EP2822384A1 - Dérivés d'oligosaccharide et de polysaccharide modifiés par une amine de manière bifonctionnelle et multifonctionnelle en tant que substances anti-infectieuses et utilisation desdits dérivés - Google Patents

Dérivés d'oligosaccharide et de polysaccharide modifiés par une amine de manière bifonctionnelle et multifonctionnelle en tant que substances anti-infectieuses et utilisation desdits dérivés

Info

Publication number
EP2822384A1
EP2822384A1 EP13708418.2A EP13708418A EP2822384A1 EP 2822384 A1 EP2822384 A1 EP 2822384A1 EP 13708418 A EP13708418 A EP 13708418A EP 2822384 A1 EP2822384 A1 EP 2822384A1
Authority
EP
European Patent Office
Prior art keywords
polysaccharide
substitution
oligosaccharide
oligo
hydroxyl groups
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP13708418.2A
Other languages
German (de)
English (en)
Inventor
Thomas Heinze
Tim Liebert
Peter Miethe
Kerstin SCHLUFTER
Uta-Christina HIPLER
Cornelia WIEGAND
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Friedrich Schiller Universtaet Jena FSU
Universitaetsklinikum Jena
fzmb Forschungszentrum fur Medizintechnik und Biotechnologie GmbH
Original Assignee
Friedrich Schiller Universtaet Jena FSU
Universitaetsklinikum Jena
fzmb Forschungszentrum fur Medizintechnik und Biotechnologie GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Friedrich Schiller Universtaet Jena FSU, Universitaetsklinikum Jena, fzmb Forschungszentrum fur Medizintechnik und Biotechnologie GmbH filed Critical Friedrich Schiller Universtaet Jena FSU
Priority to EP13708418.2A priority Critical patent/EP2822384A1/fr
Publication of EP2822384A1 publication Critical patent/EP2822384A1/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/64—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with three nitrogen atoms as the only ring hetero atoms
    • A01N43/66—1,3,5-Triazines, not hydrogenated and not substituted at the ring nitrogen atoms
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/34—Shaped forms, e.g. sheets, not provided for in any other sub-group of this main group
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/02—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms
    • A01N43/04—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom
    • A01N43/14—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom six-membered rings
    • A01N43/16—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom six-membered rings with oxygen as the ring hetero atom
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
    • A01N43/54—1,3-Diazines; Hydrogenated 1,3-diazines
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/64—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with three nitrogen atoms as the only ring hetero atoms
    • A01N43/647—Triazoles; Hydrogenated triazoles
    • A01N43/653—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Dentistry (AREA)
  • Plant Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Agronomy & Crop Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Toxicology (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

L'invention concerne l'utilisation d'un oligosachharide ou polysaccharide construit à partir d'une unité de base (degré de polymérisation (DP) - valeurs supérieures à 10) comprenant des groupes hydroxyle qui portent au moins en partie des substituants qui possèdent des fonctions di-, tri- ou tétra-amines sans charge permanente, comme moyens antibactériens et antimycosiques. L'oligosaccharide ou le polysaccharide construit à partir d'une unité de base peut être obtenu par formation de dérivés des groupes hydroxyle d'un oligosaccharide ou polysaccharide pour obtenir des groupes partants, ce qui permet d'obtenir un oligosaccharide ou polysaccharide transformé en dérivé, suivi d'une transformation de l'oligosaccharide ou du polysaccharide transformé en dérivé avec une amine, qui présente au moins deux fonctions amine capables d'obtenir une substitution nucléophile, en mettant en œuvre une substitution nucléophile pour obtenir l'oligosaccharide ou le polysaccharide aminosubstitué. Les groupes hydroxyle de l'oligosaccharide ou du polysaccharide sont substitués au moins en partie par l'amine, qui comprend au moins deux fonctions amine capables d'obtenir une substitution nucléophile, par un degré de substitution moyen, qui présente une valeur >. 0,1. Le degré de substitution moyen est défini comme le quotient du nombre d'amines présentant au moins deux fonctions amine accessibles à une substitution nucléophile, qui ont été introduites par la substitution dans l'oligosaccharide ou le polysaccharide, divisé par le nombre de groupes hydroxyle d'origine de l'oligosaccharide ou du polysaccharide, multiplié par le nombre de groupes hydroxyle d'origine par unité de base oligo et polymère.
EP13708418.2A 2012-03-09 2013-03-08 Dérivés d'oligosaccharide et de polysaccharide modifiés par une amine de manière bifonctionnelle et multifonctionnelle en tant que substances anti-infectieuses et utilisation desdits dérivés Withdrawn EP2822384A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP13708418.2A EP2822384A1 (fr) 2012-03-09 2013-03-08 Dérivés d'oligosaccharide et de polysaccharide modifiés par une amine de manière bifonctionnelle et multifonctionnelle en tant que substances anti-infectieuses et utilisation desdits dérivés

