EP3013574A1 - System zur herstellung von folienprodukten mit blattprodukte mit unterschiedlichen designs auf aufeinanderfolgenden blätter - Google Patents

System zur herstellung von folienprodukten mit blattprodukte mit unterschiedlichen designs auf aufeinanderfolgenden blätter

Info

Publication number
EP3013574A1
EP3013574A1 EP14742063.2A EP14742063A EP3013574A1 EP 3013574 A1 EP3013574 A1 EP 3013574A1 EP 14742063 A EP14742063 A EP 14742063A EP 3013574 A1 EP3013574 A1 EP 3013574A1
Authority
EP
European Patent Office
Prior art keywords
design
pattern
design pattern
along
equal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP14742063.2A
Other languages
English (en)
French (fr)
Inventor
Mildred Frances GANN-FETTER
Pamela Marie Snyder
Mario Castillo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Procter and Gamble Co
Original Assignee
Procter and Gamble Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Procter and Gamble Co filed Critical Procter and Gamble Co
Publication of EP3013574A1 publication Critical patent/EP3013574A1/de
Withdrawn legal-status Critical Current

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B31MAKING ARTICLES OF PAPER, CARDBOARD OR MATERIAL WORKED IN A MANNER ANALOGOUS TO PAPER; WORKING PAPER, CARDBOARD OR MATERIAL WORKED IN A MANNER ANALOGOUS TO PAPER
    • B31FMECHANICAL WORKING OR DEFORMATION OF PAPER, CARDBOARD OR MATERIAL WORKED IN A MANNER ANALOGOUS TO PAPER
    • B31F1/00Mechanical deformation without removing material, e.g. in combination with laminating
    • B31F1/07Embossing, i.e. producing impressions formed by locally deep-drawing, e.g. using rolls provided with complementary profiles
    • DTEXTILES; PAPER
    • D21PAPER-MAKING; PRODUCTION OF CELLULOSE
    • D21FPAPER-MAKING MACHINES; METHODS OF PRODUCING PAPER THEREON
    • D21F3/00Press section of machines for making continuous webs of paper
    • D21F3/02Wet presses
    • D21F3/08Pressure rolls
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B31MAKING ARTICLES OF PAPER, CARDBOARD OR MATERIAL WORKED IN A MANNER ANALOGOUS TO PAPER; WORKING PAPER, CARDBOARD OR MATERIAL WORKED IN A MANNER ANALOGOUS TO PAPER
    • B31FMECHANICAL WORKING OR DEFORMATION OF PAPER, CARDBOARD OR MATERIAL WORKED IN A MANNER ANALOGOUS TO PAPER
    • B31F2201/00Mechanical deformation of paper or cardboard without removing material
    • B31F2201/07Embossing
    • B31F2201/0707Embossing by tools working continuously
    • B31F2201/0715The tools being rollers
    • B31F2201/0723Characteristics of the rollers
    • B31F2201/0733Pattern

