EP2035093A4 - Methods of treating spinal cord injury and minimizing scarring - Google Patents

Methods of treating spinal cord injury and minimizing scarring

Info

Publication number
EP2035093A4
EP2035093A4 EP07777388A EP07777388A EP2035093A4 EP 2035093 A4 EP2035093 A4 EP 2035093A4 EP 07777388 A EP07777388 A EP 07777388A EP 07777388 A EP07777388 A EP 07777388A EP 2035093 A4 EP2035093 A4 EP 2035093A4
Authority
EP
European Patent Office
Prior art keywords
methods
spinal cord
cord injury
treating spinal
minimizing scarring
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP07777388A
Other languages
German (de)
French (fr)
Other versions
EP2035093A1 (en
Inventor
Vivienne S Marshall
Diana L Clarke
George L Sing
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Stemnion LLC
Original Assignee
Stemnion LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Stemnion LLC filed Critical Stemnion LLC
Publication of EP2035093A1 publication Critical patent/EP2035093A1/en
Publication of EP2035093A4 publication Critical patent/EP2035093A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0603—Embryonic cells ; Embryoid bodies
    • C12N5/0605—Cells from extra-embryonic tissues, e.g. placenta, amnion, yolk sac, Wharton's jelly
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/48—Reproductive organs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/90—Serum-free medium, which may still contain naturally-sourced components

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Organic Chemistry (AREA)
  • Reproductive Health (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cell Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Gynecology & Obstetrics (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pregnancy & Childbirth (AREA)
  • Neurosurgery (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
EP07777388A 2006-06-14 2007-06-04 Methods of treating spinal cord injury and minimizing scarring Withdrawn EP2035093A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US81375906P 2006-06-14 2006-06-14
PCT/US2007/013140 WO2007145889A1 (en) 2006-06-14 2007-06-04 Methods of treating spinal cord injury and minimizing scarring

Publications (2)

Publication Number Publication Date
EP2035093A1 EP2035093A1 (en) 2009-03-18
EP2035093A4 true EP2035093A4 (en) 2010-02-17

Family

ID=38832059

Family Applications (1)

Application Number Title Priority Date Filing Date
EP07777388A Withdrawn EP2035093A4 (en) 2006-06-14 2007-06-04 Methods of treating spinal cord injury and minimizing scarring

Country Status (2)

Country Link
EP (1) EP2035093A4 (en)
WO (1) WO2007145889A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2702809T3 (en) * 2007-08-22 2019-03-05 Noveome Biotherapeutics Inc Novel compositions of solution containing cell factor and its use to treat wounds
JP2014507389A (en) * 2010-12-17 2014-03-27 アントフロゲネシス コーポレーション Treatment of spinal cord injury and traumatic brain injury using amnion-derived adherent cells

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006105152A2 (en) * 2005-03-31 2006-10-05 Stemnion, Inc. Amnion-derived cell compositions, methods of making and uses thereof

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100915482B1 (en) 2000-12-06 2009-09-03 하리리 로버트 제이 Method of collecting placental stem cells
EP2316919B1 (en) 2001-02-14 2015-10-07 Anthrogenesis Corporation Post-partum mammalian placenta, its use and placental stem cells therefrom
ATE438708T1 (en) 2001-11-15 2009-08-15 Childrens Medical Center METHOD FOR ISOLATION, EXPANSION AND DIFFERENTIATION OF FETAL STEM CELLS FROM CHORIONIC VILLY, AMNITION AND PLACENTA AND THERAPEUTIC USES THEREOF
CA2483010A1 (en) 2002-04-19 2003-10-30 University Of Pittsburgh Of The Commonwealth System Of Higher Education Placental derived stem cells and uses thereof
US20040161419A1 (en) 2002-04-19 2004-08-19 Strom Stephen C. Placental stem cells and uses thereof
AU2003257938A1 (en) 2002-07-29 2004-02-16 Es Cell International Pte Ltd. Multi-step method for differentiation of insulin positive, glucose
JP4950660B2 (en) * 2003-06-27 2012-06-13 エチコン、インコーポレイテッド Repair and regeneration of ocular tissue using postpartum cells
WO2005041944A2 (en) * 2003-06-27 2005-05-12 Schepens Eye Research Institute Methods and compositions for promoting axon regeneration and cell replacement therapy
PL1789534T3 (en) 2004-08-16 2015-03-31 Cellresearch Corp Pte Ltd Isolation of stem/progenitor cells from amniotic membrane of umbilical cord
US20060222634A1 (en) 2005-03-31 2006-10-05 Clarke Diana L Amnion-derived cell compositions, methods of making and uses thereof

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006105152A2 (en) * 2005-03-31 2006-10-05 Stemnion, Inc. Amnion-derived cell compositions, methods of making and uses thereof

Non-Patent Citations (7)

