EP2284260A4 - Anti-(influenza a virus subtype h5 hemagglutinin) monoclonal antibody - Google Patents

Anti-(influenza a virus subtype h5 hemagglutinin) monoclonal antibody

Info

Publication number
EP2284260A4
EP2284260A4 EP09726058A EP09726058A EP2284260A4 EP 2284260 A4 EP2284260 A4 EP 2284260A4 EP 09726058 A EP09726058 A EP 09726058A EP 09726058 A EP09726058 A EP 09726058A EP 2284260 A4 EP2284260 A4 EP 2284260A4
Authority
EP
European Patent Office
Prior art keywords
hemagglutinin
influenza
monoclonal antibody
virus subtype
subtype
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP09726058A
Other languages
German (de)
French (fr)
Other versions
EP2284260A1 (en
Inventor
Hiroshi Kida
Yoshihiro Sakoda
Eiji Miyagawa
Nobuyuki Fujii
Yoshiaki Uchida
Takashi Shirakawa
Hiroyuki Kogaki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hokkaido University NUC
Fujirebio Inc
Original Assignee
Hokkaido University NUC
Fujirebio Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hokkaido University NUC, Fujirebio Inc filed Critical Hokkaido University NUC
Publication of EP2284260A1 publication Critical patent/EP2284260A1/en
Publication of EP2284260A4 publication Critical patent/EP2284260A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983—Viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • C07K16/1018—Orthomyxoviridae, e.g. influenza virus
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/005—Assays involving biological materials from specific organisms or of a specific nature from viruses
    • G01N2333/08—RNA viruses
    • G01N2333/11—Orthomyxoviridae, e.g. influenza virus
EP09726058A 2008-03-28 2009-03-26 Anti-(influenza a virus subtype h5 hemagglutinin) monoclonal antibody Withdrawn EP2284260A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2008088499 2008-03-28
PCT/JP2009/056083 WO2009119722A1 (en) 2008-03-28 2009-03-26 Anti-(influenza a virus subtype h5 hemagglutinin) monoclonal antibody

Publications (2)

Publication Number Publication Date
EP2284260A1 EP2284260A1 (en) 2011-02-16
EP2284260A4 true EP2284260A4 (en) 2011-08-10

Family

ID=41113910

Family Applications (1)

Application Number Title Priority Date Filing Date
EP09726058A Withdrawn EP2284260A4 (en) 2008-03-28 2009-03-26 Anti-(influenza a virus subtype h5 hemagglutinin) monoclonal antibody

Country Status (6)

Country Link
US (1) US8658354B2 (en)
EP (1) EP2284260A4 (en)
JP (1) JP5586064B2 (en)
KR (1) KR101625979B1 (en)
CN (1) CN101990575B (en)
WO (1) WO2009119722A1 (en)

