EP2323557A1 - Système d'imagerie ultrasonore tridimensionnelle - Google Patents

Système d'imagerie ultrasonore tridimensionnelle

Info

Publication number
EP2323557A1
EP2323557A1 EP09792558A EP09792558A EP2323557A1 EP 2323557 A1 EP2323557 A1 EP 2323557A1 EP 09792558 A EP09792558 A EP 09792558A EP 09792558 A EP09792558 A EP 09792558A EP 2323557 A1 EP2323557 A1 EP 2323557A1
Authority
EP
European Patent Office
Prior art keywords
array
beamformer
subarray
beamformers
delay
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP09792558A
Other languages
German (de)
English (en)
Inventor
Alice Chiang
Xingbai He
William Wong
Noah Berger
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
TeraTech Corp
Original Assignee
TeraTech Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US12/286,555 external-priority patent/US8551000B2/en
Application filed by TeraTech Corp filed Critical TeraTech Corp
Publication of EP2323557A1 publication Critical patent/EP2323557A1/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/44—Constructional features of the ultrasonic, sonic or infrasonic diagnostic device
    • A61B8/4444—Constructional features of the ultrasonic, sonic or infrasonic diagnostic device related to the probe
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/44—Constructional features of the ultrasonic, sonic or infrasonic diagnostic device
    • A61B8/4483—Constructional features of the ultrasonic, sonic or infrasonic diagnostic device characterised by features of the ultrasound transducer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/48—Diagnostic techniques
    • A61B8/483—Diagnostic techniques involving the acquisition of a 3D volume of data
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01S—RADIO DIRECTION-FINDING; RADIO NAVIGATION; DETERMINING DISTANCE OR VELOCITY BY USE OF RADIO WAVES; LOCATING OR PRESENCE-DETECTING BY USE OF THE REFLECTION OR RERADIATION OF RADIO WAVES; ANALOGOUS ARRANGEMENTS USING OTHER WAVES
    • G01S15/00—Systems using the reflection or reradiation of acoustic waves, e.g. sonar systems
    • G01S15/88—Sonar systems specially adapted for specific applications
    • G01S15/89—Sonar systems specially adapted for specific applications for mapping or imaging
    • G01S15/8906—Short-range imaging systems; Acoustic microscope systems using pulse-echo techniques
    • G01S15/8909—Short-range imaging systems; Acoustic microscope systems using pulse-echo techniques using a static transducer configuration
    • G01S15/8915—Short-range imaging systems; Acoustic microscope systems using pulse-echo techniques using a static transducer configuration using a transducer array
    • G01S15/8925—Short-range imaging systems; Acoustic microscope systems using pulse-echo techniques using a static transducer configuration using a transducer array the array being a two-dimensional transducer configuration, i.e. matrix or orthogonal linear arrays
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01S—RADIO DIRECTION-FINDING; RADIO NAVIGATION; DETERMINING DISTANCE OR VELOCITY BY USE OF RADIO WAVES; LOCATING OR PRESENCE-DETECTING BY USE OF THE REFLECTION OR RERADIATION OF RADIO WAVES; ANALOGOUS ARRANGEMENTS USING OTHER WAVES
    • G01S15/00—Systems using the reflection or reradiation of acoustic waves, e.g. sonar systems
    • G01S15/88—Sonar systems specially adapted for specific applications
    • G01S15/89—Sonar systems specially adapted for specific applications for mapping or imaging
    • G01S15/8906—Short-range imaging systems; Acoustic microscope systems using pulse-echo techniques
    • G01S15/8909—Short-range imaging systems; Acoustic microscope systems using pulse-echo techniques using a static transducer configuration
    • G01S15/8915—Short-range imaging systems; Acoustic microscope systems using pulse-echo techniques using a static transducer configuration using a transducer array
    • G01S15/8927—Short-range imaging systems; Acoustic microscope systems using pulse-echo techniques using a static transducer configuration using a transducer array using simultaneously or sequentially two or more subarrays or subapertures
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01S—RADIO DIRECTION-FINDING; RADIO NAVIGATION; DETERMINING DISTANCE OR VELOCITY BY USE OF RADIO WAVES; LOCATING OR PRESENCE-DETECTING BY USE OF THE REFLECTION OR RERADIATION OF RADIO WAVES; ANALOGOUS ARRANGEMENTS USING OTHER WAVES
    • G01S7/00—Details of systems according to groups G01S13/00, G01S15/00, G01S17/00
    • G01S7/52—Details of systems according to groups G01S13/00, G01S15/00, G01S17/00 of systems according to group G01S15/00
    • G01S7/52017—Details of systems according to groups G01S13/00, G01S15/00, G01S17/00 of systems according to group G01S15/00 particularly adapted to short-range imaging
    • G01S7/52079—Constructional features
    • G01S7/52082—Constructional features involving a modular construction, e.g. a computer with short range imaging equipment
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01S—RADIO DIRECTION-FINDING; RADIO NAVIGATION; DETERMINING DISTANCE OR VELOCITY BY USE OF RADIO WAVES; LOCATING OR PRESENCE-DETECTING BY USE OF THE REFLECTION OR RERADIATION OF RADIO WAVES; ANALOGOUS ARRANGEMENTS USING OTHER WAVES
    • G01S7/00—Details of systems according to groups G01S13/00, G01S15/00, G01S17/00
    • G01S7/52—Details of systems according to groups G01S13/00, G01S15/00, G01S17/00 of systems according to group G01S15/00
    • G01S7/52017—Details of systems according to groups G01S13/00, G01S15/00, G01S17/00 of systems according to group G01S15/00 particularly adapted to short-range imaging
    • G01S7/52085—Details related to the ultrasound signal acquisition, e.g. scan sequences
    • G01S7/52095—Details related to the ultrasound signal acquisition, e.g. scan sequences using multiline receive beamforming
    • G—PHYSICS
    • G10—MUSICAL INSTRUMENTS; ACOUSTICS
    • G10K—SOUND-PRODUCING DEVICES; METHODS OR DEVICES FOR PROTECTING AGAINST, OR FOR DAMPING, NOISE OR OTHER ACOUSTIC WAVES IN GENERAL; ACOUSTICS NOT OTHERWISE PROVIDED FOR
    • G10K11/00—Methods or devices for transmitting, conducting or directing sound in general; Methods or devices for protecting against, or for damping, noise or other acoustic waves in general
    • G10K11/18—Methods or devices for transmitting, conducting or directing sound
    • G10K11/26—Sound-focusing or directing, e.g. scanning
    • G10K11/34—Sound-focusing or directing, e.g. scanning using electrical steering of transducer arrays, e.g. beam steering
    • G10K11/341—Circuits therefor
    • G10K11/346—Circuits therefor using phase variation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/44—Constructional features of the ultrasonic, sonic or infrasonic diagnostic device
    • A61B8/4444—Constructional features of the ultrasonic, sonic or infrasonic diagnostic device related to the probe
    • A61B8/4472—Wireless probes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01S—RADIO DIRECTION-FINDING; RADIO NAVIGATION; DETERMINING DISTANCE OR VELOCITY BY USE OF RADIO WAVES; LOCATING OR PRESENCE-DETECTING BY USE OF THE REFLECTION OR RERADIATION OF RADIO WAVES; ANALOGOUS ARRANGEMENTS USING OTHER WAVES
    • G01S15/00—Systems using the reflection or reradiation of acoustic waves, e.g. sonar systems
    • G01S15/88—Sonar systems specially adapted for specific applications
    • G01S15/89—Sonar systems specially adapted for specific applications for mapping or imaging
    • G01S15/8906—Short-range imaging systems; Acoustic microscope systems using pulse-echo techniques
    • G01S15/8959—Short-range imaging systems; Acoustic microscope systems using pulse-echo techniques using coded signals for correlation purposes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01S—RADIO DIRECTION-FINDING; RADIO NAVIGATION; DETERMINING DISTANCE OR VELOCITY BY USE OF RADIO WAVES; LOCATING OR PRESENCE-DETECTING BY USE OF THE REFLECTION OR RERADIATION OF RADIO WAVES; ANALOGOUS ARRANGEMENTS USING OTHER WAVES
    • G01S15/00—Systems using the reflection or reradiation of acoustic waves, e.g. sonar systems
    • G01S15/88—Sonar systems specially adapted for specific applications
    • G01S15/89—Sonar systems specially adapted for specific applications for mapping or imaging
    • G01S15/8906—Short-range imaging systems; Acoustic microscope systems using pulse-echo techniques
    • G01S15/8993—Three dimensional imaging systems

