EP2759789A1 - Appareil pour manipuler des contenants de médicament - Google Patents

Appareil pour manipuler des contenants de médicament Download PDF

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Publication number
EP2759789A1
EP2759789A1 EP13305089.8A EP13305089A EP2759789A1 EP 2759789 A1 EP2759789 A1 EP 2759789A1 EP 13305089 A EP13305089 A EP 13305089A EP 2759789 A1 EP2759789 A1 EP 2759789A1
Authority
EP
European Patent Office
Prior art keywords
plane area
cold storage
working
enclosure
compartment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP13305089.8A
Other languages
German (de)
English (en)
Inventor
Wan Leng Lim
Kenneth Loh
Franck Carrel
Patrick LE GAL-REDON
Alexandre Souillard
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Becton Dickinson France SA
Original Assignee
Becton Dickinson France SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Becton Dickinson France SA filed Critical Becton Dickinson France SA
Priority to EP13305089.8A priority Critical patent/EP2759789A1/fr
Publication of EP2759789A1 publication Critical patent/EP2759789A1/fr
Withdrawn legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/16—Holders for containers
    • A61J1/165—Cooled holders, e.g. for medications, insulin, blood, plasma
    • A—HUMAN NECESSITIES
    • A45—HAND OR TRAVELLING ARTICLES
    • A45C—PURSES; LUGGAGE; HAND CARRIED BAGS
    • A45C11/00—Receptacles for purposes not provided for in groups A45C1/00-A45C9/00
    • A—HUMAN NECESSITIES
    • A45—HAND OR TRAVELLING ARTICLES
    • A45C—PURSES; LUGGAGE; HAND CARRIED BAGS
    • A45C11/00—Receptacles for purposes not provided for in groups A45C1/00-A45C9/00
    • A45C11/20—Lunch or picnic boxes or the like
    • A—HUMAN NECESSITIES
    • A45—HAND OR TRAVELLING ARTICLES
    • A45C—PURSES; LUGGAGE; HAND CARRIED BAGS
    • A45C13/00—Details; Accessories
    • A45C13/34—Stays or supports for holding lids or covers open
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
    • F25D—REFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
    • F25D3/00—Devices using other cold materials; Devices using cold-storage bodies
    • F25D3/02—Devices using other cold materials; Devices using cold-storage bodies using ice, e.g. ice-boxes
    • F25D3/06—Movable containers
    • F25D3/08—Movable containers portable, i.e. adapted to be carried personally
    • A—HUMAN NECESSITIES
    • A45—HAND OR TRAVELLING ARTICLES
    • A45C—PURSES; LUGGAGE; HAND CARRIED BAGS
    • A45C11/00—Receptacles for purposes not provided for in groups A45C1/00-A45C9/00
    • A45C2011/007—Receptacles for personal medical or care products, e.g. drugs, condoms or patches; Small first-aid kits
    • A—HUMAN NECESSITIES
    • A45—HAND OR TRAVELLING ARTICLES
    • A45C—PURSES; LUGGAGE; HAND CARRIED BAGS
    • A45C13/00—Details; Accessories
    • A45C13/02—Interior fittings; Means, e.g. inserts, for holding and packing articles
    • A45C2013/026—Inserts
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
    • F25D—REFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
    • F25D2303/00—Details of devices using other cold materials; Details of devices using cold-storage bodies
    • F25D2303/08—Devices using cold storage material, i.e. ice or other freezable liquid
    • F25D2303/082—Devices using cold storage material, i.e. ice or other freezable liquid disposed in a cold storage element not forming part of a container for products to be cooled, e.g. ice pack or gel accumulator
    • F25D2303/0822—Details of the element
    • F25D2303/08221—Fasteners or fixing means for the element
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
    • F25D—REFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
    • F25D2303/00—Details of devices using other cold materials; Details of devices using cold-storage bodies
    • F25D2303/08—Devices using cold storage material, i.e. ice or other freezable liquid
    • F25D2303/084—Position of the cold storage material in relationship to a product to be cooled
    • F25D2303/0843—Position of the cold storage material in relationship to a product to be cooled on the side of the product
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
    • F25D—REFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
    • F25D2303/00—Details of devices using other cold materials; Details of devices using cold-storage bodies
    • F25D2303/08—Devices using cold storage material, i.e. ice or other freezable liquid
    • F25D2303/084—Position of the cold storage material in relationship to a product to be cooled
    • F25D2303/0844—Position of the cold storage material in relationship to a product to be cooled above the product

Definitions

  • the present invention relates to an apparatus for the transportation of, and operations on, drug containers, the containers being intended to be used in combination with drug administering devices, such as syringes.
