EP2533857B1 - Instrument neurologique médical - Google Patents

Instrument neurologique médical Download PDF

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Publication number
EP2533857B1
EP2533857B1 EP11702407.5A EP11702407A EP2533857B1 EP 2533857 B1 EP2533857 B1 EP 2533857B1 EP 11702407 A EP11702407 A EP 11702407A EP 2533857 B1 EP2533857 B1 EP 2533857B1
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EP
European Patent Office
Prior art keywords
instrument according
frequency
medical neurological
medical
energy
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Application number
EP11702407.5A
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German (de)
English (en)
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EP2533857A1 (fr
Inventor
Armando De Vincentiis
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THS Therapeutic Solutions Srl
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THS Therapeutic Solutions Srl
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N5/0613—Apparatus adapted for a specific treatment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36014—External stimulators, e.g. with patch electrodes
    • A61N1/36021—External stimulators, e.g. with patch electrodes for treatment of pain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N2005/0658—Radiation therapy using light characterised by the wavelength of light used
    • A61N2005/0659—Radiation therapy using light characterised by the wavelength of light used infrared
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N2005/0658—Radiation therapy using light characterised by the wavelength of light used
    • A61N2005/0662—Visible light
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N2005/0658—Radiation therapy using light characterised by the wavelength of light used
    • A61N2005/0662—Visible light
    • A61N2005/0663—Coloured light

