EP2785874A4 - Personalized pain management and anesthesia: preemptive risk identification and therapeutic decision support - Google Patents
Personalized pain management and anesthesia: preemptive risk identification and therapeutic decision supportInfo
- Publication number
- EP2785874A4 EP2785874A4 EP12854522.5A EP12854522A EP2785874A4 EP 2785874 A4 EP2785874 A4 EP 2785874A4 EP 12854522 A EP12854522 A EP 12854522A EP 2785874 A4 EP2785874 A4 EP 2785874A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- anesthesia
- decision support
- risk identification
- pain management
- therapeutic decision
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 206010002091 Anaesthesia Diseases 0.000 title 1
- 230000037005 anaesthesia Effects 0.000 title 1
- 230000036407 pain Effects 0.000 title 1
- 230000001225 therapeutic effect Effects 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/172—Haplotypes
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP18196397.6A EP3483288B1 (en) | 2011-11-30 | 2012-11-29 | Personalized pain management and anesthesia: preemptive risk identification |
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201161565400P | 2011-11-30 | 2011-11-30 | |
US201261661073P | 2012-06-18 | 2012-06-18 | |
PCT/US2012/067111 WO2013082308A1 (en) | 2011-11-30 | 2012-11-29 | Personalized pain management and anesthesia: preemptive risk identification and therapeutic decision support |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP18196397.6A Division EP3483288B1 (en) | 2011-11-30 | 2012-11-29 | Personalized pain management and anesthesia: preemptive risk identification |
Publications (3)
Publication Number | Publication Date |
---|---|
EP2785874A1 EP2785874A1 (en) | 2014-10-08 |
EP2785874A4 true EP2785874A4 (en) | 2015-08-19 |
EP2785874B1 EP2785874B1 (en) | 2018-09-26 |
Family
ID=48536065
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP18196397.6A Active EP3483288B1 (en) | 2011-11-30 | 2012-11-29 | Personalized pain management and anesthesia: preemptive risk identification |
EP12854522.5A Not-in-force EP2785874B1 (en) | 2011-11-30 | 2012-11-29 | Personalized pain management and anesthesia: preemptive risk identification and therapeutic decision support |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP18196397.6A Active EP3483288B1 (en) | 2011-11-30 | 2012-11-29 | Personalized pain management and anesthesia: preemptive risk identification |
Country Status (3)
Country | Link |
---|---|
US (5) | US9944985B2 (en) |
EP (2) | EP3483288B1 (en) |
WO (1) | WO2013082308A1 (en) |
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US8930178B2 (en) | 2007-01-04 | 2015-01-06 | Children's Hospital Medical Center | Processing text with domain-specific spreading activation methods |
EP3483288B1 (en) | 2011-11-30 | 2022-03-16 | Children's Hospital Medical Center | Personalized pain management and anesthesia: preemptive risk identification |
US20140274763A1 (en) * | 2013-03-15 | 2014-09-18 | Pathway Genomics Corporation | Method and system to predict response to pain treatments |
JP6539274B2 (en) | 2013-08-12 | 2019-07-03 | ファーマシューティカル マニュファクチュアリング リサーチ サービシズ,インコーポレーテッド | Extruded immediate release abuse deterrent pills |
WO2015095391A1 (en) | 2013-12-17 | 2015-06-25 | Pharmaceutical Manufacturing Research Services, Inc. | Extruded extended release abuse deterrent pill |
US9492444B2 (en) | 2013-12-17 | 2016-11-15 | Pharmaceutical Manufacturing Research Services, Inc. | Extruded extended release abuse deterrent pill |
CA2940422A1 (en) * | 2014-02-24 | 2015-08-27 | Children's Hospital Medical Center | Methods and compositions for personalized pain management |
CN104144420B (en) * | 2014-02-26 | 2015-11-25 | 腾讯科技(深圳)有限公司 | A kind of radio switch-in method and relevant device, system |