  • vaccines are complex to handle and to store. Many vaccine compositions are usually not stable at room temperatures and they must be stored at rather specific cold temperatures. Indeed, vaccines are usually temperature sensitive and typically need to be maintained and stored at any time between 2 and 8 degrees Celsius (°C). Some vaccines will be more sensitive to heat exposure and others will be sensitive to freezing. Therefore, maintaining and monitoring the appropriate temperatures during the storage and the handling of vaccines is a critical issue in order to sustain their efficacy. Overexposure to heat as well as overcooling may result in the destruction of the biological elements of the vaccines.
  • the cold chain be not interrupted from production of the drug at a pharmaceutical company to its administration to the patient.
  • the most efficient vaccine packaging is the multidose container, that is to say, containers that may contain up to 10, 100 or 1000 doses of vaccine, one dose being intended for one patient. Nevertheless, it may happen that a multidose container, such as for example a 10-dose container, is opened and that only three doses are used, for vaccinating three patients only, the rest of the container being wasted because of repeated exposure at temperature above 8°C. Indeed, when a vaccine has been submitted several times to ambiant temperature, it is considered that it has been damaged and should not be further injected.
  • the multidose vials may be handled and manipulated outdoors, at ambiant air.
  • Vaccination campaigns can therefore be made difficult in regions where there is limited or potentially no supply of energy to power cooling equipment such as a refrigerator. As a result, a significant proportion of vaccines may be wasted by the time they reach their target. This has an unacceptable cost for the health organizations in charge of immunization campaigns. In addition, it may happen that in case of vaccination campaigns, or pandemic, hundreds of patients need to be vaccinated in a very short time, in locations where it is difficult to maintain good hygienic conditions such as locations which are far from towns and from hospital facilities.
  • Apparatus for transporting drug containers provided with refrigeration systems, have been proposed.
  • the drug container may be exposed to temperature above 8°C, thereby leading to the wastage of vaccine doses.
  • it would be desirable that such an apparatus allows performing these operations without having to implement sophisticated technology and energy consumming techniques.
  • the apparatus of the invention allows the transportation of prefilled drug containers in good temperature conditions, as the working cold storage accumulator located in the enclosure enables the maintenance of the temperature in the first compartment, also located in the enclosure, at a predetermined temperature range, for example 2-8 °C.
  • the apparatus of the invention allows the removal of the working cold storage accumulator from the enclosure and the securing of such a working cold storage accumulator on a plane area capable of being located outside the enclosure, for example capable of facing ambiant air, allowing then the healthcare worker to set up a convenient working space where he may position a selected drug container next to the working cold storage accumulator snap-fitted to the plane area.
  • the healthcare worker may substantially align the plane area of the apparatus of the invention on a horizontal area, such as the ground or a table, and the plane area of the apparatus of the inevntion may receive a drug container in an upright position in a stable manner.
  • the plane area of the apparatus of the invention may constitute an aseptic plane working space for the healthcare worker.
  • the plane area is capable of adopting a working configuration in which it is located outside the enclosure.
  • the plane area faces the outside environment, and in particular enough space in the outside environment, such as ambiant air, for receiving the working cold accumulator within its snap-fitting means.
  • Outside the enclosure means, according to the present application, separate from the inside of the enclosure or located on a surface of the enclosure capable of facing the outside environment, such as an outer face of the enclosure or a movable wall of the enclosure capable of facing the outside environment at some point.
  • the plane area may be located on an element positioned inside the enclosure, said element being removable from the enclosure when the plane area needs to be in its working configuration. In other embodiments, the plane area may be located on the outer surface of the enclosure.
  • the plane area may be designed on the outer face of a wall of the enclosure of the apparatus of the invention.
  • the plane area may be designed on an outer face of one of the large sides of the case, the opening of the case being located on a small side of the case.
  • the plane area which is designed on the opposite large side, faces the outside environment, such as the ambiant air, and in addition is substantially aligned with a horizontal plane.
  • the plane area is in its working configuration.
