EP2308588A3 - Device and method for mixing a liquid sample - Google Patents

Device and method for mixing a liquid sample Download PDF

Info

Publication number
EP2308588A3
EP2308588A3 EP10009070A EP10009070A EP2308588A3 EP 2308588 A3 EP2308588 A3 EP 2308588A3 EP 10009070 A EP10009070 A EP 10009070A EP 10009070 A EP10009070 A EP 10009070A EP 2308588 A3 EP2308588 A3 EP 2308588A3
Authority
EP
European Patent Office
Prior art keywords
holder
liquid container
mixing
liquid sample
coupling device
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP10009070A
Other languages
German (de)
French (fr)
Other versions
EP2308588A2 (en
EP2308588B1 (en
Inventor
Achim Herz
Thorsten Michels
Holger Dr. Pufahl
Joerg Dr. Schmiedeskamp
Alexander Wiedekind-Klein
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Siemens Healthcare Diagnostics Products GmbH
Siemens Healthcare Diagnostics GmbH Germany
Original Assignee
Siemens Healthcare Diagnostics Products GmbH
Siemens Healthcare Diagnostics GmbH Germany
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Siemens Healthcare Diagnostics Products GmbH, Siemens Healthcare Diagnostics GmbH Germany filed Critical Siemens Healthcare Diagnostics Products GmbH
Publication of EP2308588A2 publication Critical patent/EP2308588A2/en
Publication of EP2308588A3 publication Critical patent/EP2308588A3/en
Application granted granted Critical
Publication of EP2308588B1 publication Critical patent/EP2308588B1/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F31/00Mixers with shaking, oscillating, or vibrating mechanisms
    • B01F31/20Mixing the contents of independent containers, e.g. test tubes
    • B01F31/201Holders therefor
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F31/00Mixers with shaking, oscillating, or vibrating mechanisms
    • B01F31/20Mixing the contents of independent containers, e.g. test tubes
    • B01F31/22Mixing the contents of independent containers, e.g. test tubes with supporting means moving in a horizontal plane, e.g. describing an orbital path for moving the containers about an axis which intersects the receptacle axis at an angle
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F31/00Mixers with shaking, oscillating, or vibrating mechanisms
    • B01F31/20Mixing the contents of independent containers, e.g. test tubes
    • B01F31/24Mixing the contents of independent containers, e.g. test tubes the containers being submitted to a rectilinear movement
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/20Measuring; Control or regulation
    • B01F35/22Control or regulation
    • B01F35/2201Control or regulation characterised by the type of control technique used
    • B01F35/2209Controlling the mixing process as a whole, i.e. involving a complete monitoring and controlling of the mixing process during the whole mixing cycle
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/25Chemistry: analytical and immunological testing including sample preparation

Landscapes

  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Mixers With Rotating Receptacles And Mixers With Vibration Mechanisms (AREA)
  • Accessories For Mixers (AREA)

Abstract

Die vorliegende Erfindung bezieht sich auf eine Vorrichtung und ein Verfahren zum Mischen einer Flüssigkeitsprobe in einem automatischen Analysegerät. Die Vorrichtung umfasst einen Stativarm (11), eine Halterung (12) für einen Flüssigkeitsbehälter, ein flexibles Zwischenelement (13), das zwischen dem Stativarm und der Halterung für den Flüssigkeitsbehälter angeordnet ist, eine Schütteleinrichtung (14) und eine an der Halterung für den Flüssigkeitsbehälter angeordnete Koppeleinrichtung (15), wobei mithilfe der Koppeleinrichtung (15) eine lösbare Verbindung zwischen der Schütteleinrichtung (14) und der Halterung (12) für den Flüssigkeitsbehälter herstellbar ist.

Figure imgaf001
The present invention relates to an apparatus and method for mixing a liquid sample in an automatic analyzer. The device comprises a stand arm (11), a holder (12) for a liquid container, a flexible intermediate element (13), which is arranged between the stand arm and the holder for the liquid container, a shaker (14) and one on the holder for the Liquid container arranged coupling device (15), wherein by means of the coupling device (15) a detachable connection between the shaking device (14) and the holder (12) for the liquid container can be produced.
Figure imgaf001

EP10009070.3A 2009-10-10 2010-09-01 Device for mixing a liquid sample Active EP2308588B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE102009048918A DE102009048918A1 (en) 2009-10-10 2009-10-10 Device for mixing a liquid sample

Publications (3)

Publication Number Publication Date
EP2308588A2 EP2308588A2 (en) 2011-04-13
EP2308588A3 true EP2308588A3 (en) 2012-10-03
EP2308588B1 EP2308588B1 (en) 2015-10-28

