EP3291859A1 - Injecteur à usage unique comprenant une couche insonorisante - Google Patents

Injecteur à usage unique comprenant une couche insonorisante

Info

Publication number
EP3291859A1
EP3291859A1 EP15723858.5A EP15723858A EP3291859A1 EP 3291859 A1 EP3291859 A1 EP 3291859A1 EP 15723858 A EP15723858 A EP 15723858A EP 3291859 A1 EP3291859 A1 EP 3291859A1
Authority
EP
European Patent Office
Prior art keywords
piston
disposable injector
layer
housing
cylinder
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP15723858.5A
Other languages
German (de)
English (en)
Inventor
Thorsten Sichtermann
Uwe Wortmann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
LTS Lohmann Therapie Systeme AG
Original Assignee
LTS Lohmann Therapie Systeme AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by LTS Lohmann Therapie Systeme AG filed Critical LTS Lohmann Therapie Systeme AG
Publication of EP3291859A1 publication Critical patent/EP3291859A1/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M5/2033—Spring-loaded one-shot injectors with or without automatic needle insertion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31511—Piston or piston-rod constructions, e.g. connection of piston with piston-rod
    • A61M5/31513—Piston constructions to improve sealing or sliding
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M2005/2073—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically preventing premature release, e.g. by making use of a safety lock
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M2005/2086—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically having piston damping means, e.g. axially or rotationally acting retarders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M2005/3117—Means preventing contamination of the medicament compartment of a syringe
    • A61M2005/3118—Means preventing contamination of the medicament compartment of a syringe via the distal end of a syringe, i.e. syringe end for mounting a needle cannula
    • A61M2005/312—Means preventing contamination of the medicament compartment of a syringe via the distal end of a syringe, i.e. syringe end for mounting a needle cannula comprising sealing means, e.g. severable caps, to be removed prior to injection by, e.g. tearing or twisting
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M2005/3143—Damping means for syringe components executing relative movements, e.g. retarders or attenuators slowing down or timing syringe mechanisms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/02—General characteristics of the apparatus characterised by a particular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/42—Reducing noise

