EP2182872A1 - Système pour traiter des régions riches en lipides - Google Patents
Système pour traiter des régions riches en lipidesInfo
- Publication number
- EP2182872A1 EP2182872A1 EP07800113A EP07800113A EP2182872A1 EP 2182872 A1 EP2182872 A1 EP 2182872A1 EP 07800113 A EP07800113 A EP 07800113A EP 07800113 A EP07800113 A EP 07800113A EP 2182872 A1 EP2182872 A1 EP 2182872A1
- Authority
- EP
- European Patent Office
- Prior art keywords
- protection device
- applicator
- patient protection
- temperature
- rich region
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
- A61F7/10—Cooling bags, e.g. ice-bags
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/02—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B2017/00017—Electrical control of surgical instruments
- A61B2017/00022—Sensing or detecting at the treatment site
- A61B2017/00084—Temperature
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B2017/00017—Electrical control of surgical instruments
- A61B2017/00132—Setting operation time of a device
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00988—Means for storing information, e.g. calibration constants, or for preventing excessive use, e.g. usage, service life counter
Definitions
- Excess body fat, or adipose tissue can detract from personal appearance and athletic performance.
- Excess adipose tissue may be present in various locations of the body, including, for example, the thigh, buttocks, abdomen, knees, back, face, arms, and other areas.
- excess adipose tissue is thought to magnify the unattractive appearance of cellulite, which forms when subcutaneous fat protrudes into the dermis and creates dimples where the skin is attached to underlying structural fibrous strands.
- Cellulite and excessive amounts of adipose tissue are often considered to be unappealing.
- significant health risks may be associated with higher amounts of excess body fat. An effective way of controlling or removing excess body fat therefore is needed.
- Liposuction is a method for selectively removing adipose tissue to "sculpt" a person's body. Liposuction typically is performed by plastic surgeons or dermatologists using specialized surgical equipment that invasively removes subcutaneous adipose tissue via suction.
- liposuction is a surgical procedure, and the recovery may be painful and lengthy.
- the procedure typically requires the injection of tumescent anesthetics, which is often
- WO00/LEGAL13464640.2 associated temporary bruising. Liposuction can also have serious and occasionally even fatal complications. In addition, the cost for liposuction is usually substantial. Other emerging techniques for removal of subcutaneous adipose tissue include mesotherapy, laser-assisted liposuction, and high intensity focused ultrasound.
- Conventional non-invasive treatments for removing excess body fat typically include topical agents, weight-loss drugs, regular exercise, dieting, or a combination of these treatments.
- topical agents such as topical agents, weight-loss drugs, regular exercise, dieting, or a combination of these treatments.
- weight-loss drugs or topical agents are not an option when they cause an allergic or negative reaction.
- fat loss in selective areas of a person's body cannot be achieved using general or systemic weight-loss methods.
- Non-invasive treatment methods include applying heat to a zone of subcutaneous lipid-rich cells.
- U.S. Patent No. 5,948,011 discloses altering subcutaneous body fat and/or collagen by heating the subcutaneous fat layer with radiant energy while cooling the surface of the skin. The applied heat denatures fibrous septae made of collagen tissue and may destroy fat cells below the skin, and the cooling protects the epidermis from thermal damage. This method is less invasive than liposuction, but it still may cause thermal damage to adjacent tissue, and can also be painful and unpredictable.
- Figure 1 is an isometric view of an embodiment of a system for treating subcutaneous lipid-rich regions of a subject.
- Figure 2 is a block diagram illustrating an environment in which the system may operate in some embodiments.
- Figure 3 is a block diagram illustrating subcomponents of components of the system in various embodiments.
- Figure 4 is a block diagram illustrating data structures employed by the system in various embodiments.
- Figure 5 is a flow diagram illustrating a control_applicator method invoked by the system in some embodiments.
- Figure 6 is a flow diagram illustrating an authenticate routine invoked by the system in some embodiments.
- Figure 7 is a flow diagram illustrating a validate_disposable_sleeve routine invoked by the system in some embodiments.
- Figure 8 is a flow diagram illustrating an update routine invoked by the system in some embodiments.
- Figure 9 is a front isometric view of an embodiment of an applicator.
- Figures 10A-10B are user interface diagrams illustrating aspects of user interfaces provided by the system in various embodiments.
- a system for treating a subject's subcutaneous adipose tissue, such as by cooling it.
- subcutaneous tissue means lying beneath the dermis and includes subcutaneous fat, or adipose tissue, which primarily is composed of lipid-rich cells, or adipocytes.
- the cooling system includes a controller, a computing device, a data acquisition device, a chiller, and one or more applicators. The cooling system can employ these components in various embodiments to receive a selection of a treatment profile and apply the selected treatment using an applicator.
- An applicator is a component of the cooling system that cools a region of a subject, such as a human or animal subject.
- Various types of applicators can be applied during treatment, such as a massage or vibrating applicator, a vacuum applicator, a belt applicator, and so forth.
- Each applicator may be designed to treat identified portions of the subject's body, such as chin, cheeks, arms, pectoral areas, thighs, calves, buttocks, and so forth.
- the massage or vibrating applicator can be applied at the pectoral region
- the vacuum applicator may be applied at the cheek region
- the belt applicator can be applied around the thigh region.
- One type of applicator is described by commonly assigned U.S. Patent App. Ser. No. 11/528,189, entitled “Cooling Devices With Flexible Sensors,” which was filed on September 26, 2006, and is incorporated herein in its entirety by reference.
- a patient protection device is an apparatus that prevents the applicator from directly contacting a subject's skin and thereby can reduce the likelihood of cross-infection between subjects and cleaning requirements of the applicator.
- the patient protection device e.g., sleeve
- the sleeve can be reused or can enforce single use electrically, mechanically, or electromechanically.
- the sleeve can include a sterility barrier, various electronics, sensors, memory, and/or security components.
- the sleeve may also contain various storage and communications devices, such as a radio frequency identification (RFID) component.
- RFID radio frequency identification
- a sleeve may be specifically designed for use with a limited set of applicators. When the sleeve is applied to an applicator, memory included with the sleeve may be accessible by the controller.
- the memory can include one or more treatment profiles. Each treatment profile can be used.
- WO00/LEGAL13464640.2 -4- include one or more segments and each segment can include a specified duration, a target temperature, and control parameters for features such as vibration, massage, vacuum, and other treatment modes.
- the controller can cause the applicator to cycle through each segment of the treatment profile.
- the applicator applies power to one or more cooling devices, such as a thermoelectric cooler, to begin a cooling cycle and, for example activate features or modes such as vibration, massage, vacuum, etc.
