EP2303716B1 - Flasche zur aufnahme von injizierbaren fluiden, insbesondere medizinischen, pharmazeutischen, kosmetischen produkten oder dergleichen - Google Patents

Flasche zur aufnahme von injizierbaren fluiden, insbesondere medizinischen, pharmazeutischen, kosmetischen produkten oder dergleichen Download PDF

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Publication number
EP2303716B1
EP2303716B1 EP20090754181 EP09754181A EP2303716B1 EP 2303716 B1 EP2303716 B1 EP 2303716B1 EP 20090754181 EP20090754181 EP 20090754181 EP 09754181 A EP09754181 A EP 09754181A EP 2303716 B1 EP2303716 B1 EP 2303716B1
Authority
EP
European Patent Office
Prior art keywords
cover
bottle
cap
plug
support means
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Not-in-force
Application number
EP20090754181
Other languages
English (en)
French (fr)
Other versions
EP2303716A1 (de
Inventor
Antonio Fontana
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Lameplast SRL
Original Assignee
Lameplast SRL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lameplast SRL filed Critical Lameplast SRL
Publication of EP2303716A1 publication Critical patent/EP2303716A1/de
Application granted granted Critical
Publication of EP2303716B1 publication Critical patent/EP2303716B1/de
Not-in-force legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D51/00—Closures not otherwise provided for
    • B65D51/002—Closures to be pierced by an extracting-device for the contents and fixed on the container by separate retaining means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/18—Arrangements for indicating condition of container contents, e.g. sterile condition
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D51/00—Closures not otherwise provided for
    • B65D51/18—Arrangements of closures with protective outer cap-like covers or of two or more co-operating closures
    • B65D51/20—Caps, lids, or covers co-operating with an inner closure arranged to be opened by piercing, cutting, or tearing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/1468—Containers characterised by specific material properties
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D2251/00—Details relating to container closures
    • B65D2251/0003—Two or more closures
    • B65D2251/0006—Upper closure
    • B65D2251/0025—Upper closure of the 47-type
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D2251/00—Details relating to container closures
    • B65D2251/0003—Two or more closures
    • B65D2251/0068—Lower closure
    • B65D2251/009—Lower closure of the 51-type

