EP2555616A4 - Procédé de préparation d'hydrochlorure de mémantine - Google Patents
Procédé de préparation d'hydrochlorure de mémantineInfo
- Publication number
- EP2555616A4 EP2555616A4 EP10849334.7A EP10849334A EP2555616A4 EP 2555616 A4 EP2555616 A4 EP 2555616A4 EP 10849334 A EP10849334 A EP 10849334A EP 2555616 A4 EP2555616 A4 EP 2555616A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- preparation
- memantine hydrochloride
- memantine
- hydrochloride
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/22—Separation; Purification; Stabilisation; Use of additives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C17/00—Preparation of halogenated hydrocarbons
- C07C17/013—Preparation of halogenated hydrocarbons by addition of halogens
- C07C17/06—Preparation of halogenated hydrocarbons by addition of halogens combined with replacement of hydrogen atoms by halogens
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
- C07C209/62—Preparation of compounds containing amino groups bound to a carbon skeleton by cleaving carbon-to-nitrogen, sulfur-to-nitrogen, or phosphorus-to-nitrogen bonds, e.g. hydrolysis of amides, N-dealkylation of amines or quaternary ammonium compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
- C07C209/82—Purification; Separation; Stabilisation; Use of additives
- C07C209/84—Purification
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/10—Preparation of carboxylic acid amides from compounds not provided for in groups C07C231/02 - C07C231/08
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/56—Ring systems containing bridged rings
- C07C2603/58—Ring systems containing bridged rings containing three rings
- C07C2603/70—Ring systems containing bridged rings containing three rings containing only six-membered rings
- C07C2603/74—Adamantanes
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/IN2010/000230 WO2011125062A1 (fr) | 2010-04-08 | 2010-04-08 | Procédé de préparation d'hydrochlorure de mémantine |
Publications (2)
Publication Number | Publication Date |
---|---|
EP2555616A1 EP2555616A1 (fr) | 2013-02-13 |
EP2555616A4 true EP2555616A4 (fr) | 2014-04-02 |
Family
ID=44762075
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP10849334.7A Withdrawn EP2555616A4 (fr) | 2010-04-08 | 2010-04-08 | Procédé de préparation d'hydrochlorure de mémantine |
Country Status (2)
Country | Link |
---|---|
EP (1) | EP2555616A4 (fr) |
WO (1) | WO2011125062A1 (fr) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN106966909B (zh) * | 2016-09-06 | 2019-04-12 | 南京优科制药有限公司 | 一种盐酸美金刚的纯化方法 |
CN110845339A (zh) * | 2019-11-08 | 2020-02-28 | 湖南洞庭药业股份有限公司 | 一种盐酸美金刚的合成方法 |
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3391142A (en) * | 1966-02-09 | 1968-07-02 | Lilly Co Eli | Adamantyl secondary amines |
WO2006076560A1 (fr) * | 2005-01-11 | 2006-07-20 | Teva Pharmaceutical Fine Chemicals S.R.L. | Polymorphes du chlorhydrate de memantine |
WO2006122238A1 (fr) * | 2005-05-11 | 2006-11-16 | Dr. Reddy's Laboratories Ltd. | Procede de preparation de memantine |
US20080033054A1 (en) * | 2006-03-27 | 2008-02-07 | Valeriano Merli | Process for preparing memantine hydrochloride substantially free of impurities |
WO2008040560A1 (fr) * | 2006-10-05 | 2008-04-10 | Krka, D.D., Novo Mesto | Procédé pour la préparation de la mémantine et de sa forme de sel d'acide chlrohydrique |
WO2008062472A2 (fr) * | 2006-10-24 | 2008-05-29 | Cadila Healthcare Limited | Procédé pour la préparation de mémantine |
-
2010
- 2010-04-08 WO PCT/IN2010/000230 patent/WO2011125062A1/fr active Application Filing
- 2010-04-08 EP EP10849334.7A patent/EP2555616A4/fr not_active Withdrawn
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3391142A (en) * | 1966-02-09 | 1968-07-02 | Lilly Co Eli | Adamantyl secondary amines |
WO2006076560A1 (fr) * | 2005-01-11 | 2006-07-20 | Teva Pharmaceutical Fine Chemicals S.R.L. | Polymorphes du chlorhydrate de memantine |
WO2006122238A1 (fr) * | 2005-05-11 | 2006-11-16 | Dr. Reddy's Laboratories Ltd. | Procede de preparation de memantine |
US20080033054A1 (en) * | 2006-03-27 | 2008-02-07 | Valeriano Merli | Process for preparing memantine hydrochloride substantially free of impurities |
WO2008040560A1 (fr) * | 2006-10-05 | 2008-04-10 | Krka, D.D., Novo Mesto | Procédé pour la préparation de la mémantine et de sa forme de sel d'acide chlrohydrique |
WO2008062472A2 (fr) * | 2006-10-24 | 2008-05-29 | Cadila Healthcare Limited | Procédé pour la préparation de mémantine |
Non-Patent Citations (1)
Title |
---|
See also references of WO2011125062A1 * |
Also Published As
Publication number | Publication date |
---|---|
WO2011125062A1 (fr) | 2011-10-13 |
EP2555616A1 (fr) | 2013-02-13 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 20120926 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK SM TR |
|
DAX | Request for extension of the european patent (deleted) | ||
A4 | Supplementary search report drawn up and despatched |
Effective date: 20140228 |
|
RIC1 | Information provided on ipc code assigned before grant |
Ipc: C07C 231/10 20060101ALI20140224BHEP Ipc: C07C 17/06 20060101ALI20140224BHEP Ipc: A01N 33/02 20060101AFI20140224BHEP Ipc: C07C 231/22 20060101ALI20140224BHEP Ipc: C07C 209/84 20060101ALI20140224BHEP Ipc: C07C 209/62 20060101ALI20140224BHEP Ipc: A61K 31/13 20060101ALI20140224BHEP |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20140930 |