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AU2011207626B2 (en) 2010-01-19 2015-06-18 President And Fellows Of Harvard College Engineered opsonin for pathogen detection and treatment
WO2011111108A1 (en) * 2010-03-11 2011-09-15 Ｄｉｃプラスチック株式会社 Instrument for enzyme-linked immunoassay, and enzyme-linked immunoassay
JP5630153B2 (en) * 2010-09-01 2014-11-26 富士レビオ株式会社 Method for determining whether the 100th amino acid of influenza A virus nucleoprotein is arginine
EP2646050B1 (en) * 2010-12-02 2016-09-07 mAB-Factory GmbH Vaccine against influenza h5n1 viruses, medicament and treatment of h5n1 viral infections
SG10201608671SA (en) 2011-07-18 2016-12-29 Harvard College Engineered Microbe-Targeting Molecules and Uses Thereof
JP5884100B2 (en) * 2011-08-31 2016-03-15 公益財団法人東京都医学総合研究所 Recombinant vaccinia virus derived from a DIs strain having a hemagglutinin protein gene derived from a new influenza virus
PL220281B1 (en) * 2011-09-23 2015-09-30 Inst Biochemii I Biofizyki Polskiej Akademii Nauk DNA vaccine, the method of inducing an immune response, the antibody specifically recognizing the protein of the influenza virus hemagglutinin H5 and the use of DNA vaccine
CN103030693B (en) * 2011-09-30 2015-03-11 中国科学院上海巴斯德研究所 Neutralization molecule of high-pathogenicity avian influenza and preparation method thereof
JP2013087069A (en) * 2011-10-17 2013-05-13 Toyobo Co Ltd Monoclonal antibody specifically recognizing h5 subtype influenza virus
RU2502745C2 (en) * 2011-12-30 2013-12-27 Общество с ограниченной ответственностью "Технофарма" Anti-flu nanoantibody, recombinant viral vectors and pharmaceutical compositions for prophylaxis and therapy of a-type flu
US9969794B2 (en) 2012-05-10 2018-05-15 Visterra, Inc. HA binding agents
CN102928605B (en) * 2012-11-06 2014-06-25 江苏省农业科学院 Indirect enzyme-linked immuno-sorbent assay (ELISA) kit for detecting similar porcine circovirus virus P1 antibody
EP2976642A4 (en) 2013-03-15 2016-09-21 Harvard College Methods and compositions for improving detection and/or capture of a target entity
CA2913155A1 (en) 2013-05-21 2014-11-27 President And Fellows Of Harvard College Engineered heme-binding compositions and uses thereof
CN113667012A (en) * 2013-10-02 2021-11-19 免疫医疗有限责任公司 Neutralizing anti-influenza a antibodies and uses thereof
US10513546B2 (en) 2013-12-18 2019-12-24 President And Fellows Of Harvard College CRP capture/detection of gram positive bacteria
CN103869067B (en) * 2014-04-01 2015-12-02 开封市疾病预防控制中心 A kind of influenza A virus colloidal gold diagnosis Test paper and preparation method thereof
SG11201608798YA (en) 2014-04-23 2016-11-29 Modernatx Inc Nucleic acid vaccines
WO2015186721A1 (en) * 2014-06-03 2015-12-10 国立研究開発法人農業・食品産業技術総合研究機構 Antibody or antibody fragment including variable region thereof, antigen polypeptide, and uses thereof
TWI702229B (en) 2014-12-19 2020-08-21 美商再生元醫藥公司 Human antibodies to influenza hemagglutinin
RU2618947C2 (en) * 2015-06-30 2017-05-11 Закрытое акционерное общество "Лаборатория Касперского" Method of preventing program operation comprising functional undesirable for user
EP3331549B1 (en) 2015-08-06 2020-12-23 President and Fellows of Harvard College Improved microbe-binding molecules and uses thereof
US11564893B2 (en) 2015-08-17 2023-01-31 Modernatx, Inc. Methods for preparing particles and related compositions
EP3374390A1 (en) 2015-11-13 2018-09-19 Visterra, Inc. Compositions and methods for treating and preventing influenza
US11576961B2 (en) 2017-03-15 2023-02-14 Modernatx, Inc. Broad spectrum influenza virus vaccine
US11230593B2 (en) 2019-03-25 2022-01-25 Visterra, Inc. Compositions and methods for treating and preventing influenza
CN114075278B (en) * 2020-08-18 2022-11-08 东莞市朋志生物科技有限公司 anti-Flu-A antibody, preparation method thereof and detection kit

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1814623A (en) * 2005-02-06 2006-08-09 厦门大学 H5 subtype avian flu virus hemagglutinin protein monoclonal antibody, and its preparing method and use
WO2007074812A1 (en) * 2005-12-26 2007-07-05 Bl Co., Ltd. Method for detection of influenza type-a virus subtype h5
JP2007261988A (en) * 2006-03-28 2007-10-11 Osaka Prefecture Specific detection of h5 subtype influenza virus
WO2009099394A1 (en) * 2008-02-05 2009-08-13 Temasek Life Sciences Laboratory Limited Binding protein and epitope-blocking elisa for the universal detection of h5-subtype influenza viruses

Family Cites Families (3)

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JP5525688B2 (en) * 2005-08-19 2014-06-18 株式会社ビーエル Immunodetection method for influenza virus H5 subtype
JP5300200B2 (en) * 2006-08-31 2013-09-25 大阪府 Rapid diagnostic method specific to avian influenza virus
JP5435844B2 (en) * 2007-02-13 2014-03-05 株式会社ビーエル Immunodetection method for influenza virus H5 subtype

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1814623A (en) * 2005-02-06 2006-08-09 厦门大学 H5 subtype avian flu virus hemagglutinin protein monoclonal antibody, and its preparing method and use
WO2007074812A1 (en) * 2005-12-26 2007-07-05 Bl Co., Ltd. Method for detection of influenza type-a virus subtype h5
JP2007261988A (en) * 2006-03-28 2007-10-11 Osaka Prefecture Specific detection of h5 subtype influenza virus
WO2009099394A1 (en) * 2008-02-05 2009-08-13 Temasek Life Sciences Laboratory Limited Binding protein and epitope-blocking elisa for the universal detection of h5-subtype influenza viruses

Non-Patent Citations (14)

