EP3213076A1 - Rekombinante borreliaproteine und verfahren zur verwendung davon - Google Patents
Rekombinante borreliaproteine und verfahren zur verwendung davonInfo
- Publication number
- EP3213076A1 EP3213076A1 EP15782207.3A EP15782207A EP3213076A1 EP 3213076 A1 EP3213076 A1 EP 3213076A1 EP 15782207 A EP15782207 A EP 15782207A EP 3213076 A1 EP3213076 A1 EP 3213076A1
- Authority
- EP
- European Patent Office
- Prior art keywords
- borrelia
- antigens
- recombinant
- proteins
- antibodies
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 108090000623 proteins and genes Proteins 0.000 title claims abstract description 155
- 208000016604 Lyme disease Diseases 0.000 title claims abstract description 143
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- 241000589968 Borrelia Species 0.000 title claims description 83
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/20—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Spirochaetales (O), e.g. Treponema, Leptospira
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6854—Immunoglobulins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/195—Assays involving biological materials from specific organisms or of a specific nature from bacteria
- G01N2333/20—Assays involving biological materials from specific organisms or of a specific nature from bacteria from Spirochaetales (O), e.g. Treponema, Leptospira
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/26—Infectious diseases, e.g. generalised sepsis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physics & Mathematics (AREA)
- Urology & Nephrology (AREA)
- Medicinal Chemistry (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Cell Biology (AREA)
- Plant Pathology (AREA)
- Gastroenterology & Hepatology (AREA)
- Food Science & Technology (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Peptides Or Proteins (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201462060867P | 2014-10-07 | 2014-10-07 | |
US201462076059P | 2014-11-06 | 2014-11-06 | |
PCT/US2015/054303 WO2016057562A1 (en) | 2014-10-07 | 2015-10-06 | Recombinant borrelia proteins and methods of use thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
EP3213076A1 true EP3213076A1 (de) | 2017-09-06 |
Family
ID=54337437
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP15782207.3A Withdrawn EP3213076A1 (de) | 2014-10-07 | 2015-10-06 | Rekombinante borreliaproteine und verfahren zur verwendung davon |
Country Status (6)
Country | Link |
---|---|
EP (1) | EP3213076A1 (de) |
JP (1) | JP2017531657A (de) |
AU (1) | AU2015328255A1 (de) |
CA (1) | CA2963643A1 (de) |
HK (1) | HK1244534A1 (de) |
WO (1) | WO2016057562A1 (de) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2017062535A2 (en) | 2015-10-06 | 2017-04-13 | Bio-Rad Laboratories, Inc. | Borrelia immunoassays and materials therefor |
WO2018017998A1 (en) | 2016-07-22 | 2018-01-25 | The Research Foundation For The State University Of New York | Recombinant borrelia proteins and methods of use thereof |
US10718767B2 (en) | 2018-03-09 | 2020-07-21 | Id-Fish Technology, Inc. | Species specific antigen sequences for tick-borne relapsing fever (TBRF) and methods of use |
US20220034880A1 (en) * | 2018-10-01 | 2022-02-03 | The Board Of Trustees Of The Leland Stanford Junior University | High specificity and sensitivity immunosorbent diagnostic assays with simultaneous resolution of multiple antibody isotypes |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU8127494A (en) * | 1993-11-01 | 1995-05-23 | Associated Universities, Inc. | Chimeric proteins comprising borrelia polypeptides: uses therefor |
US6248562B1 (en) | 1993-11-01 | 2001-06-19 | Research Foundation State University Of New York | Chimeric proteins comprising borrelia polypeptides and uses therefor |
US7008625B2 (en) | 1993-11-01 | 2006-03-07 | Research Foundation Of The State University Of New York | Recombinant constructs of Borrelia burgdorferi |
US6251405B1 (en) | 1995-06-07 | 2001-06-26 | Connaught Laboratories, Inc. | Immunological combination compositions and methods |
AU5751000A (en) | 1999-06-18 | 2001-01-09 | Brook Biotechnologies, Inc. | Groups of borrelia burgdorferi and borrelia afzelii that cause lyme disease in humans |
PT1311682E (pt) * | 2000-08-18 | 2008-03-11 | Brookhaven Sciences Ass Llc | Construcões recombinantes de borrelia burgdorferi |
-
2015
- 2015-10-06 JP JP2017518430A patent/JP2017531657A/ja active Pending
- 2015-10-06 EP EP15782207.3A patent/EP3213076A1/de not_active Withdrawn
- 2015-10-06 CA CA2963643A patent/CA2963643A1/en not_active Abandoned
- 2015-10-06 AU AU2015328255A patent/AU2015328255A1/en not_active Abandoned
- 2015-10-06 WO PCT/US2015/054303 patent/WO2016057562A1/en active Application Filing
-
2018
- 2018-03-06 HK HK18103163.5A patent/HK1244534A1/zh unknown
Non-Patent Citations (2)
Title |
---|
None * |
See also references of WO2016057562A1 * |
Also Published As
Publication number | Publication date |
---|---|
JP2017531657A (ja) | 2017-10-26 |
CA2963643A1 (en) | 2016-04-14 |
AU2015328255A1 (en) | 2017-04-27 |
HK1244534A1 (zh) | 2018-08-10 |
WO2016057562A1 (en) | 2016-04-14 |
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