Definitions

  • the sheets may be provided on a continuous roll of a length of web material from which, for example, consecutive individual sheets may be separated by tearing along perforations across the width, and pulled away.
  • the sheets may be provided in a continuous length that is folded in accordion-fashion, and thereby gathered into a consolidated structure resembling a stack, with individual sheets made separable via perforations across the width.
  • the sheets may be provided in stacks of individually pre-cut, stacked sheets from which individual sheets may be drawn consecutively from the top or bottom of the stack.
  • Individual sheets in a stack may be folded and stacked simply, or folded and interleaved to form a stack.
  • interleaving and friction between consecutive sheets may be employed to cause leading sheets, as they are drawn from the stack, to partially draw with them consecutive following sheets, such that, for example, the following sheets are partially drawn through a dispensing opening in the dispenser or container in which the stack is provided and/or stored, for easy access when next needed.
  • Such sheet products may be formed of web materials, typically nonwoven web materials, such as webs formed of natural or synthetic fibers, such as cellulose pulp, polymeric fibers or combinations thereof.
  • Embossing or molding may be performed in a manner or by a technique that not only imparts the visual aspects of the chosen design, but also enhances characteristics such as sheet loft, absorbency, and/or texture that enhances wiping/cleaning efficacy. Embossing or molding may be done by a variety of techniques including rolling and hydroembossing.
  • Fig. 1 is a schematic side view of a roller embossing system and a web material.
  • Fig. 2 is a schematic side view of a hydroembossing system and a web material.
  • Figs. 3A and 3B are schematic plan views of web material bearing features of a design pattern that repeats within a repeat length RL, with the variation of the design with respect to portions of the web of varying lengths SL between separation lines schematically represented by a sine curve.
  • Figs. 4A-4D are schematic plan views of web material bearing features of a design pattern that repeats within a repeat length RL, with the variation of the design with respect to portions of the web of varying lengths SL between separation lines schematically represented by a sine curve.
  • Fig. 5 is a schematic top/plan view of an arrangement such as depicted in Fig. 2, including a view of web material bearing features of a design pattern that repeats along the machine and cross directions within repeat length RL and repeat width RW, with the variation of the design with respect to portions of the web of lengths SL and widths SW between separation lines schematically represented by a sine curve.
  • Figs. 6A and 6B depict plan views of examples of design patterns wherein the pattern repeat lengths are greater than the sheet lengths, and reflecting examples of attributes that minimize the appearance of natural locations for separation lines.
  • Fig. 7 depicts a plan view of an example of a design pattern reflecting examples of attributes that minimize the appearance of natural locations for separation lines.
  • Associated sheets means a plurality of sheets that are consecutively: stacked one on top of another, folded, interleaved and stacked one on top of the other, gathered on a roll, or gathered by accordion folding.
  • At least partially separated applies to and describes two portions of a web material at a location where they are divided by a complete cut; or by a partial cut, perforation or scoring along a separation line, at which the first portion may be separated from the second portion by application of tensile force to the first portion, either without tearing of the web material, or by tearing that propagates along the separation line.
  • continuous means that consecutive, congruous portions of the repeating pattern appear on consecutive sheets.
  • the term "imparting” includes printing the features on the material, impressing the features into the material, embossing the features onto/into the material, or any other technique or process for causing the material to bear visible and/or tactilely-perceptible features of the design.
  • Machine direction with respect to a web material undergoing processing in a manufacturing or processing line that includes imparting the material with a design pattern, means generally parallel to the direction in which the material is conveyed through the line in the process(es) that cause the material to be imparted with a design pattern.
  • cross direction means generally perpendicular to the machine direction.
  • Nonwoven web material means web material formed of fibers that are neither woven nor knitted, including fibers formed of natural or synthetic materials, including but not limited to cellulose fibers, polymer fibers, and combinations thereof.
  • Sheet is a portion of a nonwoven material web of one or both of length or width dimensions smaller than the greater length or width dimensions, respectively, of the nonwoven material web.
  • An "x-y dimension” is a dimension of a sheet or material web measured along a plane approximately defined by the sheet or web when laid and/or extended out flat and lying on a horizontal, planar surface.
  • z-direction with respect to a material web or sheet, is the direction that is orthogonal to the plane approximately defined by the material web or sheet when laid out flat on horizontal, planar surface.
  • manufacturing or processing line relates to the direction of travel of the item being conveyed and/or processed in the line, with the movement of the item through the line being analogous to the movement of water in a stream.
  • a "wipe” is a sheet suitable for use in wiping and/or cleaning any surface.
  • Non-limiting examples include skin cleansing wipes, baby wipes, paper towels, bath tissues, facial tissues, and household cleaning and/or dusting wipes.