Definitions

  • the invention relates to a disposable injector with a housing, arranged in the housing, unlocked by means of a trip unit, spring-loaded
  • such a disposable injector is known. Triggering the disposable injector can scare the patient. The patient can flinch. This allows the disposable injector to slip away from the intended injection site.
  • the present invention is based on the problem of designing a disposable injector such that the patient is not frightened during the application.
  • a closed layer of an elastically deformable material at least partially surrounds the piston actuating ram and projects beyond it in the release direction
  • FIG. 1 disposable injector with closure cap
  • Figure 2 exploded view of the disposable injector of Figure i;
  • FIG. 3 shows a longitudinal section of the disposable injector of FIG. 1;
  • Figure 4 longitudinal section normal to Figure 3;
  • FIG. 5 cross section of the disposable injector above the
  • FIG. 6 disposable injector after release
  • FIG. 7 disposable injector with emptied cylinder-piston unit
  • Figure 8 sectional view of a disposable injector with inserted
  • FIG. 10 disposable injector with emptied cylinder-piston unit
  • FIG. 11 disposable injector with inserted insulating sleeve
  • FIG. 12 disposable injector from FIG. 11 with the ejected one
  • FIG. 13 disposable injector with external insulating layer
  • Figure 14 piston actuating plunger made of composite material.
  • Figures 1 - 7 show a disposable or disposable injector (4).
  • Such injectors (4) are used for the single introduction of an injection solution (1) or a solvent stored in a cylinder-piston unit (100) into the skin of a patient.
  • FIG. 1 shows a dimetric view of the disposable injector (4). He has a two-part release sleeve (82), here an upper shell (220) and a
  • Lower shell (230) includes.
  • This cross-sectionally polygonal release sleeve (82) has an at least approximately regular, triangular-like cross-section, cf. FIG. 5.
  • the cross-sectional area in the rear region of the disposable injector (4) facing away from the injection site is 70% of the cross-sectional area in the front, the injection location facing the disposable injector (4).
  • Cross-sectional area is, seen from the rear, in the third quarter of the length of the disposable injector (4).
  • the triggering of the disposable injector (4) is prevented by means of a safety slide (87). This can be removable for protection or he can in
  • the cylinder-piston unit (100) has at its front end an outlet opening (106).
  • FIG. 2 is an exploded view and in FIGS. 3 and 4
  • FIGS. 3 and 4 Longitudinal sections of the unactuated disposable injector (4) shown.
  • the upper end of the disposable injector (4) in FIGS. 3 and 4 corresponds to the rear end in FIG.
  • the disposable injector (4) comprises a tubular housing (10), in which a spring energy storage (50) and a piston actuation plunger (60) are arranged.
  • the housing (10) has inwardly projecting spring hooks (42).
  • the spring hooks (42) in the illustrations of Figs. 3 and 4 the e.g. Pre-filled cylinder-piston unit (100) inserted and locked.
  • the housing (10) has a substantially cylindrical inner contour. In the rear area, an internal thread (11) is arranged. In this sits a support screw (12) with a hexagonal section (13).
  • the outer contour of the housing (10) has a cylindrical basic shape with a flattening (14). In the region of the flattening (14) is a support rod (21) on the housing (10). The opposite side of the
  • Housing (10) has a in the longitudinal direction (5) of the disposable injector (4) oriented guide rib (15).
  • the piston actuating punch (60) has a cylindrical guide pin (62), a punch plate (73) and a piston slide (76).
  • the guide pin (62) carries and guides the spring energy store (50), which is designed here as a helical compression spring (50).
  • the upper end of the helical compression spring (50) in FIGS. 3 and 4 is supported on the support screw (12) via a washer (38) and a clamping limb (25) of the support rod (21).
  • the guide pin (62) has circular-segment-shaped recesses (66) oriented in the radial direction.
  • the punch plate (73) of the piston actuating punch (60) is disc-shaped and aligned normal to the central longitudinal axis (7) of the disposable injector (4). He has one of the helical compression spring (50) facing away, conically shaped collar surface (75). The point angle of the imaginary cone of the collar surface (75) is for example 160 degrees. At this collar surface (75) is located on a support disc (160).