- the controller determines whether a temperature that is sufficiently close to the target temperature has been reached.
- the cooled region of the body e.g., adipose tissue
- region of the body may be close but not equal to the target temperature, e.g., because of the body's natural heating and cooling tendency.
- the system may attempt to heat or cool to the target temperature, a sensor may measure a sufficiently close temperature. If the target temperature has not been reached, power may be increased or decreased, as needed, to maintain the target temperature or "set-point.” When the indicated duration expires, the controller may apply the temperature and duration indicated in the next treatment profile segment.
- temperature can be controlled using a variable other than, or in addition to, power output.
- the controller controls the temperature applied by the applicator, it employs a chiller.
- a chiller is a device that, based on variable power input, can increase or decrease the temperature at a connected thermoelectric cooler that is attached to the applicator.
- the applicator can have one or more attached cooling devices, such as thermoelectric coolers.
- the chillers can employ a number of cooling technologies (“cooler") including, for example, thermoelectric coolers, recirculating chilled fluid, vapor compression elements, or phase change cryogenic devices.
- cooler including, for example, thermoelectric coolers, recirculating chilled fluid, vapor compression elements, or phase change cryogenic devices.
- a data acquisition device component of the cooling system can collect data from the controller, chiller, applicator, and other components.
- the controller can collect data from the controller, chiller, applicator, and other components.
- the controller can collect data from the controller, chiller, applicator, and other components.
- the controller can collect data from the controller, chiller, applicator, and other components.
- WO00/LEGAL13464640.2 -5- data acquisition device can collect information such as how much power is being applied, the temperature at each cooler, the temperature at the subject's skin, the status of the chiller, controller, or applicator, and so forth.
- the data acquisition device component can provide the collected information to a computing device.
- the computing device can receive the information the data acquisition device component collects, collect other information, such as from the sleeve or from user input, and take various actions, such as by commanding the controller.
- the computing device can cause the controller to increase or decrease the temperature at various coolers based on the indicated skin temperature, selected treatment profile, and so forth.
- the computing device or the applicator can provide various user interfaces, such as to begin treatment; display treatment profiles or their segments, current status, or terminate treatment; provide alarms or other notifications relating to abnormal or unexpected conditions; and so forth. These user interfaces can be provided to operators of the cooling system or to subjects.
- the cooling system will now be described with reference to the Figures.
- FIG. 1 is an isometric view of an embodiment of a cooling system 100 for removing heat from subcutaneous lipid-rich regions of a subject 101.
- the system 100 can include a cooling device 104 including an applicator 105; the cooling device 104 can be placed at an abdominal area 102 of the subject 101 or at any another suitable area for removing heat from a subcutaneous lipid-rich region of the subject 101.
- Various shapes and sizes of cooling devices 104 and applicators 105 can be applied to different regions.
- the cooling system 100 can further include a chiller 106 and supply and return fluid lines 108a-b between the cooling device 104 and the chiller 106.
- the chiller 106 can remove heat from a circulating coolant to a heat sink and provide a chilled coolant to the cooling device 104 via the fluid lines 108a-b.
- the circulating coolant include water, glycol, synthetic heat transfer fluid, oil, a refrigerant, and/or any other suitable heat conducting fluid.
- the fluid lines 108a-b can be hoses or other conduits constructed from polyethylene, polyvinyl chloride, polyurethane, and/or other materials that can accommodate the particular circulating
- the chiller 106 can be a refrigeration unit, a cooling tower, a thermoelectric chiller, or any other device capable of removing heat from a coolant.
- the cooling device 104 includes the applicator 105 and one or more heat exchanging units.
- the heat exchanging unit can be a Peltier-type thermoelectric element, and the cooling device 104 can have multiple individually controlled heat exchanging units to create a custom spatial cooling profile.
- the system 100 can further include a power supply 110 and a processing unit 114 operatively coupled to the cooling device 104 and the applicator 105.
- the power supply 110 can provide a direct current voltage to the thermoelectric cooling device 104 and/or the applicator 105 to remove heat from the subject 101.
- the controller 114 can monitor process parameters via sensors (not shown) placed proximate to the cooling device 104 via control line 116 to adjust the heat removal rate based on the process parameters.
- the controller 114 can further monitor process parameters to adjust applicator 105 based on treatment parameters, such as treatment parameters defined in a treatment profile.
- the controller 114 can exchange data with the applicator via line 112 or via wireless communication.
- the controller 114 can include any processor, Programmable Logic Controller, Distributed Control System, and the like.
- the controller 114 can receive data from an input device 118, transmit data to an output device 120, and/or exchange data with a control panel 122.
- the input device 118 can include a keyboard, a mouse, a stylus, a touch screen, a push button, a switch, a potentiometer, a scanner, or any other device suitable for accepting user input.
- the output device 120 can include a display screen, a printer, a medium reader, an audio device, or any other device suitable for providing user feedback.
- the control panel 122 can include indicator lights, numerical displays, and audio devices.
- the cooling device 104 can include the input device 118, output device 120, and/or control panel 122.
- Figure 1 illustrates, the controller 114, power supply 110, control panel 122, chiller 106, input device 118, and output device 120 can be carried by a rack 124 with wheels 126 for portability.
- the controller 114 can be contained on the cooling device 104 or on the applicator 105.
- the various components can be fixedly installed at a treatment site.
- WO00/LEGAL13464640.2 -7- Although a noninvasive applicator is illustrated and discussed herein, minimally invasive applicators may also be employed. In such a case, the applicator and sleeve may be integrated.
- a cryoprobe that may be inserted directly into the subcutaneous adipose tissue to cool or freeze the tissue is an example of such a minimally invasive applicator.
- Cryoprobes manufactured by, e.g., Endocare, Inc., of Irvine, California are suitable for such applications.
- FIG. 2 is a block diagram illustrating an environment in which the cooling system may operate in some embodiments.
- the environment 200 includes a power supply 202 and an isolation transformer 204.
- the power supply 202 can be any ordinary type of power supply, such as alternating current or direct current.
- the isolation transformer 204 can be a medical grade transformer that isolates the subject from power fluctuations and problems, such as leakage current, voltage spikes or dips, and so forth.
- the environment 200 also includes a computing device 206 and a user interface 208.
- the computing device 206 can be integrated with a controller 210 or can be a separate unit.
- the computing device 206 can be a single board computer that is adapted for use within a housing of the controller 210.
- the controller 210 can be integrated with the applicator 216.
- the user interface 208 can include various input devices for collecting input from a user, such as an operator of the cooling system, and can also include various output devices, such as for providing information to the operator, subject, and so forth.