Definitions

  • the present invention relates to a system for ultrasound medical imaging that provides three dimensional (3D) imaging using a two dimensional (2D) array of transducer elements in a probe housing.
  • Embodiments of the invention provide systems and methods for medical imaging having high resolution and numerous imaging modalities .
  • the probe housing contains a first beamformmg circuit that transmits beamformed data to a second housing having a second beamformmg circuit.
  • the first beamformmg circuit provides a far-field subarray beamformmg operation.
  • the resulting beamformed data is transmitted from the scan head to a second housing having the second beamformmg circuit that provides near-field beamsteermg and beamfocusmg .
  • a preferred embodiment provides a scan head that can be connected to a conventional ultrasound system in which the scan head provides the inputs to the conventional beamformmg processing function.
  • the scan head beamformer can utilize a low power charge domain processor having at least 32 beamformmg channels.
  • a preferred embodiment of the invention employs a sparse array where only a fraction of the transducer elements need to be activated.
  • the system processor can be programmed to provide the desired sequence for transducer actuation to direct the beam at different angles.
  • a discrete controller can be used to control sparse array actuation.
  • a preferred embodiment provides a scan head with integrated switching circuits for sequentially selecting sparse array actuation elements for sequential multiple beamformmg.
  • the scan head can be connected to a conventional ultrasound system in which the scan head provides the inputs to the conventional beamformmg processing functions.
  • the transmit array elements and receive array elements can be operated independently with the transmit elements comprising a sparse array and the receive elements being a near fully populated array.
  • the multiplexer and beamformer circuits can be integrated into an interface system, or alternatively, into a host processing system, leaving a 2D transducer array mounted in the probe housing.
  • the present invention utilizes nondestructive sensing at each stage of the delay elements in the beamformer. So with a 65 stage delay line, for example, there are 64 usable outputs with one at each stage.
  • the time resolution can be m the range of 1/8 ⁇ to 1/16 ⁇ .
  • a fourth dimension or time resolved image display can be used to record and display a sequence of images recorded at 10 frames per second or higher, for example. This enables viewing of rapidly changing features such as blood or fluid flow; heart wall movement etc. at video frames rates of 30 frames per second.
  • Another preferred embodiment of the invention utilizes a three stage beamformer system in which a first stage performs a first beamformmg operation on data received from a transducer array, which generates first beamformed data that is followed by a second stage that performs a second beamforming operation to provide second stage beamformed data that is then delivered to a third beamforming stage that performs a third beamforming operation .
  • the stages can be performed using charge domain processors. Data can also be converted from analog to digital form before the first stage, or the second stage, at the third stage or thereafter.
  • One stage can utilize parallel beamforming operations and a second stage provides serial beamforming. BRIEF DESCRIPTION OF THE DRAWINGS
  • Fig. 1 illustrates the use of a two dimensional tiled array for ultrasound imaging in accordance with the invention.
  • Fig. 2 illustrates a steerable two dimensional array m accordance with the invention.
  • Fig. 3A illustrates the use of a first beamformer device for far field beamstee ⁇ ng and focusing and a second time delay beamformer for near field beamforming.
  • Fig. 3B illustrates a first analog subarray beamformer forwarding data to a digital beamformer.
  • Fig. 3C illustrates a scanhead for a two dimensional transducer probe.
  • Fig. 3D illustrates a preferred embodiment utilizing a flexible circuit board and cable assembly.
  • Fig. 4 illustrates a preferred embodiment of a three dimensional imaging system in accordance with the integrated Subarray scan head invention.
  • Fig. 5 illustrates a preferred embodiment of the integrated Subarray scan head invention using a charge domain processor for the 2 nd time delay beamforming.
  • Fig. 6A illustrates the use of the integrated subarray scan head probe of the present invention with a second stage beamforming ultrasound processor.
  • Fig. 6B illustrates use of the integrated Subarray scan head with a digital beamformmg processor.
  • Fig. 7 illustrates an ultrasound system in accordance with the invention.
  • Fig. 8A illustrates a sparse array used in accordance with the invention.
  • Fig. 8B graphically illustrates the sparse array performance .
  • Fig. 9A illustrates the use of the integrated sparse array scan head probe of the present invention connected to a host system with charge-domain beamforming processing.
  • Fig. 9B illustrates the use of the integrated sparse array scan head probe of the present invention connected to a conventional digital ultrasound system with m-parallel beamforming components .
  • Fig. 10 illustrates a scan head connected to a portable computer in accordance with a preferred embodiment of the invention.
  • Fig. 11 illustrates a near fully populated receive array m which the receiving elements are independent of, and do not overlap, the transmit array.
  • Fig. 12 graphically illustrates the azimuth and elevation cross-sections of the receive array beampattern.
  • Fig. 13 is a magnified portion of the azimuthal beampattern of Fig. 12 showing the mainlobe and sidelobe structure.
  • Fig. 14 illustrates a near fully populated receive array beampattern .
  • Fig. 15 shows selected transmit locations for a sparse array in accordance with the invention.
  • Fig. 16 illustrates a cross-sectional view of the transmit sparse array beampattern of the embodiment in Fig. 15.
  • Fig. 17 illustrates a sparse transmit array beampattern.
  • Fig. 18 illustrates that it is possible to limit average sidelobe energy to less than -35dB relative to the central peak of the beampattern.
  • Fig. 19 illustrates the 2D differential delay equation.
  • Fig. 20 illustrates a differential display profile.
  • Fig. 21 illustrates differential delay errors.
  • Figs. 22A-22C illustrate embodiments of system processors m a four parallel beamformmg system.
  • Figs. 23A and 23B illustrated non-coded and coded transmit waveforms for spread spectrum ultrasound transmission.
  • Figs. 24A-24C illustrate a process for forming a transmission signal.
  • Figs. 25A-25D illustrate preferred embodiments including a matched filter.
  • the objective of the beamformmg system is to focus signals received from an image point onto a transducer array.
  • signals arriving from the direction of interest are added coherently, while those from other directions do not add coherently or cancel.
  • separate electronic circuitry is necessary for each transducer element.
  • the resulting electronics rapidly become both bulky and costly as the number of elements increases.
  • the cost, size, complexity and power requirements of a high-resolution beamformer have been avoided by "work-around" system approaches.
  • an electronically steerable two-dimensional beamformmg processor based on a delay- and-sum computing algorithm is chosen.
  • the concept of an electronically-adjustable acoustic conformal lens is to divide the surface of a 2D transducer array into plane "tiles" of relatively small subarrays .
  • the tiles/subarrays 120 are made small enough so that when an object is placed within the field-of-view of the imaging system, the incident radiation 122 from the object toward each "tile" can be treated using a far- field approximation.
  • Additional delay elements are incorporated as second-stage processing to allow all subarrays to be coherently summed (i.e., global near-field beamformmg can be achieved by simply delaying and then summing the outputs from all subarrays . )