Definitions

  • the present invention relates to a medical neurological instrument, which is useful in the treatment of some important disorders, and is particularly useful in the systematic improvement of balance, especially to avoid falls of elderly people.
  • Unstable balance related to age is negatively affected by possible pathological conditions and by unfavourably environmental and pharmacological conditions: in some cases even stability perception is impaired.
  • Aizen, E., in Cautious Gait and Fear of Falling in the Elderly Harefuah Nov. 2001, 140 (11): 1091 4-1115 reports that falling often involves a reduction in mobility, due to the fear of falling again. It is therefore apparent that limiting the possibility of falls would result in a great improvement of life conditions and possibly even in a longer life.
  • Posture control concerns all the static-dynamic processes affecting the position of a body in space and the parts of said body in reciprocal motion, maintaining the specific orientation with respect to the force of gravity.
  • the function of the central nervous system is to transform an irregular flow of impulses into a regular activation, which is governed by suitable neuromotor nuclei.
  • proprioceptive sensitivity refers to different kinds of stimuli: contact, pressure, pain. All the information collected through proprioceptors is an essential element for programming and controlling stillness and movement.
  • the most important proprioceptors are neuromuscular spindles and Golgi tendon organs, which are stretch receptors.
  • Spindles are a highly specialised structure, widely distributed in the muscle parenchyma of skeletal muscles. Such a structure consists of a bundle of muscle fibres, enclosed in a capsule. Any muscle stretching is perceived by intrafusal fibres.
  • Neuromuscular spindles are type 1 receptors, responding to energy changes with an electrical potential called "generating potential”.
  • Spindle sensitivity to stretching is very high and is extremely important in the perception of one's position and orientation. A suitable action on proprioceptors is very important to achieve good posture control.
  • the object of the present invention is therefore to provide a device allowing a reduction in the likelihood of falls in the elderly, in a more rapid manner with respect to prior art techniques and without the use of invasive therapies.
  • FIG. 1 For a better understanding of the object described herein, reference will be made to Fig. 1 , in which the following components are schematically indicated:
  • the emitter emits electromagnetic radiation in the form of pulses having a frequency between 0.5 and 500 Hz, preferably between 1 and 200 Hz and these pulses have two alternating discrete frequencies, wherein the first frequency is between 0 and 10 Hz and the second frequency 40 and 1500 Hz.
  • the first frequency is between 0.5 and 5 Hz and the second frequency between 50 and 500 Hz, more preferably the first frequency is between 1 and 3 Hz and the second frequency between 80 and 200 Hz.
  • the first frequency is 3 Hz and the second frequency is 85 Hz, or the first frequency is 2 Hz and the second frequency is 100 Hz, or the first frequency is 1 Hz and the second frequency is 180 Hz.
  • the time T is represented on the abscissa, while the energy supplied e is represented on the ordinate.
  • Teon on time
  • Teoff off time
  • Tp trains of pulses are sent with a variable period and a variable duty cycle for the three energies, determined by the therapy to be performed. It is also possible to send single energy pulses during the pause time Tp.
  • the transducers (18, 19, 20) consist of semiconductive light emitters with fixed emission of 2000 mcd, where these emitters are preferably divided into three groups of at least two units each, so as to repeatedly emit pulses every 2, 4 and 8 sec respectively.
  • the duration of the single pulse is 50-1000 ⁇ s, preferably 80-500 ⁇ s, even more preferably 90-350 ⁇ s.
  • the electromagnetic radiation consists of an electrical current, generated by pairs of electrodes, having a maximum voltage of 240 V, preferably between 50 and 85 V.
  • the strength, frequency and duration of the pulses are controlled from the notebook 8, which, with a specifically developed software program, manages operation thereof.
  • the three energy sources it is essential for the three energy sources to be used simultaneously to obtain a beneficial effect for the patient. These energies are therefore variable according to pathological condition.
  • the present device thus allows the operator to dose the strength, frequency and duration of the pulses for each of the energy sources, obtaining a synergic combination of these sources, which can be optimised for the specific pathological conditions encountered and which can also be customized for each patient.
  • Interface with the Internet 6 also allows interaction and exchange of therapeutic programs, in real time, with the various experiences of the physicians using it, thus allowing the creation of a sort of interactive database in which information on each treatment can be saved, to the benefit of the next operator who wishes to receive information and advice on parameters to use.
  • the aforesaid optimization is therefore shared and can benefit from a plurality of experimental contributions.
  • a preferred configuration comprises six emitters, of which two emitters repeatedly emit pulses every 2 sec., two emitters repeatedly emit pulses every 4 sec. and two emitters repeatedly emit pulses every 8 sec. In other words, the difference in the behaviour of the emitters is found only in the duration of the interval between one pulse and the next.
  • the emitters therefore emit a radiation in the region of the red and infrared wavelength.
  • the useful carrier wavelength is in the interval between 400 and 1,000 nm.
  • the best results are achieved by means of the simultaneous use of a radiation having two discrete wavelengths, the first between 450 and 700 nm and the second between 750 and 1000 nm. In particular, good results are achieved with a first wavelength between 550 and 660 nm and the second wavelength between 850 and 980 nm.
  • the best results are achieved with a first wavelength in the interval between 580 and 645 nm and the second wavelength in the interval between 870 and 920 nm.
  • the radiation can be monochromatic radiation, coherent or incoherent
  • the electromagnetic radiation consists of an electrical current having the same frequency interval.
  • the transducers are electrodes having a negative pole on one side and a positive pole on the other side, to be applied to the skin.
  • the first pair of electrodes generates pulses every 2 sec., the second pair every 4 sec. and the third pair every 8 sec.
  • the current is regulated at a voltage between 0 and 240 V, preferably between 0 and 150 V, more preferably between 0 and 110 V.
  • the length of each pulse is the same as indicated previously.
  • the medical neurological instrument according to the present invention is mainly used to reduce the likelihood of falls in the elderly, without invasive therapies. Alternatively, it can be used to alleviate pain, in particular for myofascial pain, primary and secondary trigger points and referred pain points and in benign chronic pain (secondary algo-dysfunctional syndrome), for example as in the case of osteoarthritic conditions.
  • pulses When used to reduce the likelihood of falls improving balance, pulses must be applied for a time of between 30 sec. and 30 min., preferably between 45 sec. and 10 min., the strength, frequency and duration of the pulses more preferably between 1 min. and 5 min.
  • the pulses are sent every 2 sec., but the instrument is also effective for pulses every 4 sec.
  • the pulses are applied to the patient's limbs. Application improves balance, also during thrust, and the effect lasts for 10 to 40 days, prevalently according to age and condition.
  • the instrument can be useful in pain therapy, in the same conditions, applying it also to the site of the pain for a longer time, usually between 2 min. and 2 hours, preferably between 4 min. and 30 min, more preferably between 5 min. and 15 min. It is particularly useful for alleviating pain in the cervical region, in the lumbar region and for treating osteoarthritis.
  • PATIENT 1 suffering from Alzheimer's and polyarthrosis.
  • the pre/post treatment data are obtained from an average of two trials.
  • PATIENT 2 fibromyalgia, anxiety neurosis.
  • PATIENT 3 osteoporosis, fractures of the vertebrae, severe polyarthrosis, recurring falls
  • PATIENT 5 recurring falls

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biophysics (AREA)
  • Pain & Pain Management (AREA)
  • Pathology (AREA)
  • Electrotherapy Devices (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Radiation-Therapy Devices (AREA)

Claims (12)