  • a first stamp may be used to impart features of a first design to a first sheet; a second stamp may be used to impart features of a second design to a second sheet succeeding the first, a third stamp may be used to impart features of a third design to a third sheet succeeding the second, and so on, and the sheets may then be gathered on a roll, in a stack, etc.
  • a first stamp may be used to impart features of a first design to a first sheet
  • a second stamp may be used to impart features of a second design to a second sheet succeeding the first
  • a third stamp may be used to impart features of a third design to a third sheet succeeding the second, and so on, and the sheets may then be gathered on a roll, in a stack, etc.
  • the design features are imparted by use of a roller or cylinder, e.g. , a printing roller, an embossing roller, a hydroembossing or hydromolding cylinder, etc.
  • a roller or cylinder e.g. , a printing roller, an embossing roller, a hydroembossing or hydromolding cylinder, etc.
  • embossing the roller or cylinder will have an acting surface bearing 3-dimensional features corresponding to the desired design features to be imparted.
  • the roller or cylinder will be paired with an opposing roller or cylinder, the two meeting at a nip.
  • roller embossing roller As the web is passed through the nip, the features of the embossing roller are impressed into the web.
  • a bank or beam of water jets will be positioned adjacent the roller or cylinder, and arranged to direct jets of water toward the cylindrical surface of roller or cylinder.
  • jets of water therefrom impact the web and urge and displace portions thereof to conform to the 3-dimensional features of the roller, thereby imparting the design features to the web material.
  • Roller embossing is described in, for example, PCT Application Pub. No. WO 2008/107845, and references cited therein.
  • Hydroembossing also known as hydromolding
  • hydromolding Hydroembossing
  • a web material 10 may be conveyed into and through the nip between a pair of rollers including an embossing, printing or calender roller 100 and opposing roller 101.
  • the roller 100 may have features of a decorative design reflected in lands 100a and depressions 100b, formed on its outer cylindrical surface by etching, machining or other forming technique. As it passes through the nip between rollers 100 and 101, the web material is imparted with printed, molded or embossed features 11 of the decorative design.
  • Opposing roller 101 may be featureless, or may also have features reflecting a design formed on its rolling surface, which may be complementary or cooperative with the features on roller 100.
  • a web material 10 may be rolled over the surface of a rotating hydroembossing drum or cylinder 102.
  • Cylinder 102 may have formed on its outer surface features reflecting a decorative design, in lands 102a and depressions 102b, in the surface.
  • web material 10 may be passed under one or more banks of hydroembossing jets 103 that expel high-energy streams of water 104 at the web material.
  • the streams 104 impinge the fibers of the material, thereby displacing portions of the fibers into the depressions 102b in the surface of the cylinder 102.
  • the web material is imparted with hydroembossed features 11 of the decorative design.
  • the outer surface of roller 100 or cylinder 102 will have radius r. Accordingly, the circumference of the outer surface of roller 100 or cylinder 102 will be 2 ⁇ . It will be appreciated, then, that features of any decorative design reflected on the roller or cylinder surface will be imparted to the web material such that the design is repeated on the web material along the machine direction, at least, with each complete rotation of the roller or cylinder. On the web material, the repeat length will be, at most, approximately 2 ⁇ , and the repeat frequency will be, at least, approximately 1/2 ⁇ along the machine direction. Of course, the design may be created and features arranged on the roller or cylinder such that it repeats more than once about the circumference as well, and thus, has a repeat length RL shorter than 2 ⁇ and a frequency greater than 1/2 ⁇ along the machine direction.
  • a continuous belt adapted to impart features of a decorative design, and adapted to ride on pulleys, may be used for embossing, molding, printing, hydroembossing, etc.
  • the design pattern repeat length will be less than or equal to the running length of the belt (i.e., the length of the belt if it were cut along a line perpendicular to the machine direction, and laid out flat).
  • the changing appearance of a design pattern imparted to a web along an x-axis parallel with the machine direction may be schematically represented by the changing position of a sine curve 200, where the y-axis would be perpendicular with the machine direction.
  • each y value along the curve 200 corresponds with a particular arrangement of the pattern at a corresponding distance along the x-axis from a starting point.
  • pattern repeat length RL is necessarily less than or equal to approximately 2 ⁇ .
  • the cycle of the sine curve 200 represents a cycle of the repeating design pattern, i.e., the wavelength of the sine curve represents pattern repeat length RL.
  • the web material may be cut or perforated along separation lines 201 spaced apart by a distance representing the intended length SL of individual sheets 300, and the features of the design pattern through its cycle are continuous across a plurality of the sheets 300.
  • SL is selected to be equal to or greater than pattern repeat length RL
  • features of the design will be substantially replicated on two consecutive sheets 300. This is illustrated by way of example in Fig. 3 A, where it can be seen that SL is greater than RL, and each of the depicted consecutive sheets 300 includes more than an entire cycle of the sine curve 200.
  • SL is selected to be less than pattern repeat length RL
  • the design features will not be substantially replicated on two consecutive sheets 300. This is illustrated by way of example in Fig. 3B, where it can be seen that SL is less than RL, and each of any pair of two consecutive sheets 300 bears a differing, less-than-entire-cycle portion of sine curve 200.