  • the delay-and-sum beamformer allows each subarray to "look" for signals radiating from a particular direction. By adjusting the delays associated with each element of the array, the array's look direction can be electronically steered toward the source of radiation. Thus instead of looking in one direction as seen at 124a, the direction of tiles 120 can be steered in different direction 124b.
  • the delay line requirement for each element m the sub-array can be less than a hundred stages. Only long delays for global summing are needed for the final near field focusing.
  • a process such as that shown m Fig. 2 can be used.
  • a raster scan 260 can be used to scan an image plane 262 using a 2D steerable transducer array 264.
  • a detailed diagram of an electronically-controlled beamformmg system m accordance with the invention is shown m Fig. 3A.
  • This system consists of a bank of parallel time-delay beamformmg processors 330, -330N.
  • Each processor 330 consists of two components: a 2D sub-array beamformer 332 for far-field beamstee ⁇ ng/focusing and an additional time delay processor 334 to allow hierarchical near-field beamformmg of outputs from each corresponding subarray.
  • the sub-arrays 332 include m-programmable delay lines 340 with tap selectors 342, multiplexers 344 and summed 346 output.
  • n-parallel programmable 2 nd -stage near field time delays are needed for individual delay adjustment which are converted with A/D converter 352 to allow all n-parallel outputs be summed 354 coherently, in turn, this summed output is filtered 338 and provides the 3D images of the targeted object.
  • a processor 336 controls sub-array operation.
  • a plurality of N sub ⁇ array beamformers 400 which can be near-field beamformers in a preferred embodiment, each receive signals from m transducer elements that have separate delay lines whose outputs are summed and provided to beamformers 420 so that this beamformer can be a conventional system with conventional processor 480.
  • a separate sub-array processor 460 controls beamformers 400. Without using this hierarchical subarray far-field and then near-field beamformmg approach, for an 80x80 element 2D array, a cable consisting of six thousand and four hundred wires is needed to connect the transducer array to a conventional beamformmg system. As shown in Fig.
  • the number of inputs to each subarray processor equals the total number of delay elements in the subarray, each sub-array only has a single output.
  • the number of inputs to the subarray bank equals the number of 2D array elements, and the number of outputs from the subarray bank equals to the total transducer array element number divided by the subarray element number, i.e., the number of outputs from the subarray bank reference to the number of inputs is reduced by a factor equal to the size of the subarray.
  • the total number of wires needed to connect to the 2 nd stage near-field beamformmg is reduced by a factor of 25. More specifically, as mentioned above, without using this 2D subarray beamformmg, 6400 wires are needed to connect an 80x80 element 2D transducer array to a conventional back-end beamformmg system. Using a 5x5 subarray processing bank first, the number of wires required to connect to the backend beamformmg system is reduced to 256.
  • a bank of 256 5x5 element subarrays Beamformer can be integrated with a 80x80 element 2D array m the scan head, so a cable consisting of 256 wires is adequate to connect the integrated scan head with the back-end near-field beamformmg system.
  • 5x5 subarray far-field beamformmg processors can be easily integrated in a small size silicon (Si) integrated circuit, eight of such 5x5 subarray beamformers can be integrated on one chip. In this embodiment, only 32 chips or less are integrated into the scan head, thereby reducing the cable size from 6,400 wires down to 256 wires.
  • the beamformer processing system is a time domain processor that can simultaneously process the returns of a large 2D array providing a low-power, highly integrated beamformer system capable of real time processing of the entire array in a portable system. While a system with 192 parallel received channels supports a matrix 2D array probe for a real-time 3D/4D imaging application, the hierarchical multi-stage beamforming can be used with a low-power compact ultrasound system.
  • Fig. 3B demonstrates the hierarchical beamforming architecture in which the beamformmg of a group of neighboring receive elements is implemented m two stages, i.e., instead of a single long delay for each of the receive elements, a common long delay is shared by all elements within the group, but each has its own shorter, programmable delay in front of the long delay. Within each group, the outputs from each of the short delays are summed together then applied to the common long delay.
  • a small group of neighboring receiving elements having this common long delay characteristic is defined as a "subarray" of the transducer array. For example, for application using a 2D matrix array for real-time 3D imaging, the subarray can be a small array with 4x4, or 5x5 adjacent elements.
  • the first stage programmable delays of each element within this subarray are integrated inside the transducer probe; the summed output from each subarray is then connected to the backend processor. So, for a 64x48 element 2D array (3072 or more transducer elements), if a 4x4 subarray is used for the first stage beamformmg, only 192 I/O cable elements are needed to connect the front-probe to the backend processors.
  • the hierarchical beamformmg can also be applied to a one dimensional (ID) array for real-time 2D imaging application.
  • ID one dimensional
  • a group of 8 adjacent elements can be grouped together as a subarray. Within each subarray, each of the 8 elements has its own short programmable delay and then the outputs of the eight delays are summed together and then applied to a common long delay. It is important to note that two different methods that can be used for this two-stage implementation.
  • all the beamformmg circuits including both the short and long delays are placed in the back-end processor, so for a 128 element ID array, 128 connection cables are used as I/O cables between the transducer probe and the backend processor.
  • An alternative implementation is to integrate all the subarray processors within the transducer probe, i.e., for a 128-element array, all 16 subarray processors each with 8 programmable delays are integrated within the transducer probe, so only 16 cable elements are needed to connect the front-end integrated probe with the back-end processors. Within the back- end, only 16 long delay beamformmg circuits are needed to complete the beamformmg function.
  • the back-end processor can be simplified to only 8 beamformmg circuits, only 8 cable elements are needed to connect the front-end integrated probe with the back-end processor.
  • low-power transmit circuit and A/D converters can be integrated into the front-end probe, so a wireless communication can be used to connect the front-end probe and the back-end processor.
  • a wireless USB connection or a wireless FireWire connection can be used.
  • the construction of a 64x48 element 2D transducer probe 485 with integrated 4x4 sub-array processors is illustrated m Fig. 3C.
  • the 64x48element 2D array 487 can include stacking 48 rows of ID arrays each with 64 elements. Connections to the elements of each 64 element ID transducer array are through a flex cable, so the transducer head assembly can include the 2D transducer array and 48 flex cables 486. As shown in Fig.
  • each sub- array can include 4x4 elements (or other rectangular or 2D geometry preferably having at least 16 elements and up to 256 elements per subarray)
  • the 48 flex cables are grouped into 12 groups, with each adjacent four flex cables connected to a printed circuit board, i.e., flex cables corresponding to the row 1 and row 4 ID transducer array are connected to the first printed circuit board 488, the row 5 to row 8 flex cables are connected to the second printed circuit board 487 and so forth, until the row 45 to row 48 flex cables are connected to the twelfth printed circuit board.
  • One end of each flex cables is connected to the transducer elements and the other end of the flex cable is connected to a 64-element flex connector mounted on the printed circuit board.
  • each printed circuit board there are a 16 4x4 element subarray processors 489 and a high voltage multiplexor chip 491.
