EP2903583B1 - Transfer device for tapping or delivering a fluid - Google Patents

Description

• ein auf die Flasche aufsetzbares, den Verschluss umgebendes hohlzylinderförmiges erstes Teil mit Umfangswandung sowie eine quer zur Längsachse des ersten Teils verlaufende zweite Wandung,
• ein zu dem ersten Teil verstellbares hohlzylinderförmiges zweites Teil mit einer quer zur Längsachsenrichtung verlaufenden ersten Wandung,
• eine von der ersten Wandung ausgehende und in Richtung des ersten Teils sich erstreckende ein Durchstechen des Verschlusses ermöglichende Punktionsnadel,

wobei bei fehlendem Umgeben des Verschlusses (Zustand vor Nutzung) das erste Teil axial oder im Wesentlichen axial unverstellbar zu dem zweiten Teil ist und distales Ende der Punktionsnadel zwischen der ersten und der zweiten Wandung verläuft und bei den Verschluss umgebenden ersten Teil das erste Teil zu dem zweiten Teil zum Durchstechen des Verschlusses verstellbar ist.The invention relates to a transfer device for withdrawing or transferring a fluid from a bottle closed via a closure, comprising

• a hollow cylinder-shaped first part with peripheral wall which can be placed on the bottle and surrounds the closure, and a second wall extending transversely to the longitudinal axis of the first part,
• a hollow-cylindrical second part which can be adjusted to the first part and has a first wall running transversely to the longitudinal axis direction,
• a puncture needle, which extends from the first wall and extends in the direction of the first part, permitting puncture of the occlusion,

wherein in the absence of surrounding the closure (state before use), the first part is axially or substantially axially immovable to the second part and the distal end of the puncture needle between the first and the second wall extends and surrounding the closure of the first part of the first part to the second part for piercing the closure is adjustable.

Many medications for infusion and injection are delivered as dry substances and mixed with water or other solvent into a solution or suspension shortly before use / administration. The dry substance is usually delivered in an injection vial, a so-called vial. Also primarily liquid medicines are offered in vials. To connect this bottle to another container or infusion device, a connector (transfer device) is needed, into which the head of the vial is forced and the membrane of the vial is perforated. The other container may be another injection bottle, an infusion bag or a syringe.

According to the prior art, these connectors, which are also referred to as adapters, can have in the center a steel cannula or a plastic mandrel which is surrounded by a collar forming a hollow cylindrical body which snaps onto the flange-shaped edge with the crimp cap of the vial, in particular consisting of aluminum. From the bottom wall of the collar, the puncture needle goes out in particular in the form of the steel cannula and extends in the longitudinal direction of the hollow cylindrical body.

Such adapters no longer meet today's requirements for vial adapters, for two reasons. On the one hand, the accident prevention regulations TRBA 250 and a corresponding European directive require the safety of such products. If such vial adapter provided with a steel cannula, the former are not injury-resistant, since the diameter of the hollow cylindrical adapter, ie collar, is large enough to penetrate into this with a finger and thus there is a risk of injury through the cannula.

The second reason is that the plug must be punctured centrally by the puncture needle to ensure leak-tight connection of the vial. However, in the prior art vial adapters, there is a risk that the vial will tilt when snapped into the collar. This results in a primarily eccentric puncture of the plug. During the subsequent complete pushing in of the vial, the cannula is then forced into a centric position. This leads to the tension of the vial plug, which can lead to leaks next to the cannula. This can be toxic substances such. As cytostatics, to endanger personnel and patients.

A transfer device of the type mentioned is the EP 1 430 864 B1 refer to. The transfer device consists of a cap-like outer guide member and a tubular inner guide member which are telescopically displaceable to each other. In the unused state, the origins of the inner guide part snap into recesses of the outer guide part that run on the inside. When the transfer device is slid onto a vial, tongue-like elements emanating from the inner guide part are bent outward, with the result that the outer guide part is displaced outwards in the region of the recesses, so that the latching between the inner and outer guide parts is released. Regardless, the puncture needle, which emanates from the outer guide part, in the delivery state over the opening of the inner guide member freely accessible, so that the same risk of injury exists as in transfer devices, which are integrally formed.

From the DE 10 2005 006 771 A1 For example, a transfer device is known which comprises a needle holder with transfer needle that is axially adjustable in a hollow cylindrical structure. The Structure has a wall-shaped stopper, which can be placed on the opening of a storage container to be pierced and is penetrated by the transfer needle during actuation of the transfer device.

A transfer device according to the DE 698 08 432 T2 has an actuator to axially adjust a mandrel having a first part to a closure surrounding a bottle surrounding the second part.

Of the WO 2011/140596 A1 is a transfer device can be seen, which comprises a first and a second hollow cylindrical part, wherein in unused transfer device, a puncture needle between two walls, so that the tip is not detectable. When the transfer device is pushed onto a bottle, the first part is adjustable relative to the puncture needle, with the result that the puncture needle can pass through the first part in order to perforate the closure of the bottle.

A three-piece transfer device is from the EP 0 311 787 A2 known. The parts are slidable relative to one another to ensure locking of the transfer device about a closure, and secondly to restrict a displaceability of an inner part covering the tip of a cannula prior to disuse of the transfer device in its axial movement such that the cannula has a plug held by the inner part can not enforce.

A transfer device according to the EP 1 430 864 B1 has telescopically displaceable cylindrical parts. The cannula-containing outer member is then slidable to the vial-enclosing inner portion as it surrounds the occlusion plug of the vial.

The EP 1 574 200 A1 refers to a transfer needle assembly and comprises a bearing body penetrated by a needle, the ends of which are adjustable within tubular housings, which in turn are closed at the end by covers which are to be perforated. To make this possible, a sleeve surrounding both the bearing body and the tubular housing is provided, by means of which the tubular housings are adjusted to the bearing body and thus to the needle in such a way that the lids are pierceable successively.