  • RL and SL In order to determine the number of sheets of length SL that will be present in a series of consecutive sheets before the pattern on a sheet is replicated by some succeeding sheet, relative the sheet separation lines 201, we first determine RL and SL. Next, we identify the lowest common factor (LCF) which, when multiplied by each of RL and SL, will yield the smallest possible integer in both multiplications.
  • the LCF is the number by which RL and SL may both be multiplied such that the ratio RL/SL may be expressed as a ratio of the smallest possible integers.
  • the integer resulting from the multiplication RL x LCF is the number of sheets N of length SL in a series that will be present in consecutive succession before the begins anew on the next successive sheet, relative the sheet separation lines 201.
  • the number of sheets N of length SL that will be present in succession in a series before the pattern is replicated on the next sheet following the series, relative sheet separation lines 201, is the product of RL and LCF, i.e.,
  • N RL x LCF.
  • series number N is the numerator in the ratio of smallest possible integers, 200/43, equal to 100/21.5.
  • the ratio of RL/SL is 2/1.
  • series number N 2.
  • the ratio of RL/SL is 3/2.
  • series number N 3.
  • the pattern as positioned on the sheets, relative the sheet separation lines 201 is replicated after a series of 3 sheets.
  • series number N be no less than a minimum, e.g., no less than 2, more preferably no less than 3, still more preferably no less than 4, and even more preferably no less than 5.
  • the ratio RL/SL as a ratio of two integers in which the numerator is 5 or a greater integer.
  • SL be equal to or less than RL/2, or more preferably equal to or less than RL/3, even more preferably equal or less than RL/4, or still more preferably equal to or less than RL/5.
  • This feature may be desired by itself, or may be desired in combination with a minimum number for N, as described in the preceding paragraph.
  • a design pattern as reflected by features of a roller or cylinder 101 or 102, and as those features 11 are imparted to a web material 10, can repeat in both the machine direction MD and the cross direction, and can have a repeat length RL and repeat width RW along those directions, respectively.
  • the arrangement of the design pattern as it changes along each direction again, can be schematically represented by sine curves 200. It can be appreciated that, depending upon the method of manufacture of the product, consecutive sheets 300 in a series may be cut and gathered into a supply according to their order along the machine direction or the cross direction.
  • sheets 300a, 300b, 300c, 300d, etc., appearing in succession along the machine direction may be cut or perforated along cross direction separation lines 201a, and gathered and collected into a supply with consecutive sheets presented according to the same order of succession (or the reverse thereof).
  • the pattern repeat length RL is less than or equal to 2 ⁇ .
  • sheets 300i, 300H, 300iii, 300iv, etc. appearing in succession along the cross direction may be cut or perforated along machine direction separation lines 201b, and may be gathered and collected into a supply with
  • pattern repeat length RL sheet length SL and series number N
  • RW pattern repeat width
  • sheet width SW sheet width SW
  • series number N along the cross direction
  • a roller 101 or cylinder 102 will have a fixed axial acting length along which it bears features adapted to impart features of the selected design pattern to the web material. Therefore, the pattern repeat width RW is, at most, less than or equal to that axial acting length.
  • Fig. 5 reflects a design pattern that has design elements that are discontinuous in both the machine direction and cross direction. It is formed by series of discrete, individually identifiable design elements separated by linear pathways of substantially unadorned space between them. These pathways are arranged in the machine and cross directions. Separation lines 201a, 201b may be arranged along these pathways. It may be appreciated that a web bearing such a pattern may, most preferably, be cut into sheets along separation lines located in these unadorned pathways as suggested in Fig. 5, to cause discrete design elements to be approximately centered and appear balanced and/or symmetrical on the sheets, and/or to avoid dividing the discrete design elements, compromising their aesthetic appeal and/or creating a haphazard appearance in the separated sheet products. In order to maintain the centered, symmetrical and/or balanced locations of the discrete design elements relative the separation lines, it may be necessary to implement a system and method for maintaining alignment of the pattern relative the separation lines.
  • a registration system may add complexity and cost to the manufacturing line.
  • a design pattern in combination with a repeat length in the machine or cross direction greater than sheet length or width which may further include any of the mathematical relationships described above, is that the pattern may be composed and arranged such that there are no apparently natural pathways for the locations of separation lines. Examples of such patterns on portions of web are depicted in Figs. 6A and 6B, shown with possible (but not necessarily preferred) locations of separation lines 201
  • a pattern may be configured to change in content and arrangement of particular design elements thereof, along one or both of machine direction MD and cross direction CD, and along its repeat length, such that consecutive individual sheets defined by separation lines 201 will have varying appearances, regardless of the particular locations of the separation lines.