* Cited by examiner, † Cited by third party
Title
DE CASTRO M ET AL: "Evaluation of human serum albumin as a substitute of foetal bovine serum for cell culture", INTERNATIONAL JOURNAL OF PHARMACEUTICS, ELSEVIER BV, NL, vol. 310, no. 1-2, 9 March 2006 (2006-03-09), pages 8 - 14, XP025113345, ISSN: 0378-5173, [retrieved on 20060309], DOI: 10.1016/J.IJPHARM.2005.10.028 *
NORIO SAKURAGAWA ET AL: "Evidence for active acetylcholine metabolism in human amniotic epithelial cells: applicable to intracerebral allografting for neurologic disease", NEUROSCIENCE LETTERS, vol. 232, no. 1, 1 August 1997 (1997-08-01), pages 53 - 56, XP055062974, ISSN: 0304-3940, DOI: 10.1016/S0304-3940(97)00570-3 *
SAKURAGAWA N ET AL: "EXPRESSION OF MARKERS FOR BOTH NEURONAL AND GLIAL CELLS IN HUMAN AMNIOTIC EPITHELIAL CELLS", NEUROSCIENCE LETTERS, LIMERICK, IE, vol. 209, 1 January 1996 (1996-01-01), pages 9 - 12, XP000983495, ISSN: 0304-3940, DOI: 10.1016/0304-3940(96)12599-4 *
SANKAR V ET AL: "Role of human amniotic epithelial cell transplantation in spinal cord injury repair research.", NEUROSCIENCE, vol. 118, no. 1, 25 April 2003 (2003-04-25), pages 11 - 17, XP002562017, ISSN: 0306-4522 *
See also references of WO2007145889A1 *
UCHIDA S ET AL: "NEUROTROPHIC FUNCTION OF CONDITIONED MEDIUM FROM HUMAN AMNIOTIC EPITHELIAL CELLS", JOURNAL OF NEUROSCIENCE RESEARCH, WILEY-LISS, US, vol. 62, no. 4, 15 November 2000 (2000-11-15), pages 585 - 590, XP001029688, ISSN: 0360-4012 *
WU ZHI-YUAN ET AL: "Transplantation of human amniotic epithelial cells improves hindlimb function in rats with spinal cord injury.", CHINESE MEDICAL JOURNAL 20 DEC 2006, vol. 119, no. 24, 20 December 2006 (2006-12-20), pages 2101 - 2107, XP002562018, ISSN: 0366-6999 *

Also Published As

Publication number Publication date
EP2035093A1 (en) 2009-03-18
WO2007145889A1 (en) 2007-12-21

Similar Documents

Publication Publication Date Title
EP2088952A4 (en) Methods and devices for treating tissue
EP2007284A4 (en) Devices and methods for treatment of tissue
IL194820A0 (en) Devices and methods for treatment of tissue
HK1150958A1 (en) Devices and methods for treating spinal cord tissue
EP2010232A4 (en) Methods and compositions for the treatment of open and closed wound spinal cord injuries
EP1981463A4 (en) Shock wave treatment device and method of use
GB0624584D0 (en) Skin treatment apparatus and method
EP2169081A4 (en) Reduction treatment apparatus and method of reduction treatment
EP2081638A4 (en) Apparatus and methods for minimally invasive obesity treatment
HK1148232A1 (en) Mucosal tissue dressing and method of use
IL201602A0 (en) Adaptive surgical tourniquet apparatus and method
IL198663A0 (en) Tissue treatment methods
IL187444A0 (en) Tissue treatment device and method
EP2303193A4 (en) Devices and methods for treatment of facet and other joints
EP1864624A4 (en) Surgery assisting apparatus and treatment assisting apparatus
IL230911A0 (en) Apparatus for treating cardiac tissue and use thereof
GB0705617D0 (en) Bone treatment apparatus and method
EP2037812A4 (en) Methods and apparatus for treatment of atrial fibrillation
EP2303160A4 (en) Bone fracture treatment devices and methods of their use
IL198723A0 (en) Methods and compositions for therapeutic treatment
EP1906976A4 (en) Therapeutic polymers and methods of use
EP2263705A4 (en) Therapeutic agent for nerve injury and method for treating nerve injury
EP2023823A4 (en) Vertebral treatment device , system and methods of use
ZA200900489B (en) Apparatus and methods for skin treatment
GB0617505D0 (en) Pneumothorax treatment apparatus and methods

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20081223

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR

AX Request for extension of the european patent

Extension state: AL BA HR MK RS

A4 Supplementary search report drawn up and despatched

Effective date: 20100118

RIC1 Information provided on ipc code assigned before grant

Ipc: A61K 35/50 20060101ALI20100108BHEP

Ipc: A61P 25/00 20060101AFI20080228BHEP

17Q First examination report despatched

Effective date: 20110609

DAX Request for extension of the european patent (deleted)
RIC1 Information provided on ipc code assigned before grant

Ipc: C12N 5/073 20100101AFI20130515BHEP

GRAP Despatch of communication of intention to grant a patent

Free format text: ORIGINAL CODE: EPIDOSNIGR1

INTG Intention to grant announced

Effective date: 20130726

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20131206