EP2035093A4 - Procédés pour traiter une lésion de la moelle épinière et pour minimiser l'étendue de la cicatrisation - Google Patents

Procédés pour traiter une lésion de la moelle épinière et pour minimiser l'étendue de la cicatrisation

Info

Publication number
EP2035093A4
EP2035093A4 EP07777388A EP07777388A EP2035093A4 EP 2035093 A4 EP2035093 A4 EP 2035093A4 EP 07777388 A EP07777388 A EP 07777388A EP 07777388 A EP07777388 A EP 07777388A EP 2035093 A4 EP2035093 A4 EP 2035093A4
Authority
EP
European Patent Office
Prior art keywords
methods
spinal cord
cord injury
treating spinal
minimizing scarring
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP07777388A
Other languages
German (de)
English (en)
Other versions
EP2035093A1 (fr
Inventor
Vivienne S Marshall
Diana L Clarke
George L Sing
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Stemnion LLC
Original Assignee
Stemnion LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Stemnion LLC filed Critical Stemnion LLC
Publication of EP2035093A1 publication Critical patent/EP2035093A1/fr
Publication of EP2035093A4 publication Critical patent/EP2035093A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0603—Embryonic cells ; Embryoid bodies
    • C12N5/0605—Cells from extra-embryonic tissues, e.g. placenta, amnion, yolk sac, Wharton's jelly
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/48—Reproductive organs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/90—Serum-free medium, which may still contain naturally-sourced components

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Organic Chemistry (AREA)
  • Reproductive Health (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cell Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Gynecology & Obstetrics (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pregnancy & Childbirth (AREA)
  • Neurosurgery (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
EP07777388A 2006-06-14 2007-06-04 Procédés pour traiter une lésion de la moelle épinière et pour minimiser l'étendue de la cicatrisation Withdrawn EP2035093A4 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US81375906P 2006-06-14 2006-06-14
PCT/US2007/013140 WO2007145889A1 (fr) 2006-06-14 2007-06-04 Procédés pour traiter une lésion de la moelle épinière et pour minimiser l'étendue de la cicatrisation

Publications (2)

Publication Number Publication Date
EP2035093A1 EP2035093A1 (fr) 2009-03-18
EP2035093A4 true EP2035093A4 (fr) 2010-02-17

Family

ID=38832059

Family Applications (1)

Application Number Title Priority Date Filing Date
EP07777388A Withdrawn EP2035093A4 (fr) 2006-06-14 2007-06-04 Procédés pour traiter une lésion de la moelle épinière et pour minimiser l'étendue de la cicatrisation

Country Status (2)

Country Link
EP (1) EP2035093A4 (fr)
WO (1) WO2007145889A1 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101815531B (zh) * 2007-08-22 2015-01-14 斯丹姆涅恩有限公司 含细胞因子溶液的新组合物
KR20140003473A (ko) * 2010-12-17 2014-01-09 안트로제네시스 코포레이션 양막 유래 부착성 세포를 사용한, 척수 손상 및 외상성 뇌 손상의 치료

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006105152A2 (fr) * 2005-03-31 2006-10-05 Stemnion, Inc. Compositions a base de cellules amniotiques, methodes de production et utilisations desdites compositions