  • Support disc (160) is a perforated disc with a splined hub profile. It is frustoconical in the side view.
  • the support disk (160) is made, for example, of a metallic material, e.g. an austenitic steel. In the illustration of Figure 3, it is secured by means of a Umgriffshakens (26) of the support rod (21) in position.
  • the rod-like piston slide (76) has an at least approximately cylindrical shape in the embodiment. For attaching an assembly tool, it has in the longitudinal direction of the disposable injector (4) aligned key surfaces (77).
  • support rod (21) is strip-shaped in the embodiment.
  • it is made of austenitic spring steel. Over its length he has a e.g. constant, rectangular cross-section. Its two ends are bent inwards.
  • the upper end in Figure 3 forms the clamping leg (25) which, with the longitudinally oriented main leg (27), makes an angle of e.g. Includes 90 degrees.
  • Support rod (21) forms the Umgriffshaken (26). It closes with the main leg (27) an angle which by the inclination angle of the collar surface (75) to a
  • the clamping limb (25) projects through an upper, slot-shaped housing opening (16) into the interior space (17) of the housing (10).
  • the Umgriffshaken (26) protrudes through a lower, housing opening (18) with a rectangular cross-section into the housing (10).
  • a plurality of support rods (21). can be connected to each other in the region of the clamping leg (25).
  • the cylinder-piston unit (100) comprises, for example, a transparent cylinder (101) in which, according to the representation of FIG.
  • a piston (111) is seated in the rear position.
  • the piston (111) by a gap (141) spaced from the piston actuating ram (60).
  • the length of the gap (141) in the longitudinal direction (5) of the disposable injector (4) is for example a few
  • Millimeters e.g. the distance is less than ten millimeters.
  • Outlet opening (106) which is designed here as a short, cylindrical, nozzle-like bore (106). This outlet opening (106) is closed before use of the disposable injector (4), for example by means of a closure cap (120). At her
  • Peripheral surface (122) has these a corrugation (123) in order to avoid slippage of the fingers.
  • a circlip (250) sits on the spring hook (42) when the cylinder-piston unit (100) is mounted.
  • the retaining ring (250) has in
  • Embodiment a circular base. Its outer diameter is smaller than the inner diameter of the trigger element (82) and smaller than that
  • a trigger ring On the housing (10) sits a trigger ring (190). Its lateral surface has an upper cylindrical portion (192) and a lower portion (191). The lower portion (191) is partially cylindrical and partially frusto-conical.
  • the cylindrical inner wall (193) in the basic form has an anti-rotation groove (194) oriented in the axial direction (5) on one side.
  • an obliquely formed contact surface (195) On the opposite side of an obliquely formed contact surface (195) is formed. This contact surface (195) is for example at an angle of 20 degrees to
  • the two shells (220, 230) of the release sleeve (82) each have on their inside reinforcing ribs (221 - 227; 231 - 237).
  • These transverse ribs (221-227, 231-237) are oriented normal to the longitudinal direction (5) of the disposable injector (4).
  • the rear reinforcing ribs (223 - 227; 232 - 237) each have two parts, between which a groove (239) is arranged.
  • the foremost reinforcing ribs (221, 222, 231) are each designed to be interruption-free.
  • Lower shell (230) are connected to each other by means of a plurality of pin connections (228, 238).
  • a layer (140) of an elastically deformable material is arranged in the release sleeve (82) .
  • the release sleeve (82) forms the support area (135) for this layer (140), which is e.g. may consist of bitumen, foam, foam rubber or felt.
  • the modulus of elasticity of this material is less than half of the
  • the layer (140) is glued there, latched or held in position by means of connecting elements.
  • the layer (140) may be connected to the component carrying it by means of a chemical or physical connection.
  • the layer (140) in the radial direction circumferentially at least in the region of the front end of the
  • Piston actuating punch (60) formed. In the release direction (6), the layer (140) projects beyond the front end of the piston-actuating punch (60).
  • the thickness of the layer (140) corresponds at least to the thickness of the support member (135). It may, for example, up to ten times the thickness of the support member (135)
