EP2583752B1 - Laminare Strömungsvorrichtung - Google Patents

Laminare Strömungsvorrichtung Download PDF

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Publication number
EP2583752B1
EP2583752B1 EP11186082.1A EP11186082A EP2583752B1 EP 2583752 B1 EP2583752 B1 EP 2583752B1 EP 11186082 A EP11186082 A EP 11186082A EP 2583752 B1 EP2583752 B1 EP 2583752B1
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EP
European Patent Office
Prior art keywords
laminar flow
flow device
containing part
air
temperature
Prior art date
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Not-in-force
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EP11186082.1A
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English (en)
French (fr)
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EP2583752A1 (de
Inventor
Yang-Te Hsu
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Individual
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Individual
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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L1/00—Enclosures; Chambers
    • B01L1/04—Dust-free rooms or enclosures

Definitions

  • the present invention relates to a laminar flow device and, more particularly, to a laminar flow device capable of providing a low-temperature, dustless, and aseptic environment.
  • bio-trials are usually carried out in an environment of particular conditions such as low-temperature, dustlessness and asepsis, so as to protect the experimenter and lower the error of result due to the external contaminants.
  • bio-trails such as protein extraction, cytological trial and histo-trial has to be performed at a low temperature, and some of them performed with enzymes or specific reagents have even to be processed in a critical range of low temperature to avoid disadvantages due to external and high temperature and humidity such as protein degradation, inactive enzyme, and cell/tissue degeneration.
  • protein extraction is performed by pouring a desired number of fragmental ice blocks into a container and then inserting a test tube that receives cells or tissues between the ice blocks in the container, so as to perform the protein extraction.
  • a test tube may not be firmly positioned by the ice blocks since the ice blocks may melt into water, and thus the liquid with the cells or tissues may be poured out or contaminated.
  • the container should be big enough to receive a lot of ice when it takes much time for processing the bio-trail.
  • this big container may be bigger than the capacity of a conventional laminar flow device, and a test tube exposed to the air in a normal room may be contaminated by the floating dust. Therefore, a new laminar flow device is needed to solve the above problems.
  • FR 2 497 826 A1 describes a fume hood comprising a processing chamber which is connected via an opening to a germicide conduit, wherein air from the processing chamber is sucked by a turbine and fed to the germicide conduit form where the sterilized air is guided back into the processing chamber.
  • DE 36 32 276 A1 , WO 2008/128360 A1 , US 6,374,621 B1 and DE 24 20 644 A1 are examples for processing chambers being provided with a tempering portion, wherein air is released from the processing chamber towards the tempering unit and guided backwards to the processing chamber after being tempered.
  • Another objective of this invention is providing a laminar flow device to establish a dustless and aseptic environment for bio-trial, so as to avoid floating dust.
  • Still another objective of this invention is providing a laminar flow device to save the cost and additional time, water and power consumption for manufacture of ice blocks.
  • the invention discloses a laminar flow device including a containing body and an air circulating unit.
  • the containing body is separated into a first containing part and a second containing part, with a surrounding wall of the first containing part having a processing window, with a cover being capable of sealing the processing window, and with the cover having a transparent part.
  • the air circulating unit is received in the second containing part and expels low-temperature air into the first containing part.
  • the invention further discloses that the first and second containing parts are separated by a partition, the first containing part has a processing room and the second containing part has a receiving room in communication with the processing room, and two openings are formed in the partition for airflow to pass through.
  • the invention further discloses that the transparent part is made of a transparent material, and a plurality of defogger lines is formed on the transparent part.
  • the invention further discloses that a light emitting member is mounted on the inner wall of the first containing part and the light emitting member comprises an ultraviolet sterilizer and an illuminative light, with the ultraviolet sterilizer capable of irradiating UV light and the illuminative light capable of irradiating visible light respectively.
