EP2967875B1 - Vorrichtungen zum verlängern von knochen - Google Patents

Vorrichtungen zum verlängern von knochen Download PDF

Info

Publication number
EP2967875B1
EP2967875B1 EP14769378.2A EP14769378A EP2967875B1 EP 2967875 B1 EP2967875 B1 EP 2967875B1 EP 14769378 A EP14769378 A EP 14769378A EP 2967875 B1 EP2967875 B1 EP 2967875B1
Authority
EP
European Patent Office
Prior art keywords
implant
bone
enlarged
assembly
extension
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
EP14769378.2A
Other languages
English (en)
French (fr)
Other versions
EP2967875A2 (de
EP2967875A4 (de
Inventor
Thomas D. MCGEE
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Osteoceramics Inc
Original Assignee
Osteoceramics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Osteoceramics Inc filed Critical Osteoceramics Inc
Publication of EP2967875A2 publication Critical patent/EP2967875A2/de
Publication of EP2967875A4 publication Critical patent/EP2967875A4/de
Application granted granted Critical
Publication of EP2967875B1 publication Critical patent/EP2967875B1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/28—Bones
    • A61F2/2814—Bone stump caps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/28—Bones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/28—Bones
    • A61F2002/2817—Bone stimulation by chemical reactions or by osteogenic or biological products for enhancing ossification, e.g. by bone morphogenetic or morphogenic proteins [BMP] or by transforming growth factors [TGF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/28—Bones
    • A61F2002/2825—Femur
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/28—Bones
    • A61F2002/286—Bone stimulation by mechanical vibrations for enhancing ossification
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/30767—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
    • A61F2/30771—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth applied in original prostheses, e.g. holes or grooves
    • A61F2002/30772—Apertures or holes, e.g. of circular cross section
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/30767—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
    • A61F2/30771—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth applied in original prostheses, e.g. holes or grooves
    • A61F2002/3082—Grooves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/50—Prostheses not implantable in the body
    • A61F2/78—Means for protecting prostheses or for attaching them to the body, e.g. bandages, harnesses, straps, or stockings for the limb stump
    • A61F2002/7887—Means for protecting prostheses or for attaching them to the body, e.g. bandages, harnesses, straps, or stockings for the limb stump for connecting limb exoprostheses to the stump bone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0058—Additional features; Implant or prostheses properties not otherwise provided for
    • A61F2250/0065—Additional features; Implant or prostheses properties not otherwise provided for telescopic

Claims (14)

