EP2196170B1 - Beutel und Beutelverbund für die Verpackung einer flüssigen biologischen Substanz, wie beispielsweise Tiersamen - Google Patents
Beutel und Beutelverbund für die Verpackung einer flüssigen biologischen Substanz, wie beispielsweise Tiersamen Download PDFInfo
- Publication number
- EP2196170B1 EP2196170B1 EP09178192.2A EP09178192A EP2196170B1 EP 2196170 B1 EP2196170 B1 EP 2196170B1 EP 09178192 A EP09178192 A EP 09178192A EP 2196170 B1 EP2196170 B1 EP 2196170B1
- Authority
- EP
- European Patent Office
- Prior art keywords
- sachet
- needle
- filling
- bag
- set according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 239000000126 substance Substances 0.000 title claims description 16
- 210000000582 semen Anatomy 0.000 title claims description 8
- 239000007788 liquid Substances 0.000 title claims description 7
- 238000004806 packaging method and process Methods 0.000 title claims description 5
- 238000003466 welding Methods 0.000 claims description 8
- 239000011324 bead Substances 0.000 claims description 3
- 229920002457 flexible plastic Polymers 0.000 claims description 3
- 239000000463 material Substances 0.000 claims description 2
- 230000000149 penetrating effect Effects 0.000 claims description 2
- 239000006260 foam Substances 0.000 description 10
- 230000009027 insemination Effects 0.000 description 6
- 210000002105 tongue Anatomy 0.000 description 6
- 239000002985 plastic film Substances 0.000 description 4
- 239000010408 film Substances 0.000 description 3
- 239000004033 plastic Substances 0.000 description 2
- 229920003023 plastic Polymers 0.000 description 2
- 229920006255 plastic film Polymers 0.000 description 2
- -1 polyethylene Polymers 0.000 description 2
- 229920000139 polyethylene terephthalate Polymers 0.000 description 2
- 239000005020 polyethylene terephthalate Substances 0.000 description 2
- 239000000523 sample Substances 0.000 description 2
- 238000007790 scraping Methods 0.000 description 2
- 238000007789 sealing Methods 0.000 description 2
- 102000009027 Albumins Human genes 0.000 description 1
- 108010088751 Albumins Proteins 0.000 description 1
- 239000004952 Polyamide Substances 0.000 description 1
- 239000004698 Polyethylene Substances 0.000 description 1
- 238000003556 assay Methods 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 150000001860 citric acid derivatives Chemical class 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 239000003085 diluting agent Substances 0.000 description 1
- 238000010790 dilution Methods 0.000 description 1
- 239000012895 dilution Substances 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000005187 foaming Methods 0.000 description 1
- 230000000977 initiatory effect Effects 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 230000002572 peristaltic effect Effects 0.000 description 1
- 229920002647 polyamide Polymers 0.000 description 1
- 229920000573 polyethylene Polymers 0.000 description 1
- 239000003755 preservative agent Substances 0.000 description 1
- 230000000750 progressive effect Effects 0.000 description 1
- 230000000717 retained effect Effects 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 235000000346 sugar Nutrition 0.000 description 1
- 150000008163 sugars Chemical class 0.000 description 1
- 239000010409 thin film Substances 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
- A61D19/00—Instruments or methods for reproduction or fertilisation
- A61D19/02—Instruments or methods for reproduction or fertilisation for artificial insemination
- A61D19/022—Containers for animal semen, e.g. pouches or vials ; Methods or apparatus for treating or handling animal semen containers, e.g. filling or closing
Definitions
- the present invention relates to an assembly consisting of a hollow needle and a packaging bag of a liquid biological substance, such as animal semen.
- the document WO 94/22731 A discloses a bag adapted for packaging a liquid biological substance according to the preamble of claim 1.
- the document WO 02/32469 A discloses an assembly consisting of a needle and a blood bag.
- These bags are formed of two flexible plastic films joined and welded, usually by heat sealing, delimiting a substance receiving pocket.
- the filling of the bags is done on a machine specially adapted for this purpose, in which the band of bags scrolls step by step.