  • the subarray processor consists of 16 parallel programmable delay lines each with a low-noise pre-amplifier at its input and a separated programmable multiplier as apodizer and the outputs of the 16 multipliers are summed together to form a single outputs.
  • Within each board there is also a high-voltage multiplex chip, so to allow the 4x64 element transducer either operated in transmit or receive mode.
  • a memory chip 490 is also mounted on each printed circuit board to store the programming delay for each of the delay lines.
  • 64 element ID array with integrated first stage subarray processor can also be implemented using the design of Fig. 3C except that a single 64-element transducer array 491 is connected to a flex cable 497 with one end of the flex cable is connected to each of the transducer element, the other end of the cable is connected to a 64-pin flex connector.
  • the connector is mounted on a printed circuit board.
  • Within the printed circuit there are eight 8-element subarray processors.
  • Each subarray processor consists of eight programmable delay lines, each delay line has its separated low-noise pre-amplifer and at the output of the delay line, there is an apodizer, i.e., a multiplier for beamshapmg function.
  • a high-voltage multiplexer circuit chip is also included on the printed circuit board, so to allow the 64 element transducer either operated in transmit or receive mode.
  • a memory chip is also mounted on the printed circuit board to store the programming delay for each of the delay lines. There are also power supply cables and digital inputs connected to each printed circuit boards.
  • FIG. 3D A preferred embodiment of a 64 element (or more, e.g. 128 or 256 elements) ID array 496 with integrated subarray processor is shown in Fig. 3D.
  • the subarray processing chip 499a, the high voltage multiplexer circuit chip 449b and the memory chip 449c are mounted on the flexible printed circuit or cable directly (497, 498) .
  • the systems described herein can be used with a catheter or probe for insertion within body cavities for cardiac imaging (4D) or other internal organs.
  • the probe or catheter assembly can include a circuit housing with the first plurality of beamformers as described herein.
  • FIG. 4 depicts a system that the compact scan head is connected to a dedicated processing module, in which the m- parallel preamp/TGCs 522 transmit/received chips 524 and the 2 nd stage time delay processing units 526 are housed.
  • This dedicated processing module communicates with a host computer 540 via FireWire IEEE 1394 or USB or PCI bus 542.
  • Fig. 5 depicts the same architecture as stated in Fig. 4, except, inside the dedicated processing module, the 2 nd stage time delay processing units are specifically implemented by using charge-domain programmable (CDP) time-delay lines 600 in housing 620 that is connected to handheld probe 660 and computer housing 648.
  • Fig. 6B depicts a system that the compact sparse array scan head 700 is connected to a conventional, commercially available time-domain digital ultrasound imaging system 700 with n-parallel beamforming channels 760. It is easy to see that in Fig. 6A, the time-delay processor 720 can also be implemented by using CDP time-delay lines 740.
  • the near-field beamforming is housed 720, 780 in the same housing with other image processing functions.
  • returned echoes along the line of sight representing the 3D radiation sources can be used to create the scanned image at the scanned angle.
  • the system can provide continuous real-time large area scanned images throughout a large field of view at 20 frames/s or more. At this frame rate, the system can be used to display continuous 3D images vs. time, thus providing 4D information of the scanned object. As shown in Fig.
  • a time multiplexed computing structure can be used to generate multiple beams, i.e., for each transmit pulse, the bank of 2D subarray beamformers 818 and its corresponding 2 nd stage near-field time-delay line are capable of providing multiple beams sequentially.
  • the computing circuits sequentially generate the delays required for forming K beams.
  • the device operates as follows. Once a set of sampled returned-echoes are loaded in the delay lines with sampling circuits 814, at time ti, the delays required for forming beam 1 are computed 812 within each module 822 and applied in parallel to all delay lines. The sampled return-echoes with proper delays are coherently summed 802 and filtered 804 to form the first beam.
  • the delays required for forming beam 2 are computed within each module and applied in parallel to all delay lines.
  • the sampled return-echoes with proper delays are coherently summed to form the second beam.
  • the procedure repeats until the Kth beam is coherently formed.
  • a computing circuit with 16-serial addressable outputs is built in with the CDP subarray and the 2 nd stage time delay lines, for each transmit pulse, 16 beams or scan lines each along a different scan angle can be created.
  • the system can generate a 4096-beams with a 64x64 pixel resolution at a frame rate of 20 frames/s.
  • the system is fully programmable; the beamforming electronics can be adjusted to zoom-in to a smaller field-of-view for high-resolution or higher frame rate images.
  • the system can generate a 3072-beams with a 64x48 pixel resolution at a 30 frame/s frame rate.
  • the array described addresses ultrasound imaging applications using a two-dimensional 2cm x 2cm array at a frequency of 3 MHZ.
  • the need for resolution on the order of less than half the wavelength dictates as large an aperture as possible that can be housed within a compact package.
  • an element pitch or separation of less than 0.25 mm is desirable, leading to a 80x80 element array.
  • a scan head with integrated subarray beamforming circuits followed by a 2 nd stage near-field beamstee ⁇ ng/beamfocusing system provides a practical implementation.
  • the implementation still requires at least 32 subarray chips to be integrated on a scan head.
  • An alternative pseudo random array design approach can be used to achieve this resolution with a much less amount of processing components m the scanned head.
  • the combination of low insertion loss and wide bandwidth performance is important for realizing acceptable imaging performance with low illumination levels.
  • Quarter-wave matching layers with low acoustic impedance, but physically solid backing results m a robust array that loses only 3-4 dB m the conversion of received signal energy to electrical energy.
  • Array band-widths of 75% or more are typical of this design and construction process.
  • the transducer array employs element positioning and an interconnect system suitable for the beamformer circuitry.
  • the electronics are mounted on p ⁇ nted-circuit boards that are attached to the transducer elements via flexible cables. In practice, a majority of the array elements are connected to outputs using the flexible cables. However, only a small fraction of the total number of elements are wired to the circuit boards. Nevertheless, the large number of array element connections are sufficient to insure a unique pattern of active-element locations in the final array.
  • the resulting filling factor is 4%.
  • the output signal to noise ratio of the array is proportional to the number of active elements, so this filling factor corresponds to a loss in sensitivity of -13 dB when compared to a filled array of the same dimensions.
  • a transmitted signal of wider bandwidth is chosen to increase array sensitivity. In the approach presented here, the sensitivity is increased on the order of 10 dB .
  • Positioning the elements of the array follows the approach in which care must be taken to eliminate any periodicity that would produce grating lobes that compete with the main lobe.
  • Pseudorandom or random arrays can be used (FIG. 8A) .
  • the geometry of activated element placement has been developed to maximize the efficiency of the beamformers while minimizing grating and side lobe clutter.
  • Switching between a plurality of different array patterns is used to provide the most efficient beam pattern at different beam angles relative to the region or volume of interest being scanned.
  • a first pattern can utilize that illustrated in Fig. 8A, which is than switched to a second pattern for a different scan angle.