- the computing device can be connected to the controller to receive input from the controller and provide commands to the controller.
- Various components of the cooling system may connect to other components via wired or wireless connections, such as Ethernet, serial (e.g., RS-232 or universal serial bus) connections, parallel connections, IEEE 802.11 , IEEE 802.15, IEEE 802.16, "WIMAX,” IEEE 1394, infrared, Bluetooth, and so forth.
- the computing device can also connect to a data acquisition device 212.
- the data acquisition device 212 can acquire data from various components, such as the controller 210, chiller 214, and applicator 216, and provide the retrieved data to other components, such as to the computing device 206.
- the data acquisition device can be incorporated into the controller or applicator.
- the computing device 206 can employ the data it receives from the data acquisition device 212, such as to command the controller 210 to take various actions. As an example, the computing device 206 may command the controller 210 to change operating parameters at the applicator. As another example, detecting that the skin temperature of the subject is too low, the computing device 206 can cause the applicator 216 to increase the temperature via the controller 210. Other connections between components may also exist in various embodiments, but are not illustrated. As an example, the controller 210 can connect to the chiller 214, such as to command the chiller. Alternatively, the connections can be indirect.
- the controller 210 can command the chiller 214 via the applicator 216.
- the applicator can connect to one or more heat exchanging units 218a and 218b, such as thermoelectric heat exchanging units.
- the heat exchanging units 218a-b may be housed in a sleeve 224.
- the applicator 216 and heat exchanging units 218a-b may together be housed in a sleeve 224.
- the applicator 216 can include thermoelectric heat exchanging units, heat exchanging unit temperature sensors, chemical sensors, electrical sensors, moisture sensors, skin temperature sensors, vacuum devices, and vibration or massage devices.
- the applicator can receive commands from a controller 210 to control temperature, vacuum, vibration, and so forth. It may also provide temperature or operating information to the controller 210 or computing device 206, such as via the data acquisition device 212.
- the sleeve 224 can be disposed and replaced, such as after every use, every subject, time period, number of uses, and so forth.
- Information on the application of a sleeve to a patient or subject can be stored in a memory associated with the sleeve.
- various components of the cooling system such as sleeves, can employ a secure memory, such as "CRYPTOMEMORY.”
- Secure memory devices such as CRYPTOMEMORY devices produced by ATMEL Corp., of San Jose, California, enable memory access through dynamic symmetric mutual authentication, data encryption, and other software- based or firmware-based security techniques. The contents of this memory cannot be accessed by devices or software that do not conform to the security measures.
- the secure memory may employ tamper detection circuitry to also prevent hardware attacks.
- the secure memory can be connected to flex circuits.
- a flex circuit is a printed circuit board that is pliable and that may be integrated with some types of applicators or sleeves, such as sleeve 224.
- Some components may also employ secure enclosures in various embodiments.
- the controller 210 and/or computing device 206 can be housed in a secure enclosure.
- the secure enclosure may include features to deter physical access to the components of the system, such as switches to detect intrusion.
- the controller 210 and/or computing device 206 can include hardware and firmware to respond to detected intrusions, such as by disabling the ability to perform treatments, erasing memory, and so forth.
- the computing device 206 may connect to network resources, such as other computers 222a-c. As examples, the computing device 206 may connect to a server 222a to upload data logs, subject information, use information, and so forth. The computing device 206 may also connect to a server 222b to download updates to software, lists of applicators or sleeves that should be disabled, and so forth. As an example, once a sleeve 224 has passed its expiry date or its lifespan has otherwise been determined to be expired, the computing device 206 may upload an identifier associated with the sleeve to a server for download by other computing devices so that the expired sleeve cannot be used with other cooling systems. The computing device 206 may connect to network resources via a network 220, such as the Internet or an intranet.
- a network 220 such as the Internet or an intranet.
- FIG. 3 is a block diagram illustrating subcomponents of components of the cooling facility in various embodiments.
- Components of the cooling facility can include a computing environment 300.
- the computing environment 300 can include input lines 302a, 302b, and 302c. In various embodiments, multiple input lines may be employed.
- the computing environment 300 can also provide output lines 304a, 304b, and 304c. In various embodiments, multiple output lines may be provided.
- the computing environment may also include a processor 306, memory 308, input handler 310, output handler 312, and bus 314.
- the processor 306 can be a standard central processing unit or a security processor.
- Security processors can be special-purpose processors (e.g., reduced instruction set processor) that can withstand sophisticated attacks that attempt to extract data or programming logic.
- the security processors may not have debugging pins that enable an external debugger to monitor the security processor's execution or registers.
- the cooling system may employ a secure field programmable gate array.
- the memory 308 can be standard memory, secure memory, or a combination of both memory types.
- the cooling system can ensure that data and instructions are both highly secure and sensitive operations such as decryption are shielded from observation.
- the input handler 310 and output handler 312 retrieve input from lines 302a-c and provide output to lines 304a-c, such as via bus 314.
- the cooling system can employ data structures that are stored in memory, such as in secure memory.
- the data structures enable the cooling system to provide treatment choices, ensure system integrity, and protect subject safety and privacy.
- FIG. 4 is a block diagram illustrating data structures employed by the cooling system in various embodiments.
- the illustrated data structures 400 can be stored in memory associated with various components of the cooling system, such as secure memory associated with sleeves. Some of the data structures 400 may be indicated for read-only access, write-only access, or read/write access. The type of access can be enforced via a combination of hardware and/or software. As an
- the data structures 400 can include an identifier ("ID") block 402, profiles block 420, and use block 450. Each of these blocks will now be described.
- ID identifier
- the ID block 402 can include fields for a sleeve type 404, manufacturing date 406, serial number 408, and one or more limit type 410, limit value 412 pairs. These fields are generally indicated for read-only access.
- the sleeve type field 404 can store the type of sleeve, such as whether or not the sleeve is disposable, the types of applicators the sleeve is compatible with, the manufacturer of the sleeve, and so forth.
- the manufacturing date field 406 can store the date on which the sleeve was manufactured or distributed.
- the serial number field 408 can store a unique sleeve identifier.
- the limit type field 410 stores the type of limit that is imposed on the sleeve.
- Limit types can include use counts, dates, times, and so forth.
- the cooling system includes flexibility in defining limit types. As an example, one sleeve type may have use-based limits whereas another sleeve type may have time-based limits, and a third sleeve type may include both time- and use-based limits.