A transfer device according to the WO 00/47159 A1 has a base member with in this axially displaceable piston with outgoing therefrom puncture needle. The piston is surrounded by a removable sleeve with cap to axially adjust the piston for penetrating a closure can. In the unused state, the tip of the puncture needle is freely accessible. Upon the need to penetrate a closure of a bottle, the piston receiving the puncture needle may engage the base member so that retraction is not possible.

The object of the present invention is to provide a transfer device, that is to say a vial connector or adapter, which is particularly resistant to injury. It is also to be ensured according to a further aspect that when unlocking the adapter parts, a removal of the first part of the second part or a withdrawal of the second part of the first part is no longer possible. Also, if possible, the possibility should be created that when puncturing the occlusion of the vial, an expulsion of fluid parts or aerosols from the vial is prevented.

According to the invention, the object is essentially achieved in that at least one lever element extends from the peripheral wall of the first part with a first section extending in the direction of the second part and a second section extending in the direction of the bottle side opening of the first part Unadjustability or substantially unadjustability between the first and second part to each other, the first portion projects laterally outwardly beyond the peripheral wall of the first part and the second Section projects into the interior of the first part, the first portion with the second part for preventing the adjustment of the first part to which interacts the second part and in which the closure of the bottle surrounding the first portion of the second portion of the at least one lever element is adjusted radially outward while simultaneously reaching the first section with the second part, or
in that the second part of slits extending in the longitudinal direction of the second part has tongue-shaped elements with protrusions projecting into the interior of the second part, that the protrusions in axial or substantially axial unobstructability between the first and the second part in present in the first part engages below the second wall extending recesses, which have a distance from the lower edge of the first part such that when the first part surrounds the bottle locked, the projections by interacting with the bottle into reach with the recesses and penetrated in the closure Puncture needle the projections flange behind the lower edge of the first part.

Characterized in that the inner or first part in its open-area region has a second wall called the intermediate or bottom wall and is latched first and second part of the tip of the puncture needle of the intermediate wall of the first part and circumferentially surrounded by the peripheral wall of the second part, It is ensured that a risk of injury is excluded even if a finger gets into the interior of the first part.

Thus, when adjusting the first to the second part, the perforation of the closure, which according to the prior art is basically a consisting of aluminum and flanged around the flange edge of the vial membrane is not affected, it is provided that the second wall in the axial extension the puncture needle is broken.

In order to ensure with structurally simple measures that, if no vial is inserted into the transfer device, an unadjustability or substantially unadjustability between the first and second part is given, even if relatively large axial forces act on the transfer device is provided according to the invention that from the peripheral wall of the first part, one or more preferably tongue-like lever elements emanate with each one in the direction of the second part extending first portion and extending in the direction of the bottle side opening of the first part second portion, wherein in the case of the axial or substantially axial unadjustability between the first and second parts relative to one another, the first sections protrude laterally beyond the peripheral wall of the first section and the second sections protrude into the interior of the first section, the first sections with the second Te il for preventing the displacement of the first part in the second part interact, and in the closure of the bottle in particular latched surrounding the first part, the second portions of the lever elements are radially outwardly adjusted at the same time Inausgriffgelangen the first portions with the second part.

Tongue-like levers extending from the first part are used to prevent adjustability of the first part to the second part unless a vial is inserted into the first part and the first part is locked to the flange-like edge of the vial. Since the lever elements in the longitudinal direction of the transfer device, so the connector extend, they can absorb large forces without the risk of uncontrolled pivoting occurs. If the transfer device is pushed onto a vial, then the second or inner sections of the lever elements slide along the peripheral surface of the closure and are thereby pivoted radially outwards, with the result that the first or outer sections of the lever elements are pivoted radially inward and thus in reach get to the second part holding the puncture needle. Then there is the possibility that the required relative position between the first and second part takes place and thus the puncture needle can perforate the closure. At the same time an exact axial guidance is given, which ensures a central perforation of the closure, since the first part is guided axially to the second part.

In order to enable the axial adjustment of the first part, ie the bottle or Vialhalter, to the second part, ie the puncture needle or needle holder, a telescopic displacement of the parts to each other or a rotation of these can be performed to each other. During the rotation, an axial adjustment of the first part to the second part likewise takes place in order to displace the puncture needle in the direction of the vial and to penetrate its closure.

In order to preclude a loosening of the first of the second part is provided in particular that the first and the second part in the axial or substantially axial unadjustability between the first and second part are latched to each other, preferably emanating from the inside of the peripheral wall of the second part Protrusions engage in recesses of the peripheral wall of the first part.

According to a self-inventively embodiment likewise to be emphasized, it is further provided that the first part is fundamentally adjustable to the second part exclusively in the direction of penetration, that is, withdrawal is not possible. For this purpose, provision is made in particular for the peripheral wall of the first part to have depressions spaced apart from one another in the axial direction for stepwise locking of the projections. There is thus provided a kind of tooth lock which allows easy insertion of the first part into the second part, ie the inner part into the outer part, but prevents retraction.

Other technical solutions, which also ensure that the first part can be adjusted in the direction of the vial without allowing retraction, are also covered by the invention.

In other words, the invention is also characterized by a transfer device for removing or transferring a fluid from a bottle closed via a closure, comprising a hollow-cylindrical first part with circumferential wall which can be placed on the bottle and surrounds the closure, a hollow-cylindrical second which can be adjusted to the first part Part with a transverse to the longitudinal axis direction of the first wall, one of the first wall outgoing and extending in the direction of the first part, a piercing of the closure enabling Puncture needle, the first part with the second part in their adjustment to each other in the axial direction interact with each other such that the second part is exclusively or substantially exclusively in the direction of penetration to the first part adjustable, thus retraction is prevented.