  • the healthcare worker then snap-fits the working cold storage accumulator onto the plane area and positions the selected drug container on the plane area, next to the working cold storage accumulator.
  • the healthcare worker may then proceed to the withdrawal of the doses of product/vaccine contained in the drug container without having to fear that the temperature of the container raises dramatically in a short time.
  • said plane area is linked to said apparatus so that said plane area is capable of being switched from its working configuration to a storage configuration, in which said plane area is protected from the ouside environment.
  • the plane area is in a relationship with the apparatus allowing the plane area to switch from a storage configuration, in which it is protected from the ouside environment such as ambiant air, to its working configuration, in which it faces the outside environement, in particular in which it is surrounded by enough space in the outside environment so that the working cold storage accumulator may be snap-fitted on said plane area.
  • the plane area in particular when it is designed on an outer wall of the enclosure, may be provided with a shutter protecting it from the ouside environment, and in particular from ambiant air, when no operation is performed on a drug container and the apparatus is for example in a storage mode, the shutter being capable of pivoting or sliding with respect to the plane area so as to leave said plane area exposed to the outside environment and ambiant air when needed.
  • the healthcare worker moves the shutter so that the plane area faces the outside environment and is therefore capable of receiving the working cold storage accumulator.
  • the plane area may be designed on a face of a pivoting or sliding shutter provided on the outer wall of the enclosure, so that, when the shutter is shut, the plane area faces the enclosure wall and is therefore protected from the outside environment, and when the shutter is open, the plane area faces the outside environment and is capable of receiving the working cold storage accumulator.
  • said plane area is designed on a face of a plate member releasingly connected to the enclosure.
  • the plate member may then be an independent element having a substantially bidimensional shape capable of being stored inside the enclosure when no operation is to be perfomed on a drug container, and then removed from the inside of the enclosure in order to put the plane area in its working configuration.
  • the plate member may be put on the ground or on any horizontal area.
  • the plate member may be stored inside the enclosure independently from the working cold storage accumulator. In such a case, the working cold storage accumulator may be removed from the second compartment and then snap-fitted onto the plane area designed on a face of the plate member, with the opposite face of the plate member having been previously put on the ground.
  • the plate member may be stored inside the second compartment, with the working cold storage accumulator already snap-fitted onto the plane area designed on said plate member.
  • the plate member and the working cold storage accumulator already snap-fitted thereon are removed simultaneously from the second compartment and the face of the plate member not bearing the working cold storage accumulator is for example preferably put on a horizontal area.
  • the plate member forms at least part of a cover for closing said closable opening.
  • the plane area is designed on a face of the cover.
  • said cover having an inner face intended to be directed towards the inside of the enclosure when said cover closes said closable opening, said plane area is designed on said inner face of said cover.
  • the plane area is therefore protected from the outside environment when no operation is to be performed on a drug container, for example during the storage mode of the apparatus.
  • the inner face of the cover being for example intended to face the outside environment when the cover does not close the closable opening, the plane area is then in its working configuration.
  • the working cold storage accumulator is provided with at least one lodging capable of receiving at least one of said drug containers.
  • said lodging(s) may receive one or more drug containers, when said working cold storage accumulator is snap-fitted onto the plane area in its working configuration.
  • Such embodiments are particularly useful for drugs or vaccines which can sustain very low temperature, namely below 2 °C. As the drug container is lodged within the working cold storage accumulator, the temperature of the drug container is maintained at a desired range for a longer time.
  • the plane area is further provided with releasable fixing means for temporarily securing one or more of said drug container(s) onto said plane area.
  • the drug container to be treated may also be releasably fixed onto the plane area, when the plane area is in its working configuration. The working space is therefore safer, as the drug containers are secured and may not fall or roll away from the plane area. The procedure of withdrawing a dose of product from the drug container is therefore rendered easier and safer for the healthcare worker.
  • said releasable fixing means are located adjacent to said snap-fitting means.
  • Such embodiments may be useful for vaccines which may not sustain very low temperature.
  • the working cold storage accumulator and one or more container(s) are both secured on said plane area. The proximity with the working cold storage acumulator may then protect the drug containers from excessive heating during a significant period of time, in particular, during the time required for a healthcare worker to withdraw the doses of product and prepare the injections, without risking that the vaccine be overcooled by very low temperature. Potential waste of the vaccine is therefore avoided.