  • the air circulating unit comprises a compressor module, a temperature-regulating module and an autoclave-sterilizing module, which are all positioned on the partition, with the temperature-regulating module arranged at one of the two openings to inhale the air in the processing room, and with the autoclave-sterilizing module arranged at the other opening and sterilizing the inhaled air.
  • the invention further discloses that an air tube is further comprised, wherein the air tube has an end connecting with the autoclave-sterilizing module and another end communicating with the processing room to expel the low-temperature air.
  • the invention further discloses that the cover is pivotably coupled with an edge defining the processing window.
  • the invention further discloses that the cover is coupled with a balancing module.
  • the invention further discloses that the balancing module comprises a chain, a gear wheel set and a weight, two ends of the chain are respectively connected with the cover and the weight, and the gear wheel set movably hold the chain for the chain to slide.
  • the invention further discloses that a controller electrically is connected with the air circulating unit and attached to an outer face of the second containing part.
  • the invention further discloses that a plurality of wheels is arranged beneath the containing body.
  • the invention further discloses that a first auxiliary window and a second auxiliary window in the surrounding wall of the first containing part are formed, with both of the first and second auxiliary windows communicating with the processing room and capable of being sealed by covers.
  • the invention further discloses that the first auxiliary window is formed beneath the processing window while the cover capable of sealing the first auxiliary window is in the form of a sliding door.
  • the invention further discloses that an additional second auxiliary window is formed, with the two second auxiliary windows formed on two opposite sides of the first containing part.
  • the invention further discloses that at least one socket is arranged in the first containing part.
  • Fig. 1 shows a laminar flow device according to a first embodiment of the invention, which includes a containing body 1 and an air circulating unit 2 received inside the containing body 1 to maintain a low-temperature environment in the containing body 1, with the said "low-temperature” having a temperature degree lower than 25°C and preferably between 1-8 °C.
  • the containing body 1 is preferably made of acrylic ester, so as to provide advantages such as light and qualified performances in pressure resistance and high temperature resistance.
  • a partition 11 is positioned inside the containing body 1 to separate the inner room of the containing body 1 into a first containing part 1a and a second containing part 1b, with the first containing part 1a forming a processing room S1 and the second containing part 1b forming a receiving room S2 in communication with the processing room S1.
  • the first containing part 1a is made of transparent and acrylic material.
  • a surrounding wall of the first containing part 1a has a processing window 12 with a cover 13 capable of sealing the processing window 12.
  • the processing window 12 is preferably formed in an inclined face of the surrounding wall for a user to conveniently put objects into the processing room S1 or perform biological processes therein via the processing window 12.
  • the cover 13 is pivotably coupled with an edge defining the processing window 12, while the cover 13 further has a transparent part 131 made of glasses, with a plurality of defogger lines 132 formed on an inner side of the transparent part 131 to heat the cooled surface of the transparent part 131 of the cover 13 for defogging.
  • the inner side of the transparent part 131 can also be formed of a nano surface to avoid the adhesion of sweat.
  • the first containing part 1a there can be at least one light emitting member 14 inside the first containing part 1a, which may include an ultraviolet sterilizer 141 and an illuminative light 142 mounted on the inner wall of the first containing part 1a, preferably mounted on an bottom face of the partition 11, so that the ultraviolet sterilizer 141 and illuminative light 142 can irradiate UV light and visible light respectively in the processing room S1.
  • the light emitting member 14 is mainly provided to produce the UV light and visible light, so that a position in which the light emitting member 14 is arranged can be any position in the first containing part 1a as long as the UV light of the ultraviolet sterilizer 141 and the visible light of the illuminative light 142 can be casted to objects inside the processing room S1.
  • first auxiliary window 15 and a second auxiliary window 16 in the surrounding wall of the first containing part 1a both of them communicating with the processing room S1, while the first auxiliary window 15 can be sealed by a cover 151 and the second auxiliary window 16 can be sealed by another cover 161.