  • the pattern may be configured such that there is no apparent natural line of demarcation between design elements (or groups or combinations of them) for a location of a separation line. Granting that individual perceptions may be subjective, the general result is that individual sheets are less likely to be perceived as having a haphazard appearance because of a perceived off-center, asymmetrical or unbalanced location of a design element relative the separation lines, regardless of where separation lines fall relative the pattern.
  • design element means any discrete visible feature comprising a deposit of ink, or any impression of a feature or image or portion thereof, that is imprinted on or embossed into the web.
  • embossing or bonding roller Where a design pattern is imparted to a web by use of an embossing or bonding roller, it may be desirable particularly that no such unadorned pathway exists along the cross direction.
  • the absence of such a corresponding pathway of depression between lands on the surface of an embossing roller may help reduce or eliminate periodic, abrupt changes in the forces imposed on the roller surface and transferred through the roller to its axle and/or bearing mechanism, thereby reducing equipment wear and/or the need for shock-absorbing equipment.
  • embossment is done via embossing or bonding roller, where it is desired for aesthetic design or other purposes that the pattern include such machine- or cross-direction unadorned pathways
  • another attribute that may be imparted to the pattern is to limit the width of such unadorned pathways so that they are not immediately noticeable and/or do not form apparent natural pathways for the location of separation lines.
  • the depicted design has an unadorned cross-direction pathway between the depicted
  • the pathway has a width APW, in which no portion of a design element is present. It is believed that limiting the width of such a pathway to 7 percent or less, more preferably 5 percent or less, of the dimension of the sheet measured between the separation lines that are parallel to the pathway (in the example depicted in Fig. 7, the ratio APW/SL, expressed as a percentage) is effective for avoiding the appearance of a natural pathway for the location of a separation line, i.e., a division between sequential sheets. Where the design is imparted to the web by use of an embossing roller, limiting the width of a cross-direction unadorned pathway may also serve to minimize equipment wear from periodic abrupt changes in embossing pressure, as described above.
  • lines AL form angles with the machine direction between 10 degrees and 80 degrees, more preferably between 20 degrees and 70 degrees, even more preferably between 30 degrees and 60 degrees, and most preferably between 40 degrees and 50 degrees, for example, 45 degrees.
  • a design pattern includes any realistic or fanciful image of all or a portion of a person, animal, anthropomorphic character or cartoon character, which image includes at least the head and/or face
  • another attribute that may be imparted to the pattern to avoid giving individual sheets a haphazard appearance is to limit the size of the image. It is believed that such an image is effectively limited in size when a rectangle drawn with its sides parallel to the machine and cross directions, and circumscribing the image in its congruous entirety, occupies no more than 10 percent of the area of the sheet as established by the separation lines.
  • the pattern depicted in Fig. 6 A includes fanciful images of a bird, a giraffe and an elephant, each of which includes a head and/or face.
  • the design pattern may be configured such that separation lines may be spaced and located partially or completely independently of the dimensions of the pattern, reducing or eliminate the need for use of a registration system or other system for maintaining alignment of the pattern relative the separation lines.
  • a system for manufacturing pluralities of consecutive sheets bearing successively varying arrangements of design features comprising: a pattern imparting roller having a radius r, a rotation axis, an outer circumference 2nr, and a substantially cylindrical acting surface reflecting features of a design pattern thereon, a machine direction tangent to the acting surface and perpendicular to the rotation axis, and a cross direction parallel to the rotation axis, the acting surface having an axial acting surface length AL measured along the cross direction, the design pattern having a machine direction repeat length RLM; and a separating mechanism disposed downstream of the pattern imparting roller, configured to effect repeated and spaced complete cutting, or repeated and spaced partial cutting, perforating or scoring along separation lines, between portions of a material web, the separation lines being spaced apart on the web by sheet length SL measured along the machine direction, wherein SL is less than RLM; and wherein the design pattern has one or more of the following attributes: the design pattern has no linear, continuous unadorned pathway along the cross direction that has a pathway width greater than 7
  • a system for manufacturing pluralities of consecutive sheets bearing successively varying arrangements of design features comprising: a pattern imparting roller having a radius r, a rotation axis, an outer circumference 2nr, a substantially cylindrical acting surface reflecting features of a design pattern thereon, a machine direction tangent to the acting surface and perpendicular to the rotation axis, and a cross direction parallel to the rotation axis, the acting surface having an axial acting surface length AL measured along the cross direction, the design pattern having a cross direction repeat length RLC; and a separating mechanism disposed downstream of the pattern imparting roller, configured to effect spaced complete cutting, or spaced partial cutting, perforating or scoring, along separation lines, between portions of a material web, the separation lines being spaced apart on the web by sheet length SL measured along the cross direction, wherein SL is less than RLC; and wherein the design pattern has one or more of the following attributes: the design pattern has no linear, continuous unadorned pathway along the machine direction that has a pathway width greater than 7 percent of SL

