fr) 2018-12-12

Family

ID=57885008

Family Applications (2)

Application Number Title Priority Date Filing Date
EP16830993.8A Pending EP3325157A4 (fr) 2015-07-24 2016-06-27 Systèmes microfluidiques reconfigurables : dosages homogènes
EP16830997.9A Withdrawn EP3325158A4 (fr) 2015-07-24 2016-06-29 Systèmes microfluidiques reconfigurables et dosages immunologiques multiplexés échelonnables

Family Applications Before (1)

Application Number Title Priority Date Filing Date
EP16830993.8A Pending EP3325157A4 (fr) 2015-07-24 2016-06-27 Systèmes microfluidiques reconfigurables : dosages homogènes

Country Status (4)

Country Link
EP (2) EP3325157A4 (fr)
CN (2) CN108290154B (fr)
CA (2) CA2992447C (fr)
WO (2) WO2017019221A1 (fr)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008103824A1 (fr) * 2007-02-23 2008-08-28 Chinese Academy Of Inspection And Quarantine (Caiq) Immunoessai à l'or lié à un anticorps par point amélioré en sensibilité pour la détection de virus
US20110120562A1 (en) * 2009-11-24 2011-05-26 Claros Diagnostics, Inc. Fluid mixing and delivery in microfluidic systems
US8772017B2 (en) * 2006-03-15 2014-07-08 Micronics, Inc. Integrated nucleic acid assays

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2399199A1 (fr) * 2000-02-23 2001-08-30 Ring-Ling Chien Systeme regulateur de pression de reservoirs multiples
ATE355128T1 (de) * 2002-09-06 2006-03-15 Epigem Ltd Modulares mikrofluidsystem
US7011793B2 (en) * 2003-05-15 2006-03-14 Kionix, Inc. Reconfigurable modular microfluidic system and method of fabrication
US7976795B2 (en) * 2006-01-19 2011-07-12 Rheonix, Inc. Microfluidic systems
CN102740976B (zh) * 2010-01-29 2016-04-20 精密公司 取样-应答微流体盒
US9829451B2 (en) * 2011-10-09 2017-11-28 Simon Fraser University Microfluidic reconfiguration device for multi-plexed sample analysis

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8772017B2 (en) * 2006-03-15 2014-07-08 Micronics, Inc. Integrated nucleic acid assays
WO2008103824A1 (fr) * 2007-02-23 2008-08-28 Chinese Academy Of Inspection And Quarantine (Caiq) Immunoessai à l'or lié à un anticorps par point amélioré en sensibilité pour la détection de virus
US20110120562A1 (en) * 2009-11-24 2011-05-26 Claros Diagnostics, Inc. Fluid mixing and delivery in microfluidic systems

Also Published As

Publication number Publication date
CN108290154B (zh) 2021-07-30
CA2992434C (fr) 2023-08-08
WO2017019241A1 (fr) 2017-02-02
EP3325157A4 (fr) 2018-12-12
WO2017019221A1 (fr) 2017-02-02
CN108290154A (zh) 2018-07-17
EP3325158A1 (fr) 2018-05-30
CA2992447C (fr) 2023-08-29
CA2992434A1 (fr) 2017-02-02
EP3325157A1 (fr) 2018-05-30
CA2992447A1 (fr) 2017-02-02
CN108290153A (zh) 2018-07-17

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