  • first auxiliary window 15 is formed beneath the processing window 12 while the cover 151 is in the form of a sliding door for the user to stretch hands into the processing room S1 through the first auxiliary window 15.
  • the second auxiliary window 16 is formed on a part of the surrounding wall that is adjacent to the inclined face where the processing window 12 formed, and the second auxiliary window 16 is provided for another user to stretch hands into the processing room S1 so as to assist the performance of biological processes.
  • the air circulating unit 2 is received inside the second containing part 1b and expels air with low temperature into the first containing part 1a.
  • the air circulating unit 2 includes a compressor module 21, a temperature-regulating module 22 and an autoclave-sterilizing module 23, which are positioned on the partition 11 and connect with each other.
  • the temperature-regulating module 22 is preferably arranged at one of the openings 111 to inhale the air in the processing room S1, and the autoclave-sterilizing module 23 expels cool and sterilized air into the processing room S1 through the other opening 111.
  • the air inhaled by the temperature-regulating module 22 initially passes through the filter to get rid of the floating dust therein, and then the temperature of the inhaled air is lowered by the temperature-regulating module 22. Finally, the low-temperature air is sterilized by the autoclave-sterilizing module 23 before entering the processing room S1. Additionally, a dehumidifier can be interconnected between the temperature-regulating module 22 and the autoclave-sterilizing module 23.
  • the air circulating unit 2 is adapted to lower the temperature of the inhaled air, preferably to 1-8°C, and to remove dust and to sterilize. Any kind of conventional machine used capable of such functions is suitable for use in this invention, and thus the way in which the air circulating unit 2 performs is not limited.
  • a controller 3 electrically connected with the air circulating unit 2 and preferably attached to an outer face of the second containing part 1b, so that the user can adjust the temperature of the air passing through the air circulating unit 2.
  • the above illustrated laminar flow device has the following advantages.
  • Second, the defogger lines 132 can efficiently prevent the adhesion of sweat caused by temperature difference, so as to provide a clear view for the user when a bio-trail is carried out. Therefore, not only the time consumption and cost for manufacture of fragmental ice blocks are avoided, but a low-temperature, dustless and aseptic environment is maintained, so that the result of the bio-trail is accurate.
  • FIG. 3 which shows a laminar flow device according to a second embodiment of the invention, with this laminar flow device also including a containing body 4 and an air circulating unit 5 received inside the containing body 4 to maintain a low-temperature environment in the containing body 4.
  • the containing body 4 is separated into a first containing part 4a and a second containing part 4b by a partition 41, and a surrounding wall of the first containing part 4a has a processing window 42 with a cover 43 capable of sealing the processing window 42, with the first containing part 4a forming an processing room S1' and the second containing part 4b forming a receiving room S2' in communication with the processing room S1'.
  • the difference between the containing body 4 of this embodiment and the containing body 1 of the first embodiment lies in that the cover 43 of the containing body 4 is coupled with a balancing module 44, and thus the balancing module 44 can keep the position of the cover 43 relative to the processing window 42.
  • the balancing module 44 has a chain 441, a gear wheel set 442 and a weight 443. Two ends of the chain 441 are respectively connected with the cover 43 and the weight 443.
  • the gear wheel set 442 is adapted to movably hold the chain 441 for the chain 441 to slide.
  • the air circulating unit 5 includes a compressor module 51, a temperature-regulating module 52 an an autoclave-sterilizing module 53, so as to expel low-temperature, dustless and aseptic air into the first containing part 4a and maintain the dustless and aseptic environment of the processing room S1'.
  • the difference between the air circulating unit 5 of this embodiment and the air circulating unit 2 of the first embodiment lies in that an additional air tube 54 is used, with an end of the air tube 54 connecting with the autoclave-sterilizing module 53 and the other end of the air tube 54, which serves as a free end 541, communicating with the processing room S1'.
  • the air tube 54 is specifically used to guide the expelled air to a desired part of the processing room S1'.
  • the free end 541 is preferably arranged adjacent to a lower edge of the processing window 42 and jets out the expelled air upwards. Therefore, since the pressure of the expelled air is larger than that of the air outside the containing body 4, the outside air is prevented from entering the containing body 4 via the processing window 42.

