EP2313054A2 - Foaming skincare cream - Google Patents
Foaming skincare creamInfo
- Publication number
- EP2313054A2 EP2313054A2 EP09772048A EP09772048A EP2313054A2 EP 2313054 A2 EP2313054 A2 EP 2313054A2 EP 09772048 A EP09772048 A EP 09772048A EP 09772048 A EP09772048 A EP 09772048A EP 2313054 A2 EP2313054 A2 EP 2313054A2
- Authority
- EP
- European Patent Office
- Prior art keywords
- formulation according
- pharmaceutical
- care
- panthenol
- emulsion
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/04—Dispersions; Emulsions
- A61K8/06—Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/04—Dispersions; Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/04—Dispersions; Emulsions
- A61K8/046—Aerosols; Foams
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/41—Particular ingredients further characterized by their size
- A61K2800/412—Microsized, i.e. having sizes between 0.1 and 100 microns
Definitions
- the invention relates to a foam skin care cream that can be used for wound care as well as for the care, reassurance and prophylactic treatment of stressed skin.
- the use is topical as needed, and is particularly, but not exclusively, indicated in the area of the feet, in the prevention and treatment of mycoses, especially in athlete's foot, and in atopic dermatitis.
- the skin is the functionally most versatile organ of the human organism and requires a correspondingly versatile care. Wound healing itself is a natural biological process.
- the foam skin care cream according to the invention is suitable for wound care in order to prevent complications or infections and delays in wound healing and to optimally shape the cosmetic result of the healing.
- Typical symptoms include dry skin with fissures and rhagades and concomitant symptoms such as inflammation, ulcers etc.
- German patent application 103 40 277 relates to a personal care product with metallic silver.
- Japanese application 1994-62 85 131 discloses a bath additive for the treatment of atopic dermatitis consisting of a porous ceramic
- Carrier material with silver, copper, zinc or one of these combinations is Carrier material with silver, copper, zinc or one of these combinations.
- Japanese application 2002-22 63 83 describes a topical formulation for the treatment of atopic dermatitis containing, inter alia, 0.1 to 10% by weight of an antimicrobial ceramic material of silver, tricalcium phosphate, zinc oxide and silicone dioxides.
- German patent application 103 42 258 relates to an antimicrobial, topical preparation with nanoscale elemental silver in a carrier pasty consistency of ultrafine barium sulfate for the treatment of atopic dermatitis.
- European patent application 1 685 824 relates to a cosmetic formulation for the treatment of inter alia atopic dermatitis which consists of elemental silver, an electrolyte and hydrophobic particles.
- the nature and composition of the silver preparations in the previously mentioned disclosures is different from microsilicone as used in the present invention. This comprises highly porous silver with an average particle size of 10 ⁇ m and a surface area of up to 5 m 2 / g and is available under the name "MicroSilver BG TM" from the company BioEpiderm GmbH in Nuremberg.
- German patent application 10 2005-008299 discloses the use of colloidal, highly porous silver in a cosmetic and / or dermatological formulation for the care, soothing, prophylactic treatment and / or treatment of stressed, chapped, reddened and / or itchy skin to aid one Wound healing, as an antiseptic, for the antimicrobial and / or antifungal treatment of the skin and / or in atopic dermatitis.
- Patent EP 1303283 discloses the use of nanocrystalline silver in a topical formulation for the treatment of hyperproliferative skin diseases.
- German utility model applications 20 2006 014 258.4, 20 2006 004 676.3 and 202 06 983.4 were - as the present application - by Neubourg Skin Care GmbH & CO. KG and describe urea (urea) -containing foam skin care creams and skin care products.
- clotrimazole as a broad-spectrum antifungal has long been known.
- the active ingredient was developed by Bayer AG in the late 1960s. Most forms of preparation are now among the non-prescription drugs and are available as generic from different manufacturers. - A -
- Panthenol also called pantothenol
- Panthenol has long been used to help heal the skin. Panthenol increases the moisture retention capacity of the skin, has nourishing properties and improves the elasticity of the skin. It supports the regeneration of the skin cells and thus contributes to the regeneration of the latter.
- panthenol also has antipruritic and anti-inflammatory properties. Panthenol is used topically and has been known since 1944 under the trade name Bepanthen®.