Definitions

  • the present invention relates to a bottle for containing injectable fluids, particularly medical, pharmaceutical, cosmetic products or the like.
  • sterile fluids are normally supplied in bottles made of glass or plastic, which are chemically inert materials and suitable for safeguarding the sterility of the fluids which they contain.
  • the bottles are usually closed by means of a closing element called “stopper”, which is fitted in the access mouth of the bottle.
  • the closing element is made of rubber to allow its penetration by a pointed extraction element, such as e.g. the needles of hypodermic syringes and infusion line spikes, and thus allow the extraction and exit of the sterile fluid. Furthermore, for the purpose of preventing the portion of the stopper intended for penetration being contaminated with polluting substances and dirt, this is generally covered with a protection cap that can be screwed around the bottle neck.
  • a pointed extraction element such as e.g. the needles of hypodermic syringes and infusion line spikes
  • the cap comprises a tear-off removable portion, that can be removed to gain access to the stopper from the outside.
  • the removable portion has a grip eyelet, a tab or other similar systems that permit gripping the removable portion and tearing it fully away from the rest of the protection cap, which remains stably fastened to the bottle neck.
  • Bottles of this type are described in EP 0 819 617 and EP 1 044 135 .
  • a bottle comprising all the technical features of the preamble of claim 1 is known from US 5 405 031 .
  • the tear-away removal of the removable portion of the cap means splitting the cap into two distinct pieces, which therefore need to be disposed of at different times and in different ways.
  • the removable portion in fact must be thrown away once removed, i.e., when the bottle is opened and at the start of its use; the rest of the bottle, on the other hand, becomes a waste to be thrown away only once it has been emptied of its contents, i.e., after it has been used.
  • the main aim of the present invention is to provide a bottle for containing injectable fluids, particularly medical, pharmaceutical, cosmetic products or the like, that is practical, easy and functional to use, can be opened quickly using just one hand, freeing the user from the need of having to use both hands, and at the same time permits considerably reducing waste materials, facilitating waste disposal operations.
  • Another object of the present invention is to provide a bottle for containing injectable fluids, particularly medical, pharmaceutical, cosmetic products or the like, that allows overcoming the mentioned drawbacks of the background art in the ambit of a simple, rational, easy, effective to use and low cost solution.
  • the present bottle for containing injectable fluids comprising at least a container for containing an injectable fluid having at least an access mouth, at least a closing element that is at least partially inserted in said access mouth and which has at least an area in penetrable material suitable for being crossed by an extracting element for extracting said injectable fluid, and at least a protection plug for protecting said closing element, characterized in that said plug comprises at least a cap that can be placed to at least partially cover said closing element and which has at least an opening for accessing said area, and at least a cover that is associated with said cap by interposition of rotation means around a swinging axis and which supports at least a shutter element that can be fitted sealed in said opening , said plug comprising second anti-tampering seal means interposed between said cover and said shutter of said plug.
  • the bottle 1 comprises a container 2 for containing an injectable fluid 3 to be administered to a patient by means of a syringe, an infusion line or the like.
  • the container 2 has a bottom 4, at which is associable a hanger 5, and a threaded neck 6, which is arranged in the opposite direction to the bottom 4 and which terminates with an access mouth 7.
  • a closing element 8 of the type of a rubber stopper is at least in part insertable by interlock.
  • the closing element 8 has a thinned area 9, in penetrable material, which is suitable for being crossed by an extraction element for the extraction and the exit of the injectable fluid 3.
  • the extraction element is not shown in detail in the illustrations and, e.g., consists of a syringe needle, an infusion line spike or similar devices.
  • At the top of the collar 6 is associable a plug 10 for the protection of the closing element 8.
  • Both the container 2 and the plug 10 are advantageously made of plastic, e.g., in polypropylene.
  • the plug 10 in particular, comprises a cap 11 that is placeable to cover the closing element 8 and which has an opening 12 for accessing the area 9.
  • the cap 11 has a substantially round section cylindrical shape and is composed, e.g., of a cylindrical side body 13, inside which is obtained an inner thread 14 engageable by screwing on the neck 6 of the container 2, and of an annular wall 15, which is associated at the top of the cylindrical side body 13.
  • the opening 12 is obtained on the annular wall 15 in such a position that, when the cap 11 is fitted on the neck 6, the opening 12 is arranged at the area 9. Furthermore, the plug 10 comprises a cover 16 that is associated with the cap 11 by interposition of the rotation means 17 around a swinging axis.
  • the rotation means 17 are arranged on the periphery of the cap 11, i.e., on the edge of the annular wall 15, and tangent with this, and are composed of a first folding line with weakened section.