  • the portion (153, 147) which is disposed between the second transverse rib (222; 232) and the third transverse rib (223; 233) has, for example, an inner diameter 15% larger than the remaining portions (145, 146; 151, 152 , 154-157) of the layer (140).
  • Clamping leg (25) is applied or pressed against this.
  • Piston actuating punch (60) is pressed in.
  • Piston actuating punch (60) is pressed in.
  • Tensioned compression spring (50) For example, the housing (10) is held on a retaining ring (211). The Umgrlffshaken (26) of the support rod (21) is inserted into the rectangular recess (18) and to the underside (161) of
  • Spring energy storage (50) In the lower region of the disposable injector (4), the securing ring (250) is slid onto the spring hooks (42) until, for example, it bears against the retaining ring (211). Now, for example, the pre-filled cylinder-piston unit (100) can be inserted into the housing (10) and locked in this. The locking ring (250) is pulled forward, thus ensuring the position of the cylinder-piston unit (100).
  • the shell-shaped sections (145-147) of the layer (140) of elastically deformable material are inserted into the upper shell (220) and fixed.
  • Lower shell (230), the portions (151 - 157) of the layer (140) are inserted and fixed.
  • the material projects slightly beyond the parting plane between the upper shell (220) and the lower shell (230).
  • the pre-assembly with the housing (10) and the cylinder-piston unit (100) is inserted for example in the lower shell (230).
  • the rib (15) of the housing (10) in the longitudinal groove (239) of the lower shell (230) is centered.
  • Release ring (190) lies between the transverse ribs (222, 223, 232, 233).
  • the head of the support screw (12) protrudes beyond the rearmost transverse rib (227; 237).
  • the cap (120) is outside the trigger sleeve (82). After inserting the securing element (87) into the slot (241) of the lower shell (230), this clamps e.g. between the support screw (12) and the sleeve (82).
  • an additional compression spring between the support screw (12) and the sleeve (82) increase the resistance to accidental release.
  • the U-shaped bracket can be removed.
  • the upper shell (220) is placed on the lower shell (230) and, e.g. secured by gluing, latching, etc. Now you can
  • tamper-evident closure e.g. a banderole
  • additional tamper-evident closure e.g. a banderole
  • the trigger sleeve (82) and the cap (120) are attached.
  • the tamper-evident closure is first removed. After removing the cap (120), the tamper-evident closure is first removed. After removing the cap (120), the tamper-evident closure is first removed. After removing the cap (120), the
  • Retaining element (87) are pulled out.
  • the disposable injector (4) is now ready for use and is, for example, placed on the skin of the patient.
  • the end face (103) of the cylinder-piston unit (100) adheres to the skin of the patient.
  • the release sleeve (82) is moved to the vome, ie in the direction of the skin of the patient.
  • the release sleeve (82) in this case shifts the release ring (190) relative to the housing (10) in the sectional views of Figures 3, 4, 6 and 7 down.
  • FIG. 6 shows this non-static state.
  • the spring energy store (50) pushes the punch plate (73) forward.
  • the thrust washer (160) displaces the Umgriffshaken (26) of the support rod (21).
  • the support rod (21) slides outward along the sliding plate (196), thereby completely releasing the piston-actuating ram (60).
  • the piston actuating punch (60) charged by the relaxing spring energy store (50), jumps forward or down.
  • the piston slide (76) strikes the piston (111) and pushes it forward.
  • the injection solution (1) stored in the cylinder (101) is replaced by the
  • FIG. 7 shows the disposable injector (4) after triggering.
  • the sound produced when the piston-actuating ram (60) strikes the piston (111) propagates as structure-borne noise as well as airborne sound in all directions. It strikes the layer (140) of elastically deformable material. This material insulates the sound propagation so that neither the operator nor the patient is startled by the impact and move the disposable injector (4). As a result, during the injection, the complete introduction of the injection solution into the body of the patient is ensured.
  • the sound insulation layer (140) shown in FIGS. 1-7 also surrounds the sound insulation layer 140
  • FIGS. 8-10 show a further design of a disposable or
  • FIG. 8 shows the disposable injector (4) after insertion of the cylinder-piston unit (100).
  • FIG. 9 shows the non-static state when the disposable injector (4) is triggered.