- the limit value field 412 may store the number of times that the corresponding sleeve can be used. As an example, when the value stored by the limit type field 410 indicates that the limit is based on use, the limit value field 412 may indicate that the sleeve expires after one use.
- the limit value field 412 may store the date or time duration after which the sleeve expires.
- the limit value field 412 may store a specific date after which the sleeve cannot be used, such as the date at which the shelf life of a sterile sleeve expires.
- the limit type field 410 indicates that the limit is based on a time duration
- WO00/LEGAL13464640.2 -12- value field 412 may store a time duration after which the sleeve cannot be used. The time duration may be measured from the time the sleeve is first used.
- the profiles block 420 stores information pertaining to treatment profiles. This includes a number of profiles field 422 for storing the number of profiles that are stored in the profiles block. Each profile indicates a name and has a number of segments, which are identified in the profiles block, such as in fields 424, 426, 436, and 438. Each profile also provides treatment-related information for each segment. As an example, segments 434 provide treatment-related information associated to the first profile identified in the illustrated profiles block. The treatment-related information includes ramp time 428, dwell time 430, and target temperature 432.
- the ramp time is the amount of time, such as in seconds, that the cooling system is to take to cool (or heat) a heat exchanging unit associated with an applicator so as to arrive at the target temperature 432 at the end of the specified amount of time.
- Various curves can be used to change the temperature, such as linear, asymptotic, geometric, and so forth.
- the dwell time 430 indicates the amount of time, such as in seconds, that the heat exchanging unit is to apply the target temperature 432.
- the number of segments for each profile is stored in the number of segments fields associated with each profile, such as fields 426 and 428.
- the name fields 424 and 436 can store names associated with each profile. These names can be retrieved and displayed in a user interface that an operator of the cooling system can use to select a profile.
- Each segment of a profile can identify parameters for one or more heat exchanging units associated with an applicator.
- blocks 440- 446 identify parameters that can be used to control heat exchanging units independently. Thus, for example, when an applicator with multiple heat exchanging units is employed, different areas of the subject's body proximate to each heat exchanging unit can receive different cooling treatments.
- the profiles block may also include additional fields, such as to indicate whether a vacuum device, vibrator device, or massage device should be turned on or off, the vacuum force or vibration frequency, and so forth.
- the profiles block 420 may also be indicated for read-only access.
- the use block 450 stores information relating to use of a component, such as use of the sleeve associated with the memory storing the use block 450.
- the use block 450 can include a use counter field 452, a use identifier field 456, a
- the use counter field 452 stores a count of the number of times the sleeve has been used during application of a treatment.
- a record can be stored in the use block for each use.
- the use identifier field 456 identifies the record.
- the use start field 458 stores the time at which treatment started and the use stop field 460 stores the time at which treatment stopped.
- the identifier (“ID") field 462 stores an identifier, such as an identifier of the applicator and/or controller component that was used during treatment, a patient identifier, and so forth.
- the log field 464 stores a log of operational characteristics, such as errors, profiles applied, and information from various sensors, such as temperature sensors.
- the cooling system may transmit information contained in the use block, such as to a distributor or manufacturer for tracking or troubleshooting purposes. Fields in the use block can be indicated for read/write access.
- additional data structures can be added, such as to store calibration data, diagnostic data, test data, security data (e.g., to store security keys), executable code, and so forth.
- the cooling system invokes a number of routines. While some of the routines are described herein, one skilled in the art is capable of identifying other routines the cooling system could perform. Moreover, the routines described herein can be altered in various ways. As examples, the order of illustrated logic may be rearranged; substeps may be performed in parallel, illustrated logic may be omitted, other logic may be included, etc.
- FIG. 5 is a flow diagram illustrating a control_applicator routine invoked by the cooling system in some embodiments.
- the routine can be invoked by a computing device, such as a single board computer associated with a controller, to control an applicator.
- the computing device may invoke the control applicator routine 500 after an operator selects a treatment profile from a list of treatment profiles.
- the routine 500 begins at block 502.
- the routine receives duration information, such as ramp time and dwell time. This information can be retrieved from a selected treatment profile.
- the routine receives a target temperature indication.
- WO00/LEGAL13464640.2 -14- target temperature is the temperature identified in the first segment of the selected treatment profile.
- the routine causes the applicator to cycle through each segment of the selected treatment profile.
- the routine determines ramp characteristics.
- Ramp characteristics determine the slope of the increase or decrease in temperature as a function of time.
- Ramp characteristics can be implemented using various control schemes, such as open loop, bang-bang overshoot, proportional, proportional integral, proportional integral derivative, and others.
- the cooling system sends a constant amount of power and does not adjust power based on temperature feedback from sensors.
- the bang-bang overshoot control scheme the cooling system applies power and when it senses via a temperature sensor that it has passed the target temperature, it applies more or less cooling, as appropriate.
- the cooling system compares the target temperature with the actual temperature (e.g., at the applicator) and applies a transfer function (e.g., to the power) to correct the temperature.
- the transfer function can be proportional to the amount of difference between the target and actual temperatures.
- prior differences between the target and actual temperatures are additionally incorporated when attempting to achieve the target temperature.
- proportional integral derivative control scheme the first derivative of the prior differences is used to reduce the possibility of overshooting the target temperature and react to system perturbations in a more stable manner.
- the routine communicates parameters, such as ramp time, dwell time, target temperature, and ramp characteristics, to the controller so that the controller can effectuate the segment of the treatment profile that is presently being applied.
- the routine reads temperature, power, and other data from the controller and/or the data acquisition device ("DAQ").
- the routine records the read data in a log, such as in a log that is stored in memory or a database. The data that is stored in the log can be transmitted, such as to a server or other computing device via a network or other connection.
- the routine determines whether there is a significant difference between the temperatures of the subject's skin and one or more heat exchanging units associated with the controlled applicator.
- the significance of the temperature difference can be specified by an operator, by a treatment profile, and so forth. The temperature difference can also be tuned, such as based on the sensitivity of the subject. If the temperature difference is significant, the routine continues at block 520. Otherwise, the routine continues at decision block 518.
- the routine takes corrective actions. As an example, the routine may cause the applicator to raise the temperature of the heat exchanging units having a significant temperature difference, alert the operator to the condition, terminate the treatment, and so forth. The routine may then continue at block 522, where it returns.
- the routine determines whether the duration, e.g., the dwell time, has expired. If the duration has expired, the routine continues at block 522, where it returns. Otherwise, the routine continues at block 510. In various embodiments, the routine may be invoked for each segment of a treatment profile.
- the cooling system can update various data structures when a treatment is applied.
- the updates can occur before treatment begins or after it ends. These updates can include use counts, treatment profiles applied, and times treatment started or stopped.