  • the cap 11 and the cover 16 are made in a single body by means of injection moulding and remain joined together at the first folding line 17, the weakened section of which permits turning the cap 11 and the cover 16, the one with respect to the other, between a closing configuration, in which the cover 16 is up against the annular wall 15, and an opening configuration, in which on the other hand the cover 16 is turned with respect to the annular wall 15.
  • the cover 16 supports a shutter element 18 which in the closing configuration of the plug 10 can be fitted sealed in the opening 12.
  • the shutter element 18 is defined by a cylindrical body with shape substantially complementary to that of the opening 12.
  • first anti-tampering seal means 19, 20, 21 suitable for evidencing whether or not the plug 10 has been previously opened.
  • the first anti-tampering seal means 19, 20, 21 consist, e.g., of a protruding element 19, of the type of a tooth or the like, that is associated with the cover 16 by interposition of first tearable support means 20, and of a retention seat 21, that is obtained on the cap 11 and in which the protruding element 19 can be slotted in the closing configuration of the plug 10.
  • the tooth 19 is defined on a flap 22 that is arranged on the diametrically opposite side of the cover 16 with respect to the first folding line 17 and which is associated with the rest of the cover 16 along a second folding line 23 with weakened section, substantially parallel with the first folding line 17, that enables the flap 22 to fold with respect to the rest of the cover 16.
  • a through slot 24 on the inner edge of which are arranged the first tearable support means 20 made up, e.g., of a series of preset fracture connecting bridges suitable for breaking once the tooth 19 is fitted in the retention seat 21.
  • the retention seat 21 is obtained on the annular wall 15 of the cap 11 on the diametrically opposite side with respect to the first folding line 17 so that in closing configuration of the plug 10 the tooth 19 fits exactly in the retention seat 21.
  • the plug 10 comprises second anti-tampering seal means 25, 26 placed between the cover 16 and the shutter element 18.
  • the shutter element 18 is associated with the cover 16 by means of the second anti-tampering seal means 25, 26.
  • second anti-tampering seal means comprise second tearable support means 25, of the type of a series of preset fracture connecting bridges, and a supporting edge 26 suitable for keeping the cover 16 and the shutter element 18 joined together upon breakage of the second tearable support means 25.
  • the supporting edge 26, in detail, is obtained on the cover 16 on the part arranged at and near the first folding line 17.
  • This arrangement of the supporting edge 26, together with the particular sizing of the section of the second tearable support means 25, causes, when the cover 16 is opened starting from the closing configuration, the shutter element 18 to remain temporarily blocked inside the opening 12 so as to allow the breakage of the second tearable support means 25 while, once out of the opening 12, the shutter element 18 remains attached to the cover 16 by means of the supporting edge 26.
  • third anti-tampering seal means 27, 28, 29 placed between the cap 11 and the container 2 are third anti-tampering seal means 27, 28, 29.
  • the third anti-tampering seal means 27, 28, 29 comprise a seal ring 27 which is associated with the base of the cap 11 by interposition of third tearable support means 28 and can be coupled by slotting in with a retention edge 29 obtained on the neck 6 of the container 2.
  • the seal ring 27 is obtained in a single body with the cap 11 and the third tearable support means 28 are composed of a series of preset fracture connecting bridges.
  • the seal ring 27 and the retention edge 29 are shaped so the cap 11 can be fitted on the neck 6 without causing the breakage of the third tearable support means 28 while, on the contrary, when we try to unscrew the plug 10, the retention edge 29 opposes resistance to the moving away of the seal ring 27 determining the fracture of the third tearable support means 28.
  • the plug 10 is arranged in an initial opening configuration ( figure 3 ) in which the first, the second and the third tearable support means 20, 25 and 28 are integral, the tooth 19 is fitted on the flap 22, the shutter element 18 is fitted on the cover 16 and the seal ring 27 is fitted on the base of the cap 11.
  • the user levers on the flap 22 and pushes the cover 16 to turn around the first folding line 17 placing the plug in the final opening configuration shown in the figure 4 .
  • Such operation is particularly simple and can also be performed by the user with just one hand, enabling him/her to keep the other hand free or use it to grip the extraction element and prepare it for its subsequent fitting in the closing element 8.
  • the bottle 1 has a container 2 that is completely identical to that of the previous embodiment; consequently, in these illustrations, the container 2 has not been shown, but only the plug 10.
  • the plug 10 of this embodiment is altogether similar to that shown in the figures from 1 to 4 and comprises a cap 11, a cover 16, a shutter element 18, first anti-tampering seal means 19, 20, 21 and third anti-tampering seal means 27, 28, 29 identical to those previously described and which, therefore, will not be the subject of further detailed explanation, it remaining understood that for these reference is best made to the above description.
  • the shutter element 18 is integrally and rigidly joined to the cover 16 and to prove that the cover 16 has been opened remains the tooth 19 slotted into the retention seat 21. It has in point of fact been ascertained how the described invention achieves the proposed objects.
  • the bottle according to the invention can be opened in a practical, easy and functional way, and above all quickly and using just one hand, thus allowing the user to prepare the other hand for inserting a needle, a spike or the like in the rubber closing element.