The relevant solution can of course also be combined with other features of the transfer device.

In order to enable a guided rotation of the first to the second part to its axial adjustability, the invention provides in particular that in one of the parts along the peripheral wall and about the longitudinal axis of the part a spirally extending contour is formed like a strip-shaped projection, with a from the other part, in particular from its peripheral wall, outgoing element such as tongue interacts. In this case, the contour may have a sawtooth-like profile and the element interacts with the contour projection such as hooks, wherein an interaction takes place such that unimpeded rotation of the first part to the second part takes place exclusively in the penetration direction of the puncture needle. By this measure, it is ensured that an axial adjustment of the first part in the second part, ie the Vialhalters in the needle holder is possible, ie the puncture needle is adjusted in the direction of the vial, but not vice versa.

In particular, it is provided that the contour protrudes beyond the outer peripheral surface of the first part, that the inner peripheral surface of the second part has at least one recess adapted at least in sections to the contour of the contour, in which the contour is guided. Thus, even with a small length of the connector ensures that a perfect axial adjustment is possible to each other.

In order to ensure that the first part, ie the vial holder, is not rotated during rotation of the needle holder, ie the second part, it is further provided that a handle extends from the first part, in particular two diametrically opposite one another and from the first part projecting wings, by means of which the first part of the bottle, so the vial is fixable.

According to the invention, it is provided that the second part of slits extending in the longitudinal direction of the second part has tongue-shaped elements with protrusions projecting into the interior of the second part, that the protrusions between the first and the second part in the axial or substantially axial unobstructability engaging in recesses provided in the first part which are spaced from the lower edge of the first part such that, when the bottle is latched from the first part, the protrusions interact with the recesses with the bottle or with an outgoing therefrom. In this case, provision is made in particular for the projections to be ramp-shaped or wedge-shaped in their free ends in such a way that an obliquely extending surface to the longitudinal direction slides along the bottle or its edge.

Furthermore, the invention provides that the opening-side edge of the first part has inwardly projecting projections for grasping a flange-like edge surrounding the opening of the bottle, wherein unlocking between the first portions of the lever elements and the second part before grasping the flange-like edge is omitted. By grasping, the first part snaps onto the vial, i. H. its flange-shaped edge.

The intermediate wall, which virtually shields the tip of the puncture needle when the transfer device is unused, is brought into contact with the first part on the outside of the closure when the first part is inserted into the second part or the second part is pushed onto the first part, so that the required power transmission is made possible to move the first part to the second part.

In order to ensure that aerosols can not be released when puncturing the closure in the case of toxic substances, it is provided in a further inventive design that an element extending in the axial extension of the puncture needle emanating from the second wall pierces the puncture needle peripherally sealing element such as membrane or plug. The corresponding elements are in particular those made of elastomeric material, which is punctured by the puncture needle and simultaneously pressed against the closure of the vial. The corresponding elements such as membrane or plug then seal the puncture needle circumferentially. At the same time a sealing against the Outside of the lock. This ensures that the contents of the vial can not escape when piercing the components.

According to the invention a two-piece connector cap is provided, wherein the parts are arranged telescopically against each other and mutually adjustable. The inner or first part has barbs for snapping the vial head and the outer or second part has the puncture needle for perforating the closure of the vial. In the delivery position of the vial, the inner part protrudes from the outer part, wherein the tip of the cannula is protected behind the wall of the inner or first part to be designated as the bottom. Thus, even if a user accidentally engages the interior of the connector or adapter, injury to the puncture needle tip is excluded. So that the inner part can not be pressed into the outer part before the connection with the vial, lever-like locking devices are provided in the circumference of the inner part, which prevent the inner part can be pushed into the outer part. Only with complete insertion of the vial head into the inner part, the locking levers are pushed outwards by the vial head. They pivot about an axis, so that in the direction of the outer part extending end, which otherwise locks the insertion of the inner part into the outer, is pivoted inwards and thus the way for the adjustment as insertion or screwing of the inner part in the outer part of the vial adapter releases. When the inner part is fully inserted in the outer part to the required extent, there is a permanent locking with the outer part. During this adjustment as insertion or rotation process, the puncture needle punctures the closure, so the diaphragm of the vial stopper.

So that it can not happen that the inner part is half inserted, the cannula already perforated the membrane and then the vial is withdrawn with the first part again, so that could emerge into the cannula entered substances, it is provided in particular that on the outside of the inner part a toothed lock is attached, which allows a slight insertion of the inner part in the outer part, but no retraction. Alternatively, this ensures the spiraling contour with the sawtooth-like profile.

Since it may be important that no aerosols are released in toxic substances when puncturing the membranes, elastomeric components can be arranged in the inner wall of the inner part, which are punctured by the puncture needle and simultaneously pressed against the outside of the closure of the vial. These components seal both around the cannula and against the occlusion of the vial, so that when piercing the substances from the vial can not escape into the open.

All of these previously explained measures have their own inventive content.

Further details, advantages and features of the invention will become apparent not only from the claims, the features to be taken - alone and / or in combination - but also from the following description of a preferred embodiment of the drawings.