  1. Implantatbaugruppe zum Verbessern einer Knochenverlängerung eines amputierten lebenden Knochens (100), wobei die genannte Baugruppe Folgendes umfasst:
    ein Verlängerungsimplantat (108, 408, 508, 608, 708, 808) mit einem ersten Ende, einem zweiten Ende, einer Außenfläche, einer internen Röhre (425, 525, 825) und einem Durchmesser, wobei das erste Ende zum Einführen in lebenden Knochen ausgelegt ist; und
    ein vergrößertes Implantat (110, 210, 310, 410, 510, 610 710, 810) mit einem ersten Ende, einem zweiten Ende, einer Außenfläche und einer internen Röhre (220, 320, 520, 820), wobei die interne Röhre (425, 525, 825) des Verlängerungsimplantats (108, 408, 508, 608, 708, 808) in Fluidverbindung mit der internen Röhre (220, 320, 520, 820) des vergrößerten Implantats (110, 210, 310, 410, 510, 610 710, 810) ist, wobei das erste Ende des vergrößerten Implantats (110, 210, 310, 410, 510, 610 710, 810) mit dem zweiten Ende des Verlängerungsimplantants (108, 408, 508, 608, 708, 808) kombiniert wird und wobei das vergrößerte Implantat (110, 210, 310, 410, 510, 610 710, 810) einen Durchmesser hat, der größer ist als der Durchmesser des Verlängerungsimplantats (108, 408, 508, 608, 708, 808), dadurch gekennzeichnet, dass die Außenfläche des vergrößerten Implantats ferner externe Nuten (218, 318, 418, 518) in Fluidverbindung mit der internen Röhre (220, 320, 520, 820) des vergrößerten Implantats (110, 210, 310, 410, 510, 610 710, 810) hat, wobei die genannten externen Nuten (218, 318, 418, 518) zum Bieten von Zugang zu Knochenregenerationselementen dienen, die Knochenbildung um das vergrößerte Implantat (110, 210, 310, 410, 510, 610 710, 810) führen.
  2. Implantatbaugruppe nach Anspruch 1, wobei das vergrößerte Implantat (110, 210, 310, 410, 510, 610 710, 810) mit einer Gliedmaßenprothese kombiniert wird.
  3. Implantatbaugruppe nach Anspruch 1, wobei das vergrößerte Implantat (110, 210, 310, 410, 510, 610 710, 810) ferner Öffnungen (212, 214, 312, 412, 414, 512, 514, 812) in Fluidverbindung mit der internen Röhre (220, 320, 520, 820) des vergrößerten Implantats (110, 210, 310, 410, 510, 610 710, 810) umfasst, wobei die genannten Öffnungen (212, 214, 312, 314, 412, 414, 512, 514, 812) zum Bieten von Zugang zu Knochenregenerationselementen dienen, die Knochenbildung um das vergrößerte Implantat (110, 210, 310, 410, 510, 610 710, 810) leiten.
  4. Implantatbaugruppe nach Anspruch 1, wobei die interne Röhre (425, 525, 825) des Verlängerungsimplantats (108, 408, 508, 608, 708, 808) ferner eine Seitenwand umfasst und wobei das Verlängerungsimplantat (108, 408, 508, 608, 708, 808) eine Öffnung (432, 532) in der Seitenwand hat, um den Fluss von Fluid von der internen Röhre (425, 525, 825) des Verlängerungsimplantats (108, 408, 508, 608, 708, 808) zur Außenfläche des Verlängerungsimplantats (108, 408, 508, 608, 708, 808) zuzulassen, um beim Leiten von Knochenbildung um das vergrößerte Implantat (110, 210, 310, 410, 510, 610 710, 810) zu helfen.
  5. Implantatbaugruppe nach Anspruch 1, wobei das Verlängerungsimplantat (108, 408, 508, 608, 708, 808) und das vergrößerte Implantat (110, 210, 310, 410, 510, 610 710, 810) Tricalciumphosphat umfassen.