  • the enclosure further comprises at least a third compartment for storing additional cold storage accumulators.
  • additional cold storage accumulators may contribute to the maintenance of the desired temperature range inside the enclosure at any time, during storage and working modes of the apparatus.
  • the additional cold storage accumulators may maintain the desired temperature range inside the enclosure, even after the working cold storage accumulator has been removed from the second compartment, and during the time it is is snap-fitted onto the plane area for operation on a selected drug container. The drug containers which remain inside the enclosure are therefore maintained at a controlled temperature.
  • the second compartment is insulated independently from said first, and optionally third, compartment(s).
  • the various compartments of the enclosure are preferably insulated from the ambiant air and from the ambiant temperature.
  • the second compartment may be insulated independently from said first and optionally third compartment(s).
  • the enclosure is further provided with a holding strap.
  • the apparatus is therefore easily transportable for a healthcare worker, even in remote locations accessible only by foot.
  • the plate member is slidingly connected to the holding strap.
  • the cover may be slidingly connected to the strap.
  • the plane area may therefore be secured to the apparatus and cannot be lost in remote locations.
  • Another aspect of the invention is a method for proceeding to the withdrawal of dose(s) of product from drug containers stored in an apparatus as above described, comprising the following steps :
  • an apparatus 1 for transporting and performing operations on a plurality of drug containers 100 filled with a drug solution.
  • the drug solution may be a product that needs to be maintained at a determined temperature range, such as a vaccine.
  • a vaccine for example, some vaccines need to be maintained at a temperature range varying from 2 to 8°C.
  • the apparatus 1 is shown in a storage mode, namely in a mode where no operation is completed on the drug containers 100.
  • the storage mode of the apparatus 1 is useful for storing and transporting the drug containers 100 at a predetermined temperature range, for example for carrying such drug containers 100 to a remote location where electrical power is absent or scarce but where people need to be vaccinated.
  • the apparatus 1 comprises an enclosure under the form of a case 2 having a substantially rectangular shape in the example shown, provided with a top opening 3 closable by a removable cover 4 having a outer face 4a and an inner face 4b, opposite its outer face 4a.
  • the walls of the case 2 can be suitably made of an insulating material such as, for example, a sandwich of different layers having a hard and smooth surface on the outside for durability and hygiene, as well as internal layer(s) of for example polystyrene foam for thermal insulation purposes.
  • the case 2 comprises a first compartment 5 for storing the plurality of drug containers 100, and a second compartment 6 for storing a working cold storage accumulator 7 on the example shown.
  • the working cold storage accumulator 7 is intended to be removed from the second compartment 6 when the apparatus 1 is in a working mode, namely in a mode where various operations, such as withdrawal of doses of product or vaccine, are to be performed on some selected drug containers (100), which also need to be removed from the enclosure for purposes of performing said operations.
  • the working cold storage accumulator 7 has the shape of a rectangular pack on the example shown, and is provided with a first lodging 7a and a second lodging 7b, both of them being shaped and dimensioned to receive a drug container 100.
  • the first lodging 7a and the second lodging 7b do not have the same diameter so that drug containers 100 of various sizes and shapes may be received therein.
  • the lodgings (7a, 7b) could have the same shape and dimensions.
  • the working cold storage accumulator 7 could be provided with only one of such lodgings (7a, 7b) or on the contrary with more than two lodgings.
  • the apparatus 1 comprises only one such removable working cold storage accumulator 7.
  • several such removal working cold storage accumulators may be present.
  • the case 2 further comprises a third compartment 8 for storing additional cold storage accumulators 9 (see also Figure 10 ).
  • additional cold storage accumulators 9 are removable from the third compartment 8 in order to regenerate their cooling power when needed, they are not intended to be removed from the case 2 when the apparatus 1 is in a working mode and operations are to be perdormed on selected drug containers.
  • the additional cold storage accumulators 9 are intended to protect the inside of the case 2, and in particular the first compartment 5 and the drug containers 100 stored therein, from excessive heat from the outside environment and to maintain a controlled temperature inside the case 2.
  • the third compartment 8 is U-shaped (see Figure 10 ) and receives three additional cold storage accumulators 9.
  • the apparatus 1 may comprise less or more than three additional cold storage accumulators 9, depending on the temperature range desired inside the case 2 and the first compartment 5.