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2522890T3 (es) 2000-12-06 2014-11-19 Anthrogenesis Corporation Método para recolectar células troncales placentarias
EP1362095B1 (fr) 2001-02-14 2015-05-27 Anthrogenesis Corporation Placenta post-gravidique de mammifere, son utilisation et cellules souches placentaires correspondantes
DE60233248D1 (de) 2001-11-15 2009-09-17 Childrens Medical Center Verfahren zur isolierung, expansion und differenzierung fötaler stammzellen aus chorionzotte, fruchtwasser und plazenta und therapeutische verwendungen davon
WO2003089619A2 (fr) 2002-04-19 2003-10-30 University Of Pittsburgh Of The Commonwealth System Of Higher Education Cellules souches placentaires et utilisations
US20040161419A1 (en) 2002-04-19 2004-08-19 Strom Stephen C. Placental stem cells and uses thereof
EP1539930A4 (fr) 2002-07-29 2006-08-09 Es Cell Int Pte Ltd Procede en plusieurs etapes de differenciation des cellules sensibles a l'insuline positive, au glucose
US20050152995A1 (en) * 2003-06-27 2005-07-14 Chen Dong F. Methods and compositions for promoting axon regeneration and cell replacement therapy
ES2564044T3 (es) * 2003-06-27 2016-03-17 DePuy Synthes Products, Inc. Células posparto derivadas de tejido del cordón umbilical y métodos de preparación y uso de las mismas
PL1789534T3 (pl) 2004-08-16 2015-03-31 Cellresearch Corp Pte Ltd Wyodrębnienie komórek macierzystych/progenitorowych z błony owodniowej pępowiny
US20060222634A1 (en) 2005-03-31 2006-10-05 Clarke Diana L Amnion-derived cell compositions, methods of making and uses thereof

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006105152A2 (fr) * 2005-03-31 2006-10-05 Stemnion, Inc. Compositions a base de cellules amniotiques, methodes de production et utilisations desdites compositions

Non-Patent Citations (7)

* Cited by examiner, † Cited by third party
Title
DE CASTRO M ET AL: "Evaluation of human serum albumin as a substitute of foetal bovine serum for cell culture", INTERNATIONAL JOURNAL OF PHARMACEUTICS, ELSEVIER BV, NL, vol. 310, no. 1-2, 9 March 2006 (2006-03-09), pages 8 - 14, XP025113345, ISSN: 0378-5173, [retrieved on 20060309], DOI: 10.1016/J.IJPHARM.2005.10.028 *
NORIO SAKURAGAWA ET AL: "Evidence for active acetylcholine metabolism in human amniotic epithelial cells: applicable to intracerebral allografting for neurologic disease", NEUROSCIENCE LETTERS, vol. 232, no. 1, 1 August 1997 (1997-08-01), pages 53 - 56, XP055062974, ISSN: 0304-3940, DOI: 10.1016/S0304-3940(97)00570-3 *
SAKURAGAWA N ET AL: "EXPRESSION OF MARKERS FOR BOTH NEURONAL AND GLIAL CELLS IN HUMAN AMNIOTIC EPITHELIAL CELLS", NEUROSCIENCE LETTERS, LIMERICK, IE, vol. 209, 1 January 1996 (1996-01-01), pages 9 - 12, XP000983495, ISSN: 0304-3940, DOI: 10.1016/0304-3940(96)12599-4 *
SANKAR V ET AL: "Role of human amniotic epithelial cell transplantation in spinal cord injury repair research.", NEUROSCIENCE, vol. 118, no. 1, 25 April 2003 (2003-04-25), pages 11 - 17, XP002562017, ISSN: 0306-4522 *
See also references of WO2007145889A1 *
UCHIDA S ET AL: "NEUROTROPHIC FUNCTION OF CONDITIONED MEDIUM FROM HUMAN AMNIOTIC EPITHELIAL CELLS", JOURNAL OF NEUROSCIENCE RESEARCH, WILEY-LISS, US, vol. 62, no. 4, 15 November 2000 (2000-11-15), pages 585 - 590, XP001029688, ISSN: 0360-4012 *
WU ZHI-YUAN ET AL: "Transplantation of human amniotic epithelial cells improves hindlimb function in rats with spinal cord injury.", CHINESE MEDICAL JOURNAL 20 DEC 2006, vol. 119, no. 24, 20 December 2006 (2006-12-20), pages 2101 - 2107, XP002562018, ISSN: 0366-6999 *

Also Published As

Publication number Publication date
WO2007145889A1 (fr) 2007-12-21
EP2035093A1 (fr) 2009-03-18

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