Fig. 1

eine erste Ausführungsform einer Transfervorrichtung, teilweise geschnitten, im verriegelten Zustand,

Fig. 2

die Transfervorrichtung gemäß Fig. 1 vor der Entriegelung,

Fig. 3

die Transfervorrichtung nach den Fig. 1 und 2 nach der Entriegelung,

Fig. 4

die Transfervorrichtung nach den Fig. 1 bis 3 vor der Penetration,

Fig. 5

die Transfervorrichtung nach den Fig. 1 bis 4 in der Endlage,

Fig. 6

eine zweite Ausführungsform einer Transfervorrichtung,

Fig. 7

eine dritte Ausführungsform einer Transfervorrichtung,

Fig. 8

eine vierte Ausführungsform einer Transfervorrichtung vor Penetration eines Verschlusses,

Fig. 9

die Transfervorrichtung gemäß Fig. 8 während der Penetration,

Fig. 10

die Transfervorrichtung nach Fig. 8 und 9 am Ende der Penetration,

Fig. 11

eine Seitenansicht eines ersten Teils der Transfervorrichtung gemäß Fig. 8 bis 10,

Fig. 12

das erste Teil gemäß Fig. 11 in Draufsicht,

Fig. 13

eine Seitenansicht eines zweiten Teils der Transfervorrichtung gemäß Fig. 8 bis 10,

Fig. 14

einen Schnitt durch das zweite Teil gemäß Fig. 14,

Fig. 15

einen Ausschnitt des ersten und zweiten Teils,

Fig. 16

eine sechste Ausführungsform einer Transfervorrichtung ohne Flasche,

Fig. 17

die Transfervorrichtung nach Fig. 16 in einer teilweise auf eine Flasche aufgeschobener Position,

Fig. 18

die Transfervorrichtung nach den Fig. 16 und 17 in entsicherter Stellung,

Fig. 19

die Transfervorrichtung nach den Fig. 16 bis 18 nach teilweiser erfolgter Penetration des Flaschenverschlusses und

Fig. 20

die Transfervorrichtung nach den Fig. 16 bis 19 in ihrer Endstellung, jedoch ohne Flasche.

Show it:

Fig. 1

a first embodiment of a transfer device, partially cut, in the locked state,

Fig. 2

the transfer device according to Fig. 1 before unlocking,

Fig. 3

the transfer device after the Fig. 1 and 2 after unlocking,

Fig. 4

the transfer device after the Fig. 1 to 3 before the penetration,

Fig. 5

the transfer device after the Fig. 1 to 4 in the final position,

Fig. 6

A second embodiment of a transfer device

Fig. 7

A third embodiment of a transfer device,

Fig. 8

A fourth embodiment of a transfer device before penetration of a closure,

Fig. 9

the transfer device according to Fig. 8 during the penetration,

Fig. 10

the transfer device after Fig. 8 and 9 at the end of the penetration,

Fig. 11

a side view of a first part of the transfer device according to Fig. 8 to 10 .

Fig. 12

the first part according to Fig. 11 in plan view,

Fig. 13

a side view of a second part of the transfer device according to Fig. 8 to 10 .

Fig. 14

a section through the second part according to Fig. 14 .

Fig. 15

a section of the first and second part,

Fig. 16

A sixth embodiment of a transfer device without a bottle,

Fig. 17

the transfer device after Fig. 16 in a partially deferred position on a bottle,

Fig. 18

the transfer device after the Fig. 16 and 17 in the unlocked position,

Fig. 19

the transfer device after the Fig. 16 to 18 after partial penetration of the bottle cap and

Fig. 20

the transfer device after the Fig. 16 to 19 in its final position, but without a bottle.

In the figures, in which basically the same elements are provided with the same reference numerals, transfer devices are shown, by means of which of a bottle or vial, a so-called vial, fluids such as dry substances or liquids such as water or solvent for infusion or injection purposes be mixed before their application or administration. Corresponding transfer devices are also referred to as connectors or adapters. In order to connect the bottle with another container or an infusion device, a corresponding transfer device is required to puncture by means of a puncture needle - such as steel cannula - the closure of the vial, and then via the transfer device, the vial to be removed fluid z. B. an injection bottle, an infusion bag or a syringe to be able to perform.

The transfer devices to be taken from the figures have telescopically arranged and mutually adjustable parts, which are referred to as first and second part or inner or outer part. For the sake of simplicity, the transfer device will hereinafter be referred to as a connector and the vial to be connected to it as a vial. The first part is also called Vialhalter and the second part as a cannula holder.

With regard to the specified geometries of the components, it should be noted that these are purely exemplary in that deviations are also possible, provided that the basic principles of the invention can be realized. Incidentally, the figures are self-explanatory. In these, the characteristics of the invention are clearly visible.

The Fig. 1 to 5 shows a first embodiment of a connector 10, which is composed of an inner or first part 12 and a second or outer part 14, which are arranged telescopically to each other and axially displaceable to each other. The inner part 12 and the outer part 14 is in particular an injection molded part and consists of a suitable plastic.

The inner part 12 has a peripheral wall 16 which has a hollow cylindrical shape and comprises tongue-like and thus movable sections 18 which are peripherally bounded by slots and have projections 20 projecting inward in their free ends in order to engage behind a flange-like edge 22 of a vial 24 in the use position. as can be seen from the Fig. 4 and 5 results. In the usual way, the flange-like edge 22 is an opening of the vial 24, which is closed by a sealing plug 26.

Typically, after sealing the vial 24 with the stopper 26, an aluminum crimp cap is applied. On this can be a flip-off cap made of plastic. This flip-off cap is pulled off the aluminum crimp cap so that a "hole" is created in the center of the aluminum crimp cap so that the stopper 26 is visible. This preparation for opening the aluminum crimp cap, hereinafter referred to as membrane 28, is typically performed prior to piercing with a cannula since the plastic flip-off cap must be removed. In that regard, reference is made to well-known constructions.

The inner or first part 12 furthermore has, at a distance from the latching projections 20, an intermediate wall 30, which runs transversely to the longitudinal axis of the first part 12 and is referred to as a second wall, which is also referred to as a bottom wall, the same way web-like sections of the circumferential wall 16 extend over the intermediate wall. or bottom wall 30 extend in the direction of the second part 14, as the drawings illustrate. Further, it is apparent from the illustrations that the outside of the peripheral wall 16 has a sawtooth-like notch 32 to serve as barbs for explanatory projections of the outer or second part 14 hereinafter.

