EP2234630A4 - Verfahren zur stimulierung der motilität des gastrointestinal-systems mit ipamorelin - Google Patents

Verfahren zur stimulierung der motilität des gastrointestinal-systems mit ipamorelin

Info

Publication number
EP2234630A4
EP2234630A4 EP08864278A EP08864278A EP2234630A4 EP 2234630 A4 EP2234630 A4 EP 2234630A4 EP 08864278 A EP08864278 A EP 08864278A EP 08864278 A EP08864278 A EP 08864278A EP 2234630 A4 EP2234630 A4 EP 2234630A4
Authority
EP
European Patent Office
Prior art keywords
ipamorelin
motility
stimulating
gastrointestinal system
gastrointestinal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP08864278A
Other languages
English (en)
French (fr)
Other versions
EP2234630A1 (de
Inventor
William J Polvino
Richard Nelson
William R Mann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Helsinn Healthcare SA
Original Assignee
Helsinn Therapeutics US Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Helsinn Therapeutics US Inc filed Critical Helsinn Therapeutics US Inc
Publication of EP2234630A1 publication Critical patent/EP2234630A1/de
Publication of EP2234630A4 publication Critical patent/EP2234630A4/de
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/25—Growth hormone-releasing factor [GH-RF], i.e. somatoliberin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/10—Laxatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Nutrition Science (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
EP08864278A 2007-12-21 2008-11-26 Verfahren zur stimulierung der motilität des gastrointestinal-systems mit ipamorelin Withdrawn EP2234630A4 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US882807P 2007-12-21 2007-12-21
PCT/US2008/013156 WO2009082426A1 (en) 2007-12-21 2008-11-26 Method of stimulating the motility of the gastrointestinal system using ipamorelin

Publications (2)

Publication Number Publication Date
EP2234630A1 EP2234630A1 (de) 2010-10-06
EP2234630A4 true EP2234630A4 (de) 2012-08-08

Family

ID=40801504

Family Applications (1)

Application Number Title Priority Date Filing Date
EP08864278A Withdrawn EP2234630A4 (de) 2007-12-21 2008-11-26 Verfahren zur stimulierung der motilität des gastrointestinal-systems mit ipamorelin

Country Status (8)

Country Link
EP (1) EP2234630A4 (de)
JP (2) JP2011507842A (de)
KR (1) KR20100102157A (de)
CN (1) CN101951937A (de)
AU (1) AU2008341160A1 (de)
CA (1) CA2709913A1 (de)
TW (1) TW200940082A (de)
WO (1) WO2009082426A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PE20121064A1 (es) * 2009-06-12 2012-09-03 Helsinn Therapeutics Us Inc Solucion de inyeccion o infusion de diacetato de ipamorelin
WO2014156339A1 (ja) 2013-03-25 2014-10-02 ゼリア新薬工業株式会社 食後期の胃運動亢進剤
IL262328B2 (en) * 2016-04-13 2023-04-01 Univ Nebraska Methods for administration and methods for treating cardiovascular diseases with resiniparatoxin

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2321026A1 (en) * 1998-03-09 1999-09-16 Zealand Pharmaceuticals A/S Pharmacologically active peptide conjugates having a reduced tendency towards enzymatic hydrolysis
ES2333097T3 (es) * 2000-05-31 2010-02-17 Raqualia Pharma Inc Uso de secretagogos de la hormona de crecimiento para estimular la motilidad gastrointestinal.
PL374481A1 (en) * 2002-07-05 2005-10-31 Chugai Seiyaku Kabushiki Kaisha Remedy for diabetes
US7476653B2 (en) * 2003-06-18 2009-01-13 Tranzyme Pharma, Inc. Macrocyclic modulators of the ghrelin receptor
US7491695B2 (en) * 2003-06-18 2009-02-17 Tranzyme Pharma Inc. Methods of using macrocyclic modulators of the ghrelin receptor
WO2006020930A2 (en) * 2004-08-12 2006-02-23 Sapphire Therapeutics, Inc. Method of stimulating the motility of the gastrointestinal system using growth hormone secretagogues
PT1937262T (pt) * 2005-09-29 2019-08-21 Ipsen Pharma Sas Composição para utilização no tratamento de dismotilidade gastrointestinal