  • FIG. 10 shows the disposable injector (4) after the application, ie after the solution (1) has been dispensed.
  • the disposable injector (4) of this embodiment comprises a pot-shaped
  • housing (10) with an overhead floor (39).
  • the spring energy store (50) e.g. a helical compression spring (50) is arranged, which is supported on the bottom (39) of the housing (10).
  • the helical compression spring (50) acts on the piston actuating ram (60). This one also leads in this
  • Embodiment by means of e.g. cylindrical guide pin (62) in the figure 8 lower end of the helical compression spring (50).
  • the piston actuating punch (60) further comprises the punch plate (73) and the e.g. cylindrically shaped piston slide (76).
  • the stamping plate (73) has a conically shaped collar surface (75). With this collar surface (75), the piston-actuating ram (60) is supported on elastically deformable support rods (21) of the housing (10). It is also conceivable to use only one support rod.
  • the support rods (21) are flexible, cantilevered rods in this embodiment, the lower end, for example, with the housing (10) is connected. At their upper end they have outwardly projecting cams (22). These have an overhead support surface (23) on which the stamping plate (73) rests. The outwardly facing surface (24) is a contact surface (24).
  • the lower end of the spool (76) is a few millimeters above the
  • the housing (10) shown in FIGS. 8-10 also has inwardly projecting spring hooks (42) into which the cylinder-piston unit (100), for example prefilled, is inserted. is inserted and locked.
  • the housing (10) shown in FIGS. 8-10 also has inwardly projecting spring hooks (42) into which the cylinder-piston unit (100), for example prefilled, is inserted. is inserted and locked.
  • the housing (10) shown in FIGS. 8-10 also has inwardly projecting spring hooks (42) into which the cylinder-piston unit (100), for example prefilled, is inserted. is inserted and locked.
  • the housing (10) shown in FIGS. 8-10 also has inwardly projecting spring hooks (42) into which the cylinder-piston unit (100), for example prefilled, is inserted. is inserted and locked.
  • the housing (10) shown in FIGS. 8-10 also has inwardly projecting spring hooks (42) into which the cylinder-piston unit (100), for example prefilled, is
  • Piston (111) in its rear position.
  • the piston actuating punch (60) and the piston (111) are spaced from each other by a gap (141).
  • the upper end of the piston (111) can also be above or below the upper edge plane of the cylinder (101).
  • the outlet opening (106) sealed prior to the use of the disposable injector (4) is designed as in connection with the first
  • the disposable injector (4) further comprises a triggering unit (80).
  • this comprises a tubular-shaped release element (82).
  • Outer wall (88) of the trigger element (82) has, for example, in the lower area circumferential handle webs (89). In the upper area, the triggering element (82) is reinforced by means of longitudinal ribs (131).
  • the inner wall (132) of the trigger element (82) has at the top of a widening (83) and one above! laying, circumferential inner ring (133). In the assembled state shown in FIG. 8, this widening (83) lies above the support rods (21). Below the widening (83) are the cams (22) with their
  • Supporting region (135) is arranged a circumferential layer (140) of an elastically deformable material.
  • the structure of the layer (140) corresponds to the structure of the layer (140) mentioned in connection with the first exemplary embodiment.
  • the layer (140) may then be, for example
  • the inner wall (135) of the trigger element (82) can be formed below the widening (83) in a cylindrical shape without a depression (136).
  • the support area (135) is also in this case, the inner wall (132) of the
  • Triggering element (82) on which the layer material (140) is attached On which the layer material (140) is attached.
  • a closure cap (120) is shown in the illustration of FIG. This is latched, for example, with the housing (10) and closes the outlet opening (106) of the cylinder-piston unit (100).
  • the disposable injector (4) is additionally equipped with one, one
  • the housing (10), the trigger element (82), the piston actuation plunger (60) of the cylinder (101), the piston (111) and the closure cap (120) are made of plastics, for example. These can be impact-resistant thermosets or thermoplastics. The said parts may be normal to their longitudinal direction (5) an annular,
