EP2720601B1 - Endoillumination using decentered fiber launch - Google Patents
Endoillumination using decentered fiber launch Download PDFInfo
- Publication number
- EP2720601B1 EP2720601B1 EP12822713.9A EP12822713A EP2720601B1 EP 2720601 B1 EP2720601 B1 EP 2720601B1 EP 12822713 A EP12822713 A EP 12822713A EP 2720601 B1 EP2720601 B1 EP 2720601B1
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- Prior art keywords
- fiber
- probe
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- nano
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- 239000000835 fiber Substances 0.000 title claims description 49
- 238000005286 illumination Methods 0.000 claims description 45
- 239000000523 sample Substances 0.000 claims description 39
- 239000013307 optical fiber Substances 0.000 claims description 17
- 230000008878 coupling Effects 0.000 description 5
- 238000010168 coupling process Methods 0.000 description 5
- 238000005859 coupling reaction Methods 0.000 description 5
- 238000000034 method Methods 0.000 description 4
- 230000000295 complement effect Effects 0.000 description 3
- 238000001356 surgical procedure Methods 0.000 description 2
- 230000000712 assembly Effects 0.000 description 1
- 238000000429 assembly Methods 0.000 description 1
- 238000005253 cladding Methods 0.000 description 1
- 238000003780 insertion Methods 0.000 description 1
- 230000037431 insertion Effects 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 229910052724 xenon Inorganic materials 0.000 description 1
- FHNFHKCVQCLJFQ-UHFFFAOYSA-N xenon atom Chemical compound [Xe] FHNFHKCVQCLJFQ-UHFFFAOYSA-N 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
- A61B1/06—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements
- A61B1/07—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements using light-conductive means, e.g. optical fibres
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
- A61B3/0008—Apparatus for testing the eyes; Instruments for examining the eyes provided with illuminating means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
- A61B90/30—Devices for illuminating a surgical field, the devices having an interrelation with other surgical devices or with a surgical procedure
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B6/00—Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings
- G02B6/24—Coupling light guides
- G02B6/42—Coupling light guides with opto-electronic elements
- G02B6/4201—Packages, e.g. shape, construction, internal or external details
- G02B6/4204—Packages, e.g. shape, construction, internal or external details the coupling comprising intermediate optical elements, e.g. lenses, holograms
- G02B6/4206—Optical features
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
- A61B1/00163—Optical arrangements
- A61B1/00165—Optical arrangements with light-conductive means, e.g. fibre optics
- A61B1/0017—Details of single optical fibres, e.g. material or cladding
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
- A61B90/30—Devices for illuminating a surgical field, the devices having an interrelation with other surgical devices or with a surgical procedure
- A61B2090/306—Devices for illuminating a surgical field, the devices having an interrelation with other surgical devices or with a surgical procedure using optical fibres
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
- F04C—ROTARY-PISTON, OR OSCILLATING-PISTON, POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; ROTARY-PISTON, OR OSCILLATING-PISTON, POSITIVE-DISPLACEMENT PUMPS
- F04C2270/00—Control; Monitoring or safety arrangements
- F04C2270/04—Force
- F04C2270/041—Controlled or regulated
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B6/00—Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings
- G02B6/24—Coupling light guides
- G02B6/36—Mechanical coupling means
- G02B6/3616—Holders, macro size fixtures for mechanically holding or positioning fibres, e.g. on an optical bench
- G02B6/3624—Fibre head, e.g. fibre probe termination
Definitions
- Embodiments described herein relate to the field of microsurgical probes. More particularly, embodiments described herein are related to the field of endoillumination using decentered fiber launch.
- microsurgical procedures are evolving rapidly. Typically, these procedures involve the use of probes that are capable of reaching the tissue that is being treated or diagnosed. Such procedures make use of endoscopic surgical instruments having a probe coupled to a controller device in a remote console.
- Current state of the art probes are quite complex in operation, often times requiring moving parts that are operated using complex mechanical systems. In many cases, an electrical motor is included in the design of the probe.
- Most of the prior art devices have a cost that makes them difficult to discard after one or only a few surgical procedures.
- the complexity of prior art devices leads generally to probes having cross sections of several millimeters. These probes are of little practical use for ophthalmic microsurgical techniques. In ophthalmic surgery, dimensions of one (1) mm or less are preferred, to access areas typically involved without damaging unrelated tissue.
