EP2040746A4 - Verfahren zur rückgewinnung stabilisierter trimerer formulierungen retroviraler hüllproteine - Google Patents
Verfahren zur rückgewinnung stabilisierter trimerer formulierungen retroviraler hüllproteineInfo
- Publication number
- EP2040746A4 EP2040746A4 EP07809720A EP07809720A EP2040746A4 EP 2040746 A4 EP2040746 A4 EP 2040746A4 EP 07809720 A EP07809720 A EP 07809720A EP 07809720 A EP07809720 A EP 07809720A EP 2040746 A4 EP2040746 A4 EP 2040746A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- env
- trimers
- proteins
- processes
- retroviral envelope
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 238000009472 formulation Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 102000004169 proteins and genes Human genes 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 title 1
- 230000001177 retroviral effect Effects 0.000 title 1
- 239000013638 trimer Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/15011—Lentivirus, not HIV, e.g. FIV, SIV
- C12N2740/15022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
- C12N2740/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Virology (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US81511406P | 2006-06-19 | 2006-06-19 | |
PCT/US2007/014388 WO2007149490A1 (en) | 2006-06-19 | 2007-06-19 | Processes for recovering stabilized formulations of trimers of retroviral envelope (env) proteins |
Publications (2)
Publication Number | Publication Date |
---|---|
EP2040746A1 EP2040746A1 (de) | 2009-04-01 |
EP2040746A4 true EP2040746A4 (de) | 2009-12-16 |
Family
ID=38833738
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP07809720A Withdrawn EP2040746A4 (de) | 2006-06-19 | 2007-06-19 | Verfahren zur rückgewinnung stabilisierter trimerer formulierungen retroviraler hüllproteine |
Country Status (3)
Country | Link |
---|---|
EP (1) | EP2040746A4 (de) |
CA (1) | CA2655929A1 (de) |
WO (1) | WO2007149490A1 (de) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
LT3067064T (lt) | 2008-12-09 | 2020-09-10 | Novavax, Inc. | Modifikuoti rsv f baltymai ir jų panaudojimo būdai |
US11446374B2 (en) | 2008-12-09 | 2022-09-20 | Novavax, Inc. | Modified RSV F proteins and methods of their use |
US9738688B2 (en) | 2012-11-05 | 2017-08-22 | International Aids Vaccine Initiative | HIV-1 envelope glycoprotein |
WO2015171975A1 (en) * | 2014-05-09 | 2015-11-12 | The Regents Of The University Of Michigan | Use of modified banana lectin in purification of glycoproteins |
EP3344291A4 (de) | 2015-09-03 | 2019-04-10 | Novavax, Inc. | Impfstoffzusammensetzungen mit verbesserter stabilität und immunogenität |
KR20210004959A (ko) | 2018-03-19 | 2021-01-13 | 노바백스, 인코포레이티드 | 다가 인플루엔자 나노입자 백신 |
KR20220092896A (ko) | 2019-11-07 | 2022-07-04 | 얀센 백신스 앤드 프리벤션 비.브이. | 단백질 정제 |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20050089526A1 (en) * | 2001-09-06 | 2005-04-28 | Moore John P. | Human immunodeficiency virus envelope clycoprotein mutants and uses thereof |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2781676B1 (fr) * | 1998-07-31 | 2004-04-02 | Pasteur Merieux Serums Vacc | Trimere du produit d'expression du gene env de hiv |
CA2520637A1 (en) * | 2003-03-28 | 2004-10-14 | The Government Of The United States Of America, As Represented By The Se Cretary, Department Of Health And Human Services | Mva virus expressing modified hiv envelope, gag, and pol genes |
-
2007
- 2007-06-19 EP EP07809720A patent/EP2040746A4/de not_active Withdrawn
- 2007-06-19 WO PCT/US2007/014388 patent/WO2007149490A1/en active Application Filing
- 2007-06-19 CA CA002655929A patent/CA2655929A1/en not_active Abandoned
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20050089526A1 (en) * | 2001-09-06 | 2005-04-28 | Moore John P. | Human immunodeficiency virus envelope clycoprotein mutants and uses thereof |
Non-Patent Citations (2)
Title |
---|
SANDERS R W ET AL: "Stabilization of the soluble, cleaved, trimeric form of the envelope glycoprotein complex of human immunodeficiency virus type 1", JOURNAL OF VIROLOGY, THE AMERICAN SOCIETY FOR MICROBIOLOGY, US, vol. 76, no. 17, 1 September 2002 (2002-09-01), pages 8875 - 8889, XP002393505, ISSN: 0022-538X * |
See also references of WO2007149490A1 * |
Also Published As
Publication number | Publication date |
---|---|
CA2655929A1 (en) | 2007-12-27 |
WO2007149490A1 (en) | 2007-12-27 |
EP2040746A1 (de) | 2009-04-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 20090115 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR |
|
AX | Request for extension of the european patent |
Extension state: AL BA HR MK RS |
|
RIN1 | Information on inventor provided before grant (corrected) |
Inventor name: BEDDOWS, SIMON Inventor name: MOORE, JOHN P. Inventor name: KANG, YUN Inventor name: IYER, SAI PRASAD N. Inventor name: FRANTI, MICHAEL Inventor name: MADDON, PAUL J. Inventor name: OLSON, WILLIAM C. |
|
A4 | Supplementary search report drawn up and despatched |
Effective date: 20091118 |
|
17Q | First examination report despatched |
Effective date: 20100224 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20100707 |