EP2021007A2 - Timbre transdermique pour le traitement de la cellulite et de l'adiposité localisée - Google Patents

Timbre transdermique pour le traitement de la cellulite et de l'adiposité localisée

Info

Publication number
EP2021007A2
EP2021007A2 EP07736848A EP07736848A EP2021007A2 EP 2021007 A2 EP2021007 A2 EP 2021007A2 EP 07736848 A EP07736848 A EP 07736848A EP 07736848 A EP07736848 A EP 07736848A EP 2021007 A2 EP2021007 A2 EP 2021007A2
Authority
EP
European Patent Office
Prior art keywords
approximately
patch
amount
patch according
treatment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP07736848A
Other languages
German (de)
English (en)
Inventor
Mario Donnaloja
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Vitrupharma Srl
Original Assignee
Vitrupharma Srl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vitrupharma Srl filed Critical Vitrupharma Srl
Publication of EP2021007A2 publication Critical patent/EP2021007A2/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/06—Preparations for care of the skin for countering cellulitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
    • A61K31/685—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/55—Phosphorus compounds
    • A61K8/553—Phospholipids, e.g. lecithin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Definitions

  • the subject of the present invention is a patch, containing phosphatidylcholine, as well as its use for the treatment of cellulite and localized adiposity.
  • Phosphatidylcholine is a phospholipid that is able to dissolve fat by mere contact and can be either of natural (vegetable, animal, microbial) origin or, possibly, of synthetic origin.
  • phosphatidylcholine For its application in the field of beauty treatment, phosphatidylcholine must, however, be injected into the areas of accumulation of fat, where it is able to reduce the adipocytes (fatty-tissue cells) , in this way bringing about a substantial elimination of localized adiposity.
  • phosphatidylcholine a natural emulsifier
  • phosphatidylcholine a natural emulsifier
  • Phosphatidylcholine could moreover act, also in a minimal concentration, as activator of lipolytic enzymes, in this way bringing about a reduction in the number of the adipocytes themselves.
  • the administration ⁇ in depth" (in the hypodermal fat, i.e., in the fat that lies "under” the derma) is extremely important in order to prevent the risk of serious depressions or even instances of cutaneous necrosis consequent upon wrong modes of administration. Said administration can be made only in a physician' s surgery and must be in any case devised and performed by a surgeon to prevent unpleasant drawbacks.
  • said patch forming the subject of the present invention is simpler and more immediate since it does not require either the user to resort to surgery structures or much less the presence of a medical doctor, since it can be applied directly on the parts to be treated according to the user's own aesthetic needs, without any risk on the latter' s part.
  • Forming then the subject of the present invention is a patch containing phosphatidylcholine for the treatment of cellulite and localized adiposity.
  • the term "patch" is used to indicate a flexible adhesive device, as described in Cosm. Technol. 2000, 3 (1) .
  • present in each individual patch is phosphatidylcholine in an appropriate amount chosen between approximately 5- 500 mg and preferably in an amount of approximately 250 mg.
  • emulsifier sodium desoxycholate in an appropriate amount chosen between approximately 3-300 mg and preferably in an amount of approximately 150 mg.
  • ethoxy diglycol also comprised in the patch forming the subject of the present invention, as promoter of absorption, is ethoxy diglycol, which may be present in an appropriate amount chosen between approximately 0.1-10 mg and preferably in an amount of approximately 3 mg.
  • the patch of the present invention moreover envisages the possible addition, in appropriate amounts, of other known substances for the treatment of cellulite and adiposity, which have different actions: - reducing substances, such as Fucus vescicolosus, caffeine, vegetal xanthine (theophylline and theobromine) , guarana, cola nuts, green tea, Theobroma cacao; and/or - draining substances, such as Ananas sativus; and/or
  • Another aspect of the present invention regards the use of the patch forming the subject of the present invention, containing phosphatidylcholine for the treatment of cellulite and localized adiposity.
  • the patch of the present invention may possibly be applied every day or a number of times a week on the parts of the human body that have localized adiposity and unsightly areas due to cellulite.
  • the patch forming the subject of the present invention can be obviously prepared according to methods known in the art by persons skilled in the branch, adding to the substances mentioned above other ingredients that can be commonly used in the formulation of a patch, such as, for example, adhesives like acrylic copolymers, which can be added in appropriate amounts.

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Birds (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)

Abstract

L'invention concerne un timbre transdermique contenant de la phosphatidylcholine dans une quantité appropriée pour le traitement de la cellulite et de l'adiposité localisée.
EP07736848A 2006-05-18 2007-05-14 Timbre transdermique pour le traitement de la cellulite et de l'adiposité localisée Withdrawn EP2021007A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT000981A ITMI20060981A1 (it) 2006-05-18 2006-05-18 Cerotti medicati atti a trattare cellulite e adiposita' localizzate
PCT/IT2007/000345 WO2007135703A2 (fr) 2006-05-18 2007-05-14 Timbre transdermique pour le traitement de la cellulite et de l'adiposité localisée

Publications (1)

Publication Number Publication Date
EP2021007A2 true EP2021007A2 (fr) 2009-02-11

Family

ID=38521506

Family Applications (1)

Application Number Title Priority Date Filing Date
EP07736848A Withdrawn EP2021007A2 (fr) 2006-05-18 2007-05-14 Timbre transdermique pour le traitement de la cellulite et de l'adiposité localisée

Country Status (3)

Country Link
EP (1) EP2021007A2 (fr)
IT (1) ITMI20060981A1 (fr)
WO (1) WO2007135703A2 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH699835B1 (de) * 2008-02-07 2010-05-14 Mibelle Ag Wasserdispergierbarer oder wasserlöslicher Polymerfilm als Träger von dermatologischen und kosmetischen Wirkstoffen.
ITMI20081862A1 (it) * 2008-10-21 2010-04-22 Funziona Srl Composizione ad uso topico per il trattamento delle adiposita' localizzate e dei relativi inestetismi

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020019445A1 (en) * 1998-08-03 2002-02-14 Easterling W. Jerry Noninvasive method for treating cellulite through transdermal delivery of calcium channel blocker agents and medicament for use in such method
US7041305B2 (en) * 2001-09-07 2006-05-09 Western Holdings, Llc Stable water in oil aminophylline emulsions
ITMI20021280A1 (it) * 2002-06-11 2003-12-11 Carlo Ghisalberti Metodo di trattamento anticellulite
WO2004108140A1 (fr) * 2003-06-05 2004-12-16 Doosan Corporation Composition pour inhiber la differenciation ou la croissance de cellules adipeuses
US7754230B2 (en) * 2004-05-19 2010-07-13 The Regents Of The University Of California Methods and related compositions for reduction of fat
US7763264B2 (en) * 2005-04-26 2010-07-27 John Kulesza Composition and method for reducing the appearance of cellulite

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See references of WO2007135703A2 *

Also Published As

Publication number Publication date
WO2007135703A3 (fr) 2008-04-10
ITMI20060981A1 (it) 2007-11-19
WO2007135703A2 (fr) 2007-11-29

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