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
KALINA VENKOVA ET AL: "Prokinetic Effects of a New Ghrelin Receptor Agonist TZP-101 in a Rat Model of Postoperative Ileus", DIGESTIVE DISEASES AND SCIENCES, KLUWER ACADEMIC PUBLISHERS-PLENUM PUBLISHERS, NE, vol. 52, no. 9, 10 April 2007 (2007-04-10), pages 2241 - 2248, XP019526062, ISSN: 1573-2568, DOI: 10.1007/S10620-007-9783-7 *
MURRAY1 C D R ET AL: "Ghrelin enhances gastric emptying in diabetic gastroparesis: a double blind, placebo controlled crossover study", GUT, BRITISH MEDICAL ASSOCIATION, LONDON, UK, vol. 54, 5 August 2005 (2005-08-05), pages 1693 - 1698, XP008126776, ISSN: 0017-5749, DOI: 10.1136/GUT.2005.069088 *
PEETERS ET AL: "Potential of ghrelin as a therapeutic approach for gastrointestinal motility disorders", CURRENT OPINION IN PHARMACOLOGY, ELSEVIER SCIENCE PUBLISHERS, NL, vol. 6, no. 6, 1 December 2006 (2006-12-01), pages 553 - 558, XP028058476, ISSN: 1471-4892, [retrieved on 20061201], DOI: 10.1016/J.COPH.2006.08.005 *
POITRAS P ET AL: "Gastrokinetic effect of ghrelin analog RC-1139 in the rat", PEPTIDES, ELSEVIER, AMSTERDAM, vol. 26, no. 9, 1 September 2005 (2005-09-01), pages 1598 - 1601, XP027856463, ISSN: 0196-9781, [retrieved on 20050901] *
See also references of WO2009082426A1 *

Also Published As

Publication number Publication date
KR20100102157A (ko) 2010-09-20
TW200940082A (en) 2009-10-01
JP2011507842A (ja) 2011-03-10
AU2008341160A1 (en) 2009-07-02
CN101951937A (zh) 2011-01-19
CA2709913A1 (en) 2009-07-02
EP2234630A1 (de) 2010-10-06
WO2009082426A1 (en) 2009-07-02
JP2013040206A (ja) 2013-02-28

Similar Documents

Publication Publication Date Title
GB2479092B (en) Facial stimulation apparatus
HK1208237A1 (en) Methods for the treatment of gout
EP2125100A4 (de) Muskelstimulator
EP2192948A4 (de) Vorhofstimulationssystem
EP2138147A4 (de) Massagevorrichtung
GB0715346D0 (en) Stimulator
GB2461155B (en) Mine detonating apparatus
IL212011A0 (en) Stimulation apparatus
EP2059211A4 (de) Sexuelles stimulationsgerät
GB2455402B (en) Stimulation aid
GB0725348D0 (en) Method of authentication
GB0718684D0 (en) Treatment method
EP2234630A4 (de) Verfahren zur stimulierung der motilität des gastrointestinal-systems mit ipamorelin
GB0722274D0 (en) New therapeutic method
EP2203432A4 (de) Behandlungsverfahren
EP2255823A4 (de) Darm-immunsystem-stimulator
GB0721924D0 (en) Method of remote authentication
GB0721925D0 (en) Method of remote authentication
GB0715160D0 (en) Spa treatment apparatus
GB0918243D0 (en) Stimulation apparatus
GB0715307D0 (en) Therapeutic method
ZA201100162B (en) Walking aid apparatus
TWM341515U (en) Multifunctional sauna apparatus
GB0717337D0 (en) Method of treatment
GB0812723D0 (en) Hydrotherapy spa

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20100716

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MT NL NO PL PT RO SE SI SK TR

AX Request for extension of the european patent

Extension state: AL BA MK RS

DAX Request for extension of the european patent (deleted)
REG Reference to a national code

Ref country code: HK

Ref legal event code: DE

Ref document number: 1149197

Country of ref document: HK

A4 Supplementary search report drawn up and despatched

Effective date: 20120706

RIC1 Information provided on ipc code assigned before grant

Ipc: A61K 31/4164 20060101ALI20120702BHEP

Ipc: A61K 45/06 20060101ALI20120702BHEP

Ipc: A61K 38/04 20060101AFI20120702BHEP

Ipc: A61P 1/00 20060101ALI20120702BHEP

Ipc: A61K 31/33 20060101ALI20120702BHEP

RAP1 Party data changed (applicant data changed or rights of an application transferred)

Owner name: HELSINN HEALTHCARE S.A.

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20150602

REG Reference to a national code

Ref country code: HK

Ref legal event code: WD

Ref document number: 1149197

Country of ref document: HK