- the bags are suspended in a vertical position so that their filling opening is directed upwards.
- the desired dose of substance is delivered by means of a hollow needle, via a flexible supply line, one end of which is connected to a container containing the substance and the other to the hollow needle; the duct is equipped with a peristaltic pump that ensures accurate dose distribution.
- the band of bags is stopped, and the needle, which is also vertical, enters the opening of the bag to be filled and goes down inside the pocket, until approximately mid-height of it, or even lower; the dose of substance is injected into the bag by the lower end of the needle, then the needle is withdrawn by a vertical movement from bottom to top, after which the area of the opening is closed by thermo welding.
- the substance is pushed out of the bag and brought to the insemination probe, either through the same opening, after opening the welded zone, or by means of a cannula arranged to the opposite end of the bag, for example according to the teachings of the document EP-B-1 317 224 .
- the substance is composed of boar semen mixed with a diluent liquid containing preservatives such as sugars, citrates and albumin, which make the substance foaming.
- foam at the time of filling is favored by the relatively high flow rate of the substance when it leaves the needle, a high flow rate being necessary so that the filling of the bags can be done at a suitable rate (generally 2 seconds approximately per sachet).
- This foam has a tendency to adhere to the needle and accompany it during its withdrawal, in the area of the opening in which the welding must take place, or even outside this area.
- a fraction of the seed is removed from the bag, which is not satisfactory for the accuracy of the assay.
- the possible presence of seed outside the bag is a possible cause of unexpected transfer of spermatozoa from one bag to another within a lot of sachets filled and stored side by side; the liquid out of the bag may also alter the marking, by dilution of the ink, which may in particular pose difficulties for reading identification tags.
- the present invention aims to solve these difficulties by preventing the foam thus formed from accompanying the injection needle during removal from the filling opening of the bag.
- the invention therefore relates to an assembly consisting of a needle and a packaging bag of a liquid biological substance, such as animal semen, formed of two flexible plastic films contiguous and welded, delimiting a receiving pocket. of the substance, which has at one of its ends an opening for filling the empty bag by means of a hollow cylindrical needle.
- a liquid biological substance such as animal semen
- these films have a pair of mutual welding lines, which form tabs starting from said opening and penetrating axially and symmetrically into the internal space of the bag. converging towards the inside thereof, their free ends being separated by a value "e" which is substantially equal to ⁇ d / 2, "d” being the value of the diameter of said needle.
- the two welded lines converge forming an apex angle whose value ⁇ is between 20 and 60 °, advantageously close to 45 °, which performs a particularly effective scraping and cleaning of the needle.
- the bag 1 represented on the figure 1 is intended to contain boar semen for subsequent artificial insemination of a sow.
- Each sachet has an elongated rectangular overall shape, the major axis of symmetry of which is designated X-X '. Its contour is delimited by two welded lateral edges 10, a first closed end zone 11 (bottom), also welded, and a second end zone comprising two welded zones 12a, 12b separated by an opening 4 for filling.
- This plastics material is preferably transparent or translucent and consists for example of polyethylene, polyamide or polyethylene terephthalate (PET).
- PET polyethylene terephthalate
- the two films are preferably made of two separate sheets. However, one can make use of one and the same sheet that has been folded on itself.
- Each sheet can be single or multilayer
- the bag 1 is separated from the two adjacent bags 1A and 1B by precut lines 100A, respectively 100B, connecting end perforations 101-102, as is well known.
- zones 12a and 12b are drilled openings 3, 3 'which serve to receive the driving fingers and retaining the bags, in the suspended position, in the filling machine.
- one 3 'of these orifices has an oblong shape, being formed of two circular holes partially overlapping.
- a dump cannula 2 In the bottom zone 11 is integrated a dump cannula 2, axis X-X ', integrated in the bag, for example in accordance with the teachings of the document EP-B-1 317 224 .
- the longitudinal edges of the strip, outside the zones 12a-12b and the filling opening 4 are disjoint (not welded) and can therefore be spaced freely from one another.