Landscapes

  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Closures For Containers (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)

Claims (15)

  1. Flasche (1) zur Aufnahme von injizierbaren Fluiden, insbesondere medizinischen, pharmazeutischen, kosmetischen Produkten oder dergleichen, mit:
    mindestens einem Behälter (2) zur Aufnahme eines injizierbaren Fluids (3), der mindestens eine zugangsöffnung (7) besitzt,
    mindestens einem Verschlusselement (8), das mindestens teilweise in die Zugangsöffnung (7) eingeschoben ist, und das mindestens einen Bereich aus durchlässigem Material besitzt, durch den ein Abzugselement hindurchgehen kann, um das injizierbare Fluid abzuziehen, und
    mindestens ein Schutzstopfen (10) zum Schutz des Verschlusselementes (8), der seinerseits folgendes aufweist:
    mindestens eine Kappe (11), die derart angebracht werden kann, dass sie das Verschlusselement (8) zumindest teilweise abdeckt, und die mindestens eine Öffnung (12) für den Zugang zu dem Bereich (9) besitzt, und
    mindestens eine Abdeckung (16), die mit der Kappe (11) durch Einfügen von Drehelementen (17) um eine Drehachse herum verbunden ist, und die mindestens ein Schließelement (18) hält, das in der Öffnung (12) dicht verschlossen angebracht werden kann, wobei die Flasche (1) dadurch gekennzeichnet ist, dass
    der Stopfen (10) zweite manipulationssichere bzw. entnahmesichere Abdichtelemente (25, 26) besitzt, die zwischen der Abdeckung (16) und dem Schließelement (18) des Stopfens (10) eingeschoben sind.
  2. Flasche (1) nach Anspruch 1, dadurch gekennzeichnet, dass die Drehelemente (17) im Wesentlichen am äußeren Umfang der Kappe (11) angeordnet sind.
  3. Flasche (1) nach einem oder mehreren der vorhergehenden Ansprüche, dadurch gekennzeichnet, dass die Drehelemente mindestens eine erste Falzlinie (17) mit abgeschwächtem Abschnitt bzw. Sollbruchstelle aufweisen.
  4. Flasche (1) nach einem mehreren der vorhergehenden Ansprüche, dadurch gekennzeichnet, dass das Schließelement (18) mindestens einen Hauptteil mit einer Form in Ergänzung zu der Öffnung (12) besitzt.
  5. Flasche nach einem oder mehreren der vorhergehenden Ansprüche, dadurch gekennzeichnet, dass der Stopfen (10) weiterhin erste manipulationssichere bzw. entnahmesichere Abdichtelemente (19, 20, 21) besitzt, die zwischen der Abdeckung (16) und der Kappe (11) eingeschoben sind, und die mindestens ein vorstehendes Element (19) aufweisen, das durch Einfügen erster zerreißbarer Halteelemente (20) mit einer Abdeckung (16) und einer Kappe (11) verbunden ist, und mindestens einen Haltesitz (21), der sich an der anderen Kappe (11) und an der anderen Abdeckung (16) befindet, und in den das vorstehende Element (19) eingesteckt werden kann.
  6. Flasche nach Anspruch 5, dadurch gekennzeichnet, dass das vorstehende Element (19) mit einer Klappe (22) der Abdeckung (16) verbunden ist.
  7. Flasche nach Anspruch 6, dadurch gekennzeichnet, dass die Klappe (22) mit dem Rest der Abdeckung (16) entlang einer Falzlinie (23) mit abgeschwächtem Abschnitt bzw. Sollbruchstelle verbunden ist.
  8. Flasche nach einem oder mehreren der vorhergehenden Ansprüche 5 bis 7, dadurch gekennzeichnet, dass die ersten zerreißbaren Halteelemente (20) mindestens eine Verbindungsbrücke mit Sollbruchstelle aufweisen.
  9. Flasche nach einem oder mehreren der vorhergehenden Ansprüche, dadurch gekennzeichnet, dass die zweiten manipulationssicheren bzw. entnahmesicheren Abdichtelemente (25, 26) zweite zerreißbare Halteelemente (25) aufweisen, die zwischen der Abdeckung (16) und dem Schließelement (18) eingeschoben sind.
  10. Flasche nach Anspruch 9, dadurch gekennzeichnet, dass die zweiten zerreißbaren Halteelemente (25) mindestens eine Verbindungsbrücke mit Sollbruchstelle aufweisen.
  11. Flasche nach Anspruch 9 oder 10, dadurch gekennzeichnet, dass die zweiten manipulationssicheren bzw. entnahmesicheren Abdichtelemente (25, 26) mindestens einen Auflagerand (26) besitzen, der zwischen der Abdeckung (16) und dem Schließelement (18) eingeschoben ist, und der geeignet ist, die Abdeckung (16) und das Schließelement (18) beim Aufbrechen des zweiten zerreißbare Halteelementes (25) zusammenzuhalten.
  12. Flasche (1) nach einem oder mehreren der vorhergehenden Ansprüche, dadurch gekennzeichnet, dass die Kappe (11) mindestens ein Innengewinde (14) aufweist, das durch Aufschrauben auf den Behälter (2) an der Zugangsöffnung (7) in Eingriff gebracht werden kann.
  13. Flasche nach einem oder mehreren der vorhergehenden Ansprüche, dadurch gekennzeichnet, dass sie dritte manipulationssichere bzw. entnahmesichere Abdichtelemente (27, 28, 29) besitzt, die zwischen der Kappe (11) und dem Behälter (2) eingeschoben sind, und mindestens einen Dichtungsring (27) besitzen, der durch Einschieben eines dritten manipulationssicheren bzw. entnahmesicheren Abdichtelementes (28) mit der Basis der Kappe (11) verbunden ist, und durch Einstecken in eine Haltekante (29) an dem Behälter (2) koppelbar ist.
  14. Flasche nach Anspruch 13, dadurch gekennzeichnet, dass das dritte manipulationssichere bzw. entnahmesichere Abdichtelement (28) mindestens eine Verbindungsbrücke mit Sollbruchstelle besitzt.
  15. Flasche nach einem oder mehreren der vorhergehenden Ansprüche, dadurch gekennzeichnet, dass das Schließelement (18) und die Abdeckung (16) starr und stabil miteinander verbunden sind.
EP20090754181 2008-05-27 2009-05-18 Flasche zur aufnahme von injizierbaren fluiden, insbesondere medizinischen, pharmazeutischen, kosmetischen produkten oder dergleichen Not-in-force EP2303716B1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT000160A ITMO20080160A1 (it) 2008-05-27 2008-05-27 Flacone per il contenimento di fluidi iniettabili, particolarmente prodotti medicali, farmaceutici, cosmetici o simili
PCT/IB2009/005634 WO2009144553A1 (en) 2008-05-27 2009-05-18 Bottle for containing injectable fluids, particularly medical, pharmaceutical, cosmetic products or the like

