EP3097075A4 - Process for preparation of dimethyl-(e)-butenedioate - Google Patents

Process for preparation of dimethyl-(e)-butenedioate Download PDF

Info

Publication number
EP3097075A4
EP3097075A4 EP14812977.8A EP14812977A EP3097075A4 EP 3097075 A4 EP3097075 A4 EP 3097075A4 EP 14812977 A EP14812977 A EP 14812977A EP 3097075 A4 EP3097075 A4 EP 3097075A4
Authority
EP
European Patent Office
Prior art keywords
butenedioate
dimethyl
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP14812977.8A
Other languages
German (de)
English (en)
French (fr)
Other versions
EP3097075A2 (en
Inventor
Rafiuddin DR.
Bhagat Raj PIPAL
Ravindra Reddy UMMADI
Akshay Kant CHATURVEDI
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shilpa Medicare Ltd
Original Assignee
Shilpa Medicare Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shilpa Medicare Ltd filed Critical Shilpa Medicare Ltd
Publication of EP3097075A2 publication Critical patent/EP3097075A2/en
Publication of EP3097075A4 publication Critical patent/EP3097075A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/08—Preparation of carboxylic acid esters by reacting carboxylic acids or symmetrical anhydrides with the hydroxy or O-metal group of organic compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/48—Separation; Purification; Stabilisation; Use of additives
    • C07C67/52—Separation; Purification; Stabilisation; Use of additives by change in the physical state, e.g. crystallisation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
EP14812977.8A 2014-01-24 2014-10-18 Process for preparation of dimethyl-(e)-butenedioate Withdrawn EP3097075A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN308CH2014 IN2014CH00308A (ja) 2014-01-24 2014-10-18
PCT/IB2014/065440 WO2014203231A2 (en) 2014-01-24 2014-10-18 Process for preparation of dimethyl-(e)-butenedioate

Publications (2)

Publication Number Publication Date
EP3097075A2 EP3097075A2 (en) 2016-11-30
EP3097075A4 true EP3097075A4 (en) 2017-06-21

Family

ID=52105418

Family Applications (1)

Application Number Title Priority Date Filing Date
EP14812977.8A Withdrawn EP3097075A4 (en) 2014-01-24 2014-10-18 Process for preparation of dimethyl-(e)-butenedioate

Country Status (3)

Country Link
EP (1) EP3097075A4 (ja)
IN (1) IN2014CH00308A (ja)
WO (1) WO2014203231A2 (ja)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017013672A1 (en) 2015-07-23 2017-01-26 Natco Pharma Ltd Process for the preparation of pharmaceutical grade dimethyl fumarate

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102766050A (zh) * 2012-08-10 2012-11-07 太仓市运通化工厂 一种富马酸二甲酯的合成方法
WO2012170923A1 (en) * 2011-06-08 2012-12-13 Biogen Idec Ma Inc. Process for preparing high purity and crystalline dimethyl fumarate

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3078302A (en) * 1958-09-25 1963-02-19 Monsanto Chemicals Production of dialkyl fumarates
US3905943A (en) * 1973-04-16 1975-09-16 Koppers Co Inc Preparation of fumarates

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012170923A1 (en) * 2011-06-08 2012-12-13 Biogen Idec Ma Inc. Process for preparing high purity and crystalline dimethyl fumarate
CN102766050A (zh) * 2012-08-10 2012-11-07 太仓市运通化工厂 一种富马酸二甲酯的合成方法

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
BERTUS P ET AL: "Asymmetric synthesis of the cyclopentanones related to NCS and N1999A2 antitumor antibiotics", TETRAHEDRON LETTERS, ELSEVIER, AMSTERDAM, NL, vol. 44, no. 16, 14 April 2003 (2003-04-14), pages 3391 - 3395, XP004417075, ISSN: 0040-4039, DOI: 10.1016/S0040-4039(03)00565-3 *
JAMES K BEATTIE ET AL: "Supporting Information The Mechanism of On-Water Catalysis Contents", CHEMISTRY- A EUROPEAN JOURNAL, 1 January 2010 (2010-01-01), pages S1 - S7, XP055369767, Retrieved from the Internet <URL:http://onlinelibrary.wiley.com/store/10.1002/chem.201001705/asset/supinfo/chem_201001705_sm_miscellaneous_information.pdf?v=1&s=165a1caab424e05c9d139c6691608e6d3270002c> [retrieved on 20170505] *
JAMES K. BEATTIE ET AL: "The Mechanism of On-Water Catalysis", CHEMISTRY - A EUROPEAN JOURNAL, vol. 16, no. 30, 6 July 2010 (2010-07-06), pages 8972 - 8974, XP055369770, ISSN: 0947-6539, DOI: 10.1002/chem.201001705 *

Also Published As

Publication number Publication date
IN2014CH00308A (ja) 2015-07-31
EP3097075A2 (en) 2016-11-30
WO2014203231A2 (en) 2014-12-24
WO2014203231A3 (en) 2015-07-30

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