- endoilluminators for the interior of the eye face additional challenges.
- the endoilluminator must couple efficiently to the probe to provide enough light energy to reach the interior of the eye.
- the probe tip is so small, the light must be able to spread over a wide solid angle to illuminate the surgical field (ideally corresponding to an in-plane angle of seventy degrees or greater). Both of these considerations have made it difficult to produce small gauge endoilluminators.
- an endoilluminator system includes an endoilluminator probe and an illumination source.
- the endoilluminator probe includes a nano-scale optical fiber and a probe fiber connector
- the illumination source includes a source fiber connector.
- the illumination source is configured to produce an illumination spot at the source fiber connector having a diameter smaller than a diameter of a fiber core of the nano-scale optical fiber.
- the probe fiber connector and the source connector are configured when connected to align the illumination spot off-center relative to the nano-scale optical fiber such that the angular distribution of light emitted by the nano-scale optical fiber is increased relative to aligning the illumination spot at a center of the nano-scale optical fiber.
- Various embodiments of the present invention provide a fiber connector system with a decentered launch of light beams into the probe optical fiber.
- Certain embodiments include a source fiber connector and a probe fiber connector, wherein an illumination spot emitted from the source fiber connector is offset from a center of the probe fiber.
- the connectors can hold the central axes of the source emitter and the probe fiber offset relative to one another.
- the source emitter can be configured to emit an illumination spot off center relative to the probe fiber. Additional features of various embodiments of the present invention are described in the following explanation of the FIGS.
- Various embodiments of the present invention provide improve endoi!lumination by increasing the angular distribution of the illuminated area using a decentered launch while providing equivalent or greater coupling efficiency for the illumination source to the probe.
- Previous systems have centered the illumination spot on the probe fiber in order to avoid significant drops in coupling efficiency, therefore making less light available for illumination.
- the spot can be decentered without significant illumination loss. The decentration does, however, significantly increase the angular distribution of the illumination, thus allowing a wider area to be illuminated with substantially equal brightness.
- the illumination spot produced by the illumination source can be relatively large, meaning that decentering the spot produces significantly less illumination.
- illuminator systems using a tightly focused spot according to various embodiments of the present invention are used, decentration can be exploited for a larger angular distribution without such losses.
- various embodiments of the present invention may be particularly useful for illumination sources that produce tightly focused illumination spots, such as supercontinuum lasers.
- FIG. 1 which includes an endoprobe 10 with a handle 12 having a length L1 suitable for being held in a single hand and cannula 14 having a diameter D and length L2.
- the endoprobe 10 is optically coupled to an illumination source 16 by a probe fiber connector 104 connected to a source fiber connector 102.
- the diameter D of the cannula 14 is typically measured in according to the gauge system for needles and similar medical devices; for ophthalmic applications, this is typically 20 Ga (0.84 mm) or less. While the discussion relates to ophthalmic endoilluminators, it could also apply to similar endoillumination devices that are inserted through small incisions to produce wide-angle illumination. For purposes of this specification, "small gauge” will be used to refer to endoilluminators of 20 Ga diameter or less, and “nano-scale” will be used to refer to optical fibers having an outer diameter of 100 ⁇ m or less.
- FIGs 2A and 2B illustrate end views of complementary fiber connectors 102 and 104 according to a particular embodiment of the present invention.
- the source connector 102 includes a bulkhead 106 for holding a probe fiber connector 104 in alignment with the illumination spot 108 produced by the illumination source 20.
- the location of the illumination spot 108 is focused off- center relative to the bulkhead 106, so that when the probe fiber connector 104 is centered by the bulkhead, the illumination spot 108 will enter a fiber core 110 of a probe optical fiber (including core 110 and cladding 112) decentered.
- FIGs. 3A and 3B An alternative embodiment is illustrated in FIGs. 3A and 3B .
- the probe fiber is positioned off-center in the probe fiber connector 104.
- the probe fiber connector 104 When the probe fiber connector 104 is inserted into the bulkhead, it is automatically aligned so that a centered illumination spot 108 from the illumination source 20 will be off-center relative to the fiber core 110 of the probe fiber, as shown in FIG. 4B.