  • the primary goal of the optimization method is to minimize the average side lobe energy. Specifically, this is done by interactively evaluating the optimization criterion:
  • W(u x , u y ) applies more weight to regions in the array response that require side lobe reduction.
  • a random array is capable of producing an imaging point spread function that has a main lobe to average side lobe ratio of N, where N is the total number of active elements m the array.
  • N is the total number of active elements m the array.
  • the resulting ratio is -13 dB .
  • Using a wide bandwidth approach improves this ratio by 10 dB.
  • a pseudorandom placement of the array elements was generated (FIG. 8A) .
  • FIG. 8B is a plot of the array performance, sensitivity versus cross range, for a 256-element sparsely-sampled array at 3 MHZ.
  • the peak to maximum side lobe level is approximately 30 dB.
  • the system is configured to achieve the maximum main lobe to clutter level ratio possible, which has been independently verified.
  • FIG. 9B depicts a system that the sparse array scan head 900 is connected to a conventional, commercially available time-domain digital ultrasound imaging system 940 with m-parallel beamforming channels. It is easy to see that in Fig. 9A, the time-delay processor can also be implemented by using CDP time-delay lines 920 m housing 925 that is connected to a separate computer 927. An array of m multiplexers 906 is used to switch between a sequence of scan patterns executed using a software program and system controller 940 or processor 950. The sequence of sparse array patterns is thus selected to scan at different scan angles of an object being imaged to provide 3D ultrasound imaging thereof .
  • a commercially available window-based 3D visualization software can be used to visualizing, manipulating, and analyzing the 3D multiple-beams volume image data generated by the electronically-adjustable acoustic conformal lens system.
  • a clinician with 2D ultrasound images for diagnosis would look at the 2D scanned images slice by slice and mentally reconstruct the information into a 3D representation to judge the anatomy of the patient.
  • This procedure requires the clinician to have well-founded experience as well as a highly sophisticated understanding of human anatomy.
  • To create a "complete" image to the 3D structures the clinician has to take all available slices into account. Looking at hundreds of slices is too time- consuming, even for a single patient.
  • 3D visualization based on 3D volume data can help overcome this problem by providing the clinician with a 3D representation of the patient's anatomy reconstructed from the set of multiple-scanned beamforming data.
  • a commercially available software tool such as KB-VO13D of KB-VIS technologies, India, provides display or viewing 3D features such as:
  • Shaded-Surface module allows easy visualization of surfaces in the volume. Surfaces may be created by intensity-based thresholding. Alternatively, the Seeding option allows selection of specific connected structures of interest. • MIP (Maximum Intensity Projection) with Radials
  • Volume-interiors are easily visualized using the "Cutaway- Viewing” tool.
  • a Cut-Plane is used to slice through the volume, revealing the interior regions.
  • the cut-plane is easily positioned and oriented using the mouse.
  • the VOI (Volume-of-Interest ) tool allows interactive, real ⁇ time Volume-of-Interest display. The user can isolate and view sub-volumes of interest very easily and in real-time, using easy click-and-drag mouse operation.
  • Images displayed by KB-Vol3D can be captured to various image formats (including DICOM, JPEG, and BMP etc.)
  • Visualization operations can also be captured to an AVI movie .Ie and played on Windows Media Player, QuickTime, and Real Player etc.
  • the invention can be implemented using a scan head 12 connected to a portable computer 14 as shown in Fig. 10.
  • the ultrasound system 10 can also include a cable 16 to connect the probe 12 to the processor housing 14.
  • Certain embodiments can employ an interface unit 13 which can include a beamformer device.
  • Scan head 12 can include a transducer array 15A (2D) and a circuit housing 15B which can house multiplexer and/or beamforming components as described in detail in U.S. Patent Nos . 6,106,472 and 6,869,401, the entire contents of these patents being incorporated herein by reference.
  • a 2D array configuration using sparse-array for transmission and non-overlapped fully-populated array is used for receiving.
  • For an NxM element array only m-elements with optimized sparse array placement are used for transmition and then the remaining NM-m elements are used as the receiving array.
  • This embodiment simplifies the multiplexer requirement needed for a 2D array, in which case the multiplexer can be mounted in the interface housing.
  • FIG. 11 An example of the element locations for the near fully- populated 40 by 60 receive array 50 is shown in Fig. 11.
  • the 2400- element array is depopulated by the 256 sparse array transmit elements to yield 2144 receive element locations. These elements are independent and do not overlap the sparse-array transmit elements.
  • the transmit elements constitute less then 25% of the total number of array elements, and preferably less then 15%.
  • the azimuth and elevation cross-sections of the beampattern of the above mentioned receive array are shown in Fig. 12.
  • the first sidelobe is approximately -13 dB relative to the central peak.
  • the grating lobes are less than -30 dB relative to the peak.
  • the azimuthal beamwidth (plotted in blue (solid) ) is slightly narrower than the elevation beamwidth (plotted in green (dotted) ) .
  • Fig. 13 a magnifying view of the above mentioned azimuthal beam pattern demonstrates the detailed mamlobe and sidelobe structure.
  • the beamwidth is approximately 1.5 degrees.
  • the beam pattern is nearly identical to the fully populated 60x40 element beam pattern.
  • the receive array beam pattern is shown m Fig. 14.
  • the received sparse array is comprised of a 2144 elements. There are no sidelobes due to depopulating the center of the array by 256 (transmit) elements .
  • FIG. 15 An example of the final element locations for the 256 transmit sparse array 60 are shown in Fig. 15.
  • the 256 element locations are confined to the central 32x32 elements of the fully populated array. These elements are independent and do not overlap the receive array elements.
  • a cross sectional view of the transmit sparse array beampattern is shown in Fig. 16.
  • the first sidelobe is approximately -17 dB relative to the central peak.
  • the grating lobes are less than -27 dB relative to the peak.
  • the sparse array optimization algorithm minimizes the sidelobe energy +/- 45 degrees in elevation and +/- 45 degrees in elevation.
  • Fig. 17 demonstrates the beam pattern of the sparse transmit array shown in Fig. 15.
  • the transmit beampattern is designed to uniformly cover a 4x4 beam data pyramid.
  • the transmit sparse array is comprised of a 256-element subset of the fully populated 2400- element array (approximately 10% fill) .
  • the placement of the transmit/receive array design algorithm required over 750 iterations to minimize the transmit and receive sidelobe energy within the +/- 45 degree azimuth, +/- 45 degree elevation region.
  • the final sparse transmit-array element locations limit the average sidelobe energy to less than -35 dB relative to the central peak of the beampattern .
  • a low-power ultrasound system capable of electronically scanning a two-dimensional, 2D, matrix array to generate real ⁇ time three-dimensional, 3D, volumetric images with 64 by 64, 4096, scanning beams at a greater than 20 3D images per second is described.
  • the system is capable of generating 16 received beams.
  • the design is able to drive a one and one-half dimensional array and also support wide-bandwidth encoded transmit waveform for pulse compressing to improve the system sensitivity. Wide bandwidth enables the use of chirped or coded waveforms (PN sequence) that can extend the length of the low power transmit burst without a loss of axial resolution.
  • PN sequence chirped or coded waveforms