  • the piston actuating punch (60) is inserted together with the spring (50) in the housing (10) and the trigger element (82) pushed over it.
  • the cap (120) is placed.
  • the tamper-evident closure (90) is attached.
  • the layer (140) of elastically deformable material surrounds the lower portion of the piston actuating punch (60), the gap (141) and the upper portion of the piston (111) and the cylinder (101) in the radial direction.
  • the spool (76) abruptly hits the piston (111) of the cylinder-piston unit (100).
  • sound waves are emitted, which propagate from the contact point of the spool (76) and the piston (111). They penetrate the columns of the housing (10) located between the support rods (21) and strike the elastically deformable material (140). Here they are insulated and do not reach or only to a small extent in the environment.
  • the disposable injector (4) maintains its position so that the drug solution (1) can be introduced lossless in the skin of the patient.
  • Piston actuating punch (60) moved further forward and pushes the
  • Solution (1) is pushed out of the Zyfinder piston unit (100) through the outlet opening (106), cf. FIG. 10.
  • the layer (140) of elastically deformable material can also be arranged on the housing (10). So it is conceivable, this closed layer (140) on the
  • the layer (140) may have beads or warps, so that the movement of the layer (140).
  • Supporting rods (21) is not obstructed.
  • the disposable injector (4) can be disposed of.
  • the Einmaiinjektor shown here (4) is executed without a needle. But it is also conceivable, a
  • FIGS. 11 and 12 show a disposable injector (4), which has a similar construction to the disposable injector (4) shown in FIGS. 8-10.
  • Piston slide (76) and is forward, so in the release direction (6) on this over.
  • the upper end of the piston (111) is located
  • the insertion sleeve (142) comprises a support body (143) and a closed
  • Layer (140) elastically deformable materials The latter is inward. But it is also conceivable to arrange the layer (140) on the lateral surface of the support body (143). With an upper inner ring (144), the insert sleeve (142) abuts on the piston slide (76) in this exemplary embodiment and is inserted along the
  • the spool (76) may have a waist into which the inner ring (144) engages during assembly. The inner ring (144) with the insert sleeve (142) is then slidable between the two ends of the waist.
  • Piston slide (76) pushed. It can e.g. frictionally engaged
  • Piston slide (76) may be formed. Also in this embodiment, after the insertion of the cylinder-piston unit (100), the cap (120) is placed and the tamper-evident closure (90) attached.
  • Support body (143) conduct the sound and reflect by means of its inner wall. However, the insulating layer surrounding the support body (143) hinders the sound from leaking into the environment of the disposable injector (4).
  • the application of the injection solution (1) takes place as described above (n of FIG. 12 is the empty one)
  • FIG. 13 shows a disposable injector (4) with a triggering sleeve (82) on whose
  • This closed layer (140) engages around the piston actuating punch (60), the cylinder-piston unit (100) and the cams (22).
  • the layer (140) thus attenuates both the noise produced by jumping the cams (22) into the widening (83) and the noise produced when the piston-actuating punch (76) strikes the piston (111).
  • an outer sleeve (86) surrounds the release sleeve (82) and the Dämmmaterial für (140). It is also conceivable that
  • a piston actuating punch (60) is shown, which consists of a
  • the material of the cylindrical core (63) is for example an austenitic steel. Its modulus of elasticity is e.g. at
  • the material surrounding the core (63) is in this embodiment a carbon fiber reinforced plastic with a
  • a thermoset or a thermoplastic material is conceivable.
  • the length of the core (63) in the longitudinal direction of the disposable injector (60) corresponds in this embodiment, the length of the spool (76) and the length of the punch plate (73).
  • the core (63) may have a funnel-shaped or mushroom-shaped approach. The upper end of the funnel then points in the direction of the spring rest (65).
  • the diameter of the cylindrically shaped core (63) is here e.g. one third of the diameter of the piston valve (76).
  • In mounted disposable injector (4) is to the spool (76) and the
  • the resulting structure-borne noise is insulated by means of the shell (64).
  • the airborne sound produced upon impact is insulated by means of the closed layer (140) of the elastically deformable material.