Landscapes

  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Shaping Of Tube Ends By Bending Or Straightening (AREA)
EP14742063.2A 2013-06-27 2014-06-26 System zur herstellung von folienprodukten mit blattprodukte mit unterschiedlichen designs auf aufeinanderfolgenden blätter Withdrawn EP3013574A1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US13/928,533 US20150000854A1 (en) 2013-06-27 2013-06-27 Sheet products bearing designs that vary among successive sheets, and apparatus and methods for producing the same
PCT/US2014/044208 WO2014210233A1 (en) 2013-06-27 2014-06-26 System for producing sheet products bearing designs that vary among successive sheets

Publications (1)

Publication Number Publication Date
EP3013574A1 true EP3013574A1 (de) 2016-05-04

Family

ID=51213000

Family Applications (1)

Application Number Title Priority Date Filing Date
EP14742063.2A Withdrawn EP3013574A1 (de) 2013-06-27 2014-06-26 System zur herstellung von folienprodukten mit blattprodukte mit unterschiedlichen designs auf aufeinanderfolgenden blätter

Country Status (3)

Country Link
US (1) US20150000854A1 (de)
EP (1) EP3013574A1 (de)
WO (1) WO2014210233A1 (de)

Families Citing this family (88)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105849275B (zh) 2013-06-25 2020-03-17 普罗格诺西斯生物科学公司 检测样品中生物靶标的空间分布的方法和系统
EP3530752B1 (de) 2015-04-10 2021-03-24 Spatial Transcriptomics AB Räumlich getrennte multiplex-nukleinsäureanalyse von biologischen proben
US11519033B2 (en) 2018-08-28 2022-12-06 10X Genomics, Inc. Method for transposase-mediated spatial tagging and analyzing genomic DNA in a biological sample
EP3844306A2 (de) 2018-08-28 2021-07-07 10X Genomics, Inc. Erhöhung der räumlichen array-auflösung
WO2020047005A1 (en) 2018-08-28 2020-03-05 10X Genomics, Inc. Resolving spatial arrays
EP3894585A2 (de) 2018-12-10 2021-10-20 10X Genomics, Inc. Erzeugung von erfassungssonden zur räumlichen analyse
US11649485B2 (en) 2019-01-06 2023-05-16 10X Genomics, Inc. Generating capture probes for spatial analysis
US11926867B2 (en) 2019-01-06 2024-03-12 10X Genomics, Inc. Generating capture probes for spatial analysis
WO2020176788A1 (en) 2019-02-28 2020-09-03 10X Genomics, Inc. Profiling of biological analytes with spatially barcoded oligonucleotide arrays
EP3938538A1 (de) 2019-03-15 2022-01-19 10X Genomics, Inc. Verfahren zur verwendung von räumlichen anordnungen für einzelzellsequenzierung
WO2020198071A1 (en) 2019-03-22 2020-10-01 10X Genomics, Inc. Three-dimensional spatial analysis
EP3976820A1 (de) 2019-05-30 2022-04-06 10X Genomics, Inc. Verfahren zum nachweis der räumlichen heterogenität einer biologischen probe
CN114761992B (zh) 2019-10-01 2023-08-08 10X基因组学有限公司 用于识别组织样品中的形态学模式的系统和方法
US20210130881A1 (en) 2019-11-06 2021-05-06 10X Genomics, Inc. Imaging system hardware
WO2021091611A1 (en) 2019-11-08 2021-05-14 10X Genomics, Inc. Spatially-tagged analyte capture agents for analyte multiplexing
EP4025711A2 (de) 2019-11-08 2022-07-13 10X Genomics, Inc. Erhöhung der spezifität einer analytbindung
WO2021097255A1 (en) 2019-11-13 2021-05-20 10X Genomics, Inc. Generating capture probes for spatial analysis
CN115004260A (zh) 2019-11-18 2022-09-02 10X基因组学有限公司 用于组织分类的系统和方法
AU2020388573A1 (en) 2019-11-21 2022-06-23 10X Genomics, Inc, Spatial analysis of analytes
CN117746422A (zh) 2019-11-22 2024-03-22 10X基因组学有限公司 使用基准对齐对分析物进行空间分析的系统和方法
SG11202106899SA (en) 2019-12-23 2021-09-29 10X Genomics Inc Methods for spatial analysis using rna-templated ligation
CN115715329A (zh) 2020-01-10 2023-02-24 10X基因组学有限公司 确定生物样品中靶核酸位置的方法
US11702693B2 (en) 2020-01-21 2023-07-18 10X Genomics, Inc. Methods for printing cells and generating arrays of barcoded cells
US11732299B2 (en) 2020-01-21 2023-08-22 10X Genomics, Inc. Spatial assays with perturbed cells
US11821035B1 (en) 2020-01-29 2023-11-21 10X Genomics, Inc. Compositions and methods of making gene expression libraries
US11898205B2 (en) 2020-02-03 2024-02-13 10X Genomics, Inc. Increasing capture efficiency of spatial assays
US11732300B2 (en) 2020-02-05 2023-08-22 10X Genomics, Inc. Increasing efficiency of spatial analysis in a biological sample
US20230047782A1 (en) 2020-02-07 2023-02-16 10X Genomics, Inc. Quantitative and automated permeabilization performance evaluation for spatial transcriptomics
US11835462B2 (en) 2020-02-11 2023-12-05 10X Genomics, Inc. Methods and compositions for partitioning a biological sample
WO2021168278A1 (en) 2020-02-20 2021-08-26 10X Genomics, Inc. METHODS TO COMBINE FIRST AND SECOND STRAND cDNA SYNTHESIS FOR SPATIAL ANALYSIS
EP4107282A1 (de) 2020-02-21 2022-12-28 10X Genomics, Inc. Erfassung genetischer ziele mit einem hybridisierungsansatz
US11891654B2 (en) 2020-02-24 2024-02-06 10X Genomics, Inc. Methods of making gene expression libraries
US11768175B1 (en) 2020-03-04 2023-09-26 10X Genomics, Inc. Electrophoretic methods for spatial analysis
EP4242325A3 (de) 2020-04-22 2023-10-04 10X Genomics, Inc. Verfahren zur räumlichen analyse unter verwendung von gezieltem rna-abbau
US20230265491A1 (en) 2020-05-04 2023-08-24 10X Genomics, Inc. Spatial transcriptomic transfer modes
EP4153776A1 (de) 2020-05-22 2023-03-29 10X Genomics, Inc. Räumliche analyse zur erkennung von sequenzvarianten
WO2021237056A1 (en) 2020-05-22 2021-11-25 10X Genomics, Inc. Rna integrity analysis in a biological sample
EP4153775A1 (de) 2020-05-22 2023-03-29 10X Genomics, Inc. Simultane räumlich-zeitliche messung der genexpression und der zellaktivität
WO2021242834A1 (en) 2020-05-26 2021-12-02 10X Genomics, Inc. Method for resetting an array
EP4025692A2 (de) 2020-06-02 2022-07-13 10X Genomics, Inc. Nukleinsäure-bibliotheksverfahren
CN116249785A (zh) 2020-06-02 2023-06-09 10X基因组学有限公司 用于抗原-受体的空间转录组学
WO2021252499A1 (en) 2020-06-08 2021-12-16 10X Genomics, Inc. Methods of determining a surgical margin and methods of use thereof