  • the working cold storage accumulator 7 and the additional cold storage accumulators 9 can contain an eutectic fluid able to freeze in a refrigerating equipment such as a freezer and which are then able to absorb heat from their surrounding environment.
  • the working cold storage accumulator 7 and the additional cold storage accumulators 9 are intended to maintain at least the first compartment 5 at a predetermined temperature range; for example for vaccines, this temperature range should be between 2°C and 8°C for preserving the integrity and efficacy of the vaccines contained in the drug containers 100.
  • these compartments are preferably insulated.
  • this second compartment 6 is insulated independently from the first compartment 5, and from the third compartment 8.
  • the second compartment 6 is preferably closed by an insulated top lid 6a
  • the third compartment 8 is closed by a different insulated U-shaped top lid 8a.
  • the first compartment 5 is provided with an insulated top wall 5a provided with a handle 5b and fixed to a support 14 receiving the drug containers 100.
  • the handle 5b allows pulling the support 14 out of the first compartment 5 in order to proceed to the removal of one or more selected drug container(s) 100 to be treated (see Figure 7 ).
  • the top lids (6a, 8a) and the top wall 5a also form a protection of the compartments from outside contaminants.
  • the cover 4 of the apparatus 1 of Figure 1 With reference to Figure 3 is shown the cover 4 of the apparatus 1 of Figure 1 , once this cover 4 has been removed from the case 2, with its outer face 4a facing the ground.
  • the cover 4 has the global shape of a bidimensional plate member provided with curved edges.
  • On the inner face 4b of the cover 4 is designed a substantially plane area 10.
  • this substantially plane area 10 is provided with four corner projections 11 positioned so as to define a rectangular print 11a within the plane area 10. As shown below, these four corner projections 11 are dimensioned and shaped so as to form snap-fitting means for temporarily securing the rectangular pack forming the working cold storage accumulator 7.
  • the plane area 10 is further provided with four annular rims, two small annular rims12 and two large annular rims 13.
  • the two small annular rims 12 have a diameter substantially corresponding to the diameter of a small-sized drug container 101 (see Figures 8-9 ) and are dimensioned and shaped so as to form releasable fixing means for temporarily securing such small-sized drug containers 101 to the plane area 10, while the two large annular rims 13 have a diameter substantially corresponding to the diameter of a large-sized drug container 102 (see Figures 8-9 ) and are dimensioned and shaped so as to form releasable fixing means for temporarily securing such large-sized drug containers 102 to the plane area 10.
  • the four annular rims (12, 13) are located adjacent to the corner projections 11 while leaving the rectangular print 11a free. As shown later with reference to Figures 8 and 9 , when the working cold storage accumulator 7 is snap-fitted into the corner projections 11 of the plane area 10 and the drug containers (101, 102) are secured to the plane area 10 via the annular rims (12, 13), the working cold storage acumulator 7 may then protect the drug containers (101, 102) from the excessive outside temperature during a significant period of time, in particular, during the time required for a healthcare worker to withdraw the doses of product from the drug containers (101, 102) and prepare and realize the adequate injections.
  • the apparatus 1 is further provided with a holding strap 15.
  • This holding strap 15 allows a healthcare worker to carry the apparatus 1 easily, on one shoulder for example.
  • the holding strap is designed in order to carry the apparatus as a backpack.
  • the apparatus is free of holding strap.
  • the cover 4 is slidingly connected to the holding strap 15.
  • a healthcare worker is provided with the apparatus 1 in a storage mode, as shown on Figures 1 and 2 , as described above.
  • the inner face 4b of the cover 4, onto which is designed the plane area 10 faces the inside of the case 2.
  • the plane area 10 is therefore protected from the outside environment, and in particular from ambiant air and outside contaminants, and is therefore not in a working configuration.
  • the healthcare worker When the healthcare worker has reached the location of the vaccination where electrical power may be absent or scarce and where people need to be vaccinated, he opens the case 2 by removing the cover 4. As the cover 4 is slidingly connected to the holding strap 15, the healthcare worker causes the cover 4 to move along the holding strap 15 until he can position the outer face 4a of the cover 4 on the ground, as shown on Figure 5 . In this position of the cover 4, the plane area 10 is located outside the case 2 and is in its working configuration. In this configuration, the plane area 10 is capable of receiving the working cold storage accumulator 7 in the projection corners 11. For facilitating the next step, the healthcare worker substantially aligns the cover 4 on the ground, so as to substantially align the plane area 10 on a horizontal plane.
