EP2941250A4 - Insulino-indépendance parmi des patients atteints du diabète à l'aide d'une combinaison de ppi in avec un agent de tolérance immunitaire - Google Patents
Insulino-indépendance parmi des patients atteints du diabète à l'aide d'une combinaison de ppi in avec un agent de tolérance immunitaireInfo
- Publication number
- EP2941250A4 EP2941250A4 EP13840277.1A EP13840277A EP2941250A4 EP 2941250 A4 EP2941250 A4 EP 2941250A4 EP 13840277 A EP13840277 A EP 13840277A EP 2941250 A4 EP2941250 A4 EP 2941250A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- ppi
- patients
- combination
- immune tolerance
- insulin independence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/37—Digestive system
- A61K35/39—Pancreas; Islets of Langerhans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
- A61K38/13—Cyclosporins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/21—Interferons [IFN]
- A61K38/212—IFN-alpha
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/55—Protease inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0676—Pancreatic cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/40—Regulators of development
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biomedical Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Marine Sciences & Fisheries (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Developmental Biology & Embryology (AREA)
- Virology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Materials For Medical Uses (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201361749197P | 2013-01-04 | 2013-01-04 | |
PCT/US2013/061972 WO2014052625A1 (fr) | 2012-09-27 | 2013-09-26 | Insulino-indépendance parmi des patients atteints du diabète à l'aide d'une combinaison de ppi in avec un agent de tolérance immunitaire |
Publications (2)
Publication Number | Publication Date |
---|---|
EP2941250A1 EP2941250A1 (fr) | 2015-11-11 |
EP2941250A4 true EP2941250A4 (fr) | 2016-07-27 |
Family
ID=54250581
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP13840277.1A Withdrawn EP2941250A4 (fr) | 2013-01-04 | 2013-09-26 | Insulino-indépendance parmi des patients atteints du diabète à l'aide d'une combinaison de ppi in avec un agent de tolérance immunitaire |
Country Status (2)
Country | Link |
---|---|
EP (1) | EP2941250A4 (fr) |
JP (1) | JP2016503070A (fr) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8732150B2 (en) | 2010-09-23 | 2014-05-20 | Salesforce.Com, Inc. | Methods and apparatus for suppressing network feed activities using an information feed in an on-demand database service environment |
US9063632B2 (en) | 2013-03-15 | 2015-06-23 | Salesforce.Com, Inc. | Systems and methods for interacting with records via a publisher and an information feed |
US9665261B2 (en) | 2013-10-28 | 2017-05-30 | Salesforce.Com, Inc. | Providing a user interface for customizing state transitions of panes in a bounding window |
US10198484B2 (en) | 2015-09-10 | 2019-02-05 | Salesforce.Com, Inc. | Displaying reduced and detailed visual representations of calendar items based on mouse cursor movement |
JP2019077615A (ja) * | 2016-03-09 | 2019-05-23 | 公立大学法人和歌山県立医科大学 | 非アルコール性脂肪性肝疾患/非アルコール性脂肪性肝炎の治療剤 |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2006128083A2 (fr) * | 2005-05-25 | 2006-11-30 | Curedm, Inc. | Peptides, derives et analogues associes, et leurs methodes d'utilisation |
-
2013
- 2013-09-26 EP EP13840277.1A patent/EP2941250A4/fr not_active Withdrawn
- 2013-09-26 JP JP2015551668A patent/JP2016503070A/ja active Pending
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2006128083A2 (fr) * | 2005-05-25 | 2006-11-30 | Curedm, Inc. | Peptides, derives et analogues associes, et leurs methodes d'utilisation |
Non-Patent Citations (3)
Title |
---|
BOJ-CARCELLER DIANA: "Proton pump inhibitors: impact on glucose metabolism", ENDOCRINE, vol. 43, no. 1, 12 August 2012 (2012-08-12), pages 22 - 32, XP002758860 * |
LEVETAN C: "Distinctions between islet neogenesis and [beta]-cell replication: Implications for reversal of Type 1 and 2 diabetes", JOURNAL OF DIABETES 2010 WILEY-BLACKWELL AUS, vol. 2, no. 2, June 2010 (2010-06-01), pages 76 - 84, XP002758861, ISSN: 1753-0393 * |
See also references of WO2014052625A1 * |
Also Published As
Publication number | Publication date |
---|---|
EP2941250A1 (fr) | 2015-11-11 |
JP2016503070A (ja) | 2016-02-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 20150724 |
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AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR |
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AX | Request for extension of the european patent |
Extension state: BA ME |
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DAX | Request for extension of the european patent (deleted) | ||
A4 | Supplementary search report drawn up and despatched |
Effective date: 20160629 |
|
RIC1 | Information provided on ipc code assigned before grant |
Ipc: A61K 35/39 20150101ALI20160621BHEP Ipc: A61K 31/415 20060101ALI20160621BHEP Ipc: A61P 3/08 20060101ALI20160621BHEP Ipc: A61P 3/10 20060101ALI20160621BHEP Ipc: A61K 38/17 20060101ALI20160621BHEP Ipc: A61K 9/20 20060101ALI20160621BHEP Ipc: A61K 31/4439 20060101ALI20160621BHEP Ipc: C12N 5/071 20100101ALI20160621BHEP Ipc: A61K 31/44 20060101AFI20160621BHEP Ipc: A61K 9/48 20060101ALI20160621BHEP Ipc: A61K 38/13 20060101ALI20160621BHEP Ipc: A61K 45/06 20060101ALI20160621BHEP |
|
17Q | First examination report despatched |
Effective date: 20170619 |
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STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20180103 |