JP6371463B2 (en) | 2014-07-17 | 2018-08-08 | ファーマシューティカル マニュファクチュアリング リサーチ サービシズ,インコーポレーテッド | Immediate release abuse deterrent liquid filler form |
EP3177738B1 (en) | 2014-08-08 | 2019-10-09 | Children's Hospital Medical Center | Diagnostic method for distinguishing forms of esophageal eosinophilia |
EP2987451A1 (en) | 2014-08-18 | 2016-02-24 | Tools 4 Patient sa | Method and tools for predicting a pain response in a subject |
AU2015336065A1 (en) | 2014-10-20 | 2017-05-04 | Pharmaceutical Manufacturing Research Services, Inc. | Extended release abuse deterrent liquid fill dosage form |
WO2016176475A2 (en) * | 2015-04-28 | 2016-11-03 | Proove Biosciences, Inc. | System and method for processing genotype information relating to opioid response |
US20180322960A1 (en) * | 2015-04-28 | 2018-11-08 | Proove Biosciences, Inc. | System and method for processing genotype information relating to nsaid risk |
WO2017059022A1 (en) * | 2015-09-30 | 2017-04-06 | Inform Genomics, Inc. | Systems and methods for predicting treatment-regiment-related outcomes |
TWI626617B (en) * | 2015-12-11 | 2018-06-11 | 義守大學 | Method for estimating anesthesia risk |
EP3402572B1 (en) | 2016-01-13 | 2022-03-16 | Children's Hospital Medical Center | Compositions and methods for treating allergic inflammatory conditions |
EP3571309A4 (en) | 2017-01-20 | 2020-11-25 | Children's Hospital Medical Center | Methods and compositions relating to oprm1 dna methylation for personalized pain management |
US10426400B2 (en) | 2017-06-23 | 2019-10-01 | International Business Machines Corporation | Optimized individual sleep patterns |
US11011264B2 (en) | 2017-08-09 | 2021-05-18 | Varian Medical Systems International Ag | Radiotherapy treatment planning using artificial intelligence (AI) engines |
US11859250B1 (en) | 2018-02-23 | 2024-01-02 | Children's Hospital Medical Center | Methods for treating eosinophilic esophagitis |
EP3813814A4 (en) * | 2018-06-28 | 2022-06-29 | Children's Hospital Medical Center | Methods and compositions relating to personalized pain management |
WO2020172432A1 (en) * | 2019-02-21 | 2020-08-27 | Children's Hospital Medical Center | Methods and compositions for the detection, classification, and diagnosis of chronic post-surgical pain |
US20200329698A1 (en) * | 2019-04-19 | 2020-10-22 | Nobilis Therapeutics, Inc. | Compositions for organ graft preservation and methods of use |
CN111455038B (en) * | 2020-04-07 | 2021-03-05 | 上海康黎医学检验所有限公司 | Kit for guiding drug for anxiety disorder of human and application thereof |
WO2021211575A1 (en) * | 2020-04-13 | 2021-10-21 | The Regents Of The Univefisity Of California | Compositions comprising propofol, ketamine, and non-opioid analgesic, and methods of use |
CN112980946B (en) * | 2021-04-28 | 2022-08-26 | 华中科技大学同济医学院附属协和医院 | Gene polymorphism detection kit and detection method for guiding administration of rocuronium bromide serving as skeletal muscle relaxant |
WO2023102425A1 (en) * | 2021-11-30 | 2023-06-08 | East Carolina University | Methods for determining opioid responsiveness in the treatment of pain |
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WO2009067473A2 (en) * | 2007-11-20 | 2009-05-28 | Wisconsin Alumni Research Foundation | Method of improving palliative care |
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EP3177738B1 (en) | 2014-08-08 | 2019-10-09 | Children's Hospital Medical Center | Diagnostic method for distinguishing forms of esophageal eosinophilia |
EP3571309A4 (en) | 2017-01-20 | 2020-11-25 | Children's Hospital Medical Center | Methods and compositions relating to oprm1 dna methylation for personalized pain management |
EP3813814A4 (en) | 2018-06-28 | 2022-06-29 | Children's Hospital Medical Center | Methods and compositions relating to personalized pain management |
