EP2268278A4 - PHARMACEUTICAL COMPOSITION - Google Patents

PHARMACEUTICAL COMPOSITION

Info

Publication number
EP2268278A4
EP2268278A4 EP08742562A EP08742562A EP2268278A4 EP 2268278 A4 EP2268278 A4 EP 2268278A4 EP 08742562 A EP08742562 A EP 08742562A EP 08742562 A EP08742562 A EP 08742562A EP 2268278 A4 EP2268278 A4 EP 2268278A4
Authority
EP
European Patent Office
Prior art keywords
pharmaceutical composition
pharmaceutical
composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP08742562A
Other languages
German (de)
English (en)
French (fr)
Other versions
EP2268278A1 (en
Inventor
Paul Bingham
Lakmal W Boteju
Zuzana Zachar
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of EP2268278A1 publication Critical patent/EP2268278A1/en
Publication of EP2268278A4 publication Critical patent/EP2268278A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/385—Heterocyclic compounds having sulfur as a ring hetero atom having two or more sulfur atoms in the same ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
EP08742562A 2008-04-04 2008-04-04 PHARMACEUTICAL COMPOSITION Withdrawn EP2268278A4 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2008/004410 WO2009123597A1 (en) 2008-04-04 2008-04-04 Pharmaceutical composition

Publications (2)

Publication Number Publication Date
EP2268278A1 EP2268278A1 (en) 2011-01-05
EP2268278A4 true EP2268278A4 (en) 2011-11-09

Family

ID=41135840

Family Applications (1)

Application Number Title Priority Date Filing Date
EP08742562A Withdrawn EP2268278A4 (en) 2008-04-04 2008-04-04 PHARMACEUTICAL COMPOSITION

Country Status (10)

Country Link
EP (1) EP2268278A4 (pt)
JP (1) JP2011516473A (pt)
KR (1) KR20110025168A (pt)
CN (1) CN102056605A (pt)
AU (1) AU2008354009A1 (pt)
BR (1) BRPI0821894A2 (pt)
CA (1) CA2720396A1 (pt)
IL (1) IL208387A0 (pt)
MX (1) MX2010010867A (pt)
WO (1) WO2009123597A1 (pt)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX343847B (es) 2010-07-08 2016-11-24 Wrigley W M Jun Co Goma de mascar que contiene una base de goma de matriz de gelatina reticulada.
US9421234B2 (en) * 2011-05-20 2016-08-23 Nutramax Laboratories, Inc. Orally administrable compositions comprising avocado/soybean unsaponifiables and lipoic acid and methods of administration
CA2863600A1 (en) * 2012-02-16 2013-08-22 The Penn State Research Foundation Modulators of acyl-coa lysocardiolipin acyltransferase 1 ( alcat1) and uses thereof
CN105142643B (zh) * 2012-12-19 2021-09-03 基石医药公司 药物化合物
AU2014398232B2 (en) 2014-06-19 2019-11-28 Rafael Pharmaceuticals, Inc. Pharmaceutical compounds
WO2015195071A1 (en) 2014-06-19 2015-12-23 Robert Shorr Pharmaceutical compounds
CN110590624B (zh) * 2019-09-26 2021-02-26 苏州富士莱医药股份有限公司 一种硫辛酸衍生物8-(乙基二硫基)-6-(苯基二硫基)辛酸的制备方法
WO2023012305A1 (en) * 2021-08-04 2023-02-09 Cytacoat Ab Disulfide compounds as medicaments

Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2789991A (en) * 1954-05-20 1957-04-23 American Cyanamid Co Substituted disulfones
US2853497A (en) * 1953-12-04 1958-09-23 Merck & Co Inc 6, 8-bis (hydrocarbon substituted mercapto) 5-hydroxycaprylic acids and delta-lactones thereof
JPS61198148A (ja) * 1985-01-29 1986-09-02 Fuji Photo Film Co Ltd ハロゲン化銀写真感光材料
EP0947503A1 (fr) * 1998-04-01 1999-10-06 Galderma Research & Development, S.N.C. Dérivés de l'acide 6,8-dimercaptooctanoique substitués en 6-S et/ou 8-S par le radical (3-methylthiopropanoyl) et compositions pharmaceutiques destinées au traitement de tumeurs cancéreuses
WO2000059899A1 (fr) * 1999-04-02 2000-10-12 Societe De Conseil De Recherches Et D'applications Scientifiques (S.C.R.A.S.) Nouveaux derives de l'acide lipoïque et les compositions pharmaceutiques les contenant
WO2000061143A1 (en) * 1999-04-09 2000-10-19 Antibioticos S.P.A. The use of alpha lipoic acid in the antimetastatic treatment
WO2008131114A2 (en) * 2007-04-18 2008-10-30 Cornerstone Pharmaceuticals, Inc. Pharmaceutical formulations containing lipoic acid derivatives
WO2008131117A1 (en) * 2007-04-18 2008-10-30 Cornerstone Pharmaceuticals, Inc. Lipoic acid derivatives
WO2009110859A1 (en) * 2008-03-04 2009-09-11 Robert Shorr Modulation of enzymatic structure, activity, and/or expression level

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9618934D0 (en) * 1996-09-11 1996-10-23 Univ London Inositol phosphoglycans for therapeutic use in the treatment of diabetes and obesity
DK1624060T3 (da) * 1998-03-20 2012-04-10 Commw Scient Ind Res Org Kontrol af genekspression
US6331559B1 (en) * 1998-10-26 2001-12-18 The Research Foundation Of State University Of New York At Stony Brook Lipoic acid derivatives and their use in treatment of disease
DE19904794A1 (de) * 1999-02-05 2000-08-10 Biotechnolog Forschung Gmbh Verfahren zur Verbesserung des Primärstoffwechsels von Säugerzelllinien
US6284786B1 (en) * 1999-02-16 2001-09-04 The Center For The Improvement Of Human Functioning, Int'l., Inc. Treatment of cancer using lipoic acid in combination with ascorbic acid
US7108977B2 (en) * 2000-05-19 2006-09-19 Hoffmann-La Roche Inc. Process for determining the tumoricidal potential of a sample the use of a nucleic acid which is downregulated in human tumor cells
WO2006119355A2 (en) * 2005-05-03 2006-11-09 Albert Einstein College Of Medicine Of Yeshiva University Mammalian hypothalamic nutrient modulation of glucose metabolism
US20070077583A1 (en) * 2005-09-21 2007-04-05 Aurelium Biopharma, Inc. Alpha enolase-directed diagnostics and therapeutics for cancer and chemotherapeutic drug resistance
US20070212360A1 (en) * 2006-01-17 2007-09-13 Denko Nicholas C Modulation of mitochondrial oxygen consumption for therapeutic purposes

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2853497A (en) * 1953-12-04 1958-09-23 Merck & Co Inc 6, 8-bis (hydrocarbon substituted mercapto) 5-hydroxycaprylic acids and delta-lactones thereof
US2789991A (en) * 1954-05-20 1957-04-23 American Cyanamid Co Substituted disulfones
JPS61198148A (ja) * 1985-01-29 1986-09-02 Fuji Photo Film Co Ltd ハロゲン化銀写真感光材料
EP0947503A1 (fr) * 1998-04-01 1999-10-06 Galderma Research & Development, S.N.C. Dérivés de l'acide 6,8-dimercaptooctanoique substitués en 6-S et/ou 8-S par le radical (3-methylthiopropanoyl) et compositions pharmaceutiques destinées au traitement de tumeurs cancéreuses
WO2000059899A1 (fr) * 1999-04-02 2000-10-12 Societe De Conseil De Recherches Et D'applications Scientifiques (S.C.R.A.S.) Nouveaux derives de l'acide lipoïque et les compositions pharmaceutiques les contenant
WO2000061143A1 (en) * 1999-04-09 2000-10-19 Antibioticos S.P.A. The use of alpha lipoic acid in the antimetastatic treatment
WO2008131114A2 (en) * 2007-04-18 2008-10-30 Cornerstone Pharmaceuticals, Inc. Pharmaceutical formulations containing lipoic acid derivatives
WO2008131117A1 (en) * 2007-04-18 2008-10-30 Cornerstone Pharmaceuticals, Inc. Lipoic acid derivatives
WO2009110859A1 (en) * 2008-03-04 2009-09-11 Robert Shorr Modulation of enzymatic structure, activity, and/or expression level

