EP2542249A4 - Procédés et compositions destinés à favoriser l'intégration de tissu et l'inoculation de cellules stromales adipeuses dans un tissu transplanté et un tissu pénien fabriqué et transplanté - Google Patents

Procédés et compositions destinés à favoriser l'intégration de tissu et l'inoculation de cellules stromales adipeuses dans un tissu transplanté et un tissu pénien fabriqué et transplanté

Info

Publication number
EP2542249A4
EP2542249A4 EP20100847139 EP10847139A EP2542249A4 EP 2542249 A4 EP2542249 A4 EP 2542249A4 EP 20100847139 EP20100847139 EP 20100847139 EP 10847139 A EP10847139 A EP 10847139A EP 2542249 A4 EP2542249 A4 EP 2542249A4
Authority
EP
European Patent Office
Prior art keywords
tissue
transplanted
inosculation
compositions
methods
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
EP20100847139
Other languages
German (de)
English (en)
Other versions
EP2542249A1 (fr
Inventor
Stuart K Williams
Hyun Joon Paek
Erik Vossman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tissue Genesis Inc
Original Assignee
Tissue Genesis Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tissue Genesis Inc filed Critical Tissue Genesis Inc
Priority to EP15164924.1A priority Critical patent/EP2926821B1/fr
Publication of EP2542249A1 publication Critical patent/EP2542249A1/fr
Publication of EP2542249A4 publication Critical patent/EP2542249A4/fr
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/48—Reproductive organs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/33—Fibroblasts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/44—Vessels; Vascular smooth muscle cells; Endothelial cells; Endothelial progenitor cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Cell Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Developmental Biology & Embryology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Zoology (AREA)
  • Virology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Reproductive Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Surgery (AREA)
  • Vascular Medicine (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
EP20100847139 2010-03-05 2010-03-05 Procédés et compositions destinés à favoriser l'intégration de tissu et l'inoculation de cellules stromales adipeuses dans un tissu transplanté et un tissu pénien fabriqué et transplanté Ceased EP2542249A4 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP15164924.1A EP2926821B1 (fr) 2010-03-05 2010-03-05 Compositions permettant de supporter l'intégration de tissus et l'inoculation d'un tissu transplanté et tissu pénien modifié transplanté avec des cellules adipeuses stromales

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2010/026407 WO2011109026A1 (fr) 2010-03-05 2010-03-05 Procédés et compositions destinés à favoriser l'intégration de tissu et l'inoculation de cellules stromales adipeuses dans un tissu transplanté et un tissu pénien fabriqué et transplanté

Related Child Applications (1)

Application Number Title Priority Date Filing Date
EP15164924.1A Division EP2926821B1 (fr) 2010-03-05 2010-03-05 Compositions permettant de supporter l'intégration de tissus et l'inoculation d'un tissu transplanté et tissu pénien modifié transplanté avec des cellules adipeuses stromales

Publications (2)

Publication Number Publication Date
EP2542249A1 EP2542249A1 (fr) 2013-01-09
EP2542249A4 true EP2542249A4 (fr) 2013-08-07

Family

ID=44542472

Family Applications (2)

Application Number Title Priority Date Filing Date
EP15164924.1A Active EP2926821B1 (fr) 2010-03-05 2010-03-05 Compositions permettant de supporter l'intégration de tissus et l'inoculation d'un tissu transplanté et tissu pénien modifié transplanté avec des cellules adipeuses stromales
EP20100847139 Ceased EP2542249A4 (fr) 2010-03-05 2010-03-05 Procédés et compositions destinés à favoriser l'intégration de tissu et l'inoculation de cellules stromales adipeuses dans un tissu transplanté et un tissu pénien fabriqué et transplanté

Family Applications Before (1)

Application Number Title Priority Date Filing Date
EP15164924.1A Active EP2926821B1 (fr) 2010-03-05 2010-03-05 Compositions permettant de supporter l'intégration de tissus et l'inoculation d'un tissu transplanté et tissu pénien modifié transplanté avec des cellules adipeuses stromales