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  • Health & Medical Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Apparatus For Disinfection Or Sterilisation (AREA)

Claims (13)

  1. Laminarströmungsvorrichtung, umfassend:
    einen Aufnahmekörper (1, 4), der in einen ersten Aufnahmeabschnitt (1a, 4a) und einen zweiten Aufnahmeabschnitt (1b, 4b) unterteilt ist, wobei eine Umfangswand des ersten Aufnahmeabschnitts (1 a, 4a) ein Bearbeitungsfenster (12, 42) aufweist, wobei eine Abdeckung (13, 43) vorgesehen ist, mit welcher das Bearbeitungsfenster (12, 42) dicht verschlossen werden kann, und wobei die Abdeckung (13, 43) einen transparenten Teil (131, 431) aufweist,
    wobei die Laminarströmungsvorrichtung außerdem eine Luftzirkulationseinheit (2, 5) umfasst, die in dem zweiten Aufnahmeabschnitt (1 b, 4b) aufgenommen ist und derart konfiguriert ist, um Niedertemperaturluft in den ersten Aufnahmeabschnitt (1a, 4a) auszustoßen, wobei die Niedertemperaturluft eine Temperatur zwischen 1 - 8 °C hat,
    wobei der erste und der zweite Aufnahmeabschnitt (1a, 1b, 4a, 4b) durch eine Trennwand (11, 41) voneinander getrennt sind, wobei der erste Aufnahmeabschnitt (1a, 4a) einen Bearbeitungsraum (S1, S1') aufweist, und wobei der zweite Aufnahmeabschnitt (1 b, 4b) einen Aufnahmeraum (S2, S2') aufweist, der mit dem Bearbeitungsraum (S1, S1') in Verbindung steht, wobei zwei Öffnungen (111, 411) zum Hindurchfließen eines Luftstroms in der Trennwand (11, 41) ausgebildet sind,
    wobei die Luftzirkulationseinheit (2, 5) ein Kompressormodul (21, 51), ein Temperaturregelmodul (22, 52) und ein Autoklav-Sterilisationsmodul (23, 53) umfasst, welche alle an der Trennwand (11, 41) positioniert sind und miteinander verbunden sind, wobei das Temperaturregelmodul (22, 52) an einer der beiden Öffnungen (111, 411) angeordnet ist, um die Luft in den Bearbeitungsraum (S1, S1') anzusaugen, und wobei das Autoklav-Sterilisationsmodul (23, 53) an der anderen Öffnung (111, 411) angeordnet ist und die angesaugte Luft vor dem Eintritt in den Bearbeitungsraum (S1, S1') sterilisiert.
  2. Laminarströmungsvorrichtung nach Anspruch 1, bei welcher der transparente Teil (131, 431) aus einem transparenten Material hergestellt ist, wobei eine Mehrzahl von Antibeschlagslinien (132, 432) an dem transparenten Teil (131, 431) ausgebildet ist.
  3. Laminarströmungsvorrichtung nach Anspruch 1, bei welcher ein lichtemittierendes Element (14, 45) an der Innenwand des ersten Aufnahmeabschnitts (1a, 4a) montiert ist, wobei das lichtemittierende Element (14, 45) einen Ultraviolett-Sterilisator (141, 451) und eine Beleuchtungslichtquelle (142, 452) beinhaltet, wobei der Ultraviolett-Sterillsator (141, 451) zur Ausstrahlung von UV-Licht imstande ist, und wobei die Beleuchtungslichtquelle (142, 452) entsprechend zur Ausstrahlung von sichtbarem Licht imstande ist.
  4. Laminarströmungsvorrichtung nach Anspruch 1, welche ferner eine Belüftungsleitung (54) umfasst, wobei die Belüftungsleitung (54) ein mit dem Autoklav-Sterillsationsmodul (53) verbundenes Ende und ein anderes mit dem Bearbeitungsraum (S1') in Verbindung stehendes Ende zum Ausstoß der Niedertemperaturluft aufweist, wobei die Niedertemperaturluft eine Temperatur zwischen 1 - 8 °C hat.
  5. Laminarströmungsvorrichtung nach Anspruch 1, bei welcher die Abdeckung (13, 43) schwenkbar mit einem Rand gekoppelt ist, der das Bearbeitungsfenster (12, 42) begrenzt.
  6. Laminarströmungsvorrichtung nach Anspruch 1, bei welcher die Abdeckung (43) mit einem Ausgleichsmodul (44) gekoppelt ist.
  7. Laminarströmungsvorrichtung nach Anspruch 6, bei welcher das Ausgleichsmodul (44) eine Kette (441), einen Zahnradsatz (442) und ein Gewicht (443) umfasst, wobei die beiden Enden der Kette (441) jeweils mit der Abdeckung (43) und dem Gewicht (443) verbunden sind, und wobei der Zahnradsatz (442) die Kette (441) beweglich lagert, sodass die Kette (441) gleiten kann.
  8. Laminarströmungsvorrichtung nach Anspruch 1, welche ferner einen Kontroller (3) umfasst, der elektrisch mit der Luftzirkulationseinheit (2, 5) verbunden ist und an einer Außenfläche des zweiten Aufnahmeabschnitts (1b, 4b) angebracht ist.
  9. Laminarströmungsvorrichtung nach Anspruch 1, bei welcher eine Mehrzahl an Rädern (18) unterhalb des Aufnahmekörpers (1) angeordnet ist.
  10. Laminarströmungsvorrichtung nach Anspruch 1, bei welcher ein erstes Hilfsfenster (15) und ein zweites Hilfsfenster (16) in der Umfangswand des ersten Aufnahmeabschnitts (1b) ausgebildet sind, wobei sowohl das erste als auch das zweite Hilfsfenster (15, 16) mit dem Bearbeitungsraum (S1) in Verbindung stehen und durch Abdeckungen (151, 161) dicht verschließbar sind.
  11. Laminarströmungsvorrichtung nach Anspruch 10, bei welcher das erste Hilfsfenster (15) unterhalb des Bearbeitungsfensters (12) ausgebildet ist, wobei die Abdeckung (151), die zum Verschließen des ersten Hilfsfensters (15) dient, in Form einer Schiebetür ausgebildet ist.
  12. Laminarströmungsvorrichtung nach Anspruch 10, bei welcher ein zusätzliches zweites Hilfsfenster (16) vorgesehen ist, wobei die beiden zweiten Hilfsfenster (16) an zwei gegenüberliegenden Seiten des ersten Aufnahmeabschnitts (1 a) ausgebildet sind.
  13. Laminarströmungsvorrichtung nach Anspruch 1, bei welcher wenigstens eine Steckdose (17) in dem ersten Aufnahmeabschnitt (1 a) vorgesehen ist.
EP11186082.1A 2011-10-21 2011-10-21 Laminare Strömungsvorrichtung Not-in-force EP2583752B1 (de)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP11186082.1A EP2583752B1 (de) 2011-10-21 2011-10-21 Laminare Strömungsvorrichtung