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
COURVOISIER C ET AL: "Synthesis and effects of 3-methylthiopropanoyl thiolesters of lipoic acid, methional metabolite mimics", BIOORGANIC CHEMISTRY, ACADEMIC PRESS INC., NEW YORK, NY, US, vol. 34, no. 1, 1 February 2006 (2006-02-01), pages 49 - 58, XP024896857, ISSN: 0045-2068, [retrieved on 20060201], DOI: 10.1016/J.BIOORG.2005.11.001 *
FELLER DENNIS R ET AL: "Selective PPARgamma versus PPARalpha agonist activity of a novel set of alpha-lipoic acid analogs of thiazolidinediones", FASEB JOURNAL, FED. OF AMERICAN SOC. FOR EXPERIMENTAL BIOLOGY, US, vol. 17, no. 4-5, 1 March 2003 (2003-03-01), pages A1061, XP009133351, ISSN: 0892-6638 *
HYK W ET AL: "The extreme migrational enhancement of faradaic current at microelectrodes: experimental studies on sodium (6,8-diferrocenylmethylthio)octanoate electrooxidation", JOURNAL OF ELECTROANALYTICAL CHEMISTRY AND INTERFACIALELECTRO CHEMISTRY, ELSEVIER, AMSTERDAM, NL, vol. 575, no. 2, 1 February 2005 (2005-02-01), pages 321 - 328, XP025373180, ISSN: 0022-0728, [retrieved on 20050201] *
MARK VAN DE K ET AL: "ALPHA-LIPOIC ACID INDUCES P27KIP-DEPENDENT CELL CYCLE ARREST IN NON-TRANSFORMED CELL LINES AND APOPTOSIS IN TUMOR CELL LINES", JOURNAL OF CELLULAR PHYSIOLOGY, WILEY LISS, NEW YORK, NY, US, vol. 194, no. 3, 1 March 2003 (2003-03-01), pages 325 - 340, XP008037152, ISSN: 0021-9541, DOI: 10.1002/JCP.10205 *
SATOH ET AL: "Simultaneous determination of alpha-lipoic acid and its reduced form by high-performance liquid chromatography with fluorescence detection", JOURNAL OF CHROMATOGRAPHY B: BIOMEDICAL SCIENCES & APPLICATIONS, ELSEVIER, AMSTERDAM, NL, vol. 854, no. 1-2, 25 June 2007 (2007-06-25), pages 109 - 115, XP022127447, ISSN: 1570-0232, DOI: 10.1016/J.JCHROMB.2007.04.003 *
See also references of WO2009123597A1 *

Also Published As

Publication number Publication date
BRPI0821894A2 (pt) 2015-07-21
AU2008354009A1 (en) 2009-10-08
WO2009123597A1 (en) 2009-10-08
EP2268278A1 (en) 2011-01-05
JP2011516473A (ja) 2011-05-26
CN102056605A (zh) 2011-05-11
MX2010010867A (es) 2011-05-25
CA2720396A1 (en) 2009-10-08
IL208387A0 (en) 2010-12-30
KR20110025168A (ko) 2011-03-09

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Legal Events

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A4 Supplementary search report drawn up and despatched

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