Publications (2)

Publication Number Publication Date
EP2303716A1 EP2303716A1 (de) 2011-04-06
EP2303716B1 true EP2303716B1 (de) 2012-07-11

Family

ID=40302884

Family Applications (1)

Application Number Title Priority Date Filing Date
EP20090754181 Not-in-force EP2303716B1 (de) 2008-05-27 2009-05-18 Flasche zur aufnahme von injizierbaren fluiden, insbesondere medizinischen, pharmazeutischen, kosmetischen produkten oder dergleichen

Country Status (4)

Country Link
EP (1) EP2303716B1 (de)
ES (1) ES2391068T3 (de)
IT (1) ITMO20080160A1 (de)
WO (1) WO2009144553A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015193772A1 (en) 2014-06-20 2015-12-23 Lameplast S.P.A. Procedure for the manufacture of strips of vials for fluid products, particularly for medical, pharmaceutical, cosmetic, food products or the like
EP3157831B1 (de) 2014-06-20 2019-07-31 LAMEPLAST S.p.A. Phiolenstreifen für flüssigprodukte, insbesondere für medizinische, pharmazeutische, kosmetische, lebensmittelprodukte und dergleichen
WO2016016764A1 (en) 2014-07-31 2016-02-04 Lameplast S.P.A. Strips of vials for fluid products, particularly for medical, pharmaceutical, cosmetic, food products or the like

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL8801643A (nl) * 1988-06-28 1990-01-16 Microplast Bv Werkwijze voor het vervaardigen van een dopsamenstel alsmede dopsamenstel.
GB2252099A (en) * 1991-01-21 1992-07-29 Martyn Neil Jones Safety valved cover for mouth of a vessel
DE4307803A1 (de) * 1993-03-12 1994-09-15 Hoechst Ag Verschluß mit Abreißdeckel für Injektions- und Infusionsflaschen
ES2261104B1 (es) * 2006-06-19 2007-06-16 Grifols, S.A. "tapon para frascos de productos esteriles y utilizacion de dicho tapon en la dosificacion esteril".

Also Published As

Publication number Publication date
EP2303716A1 (de) 2011-04-06
ITMO20080160A1 (it) 2009-11-28
ES2391068T3 (es) 2012-11-21
WO2009144553A1 (en) 2009-12-03

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