- Panthenol also called dexpanthenol, D (+) - pantothenyl alcohol or D (+) - pantothenol, is biologically active.
- D-panthenol is preferably used according to the invention, but alternatively L-panthenol or a mixture of different enantiomers may also be used.
- Madecassoside is a concentrated extract of Centella asiatica and has long been known for its effectiveness in wound healing.
- avocado oil is used in the cosmetics and pharmaceutical industries.
- the object of the invention is furthermore to provide a foam cream which is suitable for the prophylaxis and therapy of mycoses, athlete's foot and the like. It is also an object of the invention to provide a foam cream, which is suitable for the prophylaxis and treatment of atopic dermatitis and similar skin diseases.
- Foam formulations have the advantage of being easily distributed on the skin.
- the foamy texture is pleasant and the products usually leave a good skin feeling.
- the physical structure of the foam has a positive effect on the skin protection function.
- Foams are complicated physical structures that require special tuning of the foam-forming components. Foams are generally obtained by spraying an emulsion formulation or an aqueous surfactant (stabilizer) solution
- Foaming formulations according to the invention have a stable two-phase or multi-phase polydisperse structure on application which forms a network structure on the skin comparable to a membrane.
- Such network structures have the advantage that they form a protective function, for example before contact with water, but allow unimpeded gas exchange with the environment. In such foams, there is virtually no obstruction of Perspiratio insensibiles and no corresponding heat accumulation. Thus, the positive properties of a protective and care function are associated with an unchanged skin respiration.
- the foam cream according to the invention contains microsilicone and preferably panthenol. It will be advantageous with one or more pharmaceutical and / or combined with cosmetically active additives. It is characterized by particularly advantageous, previously unknown drug combinations. In particular, hitherto the extremely effective combination of natural substances with conventional active ingredients for wound healing was unknown.
- a preferred embodiment contains microsilver and panthenol natural substances, which are referred to as Madecassoside.
- the wound-healing effects of panthenol and madecassoide complement each other in combination with microsilver to a previously unknown extent.
- the formulation with microsilver additionally allows the antimicrobial and / or antifungal treatment of the skin.
- the highly porous structure of microsilver prevents a toxicologically problematic penetration into deeper skin layers.
- a particularly preferred embodiment in addition to microsilver, panthenol, madecassosides, also contains urea. Urea causes an increase in the
- This embodiment is particularly - but not only - suitable for use in the foot area.
- Madecassoside also evening primrose oil.
- the wound-healing effect of panthenol and madecassoide is complemented with evening primrose oil to a care product, which is particularly - but not only - suitable for the treatment of atopic dermatitis.
- Another preferred embodiment contains microsilver, panthenol, clotrimazole and avocado oil.
- the combination of wound-healing-promoting agents with the antimycotic clotrimazole and microsilver provides a particularly effective formulation for the care of fungus-sensitive skin.
- the said formulation is particularly suitable for the treatment or prevention of athlete's foot.
- Foam creams are aerosols which are formed from an emulsion by means of propellant gas by spraying from a suitable container / dosage form.
- Foam cream formulations therefore generally contain an emulsion and propellant gas.
- Suitable propellants include a propane-butane mixture which causes the pressurized mixture to form foam bubbles.
- the formulation contains 5-15% by weight of propane butane as a propellant gas.
- the propellant is air using an airless dispenser.
- the foam cream according to the invention for use in the foot area is prepared in a suitable, known per se apparatus.
- long-chain esters, alcohols and carboxylic acids described in the prior art and one of the common products against excessive perspiration are preferably used.
- the following recipe belongs to the particularly preferred embodiments of the present invention:
- the remaining percentages by weight are water. From the recipe 85-95 wt .-% are filled with corresponding to 5-15 wt .-% propane-butane as a propellant gas.