  1. Un dispositif médical neurologique consistant en :
    des sources d'énergie, comprenant un émetteur, et
    un système de commande pour gérer lesdites sources d'énergie,
    dans lequel l'émetteur configuré pour appliquer simultanément différents types d'énergie (18, 19, 20) sur un patient comprend des transducteurs dans lesquels les énergies mises en oeuvre sont
    (i) une énergie lumineuse (18) à une longueur d'ondes comprise entre 500 et 700 nm,
    (ii) une énergie lumineuse (19) à une longueur d'ondes comprise entre 701 et 1050 nm,
    (iii) une énergie TENS (20) à une tension maximale de 240 V.
    sur lequel le système de commande est configuré pour régler la puissance, la fréquence et la durée de ces énergies,
    dans lequel l'émetteur est configuré pour émettre un rayonnement électromagnétique sous la forme d'impulsions ayant deux fréquences alternatives discrètes,
    dans lequel la première fréquence atteint 3 Hz et la seconde fréquence atteint 85 Hz, ou la première fréquence atteint 2 Hz et la seconde fréquence atteinte 100 Hz, ou la première fréquence atteint 1 Hz et la seconde fréquence atteint 180 Hz.
  2. Le dispositif médical neurologique selon la revendication 1, caractérisé en ce que les transducteurs (18,19) comprennent des émetteurs de lumière.
  3. Le dispositif médical neurologique selon la revendication 2, dans lequel les émetteurs de lumière sont des émetteurs de lumière à semi-conducteur ayant émission fixe de 2000 mcd.
  4. Le dispositif médical neurologique selon la revendication 3, dans lequel lesdits émetteurs sont disposés en trois groupes d'au moins deux émetteurs par groupe, afin qu'ils émettent de manière répétitive des impulsions respectivement toutes les 2, 4 et 8 secondes.
  5. Le dispositif médical neurologique selon l'une des revendications précédentes, dans lequel chaque impulsion a une durée comprise entre 50 et 1000 µs.
  6. Le dispositif médical neurologique selon la revendication 5, dans lequel chaque impulsion a une durée comprise entre 80 et 500 µs.
  7. Le dispositif médical neurologique selon la revendication 6, dans lequel chaque impulsion a une durée comprise entre 90 et 350 µs.
  8. Le dispositif médical neurologique selon l'une des revendications 1 à 7, caractérisé en ce que le rayonnement électromagnétique consiste en un courant électrique généré par des paires d'électrodes.
  9. Le dispositif médical neurologique selon la revendication 1, dans lequel la tension maximale atteint 200 V, générée par des paires d'électrodes.
  10. Le dispositif médical neurologique selon la revendication 1, dans lequel la tension maximale est comprise entre 50 et 85 V, générée par une paire d'électrodes.
  11. Le dispositif médical neurologique selon l'une des revendications précédentes, dans lequel les impulsions sont caractérisées par :
    un temps de marche (TeON) compris entre 0.01 et 1 ms,
    un temps d'arrêt (TeOFF) compris entre 1 et 10 ms et
    un temps de pause (Tp) compris entre 0.5 et 20 s.
  12. L'instrument selon l'une des revendications précédentes, caractérisé en ce que le système de commande est un ordinateur sur lequel tourne un logiciel dédié.
EP11702407.5A 2010-02-12 2011-01-21 Instrument neurologique médical Active EP2533857B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT000216A ITMI20100216A1 (it) 2010-02-12 2010-02-12 Strumento medico neurologico
PCT/EP2011/050829 WO2011098339A1 (fr) 2010-02-12 2011-01-21 Instrument neurologique médical

Publications (2)

Publication Number Publication Date
EP2533857A1 EP2533857A1 (fr) 2012-12-19
EP2533857B1 true EP2533857B1 (fr) 2014-12-17

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EP11702407.5A Active EP2533857B1 (fr) 2010-02-12 2011-01-21 Instrument neurologique médical

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US (1) US9302117B2 (fr)
EP (1) EP2533857B1 (fr)
JP (1) JP5795005B2 (fr)
CA (1) CA2789268A1 (fr)
ES (1) ES2531444T3 (fr)
IL (1) IL221330A (fr)
IT (1) ITMI20100216A1 (fr)
WO (1) WO2011098339A1 (fr)

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US20120303077A1 (en) 2012-11-29
WO2011098339A1 (fr) 2011-08-18
ITMI20100216A1 (it) 2011-08-13
US9302117B2 (en) 2016-04-05
CA2789268A1 (fr) 2011-08-18
IL221330A0 (en) 2012-10-31
EP2533857A1 (fr) 2012-12-19
JP2013519406A (ja) 2013-05-30
ES2531444T3 (es) 2015-03-16
IL221330A (en) 2016-12-29
JP5795005B2 (ja) 2015-10-14

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