Country Status (2)

Country Link
EP (2) EP2926821B1 (fr)
WO (1) WO2011109026A1 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10751374B2 (en) 2012-01-30 2020-08-25 Michael P. Zahalsky Methods and compositions for treatment of penile defects
US20180028575A1 (en) 2012-01-30 2018-02-01 Michael Zahalsky Methods and compositions for treatment of penile defects
US20150231182A1 (en) * 2012-09-07 2015-08-20 University Of Louisville Research Foundation, Inc. Cell systems and methods for delivering disease-specific therapies
US10588747B2 (en) 2016-10-07 2020-03-17 Coloplast A/S Neophallus implant and a method of implanting a penile prosthetic in a neopenis

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6514292B1 (en) * 1998-05-21 2003-02-04 Children's Medical Center Corporation Corporal tissue penile reconstruction
EP1908820A1 (fr) * 2006-10-06 2008-04-09 Stichting Voor De Technische Wetenschappen Enrichissement de cellules souches et/ou de cellules precurseurs

Family Cites Families (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3949073A (en) 1974-11-18 1976-04-06 The Board Of Trustees Of Leland Stanford Junior University Process for augmenting connective mammalian tissue with in situ polymerizable native collagen solution
US5034506A (en) 1985-03-15 1991-07-23 Anti-Gene Development Group Uncharged morpholino-based polymers having achiral intersubunit linkages
US5235033A (en) 1985-03-15 1993-08-10 Anti-Gene Development Group Alpha-morpholino ribonucleoside derivatives and polymers thereof
US4820626A (en) 1985-06-06 1989-04-11 Thomas Jefferson University Method of treating a synthetic or naturally occuring surface with microvascular endothelial cells, and the treated surface itself
US5035708A (en) 1985-06-06 1991-07-30 Thomas Jefferson University Endothelial cell procurement and deposition kit
US5902741A (en) 1986-04-18 1999-05-11 Advanced Tissue Sciences, Inc. Three-dimensional cartilage cultures
US5266480A (en) 1986-04-18 1993-11-30 Advanced Tissue Sciences, Inc. Three-dimensional skin culture system
US5863531A (en) 1986-04-18 1999-01-26 Advanced Tissue Sciences, Inc. In vitro preparation of tubular tissue structures by stromal cell culture on a three-dimensional framework
US4963489A (en) 1987-04-14 1990-10-16 Marrow-Tech, Inc. Three-dimensional cell and tissue culture system
US5510254A (en) 1986-04-18 1996-04-23 Advanced Tissue Sciences, Inc. Three dimensional cell and tissue culture system
US5041138A (en) 1986-11-20 1991-08-20 Massachusetts Institute Of Technology Neomorphogenesis of cartilage in vivo from cell culture
US4883755A (en) 1987-10-28 1989-11-28 Thomas Jefferson University Method of reendothelializing vascular linings
AU4543193A (en) 1992-06-22 1994-01-24 Henry E. Young Scar inhibitory factor and use thereof
US5672346A (en) 1992-07-27 1997-09-30 Indiana University Foundation Human stem cell compositions and methods
US5957972A (en) 1992-09-29 1999-09-28 Arizona Board Of Regents On Behalf Of The University Of Arizona Implants possessing a surface of endothelial cells genetically-modified to inhibit intimal thickening
DK0671923T3 (da) 1992-10-09 2001-08-13 Advanced Tissue Sciences Inc Leverreserveceller
US5514378A (en) 1993-02-01 1996-05-07 Massachusetts Institute Of Technology Biocompatible polymer membranes and methods of preparation of three dimensional membrane structures
US5709854A (en) 1993-04-30 1998-01-20 Massachusetts Institute Of Technology Tissue formation by injecting a cell-polymeric solution that gels in vivo
US5792603A (en) 1995-04-27 1998-08-11 Advanced Tissue Sciences, Inc. Apparatus and method for sterilizing, seeding, culturing, storing, shipping and testing tissue, synthetic or native, vascular grafts