- the alignment of the source fiber connector 102 and the probe fiber connector 104 produces a decentered launch of illumination light into the probe fiber.
- FIG. 4 illustrates the in-plane angular distribution to full-width at half maximum (FWHM) of light intensity as measured from an example probe fiber into which an illumination spot is aligned for a decentered launch into the fiber.
- FWHM full-width at half maximum
- light emitted from an endoilluminator will be considered as having an "angular distribution" of a certain angle if the in-plane angular distribution to FWHM spans that angle.
- the illumination spot size is about 1 ⁇ m into a fiber having a numerical aperture of 0.22.
- the plot illustrates that for decentration of up to 20 ⁇ m, the angular distribution out to which the FWHM extends rises from about 70 degrees to nearly 90 degrees.
- FIG. 5 illustrates the coupling efficiency for the same optical fiber as a function of decentration.
- decentration of the illumination spot coupled into the fiber can actually increase slightly as long as the illumination spot still falls onto the fiber core, falling off only when the spot moves off of the fiber core.
- the decentered alignment of the endoilluminator system may provide a larger angular distribution without even needing to make the relatively minor tradeoff between brightness and angular intensity.
- Various embodiments of the present invention provide an endoilluminator system including fiber connectors providing a decentered alignment between an illumination spot and a probe optical fiber.
- fiber connectors providing a decentered alignment between an illumination spot and a probe optical fiber.
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Surgery (AREA)
- Physics & Mathematics (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Medical Informatics (AREA)
- Pathology (AREA)
- Biophysics (AREA)
- Optics & Photonics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Physics & Mathematics (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Ophthalmology & Optometry (AREA)
- Radiology & Medical Imaging (AREA)
- Optical Couplings Of Light Guides (AREA)
- Laser Surgery Devices (AREA)
- Non-Portable Lighting Devices Or Systems Thereof (AREA)
- Mechanical Coupling Of Light Guides (AREA)
- Instruments For Viewing The Inside Of Hollow Bodies (AREA)
- Dental Tools And Instruments Or Auxiliary Dental Instruments (AREA)
Description
- This application claims priority to
U.S. provisional application Serial No. 61/521,450, filed on August 9, 2011 - Embodiments described herein relate to the field of microsurgical probes. More particularly, embodiments described herein are related to the field of endoillumination using decentered fiber launch.
- The field of microsurgical procedures is evolving rapidly. Typically, these procedures involve the use of probes that are capable of reaching the tissue that is being treated or diagnosed. Such procedures make use of endoscopic surgical instruments having a probe coupled to a controller device in a remote console. Current state of the art probes are quite complex in operation, often times requiring moving parts that are operated using complex mechanical systems. In many cases, an electrical motor is included in the design of the probe. Most of the prior art devices have a cost that makes them difficult to discard after one or only a few surgical procedures. Furthermore, the complexity of prior art devices leads generally to probes having cross sections of several millimeters. These probes are of little practical use for ophthalmic microsurgical techniques. In ophthalmic surgery, dimensions of one (1) mm or less are preferred, to access areas typically involved without damaging unrelated tissue.
- Because of the relatively small aperture, endoilluminators for the interior of the eye face additional challenges. First, the endoilluminator must couple efficiently to the probe to provide enough light energy to reach the interior of the eye.
- Second, because the probe tip is so small, the light must be able to spread over a wide solid angle to illuminate the surgical field (ideally corresponding to an in-plane angle
of seventy degrees or greater). Both of these considerations have made it difficult to produce small gauge endoilluminators. -
US 2009/232438 A1 ,WO 2005/067573 A2 ,US 2005/259916 A1 , andEP 1,039321 A2 are representative of the present state of the art. - The present invention provides an endoilluminator system in accordance with claims which follow. According to particular embodiments of the present invention, an endoilluminator system includes an endoilluminator probe and an illumination source. The endoilluminator probe includes a nano-scale optical fiber and a probe fiber connector, and the illumination source includes a source fiber connector. The illumination source is configured to produce an illumination spot at the source fiber connector having a diameter smaller than a diameter of a fiber core of the nano-scale optical fiber. The probe fiber connector and the source connector are configured when connected to align the illumination spot off-center relative to the nano-scale optical fiber such that the angular distribution of light emitted by the nano-scale optical fiber is increased relative to aligning the illumination spot at a center of the nano-scale optical fiber.