  • the beamformer processing system is a time domain processor that will simultaneously process the returns of a large 2D array, the low-power; highly integrated beamformer that provide a real time processing of the entire array and will thus provide a low cost unit that can be hand carried.
  • An example of a system having an electronically-adjustable acoustic conformal lens is to divide the surface of a 2D transducer array into plane "tiles" of relatively small subarrays can be formed m U.S. Patent No. 6,292,433, the contents of which is incorporated herein by reference; beamformmg of the entire array can be separated into two stages, first a small-aperture subarray beamforming followed by a second stage large-aperture coherent summing of the outputs from each of the subarrays.
  • the tiles/subarrays can be made small enough so that when an object is placed within the field-of-view of the imaging system, the incident radiation from the object toward each "tile" can be treated using a far- field approximation.
  • near-field beamforming capability has been incorporated m the actual implementation of the subarray beamformmg system to allow a broader application.
  • Additional delay elements are incorporated as second-stage processing to allow all subarrays to be coherently summed.
  • the delay-and-sum beamformer allows each subarray to "look" for signals radiating from a particular direction. By adjusting the delays associated with each element of the array, the array's look direction can be electronically steered toward the source of radiation.
  • FIG. 6A A detailed diagram of an electronically-controlled beamformmg system m accordance with the invention is shown m Fig 14A of U.S. Patent No. 6,292,433.
  • This system consists of a bank of parallel time-delay beamformmg processors.
  • Each processor consists of two components: a 2D sub-array beamformer for small-aperture beamsteermg/focusmg and an additional time delay processor to allow hierarchical near-field beamformmg of outputs from each corresponding subarray.
  • the number of inputs to each subarray processor equals the total number of delay elements in the subarray, each sub ⁇ array only has a single output. That is to say, the number of inputs to a subarray equals the number of transducer elements associated with that subarray. The number of subarray outputs equals the total transducer array element number divided by the number of subarrays.
  • the total number of wires needed to connect to the 2 nd stage near-field beamformmg is reduced by a factor of 25. More specifically, as mentioned above, without using this 2D subarray beamformmg, 6400 wires are needed to connect an 80x80 2D transducer array to a conventional back-end beamformmg. Using a 5x5 subarray processing bank first, the number of wires required to connect to the backend beamformmg system is reduced to 256.
  • a bank of 256 5x5 element subarrays beamformer can be integrated with a 80x80 element 2D array in the scan head, so a cable consisting of 256 wires is adequate to connect the integrated scan head with the back-end near-field beamformmg system.
  • 5x5 subarray small-aperture beamformmg processors can be easily integrated in a small size silicon integrated circuit, eight of such 5x5 subarray beamformmg can be integrated on one integrated circuit.
  • subarrays have generally between 9 and 64 transducer elements corresponding to a 3x3 subarray up to an 8x8 subarray.
  • the preferred range is at or between 4x4 and a 6x6 array for a square array geometry. Rectangular subarrays can also be used preferably either 3x4, 4x5, or 4x6. Note that a 1/4 ⁇ error minimum criteria is uses. Only 32 integrated circuit devices need be incorporated into the scanhead, it can reduce the cable size from 6,400 wires down to 256 wires. Similarly, for a 64x48 element 2D array, using a 4x4 subarray processing bank in the transducer housing first, the number of back-end beamforming channels is reduced to 192.
  • Figs 4-6B preferred embodiments for a 2D array beamforming, each minimizing noise and cable loss with improved signal to noise ratio performance, are described in Figs 4-6B.
  • the bank of m parallel subarray beamformmg processors are integrated with the 2D transducer array to create a compact, low-noise, scan head.
  • Fig. 4 depicts a system that the compact scan head is connected to a dedicated processing module, in which the m-parallel preamp/TGCs, transmit/received chips and the 2 nd stage time delay processing units are housed.
  • This dedicated processing module communicates with a host computer 540 via FireWire, USB or PCI bus. Control and synchronization is preformed by the system controller located in the processing module.
  • FIG. 5 depicts the same architecture as stated in Fig. 4, except, inside the dedicated processing module, the 2 nd stage time delay processing units are specifically implemented by using Charge-Domain programmable time-delay lines.
  • Figs 6A and 6B depicts a system that the compact scan head is connected to a conventional, commercially available time-domain digital ultrasound imaging system with m-parallel beamformmg channels. It is easy to see that in Figs 6A and 6B the time- delay processor can also be implemented by using CDP time-delay lines .
  • a large-aperture beamformmg system is incorporated into the mam processor housing of the ultrasound imaging system as shown in connection with Figs 19-24B.
  • the speed of sound in tissue is about 1500cm/sec so that the round-trip propagation time for a sound wave penetrating a 15-cm depth is about 20 microseconds.
  • a real-time 3D imaging at least 64x64 scanning beams at a frame rate greater than 20 3D volumetric images per second are needed to provide diagnostic quality images.
  • the real ⁇ time 3D imaging system has to be able to form at least 16 beams for each transmit pulse to support the preferred 3D frame rate requirement.
  • serial and parallel architecture can be used, i.e., the system can use front-end time-multiplexed serial beamformmg elements technique to form two beams, then followed by 8 parallel beamforms at the back-end processor, or the system can form 4 serial beams, for each serial output beam, the back-end processor then forms 4 parallel beams, and so forth.
  • a time multiplexed computing structure can be used to generate multiple beams, i.e., for each transmit pulse, the bank of 2D subarrays and its corresponding 2 nd stage near-field time-delay line are capable of providing multiple beams sequentially.
  • the computing circuits sequentially generate the delays required for forming K beams.
  • the device operates using the following sequence: once a set of sampled returned-echoes are loaded in the delay lines, at time ti, the delays required for forming beam 1 are computed within each module and applied in parallel to all delay lines. The sampled return-echoes with proper delays are coherently summed to form the first beam. At time t 2 , the delays required for forming beam 2 are computed within each module and applied in parallel to all delay lines. The sampled return-echoes with proper delays are coherently summed to form the second beam. The procedure repeats until the Kth beam is coherently formed.
  • a computing circuit with 16-serial addressable outputs is incorporated with the processor subarray and the 2 nd stage time delay lines, for each transmit pulse, 16 beams or scan lines each along a different scan angle can be created.
  • the system can generate a 4096-beams with a 64x64 pixel resolution at a frame rate of 20 frames/s.
  • the system is fully programmable; the beamformmg electronics can be adjusted to zoom-m to a smaller field-of-view for high-resolution or higher frame rate images.
  • the system can generate a 3072-beams with a 64x48 pixel resolution at a 30 frame/s frame rate .
  • the objective of a beamforming system is to focus signals received from an image point onto a transducer array.
  • signals arriving from the direction of interest are added coherently, while those from other directions do not add coherently or cancel.
  • the time-of- flight from the radiation source to the focal point can be calculated and stored in memory for every channel from multiple directions of arrival in parallel.
  • separate electronic circuitry is necessary for each beam; for a multi-beam system, the resulting electronics rapidly become both bulky and costly as the number of beams increases.