* Cited by examiner, † Cited by third party
Title
DATABASE WPI Week 200682, Derwent World Patents Index; AN 2006-801394, XP002643481, CHEN H.: "H5 subtype avian flu virus hemagglutinin protein monoclonal antibody, and its preparing method and use" *
DATABASE WPI Week 200753, Derwent World Patents Index; AN 2007-545603, XP002643506, NAMBA: "Detecting influenza type-A virus subtype H5, involves performing immunoassay using first antibody reacting with respect to all influenza A virus subtypes and second antibody reacting with respect to influenza A virus subtypes H5" *
DATABASE WPI Week 200776, Derwent World Patents Index; AN 2007-810126, XP002643507, NISHIMURA: "SPECIFIC DETECTION OF H5 SUBTYPE INFLUENZA VIRUS" *
EMI TSUCHIYA ET AL: "Antigenic structure of the haemagglutinin of human influenza A/H2N2 virus", JOURNAL OF GENERAL VIROLOGY, vol. 82, 1 January 2001 (2001-01-01), pages 2475 - 2484, XP055067866 *
HA YA ET AL: "X-ray structures of H5 avian and H9 swine influenza virus hemagglutinins bound to avian and human receptor analogs", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES, NATIONAL ACADEMY OF SCIENCES, WASHINGTON, DC; US, vol. 98, no. 20, 25 September 2001 (2001-09-25), pages 11181 - 11186, XP002593759, ISSN: 0027-8424, DOI: 10.1073/PNAS.201401198 *
KAVERIN NIKOLAI V ET AL: "Epitope mapping of the hemagglutinin molecule of a highly pathogenic H5N1 influenza virus by using", JOURNAL OF VIROLOGY, vol. 81, no. 23, December 2007 (2007-12-01), pages 12911 - 12917, XP055000999, ISSN: 0022-538X *
KAVERIN NIKOLAI V ET AL: "Structure of antigenic sites on the haemagglutinin molecule of H5 avian influenza virus and phenotypic variation of escape mutants", JOURNAL OF GENERAL VIROLOGY, SOCIETY FOR GENERAL MICROBIOLOGY, SPENCERS WOOD, GB, vol. 83, no. Pt 10, 1 October 2002 (2002-10-01), pages 2497 - 2505, XP002547472, ISSN: 0022-1317 *
LIAO ZHI-YONG ET AL: "Production of monoclonal antibodies specific to H5 hemagglutinin of avian influenza virus and establishment of the H5 antigen capture ELISA", IMMUNOLOGICAL JOURNAL = MIANYIXUE ZAZHI, CHINA, vol. 23, no. 3, 1 January 2007 (2007-01-01), pages 339 - 343, XP008138074, ISSN: 1000-8861, DOI: CNKI:ISSN:1000-8861.0.2007-03-025 *
PHILPOTT M ET AL: "HEMAGGLUTININ MUTATIONS RELATED TO ATTENUATION AND ALTERED CELL TROPISM OF A VIRULENT AVIAN INFLUENZA A VIRUS", JOURNAL OF VIROLOGY, vol. 64, no. 6, 1990, pages 2941 - 2947, XP055000955, ISSN: 0022-538X *
PHILPOTT M ET AL: "Neutralizing epitopes of the H5 hemagglutinin from a virulent avian influenza virus and their relationship to pathogenicity", JOURNAL OF VIROLOGY, THE AMERICAN SOCIETY FOR MICROBIOLOGY, US, vol. 63, no. 8, 1 August 1989 (1989-08-01), pages 3453 - 3458, XP003002755, ISSN: 0022-538X *
Q. HE ET AL: "Detection of H5 Avian Influenza Viruses by Antigen-Capture Enzyme-Linked Immunosorbent Assay Using H5-Specific Monoclonal Antibody", CLINICAL AND VACCINE IMMUNOLOGY, vol. 14, no. 5, 1 May 2007 (2007-05-01), pages 617 - 623, XP055000849, ISSN: 1556-6811, DOI: 10.1128/CVI.00444-06 *
See also references of WO2009119722A1 *
SMIRNOV Y A ET AL: "An epitope shared by the hemagglutinins of H1, H2, H5, and H6 subtypes of influenza A virus", ACTA VIROLOGICA, ACADEMIA PRAGUE, PRAGUE, CS, vol. 43, no. 4, 1 August 1999 (1999-08-01), pages 237 - 244, XP009095964, ISSN: 0001-723X *
TSUDA Y ET AL: "Development of an immunochromatographic kit for rapid diagnosis of H5 avian influenza virus infection", MICROBIOLOGY AND IMMUNOLOGY, CENTER FOR ACADEMIC PUBLICATIONS JAPAN, JP, vol. 51, no. 9, 1 September 2007 (2007-09-01), pages 903 - 907, XP002526101, ISSN: 0385-5600 *

Also Published As

Publication number Publication date
US8658354B2 (en) 2014-02-25
JPWO2009119722A1 (en) 2011-07-28
US20110065095A1 (en) 2011-03-17
JP5586064B2 (en) 2014-09-10
CN101990575A (en) 2011-03-23
KR101625979B1 (en) 2016-05-31
WO2009119722A1 (en) 2009-10-01
CN101990575B (en) 2015-06-17
EP2284260A1 (en) 2011-02-16
KR20100124720A (en) 2010-11-29

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RIC1 Information provided on ipc code assigned before grant

Ipc: G01N 33/577 20060101ALI20110630BHEP

Ipc: G01N 33/569 20060101ALI20110630BHEP

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Owner name: NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSIT

Owner name: FUJIREBIO INC.

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