- These and other embodiments of the present invention will be described in further detail below with reference to the following drawings.
-
-
FIG 1 shows a schematic of an ophthalmic endoilluminator system according to a particular embodiment of the present invention; -
FIGs. 2 A and 2B illustrate end views of complementary fiber connectors according to a particular embodiment of the present invention; -
FIGs. 3A and 3B illustrate end views of complementary fiber connectors according to an alternative embodiment of the present invention; -
FIG 4 is a graph illustrating the in-plane illumination angle corresponding to full-width at half maximum intensity for various amounts of decentration for a probe according to a particular embodiment of the present invention; and -
FIG. 5 is a graph illustrating coupling efficiency for various amounts of decentration for a probe according to a particular embodiment of the present invention. - In the figures, elements having the same reference number have the same or similar functions.
- Various embodiments of the present invention provide a fiber connector system with a decentered launch of light beams into the probe optical fiber. Certain embodiments include a source fiber connector and a probe fiber connector, wherein an illumination spot emitted from the source fiber connector is offset from a center of the probe fiber. For example, the connectors can hold the central axes of the source emitter and the probe fiber offset relative to one another. In another example, the source emitter can be configured to emit an illumination spot off center relative to the probe fiber. Additional features of various embodiments of the present invention are described in the following explanation of the FIGS.
- Various embodiments of the present invention provide improve endoi!lumination by increasing the angular distribution of the illuminated area using a decentered launch while providing equivalent or greater coupling efficiency for the illumination source to the probe. Previous systems have centered the illumination spot on the probe fiber in order to avoid significant drops in coupling efficiency, therefore making less light available for illumination. However, when using sufficiently small illumination spots and, in particular, when using illumination spots that can be decentered and still fall within the fiber cross-section, the spot can be decentered without significant illumination loss. The decentration does, however, significantly increase the angular distribution of the illumination, thus allowing a wider area to be illuminated with substantially equal brightness.
- In previous systems, particularly xenon lamp assemblies, the illumination spot produced by the illumination source can be relatively large, meaning that decentering the spot produces significantly less illumination. By contrast, when illuminator systems using a tightly focused spot according to various embodiments of the present invention are used, decentration can be exploited for a larger angular distribution without such losses. Thus, various embodiments of the present invention may be particularly useful for illumination sources that produce tightly focused illumination spots, such as supercontinuum lasers.
- In general, the following description relates to ophthalmic surgical endoprobes including a handle suitable for being held in one hand and a cannula that is at least partially rigid that is suitable for insertion into a small incision. Such a
system is schematically illustrated inFIG. 1 , which includes anendoprobe 10 with ahandle 12 having a length L1 suitable for being held in a single hand andcannula 14 having a diameter D and length L2. Theendoprobe 10 is optically coupled to anillumination source 16 by aprobe fiber connector 104 connected to asource fiber connector 102. The diameter D of thecannula 14 is typically measured in according to the gauge system for needles and similar medical devices; for ophthalmic applications, this is typically 20 Ga (0.84 mm) or less. While the discussion relates to ophthalmic endoilluminators, it could also apply to similar endoillumination devices that are inserted through small incisions to produce wide-angle illumination. For purposes of this specification, "small gauge" will be used to refer to endoilluminators of 20 Ga diameter or less, and "nano-scale" will be used to refer to optical fibers having an outer diameter of 100 µm or less. -