US6121042A (en) 1995-04-27 2000-09-19 Advanced Tissue Sciences, Inc. Apparatus and method for simulating in vivo conditions while seeding and culturing three-dimensional tissue constructs
WO1996039992A1 (fr) 1995-06-07 1996-12-19 Advanced Tissue Sciences, Inc. Appareil et procede pour steriliser, ensemencer, cultiver, stocker, expedier et tester des tissus cartilagineux de remplacement produits par assemblage
US5842477A (en) 1996-02-21 1998-12-01 Advanced Tissue Sciences, Inc. Method for repairing cartilage
US5763267A (en) 1996-04-16 1998-06-09 Advanced Tissue Sciences Apparatus for the large scale growth and packaging of cell suspensions and three-dimensional tissue cultures
US5827729A (en) 1996-04-23 1998-10-27 Advanced Tissue Sciences Diffusion gradient bioreactor and extracorporeal liver device using a three-dimensional liver tissue
US6224893B1 (en) 1997-04-11 2001-05-01 Massachusetts Institute Of Technology Semi-interpenetrating or interpenetrating polymer networks for drug delivery and tissue engineering
US5786207A (en) 1997-05-28 1998-07-28 University Of Pittsburgh Tissue dissociating system and method
AU729377B2 (en) 1997-10-23 2001-02-01 Asterias Biotherapeutics, Inc. Methods and materials for the growth of primate-derived primordial stem cells in feeder-free culture
US20030082152A1 (en) 1999-03-10 2003-05-01 Hedrick Marc H. Adipose-derived stem cells and lattices
KR100979664B1 (ko) 1999-03-10 2010-09-02 유니버시티 오브 피츠버그 오브 더 커먼웰쓰 시스템 오브 하이어 에듀케이션 지방 유래 간세포 및 격자
AU2001294922A1 (en) 2000-10-02 2002-04-15 Thomas F. Cannon Automated bioculture and bioculture experiments system
US7052829B2 (en) 2001-03-30 2006-05-30 The Arizona Board Of Regents On Behalf Of The University Of Arizona Prevascularized constructs for implantation to provide blood perfusion
WO2002078439A2 (fr) 2001-03-30 2002-10-10 The Arizona Board Of Regents On Behalf Of The University Of Arizona Constructions prevascularisees d'implantation destinees a fournir une perfusion sanguine
WO2007030652A2 (fr) 2005-09-08 2007-03-15 University Of Virginia Patent Foundation Methodes et compositions pour cultiver des cellules souches adipeuses
US8278104B2 (en) 2005-12-13 2012-10-02 Kyoto University Induced pluripotent stem cells produced with Oct3/4, Klf4 and Sox2
US8048999B2 (en) 2005-12-13 2011-11-01 Kyoto University Nuclear reprogramming factor
US20090227032A1 (en) 2005-12-13 2009-09-10 Kyoto University Nuclear reprogramming factor and induced pluripotent stem cells
US20100172883A1 (en) 2007-01-19 2010-07-08 Bruneau Benoit Gaetan Methods of generating cardiomyocytes
US20090304654A1 (en) * 2008-04-30 2009-12-10 Regents Of The University Of California Methods for isolating adipose-derived stem cells and therapeutic use thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6514292B1 (en) * 1998-05-21 2003-02-04 Children's Medical Center Corporation Corporal tissue penile reconstruction
EP1908820A1 (fr) * 2006-10-06 2008-04-09 Stichting Voor De Technische Wetenschappen Enrichissement de cellules souches et/ou de cellules precurseurs

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO2011109026A1 *

Also Published As

Publication number Publication date
WO2011109026A1 (fr) 2011-09-09
EP2926821A1 (fr) 2015-10-07
EP2926821B1 (fr) 2019-12-25
EP2542249A1 (fr) 2013-01-09

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Inventor name: VOSSMAN, ERIK

Inventor name: WILLIAMS, STUART, K.

Inventor name: HOYING, JAMES BEATTY

Inventor name: PAEK, HYUN, JOON

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