Abstract
Description
Claims
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE102008031023A DE102008031023A1 (en) | 2008-06-30 | 2008-06-30 | Foam skin care cream |
PCT/EP2009/003369 WO2010000348A2 (en) | 2008-06-30 | 2009-05-12 | Foaming skincare cream |
Publications (1)
Publication Number | Publication Date |
---|---|
EP2313054A2 true EP2313054A2 (en) | 2011-04-27 |
Family
ID=40935535
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP09772048A Withdrawn EP2313054A2 (en) | 2008-06-30 | 2009-05-12 | Foaming skincare cream |
Country Status (11)
Country | Link |
---|---|
US (1) | US20110097281A1 (en) |
EP (1) | EP2313054A2 (en) |
JP (1) | JP2011526258A (en) |
KR (1) | KR20110040869A (en) |
CN (1) | CN102076314A (en) |
CA (1) | CA2726538A1 (en) |
DE (1) | DE102008031023A1 (en) |
MX (1) | MX2010013983A (en) |
RU (1) | RU2011103256A (en) |
WO (1) | WO2010000348A2 (en) |
ZA (1) | ZA201008693B (en) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE202009016573U1 (en) * | 2009-12-08 | 2010-03-04 | Schermuly, Helmut | Dermal, antimicrobial foot cream |
PL2371350T3 (en) | 2010-03-04 | 2013-09-30 | Neubourg Skin Care Gmbh & Co Kg | Foam formulas for treating animal skin illnesses |
IT1402786B1 (en) * | 2010-11-19 | 2013-09-18 | Fidia Farmaceutici | PHARMACEUTICAL COMPOSITIONS WITH ANTIBACTERIAL AND CICATRIZING ACTIVITIES |
EP2641584A1 (en) * | 2012-03-19 | 2013-09-25 | Coty Germany GmbH | Cosmetic skin composition with soothing effect and its use |
JPWO2014157174A1 (en) * | 2013-03-29 | 2017-02-16 | ホーユー株式会社 | Body composition and anti-malassezia |
FR3025106B1 (en) * | 2014-08-27 | 2017-12-08 | Dermaconcept Jmc | ANTIMICROBIAL COMPOSITION |
US20170000711A1 (en) * | 2015-03-24 | 2017-01-05 | The Procter & Gamble Company | Foam compositions, aerosol products, and methods of using the same to improve sensory benefits to the skin |
US20170000696A1 (en) * | 2015-03-24 | 2017-01-05 | The Procter & Gamble Company | Methods of applying a high dose of a skin care active to skin with improved sensory benefits to the skin |
CN106074264A (en) * | 2016-07-05 | 2016-11-09 | 上海相宜本草化妆品股份有限公司 | A kind of additive and comprise the cosmetics of this additive |
CN107802521A (en) * | 2017-12-04 | 2018-03-16 | 湖南金昌生物技术有限公司 | A kind of leave foam facial treatment milk rich in camellia seed extract and preparation method thereof |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2005023213A1 (en) | 2003-08-29 | 2005-03-17 | Bio-Gate Ag | Body care product containing porous silver particles |
US20080152715A1 (en) * | 2006-12-26 | 2008-06-26 | Seoul National Universtiy Industry Foundation | Method for preparing nanoparticles comprising vitamin K and poly-isopropyl-butyl methacrylate-acrylic acid copolymer with supercritical fluid using molecular association theory |
Family Cites Families (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH06285131A (en) | 1993-04-07 | 1994-10-11 | Asupatsuku Kigyo Kk | Treating material for atopy dermatitis |
WO1997029727A1 (en) | 1996-02-19 | 1997-08-21 | Pierre Giroud | Crutch holder |
US20040161447A1 (en) * | 2000-02-17 | 2004-08-19 | Leonard Paul | Liquid foam producing compositions and dispensing system therefor |
JP2004505057A (en) | 2000-07-27 | 2004-02-19 | ニュクリスト ファーマシューティカルズ コーポレーション | Treatment of hyperproliferative skin disorders and diseases |
JP2002226383A (en) | 2001-01-30 | 2002-08-14 | Masashi Fujii | Skin care preparation having, long-acting antimicrobial spectrum of wide range |
DE20206983U1 (en) | 2002-05-03 | 2002-07-18 | Allpresan Ges Zum Vertrieb Von | sprayer |
US20080206161A1 (en) * | 2002-10-25 | 2008-08-28 | Dov Tamarkin | Quiescent foamable compositions, steroids, kits and uses thereof |