-
2012
- 2012-11-29 EP EP18196397.6A patent/EP3483288B1/en active Active
- 2012-11-29 WO PCT/US2012/067111 patent/WO2013082308A1/en active Application Filing
- 2012-11-29 EP EP12854522.5A patent/EP2785874B1/en not_active Not-in-force
- 2012-11-29 US US14/361,946 patent/US9944985B2/en active Active
-
2018
- 2018-03-08 US US15/915,581 patent/US10662476B2/en active Active
-
2020
- 2020-04-16 US US16/850,537 patent/US11597978B2/en active Active
- 2020-06-19 US US16/946,399 patent/US20200318194A1/en active Pending
- 2020-06-19 US US16/946,401 patent/US11746377B2/en active Active
Patent Citations (1)
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WO2009067473A2 (en) * | 2007-11-20 | 2009-05-28 | Wisconsin Alumni Research Foundation | Method of improving palliative care |
Non-Patent Citations (8)
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COULBAULT ET AL: "Environmental and genetic factors associated with morphine response in the postoperative period", CLINICAL PHARMACOLOGY AND THERAPEUTICS, NATURE PUBLISHING GROUP, US, vol. 79, no. 4, 1 April 2006 (2006-04-01), pages 316 - 324, XP005406427, ISSN: 0009-9236, DOI: 10.1016/J.CLPT.2006.01.007 * |
DE GREGORI M ET AL: "Individualizing pain therapy with opioids: The rational approach based on pharmacogenetics and pharmacokinetics", EUROPEAN JOURNAL OF PAIN SUPPLEMENTS, ELSEVIER, AMSTERDAM, NL, vol. 4, no. 4, 1 November 2010 (2010-11-01), pages 245 - 250, XP027461235, ISSN: 1754-3207, [retrieved on 20101101], DOI: 10.1016/J.EUJPS.2010.09.011 * |
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KLEINE-BRUEGGENEY M ET AL: "Pharmacogenetics in palliative care", FORENSIC SCIENCE INTERNATIONAL, ELSEVIER SCIENTIFIC PUBLISHERS IRELAND LTD, IE, vol. 203, no. 1-3, 15 December 2010 (2010-12-15), pages 63 - 70, XP027514419, ISSN: 0379-0738, [retrieved on 20100814], DOI: 10.1016/J.FORSCIINT.2010.07.003 * |
ROSS JOY R ET AL: "Genetic variation and response to morphine in cancer patients - Catechol-O-methyltransferase and multidrug resistance-1 gene polymorphisms are associated with central side effects", CANCER, vol. 112, no. 6, March 2008 (2008-03-01), pages 1390 - 1403, XP009185223, ISSN: 0008-543X * |
SADHASIVAM S ET AL: "Pharmacogenetics and personalizing perioperative analgesia in children", JOURNAL OF PAIN, SAUNDERS, PHILADELPHIA, PA, US, vol. 11, no. 4, 1 April 2010 (2010-04-01), pages S50, XP027094770, ISSN: 1526-5900, [retrieved on 20100401] * |
ZWISLER STINE T ET AL: "The antinociceptive effect and adverse drug reactions of oxycodone in human experimental pain in relation to genetic variations in the OPRM1 and ABCB1 genes", FUNDAMENTAL & CLINICAL PHARMACOLOGY, vol. 24, no. 4, August 2010 (2010-08-01), pages 517 - 524, XP002741938, ISSN: 0767-3981 * |
Also Published As
Publication number | Publication date |
---|---|
US20200308648A1 (en) | 2020-10-01 |
EP3483288B1 (en) | 2022-03-16 |
WO2013082308A1 (en) | 2013-06-06 |
US10662476B2 (en) | 2020-05-26 |
US20140371256A1 (en) | 2014-12-18 |
EP3483288A3 (en) | 2019-06-05 |
US11746377B2 (en) | 2023-09-05 |
US20200318194A1 (en) | 2020-10-08 |
EP2785874A1 (en) | 2014-10-08 |
EP3483288A2 (en) | 2019-05-15 |
US11597978B2 (en) | 2023-03-07 |
US20200340061A1 (en) | 2020-10-29 |
EP2785874B1 (en) | 2018-09-26 |
US20180334717A1 (en) | 2018-11-22 |
US9944985B2 (en) | 2018-04-17 |
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RIN1 | Information on inventor provided before grant (corrected) |
Inventor name: MCAULIFFE, JOHN Inventor name: PROWS, CYNTHIA A. Inventor name: SADHASIVAM, SENTHILKUMAR Inventor name: FUKUDA, TSUYOSHI Inventor name: ZHANG, KEJIAN Inventor name: MELLER, JAROLSAW Inventor name: CHILDAMBARAN, VIDYA |
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