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Application Number Priority Date Filing Date Title
EP11186082.1A EP2583752B1 (de) 2011-10-21 2011-10-21 Laminare Strömungsvorrichtung

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EP2583752A1 EP2583752A1 (de) 2013-04-24
EP2583752B1 true EP2583752B1 (de) 2016-11-09

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EP11186082.1A Not-in-force EP2583752B1 (de) 2011-10-21 2011-10-21 Laminare Strömungsvorrichtung

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Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104823711A (zh) * 2015-04-24 2015-08-12 江苏省农业科学院 一种降低食用菌工厂接种污染率的方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DD103959A1 (de) * 1973-05-25 1974-02-12
FR2497826A1 (fr) * 1981-01-12 1982-07-16 Pasteur Institut Hotte pour la manipulation de milieux biologiques, tels que des cultures cellulaires
CH667712A5 (de) * 1985-10-02 1988-10-31 Landis & Gyr Ag Arbeitsstation zur bereitstellung einer stabilisierten lufttemperatur in einer kammer.
US6374621B1 (en) * 2000-08-24 2002-04-23 Cincinnati Sub-Zero Products, Inc. Refrigeration system with a scroll compressor
DE10106349C2 (de) * 2001-02-09 2003-09-18 Kendro Lab Prod Gmbh Verfahren zur Befeuchtung eines Nutzraumes in einem Brutschrank sowie Begasungs-Brutschrank
WO2008128360A1 (de) * 2007-04-20 2008-10-30 Liconic Ag Nutzraum mit fremdkeimunterdrückung

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