From the inner part 12 are preferably uniformly distributed over the circumference of the peripheral wall 16 tongue-like lever members 34, 36 which are connected to the bottom wall 30 and are radially pivotable about an axis perpendicular to the longitudinal axis of the connector 10 extending axis. Each lever element 34, 36 - also called lever - thus consists of a first or outer portion 38 and a second or inner portion 40, wherein in the ground state, ie when the levers 34, 36 no radial forces act, the outer portion 38th partially protrudes laterally beyond the outer surface of the peripheral wall 16, whereas the inner portion 14 protrudes with its hook-shaped end 42 in sections into the interior of the first part 12.

The outer or second part 14 likewise has a circumferential wall 44 which forms a hollow cylinder geometry and is delimited by a bottom wall 46 to be designated as the first wall, of which on the one hand a cannula 48 extending in the longitudinal axis direction of the connector 10 in the direction of the first part runs in opposite directions a so-called break-off connector 50 goes out, which consists of plastic and in which the cannula 48 is glued. The break-off connector 50 has a thinned predetermined breaking point 52 to break the tip 54 when the connector 10 is used. In that regard, reference is also made to known constructions.

It also follows from the drawings that the first wall or bottom wall 46 has a flange 55 protruding beyond the circumferential wall 44 or a flange-like handle, so that, basically, a hat geometry results for the second part 14.

In the peripheral wall 44 of the outer part 14, also preferably distributed uniformly around the circumference, provided by slots tongue-like portions 56, 58 are present, which have hook-shaped projections 60 in their free ends to lock with the inner part 12 can. The projections 60 protrude upon delivery of the connector 10 in above the second wall 30 projecting and in extension of the peripheral wall 16 extending web-like portions 62, 64 existing recesses (detent recesses) 66, 68 latching. This ensures that the inner part 12 can not be pulled out of the outer part 14 in order to release the parts 12, 14.

In the delivery state of the connector 10, as this in principle the Fig. 1 can be seen, the outer part 14 is supported on the outer portions 38 of the tongue-like lever members 34. For this purpose, engage the end portions of the outer portions 38 in corresponding recesses 70 in the peripheral wall 44 of the outer member 14 so that viewed in the axial direction, the upper boundaries 72 of the recesses 70 on the outer portions 38 of the lever members 34, 36 rest. At the same time engage the locking projections 16 of the tongue-like pivotable portions 56, 58 of the peripheral wall 44 of the outer part 14 in the locking receptacles 66, 68 of the web-like portions 62, 64 of the inner part 12 a. In this position, the distal end, ie the tip 74 of the cannula 48, extends between the bottom wall 30 of the inner part 12 and the bottom wall 46 of the outer part 14, so that notwithstanding the fact that the bottom wall 30 has an opening 76 in this area, a risk of injury to a user does not exist if his fingers should happen to get into the interior of the inner part 12 of the connector 14. In the drawing, the distal end extends within the bottom wall 30 of the inner part 12. In that regard, this position of the invention is understood or grasped by the invention that the distal end between the bottom walls 30, 46, as the first wall and the second wall is positioned.

In the Fig. 1 is placed in the delivery state for emptying the vial 24 of the connector 10 on the edge 12. Then there is a relative movement between the vial 24 and the connector 10, without a relative movement between the inner and outer part 12, 14 takes place, such as a comparison of Fig. 1 and 2 busy; because the inner part 12 can not be pushed into the outer part 14, as this is prevented by the lever members 34, 36, since these are supported with their outer portions 38 at the boundary of the recess 70, ie on the wall 72.

In the Fig. 2 the position is shown in which the connector 10 is close to unlocking. In this position, the locking projections 20 of the tongue-like portions 18 of the peripheral wall 16 do not yet underline the underside 78 of the edge 22 of the vial 24.

In the Fig. 3 At the same time the lever elements 34, 36 are pivoted, since the projection 42 along the peripheral surface of the edge 22 of the vial 24 is guided along with the result that thereby pivoting of the left in the drawing shown levers 34 is clockwise. In other words, the clear distance between the projection 42 of the lever 34 in the basic position of the connector 10 (FIG. Fig. 1 ) to the central axis 80 of the connector 10 is less than half the diameter of the edge 22 of the vial 24, with the result that by interaction of the projection 42 with the peripheral surface of the rim 22, the desired pivoting of the lever 34 is made possible. The vial 24 is according to the representation of Fig. 4 pushed into the inner part 12 until the membrane 28 of the closure of the vial 24 on the second wall, so the bottom wall 30 abuts, like the Fig. 4 clarified. In this position, the cannula 48 does not perforate the membrane 28 yet. If the vial 24 with the inner part 12 is then displaced into the outer part 14, the tip, that is to say the distal end 74 of the cannula 48, penetrates the membrane 28 or its hole. At the same time, the locking projection 60 of the tongue-like portions 56, 58 of the peripheral wall 44 of the outer part 14 comes into engagement with the locking receptacles 66, 68 and slides along the peripheral surface of the Peripheral wall 16 and can gradually lock with the sawtooth projections 18. This has the advantage, if a tensile force between the inner part 12 and the outer part 14 of the connector 10 would occur, the inner part 12 can not be pulled out of the outer part 14, since the locking projections 66, 68 with the sawtooth-like projections 16 in Art of barbs interact.