  6. Implantatbaugruppe nach Anspruch 1, wobei das Verlängerungsimplantat (108, 408, 508, 608, 708, 808) und das vergrößerte Implantat (110, 210, 310, 410, 510, 610 710, 810) aus einem biologisch aktiven lasttragenden Material gefertigt sind.
  7. Implantatbaugruppe nach Anspruch 1, wobei das Verlängerungsimplantat (108, 408, 508, 608, 708, 808) und das vergrößerte Implantat (110, 210, 310, 410, 510, 610 710, 810) kombiniert werden, um dadurch eine einzige Baugruppe herzustellen.
  8. Implantatbaugruppe nach Anspruch 1, die ferner eine Käfigbaugruppe zum Tragen und Bereitstellen von dynamischen Kräften für das Verlängerungsimplantat (108, 408, 508, 608, 708, 808) und das vergrößerte Implantat (110, 210, 310, 410, 510, 610 710, 810) umfasst.
  9. Implantatbaugruppe nach Anspruch 8, wobei die Käfigbaugruppe ferner ein axiales Spannungselement (840) mit einem zum Kombinieren mit dem lebenden Knochen (100) konfigurierten ersten Ende und einem mit dem zweiten Ende des vergrößerten Implantats (110, 210, 310, 410, 510, 610, 710, 810) kombinierten zweiten Ende umfasst, wobei das genannte axiale Spannungselement (840) zum Passieren durch die internen Röhren (425, 525, 825, 220, 320, 520, 820) des Verlängerungsimplantats (108, 408, 508, 608, 708, 808) und vergrößerten Implantats (110, 210, 310, 410, 510, 610 710, 810) ausgelegt ist.
  10. Implantatbaugruppe nach Anspruch 8, wobei die Käfigbaugruppe ferner ein axiales Band (843) mit einem zum Kombinieren mit dem lebenden Knochen (100) konfigurierten ersten Ende und einem mit dem zweiten Ende des vergrößerten Implantats (110, 210, 310, 410, 510, 610 710, 810) kombinierten zweiten Ende umfasst, wobei das genannte axiale Band (854) so ausgelegt ist, dass es um die Außenfläche des Verlängerungsimplantats (108, 408, 508, 608, 708, 808) und die Außenfläche des vergrößerten Implantats (110, 210, 310, 410, 510, 610 710, 810) herum verläuft.
  11. Baugruppe nach Anspruch 10, die ferner einen Anker (820, 850) zum Kombinieren des axialen Spannungselements (840) mit dem Knochen (100) umfasst.
  12. Baugruppe nach Anspruch 11, wobei der Anker (820, 850) relativ zu dem vergrößerten Implantat (110, 210, 310, 410, 510, 610 710, 810) justiert werden kann, um dadurch eine Verstellung des axialen Spannungselements (840) zuzulassen.
  13. Baugruppe nach Anspruch 8, die ferner eine Endkappe (836) zum Kombinieren des axialen Spannungselements (840) mit dem zweiten Ende des vergrößerten Implantats (110, 210, 310, 410, 510, 610 710, 810) umfasst.
  14. Baugruppe nach Anspruch 9, die ferner ein Stabilisierungsband (830) umfasst, kombiniert mit dem ersten Ende des vergrößerten Implantats (110, 210, 310, 410, 510, 610 710, 810), wobei das genannte Stabilisierungsband (830) auswärts in Richtung des axialen Bandes (854) und in Verbindung damit verläuft.
EP14769378.2A 2013-03-15 2014-03-12 Vorrichtungen zum verlängern von knochen Active EP2967875B1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361787985P 2013-03-15 2013-03-15
PCT/US2014/023895 WO2014150658A2 (en) 2013-03-15 2014-03-12 Devices, systems, and methods for elongating bone