- the updates can also include records of treatment attributes, such as temperatures, error conditions, and so forth.
- the updates can be made in secure memory, such as secure memory associated with sleeves, controllers, computing devices, or other components.
- FIG. 6 is a flow diagram illustrating an authenticate routine invoked by the cooling system in some embodiments.
- the cooling system can invoke the authenticate routine 600 when it powers on or when it detects that a component has connected to the cooling system.
- the cooling system may invoke the authenticate routine 600 when a sleeve is connected to the cooling system.
- the routine 600 authenticates each component that is connected to the cooling system.
- the routine 600 begins at block 602.
- the routine detects a power on condition or connection of a component.
- the cooling system may invoke the routine 600 when an applicator, sleeve, or other component is connected to the cooling system.
- the routine identifies each component that is connected to the cooling system, spanning the entire chain from the sleeve to the computing device that executes the routine.
- the routine may identify all components in the chain even though the component that invokes the routine may be within the chain or not even in the chain.
- the routine authenticates all components in the chain of components.
- the routine may authenticate all components in the chain of components when the routine detects a power on condition, and may authenticate only the newly connected component when the routine detects the connection of a component.
- the routine may authenticate all components when the cooling system is first powered on and then may authenticate only newly connected sleeves when sleeves are replaced between treatments.
- the logic of blocks 606 may be skipped when the routine detects connection of a newly added component.
- the routine may employ various mechanisms for authenticating components. Although some mechanisms are identified herein, one skilled in the art would recognize that various mechanisms exist for authenticating components. As an example, one such mechanism is a concept known as trusted computing. When using the trusted computing concept, transactions between every component are secured, such as by using encryption, digital signatures, digital certificates, or other security techniques.
- the component When a component connects to the cooling system, the component may be queried (e.g., challenged) for its authentication credentials, such as a digital certificate. The component could then provide its authentication credentials in response to the query. Another component that sent the query can then verify the authentication credentials, such as by verifying a one-way hash value, private or public key, or other data that can be used to authenticate the component.
- the authentication credentials or authentication function can be stored in a secure memory that is associated with the component that is to be authenticated.
- a querying component can provide a key to a queried component and the queried component can respond by employing an authentication function, such
- the routine determines whether a component cannot be authenticated. As an example, the routine may detect whether any component in the chain of components could not be authenticated. If at least one of the components in the chain of components cannot be authenticated, the routine continues at block 612. Otherwise, the routine continues at block 616.
- the routine stores an indication in a log that the component(s) could not be authenticated and can report an error to the operator of the cooling system.
- the routine disables treatments so that the unauthenticated component cannot be used with the cooling system.
- the cooling system can continue treatments. The routine then continues at block 618, where it returns.
- the routine enables treatments so that when a treatment is started, appropriate action can be taken by the cooling device, such as based on selected treatment profiles.
- the routine then returns at block 618.
- the cooling systems supports an authentication override feature.
- an operator may request a manufacturer or distributor of the cooling system for an authentication override key. Upon receiving this authentication override key, the operator can provide it to the cooling system. The cooling system may then operate with unauthenticated components for a defined period of time, such as 30 days. After expiry of this period of time, the cooling system may need to receive code updates or other maintenance to again be able to enable the authentication override feature. In some embodiments, the operator may be able to override authentication a defined number of times with different authentication override keys before the cooling system is updated or
- the cooling system can ignore authentication failures of some or all components of the cooling system. As an example, an operator may need to use recently expired sleeves because new sleeves are not available. In such a case, the operator may override authentication until the new sleeves arrive.
- FIG. 7 is a flow diagram illustrating a validate_disposable_sleeve routine invoked by the cooling system in some embodiments.
- the cooling system can invoke the validate_disposable_sleeve routine 700 to validate a newly connected sleeve, such as when authenticating connected components (e.g., at block 608 of Figure 6).
- the validate_disposable_sleeve routine 700 begins at block 702.
- the routine detects the connection of a sleeve.
- the routine may receive an indication that a sleeve has been connected, such as from an applicator or a controller.
- the applicator may detect the connection of the sleeve electronically or mechanically.
- the applicator may then provide an indication that a sleeve has been connected, such as to a controller.
- the routine authenticates the remainder of the cooling system with the newly connected sleeve. Authentication of components was described above in relation to Figure 6. The routine may employ the same authentication mechanisms or a different authentication mechanism to authenticate with the sleeve.
- the routine retrieves an identification ("ID”) block and a use block that are stored in a memory, such as a secure memory, that is associated with the newly connected sleeve.
- ID an identification
- use block that are stored in a memory, such as a secure memory, that is associated with the newly connected sleeve.
- the ID and/or use blocks may be encrypted.
- the routine decrypts the ID block at block 710.
- the routine can also decrypt use blocks that are encrypted.
- Various encryption and decryption techniques are known in the art, such as encryption techniques that use public or private keys that can be symmetric or asymmetric. These encryption and decryption techniques can be applied via hardware and/or software.
- the routine verifies the validity of the newly connected sleeve.
- the routine may employ various techniques to verify the validity of the newly connected sleeve.
- the routine may ensure that the data stored in the fields of the retrieved ID block are valid, such as by verifying the stored sleeve type and serial number.
- the routine may also compare an identifier (e.g., serial number) of the sleeve to a list of sleeves that are known to be invalid or expired.
- the list of invalid sleeves may be provided by the operator of the cooling system, manufacturer of the cooling system, distributor of the cooling system, or others.
- the cooling system may update the list of invalid sleeves from time to time automatically, such as by downloading the list via a network connection.
- the list can be stored in a memory or storage device, such as in a circular buffer or a table.
- the routine can also compare the use limit data from the ID block to the use data recorded in the use block to determine if the sleeve is expired.
- FIG. 8 is a flow diagram illustrating an update routine invoked by the cooling system in some embodiments.
- the cooling system may invoke the update routine when it receives code for updating updatable code of the cooling system.
- the cooling system may receive the code via a network connection or a sleeve.
- the cooling system can apply the update.
- the update routine 800 begins at block 802.
- the routine receives a code update from a sleeve.
- the routine may receive an indication to update the code from the sleeve and may then retrieves the code via a network connection, such as from a server.
- the routine may also receive the indication to update the code from a server, an operator of the cooling system, or from other sources.
- the routine may then retrieves the code via a network connection or from another source, such as from a storage device that the cooling system connects to.
- the routine may authenticate the source of the code update before retrieving the code.
- the routine applies the code update.
- the routine can apply the code update to a computing device, a controller, an applicator, or other component of the cooling system that stores code.