- the opening 4 has a main portion 6, which will be designated conventionally "mouth”, delimited by the edges vis-à-vis the welded portions 12a and 12b, which edges are parallel to the axis XX 'and spaced apart. a distance "a”. These edges extend inside the bag by weld lines 7 in the form of straight tabs. These are inclined symmetrically with respect to the median axis X-X 'so as to converge towards the inside of the bag, forming a cut-off "V".
- This value "e” is adapted to the diameter "d" of the hollow needle used for filling, so that when the needle passes axially through the opening 6 it pushes the areas of plastic film around this narrowed passage, referenced 70 on the figure 1 , making him take a circular shape of corresponding diameter.
- the value "e” is substantially equal to 1 ⁇ 2 ⁇ d.
- the width "a" of the mouth zone 6 is significantly larger than the diameter "d" of the needle 8.
- the needle 8 is withdrawn by an axial translation movement from bottom to top, symbolized by the arrow F on the figure 2 .
- the reference M denotes foam adhering against the wall of the needle 8.
- the ends of the tongues 7, such as flexible lips, as well as the edges of plastic film at the right of the narrowed passage 70 scrape this wall and retain the foam M, by deflecting laterally under the oblique welding lines 7, as symbolized by the arrows G.
- the foam remains trapped inside the bag, without contaminating the mouth 6, according to the desired objective.
- the filling opening is then closed tightly, under good conditions, by a heat-sealing line 9.
- the tongues 7 each have a bulge-shaped end expansion 71.
- the presence of the beads 71 reinforces the ends of the tongues by limiting the risk of initiation of rupture at this level when the bag is subjected to high mechanical stresses, including torsion, for emptying during insemination ( via the cannula 2).
- Variant 5 illustrates another possible shutter mode of the bag after filling.
- this passage opens with a 90 profile V-shaped area.
- the filling opening 4 can also be used for emptying, which is particularly useful for closed-bottomed bags, as described for example in the document FR-A-2,667,504 .
- the passage 91 acts as emptying duct and the portion 90 of centering cone for the introduction of the insemination probe.
- a needle with a bevelled end is used with conventional bags to facilitate its introduction into the bag, but which presents a risk of the flow of a small quantity of substance retained in the needle, after it has been removed from the bag.
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Reproductive Health (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Bag Frames (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
Claims (6)
- Einheit, gebildet aus einer hohlen Nadel (8) mit dem Durchmesser "d" und einem Verpackungsbeutel einer flüssigen biologischen Substanz wie Tiersamen, gebildet aus zwei aneinander anliegenden und verschweißten Folien aus geschmeidigem Kunststoffmaterial, der eine Aufnahmetasche der Substanz begrenzen, die an einem ihrer Enden eine Öffnung (4) aufweist, die das Befüllen des leeren Beutels mit Hilfe einer hohlen zylindrischen Nadel (8) erlaubt, dadurch gekennzeichnet, dass die Folien ein Paar Schweißlinien aufweisen, die Zungen (7) bilden, die von der Öffnung ausgehen und axial und symmetrisch in den Innenraum des Beutels (1) eindringen und dabei zum Innern desselben konvergieren, wobei ihre freien Enden in einem Wert "e" beabstandet sind, der etwa gleich πd/2 entspricht, wobei "d" der Wert des Durchmessers der Nadel (8) ist, so dass die Nadel beim Befüllen zwischen den Zungen (7) verläuft, wobei diese eine Abstreichfunktion der Nadel bei ihrem Herausziehen haben.
- Einheit nach Anspruch 1, dadurch gekennzeichnet, dass die zwei Schweißlinien (7) konvergieren, indem sie einen Winkel an der Spitze bilden, dessen Wert α zwischen 20 und 60° inklusive und in vorteilhafter Weise zirka 45° beträgt.
- Einheit nach Anspruch 1 oder Anspruch 2, dadurch gekennzeichnet, dass ihre Befüllungsöffnung (4) eine nach außerhalb des Beutels zeigenden Mündungszone (6) mit der konstanten Breite "a" aufweist, die etwas größer als der Abstandswert "e" der freien Enden der Schweißlinien (7) ist.