  • beamformmg for a linear 192 element array requires 192 parallel delay lines each with a programmable delay length of greater than 128 ⁇ .
  • a total of 768 programmable long delay lines are required.
  • a hierarchical two stage beamformmg system is described.
  • the concept of hierarchical beamformmg is to separate the time-of-flight calculation into two parts: the first part is a short delay for coarse-resolution, small aperture beamformmg, followed by a long delay for fine resolution, large aperture beamformmg.
  • Shown in Fig. 19 is the 3D differential delay equation for a 2D array.
  • This equation represents differential delay at array element (x m , y m ) as a function of range and angles Theta and Phi (relative to the center of the 2D array) .
  • the equation can be reduced to a ID array by setting all of the y m (y coordinates of the element locations) to 0.
  • a differential delay profile must be generated for all elements in the ID or 2D array.
  • the differential delay equation is calculated and all of the differential delays as a function of angles Theta and Phi, at a given range, are tabulated. For example, as shown m Fig. 20, the differential delay profile is plotted for an element near the center of a 2D array.
  • the tabulated data from the preceding step are broken into a coarse delay and a fine delay.
  • the maximum differential delay error is constrained (typically set to have a maximum differential delay error less than or equal to 1 sample) .
  • Fig. 21 depicts the differential delay error as a function of range for a few elements.
  • the maximum differential delay is greater than the constraint (> 1 sample error) ; therefore, the element would not be enabled to receive until a range greater than approximately 100 samples .
  • FIG. 22A A block diagram of an hierarchical two-stage parallel beamforming system 958 is shown in Fig. 22A.
  • a two dimensional transducer array 960 of a handheld probe such as 12 in Fig. 10 weighing less than 15 lbs, can be coupled to amplifier 962 before being connected to the input of the beamforming system 964.
  • the beamforming system can comprise a plurality of short delay lines, which are coherently summed at summing circuit 968 where the output is delivered the longer delay lines 970, which are also summed at summing circuit 972.
  • First stage coarse beamformmg includes coherently summing returned echoes from a small aperture, for example, with 8 neighboring receivers m this particular embodiment.
  • each short delay is only about 8 ⁇ . So, for a 192 element inputs, 24 such small aperture, coarse beams are formed. Each of those 24 beams is then applied to its corresponding long programmable long delay line for a large aperture, fine-resolution beamforming. To form four parallel beams, four such beamformmg structures are required. As can be seen m Fig. 22A, this hierarchical implementation to form 24 coarse beams, only 192 short delays are required, and then followed by 24 long delays, each one with a programmable delay length shorter than 128 ⁇ . For four parallel beams, only 192 short delays plus 96 long delays are needed, it offers a tremendous saving in terms of electronic components and power.
  • a time-of-flight control circuit is used to select the tap position output from a charge-domain processing circuit that non-destructively senses the tapped-delay line output.
  • Each receiver has a multiplier for beam shadmg/apodization .
  • all the multipliers share a common output.
  • the summed charge is then applied to a matched filter to decode and to compress the returned echoes to produce an imaging pulse with a reduced signal-to-noise ration.
  • An analog to digital (A/D) or a converter on-chip charge-domain A/D converter can be used so that hierarchical summing can be carried out digitally.
  • the analog returned echoes received by each transducer element is converted to a digital signal by an analog to digital converter (A/D) during signal processing.
  • A/D converters 976 can be used at the input of each short delay line and the time delays performed digitally.
  • the A/D converters 982 can be used at the output of each coarse beam and the long delay can be performed digitally.
  • the A/D conversion can be performed using available discrete components, or in a preferred embodiment, a charge domain A/D converter can be formed on the same integrated circuit with the charge domain beamformer with hierarchical summing carried out digitally.
  • Fig. 23A Shown in Fig. 23A is an example of a 5 cycle 3 MHz sinusoid without spread spectrum coding.
  • a coded or spread spectrum system transmits a broadband, temporally elongated excitation signal with a finite time-bandwidth product. The received signal is decoded to produce an imaging pulse with improved signal to noise ratio.
  • the benefit of using coded signals in ultrasound imaging systems offers the use of high-resolution imaging while significantly lowering the peak acoustic power. These signals also provide signal processing gain that improves the overall system receiving sensitivity.
  • Direct sequence modulation is the modulation of a carrier by a code sequence. In practice, this signal can be AM (pulse), FM, amplitude, phase or angle modulation. It can also be a pseudorandom or PN sequence that can comprise a sequence of binary values that repeat after a specified period of time.
  • the concept of using spread spectrum/coded excitation transmit waveform comprises modulating a base sequence of transmit pulses of length P with a code sequence with a code length N.
  • a code pulse sequence of N bursts is often referred to as an N-chip code.
  • An example of a gated 3 MHz sinusoid with a 5- Chip Barker coding [111-11] is shown m Fig. 23B.
  • Each "chip" corresponds to 1 cycle of the gated transmit waveform.
  • Fig. 23B appears nearly identical to that of Fig. 23A except that the 4 th cycle is inverted.
  • the continuous line represents the continuously sampled sinusoidal waveform, whereas the cross hatched points is a sampled signal, where 10 samples are taken per cycle.
  • the coded pulse sequence which has a length NxP, can effectively reduce the peak power m the transmitting media by spreading the power spectrum over a longer time duration.
  • a pulse compression matched filter can be used to decode the received signals to produce an imaging pulse that has improved signal to noise ration (SNR) .
  • SNR improvement of a NxP coded pulse sequence is 10 log (NP) . So, for a Barker code of length 7 and a two-cycle burst transmit waveform, a SNR of 11.4dB improvement can be achieved.
  • the transmit and received waveforms are oversampled with an oversampled rate of S.
  • a matched filter with tap length of NxPxS can be used to decode and to compress the returned echoes to produce an imaging pulse with a SNR improvement of lOlog (NPS) .
  • NPS lOlog
  • a SNR of 17.5dB can be achieved.
  • a preferred method of forming a transmission signal is shown in Figs. 24A-24C.
  • the base sequence is a single pulse, as can be seen in Fig. 24A.
  • Fig. 24B represents the convolution of the base sequence with the Barker code.
  • the system transmits an oversampled version of the continuous waveform, as shown in Fig. 24C, a 6-times oversampled waveform is used as transmitted wave from
  • a 192 channel receive beamforming system capable of forming four parallel, compressed beams for each transmitted, spreaded coded excited waveform is shown in the beamformer system 985 of Fig. 25A.
  • a two-stage hierarchical beamformmg architecture is used, first a small aperture short delay beamformer 986 output signals that are coherently summed return echoes from 8 adjacent transducers, a pulse compression matched filter 987 is then followed to decode the received signal, this compressed signal 988 is then applied to a long delay line to complete the beamformmg requirement.
  • an A/D converter 992 is incorporated at each of the matched filter outputs. It follows then the long delay will be carried out digitally, using a second stage digital delay line implementation.
  • the filter 994 consists of a K-stage tapped delay line receiving signals from sampling circuit 995 and K programmable multipliers.
  • the spreaded, coarse beamformed signal, f n is continuously applied to the input of the delay line.
  • g n fn lWi+f n 2 W 2 +f n 3 W 3 +..+f n K 2 W K 2 +fn K lW k l+f n K W K