Family

ID=43446684

Family Applications (1)

Application Number Title Priority Date Filing Date
EP10009070.3A Active EP2308588B1 (en) 2009-10-10 2010-09-01 Device for mixing a liquid sample

Country Status (5)

Country Link
US (1) US8899821B2 (en)
EP (1) EP2308588B1 (en)
JP (1) JP6016324B2 (en)
DE (1) DE102009048918A1 (en)
ES (1) ES2554173T3 (en)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102009048918A1 (en) * 2009-10-10 2011-04-14 Siemens Healthcare Diagnostics Products Gmbh Device for mixing a liquid sample
FR2987896B1 (en) * 2012-03-08 2014-04-25 Noviloire MEDICAL ANALYSIS AUTOMATE AND CORRESPONDING METHOD
JP6014424B2 (en) * 2012-08-30 2016-10-25 シスメックス株式会社 Stirring device and sample analyzer
EP2705929B1 (en) * 2012-09-06 2021-04-14 Siemens Healthcare Diagnostics Products GmbH Adjustment system for a transfer system in an in-vitro diagnostic system
JP5993679B2 (en) 2012-09-20 2016-09-14 シスメックス株式会社 Sample analyzer
CH709399A1 (en) * 2014-03-20 2015-09-30 Werner Döbelin High-energy mixer for automatic sample preparation in a serial process sequence.
EP3168620A1 (en) 2015-05-28 2017-05-17 Siemens Healthcare Diagnostics Products GmbH Waste shipment system
US10739236B1 (en) 2015-07-08 2020-08-11 BioSpec Products, Inc. Apparatus and method for vortex mixing and cell disruption of a laboratory sample
EP3173794B1 (en) 2015-11-25 2021-07-21 Siemens Healthcare Diagnostics Products GmbH Method for transferring a fluid volume in an analyzer
EP3196649B1 (en) 2016-01-22 2021-08-18 Siemens Healthcare Diagnostics Products GmbH Adjustment system
EP3211423A1 (en) 2016-02-23 2017-08-30 Siemens Healthcare Diagnostics Products GmbH Automatic analyzer with receiving positions for liquid container
EP3216517B1 (en) 2016-03-10 2018-09-12 Siemens Healthcare Diagnostics Products GmbH Method for mixing a liquid in an automatic analyzer
EP3220148B1 (en) 2016-03-17 2020-07-15 Siemens Healthcare Diagnostics Products GmbH Method for monitoring the transport of liquid containers in an automatic analyzer
EP3220147B1 (en) 2016-03-17 2021-09-08 Siemens Healthcare Diagnostics Products GmbH Warning system for potentially faulty measurement results in an automatic analyzer
EP3270166A1 (en) 2016-07-11 2018-01-17 Siemens Healthcare Diagnostics Products GmbH Gripping device for the transport of liquid containers in an automatic analyzer
ES2925941T3 (en) 2017-06-23 2022-10-20 Siemens Healthcare Diagnostics Products Gmbh Optical monitoring of mixing processes
US20200338509A1 (en) * 2017-10-23 2020-10-29 Instrunor As Vibration transfer engagement element, linear actuator and caroussel arrangement
CN107812485B (en) * 2017-11-13 2024-05-03 江西怡杉环保股份有限公司 Stirring device
CN108535083B (en) * 2018-03-29 2020-09-11 滨州医学院附属医院 Blood detection vibrates mixing arrangement with blood
CN109883800B (en) * 2019-02-18 2021-12-24 深圳唯公生物科技有限公司 Sample mixing and moving mechanism and method thereof
EP3699598A1 (en) 2019-02-25 2020-08-26 Siemens Healthcare Diagnostics Products GmbH Waste shipment system
CN112212968B (en) * 2020-09-15 2023-03-17 深圳传世生物医疗有限公司 Vibration detection method and device for mixing cup grabbing hand
GB2610674A (en) * 2022-05-03 2023-03-15 Joseph Edwards Thomas Mixing device, system and method for mixing

Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE517202C (en) * 1928-03-27 1931-02-02 Degussa Shaking device for the production of amalgams, especially for dental purposes
DE816915C (en) * 1949-07-24 1951-10-15 Bayer Ag Device for shaking and stirring
DE1701288U (en) * 1955-04-16 1955-06-23 Werner Dr Franke SHAKING DEVICE FOR LABORATORY PURPOSES.
US3061280A (en) * 1959-04-06 1962-10-30 Kraft Scient Corp Apparatus for mixing fluent material
DE2255707A1 (en) * 1972-11-14 1974-05-30 Inoue Japax Res Dental cement-amalgam prepn. - uses harmonics or photoelectric sensor to stop shaking process automatically
DE2941421A1 (en) * 1979-10-12 1981-04-23 Volkswagenwerk Ag, 3180 Wolfsburg Mixer for flowable materials, esp. paint - which is placed in can subjected to several complex reciprocating motions to agitate the paint
EP0742435A1 (en) * 1995-05-09 1996-11-13 Toa Medical Electronics Co., Ltd. Mixing apparatus
DE19715566A1 (en) * 1997-04-15 1998-10-22 Volker A Fahrney Rotational drive for laboratory equipment
WO2006116892A1 (en) * 2005-05-04 2006-11-09 Tecan Trading Ag Device and method for displacing liquid containers
US20080056059A1 (en) * 2006-09-06 2008-03-06 Henry Troemner, Llc Incubating orbital shaker

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3159384A (en) * 1962-07-02 1964-12-01 Bio Science Labor Agitator for laboratory tubes and flasks
US3346241A (en) * 1966-08-15 1967-10-10 Schubert Auto Body Tools Inc Mixing apparatus
JPS6144223U (en) * 1984-08-28 1986-03-24 セイコーインスツルメンツ株式会社 Mixer for chemical manipulator
JPH01141467U (en) 1988-03-24 1989-09-28
AU618956B2 (en) * 1988-05-09 1992-01-16 Gene-Trak Systems Device for mixing at least one aqueous fluid substance
JP2999084B2 (en) 1993-01-06 2000-01-17 信越化学工業株式会社 Automatic powder product inspection system
FR2679660B1 (en) * 1991-07-22 1993-11-12 Pasteur Diagnostics METHOD AND MAGNETIC DEVICE FOR IMMUNOLOGICAL ANALYSIS ON A SOLID PHASE.
US5947594A (en) * 1998-03-19 1999-09-07 Dolatli; George Agitator device with vibrating clamping member
DE19857215B4 (en) * 1998-12-11 2008-04-10 Dade Behring Marburg Gmbh Multiküvettenrotor
DE102006011370A1 (en) * 2006-03-09 2007-09-20 Eppendorf Ag Device for mixing, in particular, laboratory vessel contents with a sensor
WO2009119918A2 (en) 2008-03-28 2009-10-01 アークレイ株式会社 Fluid agitation method, fluid agitation system, and cartridge
DE102009043524A1 (en) * 2009-09-30 2011-03-31 Siemens Healthcare Diagnostics Products Gmbh Apparatus for the photometric examination of samples
DE102009048918A1 (en) * 2009-10-10 2011-04-14 Siemens Healthcare Diagnostics Products Gmbh Device for mixing a liquid sample

Patent Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE517202C (en) * 1928-03-27 1931-02-02 Degussa Shaking device for the production of amalgams, especially for dental purposes
DE816915C (en) * 1949-07-24 1951-10-15 Bayer Ag Device for shaking and stirring
DE1701288U (en) * 1955-04-16 1955-06-23 Werner Dr Franke SHAKING DEVICE FOR LABORATORY PURPOSES.
US3061280A (en) * 1959-04-06 1962-10-30 Kraft Scient Corp Apparatus for mixing fluent material
DE2255707A1 (en) * 1972-11-14 1974-05-30 Inoue Japax Res Dental cement-amalgam prepn. - uses harmonics or photoelectric sensor to stop shaking process automatically
DE2941421A1 (en) * 1979-10-12 1981-04-23 Volkswagenwerk Ag, 3180 Wolfsburg Mixer for flowable materials, esp. paint - which is placed in can subjected to several complex reciprocating motions to agitate the paint
EP0742435A1 (en) * 1995-05-09 1996-11-13 Toa Medical Electronics Co., Ltd. Mixing apparatus
DE19715566A1 (en) * 1997-04-15 1998-10-22 Volker A Fahrney Rotational drive for laboratory equipment
WO2006116892A1 (en) * 2005-05-04 2006-11-09 Tecan Trading Ag Device and method for displacing liquid containers
US20080056059A1 (en) * 2006-09-06 2008-03-06 Henry Troemner, Llc Incubating orbital shaker

Also Published As

Publication number Publication date
US20110086432A1 (en) 2011-04-14
EP2308588A2 (en) 2011-04-13
EP2308588B1 (en) 2015-10-28
DE102009048918A1 (en) 2011-04-14
JP6016324B2 (en) 2016-10-26
ES2554173T3 (en) 2015-12-16
JP2011078969A (en) 2011-04-21
US8899821B2 (en) 2014-12-02

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