In the Fig. 5 the final state is shown, ie the cannula 48 with its tip 74 has penetrated into the vial 24 to the required extent. At the same time latch the locking projections 60 in locking recesses 82 in the peripheral wall 16 of the first part 12, so that a release between the inner and outer part 12, 14 is no longer possible. Also, in this position, like this one Fig. 5 can be seen, a bending away of the tongue-like portions 18 of the peripheral wall 16 radially outward no longer possible, so that a release of the vial 24 is excluded. In the end position according to the Fig. 5 Furthermore, the end region of the outer section 38 of the lever elements 34 engages in corresponding recesses 84 of the bottom wall 46 of the outer part 14. Thus, the lever member 34 can be formed relatively long, without resulting in the height and thus the compactness of the connector 10 disadvantages.

The embodiments of the Fig. 6 and 7 differ from those of Fig. 1 to 5 to the effect that elements consisting of an elastomer material in the form of a hat-shaped membrane 86 (see FIG. Fig. 7 ) or a plug 88 ( Fig. 6 ), which are pierced by the cannula 48, ie its tip 74, before penetrating the membrane 28 of the closure of the vial 24, wherein the elements 86, 88 on the one hand tightly around the cannula 48 and on the other hand a seal against the membrane 28th allow with the result that when piercing the membrane 28 contents of the vial 24 can not escape to the outside. This is particularly advantageous if there are 24 toxic substances in the vial.

Another preferred embodiment of a connector 100 is the Fig. 8 to 15 refer to. The structure and operation of the connector 100, in particular with respect to the possibility of the inner or first part 12 to adjust to the second or outer part 14, when the inner part 12 on the vial 24, ie on the edge 22, is latched, reference is made to the features and explanations described above. Also, the same reference numerals are used for the same elements in principle.

Notwithstanding the embodiment of the Fig. 1 to 7 an adjustment of the first part 12 to the second part 14 is not by an axial displacement to each other, but by a rotational movement of the first part 12 to the second part 14. This also results in a telescopic adjustment of the first to the second part 12, 14 along the Longitudinal axis 118 of the connector 100, so that the tip 54 of the cannula 48 can penetrate the membrane 28. At the same time it is ensured that a rotation of the first and second parts 12, 14 is possible only in one direction, in the penetration direction. An opposite rotation is prevented, so that the same security results, as has been explained in connection with the previously described embodiments. This also applies to the function of the lever members 34, 36, emanating from the inner or first part 12 and prevent rotation of the second part 14 to the first part 12 until the first part 12 is locked on the closure plug 26 of the vial 24 ,

In order to allow an axial adjustment of the inner part 12, so the vial holder, to the outer part 14, the needle holder, according to the embodiment of the Fig. 8 to 16 a rotational movement between the inner and outer parts 12, 14 is performed. For this purpose, the inner part 12 has a spiral-shaped contour 102, which starts from the peripheral wall 16 of the inner part 12 and thus projects beyond its circumferential outer surface 116. The spiral-shaped contour 102, which may have a strip-shaped course, thus forms a screw thread or a portion of such, as can be seen in particular from Fig. 11 results. This contour 102 is interrupted in the region of the slots which delimit the sections 18 and the lever elements 34, 36. This is done by the Fig. 11 equally clear. Instead of a screw can also be provided several screw threads.

The contour 102 extending coaxially with the longitudinal axis 118 of the vial mount has a sawtooth structure for latching engagement with a tongue-like element 120 which is cut free in the circumferential wall 44 of the outer part 14 and has one or more projections 122 extending in the direction of the contour 102, the one or more with the sawtooth profiling of the contour 102 such cooperate, that in the embodiment, the outer part 14 can be rotated exclusively in a clockwise direction, whereby the cannula 48 is adjusted in the direction of the sealing plug 26 in order to pierce the membrane 28 can. A counterclockwise rotation is not possible since in this case the hook-shaped projection 122 engages with correspondingly geometrically aligned projections of the sawtooth-shaped profiling of the contour 102.

As can be seen from the sectional views of the Fig. 8 to 10 results, the screw thread or a portion of such a following contour 102 extends within a matching recess 124 in the peripheral wall 44 of the outer member 14, which thus forms a guide during the rotational movement.

Of course, the contour of the second part and the element of the first part can go out. Such a construction is also covered by the invention.

As can be seen in particular from the Fig. 12 , protrude from the vialseitigen edge of the peripheral wall 16 of the inner part 12 from diametrically opposed wing-like elements 130, 132 which serve as a handle to fix the latching of the inner part 12 on the closure plug 26 the former to the vial 24 and the sealing plug 26 to allow the desired relative rotational movement between the inner and outer members 12, 14. In order to facilitate the rotation of the outer part 14 to the inner part 12, projecting from the peripheral wall 44 of the outer part 14 radially from a handle 136.

A comparison between the Fig. 8 to 10 illustrates that depending on the rotational position of the outer part 14 to the inner part 12, the cannula 48 is adjusted in the direction of the sealing plug 24. In the Fig. 8 the position is shown in which the outer portions 38 of the lever members 34, 36 are pivoted inwardly, so that a rotation of the outer member 14 to the inner part 12 is possible. In other words, the starting position is shown in which a rotation of the outer part 14 to the inner part 12 can take place in order to adjust the cannula 48 in the direction of the diaphragm 28 axially. In the Fig. 9 the outer part 14 has been adjusted relative to the inner part 12, so that already the membrane 28 is pierced by the tip 54 of the cannula 48. Fig. 10 reflects the end position at which the cannula 44 in desired extent the membrane 28 has penetrated. At the same time a locking of the outer part 14 with the first part 12 is possible in this position.

The Fig. 16 to 20 FIG. 2 shows a further embodiment to be emphasized of a transfer device 200 which obeys the teaching according to the invention. Therefore, according to the Fig. 1 to 15 basically the same reference numerals are used for the same elements.