Abstract

L’invention concerne un système d’imagerie ultrasonore comprenant une tête d’analyse comportant soit un circuit conformateur de faisceau réalisant la conformation de faisceau de sous-réseau en champ lointain, soit un circuit sélecteur de réseau incomplet qui actionne des éléments sélectionnés. Son utilisation conjointe avec un système conformateur de faisceau secondaire permet d’obtenir des images ultrasonores tridimensionnelles.
EP09792558A 2008-09-15 2009-09-15 Système d'imagerie ultrasonore tridimensionnelle Withdrawn EP2323557A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US19206308P 2008-09-15 2008-09-15
US12/286,555 US8551000B2 (en) 2006-06-23 2008-09-30 Ultrasound 3D imaging system
PCT/US2009/056995 WO2010031057A1 (fr) 2008-09-15 2009-09-15 Système d’imagerie ultrasonore tridimensionnelle

Publications (1)

Publication Number Publication Date
EP2323557A1 true EP2323557A1 (fr) 2011-05-25

Family

ID=41226821

Family Applications (1)

Application Number Title Priority Date Filing Date
EP09792558A Withdrawn EP2323557A1 (fr) 2008-09-15 2009-09-15 Système d'imagerie ultrasonore tridimensionnelle

Country Status (4)

Country Link
EP (1) EP2323557A1 (fr)
JP (1) JP5649576B2 (fr)
CN (1) CN102215755A (fr)
WO (1) WO2010031057A1 (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2014003333A (es) * 2011-09-22 2014-04-25 Koninkl Philips Nv Esquemas de excitacion para series de transductores de bajo costo.
GB201216455D0 (en) 2012-09-14 2012-10-31 Isis Innovation Passive ultrasound imaging with sparse transducer arrays
JP6157872B2 (ja) * 2013-02-20 2017-07-05 株式会社東芝 超音波形状計測装置及び計測方法
US11137486B2 (en) 2014-10-08 2021-10-05 Bfly Operations, Inc. Parameter loader for ultrasound probe and related apparatus and methods
CN105463332A (zh) * 2015-12-30 2016-04-06 安徽悦众车身装备有限公司 一种可用于矿用汽车桥壳生产的铸造用钢
JP6819184B2 (ja) * 2016-09-26 2021-01-27 セイコーエプソン株式会社 超音波測定装置および超音波測定装置の制御方法
CN108186052A (zh) * 2017-12-28 2018-06-22 业成科技（成都）有限公司 超声波感测装置
US10718865B2 (en) * 2018-05-14 2020-07-21 Coda Octopus Group Method of compressing beamformed sonar data
FR3086063B1 (fr) * 2018-09-13 2022-11-11 Moduleus Dispositif d'imagerie ultrasonore
JP2022544560A (ja) * 2019-08-13 2022-10-19 ゼッド メディカル，インコーポレイティド マルチセンサカテーテルアセンブリ
CN113768539B (zh) * 2021-09-15 2023-07-14 南京超维景生物科技有限公司 超声三维成像方法和装置、计算机设备、存储介质
EP4220220A1 (fr) * 2022-01-27 2023-08-02 Pulsify Medical Système électronique

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2632846B2 (ja) * 1987-04-30 1997-07-23 ジーイー横河メディカルシステム株式会社 フエーズドアレイソーナ
JP2961903B2 (ja) * 1991-02-07 1999-10-12 株式会社日立製作所 超音波３次元撮像装置
US5685308A (en) * 1994-08-05 1997-11-11 Acuson Corporation Method and apparatus for receive beamformer system
JPH09313487A (ja) * 1996-05-29 1997-12-09 Ge Yokogawa Medical Syst Ltd 超音波３次元像撮像方法および装置
US6530887B1 (en) * 1996-12-24 2003-03-11 Teratech Corporation Ultrasound probe with integrated electronics
US6111816A (en) * 1997-02-03 2000-08-29 Teratech Corporation Multi-dimensional beamforming device
US5938611A (en) * 1998-03-26 1999-08-17 General Electric Company Method and apparatus for color flow imaging using coded excitation with single codes
US6113545A (en) * 1998-04-20 2000-09-05 General Electric Company Ultrasonic beamforming with improved signal-to-noise ratio using orthogonal complementary sets
JP4903928B2 (ja) * 1999-04-23 2012-03-28 ゼネラル・エレクトリック・カンパニイ 符号化励起を用いる三次元フロー・イメージング方法及び装置
KR100350026B1 (ko) * 2000-06-17 2002-08-24 주식회사 메디슨 확산 대역 신호를 이용한 펄스 압축 방식에 기초한 초음파영상 형성 방법 및 장치
US6491634B1 (en) * 2000-10-13 2002-12-10 Koninklijke Philips Electronics N.V. Sub-beamforming apparatus and method for a portable ultrasound imaging system
US6487433B2 (en) * 2001-01-08 2002-11-26 General Electric Company Method and apparatus using golay-coded excitation for echocardiology
US7141020B2 (en) * 2002-02-20 2006-11-28 Koninklijke Philips Electronics N.V. Portable 3D ultrasound system
JP3977827B2 (ja) * 2003-06-25 2007-09-19 アロカ株式会社 超音波診断装置
EP1491913B1 (fr) * 2003-06-25 2006-09-27 Aloka Co. Ltd. Système de diagnostique à imagerie ultrasonore avec transducteur bi-dimensionnel à sous-réseau variable
JP4087762B2 (ja) * 2003-07-24 2008-05-21 アロカ株式会社 超音波診断装置
JP4557575B2 (ja) * 2004-03-25 2010-10-06 株式会社東芝 超音波診断装置
US7635334B2 (en) * 2004-04-28 2009-12-22 Siemens Medical Solutions Usa, Inc. Dynamic sub-array mapping systems and methods for ultrasound imaging
US7914454B2 (en) * 2004-06-25 2011-03-29 Wilk Ultrasound Of Canada, Inc. Real-time 3D ultrasonic imaging apparatus and method
US7874991B2 (en) * 2006-06-23 2011-01-25 Teratech Corporation Ultrasound 3D imaging system
US7687976B2 (en) * 2007-01-31 2010-03-30 General Electric Company Ultrasound imaging system

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See references of WO2010031057A1 *

Also Published As

Publication number Publication date
JP5649576B2 (ja) 2015-01-07
JP2012502692A (ja) 2012-02-02
WO2010031057A1 (fr) 2010-03-18
CN102215755A (zh) 2011-10-12

Similar Documents

Publication Publication Date Title
US11559277B2 (en) Ultrasound 3D imaging system
US8551000B2 (en) Ultrasound 3D imaging system
US10426435B2 (en) Ultrasound 3D imaging system
EP2323557A1 (fr) Système d'imagerie ultrasonore tridimensionnelle
CN101443678B (zh) 具有集成的波束形成的多维cmut阵列
JP2007152127A (ja) 合成開口のための超音波イメージングトランスデューサアレイ
JP2008514335A (ja) マイクロビーム形成を行うトランスデューサの構造
US6730033B2 (en) Two dimensional array and methods for imaging in three dimensions
WO2006000080A2 (fr) Appareil et procede d'imagerie ultrasonore 3d en temps reel
EP2726903B1 (fr) Système d'imagerie de diagnostic ultrasonore bidimensionnel présentant deux étages de formeur de faisceau
JP3977827B2 (ja) 超音波診断装置
US8430819B2 (en) System and method for ultrasound imaging with a configurable receive aperture
US20230346344A1 (en) Ultrasound 3d imaging system
JP3967882B2 (ja) 超音波診断装置
Kim et al. Hybrid beamformation for volumetric ultrasound imaging scanners using 2-D array transducers

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20110315

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK SM TR

AX Request for extension of the european patent

Extension state: AL BA RS

DAX Request for extension of the european patent (deleted)
17Q First examination report despatched

Effective date: 20130604

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20160401