EP2429290A4 - Verbindungen und verfahren zur behandlung von aids und hiv-infektionen - Google Patents

Verbindungen und verfahren zur behandlung von aids und hiv-infektionen

Info

Publication number
EP2429290A4
EP2429290A4 EP10775430A EP10775430A EP2429290A4 EP 2429290 A4 EP2429290 A4 EP 2429290A4 EP 10775430 A EP10775430 A EP 10775430A EP 10775430 A EP10775430 A EP 10775430A EP 2429290 A4 EP2429290 A4 EP 2429290A4
Authority
EP
European Patent Office
Prior art keywords
compounds
methods
hiv infections
treating aids
aids
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP10775430A
Other languages
English (en)
French (fr)
Other versions
EP2429290A1 (de
EP2429290B1 (de
Inventor
Arun K Ghosh
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Purdue Research Foundation
Original Assignee
Purdue Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Purdue Research Foundation filed Critical Purdue Research Foundation
Publication of EP2429290A1 publication Critical patent/EP2429290A1/de
Publication of EP2429290A4 publication Critical patent/EP2429290A4/de
Application granted granted Critical
Publication of EP2429290B1 publication Critical patent/EP2429290B1/de
Not-in-force legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D515/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D515/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D515/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
EP20100775430 2009-05-11 2010-05-11 Verbindungen und verfahren zur behandlung von aids und hiv-infektionen Not-in-force EP2429290B1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US17708609P 2009-05-11 2009-05-11
PCT/US2010/034437 WO2010132494A1 (en) 2009-05-11 2010-05-11 Compounds and methods for treating aids and hiv infections

Publications (3)

Publication Number Publication Date
EP2429290A1 EP2429290A1 (de) 2012-03-21
EP2429290A4 true EP2429290A4 (de) 2012-11-07
EP2429290B1 EP2429290B1 (de) 2014-01-01

Family

ID=43085303

Family Applications (1)

Application Number Title Priority Date Filing Date
EP20100775430 Not-in-force EP2429290B1 (de) 2009-05-11 2010-05-11 Verbindungen und verfahren zur behandlung von aids und hiv-infektionen

Country Status (3)

Country Link
US (2) US8921349B2 (de)
EP (1) EP2429290B1 (de)
WO (1) WO2010132494A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010132494A1 (en) 2009-05-11 2010-11-18 Ghosh Arun K Compounds and methods for treating aids and hiv infections
US8802724B2 (en) 2010-11-30 2014-08-12 Purdue Research Foundation Processes and intermediates for preparing substituted hexahydrofuro [2,3-b] furans
US11230550B2 (en) 2017-06-30 2022-01-25 Purdue Research Foundation Macrocyclic HIV-1 protease inhibitors and uses thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003049746A2 (en) * 2001-12-12 2003-06-19 Tibotec Pharmaceuticals Ltd. Combination of cytochome p450 dependent protease inhibitors

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI9620120A (sl) * 1995-11-14 1999-06-30 Dupont Pharmaceuticals Company Nove makrociklične spojine kot metaloproteazni inhibitorji
AU4828199A (en) * 1998-06-23 2000-01-10 Board Of Trustees Of The University Of Illinois, The Multi-drug resistant retroviral protease inhibitors and associated methods
US7157489B2 (en) * 2002-03-12 2007-01-02 The Board Of Trustees Of The University Of Illinois HIV protease inhibitors
WO2010132494A1 (en) 2009-05-11 2010-11-18 Ghosh Arun K Compounds and methods for treating aids and hiv infections

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003049746A2 (en) * 2001-12-12 2003-06-19 Tibotec Pharmaceuticals Ltd. Combination of cytochome p450 dependent protease inhibitors

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
GHOSH A K ET AL: "Design and synthesis of novel HIV-1 protease inhibitors incorporating oxyindoles as the P2<'>-ligands", BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, PERGAMON, ELSEVIER SCIENCE, GB, vol. 16, no. 7, 1 April 2006 (2006-04-01), pages 1869 - 1873, XP027966355, ISSN: 0960-894X, [retrieved on 20060401] *
See also references of WO2010132494A1 *

Also Published As

Publication number Publication date
US8921349B2 (en) 2014-12-30
WO2010132494A1 (en) 2010-11-18
EP2429290A1 (de) 2012-03-21
EP2429290B1 (de) 2014-01-01
US9617276B2 (en) 2017-04-11
US20150111962A1 (en) 2015-04-23
US20120059161A1 (en) 2012-03-08

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