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP12158792 2012-03-09
EP13708418.2A EP2822384A1 (fr) 2012-03-09 2013-03-08 Dérivés d'oligosaccharide et de polysaccharide modifiés par une amine de manière bifonctionnelle et multifonctionnelle en tant que substances anti-infectieuses et utilisation desdits dérivés
PCT/EP2013/054719 WO2013132061A1 (fr) 2012-03-09 2013-03-08 Dérivés d'oligosaccharide et de polysaccharide modifiés par une amine de manière bifonctionnelle et multifonctionnelle en tant que substances anti-infectieuses et utilisation desdits dérivés

Publications (1)

Publication Number Publication Date
EP2822384A1 true EP2822384A1 (fr) 2015-01-14

Family

ID=47844319

Family Applications (1)

Application Number Title Priority Date Filing Date
EP13708418.2A Withdrawn EP2822384A1 (fr) 2012-03-09 2013-03-08 Dérivés d'oligosaccharide et de polysaccharide modifiés par une amine de manière bifonctionnelle et multifonctionnelle en tant que substances anti-infectieuses et utilisation desdits dérivés

Country Status (3)

Country Link
EP (1) EP2822384A1 (fr)
IN (1) IN2014DN07422A (fr)
WO (1) WO2013132061A1 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3227379B1 (fr) * 2014-12-02 2020-07-29 B.G. Negev Technologies and Applications Ltd., at Ben-Gurion University Amidons quaternisés destinés à être utilisés en tant qu'agents antimicrobiens
CN108530546B (zh) * 2018-04-20 2020-06-09 厦门大学 拟壳聚糖及其衍生物的合成及应用
CN110551226B (zh) * 2019-07-30 2021-06-08 大连理工大学 一种亲/疏水性可控转换的叔胺型含氮聚糖衍生物及其制备方法和应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6116901A (ja) 1984-07-03 1986-01-24 Daicel Chem Ind Ltd カルボキシメチルセルロ−スの第四アンモニウム塩及びその製造法
US5981737A (en) 1997-03-21 1999-11-09 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Cationic cellulose derivatives of controlled charge density useful in cosmetic preparations
DE10200717A1 (de) 2002-01-10 2003-07-31 Knoell Hans Forschung Ev Verwendung von Polysaccharid-Derivaten als antiinfektive Substanzen
DE102004014483A1 (de) 2004-03-24 2005-10-13 Gesellschaft zur Förderung von Medizin-, Bio- und Umwelttechnologien e.V. Antimikrobielle Beschichtungszusammensetzung und Verfahren zu deren Herstellung
DE102004047115B9 (de) 2004-09-27 2007-10-31 Universität Hamburg Verfahren zur Herstellung einer Wundauflage
DE102005008434A1 (de) 2005-02-24 2006-09-07 Forschungszentrum Jülich GmbH Verfahren zur Modifizierung eines Substrats
WO2006092057A1 (fr) 2005-03-04 2006-09-08 Laboratoires Mauves Inc. Polymères à base d’amines et à base d’imines, leurs utilisations et leur préparation
WO2007028012A2 (fr) 2005-09-01 2007-03-08 Isis Pharmaceuticals, Inc. Analogues d'aminoglycosides 4,5-substitues 6'-modifies antibacteriens
FI20065350L (fi) 2006-05-24 2007-11-25 Scitech Service Oy Ltd Antimikrobinen polymeerimateriaali ja sen käyttö
CA2608824A1 (fr) 2006-10-31 2008-04-30 University Of New Brunswick Polymeres antimicrobiens et modifies avec un agent bacteriostatique pour des fibres de cellulose