- FIG. 9 is a front isometric view of an embodiment of an applicator.
- the applicator 900 includes an application portion 902 and a user interface portion 904.
- the applicator portion can include heat exchanging units, vibrators or massagers, vacuums, and connections to a controller, chiller, and other components of the cooling system. These units and lines of connection are hidden in the illustrated front isometric view.
- the user interface portion 904 can include a display panel 906, such as a touchscreen or other output device, and one or more input features, such as buttons or dials 908.
- applicators have different sizes and shapes than the illustrated applicator 900.
- applicators can take the form of belts, handheld devices, and other devices of various sizes and shapes.
- the user interface associated with an applicator can include various input and output devices, such as buttons, knobs, styluses, trackballs, microphones, touchscreens, liquid crystal displays, light emitting diode displays, lights, speakers, earphones, headsets, and the like.
- FIGs 10A-10B are user interface diagrams illustrating aspects of user interfaces provided by the cooling system in various embodiments.
- the cooling system can display a list of treatment profiles 1004, test routines, or debugging/troubleshooting routines in a display 1002.
- the display 1002 can be displayed in a display panel 906 associated with an applicator (illustrated in Figure 9) or on some other output device, such as an output device 120 (illustrated in Figure 1).
- the list of treatment profiles 1004 can be retrieved from memory associated with a sleeve.
- the operator of the cooling device can select one of the profiles to apply during treatment. As an example, the operator can select one treatment profile for one region of the subject's body and another treatment profile for another segment of the subject's body.
- the cooling system can connect to multiple applicators in some embodiments and each applicator can be applied in parallel.
- the operator can select other attributes that can cause the selected profile to be varied, such as the subject's characteristics (e.g., sex, weight, height, etc.) or subject's goals (e.g., amount of fat removal expressed in millimeters or percentages).
- the operator can also indicate other attributes, such as the subject's pain sensitivity, total number of treatments desired, and so forth. As an example, if the subject is available for many treatments, each treatment may need less time to administer.
- the cooling system can display various information during a treatment in a display 1010.
- the display 1010 can be displayed in a display panel 906 associated with an applicator (illustrated in Figure 9) or on some other output device, such as output device 120 illustrated in Figure 1.
- the display 1010 can include a count-up timer 1012, a count-down timer 1014, target temperature 1016, actual temperature 1018, and a chart 1020.
- the count-up timer 1012 can count the elapsed time, such as the elapsed time of the treatment or the current treatment profile segment.
- the countdown timer 1014 can count the time remaining, such as the time remaining for the treatment or the current treatment profile segment.
- the target temperature 1016 can show the target temperature, such as for a selected heat exchanging unit or other portion of the applicator.
- the actual temperature 1018 can show the actual temperature at the region corresponding to the target temperature 1016 or at some other region.
- the chart 1020 can depict various information in a graphical form, such as a temperature vs. time chart.
- a marker 1022 can indicate the present time in relation to the chart so that an operator or subject can quickly see what actions the treatment profile will take or has taken. As an example, according to the illustration, the treatment profile will soon reduce the temperature for some time period and will subsequently increase the temperature.
- the cooling system can take input from other devices.
- the cooling system can receive an image, such as from an ultrasound device, and enable the operator or subject to indicate on the image how much fat should be removed.
- the controller can then determine the applicable treatment profile, such as based on the fat thickness and other attributes.
- aspects of the technology may be stored or distributed on computer- readable media, including magnetically or optically readable computer discs, hardwired or preprogrammed chips (e.g., EEPROM semiconductor chips), nanotechnology memory, biological memory, or other data storage media.
- computer implemented instructions, data structures, screen displays, and other data under aspects of the technology may be distributed over the Internet or over other networks (including wireless networks), on a propagated signal on a propagation medium (e.g., an electromagnetic wave(s), a sound wave, etc.) over a period of time, or they may be provided on any analog or digital network (packet switched, circuit switched, or other scheme).
Landscapes
- Health & Medical Sciences (AREA)
- Vascular Medicine (AREA)
- Thermal Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Physics & Mathematics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Thermotherapy And Cooling Therapy Devices (AREA)
- Surgical Instruments (AREA)
Abstract
L'invention porte sur un système de refroidissement pour éliminer de la chaleur à partir de régions riches en lipides sous-cutanés d'un sujet, telles que des tissus, des organes, des cellules, etc. Dans divers modes de réalisation, le système de refroidissement comprend un contrôleur, un dispositif de calcul, un dispositif d'acquisition de données, un refroidisseur et un ou plusieurs applicateurs. Le système de refroidissement peut employer ces composants pour recevoir une sélection d'un profil de traitement et appliquer le traitement sélectionné à l'aide d'un applicateur. Le profil de traitement peut être reçu à partir d'un manchon qui se connecte à un applicateur.