EP4165207A1 (de) 2020-06-10 2023-04-19 10X Genomics, Inc. Verfahren zur bestimmung einer position eines analyten in einer biologischen probe
US20230279474A1 (en) 2020-06-10 2023-09-07 10X Genomics, Inc. Methods for spatial analysis using blocker oligonucleotides
AU2021294334A1 (en) 2020-06-25 2023-02-02 10X Genomics, Inc. Spatial analysis of DNA methylation
US11761038B1 (en) 2020-07-06 2023-09-19 10X Genomics, Inc. Methods for identifying a location of an RNA in a biological sample
US11981960B1 (en) 2020-07-06 2024-05-14 10X Genomics, Inc. Spatial analysis utilizing degradable hydrogels
US20230287475A1 (en) 2020-07-31 2023-09-14 10X Genomics, Inc. De-crosslinking compounds and methods of use for spatial analysis
US11981958B1 (en) 2020-08-20 2024-05-14 10X Genomics, Inc. Methods for spatial analysis using DNA capture
EP4200441A1 (de) 2020-09-15 2023-06-28 10X Genomics, Inc. Verfahren zur freisetzung einer erweiterten erfassungssonde aus einem substrat und verwendungen davon
AU2021345133A1 (en) 2020-09-16 2023-03-30 10X Genomics, Inc. Methods of determining the location of an analyte in a biological sample using a plurality of wells
US20230351619A1 (en) 2020-09-18 2023-11-02 10X Genomics, Inc. Sample handling apparatus and image registration methods
EP4213993A2 (de) 2020-09-18 2023-07-26 10X Genomics, Inc. Probenhandhabungsvorrichtung und flüssigkeitsausgabeverfahren
US11926822B1 (en) 2020-09-23 2024-03-12 10X Genomics, Inc. Three-dimensional spatial analysis
WO2022081643A2 (en) 2020-10-13 2022-04-21 10X Genomics, Inc. Compositions and methods for generating recombinant antigen binding molecules from single cells
US20240018572A1 (en) 2020-10-22 2024-01-18 10X Genomics, Inc. Methods for spatial analysis using rolling circle amplification
EP4222283A1 (de) 2020-11-06 2023-08-09 10X Genomics, Inc. Zusammensetzungen und verfahren zur bindung eines analyten an eine erfassungssonde
AU2021385065A1 (en) 2020-11-18 2023-06-15 10X Genomics, Inc. Methods and compositions for analyzing immune infiltration in cancer stroma to predict clinical outcome
US11827935B1 (en) 2020-11-19 2023-11-28 10X Genomics, Inc. Methods for spatial analysis using rolling circle amplification and detection probes
AU2021409136A1 (en) 2020-12-21 2023-06-29 10X Genomics, Inc. Methods, compositions, and systems for capturing probes and/or barcodes
WO2022147005A1 (en) 2020-12-30 2022-07-07 10X Genomics, Inc. Methods for analyte capture determination
WO2022147296A1 (en) 2020-12-30 2022-07-07 10X Genomics, Inc. Cleavage of capture probes for spatial analysis
US20240093290A1 (en) 2021-01-29 2024-03-21 10X Genomics, Inc. Method for transposase mediated spatial tagging and analyzing genomic dna in a biological sample
WO2022198068A1 (en) 2021-03-18 2022-09-22 10X Genomics, Inc. Multiplex capture of gene and protein expression from a biological sample
AU2022256031A1 (en) 2021-04-05 2023-10-12 10X Genomics, Inc. Recombinant ligase composition and uses thereof
WO2022221425A1 (en) 2021-04-14 2022-10-20 10X Genomics, Inc. Methods of measuring mislocalization of an analyte
WO2022226057A1 (en) 2021-04-20 2022-10-27 10X Genomics, Inc. Methods for assessing sample quality prior to spatial analysis using templated ligation
WO2022236054A1 (en) 2021-05-06 2022-11-10 10X Genomics, Inc. Methods for increasing resolution of spatial analysis
EP4347879A1 (de) 2021-06-03 2024-04-10 10X Genomics, Inc. Verfahren, zusammensetzungen, kits und systeme zur verbesserung der analyterfassung zur räumlichen analyse
WO2022271820A1 (en) 2021-06-22 2022-12-29 10X Genomics, Inc. Spatial detection of sars-cov-2 using templated ligation
WO2023287765A1 (en) 2021-07-13 2023-01-19 10X Genomics, Inc. Methods for spatial analysis using targeted probe silencing
WO2023018799A1 (en) 2021-08-12 2023-02-16 10X Genomics, Inc. Methods, compositions and systems for identifying antigen-binding molecules
WO2023034489A1 (en) 2021-09-01 2023-03-09 10X Genomics, Inc. Methods, compositions, and kits for blocking a capture probe on a spatial array
WO2023044071A1 (en) 2021-09-17 2023-03-23 10X Genomics, Inc. Systems and methods for image registration or alignment
WO2023076345A1 (en) 2021-10-26 2023-05-04 10X Genomics, Inc. Methods for spatial analysis using targeted rna capture
AU2022387613A1 (en) 2021-11-10 2024-05-30 10X Genomics, Inc. Methods for identification of antigen-binding molecules
WO2023102313A1 (en) 2021-11-30 2023-06-08 10X Genomics, Inc. Systems and methods for identifying regions of aneuploidy in a tissue
EP4305195A2 (de) 2021-12-01 2024-01-17 10X Genomics, Inc. Verfahren, zusammensetzungen und systeme für verbesserten in-situ-nachweis von analyten und raumanalyse
WO2023122033A1 (en) 2021-12-20 2023-06-29 10X Genomics, Inc. Self-test for pathology/histology slide imaging device
WO2023159028A1 (en) 2022-02-15 2023-08-24 10X Genomics, Inc. Systems and methods for spatial analysis of analytes using fiducial alignment
WO2023172670A2 (en) 2022-03-11 2023-09-14 10X Genomics, Inc. Sample handling apparatus and fluid delivery methods
WO2023229982A2 (en) 2022-05-24 2023-11-30 10X Genomics, Inc. Porous structure confinement for convection suppression
WO2024015578A1 (en) 2022-07-15 2024-01-18 10X Genomics, Inc. Methods for determining a location of a target nucleic acid in a biological sample
WO2024031068A1 (en) 2022-08-05 2024-02-08 10X Genomics, Inc. Systems and methods for immunofluorescence quantification
WO2024036191A1 (en) 2022-08-10 2024-02-15 10X Genomics, Inc. Systems and methods for colocalization
WO2024044703A1 (en) 2022-08-24 2024-02-29 10X Genomics, Inc. Compositions and methods for antigenic epitope mapping in biological samples
WO2024081212A1 (en) 2022-10-10 2024-04-18 10X Genomics, Inc. In vitro transcription of spatially captured nucleic acids
WO2024086167A2 (en) 2022-10-17 2024-04-25 10X Genomics, Inc. Methods, compositions, and kits for determining the location of an analyte in a biological sample

