EP3082775A4 - Pilule extrudée à libération prolongée, utilisée pour lutter contre la consommation de substances à mauvais escient - Google Patents

Pilule extrudée à libération prolongée, utilisée pour lutter contre la consommation de substances à mauvais escient Download PDF

Info

Publication number
EP3082775A4
EP3082775A4 EP14871095.7A EP14871095A EP3082775A4 EP 3082775 A4 EP3082775 A4 EP 3082775A4 EP 14871095 A EP14871095 A EP 14871095A EP 3082775 A4 EP3082775 A4 EP 3082775A4
Authority
EP
European Patent Office
Prior art keywords
extended release
abuse deterrent
release abuse
deterrent pill
extruded
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP14871095.7A
Other languages
German (de)
English (en)
Other versions
EP3082775A1 (fr
Inventor
Edwin R. Thompson
Eric R. Thompson
Nicholas R. MYSLINSKI
Steven F. Kemeny
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmaceutical Manufacturing Research Services Inc
Original Assignee
Pharmaceutical Manufacturing Research Services Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US14/457,714 external-priority patent/US10195153B2/en
Application filed by Pharmaceutical Manufacturing Research Services Inc filed Critical Pharmaceutical Manufacturing Research Services Inc
Publication of EP3082775A1 publication Critical patent/EP3082775A1/fr
Publication of EP3082775A4 publication Critical patent/EP3082775A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/36—Opioid-abuse

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Neurology (AREA)
  • Addiction (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Emergency Medicine (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
EP14871095.7A 2013-12-17 2014-12-17 Pilule extrudée à libération prolongée, utilisée pour lutter contre la consommation de substances à mauvais escient Withdrawn EP3082775A4 (fr)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US201361917074P 2013-12-17 2013-12-17
US201361917120P 2013-12-17 2013-12-17
US201461980254P 2014-04-16 2014-04-16
US201461980259P 2014-04-16 2014-04-16
US14/457,714 US10195153B2 (en) 2013-08-12 2014-08-12 Extruded immediate release abuse deterrent pill
PCT/US2014/070942 WO2015095387A1 (fr) 2013-12-17 2014-12-17 Pilule extrudée à libération prolongée, utilisée pour lutter contre la consommation de substances à mauvais escient

Publications (2)

Publication Number Publication Date
EP3082775A1 EP3082775A1 (fr) 2016-10-26
EP3082775A4 true EP3082775A4 (fr) 2017-05-17

Family

ID=53403652

Family Applications (1)

Application Number Title Priority Date Filing Date
EP14871095.7A Withdrawn EP3082775A4 (fr) 2013-12-17 2014-12-17 Pilule extrudée à libération prolongée, utilisée pour lutter contre la consommation de substances à mauvais escient

Country Status (5)

Country Link
EP (1) EP3082775A4 (fr)
JP (2) JP6403780B2 (fr)
AU (3) AU2014364800A1 (fr)
CA (1) CA2934078C (fr)
WO (1) WO2015095387A1 (fr)

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997049384A1 (fr) * 1996-06-26 1997-12-31 Board Of Regents, The University Of Texas System Formulation pharmaceutique extrudable par thermofusion
WO2010140007A2 (fr) * 2009-06-05 2010-12-09 Euro-Celtique S.A. Forme pharmaceutique
US20130028970A1 (en) * 2011-07-29 2013-01-31 Grunenthal Gmbh Tamper-resistant tablet providing immediate drug release
US20140010873A1 (en) * 2012-07-06 2014-01-09 Egalet Ltd. Abuse deterrent pharmaceutical compositions for controlled release
WO2015023675A2 (fr) * 2013-08-12 2015-02-19 Pharmaceutical Manufacturing Research Services, Inc. Comprimé extrudé anti-abus à libération immédiate

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL1765303T5 (pl) * 2004-07-01 2023-05-22 Grünenthal GmbH Tabletka doustna zabezpieczona przed nadużywaniem
US20080152595A1 (en) * 2004-11-24 2008-06-26 Acura Pharmaceuticals, Inc. Methods and compositions for deterring abuse of orally administered pharmaceutical products
DE102007011485A1 (de) * 2007-03-07 2008-09-11 Grünenthal GmbH Darreichungsform mit erschwertem Missbrauch
WO2013158810A1 (fr) * 2012-04-18 2013-10-24 Mallinckrodt Llc Compositions pharmaceutiques à libération immédiate présentant des propriétés de dissuasion d'abus

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997049384A1 (fr) * 1996-06-26 1997-12-31 Board Of Regents, The University Of Texas System Formulation pharmaceutique extrudable par thermofusion
WO2010140007A2 (fr) * 2009-06-05 2010-12-09 Euro-Celtique S.A. Forme pharmaceutique
US20130028970A1 (en) * 2011-07-29 2013-01-31 Grunenthal Gmbh Tamper-resistant tablet providing immediate drug release
US20140010873A1 (en) * 2012-07-06 2014-01-09 Egalet Ltd. Abuse deterrent pharmaceutical compositions for controlled release
WO2015023675A2 (fr) * 2013-08-12 2015-02-19 Pharmaceutical Manufacturing Research Services, Inc. Comprimé extrudé anti-abus à libération immédiate

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO2015095387A1 *

Also Published As

Publication number Publication date
CA2934078C (fr) 2019-08-06
WO2015095387A1 (fr) 2015-06-25
EP3082775A1 (fr) 2016-10-26
AU2019216710A1 (en) 2019-09-12
AU2014364800A1 (en) 2016-07-07
AU2018253567B2 (en) 2019-05-23
CA2934078A1 (fr) 2015-06-25
JP6403780B2 (ja) 2018-10-10
JP6678212B2 (ja) 2020-04-08
JP2019001816A (ja) 2019-01-10
JP2017503780A (ja) 2017-02-02
AU2018253567A1 (en) 2018-11-08

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