US7820145B2 (en) | 2003-08-04 | 2010-10-26 | Foamix Ltd. | Oleaginous pharmaceutical and cosmetic foam |
US20050186151A1 (en) * | 2003-08-11 | 2005-08-25 | Franck Giroud | Cosmetic composition comprising stabilized and optionally coated metal particles |
FR2858766B1 (en) * | 2003-08-11 | 2005-11-11 | Oreal | COSMETIC COMPOSITION COMPRISING STABILIZED METALLIC PARTICLES, POSSIBLY COATED |
DE10340276B4 (en) | 2003-08-29 | 2006-11-09 | Bio-Gate Bioinnovative Materials Gmbh | Body care with silver and zinc |
DE10342258A1 (en) | 2003-09-11 | 2005-04-07 | Josef Peter Prof. Dr.med. Guggenbichler | Antimicrobial composition for topical application for pharmaceutical or cosmetic purposes comprises elemental silver nanoparticles deposited on an inert support |
EP1727522A2 (en) * | 2004-02-04 | 2006-12-06 | Foamix Ltd. | Cosmetic and pharmaceutical foam with solid matter |
IL166646A0 (en) | 2005-01-30 | 2006-01-15 | Or Le Or Ltd | A new cosmetic composition |
DE102005008299A1 (en) | 2005-02-23 | 2006-12-28 | Icb Investment Consulting Beteiligungen Gmbh | Cosmetic and/or dermatological formulation, useful as e.g. antiseptic, comprises metallic silver as active agent, auxiliary- and basic- materials |
DE202006004676U1 (en) * | 2005-09-28 | 2007-02-08 | Neubourg Skin Care Gmbh & Co. Kg | Formulation, useful as foam skin cream and to treat e.g. dermatitis and psoriasis, comprises an aqueous emulsion, propellant gas, urea emulsion, hyaluronic acid, free fatty acid and at least two emulsions |
JP2009514907A (en) * | 2005-11-09 | 2009-04-09 | バイエル・コンシューマー・ケア・アクチェンゲゼルシャフト | Use of compounds from Centera Asia Chica |
US8858968B2 (en) * | 2005-12-05 | 2014-10-14 | L'oreal | Use of tyrosine-arginine dipeptide and niacinamide as substance P antagonist |
WO2009069006A2 (en) * | 2007-11-30 | 2009-06-04 | Foamix Ltd. | Foam containing benzoyl peroxide |
-
2008
- 2008-06-30 DE DE102008031023A patent/DE102008031023A1/en not_active Withdrawn
-
2009
- 2009-05-12 WO PCT/EP2009/003369 patent/WO2010000348A2/en active Application Filing
- 2009-05-12 MX MX2010013983A patent/MX2010013983A/en not_active Application Discontinuation
- 2009-05-12 CN CN2009801253688A patent/CN102076314A/en active Pending
- 2009-05-12 EP EP09772048A patent/EP2313054A2/en not_active Withdrawn
- 2009-05-12 US US12/737,231 patent/US20110097281A1/en not_active Abandoned
- 2009-05-12 CA CA2726538A patent/CA2726538A1/en not_active Abandoned
- 2009-05-12 KR KR1020117002238A patent/KR20110040869A/en not_active Application Discontinuation
- 2009-05-12 JP JP2011515139A patent/JP2011526258A/en active Pending
- 2009-05-12 RU RU2011103256/15A patent/RU2011103256A/en not_active Application Discontinuation
-
2010
- 2010-12-02 ZA ZA2010/08693A patent/ZA201008693B/en unknown
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2005023213A1 (en) | 2003-08-29 | 2005-03-17 | Bio-Gate Ag | Body care product containing porous silver particles |
US20080152715A1 (en) * | 2006-12-26 | 2008-06-26 | Seoul National Universtiy Industry Foundation | Method for preparing nanoparticles comprising vitamin K and poly-isopropyl-butyl methacrylate-acrylic acid copolymer with supercritical fluid using molecular association theory |
Also Published As
Publication number | Publication date |
---|---|
WO2010000348A8 (en) | 2010-03-11 |
ZA201008693B (en) | 2012-01-25 |
RU2011103256A (en) | 2012-08-10 |
DE102008031023A1 (en) | 2009-12-31 |
WO2010000348A3 (en) | 2010-06-10 |
CA2726538A1 (en) | 2010-01-07 |
KR20110040869A (en) | 2011-04-20 |
JP2011526258A (en) | 2011-10-06 |
US20110097281A1 (en) | 2011-04-28 |
WO2010000348A2 (en) | 2010-01-07 |
MX2010013983A (en) | 2011-01-20 |
CN102076314A (en) | 2011-05-25 |
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