EP2099469A4 - RADIATION PROTECTION AND TREATMENT FOR GAMBLAST EXPOSURE - Google Patents

RADIATION PROTECTION AND TREATMENT FOR GAMBLAST EXPOSURE

Info

Publication number
EP2099469A4
EP2099469A4 EP07874288A EP07874288A EP2099469A4 EP 2099469 A4 EP2099469 A4 EP 2099469A4 EP 07874288 A EP07874288 A EP 07874288A EP 07874288 A EP07874288 A EP 07874288A EP 2099469 A4 EP2099469 A4 EP 2099469A4
Authority
EP
European Patent Office
Prior art keywords
treatment
protection against
gamma ray
ray exposure
against radiation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP07874288A
Other languages
German (de)
English (en)
French (fr)
Other versions
EP2099469A2 (en
Inventor
Wenlin Deng
Veeresa Gududuru
Gangadhar Durgam
Gabor Tigyi
Duane Miller
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Tennessee Research Foundation
Original Assignee
University of Tennessee Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Tennessee Research Foundation filed Critical University of Tennessee Research Foundation
Publication of EP2099469A2 publication Critical patent/EP2099469A2/en
Publication of EP2099469A4 publication Critical patent/EP2099469A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/661—Phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion or mevinphos
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Toxicology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measurement Of Radiation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
EP07874288A 2006-11-15 2007-11-15 RADIATION PROTECTION AND TREATMENT FOR GAMBLAST EXPOSURE Withdrawn EP2099469A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US86587106P 2006-11-15 2006-11-15
PCT/US2007/084875 WO2008140574A2 (en) 2006-11-15 2007-11-15 Radiation protection and treatment for exposure to gamma-radiation

Publications (2)

Publication Number Publication Date
EP2099469A2 EP2099469A2 (en) 2009-09-16
EP2099469A4 true EP2099469A4 (en) 2013-02-27

Family

ID=40002804

Family Applications (1)

Application Number Title Priority Date Filing Date
EP07874288A Withdrawn EP2099469A4 (en) 2006-11-15 2007-11-15 RADIATION PROTECTION AND TREATMENT FOR GAMBLAST EXPOSURE

Country Status (6)

Country Link
EP (1) EP2099469A4 (https=)
JP (1) JP2010510238A (https=)
AU (1) AU2007353320B2 (https=)
CA (1) CA2705612A1 (https=)
IL (1) IL198789A0 (https=)
WO (1) WO2008140574A2 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2935677C (en) * 2013-12-30 2022-07-26 Rama Krishna Reddy SINGIDI Crystalline salts of (z)-o-octadec-9-en-1-yl o,o-dihydrogen phosphorothioate
WO2017011457A1 (en) * 2015-07-12 2017-01-19 The University Of Tennessee Research Foundation Compositions and methods for protecting colonic epithelial barrier function
JPWO2018016523A1 (ja) * 2016-07-20 2019-05-09 国立大学法人 長崎大学 新規放射線防護剤

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005032494A2 (en) * 2003-10-09 2005-04-14 University Of Tennessee Research Foundation Lpa receptor agonists and antagonists and methods of use
WO2007011905A2 (en) * 2005-07-19 2007-01-25 The University Of Tennessee Research Foundation Lpa2 receptor agonist inhibitors of cftr

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005032494A2 (en) * 2003-10-09 2005-04-14 University Of Tennessee Research Foundation Lpa receptor agonists and antagonists and methods of use
WO2007011905A2 (en) * 2005-07-19 2007-01-25 The University Of Tennessee Research Foundation Lpa2 receptor agonist inhibitors of cftr

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
DENG W ET AL: "The Lysophosphatidic Acid Type 2 Receptor Is Required for Protection Against Radiation-Induced Intestinal Injury", GASTROENTEROLOGY, ELSEVIER, PHILADELPHIA, PA, vol. 132, no. 5, 1 May 2007 (2007-05-01), pages 1834 - 1851, XP026856769, ISSN: 0016-5085, [retrieved on 20070505] *
DURGAM G G ET AL: "Synthesis and pharmacological evaluation of second-generation phosphatidic acid derivatives as lysophosphatidic acid receptor ligands", BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, PERGAMON, ELSEVIER SCIENCE, GB, vol. 16, no. 3, 1 February 2006 (2006-02-01), pages 633 - 640, XP027965847, ISSN: 0960-894X, [retrieved on 20060201] *
See also references of WO2008140574A2 *
W DENG: "Lysophosphatidic acid protects and rescues intestinal epithelial cells from radiation- and chemotherapy-induced apoptosis", GASTROENTEROLOGY, vol. 123, no. 1, 1 July 2002 (2002-07-01), pages 206 - 216, XP055050227, ISSN: 0016-5085, DOI: 10.1053/gast.2002.34209 *
WEISDORF D ET AL: "Acute Radiation Injury: Contingency Planning for Triage, Supportive Care, and Transplantation", BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION, KLUGE CARDEN JENNINGS PUBLISHING, CHARLOTTESVILLE, VA, US, vol. 12, no. 6, 1 June 2006 (2006-06-01), pages 672 - 682, XP024918703, ISSN: 1083-8791, [retrieved on 20060601], DOI: 10.1016/J.BBMT.2006.02.006 *

Also Published As

Publication number Publication date
IL198789A0 (en) 2011-08-01
CA2705612A1 (en) 2008-11-20
AU2007353320B2 (en) 2014-01-23
WO2008140574A3 (en) 2009-01-15
WO2008140574A2 (en) 2008-11-20
JP2010510238A (ja) 2010-04-02
AU2007353320A1 (en) 2008-11-20
EP2099469A2 (en) 2009-09-16

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