Publications (3)

Publication Number Publication Date
EP2967875A2 EP2967875A2 (de) 2016-01-20
EP2967875A4 EP2967875A4 (de) 2016-11-16
EP2967875B1 true EP2967875B1 (de) 2017-12-20

Family

ID=51569694

Family Applications (1)

Application Number Title Priority Date Filing Date
EP14769378.2A Active EP2967875B1 (de) 2013-03-15 2014-03-12 Vorrichtungen zum verlängern von knochen

Country Status (3)

Country Link
US (3) US9039781B2 (de)
EP (1) EP2967875B1 (de)
WO (1) WO2014150658A2 (de)

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3787900A (en) 1971-06-09 1974-01-29 Univ Iowa State Res Found Artificial bone or tooth prosthesis material
US5019087A (en) 1986-10-06 1991-05-28 American Biomaterials Corporation Nerve regeneration conduit
US5281226A (en) * 1989-03-31 1994-01-25 Davydov Anatoly B Missing portion of a tubular bone
US5645591A (en) 1990-05-29 1997-07-08 Stryker Corporation Synthetic bone matrix
US7722678B2 (en) * 1993-11-01 2010-05-25 Biomet Manufacturing Corp. Intramedullary compliant fixation
DE9317395U1 (de) * 1993-11-12 1994-01-05 Behr Otmar Dr Amputationsstumpf-Endoprothese
US6174333B1 (en) 1994-06-06 2001-01-16 Osiris Therapeutics, Inc. Biomatrix for soft tissue regeneration using mesenchymal stem cells
US6312467B1 (en) 1995-07-18 2001-11-06 Iowa State University Research Foundation, Inc. Method of restructuring bone
US6364909B1 (en) 1995-07-18 2002-04-02 Iowa State University Research Foundation, Inc. Method of restructuring bone
US6217620B1 (en) 1995-09-29 2001-04-17 Joon B. Park Reinforcing an orthopedic implant
IT1279721B1 (it) 1995-12-22 1997-12-16 Istituti Ortopedici Rizzoli Dispositivo protesico ortopedico
US6280473B1 (en) 1996-08-19 2001-08-28 Macropore, Inc. Resorbable, macro-porous, non-collapsing and flexible membrane barrier for skeletal repair and regeneration
CZ54899A3 (cs) 1996-08-23 1999-08-11 Cook Biotech, Incorporated Štěpová protéza, materiály s ní spojené a způsoby její výroby
US6702821B2 (en) * 2000-01-14 2004-03-09 The Bonutti 2003 Trust A Instrumentation for minimally invasive joint replacement and methods for using same
US8038708B2 (en) 2001-02-05 2011-10-18 Cook Medical Technologies Llc Implantable device with remodelable material and covering material
US6716225B2 (en) 2001-08-02 2004-04-06 Collagen Matrix, Inc. Implant devices for nerve repair
US7299805B2 (en) 2002-06-07 2007-11-27 Marctec, Llc Scaffold and method for implanting cells
US7189263B2 (en) 2004-02-03 2007-03-13 Vita Special Purpose Corporation Biocompatible bone graft material
US8568413B2 (en) * 2008-12-18 2013-10-29 Sonoma Orthopedic Products, Inc. Bone fixation device, tools and methods
US8480757B2 (en) 2005-08-26 2013-07-09 Zimmer, Inc. Implants and methods for repair, replacement and treatment of disease
ES2320829B1 (es) * 2007-02-02 2010-03-12 Tequir, S.L. Endoprotesis femoral modular.
CA2781407A1 (en) 2008-01-14 2009-07-23 Michael P. Brenzel Apparatus and methods for fracture repair
GB0813659D0 (en) 2008-07-25 2008-09-03 Smith & Nephew Fracture putty
US8512416B2 (en) * 2010-02-01 2013-08-20 Biomet Manufacturing, Llc Transdermal intraosseous device
DE102010052914B4 (de) * 2010-11-30 2012-08-30 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Endoprothese und Verwendung der Endoprothese
CN107260293B (zh) * 2011-03-29 2021-06-29 史密夫和内修有限公司 具有髓内支撑物的骨折固定系统

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
None *

Also Published As

Publication number Publication date
US9561108B2 (en) 2017-02-07
US20150216666A1 (en) 2015-08-06
EP2967875A2 (de) 2016-01-20
US9039781B2 (en) 2015-05-26
US20170042681A1 (en) 2017-02-16
WO2014150658A3 (en) 2014-12-24
US20140288662A1 (en) 2014-09-25
WO2014150658A2 (en) 2014-09-25
EP2967875A4 (de) 2016-11-16
US10219907B2 (en) 2019-03-05

Similar Documents

Publication Publication Date Title
US6364909B1 (en) Method of restructuring bone
US11833052B2 (en) Tissue integration design for seamless implant fixation
US6312467B1 (en) Method of restructuring bone
AU718801B2 (en) Resorbable, macro-porous, non-collapsing and flexible membrane barrier for skeletal repair and regeneration
US6749639B2 (en) Coated prosthetic implant
US9616205B2 (en) Drug delivery implants
US5340362A (en) Method and apparatus for cementing intramedullary bone prosthesis
US20100009103A1 (en) Medical material
WO2009105535A1 (en) Transcutaneous osseointegrated device for prostheses
JP6554166B2 (ja) オッセオインテグレーション可能な機器
US10219907B2 (en) Devices, systems and methods for elongating bone
EP2967880B1 (de) Leitungen zur verbesserung einer geweberegeneration
KR101726932B1 (ko) 치과 매식학에서의 뼈 증대
KR102636800B1 (ko) 골 내강 주사가 가능한 윈도우를 갖춘 골조직 재건용 하이브리드 인공 지지구
Saha et al. A biomechanical and histological examination of different surface treatments of titanium implants for total joint replacement
Tomaszewski et al. In-vivo experiment with the new direct fixation implant
Yumashev et al. Application of Implants and Endoprostheses Made of Domestic Carbon-Containing Materials in Traumatology and Orthopedy