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6348131B1 (en) * 1999-11-12 2002-02-19 Fort James Corporation Multi-ply embossed absorbent paper products
ITFI20050033A1 (it) * 2005-03-01 2006-09-02 Perini Fabio Spa Rullo goffratore, dispositivo goffratore comprendente detto rullo ed articolo di materiale cartaceo realizzato con detto dispositivo goffratore
US7842163B2 (en) * 2005-12-15 2010-11-30 Kimberly-Clark Worldwide, Inc. Embossed tissue products
US7771648B2 (en) 2006-04-06 2010-08-10 The Procter & Gamble Company One-dimensional continuous molded element
US20080216975A1 (en) 2007-03-05 2008-09-11 James Paul Farwig Deeply embossed roll paper products having reduced gapping on the machine direction edges
ITFI20070057A1 (it) * 2007-03-09 2008-09-10 Perini Fabio Spa Materiale in foglio goffrato, gruppo goffratore e metodo per la sua produzione.

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See references of WO2014210233A1 *

Also Published As

Publication number Publication date
WO2014210233A1 (en) 2014-12-31
US20150000854A1 (en) 2015-01-01

Similar Documents

Publication Publication Date Title
US20150000854A1 (en) Sheet products bearing designs that vary among successive sheets, and apparatus and methods for producing the same
KR102540278B1 (ko) 패턴이 있는 티슈 제품
EP1855876B2 (de) Prägerolle, prägevorrichtung mit der rolle
ES2684440T3 (es) Producto fibroso, rodillo de gofrado para producir tal producto fibroso, y dispositivo y método para producir tal producto fibroso
US8389092B2 (en) Stack of folded material
US8920905B2 (en) Fibrous product with a rastered embossing and method for producing same
CN103189292B (zh) 交互折叠的吸收性片产品的堆叠
NO323755B1 (no) Pregert absorberende papir med kombinerte monstre
JP2010535111A (ja) エンボス加工装置
US3326365A (en) Napkins or similar articles and method of manufacturing same
EP2999820A1 (de) Verfahren zur herstellung eines saugfähigen papierprodukts mit visuellen elementen
CN103813970A (zh) 交互折叠的吸收性片材制品的堆叠及其形成方法
CN103997940A (zh) 交错折叠式餐巾和用于交错折叠餐巾的方法
US20150001783A1 (en) Sheet products bearing designs that vary among successive sheets, and apparatus and methods for producing the same
CN107000951A (zh) 一种用于吸收性基片幅的复卷机和卷绕方法
WO2015186052A1 (en) Process and apparatus for embossing tissue plies
MX2011005775A (es) Rodillo de estampado en relieve para producir productos fibrosos con un relieve entramado, dispositivo que emplea dicho rodillo de estampado en relieve y proyecciones de en relieve en dicho rodillo de estampado en relieve.
WO2014190105A1 (en) Absorbent paper product having visual elements
EP3154775B1 (de) Geprägtes mehrlagiges tissueprodukt
CN215882785U (zh) 一种新型卫生卷纸压花复合机构

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20151117

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

AX Request for extension of the european patent

Extension state: BA ME

DAX Request for extension of the european patent (deleted)
STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20160817