EP3213076A1 - Rekombinante borreliaproteine und verfahren zur verwendung davon - Google Patents

Rekombinante borreliaproteine und verfahren zur verwendung davon

Info

Publication number
EP3213076A1
EP3213076A1 EP15782207.3A EP15782207A EP3213076A1 EP 3213076 A1 EP3213076 A1 EP 3213076A1 EP 15782207 A EP15782207 A EP 15782207A EP 3213076 A1 EP3213076 A1 EP 3213076A1
Authority
EP
European Patent Office
Prior art keywords
borrelia
antigens
recombinant
proteins
antibodies
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP15782207.3A
Other languages
English (en)
French (fr)
Inventor
Benjamin J. Luft
John F. Bruno
Yun Xu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Research Foundation of State University of New York
Original Assignee
Research Foundation of State University of New York
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Research Foundation of State University of New York filed Critical Research Foundation of State University of New York
Publication of EP3213076A1 publication Critical patent/EP3213076A1/de
Withdrawn legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62DNA sequences coding for fusion proteins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/20Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Spirochaetales (O), e.g. Treponema, Leptospira
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854Immunoglobulins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/195Assays involving biological materials from specific organisms or of a specific nature from bacteria
    • G01N2333/20Assays involving biological materials from specific organisms or of a specific nature from bacteria from Spirochaetales (O), e.g. Treponema, Leptospira
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/26Infectious diseases, e.g. generalised sepsis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physics & Mathematics (AREA)
  • Urology & Nephrology (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Plant Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Food Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
EP15782207.3A 2014-10-07 2015-10-06 Rekombinante borreliaproteine und verfahren zur verwendung davon Withdrawn EP3213076A1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462060867P 2014-10-07 2014-10-07
US201462076059P 2014-11-06 2014-11-06
PCT/US2015/054303 WO2016057562A1 (en) 2014-10-07 2015-10-06 Recombinant borrelia proteins and methods of use thereof

Publications (1)

Publication Number Publication Date
EP3213076A1 true EP3213076A1 (de) 2017-09-06

Family

ID=54337437

Family Applications (1)

Application Number Title Priority Date Filing Date
EP15782207.3A Withdrawn EP3213076A1 (de) 2014-10-07 2015-10-06 Rekombinante borreliaproteine und verfahren zur verwendung davon

Country Status (6)

Country Link
EP (1) EP3213076A1 (de)
JP (1) JP2017531657A (de)
AU (1) AU2015328255A1 (de)
CA (1) CA2963643A1 (de)
HK (1) HK1244534A1 (de)
WO (1) WO2016057562A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017062535A2 (en) 2015-10-06 2017-04-13 Bio-Rad Laboratories, Inc. Borrelia immunoassays and materials therefor
WO2018017998A1 (en) 2016-07-22 2018-01-25 The Research Foundation For The State University Of New York Recombinant borrelia proteins and methods of use thereof
US10718767B2 (en) 2018-03-09 2020-07-21 Id-Fish Technology, Inc. Species specific antigen sequences for tick-borne relapsing fever (TBRF) and methods of use
US20220034880A1 (en) * 2018-10-01 2022-02-03 The Board Of Trustees Of The Leland Stanford Junior University High specificity and sensitivity immunosorbent diagnostic assays with simultaneous resolution of multiple antibody isotypes

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU8127494A (en) * 1993-11-01 1995-05-23 Associated Universities, Inc. Chimeric proteins comprising borrelia polypeptides: uses therefor
US6248562B1 (en) 1993-11-01 2001-06-19 Research Foundation State University Of New York Chimeric proteins comprising borrelia polypeptides and uses therefor
US7008625B2 (en) 1993-11-01 2006-03-07 Research Foundation Of The State University Of New York Recombinant constructs of Borrelia burgdorferi
US6251405B1 (en) 1995-06-07 2001-06-26 Connaught Laboratories, Inc. Immunological combination compositions and methods
AU5751000A (en) 1999-06-18 2001-01-09 Brook Biotechnologies, Inc. Groups of borrelia burgdorferi and borrelia afzelii that cause lyme disease in humans
PT1311682E (pt) * 2000-08-18 2008-03-11 Brookhaven Sciences Ass Llc Construcões recombinantes de borrelia burgdorferi

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
None *
See also references of WO2016057562A1 *

Also Published As

Publication number Publication date
JP2017531657A (ja) 2017-10-26
CA2963643A1 (en) 2016-04-14
AU2015328255A1 (en) 2017-04-27
HK1244534A1 (zh) 2018-08-10
WO2016057562A1 (en) 2016-04-14

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