FIGs 2A and 2B illustrate end views ofcomplementary fiber connectors source connector 102 includes abulkhead 106 for holding aprobe fiber connector 104 in alignment with theillumination spot 108 produced by theillumination source 20. The location of theillumination spot 108 is focused off- center relative to thebulkhead 106, so that when theprobe fiber connector 104 is centered by the bulkhead, theillumination spot 108 will enter afiber core 110 of a probe optical fiber (includingcore 110 and cladding 112) decentered. - An alternative embodiment is illustrated in
FIGs. 3A and 3B . InFIGs. 3A and 3B , the probe fiber is positioned off-center in theprobe fiber connector 104. When theprobe fiber connector 104 is inserted into the bulkhead, it is automatically aligned so that a centeredillumination spot 108 from theillumination source 20 will be off-center relative to thefiber core 110 of the probe fiber, as shown in FIG. 4B. Thus, the alignment of thesource fiber connector 102 and theprobe fiber connector 104 produces a decentered launch of illumination light into the probe fiber. -
FIG. 4 illustrates the in-plane angular distribution to full-width at half maximum (FWHM) of light intensity as measured from an example probe fiber into which an illumination spot is aligned for a decentered launch into the fiber. For purposes of this specification, light emitted from an endoilluminator will be considered as having an "angular distribution" of a certain angle if the in-plane angular distribution to FWHM spans that angle. The illumination spot size is about 1 µm into a fiber having a numerical aperture of 0.22. The plot illustrates that for decentration of up to 20 µm, the angular distribution out to which the FWHM extends rises from about 70 degrees to nearly 90 degrees. -
FIG. 5 illustrates the coupling efficiency for the same optical fiber as a function of decentration. As shown in the plot ofFIG. 5 , decentration of the illumination spot coupled into the fiber can actually increase slightly as long as the illumination spot still falls onto the fiber core, falling off only when the spot moves off of the fiber core. Given the higher coupling efficiency and angular distribution, the decentered alignment of the endoilluminator system may provide a larger angular distribution without even needing to make the relatively minor tradeoff between brightness and angular intensity. - Various embodiments of the present invention provide an endoilluminator system including fiber connectors providing a decentered alignment between an illumination spot and a probe optical fiber. Embodiments of the invention described above are exemplary only.
Claims (6)
- An endoilluminator system, comprising:an endoilluminator probe (10) comprising a nano-scale optical fiber having an outer diameter of 100 µm or less and a probe fiber connector (104);an illumination source (20) comprising a source fiber connector (102), the illumination source configured to produce an illumination spot (108) at the source fiber connector (102), the illumination spot having a diameter smaller than a diameter of a fiber core (110) of the nano-scale optical fiber,characterized in that the illumination spot (108) has a diameter of about 1 µm, the probe fiber connector (104) and the source connector (102) being adapted to be connected to align the illumination spot off-center relative to the fiber core (110) of the nano-scale optical fiber such that the angular distribution of light emitted by the nano-scale optical fiber is increased relative to aligning the illumination spot at a center of the nano-scale optical fiber.
- The endoilluminator system of Claim 1, wherein the illumination spot (108) is aligned off-center by at least 10 percent of the diameter of the fiber core (110) of the nano-scale optical fiber.
- The endoilluminator system of Claim 1, wherein the illumination source (20) is a supercontinuum laser.
- The endoilluminator system of Claim 1, wherein the nano-scale optical fiber is aligned off-center within the probe fiber connector (104).
- The endoilluminator system of Claim 1, wherein the illumination spot (108) is produced at the source fiber connector (102) off-center relative to a bulkhead (106) of the source fiber connector.
- The endoilluminator system of Claim 1, wherein an angular distribution of the endoilluminator probe (10) is at least eighty degrees.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201161521450P | 2011-08-09 | 2011-08-09 | |