- Einheit nach Anspruch 3, dadurch gekennzeichnet, dass die Mündungszone (6) auf jeder Seite von einem geschweißten Bereich (12a, 12b) begrenzt ist, der jeweils von einer Öffnung (3, 3') durchquert ist, in welche beim Befüllen des Beutels (1) ein Rückhaltefinger (R, R') eingreifen kann.
- Einheit nach einem der Ansprüche 1 bis 4, dadurch gekennzeichnet, dass die zwei Schweißlinien (7) ein beispielsweise in Form einer Wulst (71) verstärktes Ende aufweisen.
- Einheit nach einem der Ansprüche 1 bis 5, dadurch gekennzeichnet, dass das entgegengesetzte Ende des Beutels (1) mit einer integrierten Kanüle (2) ausgestattet ist, die bestimmt ist, für das Entleeren des Beutels benutzt zu werden.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PL09178192T PL2196170T3 (pl) | 2008-12-15 | 2009-12-07 | Woreczek i taśma woreczków do kondycjonowania ciekłej substancji biologicznej, takiej jak nasienie zwierzęce |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0858587A FR2939774B1 (fr) | 2008-12-15 | 2008-12-15 | Sachet et bandes de sachet pour le conditionnement d'une substance biologique liquide, telle que de la semence animale. |
Publications (2)
Publication Number | Publication Date |
---|---|
EP2196170A1 EP2196170A1 (de) | 2010-06-16 |
EP2196170B1 true EP2196170B1 (de) | 2016-07-27 |
Family
ID=40941844
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP09178192.2A Active EP2196170B1 (de) | 2008-12-15 | 2009-12-07 | Beutel und Beutelverbund für die Verpackung einer flüssigen biologischen Substanz, wie beispielsweise Tiersamen |
Country Status (6)
Country | Link |
---|---|
US (1) | US20100150480A1 (de) |
EP (1) | EP2196170B1 (de) |
DK (1) | DK2196170T3 (de) |
ES (1) | ES2597440T3 (de) |
FR (1) | FR2939774B1 (de) |
PL (1) | PL2196170T3 (de) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9539158B2 (en) | 2013-06-19 | 2017-01-10 | American Innotek, Inc. | Liquid sequestration bag with pinch closure |
FR3027794B1 (fr) * | 2014-11-04 | 2016-12-30 | Imv Tech | Sachet de conditionnement de semence animale diluee convenant pour l'insemination artificielle, en particulier des especes porcines ; et systeme le comportant |
CN113288802B (zh) * | 2021-05-07 | 2022-08-05 | 闫一娇 | 营养液供给装置 |
Family Cites Families (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2349962A (en) * | 1942-02-12 | 1944-05-30 | Griffiths Hughes Ltd E | Container |
US2566632A (en) * | 1949-08-15 | 1951-09-04 | George J Propp | Artificial insemination device |
US2804257A (en) * | 1953-08-27 | 1957-08-27 | Dreyer Andre | Impervious container for liquid or gaseous fluids |
US3112047A (en) * | 1960-11-01 | 1963-11-26 | Cherry Burrell Corp | Liquid-tight container |
US3263903A (en) * | 1964-05-21 | 1966-08-02 | Waller Lindquist Inc | Valved container |
US3340671A (en) * | 1964-08-10 | 1967-09-12 | Carnation Co | Method of filling containers under aseptic conditions |
US3424218A (en) * | 1966-12-07 | 1969-01-28 | Garrett Corp | Medical material container |
FR2225351B1 (de) * | 1973-04-10 | 1978-10-27 | Thimonnier & Cie | |
US4265279A (en) * | 1979-08-06 | 1981-05-05 | Weikert Roy J | Package for maintaining asepsis of a sterile web of bags and method of using |
US4641362A (en) * | 1984-10-25 | 1987-02-03 | C. Muller & Associates, Inc. | Protective dispensing assembly for ultrapure liquids |