Landscapes

  • Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

L'invention concerne un injecteur à usage unique comprenant un boîtier, un poussoir d'actionnement de piston agencé dans le boîtier, sollicité par un ressort et déverrouillable au moyen d'une unité de déclenchement, ainsi qu'une unité cylindre-piston comprenant un cylindre et un piston espacé du poussoir d'actionnement de piston. Une couche fermée (140) constituée d'un matériau élastiquement déformable entoure au moins partiellement le poussoir d'actionnement de piston et fait saillie par rapport à celui-ci dans la direction de déclenchement. La présente invention permet de concevoir un injecteur à usage unique dont l'utilisation n'effraie pas le patient.
EP15723858.5A 2015-05-04 2015-05-04 Injecteur à usage unique comprenant une couche insonorisante Withdrawn EP3291859A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/EP2015/059693 WO2016177390A1 (fr) 2015-05-04 2015-05-04 Injecteur à usage unique comprenant une couche insonorisante

Publications (1)

Publication Number Publication Date
EP3291859A1 true EP3291859A1 (fr) 2018-03-14

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EP15723858.5A Withdrawn EP3291859A1 (fr) 2015-05-04 2015-05-04 Injecteur à usage unique comprenant une couche insonorisante

Country Status (7)

Country Link
US (1) US10413669B2 (fr)
EP (1) EP3291859A1 (fr)
JP (1) JP6634093B2 (fr)
CN (1) CN107405452B (fr)
BR (1) BR112017022950A2 (fr)
CA (1) CA2973395A1 (fr)
WO (1) WO2016177390A1 (fr)

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Publication number Priority date Publication date Assignee Title
WO2020209315A1 (fr) * 2019-04-09 2020-10-15 株式会社根本杏林堂 Injecteur de fluide médical et dispositif d'injection de fluide médical le comprenant
CN112603308B (zh) * 2020-12-17 2022-10-04 重庆市公共卫生医疗救治中心 一种防止艾滋病交叉感染的抽血装置

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US8591463B1 (en) * 2013-03-08 2013-11-26 Teva Pharmaceutical Industries Ltd. Re-useable injector device for syringe

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RU2179864C2 (ru) * 1993-07-31 2002-02-27 Вестон Медикал Лимитед Безыгольный инъектор
GB9605690D0 (en) * 1996-03-19 1996-05-22 Oxford Biosciences Ltd Particle delivery
US20030105430A1 (en) * 2001-11-30 2003-06-05 Elan Pharma International Limited Wil House Automatic injector
JP2006522658A (ja) * 2003-04-08 2006-10-05 メドラッド インコーポレーテッド 流体運搬システム、流体運搬装置、及び危険性流体を搬送する方法
WO2007002052A2 (fr) * 2005-06-21 2007-01-04 Eli Lilly And Company Appareil et procede d'injection de medicament
WO2007002053A2 (fr) * 2005-06-21 2007-01-04 Eli Lilly And Company Dispositif d'administration de medicament muni d'une aiguille a insertion d'aiguille a declenchement automatique et a injection de medicament a commande manuelle
GB2438592B (en) * 2006-06-01 2011-04-06 Cilag Gmbh Int Injection device
US8132111B2 (en) 2007-01-25 2012-03-06 Samuel Pierce Baron Virtual social interactions
DE102007031714A1 (de) 2007-07-06 2009-01-08 Lts Lohmann Therapie-Systeme Ag Einweginjektor mit mindestens einem Druckstab und einer Verschlusskappe
DE102007031630B3 (de) 2007-07-06 2008-12-24 Lts Lohmann Therapie-Systeme Ag Einweginjektor mit mindestens einem Stützstab
DE102008063519A1 (de) * 2008-12-18 2010-07-01 Lts Lohmann Therapie-Systeme Ag Einmalinjektor mit einem biegeelastischen Metallgehäuse
JP2014525783A (ja) * 2011-07-15 2014-10-02 アンタレス・ファーマ・インコーポレーテッド カム付ラムアセンブリを備える注射器
GB2506918A (en) * 2012-10-12 2014-04-16 Cambridge Consultants Injector device

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US8591463B1 (en) * 2013-03-08 2013-11-26 Teva Pharmaceutical Industries Ltd. Re-useable injector device for syringe

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Title
See also references of WO2016177390A1 *

Also Published As

Publication number Publication date
BR112017022950A2 (pt) 2018-07-17
US10413669B2 (en) 2019-09-17
WO2016177390A1 (fr) 2016-11-10
CN107405452B (zh) 2020-10-23
JP6634093B2 (ja) 2020-01-22
CN107405452A (zh) 2017-11-28
JP2018514318A (ja) 2018-06-07
CA2973395A1 (fr) 2016-11-10
US20180021516A1 (en) 2018-01-25

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