Applications Claiming Priority (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11/778,001 US20090018626A1 (en) | 2007-07-13 | 2007-07-13 | User interfaces for a system that removes heat from lipid-rich regions |
US11/777,999 US20090018625A1 (en) | 2007-07-13 | 2007-07-13 | Managing system temperature to remove heat from lipid-rich regions |
US11/777,995 US20090018624A1 (en) | 2007-07-13 | 2007-07-13 | Limiting use of disposable system patient protection devices |
US11/777,992 US8523927B2 (en) | 2007-07-13 | 2007-07-13 | System for treating lipid-rich regions |
US11/778,003 US20090018627A1 (en) | 2007-07-13 | 2007-07-13 | Secure systems for removing heat from lipid-rich regions |
PCT/US2007/075935 WO2009011708A1 (fr) | 2007-07-13 | 2007-08-14 | Système pour traiter des régions riches en lipides |
Publications (1)
Publication Number | Publication Date |
---|---|
EP2182872A1 true EP2182872A1 (fr) | 2010-05-12 |
Family
ID=39186761
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP07800113A Withdrawn EP2182872A1 (fr) | 2007-07-13 | 2007-08-14 | Système pour traiter des régions riches en lipides |
Country Status (3)
Country | Link |
---|---|
EP (1) | EP2182872A1 (fr) |
JP (1) | JP2010533054A (fr) |
WO (1) | WO2009011708A1 (fr) |
Families Citing this family (54)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP4703724B2 (ja) | 2006-04-28 | 2011-06-15 | ゼルティック エステティックス インコーポレイテッド | 皮下の脂質リッチ細胞の冷却が改善された治療装置に使用する凍結防止剤 |
US20080077201A1 (en) | 2006-09-26 | 2008-03-27 | Juniper Medical, Inc. | Cooling devices with flexible sensors |
US8192474B2 (en) | 2006-09-26 | 2012-06-05 | Zeltiq Aesthetics, Inc. | Tissue treatment methods |
US9132031B2 (en) | 2006-09-26 | 2015-09-15 | Zeltiq Aesthetics, Inc. | Cooling device having a plurality of controllable cooling elements to provide a predetermined cooling profile |
US20080287839A1 (en) | 2007-05-18 | 2008-11-20 | Juniper Medical, Inc. | Method of enhanced removal of heat from subcutaneous lipid-rich cells and treatment apparatus having an actuator |
US8523927B2 (en) | 2007-07-13 | 2013-09-03 | Zeltiq Aesthetics, Inc. | System for treating lipid-rich regions |
US8285390B2 (en) | 2007-08-21 | 2012-10-09 | Zeltiq Aesthetics, Inc. | Monitoring the cooling of subcutaneous lipid-rich cells, such as the cooling of adipose tissue |
US8603073B2 (en) | 2008-12-17 | 2013-12-10 | Zeltiq Aesthetics, Inc. | Systems and methods with interrupt/resume capabilities for treating subcutaneous lipid-rich cells |
BRPI1014623B1 (pt) | 2009-04-30 | 2020-01-07 | Zeltiq Aesthetics, Inc. | Sistema para tratamento de celulas subcutâneas ricas em lipídeos em uma área alvo |
AU2011207506A1 (en) | 2010-01-25 | 2012-08-09 | Zeltiq Aesthetics, Inc. | Home-use applicators for non-invasively removing heat from subcutaneous lipid-rich cells via phase change coolants, and associated devices, systems and methods |
US8676338B2 (en) | 2010-07-20 | 2014-03-18 | Zeltiq Aesthetics, Inc. | Combined modality treatment systems, methods and apparatus for body contouring applications |
WO2012103315A2 (fr) | 2011-01-27 | 2012-08-02 | Osa Holdings, Inc. | Appareil et méthodes de traitement de l'apnée obstructive du sommeil faisant appel à la cryolyse des tissus adipeux |
DE202012002278U1 (de) | 2012-03-08 | 2012-06-26 | Friedemann Lotsch | Gerät für die Kryolipolyse |
DE102012013534B3 (de) | 2012-07-05 | 2013-09-19 | Tobias Sokolowski | Vorrichtung für repetitive Nervenstimulation zum Abbau von Fettgewebe mittels induktiver Magnetfelder |
EP2932931B1 (fr) | 2013-02-13 | 2019-07-24 | Olympus Corporation | Système chirurgical |
US9844460B2 (en) | 2013-03-14 | 2017-12-19 | Zeltiq Aesthetics, Inc. | Treatment systems with fluid mixing systems and fluid-cooled applicators and methods of using the same |
US9545523B2 (en) | 2013-03-14 | 2017-01-17 | Zeltiq Aesthetics, Inc. | Multi-modality treatment systems, methods and apparatus for altering subcutaneous lipid-rich tissue |
ES2974899T3 (es) | 2014-01-31 | 2024-07-02 | Zeltiq Aesthetics Inc | Composiciones y sistemas de tratamiento para el enfriamiento mejorado de tejido rico en lípidos |
US10675176B1 (en) | 2014-03-19 | 2020-06-09 | Zeltiq Aesthetics, Inc. | Treatment systems, devices, and methods for cooling targeted tissue |
USD777338S1 (en) | 2014-03-20 | 2017-01-24 | Zeltiq Aesthetics, Inc. | Cryotherapy applicator for cooling tissue |
US10952891B1 (en) | 2014-05-13 | 2021-03-23 | Zeltiq Aesthetics, Inc. | Treatment systems with adjustable gap applicators and methods for cooling tissue |
US10568759B2 (en) | 2014-08-19 | 2020-02-25 | Zeltiq Aesthetics, Inc. | Treatment systems, small volume applicators, and methods for treating submental tissue |
US10935174B2 (en) | 2014-08-19 | 2021-03-02 | Zeltiq Aesthetics, Inc. | Stress relief couplings for cryotherapy apparatuses |
US11491342B2 (en) | 2015-07-01 | 2022-11-08 | Btl Medical Solutions A.S. | Magnetic stimulation methods and devices for therapeutic treatments |
US10709894B2 (en) | 2015-07-01 | 2020-07-14 | Btl Medical Technologies S.R.O. | Aesthetic method of biological structure treatment by magnetic field |
US10695576B2 (en) | 2015-07-01 | 2020-06-30 | Btl Medical Technologies S.R.O. | Aesthetic method of biological structure treatment by magnetic field |
US11266850B2 (en) | 2015-07-01 | 2022-03-08 | Btl Healthcare Technologies A.S. | High power time varying magnetic field therapy |
US10478633B2 (en) | 2015-07-01 | 2019-11-19 | Btl Medical Technologies S.R.O. | Aesthetic method of biological structure treatment by magnetic field |
US10821295B1 (en) | 2015-07-01 | 2020-11-03 | Btl Medical Technologies S.R.O. | Aesthetic method of biological structure treatment by magnetic field |
US20180001107A1 (en) | 2016-07-01 | 2018-01-04 | Btl Holdings Limited | Aesthetic method of biological structure treatment by magnetic field |
US10695575B1 (en) | 2016-05-10 | 2020-06-30 | Btl Medical Technologies S.R.O. | Aesthetic method of biological structure treatment by magnetic field |
US10471269B1 (en) | 2015-07-01 | 2019-11-12 | Btl Medical Technologies S.R.O. | Aesthetic method of biological structure treatment by magnetic field |
WO2017070112A1 (fr) | 2015-10-19 | 2017-04-27 | Zeltiq Aesthetics, Inc. | Systèmes de traitement vasculaire, dispositifs de refroidissement et procédés pour refroidir des structures vasculaires |