PCT/US2012/050180 WO2013023080A1 (en) | 2011-08-09 | 2012-08-09 | Endoillumination using decentered fiber launch |
Publications (3)
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EP2720601A1 EP2720601A1 (en) | 2014-04-23 |
EP2720601A4 EP2720601A4 (en) | 2015-01-21 |
EP2720601B1 true EP2720601B1 (en) | 2017-05-03 |
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Application Number | Title | Priority Date | Filing Date |
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EP12822713.9A Active EP2720601B1 (en) | 2011-08-09 | 2012-08-09 | Endoillumination using decentered fiber launch |
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US (1) | US9730576B2 (en) |
EP (1) | EP2720601B1 (en) |
JP (1) | JP6114272B2 (en) |
CN (1) | CN103732122B (en) |
AU (1) | AU2012294363B2 (en) |
CA (1) | CA2842435C (en) |
ES (1) | ES2628304T3 (en) |
WO (1) | WO2013023080A1 (en) |
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US9849034B2 (en) | 2011-11-07 | 2017-12-26 | Alcon Research, Ltd. | Retinal laser surgery |
US9097616B2 (en) * | 2013-01-25 | 2015-08-04 | Hewlett-Packard Development Company, L.P. | Apparatus for collecting material to be spectrally analyzed |
US9572629B1 (en) * | 2015-08-31 | 2017-02-21 | Novartis Ag | Sub-micron alignment of a monitoring fiber for optical feedback in an ophthalmic endo-illumination system |
US10918522B2 (en) | 2017-06-08 | 2021-02-16 | Alcon Inc. | Photodisruption-based vitrectomy system |
JP2022513453A (en) * | 2018-12-13 | 2022-02-08 | アイオーピーティマ リミテッド | Minimally Invasive AB-INTERNO Methods and Systems for Laser Assisted Technology for Glaucoma Surgery |
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US4870952A (en) * | 1983-10-28 | 1989-10-03 | Miquel Martinez | Fiber optic illuminator for use in surgery |
JPH0434504A (en) * | 1990-05-31 | 1992-02-05 | Furukawa Electric Co Ltd:The | Optical fiber for detecting gas, liquid or the like |
US5230555A (en) | 1991-08-30 | 1993-07-27 | Progressive Dynamics, Inc. | Fiber optic arc lamp system |
EP1039321A2 (en) | 1999-03-24 | 2000-09-27 | Lucent Technologies Inc. | Optical fiber ferrule apparatus |
US6478478B1 (en) | 2000-12-04 | 2002-11-12 | Patrick J. Campbell | Fiber-optic connector |
EP1356328B8 (en) | 2000-12-21 | 2011-02-02 | Light Prescriptions Innovators, LLC. | Light conduit with radial light ejecting structure |
JP2002231008A (en) * | 2001-02-05 | 2002-08-16 | Matsushita Electric Works Ltd | Lighting device |
US7231114B2 (en) | 2003-05-21 | 2007-06-12 | Ocp-Europe, Ltd. | Multimode fiber optical fiber transmission system with offset launch single mode long wavelength vertical cavity surface emitting laser transmitter |
JP2005168770A (en) * | 2003-12-10 | 2005-06-30 | Olympus Corp | Endoscope |
US7228032B2 (en) * | 2004-01-12 | 2007-06-05 | Xponent Photonics Inc. | Apparatus and methods for launching an optical signal into multimode optical fiber |
US7265840B2 (en) | 2005-06-16 | 2007-09-04 | Matsushita Electric Industrial Co., Ltd. | Coupling method for coupling high power optical beams into an optical waveguide |
US20090175576A1 (en) | 2008-01-08 | 2009-07-09 | Cornova, Inc. | Shaped fiber ends and methods of making same |
JP5224445B2 (en) | 2008-03-17 | 2013-07-03 | 富士フイルム株式会社 | Laser light source device |
CN201352265Y (en) * | 2008-11-21 | 2009-11-25 | 深圳市大族激光科技股份有限公司 | Optical fiber transmission device |
JP5388732B2 (en) * | 2009-07-15 | 2014-01-15 | Hoya株式会社 | Medical observation system and processor |
US20110085348A1 (en) | 2009-10-13 | 2011-04-14 | Dobson Paul J | LED light source for fiber optic cable |
EP2498666B1 (en) * | 2009-11-11 | 2014-07-02 | Alcon Research, Ltd. | Structured illumination probe |
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- 2012-08-09 CA CA2842435A patent/CA2842435C/en not_active Expired - Fee Related
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- 2012-08-09 EP EP12822713.9A patent/EP2720601B1/en active Active
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US9730576B2 (en) | 2017-08-15 |
CN103732122A (en) | 2014-04-16 |
EP2720601A4 (en) | 2015-01-21 |
WO2013023080A1 (en) | 2013-02-14 |
ES2628304T3 (en) | 2017-08-02 |
CA2842435A1 (en) | 2013-02-14 |
JP2014528760A (en) | 2014-10-30 |
CN103732122B (en) | 2017-02-22 |
JP6114272B2 (en) | 2017-04-12 |
EP2720601A1 (en) | 2014-04-23 |
AU2012294363A1 (en) | 2014-02-06 |
US20130041233A1 (en) | 2013-02-14 |
CA2842435C (en) | 2019-09-03 |
AU2012294363B2 (en) | 2017-02-16 |
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