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20150928

AK Designated contracting states

Kind code of ref document: A2

Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

AX Request for extension of the european patent

Extension state: BA ME

DAX Request for extension of the european patent (deleted)
A4 Supplementary search report drawn up and despatched

Effective date: 20161018

RIC1 Information provided on ipc code assigned before grant

Ipc: A61F 2/78 20060101ALI20161012BHEP

Ipc: A61F 2/28 20060101AFI20161012BHEP

GRAP Despatch of communication of intention to grant a patent

Free format text: ORIGINAL CODE: EPIDOSNIGR1

INTG Intention to grant announced

Effective date: 20170802

GRAS Grant fee paid

Free format text: ORIGINAL CODE: EPIDOSNIGR3

GRAA (expected) grant

Free format text: ORIGINAL CODE: 0009210

AK Designated contracting states

Kind code of ref document: B1

Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

REG Reference to a national code

Ref country code: GB

Ref legal event code: FG4D

REG Reference to a national code

Ref country code: CH

Ref legal event code: EP

REG Reference to a national code

Ref country code: IE

Ref legal event code: FG4D

REG Reference to a national code

Ref country code: AT

Ref legal event code: REF

Ref document number: 955666

Country of ref document: AT

Kind code of ref document: T

Effective date: 20180115

REG Reference to a national code

Ref country code: DE

Ref legal event code: R096

Ref document number: 602014018834

Country of ref document: DE

REG Reference to a national code

Ref country code: FR

Ref legal event code: PLFP

Year of fee payment: 5

REG Reference to a national code

Ref country code: NL

Ref legal event code: MP

Effective date: 20171220

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: SE

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20171220

Ref country code: NO

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20180320

Ref country code: FI

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20171220

Ref country code: LT

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20171220

REG Reference to a national code

Ref country code: LT

Ref legal event code: MG4D

REG Reference to a national code

Ref country code: AT

Ref legal event code: MK05

Ref document number: 955666

Country of ref document: AT

Kind code of ref document: T

Effective date: 20171220

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: HR

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20171220

Ref country code: GR

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20180321

Ref country code: BG

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20180320

Ref country code: RS

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20171220

Ref country code: LV

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20171220

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: NL

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20171220

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: ES

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20171220

Ref country code: CZ

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20171220

Ref country code: CY

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20171220

Ref country code: EE

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20171220

Ref country code: SK

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20171220

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: RO

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20171220

Ref country code: IT

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20171220

Ref country code: IS

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20180420

Ref country code: AT

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20171220

Ref country code: SM

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20171220

Ref country code: PL

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20171220

REG Reference to a national code

Ref country code: DE

Ref legal event code: R097

Ref document number: 602014018834

Country of ref document: DE

REG Reference to a national code

Ref country code: CH

Ref legal event code: PL

PLBE No opposition filed within time limit

Free format text: ORIGINAL CODE: 0009261

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: NO OPPOSITION FILED WITHIN TIME LIMIT

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: MC

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20171220

Ref country code: DK

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20171220

26N No opposition filed

Effective date: 20180921

REG Reference to a national code

Ref country code: BE

Ref legal event code: MM

Effective date: 20180331

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: LU

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20180312

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: LI

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20180331

Ref country code: CH

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20180331

Ref country code: SI

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20171220

Ref country code: BE

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20180331

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: MT

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20180312

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: TR

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20171220

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: PT

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20171220

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: MK

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20171220

Ref country code: HU

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT; INVALID AB INITIO

Effective date: 20140312

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: AL

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20171220

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: GB

Payment date: 20220120

Year of fee payment: 9

Ref country code: DE

Payment date: 20220118

Year of fee payment: 9

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: FR

Payment date: 20220118

Year of fee payment: 9

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: IE

Payment date: 20230110

Year of fee payment: 10

REG Reference to a national code

Ref country code: DE

Ref legal event code: R119

Ref document number: 602014018834

Country of ref document: DE

GBPC Gb: european patent ceased through non-payment of renewal fee

Effective date: 20230312

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: GB

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20230312

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: GB

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20230312

Ref country code: FR

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20230331

Ref country code: DE

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20231003

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: IE

Payment date: 20240103

Year of fee payment: 11