The transfer device hereinafter referred to as connector 200 thus consists of the inner or first part 12 and the outer or second part 14, which are axially displaceable to each other. To ensure that when the connector 200 does not properly surround the rim of the bottle (vial 24), ie the inner or first part 12 does not cover the bottom 78 of the rim 22 of the vial 24, it will move axially between the first and second Part 12, 14 and thus a penetration of the tip 74 of the cannula 48 through the opening 76 in the second wall 30 of the first or inner part 12 is omitted, the second or outer part 14 has a plurality of preferably uniformly circumferentially distributed tongue-shaped resilient elements limited by slots 202 , 204, hereinafter referred to as tongues. The tongues 202, 204 have in their ends inwardly, ie in the direction of the central axis 80 of the connector 200 extending latching projections 206, 208, which may have a wedge or ramp-shaped geometry. In order to prevent an axial displacement of the inner part 12 to the outer part 14 in case of improper fixing of the connector 200 to the vial 24, the locking projections 206, 208 protrude into corresponding recesses 210, 212 in the peripheral wall of the inner part 12. Upon pressurization of the outer part 14 in the direction of the inner part 12 are the locking projections 206, 208 with their free perpendicular to the axis 80 extending outer surfaces 214, 216 on lower edges 218, 220 of the recesses 210, 212, whereby an axial displacement of the first and second part 12, 14 to each other is prevented. In this way it is ensured that the tip 74 of the cannula 48 remains in the intermediate space between the second wall 30 of the first part 12 and the outer boundary wall or first wall 46 of the second part 14, which is also to be referred to as an intermediate wall, thus precluding a risk of injury. If the connector 200 is pushed onto the vial 24, then the latching projections 206, 208 remain in the recesses 210, 212 of the inner part 12 until the inwardly directed projections 20 of the first part 12 behind the lower edge of the flange-like edge 22 of the vial 24. The same applies if, instead of the flange-like edge 22, another element enabling a fixing of the connector 200 is covered.

In Fig. 17 is shown a position in which the first part 12 with the free edge of the inwardly projecting projections 20, the bottom of the edge 22 of the vial 24 or a Vial 24 surrounding closure covers. As a result, the locking projections 206, 208 are bent with the spring-like tongue elements 202, 204 by cooperation with the top or the upper corner of the edge 22 to the outside, like the Fig. 18 clarified.

In order to ensure this, the distance between the recesses 210, 212 to the latching projections 20 of the first part 12 engaging behind the underside of the edge 22 of the vial is selected such that, when the first part 12 is properly fixed to the vial 24, the latching projections 206, 208 of the second part 14 along the peripheral upper edge of the flange-like edge 22 can slide when acting on the second part 14, a force in the direction of the first part 12. It thus reach the locking projections 206, 208 in a circumference in Ausgriff with the locking recesses 210, 212, that an axial displacement of the first to the second part 12, 14 is no longer prevented and thus the cannula 48 with its tip 74 in the direction of Closure stopper 26 and thus the membrane 28 occluding these can be adjusted in order to be able to pierce them on further axial displacement of the first part 12 to the second part 14. The beginning of the penetration is in the Fig. 19 recognizable. If a further displacement of the inner part 12 to the outer part 14, the latching projections 206, 208 along the outside of the first part 12 are displaced until the latching projections 206, 208 due to the resilient properties of the tongue elements 202, 204, the lower edge of the first Part 12, like this Fig. 20 can be seen in which the vial 24 is not shown in the drawing.

Thus, the connector 200 fulfills the requirement that in the unused state or in the case of incorrectly surrounding the vial 24, the cannula 48 with its tip 76 is not freely accessible, ie a risk of injury is ruled out. Only when the first part 12 properly surrounds the closure region of the vial 24, a unlocking and thus activating the connector 200 is such that an axial adjustment between the first and second part 12, 14 is made possible and thus the cannula 48 can be adjusted in the direction of the membrane 28 of the sealing plug 26 for penetrating this, as can be understood from the Fig. 16 to 20 it can be seen that are self-explanatory in this respect.

It should also be noted that in the embodiment of the Fig. 16 to 20 - As in the previous - also constructive given the possibility that the second part 14 to the first part 12 during axial displacement such locked, that a pulling apart, ie an adjustment of the first to the second part 12, 14 against the penetration direction of the cannula 48 is not possible.

LIST OF REFERENCE NUMBERS

10

Connector, transfer device

12

first (inner part)

14

second (outer) part

16

Peripheral wall of 12

18

section

20

projections

22

edge

24

Vial, bottle

26

sealing plug

28

membrane

30

second wall

32

scanning

34

lever member

36

lever member

38

outer section

40

inner section

42

The End

44

Peripheral wall of 14

46

first wall

48

cannula

50

Break-off connector

52

Breaking point

54

top

55

flange

56

section

58

section

60

head Start

62

section

64

section

66

recess

68

recess

70

recess

72

limitations

74

top

76

perforation

78

bottom

80

central axis

82

locking recesses

84

recess

86

membrane

88

Plug

100

Connector, transfer device

102

contour

116

Circumferential outer surface

118

longitudinal axis

120

element

122

head Start

124

recess

130

wing

132

wing

136

handle

200

Connector, transfer device

202

tongue

204

tongue

206

catch projection

208

catch projection

210

recess

212

recess

214

outer surface

216

outer surface

218

lower edge

220

lower edge

Claims (14)

1. Transfer device (10, 100, 200) for tapping or delivering a fluid from a bottle (24) sealed with a closure (26, 28) comprising:

   - a hollow cylinder-shaped first part (12) having a circumferential wall (16), which first part can be placed on the bottle and surrounds the closure (26, 28), and a second wall (30) running transverse to the longitudinal axis (80) of the first part (12),

