IN2014CH00308A - - Google Patents

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Publication number
IN2014CH00308A
IN2014CH00308A IN308CH2014A IN2014CH00308A IN 2014CH00308 A IN2014CH00308 A IN 2014CH00308A IN 308CH2014 A IN308CH2014 A IN 308CH2014A IN 2014CH00308 A IN2014CH00308 A IN 2014CH00308A
Authority
IN
India
Prior art keywords
butenedioate
preparation
dimethyi
methanol
dimethyl
Prior art date
Application number
Inventor
Pipal Bhagatraj
Rafiuddin
Chaturvedi Akshaykant
Ummadi Raveendrareddy
Original Assignee
Shilpa Medicare Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shilpa Medicare Ltd filed Critical Shilpa Medicare Ltd
Priority to PCT/IB2014/065440 priority Critical patent/WO2014203231A2/en
Priority to EP14812977.8A priority patent/EP3097075A4/en
Priority to IN308CH2014 priority patent/IN2014CH00308A/en
Publication of IN2014CH00308A publication Critical patent/IN2014CH00308A/en

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00Preparation of carboxylic acid esters
    • C07C67/08Preparation of carboxylic acid esters by reacting carboxylic acids or symmetrical anhydrides with the hydroxy or O-metal group of organic compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00Preparation of carboxylic acid esters
    • C07C67/48Separation; Purification; Stabilisation; Use of additives
    • C07C67/52Separation; Purification; Stabilisation; Use of additives by change in the physical state, e.g. crystallisation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13Crystalline forms, e.g. polymorphs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

The present invention relates to a process for preparation of dimethyl-(E)-butenedioate (I). O (I) The process for preparation of dimethyI-(E)-butenedioate (I), comprises reaction of Fumaric acid with methanol in the presence of C2-C4 alkanoyl halide as coupling catalyst.
IN308CH2014 2014-01-24 2014-10-18 IN2014CH00308A (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
PCT/IB2014/065440 WO2014203231A2 (en) 2014-01-24 2014-10-18 Process for preparation of dimethyl-(e)-butenedioate
EP14812977.8A EP3097075A4 (en) 2014-01-24 2014-10-18 Process for preparation of dimethyl-(e)-butenedioate
IN308CH2014 IN2014CH00308A (en) 2014-01-24 2014-10-18

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IN308CH2014 IN2014CH00308A (en) 2014-01-24 2014-10-18

Publications (1)

Publication Number Publication Date
IN2014CH00308A true IN2014CH00308A (en) 2015-07-31

Family

ID=52105418

Family Applications (1)

Application Number Title Priority Date Filing Date
IN308CH2014 IN2014CH00308A (en) 2014-01-24 2014-10-18

Country Status (3)

Country Link
EP (1) EP3097075A4 (en)
IN (1) IN2014CH00308A (en)
WO (1) WO2014203231A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017013672A1 (en) 2015-07-23 2017-01-26 Natco Pharma Ltd Process for the preparation of pharmaceutical grade dimethyl fumarate

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3078302A (en) * 1958-09-25 1963-02-19 Monsanto Chemicals Production of dialkyl fumarates
US3905943A (en) * 1973-04-16 1975-09-16 Koppers Co Inc Preparation of fumarates
PL2718257T3 (en) * 2011-06-08 2018-04-30 Biogen Ma Inc. Process for preparing high purity and crystalline dimethyl fumarate
CN102766050A (en) * 2012-08-10 2012-11-07 太仓市运通化工厂 Method for synthesizing dimethyl fumarate

Also Published As

Publication number Publication date
WO2014203231A2 (en) 2014-12-24
EP3097075A2 (en) 2016-11-30
EP3097075A4 (en) 2017-06-21
WO2014203231A3 (en) 2015-07-30

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