US4686814A (en) * | 1985-06-03 | 1987-08-18 | Yanase Waitch K.K. | Bag for containing flowable foodstuff |
DK152644B (da) * | 1986-04-22 | 1988-04-05 | Lindknud Plast As | Foliepose med ventil |
US5354132A (en) * | 1987-01-14 | 1994-10-11 | American Innotek, Inc. | Fluid containment bag |
US4828187A (en) * | 1987-07-06 | 1989-05-09 | Aaxon Industrial, Inc. | Particulate separation chamber and bag disposal means in a negative pressure system for collection of hazardous material |
FR2617864B1 (fr) * | 1987-07-10 | 1990-08-17 | Instr Medecine Veterinaire | Receptacle de confinement d'un liquide biologique |
US4825915A (en) * | 1987-11-17 | 1989-05-02 | Bergen Hess | Funnel construction system |
US4974732A (en) * | 1990-02-02 | 1990-12-04 | S. C. Johnson & Son, Inc. | Sealed pouch having tear-open spout |
ES2065179T3 (es) * | 1991-03-05 | 1995-02-01 | Schur Consumer Prod | Bolsa de molde refrigerante. |
US5391163A (en) * | 1992-01-31 | 1995-02-21 | Inpaco Corporation | Pouch for administering medical fluids |
CA2159583A1 (en) * | 1993-03-29 | 1994-10-13 | Jorgen Hyldgaard | A bag or pouch for containing a fluid |
FR2728456B1 (fr) * | 1994-12-23 | 1997-03-21 | Instr Medecine Veterinaire | Machine de fabrication de doses pretes a l'emploi, de semence animale, et dose de semence realisee par cette machine |
US5655653A (en) * | 1995-07-11 | 1997-08-12 | Minnesota Mining And Manufacturing Company | Pouch for orthodontic appliance |
US6050935A (en) * | 1997-05-09 | 2000-04-18 | Biofertec | Container assembly for intravaginal fertilization and culture and embryo transfer and method of intravaginal fertilization and culture employing such a container |
US6149579A (en) * | 1998-03-23 | 2000-11-21 | Lee; Won Ku | Semen storage container and its stopper |
US6551819B1 (en) * | 2000-06-29 | 2003-04-22 | Minitube Of America, Inc. | Container for semen and other biological liquids |
FR2813784B1 (fr) * | 2000-09-13 | 2003-03-07 | Pascal Lecointe | Sachet de conditionnement de substance, a canule integree et bande constituee de tels sachets |
US20020043051A1 (en) * | 2000-10-17 | 2002-04-18 | Gambro, Inc | Container and method of sealing |
FR2823435B1 (fr) * | 2001-04-11 | 2004-06-11 | Imv Technologies | Sachet de conditionnement de semence animale et de traitement uterin |
US20040161177A1 (en) * | 2003-02-14 | 2004-08-19 | N'dia Franck-Phillippe | Easily opened fluid pouch |
US8025855B2 (en) * | 2008-07-25 | 2011-09-27 | Continental Plastic Corp. | Semen container with specialized tip |
-
2008
- 2008-12-15 FR FR0858587A patent/FR2939774B1/fr active Active
-
2009
- 2009-12-07 DK DK09178192.2T patent/DK2196170T3/en active
- 2009-12-07 EP EP09178192.2A patent/EP2196170B1/de active Active
- 2009-12-07 PL PL09178192T patent/PL2196170T3/pl unknown
- 2009-12-07 ES ES09178192.2T patent/ES2597440T3/es active Active
- 2009-12-15 US US12/653,551 patent/US20100150480A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
US20100150480A1 (en) | 2010-06-17 |
EP2196170A1 (de) | 2010-06-16 |
FR2939774B1 (fr) | 2013-07-05 |
PL2196170T3 (pl) | 2017-05-31 |
DK2196170T3 (en) | 2016-10-10 |
FR2939774A1 (fr) | 2010-06-18 |
ES2597440T3 (es) | 2017-01-18 |
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