   - a hollow cylindrical second part (14) which can be adjusted in respect of the first part (12), with a first wall (46) running transverse to the longitudinal axis direction,

   - a puncturing needle (48) originating from the first wall (46) and extending in the direction of the first part, permitting piercing of the closure (26, 28), wherein the first part (12) cannot be adjusted axially or largely cannot be adjusted axially with respect to the second part if the closure (26, 28) is not surrounded and the distal end (74) of the puncturing needle (48) runs between the first and the second wall (30, 46), and, if the first part (12) surrounds the closure (26, 28), the first part (12) can be adjusted with respect to the first part (12) for piercing the closure (26, 28),
   characterised in that
   at least one lever element (34, 36) originates from the circumferential wall (16) of the first part (12), with a section (38) extending in the direction of the second part (14), and a second section (40) extending in the direction of the opening of the first part (2) running on the bottle side, wherein, if the first part and second part (12, 14) cannot be adjusted or largely cannot be adjusted in relation to each other, the first section (38) projects laterally outwards over the circumferential wall (16) of the first part (12), and the second section (40) projects into the interior of the first part (12), the first section (38) interacting with the second part in order to prevent the incorrect adjustment of the first part in relation to the second part (14), and, with the first part (12) surrounding the closure (12) of the bottle (24), the second section (40) of the at least one lifting element (34, 36) is adjusted radially outwards, with the simultaneous movement of the first section (38) in and out of engagement with the second part (14), or
   that the second part (14) comprises tongue-shaped elements (202, 204) delimiting slots running in the longitudinal direction (80) of the second part, with projections projecting into the interior of the second part (14), that the projections (206, 208), in the event of the first and second parts (12, 14) not being axially adjustable or largely not adjustable in respect to one another, engage into cut-out apertures (210, 212) running beneath the second wall, which exhibit a distance interval to the lower edge of the first part (12) in such a way that, when the first part surrounds the bottle (24) in locking engagement, the projections, due to interaction with the bottle (24), come out of engagement with the cut-out apertures (210, 212), and, when the puncturing needle (48) penetrates the closure (26), the projections engage behind the lower edge of the first part which runs in the form of a flange.
2. Transfer device in accordance with claim 1,
   characterised in that
   the first part (12) can be adjusted in relation to the second part (14) by axial adjustment or rotation in a telescopic manner.
3. Transfer device in accordance with claim 1 or 2,
   characterised in that
   the second wall (30) is penetrated in the axial extension of the puncturing needle (48).
4. Transfer device in accordance with at least any one of the preceding claims,
   characterised in that
   in the event of the first and second parts not being adjustable or largely not adjustable in respect to one another, the first and second parts (12, 14) are locked in engagement with each other, wherein preferably projections (60) projecting from the inner side of the circumferential wall (44) of the second part (14) engage in cut-out apertures (66, 68) of the circumferential wall (16) of the first part.
5. Transfer device in accordance with at least claim 4,
   characterised in that
   the circumferential wall (16) of the first part (12) comprises depressions, spaced at a distance interval from one another in the axial direction, for the stepped engagement of the projections (60).
6. Transfer device in accordance with at least any one of the preceding claims,
   characterised in that
   the edge of the first part (12) on the opening side comprises projections (20) projecting inwards, for engaging behind an edge (22) surrounding the opening of the bottle (24) in the form of a flange, wherein the moving in and out of engagement between the first section (38) of the at least one lever element (34, 36) and the second part (14) is terminated before the engagement behind the flange-type edge.
7. Transfer device in accordance with at least any one of the preceding claims,
   characterised in that
   by the imposition of pressure on the second wall (30) imposed via the bottle (24), the first part (12) can be adjusted into the second part (14).
8. Transfer device in accordance with at least any one of the preceding claims,
   characterised in that
   from the second wall (30) an element, such as a membrane (60) or plug (88), originates, running in the axial extension of the puncturing needle (48) and providing a seal on the circumference side when the puncturing needle penetrates.
9. Transfer device in accordance with at least any one of the preceding claims,
   characterised in that
   for the rotation of the first part (12) in relation to the second part (14), one of the parts comprises a contour (102) running spirally along its circumferential wall (16, 44) and around the longitudinal axis (118) of the transfer device (100), with which an element (120) interacts, such as a tongue, originating from the other part, in particular from its circumferential wall.
10. Transfer device in accordance with at least claim 9,
    characterised in that
    the contour (102) exhibits a sawtooth profile, and the element (120) exhibits a projection such as a hook, interacting with the contour, wherein an interaction takes place in such a way that a rotation of the first part (12) in relation to the second part (14) takes place exclusively in the penetration direction of the puncturing needle (48).
11. Transfer device in accordance with at least claim 9 or claim 10,
    characterised in that
    the contour (102) projects over the outer circumference surface (116) of the circumferential wall (16) of the first part (12), and that the inner circumferential surface of the first part (12) comprises at least one depression (124), matched at least in sections to the course of the contour, in which the contour is guided.
12. Transfer device in accordance with at least any one of the preceding claims,
    characterised in that
    in order to fix the first part (12) to the bottle (24), a handling element extends from the first part (12), in particular two wings (132, 134) running diametrically to the longitudinal axis (118) and projecting radially from the first part.
13. Transfer device in accordance with at least claim 1,
    characterised in that
    the projections (206, 208) are configured in their free regions in the form of ramps or wedges, in such a way that a surface running obliquely to the longitudinal direction (80) of the transfer device (200) slides along the edge (22) of the bottle (24) running on the connector side.
14. Transfer device in accordance with at least claim 1,
    characterised in that
    the first part (12) locks in engagement with the second part (14) during axial adjustment in such a way that any adjustment against the penetration direction of the puncturing needle (48) is prevented.

Images