US11253717B2 (en) | 2015-10-29 | 2022-02-22 | Btl Healthcare Technologies A.S. | Aesthetic method of biological structure treatment by magnetic field |
US10524956B2 (en) | 2016-01-07 | 2020-01-07 | Zeltiq Aesthetics, Inc. | Temperature-dependent adhesion between applicator and skin during cooling of tissue |
US10765552B2 (en) | 2016-02-18 | 2020-09-08 | Zeltiq Aesthetics, Inc. | Cooling cup applicators with contoured heads and liner assemblies |
US11247039B2 (en) | 2016-05-03 | 2022-02-15 | Btl Healthcare Technologies A.S. | Device including RF source of energy and vacuum system |
US11464993B2 (en) | 2016-05-03 | 2022-10-11 | Btl Healthcare Technologies A.S. | Device including RF source of energy and vacuum system |
US11382790B2 (en) | 2016-05-10 | 2022-07-12 | Zeltiq Aesthetics, Inc. | Skin freezing systems for treating acne and skin conditions |
US10555831B2 (en) | 2016-05-10 | 2020-02-11 | Zeltiq Aesthetics, Inc. | Hydrogel substances and methods of cryotherapy |
US11534619B2 (en) | 2016-05-10 | 2022-12-27 | Btl Medical Solutions A.S. | Aesthetic method of biological structure treatment by magnetic field |
US10709895B2 (en) | 2016-05-10 | 2020-07-14 | Btl Medical Technologies S.R.O. | Aesthetic method of biological structure treatment by magnetic field |
US10682297B2 (en) | 2016-05-10 | 2020-06-16 | Zeltiq Aesthetics, Inc. | Liposomes, emulsions, and methods for cryotherapy |
US10583287B2 (en) | 2016-05-23 | 2020-03-10 | Btl Medical Technologies S.R.O. | Systems and methods for tissue treatment |
US10556122B1 (en) | 2016-07-01 | 2020-02-11 | Btl Medical Technologies S.R.O. | Aesthetic method of biological structure treatment by magnetic field |
US20180264282A1 (en) * | 2017-03-16 | 2018-09-20 | Nomir Medical Technologies, Inc. | Specially Designed Kit To Aid Photo-Biologic Eradication Of Staphylococcus Aureus And MRSA In The Nares |
US11076879B2 (en) | 2017-04-26 | 2021-08-03 | Zeltiq Aesthetics, Inc. | Shallow surface cryotherapy applicators and related technology |
EP3829496A1 (fr) | 2018-07-31 | 2021-06-09 | Zeltiq Aesthetics, Inc. | Procédés, dispositifs et systèmes pour l'amélioration d'une ou de plusieurs caractéristiques de la peau |
CN113286630B (zh) | 2019-04-11 | 2024-08-02 | 比特乐医疗方案股份有限公司 | 通过射频和磁能对生物结构进行美容治疗的方法和装置 |
EP3620660B1 (fr) * | 2019-08-06 | 2021-07-28 | Pfeiffer Vacuum Gmbh | Appareil à vide |
CA3173876A1 (fr) | 2020-05-04 | 2021-11-11 | Tomas SCHWARZ | Dispositif et methode pour traitement automatise d'un patient |
US11878167B2 (en) | 2020-05-04 | 2024-01-23 | Btl Healthcare Technologies A.S. | Device and method for unattended treatment of a patient |
EP4415812A1 (fr) | 2021-10-13 | 2024-08-21 | BTL Medical Solutions a.s. | Dispositifs de traitement esthétique de structures biologiques par énergie radiofréquence et magnétique |
US11896816B2 (en) | 2021-11-03 | 2024-02-13 | Btl Healthcare Technologies A.S. | Device and method for unattended treatment of a patient |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2245305T3 (es) * | 1999-04-22 | 2006-01-01 | Veridicom, Inc. | Autenticacion biometrica de alta seguridad usando pares de encriptacion clave publica/clave privada. |
JP2002290397A (ja) * | 2001-03-23 | 2002-10-04 | Iryo Joho Syst Kaihatsu Center | セキュア通信方法 |
US8840608B2 (en) * | 2002-03-15 | 2014-09-23 | The General Hospital Corporation | Methods and devices for selective disruption of fatty tissue by controlled cooling |
JP3786055B2 (ja) * | 2002-06-07 | 2006-06-14 | ソニー株式会社 | データ処理システム、データ処理装置、および方法、並びにコンピュータ・プログラム |
JP4504099B2 (ja) * | 2003-06-25 | 2010-07-14 | 株式会社リコー | デジタル証明書管理システム、デジタル証明書管理装置、デジタル証明書管理方法、更新手順決定方法およびプログラム |
US7713266B2 (en) * | 2005-05-20 | 2010-05-11 | Myoscience, Inc. | Subdermal cryogenic remodeling of muscles, nerves, connective tissue, and/or adipose tissue (fat) |
US8181262B2 (en) * | 2005-07-20 | 2012-05-15 | Verimatrix, Inc. | Network user authentication system and method |
-
2007
- 2007-08-14 JP JP2010516968A patent/JP2010533054A/ja active Pending
- 2007-08-14 WO PCT/US2007/075935 patent/WO2009011708A1/fr active Application Filing
- 2007-08-14 EP EP07800113A patent/EP2182872A1/fr not_active Withdrawn
Non-Patent Citations (1)
Title |
---|
See references of WO2009011708A1 * |
Also Published As
Publication number | Publication date |
---|---|
WO2009011708A1 (fr) | 2009-01-22 |
JP2010533054A (ja) | 2010-10-21 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US9655770B2 (en) | System for treating lipid-rich regions | |
US20090018626A1 (en) | User interfaces for a system that removes heat from lipid-rich regions | |
US20090018624A1 (en) | Limiting use of disposable system patient protection devices | |
US20090018627A1 (en) | Secure systems for removing heat from lipid-rich regions | |
US20090018625A1 (en) | Managing system temperature to remove heat from lipid-rich regions | |
EP2182872A1 (fr) | Système pour traiter des régions riches en lipides | |
US8603073B2 (en) | Systems and methods with interrupt/resume capabilities for treating subcutaneous lipid-rich cells | |
US20230092212A1 (en) | Transcutaneous treatment systems, cooling devices, and methods for cooling nerves | |
US10092346B2 (en) | Combined modality treatment systems, methods and apparatus for body contouring applications | |
EP2346428B1 (fr) | Systèmes et procédés de planification de traitement pour applications de remodelage corporel | |
CN101917944B (zh) | 监视诸如脂肪组织的冷却这种皮下富含脂质的细胞的冷却 | |
US20200237424A1 (en) | System and methods for controlling activation of multiple applicators for tissue treatment | |
CN110013378B (zh) | 具有多个可控冷却元件以提供预定冷却分布曲线的冷却装置 | |
US20160317346A1 (en) | Systems and methods for monitoring cooling of skin and tissue to identify freeze events | |
BRPI0701284B1 (pt) | Sistema para remoção de calor das células subcutâneas ricas em lipídeos |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 20100212 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR |
|
AX | Request for extension of the european patent |
Extension state: AL BA HR MK RS |
|
DAX | Request for extension of the european patent (deleted) | ||
17Q | First examination report despatched |
Effective date: 20130211 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20130622 |