  • the healthcare worker then removes the insulated top lid 6a of the second compartment 6 in order to reach the working cold storage accumulator 7. He removes the working cold storage accumulator 7 from the second compartment 6, puts the top lid 6a back in place, and snap-fits the working cold storage accumulator 7 in the four corner projections 11 of the plane area 10.
  • the healthcare worker then pulls on the handle 5b present on the top wall 5a of the support 14, as shown on Figure 7 , and removes for example a small-sized drug container 101 and a large-sized drug container 102 from the support 14. He then snap-fits these drug containers (101, 102) in the corresponding annular rims (12, 13) of the plane area 10, as shown on Figures 8 and 9 .
  • the removal and positioning steps of the working cold storage accumulator 7 and of the drug containers (101, 102) may be completed in a different order : for example, the drug containers may be placed on the plane area 10 before the working cold storage accumulator 7.
  • the plane area is designed on a face of an independent plate member, which is stored inside the case when no operation is to be performed on a selected drug container, and which may be removed from the case when operations are to be performed on selected drug containers.
  • this plate member may be directly stored within the second compartment, with the working cold storage accumulator already snap-fitted on the plane area. In such a case, the plane area and the working cold storage accumulator are removed simultaneously from the case.
  • the apparatus 1 is therefore in a working mode, during which handling of the drug containers (101, 102) may take place. Because the working cold storage accumulator 7 is close to the operated selected drug containers (101, 102), the cooling energy it releases allows protecting the drug containers (101, 102) from the excessive ambiant temperature during the time required for the healthcare worker to proceed to the withdrawal of the doses of product/vaccine. Indeed, the working cold storage accumulator 7 refreshes the ambiant air located around the drug containers (101, 102) and thereby limits the heat transfer to the sensitive product/vaccines contained in these drug containers. The increase in temperature resulting from the removal of the drug containers (101, 102) from the case 2 is therefore limited and the healthcare worker can prepare and inject doses to the patients without damaging the remaining product/vaccines.
  • the plane area 10 could be designed on an independent plate member, capable of being stored inside the case in a storage mode of the apparatus, and provided with means capable of temporarily fixing the plate member onto the outer faces of the top lids (6a, 8a) of the compartments when operations are to be performed on selected drug containers, so that the plate member would be prevented from contacting the ground and would form an additional insulated wall for the inside of the case 2 during the time operations are performed on the drug containers.
  • the healthcare worker removes the working cold storage accumulator 7 from the plane area 10 by disengaging the working cold storage accumulator 7 from the four corner projections 11. He also removes the drug containers (101, 102) from their corresponding annular rims (12, 13). He replaces the working cold storage accumulator 7 and the empty drug containers (101, 102) inside the case 2, replaces the cover 4 on top of the case 2 and closes the opening 3.
  • the apparatus 1 may then be transported to a hospital or to a location provided with electrical power in order to regenerate all the cold storage accumulators (7, 9) and to replace the empty containers by newly filled ones.
  • the apparatus of the invention allows storing, transporting and performing operations on drug containers, such as withdrawing doses of product/vaccine contained in these drug containers, in a simple and safe manner, in remote locations where electrical power is absent or scarce, without having to implement sophisticated technology and energy consumming systems, while maintaining the drug containers at a safe temperature range during all these steps.
  • the plane area could be designed on an outer face of the case wall and provided with a shutter capable of protecting it from the outside atmosphere, heat and contaminants in a storage mode of the apparatus.
EP13305089.8A 2013-01-25 2013-01-25 Appareil pour manipuler des contenants de médicament Withdrawn EP2759789A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP13305089.8A EP2759789A1 (fr) 2013-01-25 2013-01-25 Appareil pour manipuler des contenants de médicament

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP13305089.8A EP2759789A1 (fr) 2013-01-25 2013-01-25 Appareil pour manipuler des contenants de médicament

Publications (1)

Publication Number Publication Date
EP2759789A1 true EP2759789A1 (fr) 2014-07-30

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018137897A1 (fr) * 2017-01-25 2018-08-02 Va-Q-Tec Ag Procédé permettant de préparer un récipient de transport

Citations (7)

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