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
None *
See also references of WO2013132061A1 *

Also Published As

Publication number Publication date
IN2014DN07422A (fr) 2015-04-24
WO2013132061A1 (fr) 2013-09-12

Similar Documents

Publication Publication Date Title
Kurniasih et al. Carboxymethyl chitosan as an antifungal agent on gauze
Kohsari et al. Antibacterial electrospun chitosan–polyethylene oxide nanocomposite mats containing bioactive silver nanoparticles
Lee et al. Electrospun chitosan nanofibers with controlled levels of silver nanoparticles. Preparation, characterization and antibacterial activity
Demircan et al. Facile synthesis of novel soluble cellulose-grafted hyperbranched polymers as potential natural antimicrobial materials
Amirabad et al. Improved antifungal activity and stability of chitosan nanofibers using cellulose nanocrystal on banknote papers
Song et al. Preparation and characterization of arginine-modified chitosan/hydroxypropyl methylcellose antibacterial film
Amor et al. Biosynthesis MgO and ZnO nanoparticles using chitosan extracted from Pimelia Payraudi Latreille for antibacterial applications
Huang et al. Synthesis of sulfonated chitosan and its antibiofilm formation activity against E. coli and S. aureus
Zhou et al. Engineering a novel antibacterial agent with multifunction: Protocatechuic acid-grafted-quaternized chitosan
Másson Antimicrobial properties of chitosan and its derivatives
Salama et al. Preparation of biocompatible chitosan nanoparticles loaded with Aloe vera extract for use as a novel drug delivery mechanism to improve the antibacterial characteristics of cellulose-based fabrics
Sun et al. Facile synthesis and light-induced antibacterial activity of ketoprofen functionalized bacterial cellulose membranes
Bandatang et al. Antimicrobial electrospun nanofiber mats of NaOH-hydrolyzed chitosan (HCS)/PVP/PVA incorporated with in-situ synthesized AgNPs: Fabrication, characterization, and antibacterial activity
Tejero et al. Copolymers of acrylonitrile with quaternizable thiazole and triazole side-chain methacrylates as potent antimicrobial and hemocompatible systems
Ding et al. Alpha-terpineol grafted acetylated lentinan as an anti-bacterial adhesion agent
Bansal et al. Functionalization of nanocellulose to quaternized nanocellulose tri-iodide and its evaluation as an antimicrobial agent
Huang et al. Functional modification of polydimethylsiloxane nanocomposite with silver nanoparticles-based montmorillonite for antibacterial applications
EP2822384A1 (fr) Dérivés d'oligosaccharide et de polysaccharide modifiés par une amine de manière bifonctionnelle et multifonctionnelle en tant que substances anti-infectieuses et utilisation desdits dérivés
Wang et al. Engineering antimicrobial and biocompatible electrospun PLGA fibrous membranes by irradiation grafting polyvinylpyrrolidone and periodate
Bayoumi et al. The behavior of natural biomass materials as drug carriers in releasing loaded Gentamicin sulphate
Meher et al. Bifunctional Dalteparin/Enoxaparin coated nanosilver formulation to prevent bloodstream infections during hemodialysis
Song et al. Long term antibacterial effect cellulose film was modified with polyhexamethylene biguanide (PHMB)
Saini et al. Natural active molecule chemical grafting on the surface of microfibrillated cellulose for fabrication of contact active antimicrobial surfaces
Wu et al. Chitosan-based nanopesticides enhanced anti-fungal activity against strawberry anthracnose as “sugar-coated bombs”
Chen et al. Antibacterial gauze based on the synergistic antibacterial mechanism of antimicrobial peptides and silver nanoparticles

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20140918

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

AX Request for extension of the european patent

Extension state: BA ME

DAX Request for extension of the european patent (deleted)
17Q First examination report despatched

Effective date: 20171027

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20190822